Molecular probe capable of conveniently extracting recognizers

Abstract

The utility model discloses a molecular probe convenient to extract an identification object, which comprises a shell, one side of the shell is inserted with a placing box, the top of the placing box is provided with a round hole, the inside of the round hole is rotatably connected with a rotating table, and the inside of the rotating table is provided with a culture assembly used for culturing the molecular probe. The rotating table is driven by the driving assembly to rotate, then the molecular probe in the culture dish is driven to perform rotary culture, the contact area and the contact time of the molecular probe and a culture solution are increased, and therefore the culture efficiency is improved; the mixing and contact of the molecular probe and the culture solution are further promoted, and the culture process is accelerated.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of targeted drug technology, especially to a molecular probe convenient for extracting and identifying objects. BACKGROUND

[0002] The accuracy and enrichment rate of targeted drugs largely determine the clinical diagnosis and treatment effect. Therefore, the accuracy and enrichment rate of targeted drugs should be improved. We designed a visual diagnosis and treatment system based on hierarchical targeting. The system is composed of multifunctional magnetic nanoparticles and biomagnetic materials. The first level targeting mediated by biomagnetism can effectively improve the enrichment rate of drugs in target tissues.

[0003] After retrieval, the utility model discloses a kind of molecular probe convenient for extracting and identifying objects with announcement No.CN214361357U, but the molecular probe still has the following defects when cultivating:

[0004] 1. When taking and placing petri dishes, the operation is too cumbersome, which will waste a lot of time;

[0005] 2. The vibration amplitude of the petri dish cannot be adjusted according to the needs, resulting in a low application range of the device. UTILITY MODEL CONTENT

[0006] The utility model aims at solving the shortcomings in the prior art that the molecular probe is too cumbersome to operate when taking and placing petri dishes, which will waste a lot of time, and the vibration amplitude of the petri dish cannot be adjusted according to the needs, resulting in a low application range of the device, and proposes a molecular probe convenient for extracting and identifying objects.

[0007] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme:

[0008] A molecular probe convenient for extracting and identifying objects, comprising a shell, a placing box is inserted on one side of the shell, a circular hole is formed on the top of the placing box, a rotating table is rotatably connected inside the circular hole, and a culture assembly for culturing molecular probes is arranged inside the rotating table.

[0009] A driving assembly for driving the rotating table to rotate is arranged on the top inner wall of the shell.

[0010] A control assembly for controlling the up-and-down vibration of the molecular probe is arranged on one side of the top of the shell.

[0011] In a preferred embodiment of the utility model, the culture assembly comprises a plurality of placing grooves formed on the top of the rotating table, a sliding block is slidably connected inside the placing groove, a second spring is fixedly connected between the bottom of the sliding block and the bottom of the placing groove, and a petri dish is placed on the top of the sliding block.

[0012] In a preferred embodiment of the utility model, drive assembly including fixedly connected in the top inner wall of shell servo motor, the output shaft of servo motor is fixedly connected with the pivot, the bottom of pivot is fixedly connected with driving gear, the top of placing box is equipped with L type groove, L type groove with round hole bottom side is linked together, the side of L type groove is equipped with the clearance hole that communicates, driving gear is located inside L type groove, the outer wall of rotating platform is fixedly provided with gear ring, gear ring is engaged with driving gear.

[0013] In a preferred embodiment of the utility model, control assembly includes the chute that is equipped in the inner wall of shell side, the inside slide of chute is connected with the sliding block, the side fixed connection of sliding block has the top plate, the inside slide of top plate is equipped with the two limit rods that set up symmetrically, the top of limit rod is fixedly connected with the limit block, the bottom of two limit rods is fixedly connected with same pressing plate, the top of pressing plate and the bottom of top plate are fixedly connected with the two first springs that set up symmetrically, first spring is sleeved on limit rod, the side of pressing plate is equipped with the arc slot.

