Composite stent for bone tissue engineering

Abstract

The utility model relates to the technical field of medical instruments, and discloses a composite support for bone tissue engineering, which comprises a shell, a plurality of fixing rings are equidistantly mounted on the outer wall of a supporting layer, a filter screen is mounted in the middle of the outer wall of each fixing ring, and a fixing block is fixedly connected to the bottom end of each fixing ring. A bottom plate is fixedly connected to the bottom end of the fixing block, a connecting pipe is fixedly connected to the middle of the top end of the bottom plate, a plurality of second medicine outlet holes are formed in the top wall of the bottom plate at equal intervals, a second cavity is formed in the middle of the fixing block and the middle of the connecting pipe, and a first cavity is formed in the middle of the shielding layer and the middle of the supporting layer. According to the utility model, the cavity I can be filled with medicines for diminishing inflammation, relieving pain, resisting infection and promoting cartilage growth, the medicines enter the connecting tube and then flow into the adjacent cavity II from the groove, and then the medicines are guided to a fracture area through the medicine outlet II, so that smooth and rapid growth of bone tissue cells can be effectively promoted, and damaged bone tissue can be repaired.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field especially relates to a kind of composite scaffold for bone tissue engineering. BACKGROUND

[0002] Bone tissue engineering is a multi-disciplinary frontier field, aims at using the principles and methods of engineering and life science, develops technology and material that can repair, replace and regenerate bone tissue, to solve bone defect, bone disease these clinical problems.

[0003] Natural polymer material, as the scaffold material of bone tissue engineering, needs to have good biocompatibility, biodegradability, bone conduction and certain mechanical strength, constructs bone tissue substitute in vitro, for tissue repair and regenerative medicine research, such as through 3D printing composite scaffold combined with stem cell culture, constructs bone tissue with certain function.

[0004] Prior art obtains seed cell under suitable culture condition through in vitro cell culture technology, to obtain enough quantity of cell for tissue engineering construction, while adding various growth factors and inducing agent in culture process, directional induction cell to osteoblast differentiation, constructs the bone tissue engineering graft to be implanted into bone defect site, through the osteogenesis of seed cell, the bone conduction and induction of biomaterial and the regulation effect of growth factor, promotes the regeneration and repair of bone tissue, but for some scaffolds with highly complex microstructure and macroscopic shape, manufacturing process still has certain limit, it is difficult to accurately manufacture composite scaffold that has good biocompatibility and biological activity, and can meet the needs of complex shape and structure of specific anatomical site, constantly improve and innovate manufacturing technology, such as developing high-resolution 3D printing technology, electrospinning and 3D printing combined technology, improve the ability of manufacturing complex structure composite scaffold, but still exist the shortcomings that autologous bone graft donor deficiency and bone recovery will produce discomfort. UTILITY MODEL CONTENT

[0005] In order to make up for the above shortcomings, the utility model provides a kind of composite scaffold for bone tissue engineering, to improve the problem of autologous bone graft donor deficiency and bone recovery will produce discomfort in prior art.

[0006] In order to achieve the above object, the utility model discloses the following technical scheme: a kind of composite scaffold for bone tissue engineering, including shell, the inner side of the shell is fixedly connected with shielding layer, the inner side of the shielding layer is installed with support layer, the outer wall of the support layer is installed with multiple fixed rings equidistantly, the outer wall middle part of the fixed ring is installed with filter screen, the bottom end of the fixed ring is fixedly connected with fixed block, the bottom end of the fixed block is fixedly connected with bottom plate, the top end of the bottom plate is fixedly connected with connecting pipe, the top wall of the bottom plate is equidistantly provided with multiple medicine outlet holes two, the middle part of the fixed block and connecting pipe is provided with cavity two, the outer wall of the connecting pipe is equidistantly provided with multiple grooves, the middle part of the shielding layer and support layer is provided with cavity one, the front and rear ends of the cavity one are installed with sealing ring, the outer wall of the sealing ring is equidistantly provided with multiple medicine outlet holes one, the outer wall rear side of the shell is equidistantly fixedly connected with multiple connecting pieces, the middle part of the connecting piece is rotatably connected with connecting rod, the inner wall of the shielding layer is equidistantly installed with multiple buffering mechanism, and the buffering mechanism is used to reduce the influence of vibration on fracture area.

