Novel tissue embedding box

By designing a novel tissue embedding cassette structure, which employs staggered fixing columns and support plates, the problem of insufficient tissue fixation in traditional embedding cassettes is solved, achieving thorough tissue dehydration and improving the accuracy of pathological diagnosis.

CN223976960UActive Publication Date: 2026-03-06HEBEI PROVINCIAL CHILDRENS HOSPITAL (HEBEI PROVINCIAL FIFTH PEOPLES HOSPITAL HEBEI PROVINCIAL INST OF PEDIATRICS)
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-26
Publication Date
2026-03-06

AI Technical Summary

Technical Problem

In traditional embedding cassettes, the lack of gaps between adjacent layers when placing long strips of tissue leads to insufficient fixation and infiltration, affecting the tissue fixation effect and consequently impacting pathological diagnostic results.

Method used

A novel tissue embedding cassette is designed, employing a lower and upper cassette structure. The lower cassette contains two rows of staggered or corresponding fixing columns, forming a wave-shaped or double-layered placement platform. Combined with a tray and a sealing ring, this ensures full contact between the tissue and the fixative.

Benefits of technology

This process achieves thorough tissue dehydration, ensuring the accuracy of pathological diagnosis, avoiding antigen loss, and improving the success rate of immunohistochemistry and molecular detection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a novel tissue embedding box which comprises a lower box body and an upper box body buckled on the lower box body, one end of the lower box body is connected with one end of the upper box body through an elastic folding plate, groove holes are formed in the bottom face of the lower box body and the top face of the upper box body, a plurality of fixing columns are arranged in the lower box body and located on the bottom face of the lower box body, and the fixing columns are connected with the lower box body. The fixing columns are arranged in two rows and are arranged on the two sides of the width of the lower box body respectively. According to the embedding box disclosed by the utility model, the plurality of fixing columns are arranged in the lower box body of the embedding box, tissues can be placed around the fixing columns when being put into the lower box body, so that the tissues are wavy, gaps are reserved among the tissues, the tissues can be in full contact with fixed liquid, and the complete dehydration of the tissues is facilitated.
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Description

Technical Field

[0001] This utility model relates to a novel tissue embedding cassette. Background Technology

[0002] Embedding cassettes are boxes used to hold sampled tissues. They facilitate tissue fixation and dehydration, and act as scaffolds for embedding tissues, making sectioning easier. They are an indispensable consumable for pathological tissue processing. Traditional embedding cassettes have a conventional box structure. For some long strips of tissue, they are placed in a coiled manner inside the embedding cassette. This results in the tissue layers being too close together with no gaps, which can easily lead to insufficient fixation, dehydration, and infiltration, making tissue fixation inadequate and causing difficulties in slide preparation. Insufficient fixation and dehydration can also cause antigen loss, preventing immunohistochemistry and molecular detection, thus affecting the patient's pathological diagnosis results. Utility Model Content

[0003] The technical problem to be solved by this utility model is to provide a novel tissue embedding box that can place tissues in a wave-like shape, allowing the tissues to undergo sufficient dehydration.

[0004] The technical solution adopted in this utility model is:

[0005] A novel tissue embedding cassette includes a lower cassette and an upper cassette that is fastened to the lower cassette. One end of the lower cassette and the upper cassette are connected by an elastic folding plate. Slots are provided on the bottom surface of the lower cassette and the top surface of the upper cassette. Several fixing posts are provided in the lower cassette and on its bottom surface. The fixing posts are arranged in two rows and are respectively arranged on both sides of the width of the lower cassette.

[0006] Furthermore, the two rows of fixed columns are staggered.

[0007] Furthermore, a connecting hole is provided on the top surface of the fixed column, and a connecting pin that matches the connecting hole is provided on the inner side of the top surface of the upper box. After the upper and lower boxes are fastened together, the connecting pin and the connecting hole cooperate.

[0008] Furthermore, two rows of fixed columns are set up correspondingly, and a support part is provided in the middle of the fixed column.

[0009] Furthermore, the support portion includes several fins disposed on the outer wall of the fixed column, with a gap between adjacent fins.

[0010] Furthermore, a stepped through hole is provided on the front side wall of the lower box, and a blind hole corresponding to the through hole is provided on the rear side wall of the lower box. A support plate is provided in the through hole. The support plate is inserted into the lower box from one side of the through hole, with one end matching the through hole and the other end matching the blind hole.

[0011] Furthermore, a sealing ring is provided at the connection between the tray and the through hole.

[0012] Furthermore, connecting groove A and connecting groove B are provided on the front and rear sides of the lower box body, respectively, and corresponding connecting buckles A and connecting buckles B are provided on the front and rear sides of the upper box body.

[0013] The positive effects of this utility model are:

[0014] This invention features several fixed posts inside the lower box of the embedding cassette. When tissues are placed inside the lower box, they can be arranged around the fixed posts in a wave-like shape, leaving gaps between tissues to ensure full contact with the fixation and dehydration, which is beneficial for complete dehydration of the tissues. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the connecting column of this utility model;

[0017] Figure 3 This is a schematic diagram of the tray of this utility model. Detailed Implementation

[0018] As attached Figure 1-3 As shown, this utility model discloses a novel tissue embedding cassette, including a lower cassette 1 and an upper cassette 2 that can be fastened to the lower cassette 1. A V-shaped elastic folding plate 3 is provided at one end of both the upper and lower cassettes. One end of the elastic folding plate 3 is fixedly connected to the upper cassette 2, and the other end is fixedly connected to the lower cassette 1. Several slots 5 for communicating between the inside and outside of the upper and lower cassettes are provided on the bottom surface of the lower cassette 1 and the top surface of the upper cassette 2. Several fixing posts 6 are provided inside the lower cassette 1 and on its bottom surface. The fixing posts 6 are arranged in two rows on both sides of the width of the lower cassette 1. When placing tissue, the tissue can be arranged around the fixing posts 6. The fixing posts 6 provide support and prevent the tissue from moving within the embedding cassette, thus preventing it from becoming difficult to completely dehydrate.

