Acylation kettle for producing acetaminophen

Abstract

The utility model discloses an acylation kettle for acetaminophen production, which relates to the field of acylation reaction equipment, and comprises an acylation kettle and an upper cover, the upper cover is provided with a feeding device and a driving device, the center of the upper cover is rotatably connected with a first stirring device, the first stirring device comprises a main shaft, the main shaft is in transmission connection with the driving device, and the driving device is connected with the acylation kettle. The main shaft is rotatably connected with a second stirring device, two sides of the upper end of the main shaft are fixedly connected with an upper fixing frame, two ends of the upper fixing frame are provided with vertically downward vertical rods, the upper ends of the vertical rods are rotatably connected with a driving gear device, the driving gear device is connected with the second stirring device through a transmission belt, and a lower V-shaped rod is fixedly connected between the lower ends of the two vertical rods; the spiral blades are fixedly connected between the outer ends of the upper fixing frames located on the two sides of the main shaft and the lower ends of the vertical rods, the spiral blades are located on the two sides of the main shaft, reaction liquid in the acylation kettle can be conveyed up and down, stirring is conducted through stirring mechanisms with different rotating speeds, the stirring effect is improved, and the acylation efficiency is improved.

Description

Technical Field

[0001] This utility model belongs to the field of acylation reaction equipment, specifically relating to an acylation reactor for the production of acetaminophen. Background Technology

[0002] Acylation is a very important type of reaction in organic chemistry. It is the process of introducing an acyl group onto carbon, nitrogen, oxygen, or sulfur atoms in organic compound molecules to change the physicochemical properties of the molecules. Acylation reactors are chemical reaction equipment widely used in organic synthesis, pharmaceutical manufacturing, and food processing.

[0003] Chinese Patent Application No. CN202022203706.1 discloses an adjustable acylation reactor, comprising a platform, a cylinder body on the surface of the platform, a first bearing fixedly mounted at the top of the cylinder body, a rotating rod fixedly mounted on the inner wall of the first bearing, a first rotating wheel fixedly mounted at the top of the rotating rod, a first pipe fixedly mounted on the surface of the first rotating wheel, a volumetric flask fixedly mounted at the top of the first pipe, the volumetric flask having graduations on its surface, the bottom end of the first pipe penetrating the interior of the rotating rod, a second pipe fixedly mounted on the surface of the rotating rod, one end of the second pipe penetrating the inner wall of the first pipe, a spray head fixedly mounted on the surface of the second pipe, and a bracket fixedly connected to the surface of the platform. By incorporating a motor, track, gears, and racks, the rotating rod and cylinder body are driven to rotate relative to each other, facilitating the uniform mixing of the acylation reaction materials and ensuring a complete acylation reaction. However, the cylinder in the above device needs to rotate, which leads to unstable operation and high energy consumption. In addition, the reaction liquid in the vessel cannot be transported up and down for mixing, affecting the stirring efficiency. Furthermore, the stirring rod installed on the inner wall of the cylinder, although improving the stirring effect, also makes the equipment difficult to clean and is not conducive to subsequent maintenance. Utility Model Content

[0004] To address the problems mentioned in the background art, this utility model provides an acylation reactor for the production of acetaminophen, which conveys the reaction liquid inside the acylation reactor vertically and uses stirring mechanisms with different rotation speeds to stir the mixture, thereby improving the stirring effect and increasing the acylation efficiency.

[0005] To achieve the above objectives, the specific technical solution of this utility model is as follows:

[0006] An acylation reactor for acetaminophen production includes an acylation reactor and a top cover. The top cover is equipped with a feeding device and a driving device. A first stirring device is rotatably connected to the center of the top cover. The first stirring device includes a main shaft, which is driven by the driving device. A second stirring device is rotatably connected to the main shaft. Upper fixed frames are fixedly connected to both sides of the upper end of the main shaft. Vertically downward vertical rods are provided at both ends of the upper fixed frames. A driving gear device is rotatably connected to the upper end of the vertical rods. The driving gear device is connected to the second stirring device through a transmission belt. A lower V-shaped rod is fixedly connected between the lower ends of the two vertical rods. Spiral blades are fixedly connected between the outer ends of the upper fixed frames located on both sides of the main shaft and the lower ends of the vertical rods. The spiral blades are located on both sides of the main shaft.