[0007] As further description of the above technical solution:

[0008] The buffering mechanism includes connecting block, the connecting block is equidistantly installed on the inner wall of the shielding layer, the inner side of the connecting block is provided with cavity, the inner bottom wall of the cavity is installed with damping rod, the outer wall of the damping rod is installed with spring, the end of the damping rod is fixedly connected with protruding block, and the top end of the protruding block is fixedly connected with soft block.

[0009] As further description of the above technical solution:

[0010] The outer wall front side of the shell is fixedly connected with mounting block, and the outer wall right side of the mounting block is installed with knob.

[0011] As further description of the above technical solution:

[0012] The end of the knob is fixedly connected with rotating shaft, and the end of the rotating shaft is fixedly connected with gear.

[0013] As further description of the above technical solution:

[0014] The outer wall of the rotating shaft is installed with cross brace, and the inner wall top of the mounting block is fixedly connected with cross brace.

[0015] As further description of the above technical solution:

[0016] The left side of the gear is installed with clamping block, and the middle part of the clamping block is provided with sliding slot.

[0017] As further description of the above technical solution:

[0018] The inner wall of the mounting block is provided with a fixing rod, and a plurality of clamping grooves are equidistantly formed in the outer wall of the fixing rod.

[0019] As a further description of the above technical solution:

[0020] The left side of the gear is engaged with a rack, and the rack is slidingly connected to the inner wall of the sliding groove.

[0021] The utility model has the advantages of the following:

[0022] 1、The cavity one can fill the medicine of anti-inflammatory, analgesic, anti-infection and promoting cartilage growth, the filter screen is convenient for the medicine to enter the connecting pipe, the medicine enters the connecting pipe and then flows into the adjacent cavity two area from the groove, then the medicine is guided to the support layer and the bone contact area through the medicine outlet hole two, can effectively promote the smooth and rapid growth of bone tissue cells, and repair the damaged bone tissue.

[0023] 2、The shell and the shielding layer will impact the support layer when vibration is generated, the soft block will touch the support layer, the soft block will be blocked and drive the damping rod to correspondingly descend to the cavity inner wall, and the elasticity of the spring will quickly reset the protruding block and the soft block, so that the shell and the shielding layer will not damage the support layer and affect the recovery of bone tissue. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 A perspective view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0025] Figure 2 A front view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0026] Figure 3 A partial structure detail view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0027] Figure 4 A partial structure explosion view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0028] Figure 5 A buffer mechanism split view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0029] Figure 6 A partial structure schematic view of a composite scaffold for bone tissue engineering is provided for the utility model;

[0030] Figure 7 A partial structure split view of a composite scaffold for bone tissue engineering is provided for the utility model.

[0031] LEGEND:

[0032] 1, housing; 2, buffer mechanism; 201, soft block; 202, protruding block; 203, damping rod; 204, spring; 205, cavity; 206, connecting block; 3, connecting piece; 4, shielding layer; 5, sealing ring; 6, medicine outlet hole I; 7, support layer; 8, mounting block; 9, fixed rod; 10, connecting rod; 11, cavity I; 12, filter screen; 13, fixed ring; 14, connecting pipe; 15, groove; 16, cavity II; 17, fixed block; 18, medicine outlet hole II; 19, bottom plate; 20, knob; 21, rotating shaft; 22, cross brace; 23, clamping block; 24, rack; 25, sliding groove; 26, clamping groove; 27, gear. DETAILED DESCRIPTION

[0033] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0034] Embodiment one:

