Sampling device for biopharmaceutical production
By designing a sampling device for biopharmaceutical production, and utilizing a telescopic column and a rotating disk with a staggered sealing structure, the problem of difficult raw material sampling deep within the fermenter was solved, achieving efficient and low-pollution sampling results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-22
- Publication Date
- 2026-03-27
AI Technical Summary
Existing biopharmaceutical fermenters cannot effectively sample raw materials at deeper locations within the tank, resulting in sampling tools contaminating the raw materials and being inconvenient to operate.
Design a sampling device for biopharmaceutical production, comprising a main body, a telescopic column, a rocker arm, a sampling mechanism, a fixed rod, a rotating rod, and a rotating disk. The rocker arm drives the rotating disk to perform staggered sealing, thereby achieving sampling of raw materials inside the fermenter.
This method enables effective sampling of raw materials inside the fermenter, reduces the risk of contamination, and improves the convenience of sampling operations.
Smart Images

Figure CN224051659U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to sampling device technical field, specifically is a kind of sampling device for biological pharmaceutical production. BACKGROUND
[0002] Biopharmaceutical raw materials are mainly natural biological materials, including microorganisms, animals, plants, marine organisms, etc. Currently, most of the drugs in biopharmaceuticals contain organic components, which need to be obtained through microbial fermentation. In order to control the progress of pharmaceutical production during the fermentation process, sampling is required to determine the progress of pharmaceutical production.
[0003] In the prior art, the sampling ports of most fermentation tanks are arranged at different positions of the tank body to facilitate sampling and detection of the inside of the tank body. However, due to the large space inside the tank body, most existing sampling tools cannot sample and detect the raw materials at a deeper position of the tank body during use. Instead, the sampling hole needs to be replaced to sample the raw materials inside the tank body, which not only easily contaminates the raw materials but also causes many inconveniences in sampling work. SUMMARY
[0004] Therefore, the utility model aims to provide a sampling device for biological pharmaceutical production to solve the technical problem that the raw materials at a deeper position of the tank body cannot be sampled and detected, and the sampling hole needs to be replaced to sample the raw materials inside the tank body.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a sampling device for biological pharmaceutical production, comprising a main body, a telescopic column arranged inside the main body, a rocker arranged inside the telescopic column, a sampling mechanism fixedly connected to the bottom end of the telescopic column, a connecting mechanism fixedly connected to the bottom end of the rocker, a fixed rod arranged inside the connecting mechanism, a limit block fixedly connected to the top end of the fixed rod, a rotating rod arranged outside the fixed rod, a through hole matched with the fixed rod arranged inside the rotating rod, a fixed disc fixedly connected to the bottom end of the fixed rod, a rotating disc fixedly connected to the bottom end of the rotating rod, and a sampling hole matched with each other arranged inside the fixed disc and the rotating disc.
[0006] By adopting the above-mentioned technical scheme, the raw materials are collected into the cavity inside the sampling mechanism through the sampling hole after the sampling mechanism is inserted into the fermentation tank, and then the rotating disc is rotated by the rocker, so that the sampling holes arranged inside the rotating disc and the fixed disc are dislocated, the cavity inside the sampling mechanism is sealed, and the raw materials inside the fermentation tank are taken out.
[0007] Further, a sealing plate is fixedly connected inside the sampling mechanism, a through hole matched with the rotating rod is arranged inside the sealing plate, and a cavity is arranged between the fixed disc and the sealing plate.
[0008] By adopting the technical scheme, the cavity in the sampling mechanism is divided and sealed by the structure that the sealing plate is fixedly connected to the sampling mechanism and the cavity is arranged between the fixing disc and the sealing plate.
[0009] Further, the outer wall of the main body is fixedly connected with a limiting disc, the bottom end of the limiting disc is provided with a rubber pad, and the top end of the limiting disc is provided with a handle matched with the telescopic column.
[0010] By adopting the technical scheme, the cavity in the sampling mechanism is divided and sealed by the structure that the sealing plate is fixedly connected to the sampling mechanism and the cavity is arranged between the fixing disc and the sealing plate.
[0011] Further, the limiting blocks are fixedly connected to the inner wall of the sampling mechanism at both ends, and the connecting mechanism is internally provided with a limiting slot matched with the limiting blocks.