[0007] As a further provision of the above scheme, the acylation kettle includes an acylation kettle tank body, a toothed ring is provided at the upper end of the inner wall of the acylation kettle tank body, a lower conical tank is connected to the lower end of the acylation kettle tank body, and a discharge device is provided at the lower end of the lower conical tank.

[0008] As a further provision of the above scheme, the second stirring device includes a rotating sleeve rod, which is rotatably connected to the main shaft. A first pulley is fixedly connected to the upper end of the rotating sleeve rod. The rotating sleeve rod is provided with stirring blades arranged linearly in the upper and lower parts, and the stirring blades are staggered in the upper and lower parts.

[0009] As a further provision of the above scheme, the stirring blade device includes a mounting sleeve, which is fixed on a rotating sleeve rod. Symmetrically arranged connecting rods are fixedly connected to both sides of the mounting sleeve, and stirring blades are fixedly connected to the outer ends of the connecting rods.

[0010] As a further provision of the above scheme, the drive gear device includes a drive gear, which is rotatably connected to the main shaft and axially positioned. The drive gear is meshed with a gear ring, and a second pulley is provided on the lower end face of the drive gear. The second pulley is connected to the first pulley through a transmission belt.

[0011] This utility model has the following beneficial effects:

[0012] The drive unit drives the first stirring device to rotate inside the acylation kettle. The vertical rod and lower V-shaped rod on the first stirring device stir the reaction liquid near the inner wall of the acylation kettle. The spiral blades transport the reaction liquid up and down, improving the stirring effect. When the first stirring device rotates, the drive gear device rotates on the vertical rod under the action of the gear ring, and drives the second stirring device to rotate through the transmission belt. The second stirring device rotates at a different speed than the first stirring device, further improving the stirring effect and increasing the acylation efficiency. Moreover, the structure is simple and reliable, which is conducive to the stable operation of the equipment. Attached Figure Description

[0013] Figure 1 This is a cross-sectional schematic diagram of the present invention;

[0014] Figure 2This is an assembly drawing of the first stirring device and the drive gear device of this utility model;

[0015] Figure 3 This is a schematic diagram of the acylation reactor of this utility model;

[0016] Figure 4 This is an assembly drawing of the second stirring device and the drive gear device of this utility model.

[0017] 1. Acylation kettle; 2. Top cover; 3. Feeding device; 4. Drive device; 5. First stirring device; 6. Second stirring device; 7. Drive gear device; 8. Transmission belt; 9. Discharge device; 101. Acylation kettle body; 1011. Gear ring; 1012. Lower conical tank; 501. Main shaft; 502. Upper fixed frame; 503. Vertical rod; 504. Lower V-shaped rod; 505. Spiral blade; 601. Rotating sleeve rod; 602. First pulley; 603. Stirring blade device; 6031. Mounting bushing; 6032. Connecting rod; 6033. Stirring blade; 701. Drive gear; 702. Second pulley. Detailed Implementation

[0018] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0019] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The following will refer to the appendix... Figures 1-4 This application will be described in detail with reference to the embodiments.

[0020] like Figure 1 , Figure 2As shown, an acylation reactor for acetaminophen production includes an acylation reactor 1 and an upper cover 2. The upper cover 2 is equipped with a feeding device 3 and a driving device 4. A first stirring device 5 is rotatably connected to the center of the upper cover 2. The first stirring device 5 includes a main shaft 501, which is connected to the driving device 4. A second stirring device 6 is rotatably connected to the main shaft 501. Upper fixed frames 502 are fixedly connected to both sides of the upper end of the main shaft 501. Vertically downward vertical rods 503 are provided at both ends of the upper fixed frames 502. A driving gear device 7 is rotatably connected to the upper end of the vertical rods 503. The driving gear device 7 is connected to the second stirring device 6 through a transmission belt 8. A lower V-shaped rod 504 is fixedly connected between the lower ends of the two vertical rods 503. Spiral blades 505 are fixedly connected between the outer ends of the upper fixed frames 502 on both sides of the main shaft 501 and the lower ends of the vertical rods 503. The spiral blades 505 are located on both sides of the main shaft 501.

