Temperature adjusting device of microsphere preparation membrane emulsifier

Abstract

The utility model discloses a temperature adjusting device of a microsphere preparation membrane emulsifier, which comprises a support, a dispersed phase groove, a controller, a membrane pipe sleeve and a continuous phase groove which are connected through a pipeline are fixed on the support, the upper end of the dispersed phase groove is connected with an air inlet pipe capable of providing pressure, and an SPG membrane pipe is concentrically placed in a cavity of the membrane pipe sleeve. The SPG membrane tube is fixedly provided with a thermometer, the thermometer is connected with the controller, the lower portion of the membrane tube sleeve is connected with a continuous phase groove through a pipeline, the pipeline is provided with a valve for controlling on-off, and the end, close to the membrane tube sleeve, of the pipeline is provided with a temperature adjusting assembly which is connected with the controller. According to the device, the temperature of a continuous phase can be controlled in the microsphere preparation process, microspheres can be better prepared, meanwhile, the SPG membrane tube can be rapidly replaced, the replacement and use time is shortened, and the microsphere preparation efficiency is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to microsphere preparation technical field, concretely relates to a microsphere preparation membrane emulsifier temperature adjusting device. BACKGROUND

[0002] SPG membrane emulsification technology is a new type of membrane emulsification technology, it can prepare monodisperse emulsion or emulsion bead at low cost. Its working principle is that the dispersed phase is pressurized by nitrogen and then penetrates the membrane hole of the microporous membrane, forming droplets on the surface of the SPG membrane, under the flushing action of the flowing continuous phase, the particle size of the droplets reaches a certain value, then the droplets are stripped from the membrane surface to form emulsion, and after polymerization, the corresponding polymer microparticles are obtained. When emulsifying by membrane emulsification method, the temperature of emulsification is controlled by heating or cooling system to ensure the uniformity of materials and emulsification effect.

[0003] Through the search, the patent with the publication number CN 221846727 U discloses a device for directly preparing monodisperse microspheres by membrane emulsification, a continuous phase tank is connected with one end of a membrane emulsification pipe, one end of the membrane emulsification pipe is connected with a dispersed phase tank at 1 / 3 of the length, the other end of the membrane emulsification pipe is connected with a solidification tank, and the solidification tank is connected with a protection bottle. The continuous phase and the dispersed phase are driven by air pressure, so that the dispersed phase is extruded through the porous membrane pipe in the membrane emulsification pipe under the action of pressure, mixed with the continuous phase to form emulsion with uniform and controllable particle size, and then single dispersed microspheres are obtained through solidification.

[0004] However, the device still has the following problems in use. When controlling the temperature, the temperature of the continuous phase is usually controlled, but after the continuous phase passes through the pump body, especially after the pump body generates heat for a long time, the temperature control of the continuous phase entering the membrane pipe is not accurate, and the membrane pipe is easy to be blocked, and it takes a long time to replace the membrane pipe. UTILITY MODEL CONTENTS

[0005] In order to solve the problems of temperature control of the continuous phase and long time consumption in replacing the membrane pipe in the prior art, a microsphere preparation membrane emulsifier temperature adjusting device is provided to solve the problems of temperature control of the continuous phase entering the membrane pipe and rapid replacement of the membrane pipe.

[0006] The technical solution adopted by the utility model to solve the technical problems is:

[0007] The utility model provides a kind of microsphere preparation membrane emulsifier temperature adjusting device, including support, the support is fixed with the dispersing phase tank connected by pipeline, controller, membrane tube sleeve and continuous phase tank, the upper end of the dispersing phase tank is connected with the gas inlet pipe that can provide pressure, the cavity of the membrane tube sleeve is concentrically placed with SPG membrane tube, the thermometer is fixedly arranged in the SPG membrane tube, the thermometer is connected with the controller, the lower portion of the membrane tube sleeve is connected with the continuous phase tank by pipeline, the pipeline is provided with the valve of control on-off, the one end of the pipeline close to membrane tube sleeve is provided with temperature adjustment component, the temperature adjustment component is connected with the controller.

[0008] Preferably, the temperature adjustment component includes a spiral pipe, the spiral pipe is wound on the pipeline, and the spiral pipe is connected with a low-temperature tank for cooling the pipeline.

[0009] Preferably, the outer wall of the membrane tube sleeve is slidingly connected with a sealing sleeve capable of fixing the SPG membrane tube, the sealing sleeve is slidingly connected with a telescopic guide pin through an elastic member, and the telescopic guide pin can cooperate with the membrane tube sleeve.

