Device capable of indwelling arterial duct of rat

Abstract

The utility model relates to an experimental animal surgical instrument, in particular to a device capable of indwelling an arterial duct of a rat. The blood drawing device comprises an intravascular catheter, a subcutaneous catheter and a blood drawing catheter which are sequentially connected through a first fixing knot and a second fixing knot, the intravascular catheter is provided with an oval side hole, and the blood drawing catheter is provided with a rubber piston and an annular application. The intravascular catheter is convenient to operate and place in the blood vessel, and the elliptical side hole conforms to the blood flow direction to improve the blood sampling efficiency; the blood drawing catheter is thick, so that blood can flow out quickly, and biting of rats can be resisted. The fixing joint is of a cylindrical sleeve structure, and the inner diameter is tightly matched with the outer diameter of the catheter. During operation, the catheter in the blood vessel is inserted into the artery, the first fixing knot is bound, then the subcutaneous catheter is laid and penetrates out of the skin to be connected with the blood drawing catheter, then the second fixing knot is bound, finally the annular application is used for fixing, and pricking or piston pulling operation can be directly conducted during blood drawing. The device can reduce damage to rats and improve blood sampling convenience and efficiency.

Description

TECHNICAL FIELD

[0001] The utility model relates to experimental animal surgical instruments, concretely relates to a rat arterial catheter device of indwelling. BACKGROUND

[0002] In the field of biomedical research, especially when using rat experimental models to carry out related work, accurate acquisition of arterial blood samples is of vital importance to the progress of the research and the accuracy of the results. In order to meet the demand of repeated blood sampling, rat arterial catheter devices of indwelling have appeared on the market. However, these existing devices have a series of defects that cannot be ignored.

[0003] When the indwelling catheter is placed in the rat, the rat will inevitably feel annoyed due to the presence of the catheter as a foreign object, which will further cause it to move its body frequently. In this process, the end of the indwelling catheter is extremely easy to come into contact with the blood vessel wall. Due to the complex flow state of blood in the blood vessel and the limitations of the structure of the catheter end, the catheter end may be adsorbed to the inner wall of the blood vessel and blocked by platelets and blood cells to cause thrombosis, thereby causing the catheter to be blocked. Once blocked, it will inevitably seriously affect the blood sampling effect, making the amount of blood sample insufficient, the blood sampling speed slow, or even unable to sample blood, which will greatly interfere with the experimental process.

[0004] Another key problem is that the skin suture wound is prone to inflammation. In the process of leaving the catheter in the rat, the catheter needs to be fixed by skin suture, which will inevitably leave a wound on the rat's skin. Due to the living environment and physiological characteristics of the rat, the wound is easily contaminated by bacteria and microorganisms. At the same time, the existing devices often ignore the effective protection and anti-inflammatory measures for the wound, making the wound face a high risk of inflammation during the healing process. Once the wound is inflamed, it will not only affect the health of the rat, but also may cause local tissue swelling and pain, further intensifying the rat's annoyed mood, prompting it to move its body more violently, thereby increasing the probability of catheter falling off, blocking, etc., and seriously affecting the smooth progress of the experiment. UTILITY MODEL CONTENT

[0005] The utility model aims at overcoming the above problems of the existing rat arterial catheter of indwelling.

[0006] To achieve the above purpose, the technical idea adopted by the utility model to solve its technical problems is:

[0007] Three conduit diameters are designed from small to large, the relatively thick inner diameter of the blood extraction conduit can provide a spacious channel for the rapid outflow of blood, significantly reducing the resistance of blood flow and increasing the rate of blood sample extraction. And the relatively thick blood extraction conduit can resist rat biting to some extent and prevent the conduit from deforming. The side hole of the intravascular conduit is designed in an elliptical shape. When the direction of blood flow is consistent with the direction of the long axis of the ellipse, blood is more likely to enter the side hole, thereby improving the blood sampling efficiency. The annular dressing on the blood extraction conduit has an anti-inflammatory drug adsorbed on the annular dressing portion at the bottom, which can directly act on the skin around the sutured wound to prevent and alleviate inflammatory reactions. The edge of the annular dressing is provided with an annular adhesive portion, which can tightly fix the blood extraction conduit on the surface of the rat skin to prevent the conduit from shaking and shifting, thereby further enhancing the stability of the conduit and reducing the stimulation of the wound caused by the movement of the conduit.