[0014] In a preferred embodiment of the utility model, the side fixed connection of pressing plate has the lug, the outer wall of pivot is fixedly provided with round plate, the top of round plate is fixedly connected with arc block, arc block is used in cooperation with lug.

[0015] In a preferred embodiment of the utility model, the top rotation of top plate is connected with the lead screw, the top screw of lead screw is fixedly connected with hand wheel and is connected with the shell.

[0016] In a preferred embodiment of the utility model, the outer wall of rotating platform is fixedly provided with annular block, the inner wall of round hole is equipped with annular groove, annular block rotation is connected in the inside of annular groove.

[0017] In a preferred embodiment of the utility model, the side of shell is hinged with the door plate, the bottom of shell four corners are all fixedly connected with the support leg, the side of placing box is equipped with the recess.

[0018] The utility model discloses the beneficial effect is:

[0019] 1. improve the culture efficiency: drive assembly drives rotating platform rotation, and then drive the molecular probe in petri dish to carry out the rotation culture, increase the contact area and contact time of molecular probe and culture solution, thereby improve the culture efficiency.

[0020] 2. reduce external interference: place the box transverse to move to the inside of shell, and close the door plate, can effectively reduce the interference of external environment to the molecular probe culture process, improve the success rate of culture.

[0021] 3. Dynamic culture: the control assembly promotes the mixing and contact of the molecular probe and the culture solution during the up-and-down shaking of the culture dish by periodically lifting and lowering the pressing plate, and accelerates the culture process.

[0022] 4. Wide application range: the height of the top plate is adjusted by rotating the hand wheel, the pressure of the pressing plate on the culture dish is changed, and the amplitude of the up-and-down movement of the culture dish is adjusted, so that the device is suitable for culture of different types and quantities of molecular probes.

[0023] 5. Simple operation: the whole device has simple structure, convenient operation, easy maintenance and cleaning, and low use cost. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 A three-dimensional structure diagram of a molecular probe for facilitating extraction and identification of objects is proposed for the utility model;

[0025] Figure 2 A three-dimensional structure diagram of an outer shell of a molecular probe for facilitating extraction and identification of objects is proposed for the utility model;

[0026] Figure 3 A three-dimensional structure diagram of a pressing plate and a top plate of a molecular probe for facilitating extraction and identification of objects is proposed for the utility model;

[0027] Figure 4 An exploded view of a rotating table and a placing box in a molecular probe for facilitating extraction and identification of objects is proposed for the utility model.

[0028] In the figure: 1, outer shell; 2, hand wheel; 3, top plate; 4, door plate; 5, supporting leg; 6, groove; 7, placing box; 8, arc-shaped groove; 9, pressing plate; 10, sliding groove; 11, servo motor; 12, arc-shaped block; 13, circular plate; 14, rotating shaft; 15, driving gear; 16, lead screw; 17, limiting block; 18, sliding block; 19, first spring; 20, protruding block; 21, limiting rod; 22, L-shaped groove; 23, circular hole; 24, annular groove; 25, accommodation hole; 26, gear ring; 27, placing groove; 28, annular block; 29, rotating table; 30, second spring; 31, sliding block; 32, culture dish. DETAILED DESCRIPTION

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the present application will be briefly introduced below in combination with the drawings and the description of the embodiments or the prior art. Obviously, the following description of the drawings structure is only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained without creative labor on the premise of not paying creative labor. It should be noted that the description of these embodiments is used to help understand the present application, but does not constitute a limitation on the present application.