[0035] Reference Figure 1 , Figure 3 and Figure 4The utility model provides an embodiment: a kind of composite scaffold for bone tissue engineering, including shell 1, the inner side of shell 1 is fixedly connected with shielding layer 4, the inner side of shielding layer 4 is installed with support layer 7, the outer wall of support layer 7 is installed with multiple fixed rings 13 at equal intervals, the outer wall middle part of fixed ring 13 is installed with filter screen 12, the bottom of fixed ring 13 is fixedly connected with fixed block 17, the bottom of fixed block 17 is fixedly connected with bottom plate 19, the top end of bottom plate 19 is fixedly connected with connecting pipe 14, the top wall of bottom plate 19 is opened with multiple medicine outlet holes two 18 at equal intervals, the middle part of fixed block 17 and connecting pipe 14 is provided with cavity two 16, the outer wall of connecting pipe 14 is opened with multiple grooves 15 at equal intervals, the middle part of shielding layer 4 and support layer 7 is provided with cavity one 11, the front and rear ends of cavity one 11 are installed with sealing ring 5, sealing ring 5 is sealed to cavity one 11, prevents internal medicine from leaking in large quantities, influence treatment effect, the outer wall of sealing ring 5 is opened with multiple medicine outlet holes one 6 at equal intervals, cavity one 11 can fill medicine of anti-inflammatory, analgesic, anti-infection and promoting cartilage growth, filter screen 12 is convenient for medicine to enter connecting pipe 14, after medicine enters connecting pipe 14, it is then from groove 15 and flows into the region of adjacent cavity two 16, then medicine is guided to support layer 7 and bone contact area by medicine outlet hole two 18, can effectively promote bone tissue cell to grow smoothly and quickly, repair damaged bone tissue, the outer wall rear side of shell 1 is fixedly connected with multiple connecting pieces 3 at equal intervals, the middle part of connecting piece 3 is rotatably connected with connecting rod 10, the inner wall of shielding layer 4 is installed with multiple buffering mechanisms 2 at equal intervals, buffering mechanism 2 is used to reduce the influence of vibration to fracture area, the front side of the outer wall of shell 1 is fixedly connected with mounting block 8, the outer wall right side of mounting block 8 is installed with knob 20, the end of knob 20 is fixedly connected with shaft 21, the end of shaft 21 is fixedly connected with gear 27, rotates knob 20, knob 20 transmission shaft 21 drives gear 27 to rotate;

[0036] Specifically, cavity one 11 can fill medicine of anti-inflammatory, analgesic, anti-infection and promoting cartilage growth, filter screen 12 is convenient for medicine to enter connecting pipe 14, after medicine enters connecting pipe 14, it is then from groove 15 and flows into the region of adjacent cavity two 16, then medicine is guided to support layer 7 and bone contact area by medicine outlet hole two 18, can effectively promote bone tissue cell to grow smoothly and quickly, repair damaged bone tissue.

[0037] Embodiment two:

[0038] Refer to Figure 2 、 Figure 5 and Figure 6The buffering mechanism 2 comprises a connecting block 206 which is equidistantly arranged on the inner wall of the shielding layer 4, a cavity 205 is arranged on the inner wall of the connecting block 206, a damping rod 203 is arranged on the inner bottom wall of the cavity 205, a spring 204 is arranged on the outer wall of the damping rod 203, a protruding block 202 is fixedly connected to the end of the damping rod 203, a soft block 201 is fixedly connected to the top of the protruding block 202, the spring 204 can rebound quickly under extrusion, and the soft block 201 is reset, when the shell 1 and the shielding layer 4 collide with the supporting layer 7, the soft block 201 touches the supporting layer 7, the soft block 201 is blocked and drives the damping rod 203 to correspondingly descend to the inner wall of the cavity 205, and the spring 204 is reset quickly to lift the protruding block 202 and the soft block 201, so that the shell 1 and the shielding layer 4 cannot damage the supporting layer 7 and affect the recovery of bone tissue, the outer wall of the rotating shaft 21 is provided with a cross brace 22, the cross brace 22 is fixedly connected to the inner wall of the top of the mounting block 8, the left side of the gear 27 is provided with a clamping block 23, and a sliding groove 25 is arranged in the middle of the clamping block 23.

[0039] Specifically, when the shell 1 and the shielding layer 4 collide with the supporting layer 7, the soft block 201 touches the supporting layer 7, the soft block 201 is blocked and drives the damping rod 203 to correspondingly descend to the inner wall of the cavity 205, and the spring 204 is reset quickly to lift the protruding block 202 and the soft block 201, so that the shell 1 and the shielding layer 4 cannot damage the supporting layer 7 and affect the recovery of bone tissue.

[0040] Example three:

[0041] With reference to Figure 1 , Figure 2 and Figure 7 , the inner wall of the mounting block 8 is provided with a fixed rod 9, a plurality of clamping grooves 26 are equidistantly arranged on the outer wall of the fixed rod 9, the left side of the gear 27 is engaged with a rack 24, the rack 24 is slidingly connected to the inner wall of the sliding groove 25, and the gear 27 rotates to drive the rack 24 to slide on the inner wall of the sliding groove 25.

[0042] Specifically, the shell 1 is closed, the fixed rod 9 is inserted into the inner side of the mounting block 8, and then the knob 20 is rotated, so that the rack 24 enters the clamping groove 26 and is clamped, thereby forming a stable connection.