[0008] The rubber piston at the tail of the blood extraction conduit has an arc at the bottom. This design facilitates close cooperation with external blood sampling equipment (such as a syringe), directly inserts the needle to extract blood, and does not cause blood to flow out after the needle is pulled out, so it can be used multiple times. During blood sampling, a good seal is formed to ensure smooth blood sampling operation. If the piston needs to be pulled out for blood extraction, the arc design at the bottom of the piston makes the insertion and removal of the piston in the conduit more smooth, which is convenient for the operator to experiment.

[0009] To achieve the above-mentioned purposes, the technical scheme adopted by the utility model to solve its technical problems is:

[0010] The utility model discloses a rat arterial catheter device can be detained, and the specific scheme is as follows:

[0011] A rat arterial catheter device can be detained, which comprises an intravascular conduit, a subcutaneous conduit and a blood extraction conduit, a fixed knot one is arranged between the intravascular conduit and the subcutaneous conduit, a fixed knot two is arranged between the subcutaneous conduit and the blood extraction conduit, and a side hole is arranged on the intravascular conduit.

[0012] Further, the diameter of the intravascular conduit is smaller than that of the subcutaneous conduit, and the diameter of the subcutaneous conduit is smaller than that of the blood extraction conduit.

[0013] Further, the side hole is in an elliptical shape.

[0014] Further, the blood extraction conduit is provided with an annular dressing, and an anti-inflammatory drug is adsorbed on the annular dressing portion at the bottom of the annular dressing, which is used to prevent the wound of the rat from being inflamed.

[0015] Further, the edge of the annular dressing is provided with an annular adhesive portion, which is used to be fixed on the surface of the rat skin.

[0016] Further, the blood extraction conduit is provided with a rubber piston at the tail, and the rubber piston has an arc at the bottom.

[0017] The utility model has the advantages that:

[0018] 1. In the side of the intravascular catheter, an oval side hole is arranged to avoid the problem of low efficiency of blood sampling caused by the movement of the rat.

[0019] 2. The ring-shaped dressing is sleeved on the blood drawing catheter, which can anti-inflammatory to the wound of the rat and fasten the connection between the catheter and the rat.

[0020] 3. The rubber piston is arranged at the end of the blood drawing catheter to avoid excessive blood flow and facilitate blood sampling. BRIEF DESCRIPTION OF DRAWINGS

[0021] Fig. 1 It is a structural schematic diagram of the utility model;

[0022] Fig. 2 It is a structural schematic diagram of the utility model;

[0023] Among them, the above-mentioned drawings include the following drawing marks:

[0024] 10, intravascular catheter; 101, side hole; 11, subcutaneous catheter; 12, blood drawing catheter; 121, rubber piston; 13, fixed knot one; 14, fixed knot two; 20, ring-shaped dressing; 21, ring-shaped dressing part; 22, ring-shaped adhesive part. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments will be described clearly and completely below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only a part of the embodiments, not all the embodiments.

[0026] In the description of the utility model, it should be understood that the terms "front", "back", "left", "right", "up", "down", "top", "bottom", "inside", "outside" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as a limitation on the utility model.

[0027] Reference Figs. 1-2 The utility model provides a kind of rat arterial catheter device that can be left, including intravascular catheter 10, subcutaneous catheter 11 and blood drawing catheter 12, fixed knot one 13 is arranged between intravascular catheter 10 and subcutaneous catheter 11, fixed knot two 14 is arranged between subcutaneous catheter 11 and blood drawing catheter 12, side hole 101 is arranged on intravascular catheter 10.

[0028] In a specific implementation, the intravascular catheter 10 has a relatively small diameter, for example, about 0.5 mm, which can be suitable for the inner diameter of the rat artery and reduce damage to the blood vessel, and also facilitate the operation and placement in the blood vessel. The length is generally about 3-5 cm, so as to be able to enter the rat artery to a suitable position. The intravascular catheter 10 is provided with a side hole 101, which is elliptical, and the long axis direction of the ellipse is the length direction of the catheter. The design of the elliptical side hole can conform to the blood flow direction to some extent, and when the blood flow direction is consistent with the long axis direction of the ellipse, the blood is more likely to enter the side hole, thereby improving the blood sampling efficiency. The size and number of the side hole can be optimized according to the blood sampling requirement, for example, a plurality of side holes can be provided, and the long axis length of each side hole is about 0.5 mm and the short axis length is about 0.3 mm.

