Platelet aggregation function and state detection device and system
By designing a platelet aggregation function and a status detection device, the sample chamber and containment cavity inside the shell are used to distinguish between the sample to be judged and the sample to be tested. The platelet aggregation function is calculated by using light transmittance, which solves the problem of inaccurate results of conventional detection devices and achieves higher detection accuracy and efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2026-03-24
AI Technical Summary
Conventional platelet aggregation function testing devices are prone to producing inaccurate test results.
A platelet aggregation function and status detection device is designed, including a shell, a sample chamber, a buffer zone, a first receiving cavity and a second receiving cavity. The device distinguishes between the sample to be judged and the sample to be tested through a liquid inlet channel and a transparent window, and calculates the platelet aggregation function using light transmittance to ensure the accuracy of the detection results.
It improves the accuracy of platelet aggregation function test results, reduces the difficulty of operation, and increases the testing efficiency.
Smart Images
Figure CN224035249U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the technical field of platelet aggregation function detection, and particularly relates to a platelet aggregation function and state detection device and system. BACKGROUND
[0002] Platelet aggregation function is an important way of platelet participating in the process of stopping blood clotting. Platelet aggregation function detection has important significance in the bleeding and thrombosis risk events such as the efficacy monitoring of anti-platelet drugs, the thrombus risk assessment of high-risk groups and the assessment of surgical bleeding risk.
[0003] The conventional platelet aggregation function detection device usually directly detects the blood sample, so as to easily cause the platelet aggregation detection result to appear error. CONTENT OF UTILITY MODEL
[0004] Therefore, the utility model provides a platelet aggregation function and state detection device and system to solve the problem of inaccurate detection result caused by sample detection by using the conventional platelet aggregation function detection device.
[0005] In the first aspect, the utility model provides a platelet aggregation function and state detection device, which comprises:
[0006] The shell is provided with a sample bin, a buffer area, a first containing cavity and a second containing cavity, the sample bin has an opening facing the outside world, the inlet of the buffer area is communicated with the sample bin through a liquid inlet channel, the first containing cavity and the second containing cavity are arranged in parallel at the bottom of the shell, and are connected to the outlet of the buffer area, the first containing cavity and the second containing cavity are respectively provided with first transparent window and second transparent window facing the same direction, wherein the first containing cavity is suitable for containing the sample to be judged, and the second containing cavity is suitable for containing the sample to be detected.
[0007] Optionally, the outlet of the buffer area is communicated with a liquid outlet channel, the first containing cavity is communicated with the liquid outlet channel through a first liquid distribution channel, and the second containing cavity is communicated with the liquid outlet channel through a second liquid distribution channel.
[0008] Optionally, the bottom wall of the buffer area is a slope, and the outlet is located at the lowest point of the slope.
[0009] Optionally, the buffer area and the sample bin are arranged in parallel and have a gap therebetween, the liquid inlet channel extends from the bottom of the sample bin and is communicated with the inlet of the buffer area through the gap.
[0010] Optionally, a plurality of first containing cavities and a plurality of second containing cavities are arranged side by side at the bottom of the shell.
[0011] Optionally, the sample bin is a cylindrical structure, and a puncture needle is arranged on a bottom wall of the sample bin, the puncture needle is located at a center of the bottom wall of the sample bin, and one end of the puncture needle extends towards the opening, and the other end of the puncture needle penetrates through the bottom wall of the sample bin and communicates with the liquid inlet channel.
[0012] Optionally, a sealing pad is arranged on the bottom wall of the sample bin and sleeved on the puncture needle.
[0013] Optionally, the first accommodating cavity and the second accommodating cavity are respectively provided with a gas-permeable structure in communication with the outside.
[0014] Optionally, the shell is provided with a handle.
[0015] In a second aspect, the utility model provides a kind of platelet aggregation function and state detection system, including the platelet aggregation function and state detection device described above, still including:
[0016] Detection equipment, the detection equipment is provided with the detection site of placing the shell, and the detection equipment is suitable for judging sample state by the first accommodating cavity, and detecting sample result by the second accommodating cavity.
[0017] Beneficial effects:
[0018] The utility model provides a kind of platelet aggregation function and state detection device, including shell. Shell is provided with sample bin, buffer area, first accommodating cavity and second accommodating cavity, sample bin has with the opening to the outside, and the import of buffer area is communicated with sample bin by liquid inlet channel, and first accommodating cavity and second accommodating cavity are arranged in parallel in the bottom of shell, and are connected in the outlet of buffer area, and first accommodating cavity and second accommodating cavity are respectively provided with the first transparent window and the second transparent window of same direction, wherein, first accommodating cavity is suitable for accommodating sample to be judged, and second accommodating cavity is suitable for accommodating sample to be detected.