[0012] By adopting the technical scheme, the cavity in the sampling mechanism is divided and sealed by the structure that the sealing plate is fixedly connected to the sampling mechanism and the cavity is arranged between the fixing disc and the sealing plate.
[0013] Further, the top end of the rotating rod is fixedly connected with a gear, and the connecting mechanism is internally provided with a gear slot matched with the gear.
[0014] By adopting the technical scheme, the cavity in the sampling mechanism is divided and sealed by the structure that the sealing plate is fixedly connected to the sampling mechanism and the cavity is arranged between the fixing disc and the sealing plate.
[0015] In summary, the utility model mainly has the following beneficial effects: the utility model discloses the structure that the telescopic column, the rocker and the sampling mechanism are arranged in the main body and are matched with each other, and the whole sampling effect is achieved, so that the sampling distance is increased, and meanwhile, the connecting mechanism, the fixed rod, the limiting block and the rotating rod are arranged in the sampling mechanism, and the fixing disc, the rotating disc and the sampling hole are combined, so that the sampling effect in the fermentation tank is achieved, that is, the sampling mechanism is inserted into the fermentation tank, the raw materials are collected into the cavity in the sampling mechanism through the sampling hole, then the rotating disc is rotated through the rocker, so that the sampling holes in the rotating disc and the fixing disc are staggered, the cavity in the sampling mechanism is sealed, and the raw materials in the fermentation tank are taken out. BRIEF DESCRIPTION OF DRAWINGS
[0016] Figure 1 It is the whole structure schematic view of the utility model;
[0017] Figure 2 It is the whole structure sectional view of the utility model;
[0018] Figure 3 It is the whole structure schematic view of the utility model Figure 2 The enlarged view of A of the utility model;
[0019] Figure 4 It is the partial structure schematic view of the utility model;
[0020] Figure 5 It is the partial structure schematic view of the utility model;
[0021] Figure 6 It is the internal structure schematic view of the utility model.
[0022] In the drawing: 1, main body;2, sampling mechanism;3, limit disc;4, rubber pad;5, telescopic column;6, handle;7, rocker;8, fixed disc;9, sampling hole;10, connecting mechanism;11, limit slot;12, limit block;13, rotating rod;14, fixed rod;15, rotating disc;16, through hole;17, gear;18, gear slot;19, sealing plate. DETAILED DESCRIPTION
[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. The embodiments described below with reference to the drawings are exemplary and are used only for explaining the utility model, and cannot be understood as limiting the utility model.
[0024] The embodiments of the utility model will be described below according to the whole structure of the utility model.
[0025] A kind of biological pharmaceutical production sampling device, as Figures 1-6 Shown, including main body 1, telescopic column 5 is provided in main body 1, telescopic column 5 inside is provided with rocker 7, telescopic column 5 bottom end is fixedly connected with sampling mechanism 2, rocker 7 bottom end is fixedly connected with connecting mechanism 10, connecting mechanism 10 inside is provided with fixed rod 14, fixed rod 14 top end is fixedly connected with limit block 12, fixed rod 14 outside is provided with rotating rod 13, rotating rod 13 inside is provided with through hole 16 matched with fixed rod 14, fixed rod 14 bottom end is fixedly connected with fixed disc 8, rotating rod 13 bottom end is fixedly connected with rotating disc 15, fixed disc 8 and rotating disc 15 inside are all provided with mutually matched sampling hole 9;
[0026] Specifically, the sampling mechanism is inserted into the fermentation tank, raw materials are collected into the cavity in the sampling mechanism through the sampling hole, the rotating disc is rotated by the rocker, the sampling holes in the rotating disc and the fixed disc are dislocated, the cavity in the sampling mechanism is sealed, and the raw materials in the fermentation tank are taken out.
[0027] Please refer to Figure 1 The outer wall of the main body 1 is fixedly connected with a limiting disc 3, the bottom end of the limiting disc 3 is provided with a rubber pad 4, and the top end of the limiting disc 3 is provided with a handle 6 matched with the telescopic column 5.