[0030] Embodiment 1:

[0031] Referring to Figures 1-4 A molecular probe, comprising: a shell 1, one side of the shell 1 is inserted with a placing box 7, a circular hole 23 is opened at the top of the placing box 7, a rotating table 29 is rotatably connected inside the circular hole 23, a culture assembly for culturing the molecular probe is arranged inside the rotating table 29, the culture assembly comprises a plurality of placing grooves 27 opened at the top of the rotating table 29, a sliding block 31 is slidably connected inside the placing groove 27, a second spring 30 is fixedly connected between the bottom of the sliding block 31 and the bottom of the placing groove 27, a culture dish 32 is placed on the top of the sliding block 31, first, when the molecular probe needs to be cultured, the molecular probe is placed in the culture dish 32, then the placing box 7 is pulled out, and then the culture dish 32 is placed inside the rotating table 29, at this time, the bottom of the culture dish 32 is in contact with the bottom of the sliding block 31, part of the culture dish 32 protrudes above the rotating table 29, which can be conveniently contacted with the pressing plate 9, and when the culture dish 32 is taken out later, the part of the culture dish 32 can be taken out, which facilitates the taking of the culture dish 32, and then the placing box 7 is moved horizontally into the shell 1, at this time, the plurality of culture dishes 32 will be in contact with the arc-shaped groove 8 and enter the inside of the placing groove 27, after the door plate 4 is closed, the culture process is carried out, which can avoid the influence of the external environment on the culture of the molecular probe as much as possible, and improve the success rate of the culture of the molecular probe;

[0032] The inner wall of the top of the shell 1 is provided with a drive assembly for driving the rotation of the rotating table 29, the drive assembly comprising a servo motor 11 fixedly connected to the inner wall of the top of the shell 1, the output shaft of the servo motor 11 being fixedly connected with a rotating shaft 14, the bottom of the rotating shaft 14 being fixedly connected with a driving gear 15, the top of the placing box 7 being provided with an L-shaped groove 22, the L-shaped groove 22 being in communication with one side of the bottom of the circular hole 23, one side of the L-shaped groove 22 being provided with a clearance hole 25 in communication, the driving gear 15 being located in the interior of the L-shaped groove 22, the outer wall of the rotating table 29 being fixedly sleeved with a gear ring 26, the gear ring 26 being engaged with the driving gear 15, the servo motor 11 being started, the output shaft of the servo motor 11 driving the rotating shaft 14 to rotate, the rotating shaft 14 driving the driving gear 15 to rotate, the driving gear 15 driving the gear ring 26 to rotate, the gear ring 26 driving the rotating table 29 to rotate, the rotating table 29 driving the annular block 28 to rotate in the interior of the annular groove 24, and driving the plurality of culture dishes 32 in the interior to rotate, so as to improve the culture speed.

[0033] The top of the shell 1 is provided with a control assembly for controlling the up-down vibration of the molecular probe, the control assembly comprising a chute 10 opened in the inner wall of one side of the shell 1, a sliding block 18 being slidably connected in the interior of the chute 10, the sliding block 18 being fixedly connected with a top plate 3 on one side, two limiting rods 21 being symmetrically and slidably penetrated in the interior of the top plate 3, a limiting block 17 being fixedly connected to the top of the limiting rod 21, the bottom of the two limiting rods 21 being fixedly connected with the same pressing plate 9, two first springs 19 being fixedly connected between the top of the pressing plate 9 and the bottom of the top plate 3, the first spring 19 being sleeved on the limiting rod 21, an arc-shaped groove 8 being opened on one side of the pressing plate 9, a protruding block 20 being fixedly connected on one side of the pressing plate 9, a circular plate 13 being fixedly sleeved on the outer wall of the rotating shaft 14, an arc-shaped block 12 being fixedly connected to the top of the circular plate 13, the arc-shaped block 12 being used in cooperation with the protruding block 20, and when the rotating shaft 14 rotates, the circular plate 13 is driven to rotate, the circular plate 13 drives the arc-shaped block 12 to rotate, the arc-shaped block 12 drives the protruding block 20 to move upward, the protruding block 20 drives the pressing plate 9 to move upward, when the arc-shaped block 12 and the protruding block 20 are disengaged, the pressing plate 9 is reset under the elastic force of the first spring 19, when the pressing plate 9 is away from the rotating table 29, the plurality of culture dishes 32 are popped up under the elastic force of the second spring 30, when the pressing plate 9 is reset, the culture dishes 32 are lowered again, and after repeated times, the culture speed can be improved again.