[0019] When using, sample test tube can be placed from the opening of sample bin, and blood sample can be introduced into buffer area from sample bin through liquid inlet channel and import, and then the blood sample of buffer area is respectively introduced into first accommodating cavity and second accommodating cavity through outlet, so as to divide blood sample into sample to be judged and sample to be detected, sample to be judged is used to judge platelet state, specifically to judge whether platelet occurs aggregation in advance, and sample to be detected is used to detect platelet aggregation function, so as to obtain platelet aggregation function result, if it is judged according to sample to be judged that platelet occurs aggregation in advance, then it is determined that the detection result of platelet aggregation function detected according to sample to be detected is invalid, if it is judged according to sample to be judged that platelet does not occur aggregation in advance, then it is determined that the detection result of platelet aggregation function detected according to sample to be detected is effective. First transparent window and second transparent window can be convenient for cooperating with detection equipment, and detection equipment usually adopts transmittance to calculate platelet aggregation function.
[0020] In this way, the first accommodating cavity and the second accommodating cavity can accommodate the sample to be judged and the sample to be detected respectively, the platelet aggregation function detection result is judged according to whether the platelet aggregation function detection result is effective, if the platelet aggregation function detection result is found to be effective, the sample is re-sampled and the detection is re-performed, so that the platelet aggregation function detection result is ensured to be correct, and the accuracy of the platelet aggregation function detection result is improved.
[0021] In addition, the platelet aggregation function and state detection device provided by the utility model can obtain multiple groups of independent samples to be detected of the same blood sample through the first accommodating cavity and the second accommodating cavity, without being accommodated by multiple reaction cups, and the operator only needs to put the sample test tube into the sample bin opening, and the blood sample can enter the first accommodating cavity and the second accommodating cavity through the liquid inlet channel, the inlet, the buffer area and the outlet, so that the operation difficulty is reduced and the detection efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS
[0022] In order to more clearly illustrate the specific embodiments of the utility model or the technical solutions in the prior art, the following will briefly introduce the drawings needed to be used in the specific embodiments or the prior art description, and obviously, the drawings in the following description are some embodiments of the utility model, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.
[0023] Figure 1 It is a structural schematic view of the platelet aggregation function and state detection device of the utility model embodiment;
[0024] Figure 2 It is an internal structure schematic view of the platelet aggregation function and state detection device of the utility model embodiment;
[0025] Figure 3 It is Figure 1 It is a top view of the platelet aggregation function and state detection device in the utility model;
[0026] Figure 4 It is Figure 1 It is a side view of the platelet aggregation function and state detection device in the utility model;
[0027] Figure 5 It is a structural principle view of the detection equipment of the utility model embodiment;
[0028] Figure 6 It is a structural schematic view of the heating module of the utility model embodiment;
[0029] Figure 7 It is a structural principle view of the heating module of the utility model embodiment.
[0030] BRIEF DESCRIPTION OF DRAWINGS
[0031] 1, housing; 2, handle; 3, sample chamber; 31, gasket; 4, puncture needle; 5, buffer zone; 51, liquid inlet channel; 52, inlet; 53, outlet; 54, first inclined surface; 55, second inclined surface; 6, liquid outlet channel; 71, first sub-liquid channel; 72, second sub-liquid channel; 73, third sub-liquid channel; 74, fourth sub-liquid channel; 81, first containing cavity; 82, second containing cavity; 83, third containing cavity; 84, fourth containing cavity; 9, air outlet; 10, gas channel; 11, air vent; 101, first transparent window; 102, second transparent window; 103, third transparent window; 104, fourth transparent window; 12, heating module. DETAILED DESCRIPTION
[0032] To make the objectives, technical solutions, and advantages of the embodiments of the present application clearer, the following will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are some but not all of the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the present application.
[0033] As shown in Figure 1 and Figure 2 The present application provides a platelet aggregation function and state detection device, which comprises a housing 1.