[0028] Please refer to Figure 4 、 Figure 5 and Figure 6 The two ends of the limiting block 12 are fixedly connected with the inner wall of the sampling mechanism 2, the connecting mechanism 10 is internally provided with a limiting slot 11 matched with the limiting block 12, the top end of the rotating rod 13 is fixedly connected with a gear 17, and the connecting mechanism 10 is internally provided with a gear groove 18 matched with the gear 17, wherein the user rotates the rocker 7, at this time, the rocker 7 drives the connecting mechanism 10 to rotate along the limiting block 12, and then the gear groove 18 arranged in the connecting mechanism 10 drives the gear 17 fixedly connected to the top end of the rotating rod 13 to rotate, thereby conveniently controlling the rotating disc 15 for the user.
[0029] The working principle of the utility model is as follows: when in use, the user holds the handle 6 and the rocker 7, inserts the main body 1 into the fermentation tank through the sampling port, at this time, the main body 1 is limited and fixed through the limiting disc 3, and the rubber pad 4 arranged at the bottom end of the limiting disc 3 can keep the fermentation tank sealed when sampling the inside of the fermentation tank.
[0030] In the use process, the user controls the telescopic column 5 to move forward and backward in the main body 1, so as to increase the sampling range of the sampling mechanism 2, when the sampling mechanism 2 is inserted into the raw materials, at this time, the raw materials enter the cavity in the sampling mechanism 2 through the through holes 16 arranged in the fixed disc 8 and the rotating disc 15, at this time, the user rotates the rocker 7, so that the through holes 16 arranged in the fixed disc 8 and the rotating disc 15 are dislocated, thereby sealing the cavity in the sampling mechanism 2.
[0031] Specifically, the user rotates the rocker 7, at this time, the rocker 7 drives the connecting mechanism 10 to rotate along the limiting block 12, and then the gear groove 18 arranged in the connecting mechanism 10 drives the gear 17 fixedly connected to the top end of the rotating rod 13 to rotate, thereby conveniently controlling the rotating disc 15 for the user.
[0032] Although the embodiments of the utility model have been shown and described, the specific embodiments are only the explanation of the utility model, and are not the limitation of the utility model, and the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable way, and the person skilled in the art can make the modification, replacement and change of the embodiments without the creative contribution after reading the specification without departing from the principles and the purpose of the utility model, but as long as in the claim range of the utility model, it is protected by the patent law.
Claims
1. A sampling device for biopharmaceutical production comprising a main body (1), characterized in that: The body (1) is internally provided with a telescopic column (5), the telescopic column (5) is internally provided with a rocker (7), the telescopic column (5) bottom end fixedly connected with a sampling mechanism (2), the rocker (7) bottom end fixedly connected with a connecting mechanism (10), the connecting mechanism (10) is internally provided with a fixed rod (14), the fixed rod (14) top end fixedly connected with a limit block (12), the fixed rod (14) outside is provided with a rotating rod (13), the rotating rod (13) is internally provided with a through hole (16) matched with the fixed rod (14).
2. The sampling device for biopharmaceutical production according to claim 1, characterized in that: The fixed rod (14) bottom end fixedly connected with a fixed disc (8), the rotating rod (13) bottom end fixedly connected with a rotating disc (15), the fixed disc (8) and rotating disc (15) are internally provided with mutually matched sampling holes (9).
3. The sampling device for biopharmaceutical production according to claim 2, characterized in that: The sampling mechanism (2) is internally fixedly connected with a sealing plate (19), the sealing plate (19) is internally provided with a through hole (16) matched with the rotating rod (13), and the fixed disc (8) and the sealing plate (19) are provided with a cavity.
4. The sampling device for biopharmaceutical production according to claim 1, characterized in that: The body (1) outer wall fixedly connected with a limit disc (3), the limit disc (3) bottom end is provided with a rubber pad (4), and the limit disc (3) top end is provided with a handle (6) matched with the telescopic column (5).
5. The sampling device for biopharmaceutical production of claim 1, wherein: The limit block (12) both ends are fixedly connected with the inner wall of the sampling mechanism (2), and the connecting mechanism (10) is internally provided with a limiting slot (11) matched with the limit block (12).
6. The sampling device for biopharmaceutical production of claim 1, wherein: The rotating rod (13) top end fixedly connected with a gear (17), the connecting mechanism (10) is internally provided with a gear slot (18) matched with the gear (17).