[0021] like Figure 3 As shown, the acylation reactor 1 includes an acylation reactor tank 101. A toothed ring 1011 is provided at the upper end of the inner wall of the acylation reactor tank 101. A lower conical tank 1012 is connected to the lower end of the acylation reactor tank 101. A discharge device 9 is provided at the lower end of the lower conical tank 1012, which helps with subsequent material discharge.

[0022] like Figure 4 As shown, the second stirring device 6 includes a rotating sleeve 601, which is rotatably connected to the main shaft 501. A first pulley 602 is fixedly connected to the upper end of the rotating sleeve 601. The rotating sleeve 601 is provided with stirring blades 603 arranged linearly in the upper and lower parts. The stirring blades 603 are staggered in the upper and lower parts. The stirring blades 603 include a mounting sleeve 6031, which is fixed to the rotating sleeve 601. Connecting rods 6032 are symmetrically arranged on both sides of the mounting sleeve 6031. Stirring blades 6033 are fixedly connected to the outer ends of the connecting rods 6032.

[0023] The drive gear device 7 includes a drive gear 701, which is rotatably connected to the main shaft 501 and axially positioned. The drive gear 701 is meshed with the gear ring 1011. A second pulley 702 is provided on the lower end face of the drive gear 701. The second pulley 702 is connected to the first pulley 602 through a transmission belt 8.

[0024] The working process of this utility model is as follows: The drive device 4 drives the main shaft 501 to rotate, and the main shaft 501 drives the upper fixed frame 502, the vertical rod 503 and the lower V-shaped rod 504 to rotate, which stirs the reaction liquid near the inner wall of the acylation kettle 1. The spiral blade 503 transports the reaction liquid up and down for exchange and mixing, thereby improving the stirring effect. When the vertical rod 503 rotates, the drive gear 701 is meshed with the gear ring 1011, and the drive gear 701 rotates on the vertical rod 503. The drive gear 701 drives the second pulley 602 to rotate, and the rotation of the second pulley 602 drives the first pulley 602 to rotate through the transmission belt 8, which in turn drives the second stirring device 6 to rotate, and drives the stirring blade device 603 to rotate synchronously. The second stirring device 6 and the first stirring device 5 have different rotation speeds, which further improves the stirring effect.

[0025] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. It will be apparent to those skilled in the art that this utility model is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or basic characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description, and thus all variations falling within the meaning and scope of equivalents of the claims are intended to be included within this utility model.

[0026] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This way of describing the specification is only for clarity. The technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. An acylation still for the production of acetaminophen comprising an acylation still and an upper cover, the upper cover being provided with a feed device and a drive device, characterized in that The first stirring device is rotatably connected at the center of the upper cover, and comprises a main shaft, a driving device, a second stirring device, an upper fixing frame, vertical downward vertical rods, a driving gear device, a lower V-shaped rod, helical blades, and a rotating sleeve rod.

2. The acylation still for acetaminophen production according to claim 1, characterized in that, The acylation kettle comprises an acylation kettle tank body, a tooth ring arranged on the inner wall of the upper end of the acylation kettle tank body, and a lower conical tank connected to the lower end of the acylation kettle tank body.

3. The acylation still for acetaminophen production according to claim 1, wherein The second stirring device comprises a rotating sleeve rod, a first pulley, a stirring blade device, and a first belt.

4. The acylation still for acetaminophen production according to claim 3, wherein The stirring blade device comprises a mounting shaft sleeve, a connecting rod, a stirring blade, and a rotating sleeve rod.

5. The acylation still for acetaminophen production according to claim 3, wherein The driving gear device comprises a driving gear, a tooth ring, a second pulley, and a first belt.

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