[0034] The housing 1 is provided with a sample chamber 3, a buffer zone 5, a first containing cavity 81, and a second containing cavity 82. The sample chamber 3 has an opening facing the outside. The inlet 52 of the buffer zone 5 is communicated with the sample chamber 3 through the liquid inlet channel 51. The first containing cavity 81 and the second containing cavity 82 are parallelly arranged at the bottom of the housing 1 and are connected to the outlet 53 of the buffer zone 5. The first containing cavity 81 and the second containing cavity 82 are respectively provided with the first transparent window 101 and the second transparent window 102 facing the same direction. The first containing cavity 81 is suitable for containing a sample to be judged, and the second containing cavity 82 is suitable for containing a sample to be detected.
[0035] In use, the sample tube can be placed into the opening of the sample chamber 3, and the blood sample can pass into the buffer area 5 from the sample chamber 3 through the liquid inlet channel 51 and the inlet 52, and then the blood sample in the buffer area 5 passes into the first holding cavity 81 and the second holding cavity 82 through the outlet 53 respectively, so as to divide the blood sample into a judgment sample and a detection sample, the judgment sample is used to judge the platelet state, specifically to judge whether the platelet has been aggregated in advance, and the detection sample is used to detect the platelet aggregation function, so as to obtain the platelet aggregation function result, if it is judged according to the judgment sample that the platelet has been aggregated in advance, it is determined that the platelet aggregation function detection result detected according to the detection sample is invalid, and if it is judged according to the judgment sample that the platelet has not been aggregated in advance, it is determined that the platelet aggregation function detection result detected according to the detection sample is valid. The first transparent window 101 and the second transparent window 102 can facilitate cooperation with the detection equipment, and the detection equipment usually calculates the aggregation function of the platelet by using the light transmittance.
[0036] In this way, the first holding cavity 81 and the second holding cavity 82 can hold the judgment sample and the detection sample respectively, and whether the platelet aggregation function detection result is valid can be judged according to whether the platelet has been aggregated in advance according to the judgment sample, if it is found that the platelet has been aggregated in advance, the sample can be taken again and the detection can be performed again, so as to ensure that the platelet aggregation function detection result is correct, and the accuracy of the platelet aggregation function detection result is improved.
[0037] In addition, the platelet aggregation function and state detection device provided by the utility model can obtain multiple groups of independent detection samples of the same blood sample through the first holding cavity 81 and the second holding cavity 82 respectively, without the need for multiple reaction cups, and the operator only needs to place the sample tube into the opening of the sample chamber 3, and the blood sample can enter the first holding cavity 81 and the second holding cavity 82 through the liquid inlet channel 51, the inlet 52, the buffer area 5 and the outlet 53 respectively, so as to reduce the operation difficulty and improve the detection efficiency.
[0038] As shown in Figure 2 In the embodiment, the outlet 53 of the buffer area 5 is communicated with the liquid outlet channel 6, the first holding cavity 81 is communicated with the liquid outlet channel 6 through the first liquid distribution channel 71, and the second holding cavity 82 is communicated with the liquid outlet channel 6 through the second liquid distribution channel 72, and the buffering of the buffer area 5 and the distribution of the first liquid distribution channel 71 and the second liquid distribution channel 72 can ensure the consistency of the blood samples in the first holding cavity 81 and the second holding cavity 82.
[0039] As shown in Figure 2As shown, in the embodiment, the bottom wall of the buffer area 5 is inclined, and the outlet 53 is located at the lowest point of the inclined surface. For example, the inclined surface can include a first inclined surface 54 and a second inclined surface 55 on both sides of the outlet 53. The first inclined surface 54 and the second inclined surface 55 can facilitate the blood sample to pass through the outlet 53 into the liquid outlet channel 6 under the action of gravity, thereby avoiding the accumulation of blood in the buffer area 5.
[0040] As shown in FIG. 1, Figure 2 As shown, in the embodiment, the buffer area 5 is arranged in parallel with the sample bin 3 and has a gap therebetween. The liquid inlet channel 51 extends from the bottom of the sample bin 3 and bends to pass through the gap to communicate with the inlet 52 of the buffer area 5. The structure of the shell 1 except the sample bin 3 can be a plate structure. In this way, the compactness of the structure can be improved.
[0041] As shown in FIG. 1, Figure 1 , Figure 2 and Figure 3 As shown, in the embodiment, the sample bin 3 has a cylindrical structure. The bottom wall of the sample bin 3 is provided with the puncture needle 4. The puncture needle 4 is located at the center of the bottom wall of the sample bin 3 and extends in the direction of the opening at one end. The other end of the puncture needle 4 penetrates the bottom wall of the sample bin 3 and communicates with the liquid inlet channel 51. The cylindrical structure of the sample bin 3 can facilitate the alignment with the blood collection tube, so that the blood collection tube can be accurately connected with the puncture needle 4. The puncture needle 4 can penetrate the sealing cover of the blood collection tube, so that the blood can enter the liquid inlet channel 51 through the puncture needle 4.
