Material conversion device for biopharmacy

Abstract

The utility model discloses a material conversion device for biopharmacy, which comprises an outer frame and a fixed panel fixed at the upper part of the outer frame, at least two feeding pipelines are fixed on the fixed panel close to the lower position in a penetrating manner, and a plurality of external pipelines which are distributed in a fan shape by taking the center of one feeding pipeline as the circle center are fixed on the fixed panel in a penetrating manner; one end of each feeding pipeline is rotationally connected with a switching pipeline used for being communicated with any unexpected connecting pipeline, and the number of the external connecting pipelines is larger than that of the feeding pipelines. According to the utility model, through the rotary design of the transfer pipeline, external pipelines can be quickly switched, dynamic connection between multiple material sources and the reaction kettle is realized, the transfer efficiency is obviously improved, and different production requirements are met; and meanwhile, a plurality of material sources are allowed to be flexibly configured through the quantitative relation of the feeding pipelines and the external pipelines, and the complex process requirements are met.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of pharmaceutical raw material conversion, in particular to a material conversion device for biopharmaceuticals. BACKGROUND

[0002] In the biopharmaceutical production process, efficient and safe conversion of materials is one of the core process links. Traditional material conversion devices mostly use fixed pipeline connection mode, and the communication between different material sources and reaction kettles is realized by manually switching valves or manually docking pipelines. This way takes a long time to manually switch the pipeline, is difficult to adapt to the flexible needs of multi-variety and small-batch production, and is prone to material confusion due to operation errors; the pipeline interface design is complex, and residual materials are difficult to clean thoroughly, especially when frequently switching, which is prone to microbial contamination, threatening drug safety. Therefore, we provide a material conversion device for biopharmaceuticals. SUMMARY

[0003] The utility model aims at providing a material conversion device for biopharmaceuticals to solve the above problems.

[0004] The utility model can be realized through the following technical scheme: a material conversion device for biopharmaceuticals, comprising an outer frame and a fixed panel fixed to the upper part of the outer frame, at least two feed pipes are fixed through the fixed panel near the lower position, a plurality of external connection pipes are fixed through the upper position, and the center of each feed pipe is a fan-shaped distribution with one feed pipe as the center, one end of each feed pipe is rotatably connected with an adapter pipe for connecting any external connection pipe, and the number of external connection pipes is greater than that of feed pipes.

[0005] Further technical improvement of the utility model lies in that a transition pipe is arranged between the feed pipe and the adapter pipe that is not at the center of the external connection pipe distribution, and one end of the transition pipe away from the corresponding feed pipe is rotatably connected with the adapter pipe, so as to ensure that the projection of the rotation center of each adapter pipe on the fixed panel coincides.

[0006] Further technical improvement of the utility model lies in that the connection position of each pipe is installed and connected by a quick-mounting clamp.

[0007] Further technical improvement of the utility model lies in that the inlet and outlet of all pipes installed through the fixed panel are respectively in the same corresponding vertical plane.

[0008] Further technical improvement of the utility model lies in that the connection position identification of the adapter pipe and the external connection pipe is realized by electrical communication identification or on-off quantity identification.

[0009] The further technical improvement of the utility model lies in: when the electrical communication identification scheme is adopted, the read-write probe is fixedly installed on the side of the adapter pipeline close to the fixed panel, a plurality of chip labels arranged in a fan shape are uniformly installed on the fixed panel, the distance between each chip label and the center of the feed pipeline is consistent with the rotating radius of the read-write probe, and the installation position and quantity of the chip labels correspond to the external pipeline one by one.

[0010] The further technical improvement of the utility model lies in: when the switch quantity identification scheme is adopted, the probe and the physical contact are arranged on the adapter pipeline and the fixed panel respectively, and the connection position and state are identified in the contact conduction state.

[0011] The further technical improvement of the utility model lies in: the liquid receiving groove is arranged at the lower position of the fixed panel, the liquid receiving groove is fixed on the front face of the outer frame, the bottom of the liquid receiving groove is concave and the liquid outlet external joint is installed at the bottom.

[0012] The further technical improvement of the utility model lies in: for each pipeline, the height position of the cross section of any adjacent pipeline along the material flow direction continuously rises or continuously falls:

[0013] For the pipeline outlet higher than the pipeline inlet, the continuously rising is continuously falling.

[0014] For the pipeline inlet higher than the pipeline outlet, the continuously falling is continuously rising.

[0015] Compared with the prior art, the utility model has the following beneficial effects:

[0016] 1、 the utility model discloses the rotating design of adapter pipeline can quickly switch external pipeline, realizes the dynamic connection of multiple material sources and reaction kettle, remarkably promotes the material transfer efficiency, adapts to different production demands;Meanwhile, the quantity relation (M < N) of feed pipeline and external pipeline allows multiple material sources to be flexibly configured, and the complex process demand is met.