[0010] Preferably, the outer wall of the membrane tube sleeve is provided with a sliding groove set cooperating with the telescopic guide pin, the sliding groove set includes a first sliding groove, a second sliding groove and a third sliding groove, the first sliding groove is spirally arranged on the outer wall of the membrane tube sleeve, the third sliding groove is vertically arranged on the outer wall of the membrane tube sleeve, the first sliding groove and the third sliding groove intersect at a certain angle, the second sliding groove is located in the angle region between the first sliding groove and the third sliding groove, and the groove bottom of the second sliding groove is lower than the groove bottoms of the first sliding groove and the third sliding groove.

[0011] Preferably, at least one T-shaped groove is processed on the inner wall of the membrane tube sleeve, a bushing is fixed to the end of the SPG membrane tube, a T-shaped block cooperating with the T-shaped groove is fixed to the bushing, and a thermometer is fixed to the bushing.

[0012] Preferably, a signal contact is connected to the lead wire of the thermometer, the signal contact is fixed to the bushing, a spring needle cooperating with the signal contact is slidingly arranged on the membrane tube sleeve, and the spring needle is connected to the controller through a lead wire.

[0013] Preferably, the valve is a pump body, the inlet end of the pump body extends into the continuous phase tank, and the outlet end of the pump body is connected to the pipeline.

[0014] Preferably, the gas inlet pipe is connected with a gas source station for pressurizing the dispersing phase tank.

[0015] Compared with the prior art, the utility model has the beneficial effects that:

[0016] 1. By thermometer and spiral pipe cooperation, under the action of controller, continuous phase cooling control is realized, so that the microsphere preparation particles have uniformity.

[0017] 2. By the cooperation of the chute group and the sealing sleeve, the SPG membrane tube can be quickly replaced under the assistance of the T-shaped groove, which helps to improve the microsphere preparation efficiency and make the microsphere preparation particles have uniformity. BRIEF DESCRIPTION OF DRAWINGS

[0018] The above and / or additional aspects and advantages of the present application will become apparent and more readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings, in which:

[0019] Figure 1 is a three-dimensional structure schematic diagram of the present application;

[0020] Figure 2 is a front view schematic diagram of the present application;

[0021] Figure 3 is a three-dimensional structure schematic diagram of the present application Figure 2 is a three-dimensional structure schematic diagram of the present application

[0022] Figure 4 is a three-dimensional structure schematic diagram of the present application

[0023] Figure 5 is a three-dimensional structure schematic diagram of the present application Figure 2 is a three-dimensional structure schematic diagram of the present application

[0024] Figure 6 is a three-dimensional structure schematic diagram of the present application Figure 3 is a three-dimensional structure schematic diagram of the present application

[0025] Figure 7 is a three-dimensional structure schematic diagram of the present application Figure 4 is a three-dimensional structure schematic diagram of the present application

[0026] BRIEF DESCRIPTION OF DRAWINGS

[0027] 1. support; 2, dispersed phase tank; 3, pressure relief valve; 4, controller; 5, inlet pipe; 6, membrane sleeve; 7, sealing sleeve; 8, continuous phase tank; 9, pump body; 10, spiral pipe; 11, SPG membrane tube; 12, bushing; 13, T-shaped groove; 14, gasket; 15, thermometer; 16, signal contact; 17, spring needle; 18, steel ball; 19, telescopic guide pin; 20, sliding groove one; 21, sliding groove two; 22, sliding groove three; 23, pipeline. DETAILED DESCRIPTION

[0028] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0029] Example 1:

[0030] like Figure 1 - Figure 7 As shown in the figure, this embodiment proposes a temperature adjustment device for a microsphere preparation membrane emulsifier, including a support 1, which is placed on a flat surface such as a desktop or workbench.

[0031] The support 1 is fixed with a dispersion phase tank 2, a controller 4, a membrane sleeve 6, and a continuous phase tank 8 connected by pipes. The continuous phase tank 8, like the support 1, is placed on a flat surface. The upper end of the dispersion phase tank 2 is connected to an air inlet pipe 5 that can provide pressure. The upper pipe of the dispersion phase tank 2 is also equipped with a pressure relief valve 3, which is located above the intersection of the air inlet pipe 5 and the upper pipe of the dispersion phase tank 2. The lower pipe of the dispersion phase tank 2 is connected to the membrane sleeve 6. The upper part of the membrane sleeve 6 extends into the continuous phase tank 8 through a pipe. The lower part of the membrane sleeve 6 is connected to the continuous phase tank 8 through a pipe 23. An SPG membrane tube 11 is concentrically placed inside the membrane sleeve 6, so that the membrane sleeve 6 and the SPG membrane tube 11 form a shell membrane cavity. A sealing gasket 14 is provided between the upper end of the SPG membrane tube 11 and the membrane sleeve 6.