[0042] As shown in FIG. 1, Figure 2 As shown, in the embodiment, the bottom wall of the sample bin 3 is provided with a sealing pad 31 sleeved on the puncture needle 4. The sealing pad 31 can prevent the blood in the blood collection tube from flowing out from the puncture of the sealing cover.
[0043] As shown in FIG. 1, Figure 2 As shown, in the embodiment, the first accommodating cavity 81 and the second accommodating cavity 82 are respectively provided with a gas permeable structure communicating with the outside. The gas permeable structure can include a gas outlet hole 9 arranged on each accommodating cavity. The gas outlet hole 9 can communicate with the outside, so as to discharge the gas in the accommodating cavity, so that the blood sample can fill the accommodating cavity.
[0044] As shown in FIG. 1, Figure 2 As shown, in the embodiment, the gas permeable structure further includes a gas channel 10 communicating with the plurality of gas outlet holes 9, and an exhaust hole 11 arranged on the gas channel 10. The exhaust hole 11 communicates with the outside. The gas in each accommodating cavity can enter the gas channel 10 through the gas outlet hole 9 of the accommodating cavity, and then be discharged from the exhaust hole 11. The probability of the contact between each accommodating cavity and the outside air is reduced, so as to avoid the pollution of the accommodating cavity.
[0045] As shown in FIG. 1, Figure 2 and Figure 4As shown, in the present embodiment, the shell 1 is provided with a handle 2, which can facilitate the operator to lift the shell 1.
[0046] The principle of the judgment and detection by the platelet aggregation function and state detection device provided by the present embodiment is that when the platelets change from the monodispersion state to the aggregation state, the light signal transmitted through the reaction cup gradually increases. Conversely, the light signal transmitted through the reaction cup gradually decreases. Therefore, the incident light emitter of the detection device can emit incident light to the first transparent window 101 and the second transparent window 102, the transmitted light transmitted through the first transparent window 101 and the second transparent window 102 is received by the transmitted light receiver and a light signal is generated, and the change of the light transmittance represented by the light signal is calculated by the processor to judge the state of the platelets.
[0047] The commonly used platelet disaggregating agents include amikacin, abciximab, tirofiban, RGD (arginine-glycine-aspartic acid) tripeptide and RGD-containing polypeptide. The commonly used platelet activating agents include ADP, AA, adrenaline, ristomycin and collagen, etc. ADP is adenosine diphosphate, and AA is arachidonic acid. Any one of the above platelet disaggregating agents can be added to the first containing cavity 81 for judging the state of the platelets, and the change of the light transmittance is used to judge whether the platelets are aggregated in advance. Any one of the above platelet activating agents can be added to the second containing cavity 82 for detecting the platelet aggregation function, and the change of the light transmittance is used to obtain the platelet aggregation result. Since the platelet disaggregating agents and the platelet activating agents need to be stirred when they act, the magnetic beads wrapped by the platelet disaggregating agents can be placed in the first containing cavity 81, and the magnetic beads wrapped by the platelet activating agents can be placed in the second containing cavity 82, and the stirring can be performed by the magnetic beads.
[0048] For example, amikacin and polytetrafluoroethylene-wrapped magnetic beads are placed in the first containing cavity 81, and the detection device monitors the change of the light transmittance in the first containing cavity 81 in real time. Amikacin can disperse the aggregated platelets, so as to obtain the platelet-rich plasma in the monodispersion state. In this process, the light transmittance of the first transparent window 101 gradually decreases as the platelets are dispersed. The processor of the detection device records the light transmittance T 120 at the time of adding, and records the light transmittance T 125 after the magnetic beads are stirred for 5 minutes. The processor of the detection device calculates the change of the light transmittance of the sample judgment channel according to the formula |T 125 -T 120 | / T 120 , wherein (T 125 -T 120The absolute value of the decrease in the light transmittance of the second transparent window 102 is taken as the divisor of the publicized value. If the decrease in the light transmittance exceeds 2%, it indicates that the platelets have been activated before the start of the detection, the sample is invalid, and the platelet aggregation detection result is unreliable. The platelet aggregation rate detected by the sample detection channel is not reported, and the sample is abnormal. If the decrease in the light transmittance does not exceed 2%, it indicates that the platelets are basically in a monodisperse state at the start of the detection, the sample is valid, and the platelet aggregation detection result is reliable. The platelet aggregation result detected by the sample detection channel is normally reported.