[0029] The subcutaneous catheter 11 has a diameter slightly larger than the intravascular catheter, about 0.8 mm, and is in the shape of an elongated straight cylinder, with a moderate length of about 2-3 cm, which ensures stable passage in the subcutaneous tissue and good transition connection with the intravascular catheter, and does not cause excessive compression to the subcutaneous tissue. It is fixedly connected with the intravascular catheter 10 through the fixing knot one 13.

[0030] The blood extraction catheter 12 has a relatively large diameter, about 1.2 mm. It is a relatively thick tubular structure, and the length is determined according to the actual situation, generally about 5-8 cm, which is convenient for connection and operation with external blood sampling equipment. One end of the blood extraction catheter 12 is connected with the subcutaneous catheter 11 through the fixing knot two 14, and the other end is an open end for connecting the blood sampling equipment or setting a rubber piston 121. The relatively large inner diameter provides a spacious channel for the rapid outflow of blood, reduces the blood flow resistance, and accelerates the blood sampling rate, and also can resist the rat bite to some extent to prevent the catheter from deforming. The rubber piston 121 is made of medical rubber material, and the outer diameter of the bottom is matched with the inner diameter of the blood extraction catheter 12, and the bottom has a curvature, so that it is more smooth when inserted and pulled out of the catheter, and the operator can operate the experiment more conveniently.

[0031] The blood extraction catheter 12 is provided with a ring-shaped patch 20, and the ring-shaped patch 20 is provided with an annular dressing part 21 which is attached to the skin around the sutured wound and adsorbs anti-inflammatory powder. The annular adhesive part 22 is located at the edge of the ring-shaped patch 20 and is annularly arranged around the outer periphery of the annular dressing part 21, and the width thereof can be designed to be 0.5-1 cm, so as to have sufficient adhesive area to firmly fix the rat skin surface.

[0032] The fixing knot one 13 and the fixing knot two 14 are similar to small cylindrical sleeve structures, and the inner diameters thereof are closely matched with the outer diameters of the corresponding catheters.

[0033] In operation, the intravascular catheter 10 is inserted into the rat's arterial blood vessel until the fixation knot 13 is positioned in the blood vessel, and the arterial insertion site is tightly tied with the fixation knot 13 using surgical sutures. The subcutaneous catheter 11 is extended from the rat's skin to the back, and the blood extraction catheter 12 is extended out of the rat's back skin, and the fixation knot 14 between the subcutaneous catheter 11 and the blood extraction catheter 12 is left under the skin, and the skin at the exit site is tightly tied with the fixation knot 14 using surgical sutures. Then, the ring-shaped patch 20 is tightly adhered to the rat's skin surface to prevent the catheters from being displaced, and when blood extraction is needed, the syringe needle is directly inserted into the rubber piston 121, or the rubber piston 121 is pulled out for blood extraction.

[0034] The preferred embodiments of the present application have been described above with the preferred embodiments, but are not intended to limit the present application, and various modifications and changes can be made by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. An indwelling rat arterial catheter device comprising an intravascular catheter (10), a subcutaneous catheter (11) and a blood withdrawal catheter (12), characterized in that, The intravascular catheter (10) and the subcutaneous catheter (11) are provided with a fixed knot one (13), the subcutaneous catheter (11) and the blood drawing catheter (12) are provided with a fixed knot two (14), and the intravascular catheter (10) is provided with a side hole (101).

2. The indwelling rat arterial catheter device of claim 1, wherein, The intravascular catheter (10) is smaller in diameter than the subcutaneous catheter (11), and the subcutaneous catheter (11) is smaller in diameter than the blood drawing catheter (12).

3. The indwelling rat arterial catheter device of claim 1, wherein, The side hole (101) is elliptical, and the long axis direction of the ellipse is the length direction of the catheter.

4. The indwelling rat arterial catheter device of claim 1, wherein, The blood drawing catheter (12) is provided with a ring-shaped patch (20), and the bottom of the ring-shaped patch (20) is provided with a ring-shaped dressing part (21) for adsorbing anti-inflammatory drugs to prevent inflammation of the wound of the rat.

5. The indwelling rat arterial catheter device of claim 4, wherein, The ring-shaped patch (20) is provided with a ring-shaped adhesive part (22) at the edge for fixing with the surface of the skin of the rat.

6. The indwelling rat arterial catheter device of claim 1, wherein, The tail of the blood drawing catheter (12) is provided with a rubber piston (121), and the bottom of the rubber piston (121) is provided with an arc.

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