[0032] Specifically, the air intake pipe 5 is connected to an air source station, which is electrically connected to the controller 4. The air source station is a mature product on the market and is not shown in the figure. The air source station can provide high-pressure gas to the dispersion tank 2. When the pressure in the dispersion tank 2 reaches the threshold, it can be depressurized through the pressure relief valve 3.

[0033] Furthermore, to better achieve the flow of the dispersed phase in the dispersed phase tank 2, the external gas source station uses nitrogen as the pressurized gas supply.

[0034] Specifically, at least one T-groove 13 is machined on the inner wall of the membrane tube sleeve 6. A bushing 12 is fixed to the end of the SPG membrane tube 11. The connection between the SPG membrane tube and the bushing 12 is achieved by a set screw, which is a standard part in the market. A T-block that mates with the T-groove 13 is fixed to the bushing 12. The SPG membrane tube 11 is slid into the membrane tube sleeve 6 by mate between the T-block of the bushing 12 and the T-groove 13. Then the bottom of the membrane tube sleeve 6 is sealed. Then the pipeline 23 is connected through a quick connector, which is a mature accessory product in the market.

[0035] Specifically, the high-pressure gas enters the dispersion phase tank 2 through the gas inlet pipe 5, and the dispersion phase in the dispersion phase tank 2 is pressed into the membrane tube sleeve 6 through the pipeline, and then the dispersion phase penetrates through the SPG membrane tube 11 under the action of high pressure, so that the dispersion phase is pressed into the inner wall of the SPG membrane tube 11, and the continuous phase in the continuous phase tank 8 enters the cavity in the inner wall of the SPG membrane tube 11 through the pipeline 23, and the micro-particles formed by the dispersion phase are taken into the continuous phase tank 8 through the pipeline above the membrane tube sleeve 6.

[0036] Further, in order to better work the continuous phase, the pipeline 23 is provided with a pump body 9 for controlling the on-off, specifically, the pump body 9 is a water pump, which is a mature product in the market, the pump body 9 is electrically connected with the controller 4, the inlet end of the pump body 9 extends into the continuous phase tank 8, the outlet end of the pump body 9 is connected with the pipeline 23, one end of the pipeline 23 close to the membrane tube sleeve 6 is provided with a spiral pipe 10, the spiral pipe 10 is connected with a low-temperature tank for cooling the pipeline 23, the low-temperature tank is a mature product in the market, and a circulating pump for continuously supplying liquid to the spiral pipe 10 is further arranged on the low-temperature tank, the low-temperature tank is connected with the controller 4, the bushing 12 is fixed with a thermometer 15, the lead wire of the thermometer 15 is connected with a signal contact 16, the signal contact 16 is fixed on the bushing 12, the membrane tube sleeve 6 is slidingly provided with a spring needle 17 matched with the signal contact 16, and the spring needle 17 is connected with the controller 4 through the lead wire.

[0037] Specifically, after the SPG membrane tube 11 is installed in place through the T-shaped tank 13, the spring needle 17 is manually pushed to move towards the signal contact 16, so that the spring needle 17 is in contact with the signal contact 16, and then the thermometer 15 is in communication with the controller 4.

[0038] Specifically, the pump body 9 is placed on a plane, and when the pump body 9 works, the continuous phase in the continuous phase tank 8 enters the cavity of the SPG membrane tube 11, so that the continuous phase takes the dispersion phase that has penetrated through the SPG membrane tube 11 under high pressure into the continuous phase tank 8.

[0039] Further, in order to ensure the uniformity and emulsification effect of the material, the continuous phase can be cooled after emulsification through the SPG membrane tube 11, the circulating pump of the low-temperature tank is controlled to work by the controller 4 according to the feedback temperature of the thermometer 15, so that the spiral pipe 10 is continuously supplied with liquid to cool the continuous phase, and better microspheres are prepared.

[0040] Further, the spiral pipe 10 is arranged on the pipeline 23 close to the membrane tube sleeve 6, which can control the temperature of the continuous phase passing through the pipeline 23, avoid the temperature fluctuation of the continuous phase caused by the temperature rise of the pump body 9 caused by the continuous work of the pump body 9, and further avoid the influence of the continuous phase passing through the SPG membrane tube 11 on the uniformity of the microsphere preparation.

[0041] Further, in order to better keep the needle 17 in good contact with the signal contact 16, a steel ball 18 is connected to the cylinder wall of the membrane tube cover 6 through a first spring sliding connection, one end of the first spring is connected to the steel ball 18, and the other end of the first spring is connected to the membrane tube cover 16, and the steel ball 18 is used to position and constrain the needle 17.