[0049] Similarly, ADP and polytetrafluoroethylene-coated magnetic beads are placed in the second accommodating cavity 82. The ADP can activate the platelets, and the activated platelets gradually aggregate. In this process, the light transmittance of the second transparent window 102 gradually increases with the aggregation of the platelets. The detection equipment monitors the change in the light transmittance of the second accommodating cavity 82 in real time to obtain the platelet aggregation rate. If the platelets are found to have aggregated in advance through the first accommodating cavity 81, the result is invalid.
[0050] To more clearly illustrate how the platelet aggregation function and state detection device provided in the embodiment improves the accuracy of the sample detection result, the following will be described in combination with specific experimental records.
[0051] One volunteer was selected, and two tubes of elbow vein whole blood were continuously extracted, and the anticoagulant was sodium citrate. One tube of sodium citrate anticoagulated venous whole blood sample was selected, centrifuged at 200 g for 10 min, and the upper platelet-rich plasma (PRP) was taken out and transferred into a new blood collection tube. The platelet-rich plasma was mixed vigorously for 30 s to activate the platelets. Then, the blood collection tube was placed into the sample bin 3. The platelet disaggregating agent in the first accommodating cavity 81 was amikacin, and the platelet activator in the second accommodating cavity 82 was ADP. The detection was performed by the detection equipment, and the detection result of the first accommodating cavity 81 was 10%, and the platelet aggregation rate of the second accommodating cavity 82 was 34.7%. Because the result of the first accommodating cavity 81 exceeded the threshold value of 2%, the platelets in the blood collection tube had been activated before being activated by the activator, and the sample was invalid.
[0052] Then, the remaining one tube of sample was centrifuged at 200 g for 10 min, and the upper platelet-rich plasma (PRP) was taken out and transferred into a new blood collection tube. The blood collection tube was placed into a new platelet aggregation function and state detection device sample bin 3, and the detection was performed in the same way as described above. The platelet disaggregating agent in the first accommodating cavity 81 was amikacin, and the platelet activator in the sample detection channel (83 / 84) was ADP. The detection was performed by the detection equipment, and the detection result of the first accommodating cavity 81 was 0.2%, and the platelet aggregation rate of the second accommodating cavity 82 was 81.5%. Because the detection result of the sample judgment channel did not exceed the threshold value of 2%, the sample was valid, and the accurate platelet aggregation rate was obtained.
[0053] This avoids the impact of samples where platelet aggregation has already occurred on platelet aggregation test results, thereby improving the accuracy of the test results.
[0054] like Figure 2 As shown, in this embodiment, multiple first receiving cavities 81 and multiple second receiving cavities 82 are arranged side by side at the bottom of the housing 1. To further improve the accuracy of the detection results, the number of receiving cavities can be increased, thereby allowing for comparative analysis of the state judgment results and aggregation function results of the same blood sample. For example, a third receiving cavity 83 can be added to accommodate the sample to be judged. The third receiving cavity 83 is provided with a third transparent window 103, and the third receiving cavity 83 has the same function as the first receiving cavity 81. A fourth receiving cavity 84 can be added to accommodate the sample to be tested. The fourth receiving cavity 84 is provided with a fourth transparent window 104, and the fourth receiving cavity 84 has the same function as the second receiving cavity 82. Similarly, the third receiving cavity 83 can be connected to the liquid outlet channel 6 through the third liquid dispensing channel 73, and the fourth receiving cavity 84 can be connected to the liquid outlet channel 6 through the fourth liquid dispensing channel 74.
[0055] Of course, you can also set 6, 8, 10 or more cavities, as long as the number of cavities used for judging the sample status is the same as the number of cavities used for sample detection.
[0056] Secondly, this utility model provides a platelet aggregation function and state detection system, including the aforementioned platelet aggregation function and state detection device, and further including:
[0057] The detection device is equipped with a detection position for placing the housing 1. The detection device is suitable for judging the sample status through the first receiving cavity 81 and detecting the sample result through the second receiving cavity 82.
[0058] like Figure 5 As shown, the detection station may include a sample judgment channel and a sample detection channel. The sample judgment channel and the sample detection channel are respectively equipped with a corresponding incident light emitter and a transmitted light receiver. The detection principle of the detection device has been explained in detail above in conjunction with the platelet aggregation function and the usage of the state detection device, and will not be repeated here.