[0017] 2、 the utility model discloses the sanitary fast mounting clamp and sealing ring design are used at the pipeline connection, avoid material residue and cross contamination;Pipeline inclination design (the height of adjacent cross section continuously changes) ensures that material can be self-bleeding or backflow when there is no power, and facilitates cleaning and sterilization. DRAWINGS

[0018] In order to facilitate the understanding of those skilled in the art, the utility model will be further described below with reference to the drawings.

[0019] Figure 1 It is the overall structure front view schematic drawing of the utility model;

[0020] Figure 2 It is the overall structure left view schematic drawing of the utility model;

[0021] Figure 3 The schematic diagram of the adapter pipeline and the read-write probe is connected;

[0022] Figure 4 The utility model Figure 2 The local enlarged view of A in the middle;

[0023] Figure 5 It is the principle block diagram of electrical communication mode.

[0024] In the drawing: 1, outer frame; 2, liquid receiving groove; 3, fixed panel; 4, adapter pipeline one; 5, adapter pipeline two; 6, transition elbow; 7, feed pipeline one; 8, feed pipeline two; 9, external pipeline; 10, quick-mounting clamp; 11, chip label; 12, read-write probe. Specific implementation

[0025] In order to further explain the technical means and effects adopted by the utility model to achieve the predetermined utility model purposes, the specific implementation, structure, features and effects according to the utility model are described in detail as follows in combination with the drawings and preferred embodiments.

[0026] Please refer to Figures 1-5 As shown in the drawing, a material conversion device for biopharmaceuticals includes an outer frame 1 that can be installed and fixed on the ground, a fixed panel 3 is installed on the upper part of the outer frame 1, a liquid receiving groove 2 is arranged at the lower position of the fixed panel 3, the liquid receiving groove 2 is fixed on the front of the outer frame 1, and the bottom of the liquid receiving groove 1 is concave and is provided with a liquid outlet external joint;

[0027] The feed pipeline one 7 and the feed pipeline two 8 are fixedly penetrated on the fixed panel 3 close to the lower position, and the feed pipeline two 8 is located at the position directly below the feed pipeline one 7.

[0028] A plurality of external pipelines 9 are arranged at the upper position of the feed pipeline one 7, and in this embodiment, there are specifically 8 external pipelines 9; these external pipelines 9 are all distributed in a fan shape with the center of the feed pipeline 1 as the center, and each external pipeline 9 is fixedly penetrated on the fixed panel 3; an adapter pipeline one 4 is rotatably installed at one end of the feed pipeline one 7 located on the front of the fixed panel 3, and the other end of the adapter pipeline one 4 can be connected in communication with any one of the external pipelines 9 according to production needs.

[0029] Similarly, a transition elbow 6 is fixedly installed at one section of the feed pipeline two 8 located on the front of the fixed panel 3, the inlet and outlet directions of the transition elbow 6 are arranged at 180 degrees, the outlet position of the transition elbow 6 is coaxially arranged with the feed pipeline one 7, and an adapter pipeline two 5 is rotatably installed at the outlet end of the transition elbow 6, and the other end of the adapter pipeline two 5 can be connected in communication with any one of the external pipelines 9 according to production needs (different from the adapter pipeline one 4).

[0030] The connection between the first feeding pipe 7, the first adapter pipe 4 and the external pipe 9 is achieved by quick mounting clamp 10, and the connection between the second feeding pipe 8, the second adapter pipe 5, the transition bend pipe 6 and the external pipe 9 is also achieved by quick mounting clamp 10; the quick mounting clamp 10 is made of sanitary stainless steel, and a sealing ring is arranged at the connection position;

[0031] The first adapter pipe 4 and the second adapter pipe 5 are fixedly installed on the side close to the fixed panel 3 and are provided with reading and writing probes 12, and a plurality of chip labels 11 are arranged on the front surface of the fixed panel 3 in a fan shape; the distance between each chip label 11 and the center of the first feeding pipe 7 is consistent with the radius of rotation of the reading and writing probe 12;

[0032] It should be noted that the inlets and outlets of all the pipes installed on the fixed panel 4 are arranged in the same corresponding vertical plane; the installation position and the number of the chip labels 11 are consistent with the number of the external pipes 9.

[0033] In the embodiment, the reading and writing probes 12 are connected with I / O Link host computers, the host computers are connected with PLCs through a communication protocol to control and identify.

[0034] In other embodiments, a switching value identification scheme can also be used, that is, a physical contact and probe mode is used to define binary coding through the on-off state of the contact, so as to identify the connection state of the corresponding position.