[0042] Further, in order to avoid the needle 17 from sliding and affecting the extraction or insertion of the SPG membrane tube 11 when replacing the SPG membrane tube 11, a set of steel balls 18 are arranged on the side away from the signal contact 16, which are used to realize that after the needle 17 is separated from the signal contact 16 by manual operation when replacing the SPG membrane tube 11, the needle 17 is completely located in the cylinder wall of the membrane tube cover 6.

[0043] Embodiment 2:

[0044] As shown in Figure 1 - Figure 7 The other structures are the same as in Embodiment 1, except that in this embodiment, considering that the SPG membrane tube 11 is easy to block in actual use, and it takes a long time to replace the SPG membrane tube 11 and disassemble the membrane tube cover 6, further improvements are made to the fixation of the membrane tube SPG membrane tube 11 based on Embodiment 1.

[0045] The outer wall of the membrane tube cover 6 is provided with a sliding groove set, which includes sliding groove one 20, sliding groove two 21 and sliding groove three 22, the sliding groove one 20 is arranged on the outer wall of the membrane tube cover 6 in a 30° angle helical upward manner, and the sliding groove three 22 is arranged vertically on the outer wall of the membrane tube cover 6, so that the sliding groove one 20 and the sliding groove three 22 intersect at a certain angle, and the sliding groove two 21 is located in the included angle region of the sliding groove one 20 and the sliding groove three 22, and the groove bottom of the sliding groove two 21 is lower than the groove bottom of the sliding groove one 20 and the sliding groove three 22.

[0046] The outer wall of the membrane tube cover 6 is slidingly connected with a matched sealing cover 7, a sealing gasket 14 is arranged between the lower end of the SPG membrane tube 11 and the sealing cover 7, the sealing cover 7 is slidingly connected with a telescopic guide pin 19 through a second spring, one end of the second spring is connected to the telescopic guide pin 19, and the other end of the second spring is connected to the sealing cover 7, the telescopic guide pin 19 can slide into the sliding groove set on the outer wall of the membrane tube cover 6, and the lower part of the sealing cover 7 is connected with a continuous phase tank 8 through a quick connector pipe 23.

[0047] Further, in order to better realize the fixation of the sealing cover 7, the sliding groove set on the outer wall of the membrane tube cover 6 and the telescopic guide pin 19 are symmetrically arranged, which can realize the rotary fixation of the sealing cover 7 under the cooperation of the telescopic guide pin 19 and the sliding groove set.

[0048] Specific, use, the telescopic guide pin 19 on the sealing sleeve 7 slides into the chute one 20, through the rotation sealing sleeve 7 realizes telescopic guide pin 19 in the chute one 20 sliding, chute one 20 is helical upwardly arranged, in turn make sealing sleeve 7 in the sealing gasket 14 and SPG membrane tube 11 contact, and be affected by chute one 20 make sealing sleeve 7 move upwards, when telescopic guide pin 19 slides into the chute two 21 region, under the action of the second spring makes telescopic guide pin 19 card into the chute two 21, complete sealing sleeve 7's fixation.

[0049] Specific, dismounting sealing sleeve 7, through artificial pulling symmetrically arranged two groups of telescopic guide pin 19, make away from the chute two 21, then pull down sealing sleeve 7 without rotation, reduce the power consumption when the operator's both hands are occupied, make telescopic guide pin 19 in the chute three 22 downward sliding can complete dismounting.

[0050] The working principle and use process of the utility model:

[0051] S1: through the controller 4 starts pump body 9 and makes continuous phase tank 8 in continuous phase into SPG membrane tube 11 continuously through pipeline 23;

[0052] Simultaneously gas source station works and makes the pressure in dispersed phase tank 2 increase, realizes the dispersed phase pressure in dispersed phase tank 2 into membrane tube sleeve 6.

[0053] S2: under the continuous pressure, the dispersed phase into membrane tube sleeve 6 penetrates through SPG membrane tube 11, then enters the cavity of SPG membrane tube 11, under the continuous phase provided by pump body 9, makes the dispersed phase that penetrates into into the pipeline above membrane tube sleeve 6 enters continuous phase tank 8;

[0054] Thermometer 15 detects the temperature of the dispersed phase into membrane tube sleeve 6, through controller 4 utilizes low-temperature tank circulating pump to continuously supply liquid to spiral pipe 10, realizes temperature control to continuous phase, makes microsphere preparation have better uniformity.