[0034] The present application can be used in the field of targeted drugs, and can also be used in other fields applicable to the present application.

[0035] Example 2

[0036] Reference Figures 1-4On the basis of embodiment 1, improve: a kind of molecular probe for extracting identification object, top rotating connection has lead screw 16 on the top of top plate 3, the top of lead screw 16 is screwed through shell 1 and is fixedly connected with hand wheel 2, the outer wall of rotating table 29 is fixedly sleeved with annular block 28, the inner wall of circular hole 23 is provided with annular groove 24, annular block 28 is rotatably connected in the inside of annular groove 24, the side of shell 1 is hinged with door plate 4, the bottom of shell 1 The four corners are all fixedly connected with support leg 5, recess 6 is formed in the side of placing box 7, and according to actual situation, rotating hand wheel 2, hand wheel 2 drives lead screw 16 to rotate, lead screw 16 drives top plate 3 to move up, top plate 3 drives sliding block 18 to move in the inside of sliding slot 10, simultaneously, the height of pressing plate 9 can be integrally adjusted, so that the amplitude of the multiple petri dishes 32 moving up and down can be changed, the application range of the device is improved.

[0037] Specifically, the working principle of the molecular probe for extracting identification object designed by the utility model is as follows: when using, first, when the molecular probe needs to be cultured, the molecular probe is placed in the petri dish 32, then the placing box 7 is pulled out, and then the petri dish 32 is placed in the inside of the rotating table 29, at this time, the bottom of the petri dish 32 is in contact with the bottom of the sliding block 31, and part of the petri dish 32 protrudes above the rotating table 29, so that the petri dish 32 can be conveniently contacted with the pressing plate 9, and when the petri dish 32 is taken out subsequently, the part of the petri dish 32 that protrudes can be taken out, so that the petri dish 32 is conveniently taken out;

[0038] Then the placing box 7 is moved horizontally into the inside of the shell 1, at this time, the multiple petri dishes 32 will be in contact with the arc-shaped groove 8 and enter the inside of the placing groove 27, after the door plate 4 is closed, the culture process is carried out, so that the culture of the molecular probe is less affected by the external environment, and the success rate of the culture of the molecular probe is improved;

[0039] The servo motor 11 is started, the output shaft of the servo motor 11 drives the rotating shaft 14 to rotate, the rotating shaft 14 drives the driving gear 15 to rotate, the driving gear 15 drives the gear ring 26 to rotate, the gear ring 26 drives the rotating table 29 to rotate, the rotating table 29 drives the annular block 28 to rotate in the inside of the annular groove 24, and drives the multiple petri dishes 32 in the inside to rotate, so that the culture speed is improved;

[0040] And when the rotating shaft 14 rotates, the circular plate 13 is driven to rotate, the circular plate 13 drives the arc-shaped block 12 to rotate, the arc-shaped block 12 drives the protruding block 20 to move up, the protruding block 20 drives the pressing plate to move up, when the arc-shaped block and the protruding block are separated, the pressing plate 9 is reset under the elastic force of the first spring 19, when the pressing plate 9 is away from the rotating table 29, the multiple petri dishes 32 are popped up under the elastic force of the second spring 30, when the pressing plate 9 is reset, the petri dishes 32 are lowered again, and after repeated multiple times, the culture speed can be improved again;

[0041] And can be according to actual situation, rotate hand wheel 2, hand wheel 2 drive screw rotation, screw 16 drive top plate 3 go up, top plate 3 drive slider 18 in the inside of sliding slot 10 move, while can integral adjustment the height of pressing plate 9, and then can change the amplitude of multiple culture dish 32 up and down movement, the application range of lifting device is improved.