[0035] In other embodiments, the number of the feeding pipes and the adapter pipes is not limited to two, and can be one or more; similarly, the number of the external pipes 9 is not limited to eight. The number of the feeding pipes is set as M, and the number of the external pipes 9 is set as N, and M is less than N.

[0036] When two materials need to be transferred into the reaction kettle, the two material kettles are quickly connected to the feeding pipes through the quick mounting clamp 10, the two adapter pipes are rotated, the external pipes 9 connected with the reaction kettle are connected, the two end interfaces are fastened through the quick mounting clamp 10, the valve is opened, clean compressed air is introduced into the two material kettles, the materials in the material kettles are pressed into the reaction kettle through the communication pipe structure, and the material transfer operation is completed.

[0037] It should be noted that for each pipe section, the height position of any adjacent pipe section along the material flow direction is continuously increased or decreased, so that the material can be discharged or backflowed as much as possible when there is no power, and the pipe cleaning is facilitated; specifically:

[0038] When the outlet of the pipe is higher than the inlet of the pipe along the material flow direction, the pipe is arranged in a continuously increasing mode;

[0039] When the inlet of the pipe is higher than the outlet of the pipe along the material flow direction, the pipe is arranged in a continuously decreasing mode.

[0040] The above is only a preferred embodiment of the present application, and does not limit the present application in any form. Although the present application has been disclosed as above with a preferred embodiment, it is not intended to limit the present application. Any person skilled in the art can make some changes or modifications to the above disclosed technical content to obtain equivalent embodiments with equivalent changes, without departing from the technical solution of the present application. Any simple modification, equivalent change and modification of the above embodiments made according to the technical essence of the present application still belong to the scope of the technical solution of the present application.

Claims

1. A material transfer device for biopharmaceutical use, characterized by: The application relates to a feeding device, which comprises an outer frame (1) and a fixed panel (3) fixed to the upper part of the outer frame (1), wherein at least two feeding pipes are fixedly arranged at the lower position of the fixed panel (3), a plurality of external connecting pipes (9) are fixedly arranged at the upper position of the fixed panel (3) and are distributed in a fan shape with the center of the feeding pipe as the center, one end of each feeding pipe is rotationally connected with a switching pipe for connecting any external connecting pipe (9), and the number of the external connecting pipes (9) is greater than that of the feeding pipes.

2. The material conversion device for biopharmaceuticals of claim 1, wherein, A transition elbow (6) is arranged between the feeding pipe and the switching pipe which is not located at the distribution center of the external connecting pipe (9), and the transition elbow (6) is rotationally connected with the switching pipe away from the corresponding feeding pipe, so that the projection of the rotation center of each switching pipe on the fixed panel (3) is coincident.

3. The material conversion device for biopharmaceuticals of claim 1, wherein, The connecting position of each pipe is installed and connected by using a quick mounting clamp (10).

4. The material conversion device for biopharmaceuticals of claim 1, wherein, The inlet and outlet of all the pipes installed on the fixed panel (3) are located in the same corresponding vertical plane.

5. The material conversion device for biopharmaceuticals of claim 1, wherein, The connection position identification between the switching pipe and the external connecting pipe (9) is realized by electrical communication identification or switch value identification.

6. A material conversion device for biopharmaceutical use according to claim 5, wherein When the electrical communication identification scheme is adopted, a read-write probe (12) is fixedly installed on the side of the switching pipe close to the fixed panel (3), a plurality of chip labels (11) are uniformly installed on the fixed panel (3) in a fan shape, the distance between each chip label (11) and the center of the feeding pipe (7) is consistent with the rotation radius of the read-write probe (12), and the installation position and number of the chip labels (11) are one-to-one corresponding to the external connecting pipes (9).

7. The material conversion device for biopharmaceuticals of claim 5, wherein, When the switch value identification scheme is adopted, a probe and a physical contact are arranged on the switching pipe and the fixed panel (3) respectively, and the connection position and state are identified by the conduction state of the contact.

8. The material conversion device for biopharmaceuticals of claim 1, wherein, The lower position of the fixed panel (3) is provided with a liquid receiving groove (2), the liquid receiving groove (2) is fixed to the front face of the outer frame (1), the bottom of the liquid receiving groove (2) is concave and is provided with a liquid outlet external joint.

9. The material conversion device for biopharmaceuticals of claim 1, wherein, For each section of pipe, the height position of any adjacent pipe section along the material flow direction is continuously raised or continuously lowered. For the pipe outlet being higher than the pipe inlet, the height position is continuously raised. For the pipe inlet being higher than the pipe outlet, the height position is continuously lowered.

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