[0055] S3: when SPG membrane tube 11 needs to be replaced, manually pull symmetrically arranged two groups of telescopic guide pin 19, make telescopic guide pin 19 away from the chute two 21, then pull down sealing sleeve 7 without rotation, make telescopic guide pin 19 in the chute three 22 downward sliding can complete dismounting.

[0056] S4: pull out the elastic needle 17 to the outside, make the elastic needle 17 disengage from the contact with signal contact 16, and realize fixation under the action of a group of steel balls 18 away from signal contact 16.

[0057] S5: pull out SPG membrane tube 16 downwards, loosen the top screw on the bushing 12, can realize separation, after the bushing 12 is placed into new SPG membrane tube 11, fixedly connected.

[0058] S6: sliding the SPG membrane tube 11 into the membrane tube sleeve 6, pushing the elastic needle 17 to make it contact with the signal contact 16 again, and realizing positioning and constraint under the action of the steel ball 18.

[0059] S7: sliding the telescopic guide pin 19 on the sealing sleeve 7 into the sliding groove one 20, realizing the sliding of the telescopic guide pin 19 in the sliding groove one 20 by rotating the sealing sleeve 7, and when the telescopic guide pin 19 slides into the area of the sliding groove two 21, the telescopic guide pin 19 is clamped into the sliding groove two 21 under the action of the second spring, and the fixing of the sealing sleeve 7 is completed.

[0060] Although the embodiments of the utility model have been shown and described, those skilled in the art can understand that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and purposes of the utility model, and the scope of the utility model is defined by the claims and their equivalents.

Claims

1. A temperature adjustment device for a microsphere preparation membrane emulsifier, comprising a support (1), wherein a dispersion phase tank (2), a controller (4), a membrane sleeve (6), and a continuous phase tank (8) connected by pipes are fixed on the support (1), and an air inlet pipe (5) capable of providing pressure is connected to the upper end of the dispersion phase tank (2), characterized in that: An SPG membrane tube (11) is concentrically placed inside the cavity of the membrane tube sleeve (6). A thermometer (15) is fixedly installed on the SPG membrane tube (11). The thermometer (15) is connected to the controller (4). The bottom of the membrane tube sleeve (6) is connected to the continuous phase groove (8) through a pipe (23). The pipe (23) is equipped with a valve to control the on / off state. A temperature adjustment component is provided at one end of the pipe (23) near the membrane tube sleeve (6). The temperature adjustment component is connected to the controller (4).

2. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 1, characterized in that: The temperature adjustment assembly includes a spiral tube (10) wound around the pipeline (23) and the spiral tube (10) is connected to a low-temperature tank for cooling the pipeline (23).

3. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 1, characterized in that: The outer wall of the membrane sleeve (6) is slidably connected to a sealing sleeve (7) that can fix the SPG membrane tube (11). The sealing sleeve (7) is slidably connected to a telescopic guide pin (19) through an elastic element. The telescopic guide pin (19) can cooperate with the membrane sleeve (6).

4. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 3, characterized in that: The outer wall of the membrane sleeve (6) is provided with a set of sliding grooves that cooperate with the telescopic guide pin (19). The set of sliding grooves includes a first sliding groove (20), a second sliding groove (21), and a third sliding groove (22). The first sliding groove (20) is spirally arranged on the outer wall of the membrane sleeve (6), and the third sliding groove (22) is vertically arranged on the outer wall of the membrane sleeve (6). The first sliding groove (20) and the third sliding groove (22) intersect at a certain angle. The second sliding groove (21) is located in the angled area between the first sliding groove (20) and the third sliding groove (22). The bottom of the second sliding groove (21) is lower than the bottom of the first sliding groove (20) and the third sliding groove (22).

5. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 1, characterized in that: At least one T-groove (13) is machined on the inner wall of the membrane tube sleeve (6), a bushing (12) is fixed to the end of the SPG membrane tube (11), a T-shaped block that mates with the T-groove (13) is fixed to the bushing (12), and a thermometer (15) is fixed to the bushing (12).

6. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 5, characterized in that: The thermometer (15) has a wire connected to a signal contact (16), which is fixed on the bushing (12). The membrane sleeve (6) has a spring pin (17) that cooperates with the signal contact (16), and the spring pin (17) is connected to the controller (4) through a wire.

7. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 1, characterized in that: The valve is a pump body (9), the inlet end of which extends into a continuous phase groove (8), and the outlet end of which is connected to the pipeline (23).

8. The temperature adjustment device for the microsphere preparation membrane emulsifier according to claim 1, characterized in that: The air inlet pipe (5) is connected to an air source station for pressurizing the dispersed phase tank (2).

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