[0042] It should be noted that the working principle and wiring method of the servo motor 11 are common, which belong to conventional means or common knowledge, and will not be described here. Those skilled in the art can make any selection according to their needs or convenience.

[0043] Finally, it should be pointed out that: the above only for the preferred embodiments of the present application, and is not used to limit the protection scope of the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A molecular probe for easy extraction of identifiable substances, characterized in that, Include: The shell (1), one side of the shell (1) is inserted with a placement box (7), the top of the placement box (7) is provided with a round hole (23), the inside of the round hole (23) is rotatably connected with a rotating table (29), the inside of the rotating table (29) is provided with a culture assembly for culturing molecular probes, the culture assembly includes a plurality of placement grooves (27) opened in the top of the rotating table (29), the inside of the placement groove (27) is slidably connected with a sliding block (31), the bottom of the sliding block (31) and the bottom of the placement groove (27) are fixedly connected with a same second spring (30), the top of the sliding block (31) is placed with a culture dish (32); The top inner wall of the shell (1) is provided with a driving assembly for driving the rotating table (29) to rotate, the driving assembly includes a servo motor (11) fixedly connected to the top inner wall of the shell (1), the output shaft of the servo motor (11) is fixedly connected with a rotating shaft (14), the bottom of the rotating shaft (14) is fixedly connected with a driving gear (15), the top of the placement box (7) is provided with an L-shaped groove (22), the L-shaped groove (22) is communicated with one side of the bottom of the round hole (23), one side of the L-shaped groove (22) is provided with a communicating gap (25), the driving gear (15) is located in the inside of the L-shaped groove (22), the outer wall of the rotating table (29) is fixedly sleeved with a gear ring (26), the gear ring (26) is engaged with the driving gear (15); The top side of the shell (1) is provided with a control assembly for controlling the up and down vibration of the molecular probe.

2. The molecular probe for easy extraction of identifiable substances according to claim 1, characterized in that, The control assembly includes a chute (10) opened in the inner wall of one side of the shell (1), the inside of the chute (10) is slidably connected with a sliding block (18), one side of the sliding block (18) is fixedly connected with a top plate (3), the inside of the top plate (3) is slidably penetrated with two symmetrically arranged limiting rods (21), the top of the limiting rod (21) is fixedly connected with a limiting block (17), the bottom of the two limiting rods (21) is fixedly connected with a same pressing plate (9), the top of the pressing plate (9) and the bottom of the top plate (3) are fixedly connected with two symmetrically arranged first springs (19), the first spring (19) is sleeved on the limiting rod (21), one side of the pressing plate (9) is provided with an arc-shaped groove (8).

3. The molecular probe for easy extraction of identifiable substances according to claim 2, characterized in that, One side of the pressing plate (9) is fixedly connected with a protruding block (20), the outer wall of the rotating shaft (14) is fixedly sleeved with a circular plate (13), the top of the circular plate (13) is fixedly connected with an arc-shaped block (12), the arc-shaped block (12) is used in cooperation with the protruding block (20).

4. The molecular probe for easy extraction of identifiable substances according to claim 2, characterized in that, The top of the top plate (3) is rotatably connected with a lead screw (16), the top of the lead screw (16) is threadedly penetrated through the shell (1) and fixedly connected with a hand wheel (2).

5. A molecular probe for easy extraction of identifiable substances according to claim 1, characterized in that, The outer wall of the rotating table (29) is fixedly sleeved with an annular block (28), the inner wall of the round hole (23) is provided with an annular groove (24), the annular block (28) is rotatably connected in the inside of the annular groove (24).

6. The molecular probe for facilitating the extraction of identifiable substances according to claim 1, characterized in that, One side of the shell (1) is hinged with a door plate (4), the bottom of the shell (1) is fixedly connected with supporting legs (5) at four corners, and one side of the placing box (7) is provided with a recess (6).

Images