[0059] like Figure 6 and Figure 7As shown, in the embodiment, the detection device further comprises a temperature control module, after the shell 1 is placed in the detection position, the temperature control module 12 can be tightly attached to the shell 1, the temperature control module 12 covers the buffer area 5 and the downstream channel, and the remaining positions are not covered, the sample bin 3 and the area where the containing cavity is located are avoided, during detection, the two sides of the shell 1 can be tightly attached to the temperature control module 12, the shell 1 is uniformly heated by the two temperature control modules 12 arranged oppositely, for example, the temperature control module 12 can be an aluminum block. After the detection device is started, the temperature control module 12 is preheated at a speed of 5℃ / min to 37℃±0.5℃, and then is maintained at 37℃±0.5℃ until the device is turned off, thereby providing the required temperature for detection and ensuring the accuracy of the detection result.
[0060] In addition, the detection device further comprises a processor and a temperature control module 12 connection line connected between the temperature control module 12 and the processor, the processor is used for controlling the temperature of the temperature control module 12, controlling the work of the incident light emitter and the transmitted light receiver, and processing the light signal.
[0061] Although the embodiments of the present application are described in conjunction with the drawings, various modifications and changes can be made by those skilled in the art without departing from the spirit and scope of the present application, and such modifications and changes fall within the scope defined by the appended claims.
Claims
1. A device for detecting platelet aggregation function and status, characterized in that, The application relates to a platelet aggregation function and state detection device, which comprises the following parts: A shell (1) is provided with a sample bin (3), a buffer area (5), a first containing cavity (81) and a second containing cavity (82), the sample bin (3) has an opening facing the outside, an inlet (52) of the buffer area (5) is communicated with the sample bin (3) through a liquid inlet channel (51), the first containing cavity (81) and the second containing cavity (82) are arranged in parallel at the bottom of the shell (1) and are connected to an outlet (53) of the buffer area (5), the first containing cavity (81) and the second containing cavity (82) are respectively provided with first and second transparent windows (101) and (102) facing the same direction, wherein the first containing cavity (81) is suitable for containing a sample to be judged, and the second containing cavity (82) is suitable for containing a sample to be detected.
2. The platelet aggregation function and state detection device according to claim 1, characterized by, The outlet (53) of the buffer area (5) is communicated with a liquid outlet channel (6), the first containing cavity (81) is communicated with the liquid outlet channel (6) through a first liquid distribution channel (71), and the second containing cavity (82) is communicated with the liquid outlet channel (6) through a second liquid distribution channel (72).
3. The platelet aggregation function and state detection device according to claim 2, characterized by, The bottom wall of the buffer area (5) is a slope, and the outlet (53) is located at the lowest point of the slope.
4. The platelet aggregation function and state detection device according to claim 1, wherein The buffer area (5) is arranged in parallel with the sample bin (3) and has a gap therebetween, the liquid inlet channel (51) extends from the bottom of the sample bin (3) and passes through the gap to be communicated with the inlet (52) of the buffer area (5).
5. The platelet aggregation function and status detection device according to any one of claims 1 to 4, characterized by, A plurality of the first containing cavities (81) and a plurality of the second containing cavities (82) are arranged in parallel at the bottom of the shell (1).
6. The platelet aggregation function and status detection device according to any one of claims 1 to 4, characterized by, The sample bin (3) is a cylindrical structure, a puncture needle (4) is arranged on the bottom wall of the sample bin (3), the puncture needle (4) is located at the center of the bottom wall of the sample bin (3), one end of the puncture needle (4) extends to the direction of the opening, and the other end of the puncture needle (4) penetrates through the bottom wall of the sample bin (3) and is communicated with the liquid inlet channel (51).
7. The platelet aggregation function and state detection device according to claim 6, wherein A sealing gasket (31) is arranged on the bottom wall of the sample bin (3) and sleeved on the puncture needle (4).
8. The platelet aggregation function and state detection device according to claim 1, wherein Air permeation structures are arranged on the first containing cavity (81) and the second containing cavity (82) respectively and communicated with the outside.
9. The platelet aggregation function and state detection device according to claim 1, wherein A handle (2) is arranged on the shell (1).
10. A platelet aggregation function and status detection system, characterized by, The platelet aggregation function and state detection device comprises the blood platelet aggregation function and state detection device according to any one of claims 1 to 9, and further comprises: A detection device is provided with a detection position for placing the shell (1), the detection device is suitable for judging the sample state through the first containing cavity (81) and detecting the sample result through the second containing cavity (82).