[0043] Working principle: the cavity one 11 can be filled with drugs for anti-inflammatory, analgesic, anti-infective and promotion of cartilage growth, the filter screen 12 facilitates the drugs to enter the connecting pipe 14, the drugs enter the connecting pipe 14 and then flow into the adjacent cavity two 16 area from the groove 15, and then the drugs are guided to the contact area between the supporting layer 7 and the bone through the medicine outlet hole two 18, so as to effectively promote the smooth and rapid growth of bone tissue cells and repair damaged bone tissue.

[0044] When the shell 1 and the shielding layer 4 collide with the support layer 7 when vibrating, the soft block 201 touches the support layer 7, the soft block 201 is blocked to drive the damping rod 203 to correspondingly descend to the inner wall of the cavity 205, and the elasticity of the spring 204 is quickly reset to lift the convex block 202 and the soft block 201, so that the shell 1 and the shielding layer 4 do not cause damage to the support layer 7, and affect the recovery of bone tissue.

[0045] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application have been described in detail, for those skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, within the spirit and principles of the present application, any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.

Claims

1. A composite scaffold for bone tissue engineering comprising an outer shell (1) characterised in that: The inner side of the shell (1) is fixedly connected with a shielding layer (4), the inner side of the shielding layer (4) is mounted with a supporting layer (7), the outer wall of the supporting layer (7) is equidistantly mounted with a plurality of fixed rings (13), the middle part of the outer wall of the fixed ring (13) is mounted with a filter screen (12), the bottom end of the fixed ring (13) is fixedly connected with a fixed block (17), the bottom end of the fixed block (17) is fixedly connected with a bottom plate (19), the top end of the bottom plate (19) is fixedly connected with a connecting pipe (14), the top wall of the bottom plate (19) is equidistantly provided with a plurality of medicine outlet holes (18), the middle part of the fixed block (17) and the connecting pipe (14) is provided with a cavity (16), the outer wall of the connecting pipe (14) is equidistantly provided with a plurality of grooves (15), the middle part of the shielding layer (4) and the supporting layer (7) is provided with a cavity (11), the front and rear ends of the cavity (11) are mounted with a sealing ring (5), the outer wall of the sealing ring (5) is equidistantly provided with a plurality of medicine outlet holes (6), the outer wall of the shell (1) is equidistantly fixedly connected with a plurality of connecting pieces (3), the middle part of the connecting piece (3) is rotatably connected with a connecting rod (10), the inner wall of the shielding layer (4) is equidistantly mounted with a plurality of buffering mechanisms (2), and the buffering mechanism (2) is used to reduce the influence of vibration on the fracture area.

2. The composite scaffold for bone tissue engineering according to claim 1, wherein: The buffering mechanism (2) comprises a connecting block (206), the connecting block (206) is equidistantly mounted on the inner wall of the shielding layer (4), the inner side of the connecting block (206) is provided with a cavity (205), the inner bottom wall of the cavity (205) is mounted with a damping rod (203), the outer wall of the damping rod (203) is mounted with a spring (204), the end of the damping rod (203) is fixedly connected with a protruding block (202), and the top end of the protruding block (202) is fixedly connected with a soft block (201).

3. The composite scaffold for bone tissue engineering according to claim 1, wherein: The outer wall of the shell (1) is fixedly connected with a mounting block (8), and the outer wall of the mounting block (8) is mounted with a knob (20).

4. The composite scaffold for bone tissue engineering according to claim 3, wherein: The end of the knob (20) is fixedly connected with a rotating shaft (21), and the end of the rotating shaft (21) is fixedly connected with a gear (27).

5. The composite scaffold for bone tissue engineering according to claim 4, wherein: The outer wall of the rotating shaft (21) is mounted with a cross brace (22), and the cross brace (22) is fixedly connected to the inner wall top of the mounting block (8).

6. The composite scaffold for bone tissue engineering according to claim 4, wherein: The left side of the gear (27) is mounted with a clamping block (23), and the middle part of the clamping block (23) is provided with a sliding groove (25).

7. The composite scaffold for bone tissue engineering according to claim 3, wherein: The inner wall of the mounting block (8) is provided with a fixed rod (9), and the outer wall of the fixed rod (9) is equidistantly provided with a plurality of clamping grooves (26).

8. The composite scaffold for bone tissue engineering according to claim 4, wherein: The left side of the gear (27) is engagedly connected with a rack (24), and the rack (24) is slidingly connected to the inner wall of the sliding groove (25).

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