[0019] The connecting columns 6 of this utility model can be arranged in two ways:

[0020] As an example, the two rows of fixed columns 6 are staggered to form a wave shape, which is consistent with the final shape of the tissue. When the tissue is placed, it wraps around the outside of the fixed columns 6.

[0021] In another embodiment, two rows of fixed columns 6 are arranged in a one-to-one correspondence. A support portion 7 is provided in the middle of each fixed column 6. This support portion 7 consists of several fins evenly distributed on the outer wall of the fixed column 6, with gaps between adjacent fins. All the support portions 7 are on the same plane, forming a placement platform. When tissues need to be placed, they can be placed on the bottom surface of the lower box 1 and within the plane formed by the support portions 7, forming a double-layer arrangement, which is beneficial for placing longer tissues. The gaps between the fins serve two purposes: firstly, they can be used for fixed drainage and flow; secondly, the contact points between the tissue and the edges of the fins can generate a certain force to prevent tissue displacement.

[0022] Preferably, a tray 13 can also be provided inside the lower box body 1. The tray 13 is on the same plane as the supporting part 7 and can also play a supporting role, preventing tissue from sliding off the supporting part 7 due to gravity. Specifically, a stepped through hole 14 is provided on the front side wall of the lower box body 1, and a blind hole corresponding to the through hole 14 is provided on the rear side wall of the lower box body 1. The tray 13 is inserted into the lower box body 1 through the through hole 14, and one end is matched with the blind hole. The other end of the tray 13 is shaped to match the shape of the stepped through hole 14, and a sealing ring is provided at the connection position with the through hole 14. The sealing ring can form a certain force to prevent the tray 13 from moving.

[0023] As a further improvement of this utility model, the length of the connecting post 6 can be sufficiently high so that when the upper and lower boxes are fastened together, the top of the connecting post 6 abuts against the upper box 2. Alternatively, a connecting hole 8 can be provided on the top surface of the connecting post 6, and a connecting pin 10 adapted to the connecting hole 8 can be provided on the inner side of the top surface of the upper box 2. When the upper and lower boxes are fastened together, the connecting pin 10 engages with the connecting hole 8. The upper and lower ends of the connecting post 6 are closed to prevent tissue from detaching from the upper and lower ends of the connecting post 6.

[0024] Connecting grooves A4 and B11 are provided on the front and rear sides of the lower box 1, respectively. Connecting buckles A9 and B12 are provided on the front and rear sides of the upper box 2. After the upper and lower boxes are fastened together, the two connecting buckles are fastened to the corresponding connecting grooves, and the two are connected end to end, making the connection more stable.

[0025] The above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this utility model.

Claims

1. A novel tissue embedding cassette comprising a lower cassette body (1) and an upper cassette body (2) which is snap-fitted to the lower cassette body (1), characterized in that One end of the lower box body (1) and the upper box body (2) is connected through the elastic folding plate (3), the bottom surface of the lower box body (1) and the top surface of the upper box body (2) are provided with the slot hole (5), a plurality of fixing columns (6) are arranged in the lower box body (1) and on the bottom surface thereof, the fixing columns (6) are two rows and are arranged on both sides of the width of the lower box body (1) respectively.

2. A novel tissue embedding cassette according to claim 1, wherein The two rows of fixing columns (6) are arranged staggeredly.

3. The novel tissue embedding cassette of claim 1, wherein The top surface of the fixing column (6) is provided with the connecting hole (8), the inner side of the top surface of the upper box body (2) is provided with the connecting pin (10) matched with the connecting hole (8), and the connecting pin (10) is matched with the connecting hole (8) after the upper and lower box bodies are buckled.

4. The novel tissue embedding box according to claim 1 or 2, characterized in that The two rows of fixing columns (6) are correspondingly arranged, and the supporting part (7) is arranged at the middle position of the fixing column (6).

5. A novel tissue embedding cassette according to claim 4, wherein The supporting part (7) comprises a plurality of fins arranged on the outer side wall of the fixing column (6), and a gap is left between the adjacent two fins.

6. A novel tissue embedding cassette according to claim 5, wherein The stepped through hole (14) is arranged on the front side wall of the lower box body (1), the blind hole corresponding to the through hole (14) is arranged on the rear side wall of the lower box body (1), the supporting plate (13) is arranged in the through hole (14), the supporting plate (13) penetrates into the inside of the lower box body (1) from one side of the through hole (14), one end of the supporting plate (13) is matched with the through hole (14), and the other end of the supporting plate (13) is matched with the blind hole.

7. A novel tissue embedding cassette according to claim 6, wherein The sealing ring is arranged at the connecting position of the supporting plate (13) and the through hole (14).

8. The novel tissue embedding cassette of claim 1, wherein The connecting slot A (4) and the connecting slot B (11) are arranged on the front and rear sides of the lower box body (1) respectively, and the connecting buckle A (9) and the connecting buckle B (12) corresponding to the connecting slot A (4) and the connecting slot B (11) are arranged on the front and rear sides of the upper box body (2).