Integrated virus sample nucleic acid extraction column device

Abstract

The utility model relates to an integrated virus sample nucleic acid extraction column device, which belongs to the technical field of biomedical detection and comprises an extraction tube and a collection tube, the bottom of the extraction tube is provided with a liquid outlet, the side edge of the lower end of the extraction tube is provided with a rubber abutting ring, and the inner side edge of the upper end of the collection tube is provided with a movable groove for the rubber abutting ring to movably abut. A bearing ring is arranged in the middle of the inner side of the collecting pipe, a valve plug block abuts against the bearing ring, a liquid blocking block movably plugged in the liquid outlet is arranged in the center of the top of the valve plug block, a plurality of liquid outlet holes penetrate through the valve plug block, and a liquid outlet is formed in the bottom of the collecting pipe; according to the utility model, detachable sealing connection is realized, the liquid flow direction can be accurately controlled without external power, the operation process is simplified, and the whole device has the advantages of compact structure, good sealing performance, simplicity and convenience in operation, high extraction efficiency and low cost, and is suitable for rapid nucleic acid extraction of various virus samples.

Description

TECHNICAL FIELD

[0001] The utility model relates to biomedical detection technical field, concretely relates to a kind of integrated virus sample nucleic acid extraction column device. BACKGROUND

[0002] In the field of virus detection and research, nucleic acid extraction is a key pre-step. Traditional virus sample nucleic acid extraction devices are usually composed of multiple independent components, including extraction tubes, filter columns, collection tubes, etc. Each component needs to be connected through a complex assembly process, which is tedious and time-consuming to operate, and can easily lead to sample contamination or nucleic acid loss. Existing devices generally have unreasonable structural design problems, such as inaccurate liquid flow control, reliance on external pumps or complex valve structures, which increases equipment cost and maintenance difficulty; poor sealing performance, prone to leakage during sample transfer, affecting extraction efficiency and the accuracy of test results; in addition, traditional devices are mostly split design, which occupies a large space, and is not conducive to the application of on-site rapid detection or high-throughput screening scenarios. With the development of precision medicine and instant detection technology, there is an increasing demand for devices that are easy to operate, highly integrated, well sealed, and can achieve efficient nucleic acid extraction. However, there is a lack of a nucleic acid extraction device that balances structural compactness, ease of operation, and functional reliability in the existing technology. Therefore, the utility model provides an integrated virus sample nucleic acid extraction column device to overcome the shortcomings of the prior art. SUMMARY

[0003] The utility model aims at overcoming the shortcomings of the prior art, and provides an integrated virus sample nucleic acid extraction column device.

[0004] The utility model employs the following technical scheme:

[0005] An integrated virus sample nucleic acid extraction column device includes an extraction tube and a collection tube. The extraction tube has a liquid outlet at the bottom. The lower end of the extraction tube has a rubber abutting ring. The upper end of the collection tube has a movable groove for the rubber abutting ring to abut. The inner side of the middle part of the collection tube has a receiving ring. The receiving ring has a valve plug on top. The top center of the valve plug has a liquid blocking block that moves into the liquid outlet. The valve plug has multiple liquid outlets. The bottom of the collection tube has a liquid discharge port.

[0006] Preferably, the top of the valve plug is an arc-shaped groove, and the bottom of the extraction tube is movably inserted into the arc-shaped groove.

[0007] Preferably, the top of the collection tube has a magnetic ring on the outside.

[0008] Preferably, the liquid discharge port has a liquid blocking plug.

[0009] Preferably, the pipe opening position of the extraction pipe is provided with a pressurizing plug, and a push rod is connected to the pressurizing plug.

[0010] Preferably, the outer side of the valve plug block is coated with a waterproof layer.

[0011] The utility model discloses the beneficial effect is: the utility model discloses an integrated structure design, and the extraction pipe is detachably sealed connection with the collection pipe through rubber abutment ring and movable slot, and cooperates the design of the liquid resistance block and the liquid outlet hole of valve plug block, and the liquid flow direction can be accurately controlled without external power, and the operation process is simplified. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 The utility model discloses a three-dimensional structure schematic diagram.

[0013] Figure 2 The utility model discloses an exploded view.

[0014] Figure 3 The utility model discloses the structure schematic diagram of extraction pipe.

[0015] Figure 4 The utility model discloses the structure schematic diagram of collection pipe.

[0016] Figure 5 The utility model discloses the structure schematic diagram of valve plug block. PREFERRED EMBODIMENT

[0017] The drawings are only for example explanation, and can not be understood as the limitation of the patent, and in order to better illustrate the embodiment, some components of the drawings can be omitted, enlarged or reduced, and do not represent the size of actual product, and for the technical personnel in the art, it is understandable that some well-known structure and its description in the drawings can be omitted.

[0018] As Figures 1-5As shown, an integrated virus sample nucleic acid extraction column device includes an extraction tube 001 and a collection tube 002, the extraction tube 001 is provided with a liquid outlet 110 at the bottom, and the lower end side of the extraction tube 001 is provided with a rubber abutting ring 120 made of elastic silica gel material, which has good sealing performance. The inner side of the upper end of the collection tube 002 is provided with a movable groove 220 for the movable abutment of the rubber abutting ring 120, and the two are detachably connected through interference fit to ensure the sealed connection between the extraction tube 001 and the collection tube 002. The inner side of the collection tube 002 is provided with a receiving ring 230, and the receiving ring 230 is provided with a valve plug 003. The top center of the valve plug 003 is provided with a liquid blocking block 310 which is movably inserted into the liquid outlet 110. When the extraction tube 001 is moved upward, the liquid outlet 110 at the bottom of the extraction tube 001 is separated from the liquid blocking block 310. A plurality of liquid outlet holes 320 are formed through the valve plug 003, and liquid is discharged from the liquid outlet holes 320. The bottom of the collection tube 002 is provided with a liquid outlet 240.

[0019] Further optimization of the scheme is as follows: Figures 1-5 As shown, the top of the valve plug 003 is provided with an arc-shaped groove 330, and the bottom of the extraction tube 001 is movably inserted into the arc-shaped groove 330. After the bottom of the extraction tube 001 is inserted into the groove, precise positioning is achieved through the guiding action of the arc surface.

[0020] Further optimization of the scheme is as follows: Figures 1-5 As shown, the top of the valve plug 003 is provided with an arc-shaped groove 330, and the bottom of the extraction tube 001 is movably inserted into the arc-shaped groove 330. After the bottom of the extraction tube 001 is inserted into the groove, precise positioning is achieved through the guiding action of the arc surface.

[0021] Further optimization of the scheme is as follows: Figures 1-5 As shown, the top of the valve plug 003 is provided with an arc-shaped groove 330, and the bottom of the extraction tube 001 is movably inserted into the arc-shaped groove 330. After the bottom of the extraction tube 001 is inserted into the groove, precise positioning is achieved through the guiding action of the arc surface.

[0022] Further optimization of the scheme is as follows: Figures 1-5 As shown, the top of the valve plug 003 is provided with an arc-shaped groove 330, and the bottom of the extraction tube 001 is movably inserted into the arc-shaped groove 330. After the bottom of the extraction tube 001 is inserted into the groove, precise positioning is achieved through the guiding action of the arc surface.

[0023] Further optimization of the scheme is as follows: Figures 1-5 As shown, the top of the valve plug 003 is provided with an arc-shaped groove 330, and the bottom of the extraction tube 001 is movably inserted into the arc-shaped groove 330. After the bottom of the extraction tube 001 is inserted into the groove, precise positioning is achieved through the guiding action of the arc surface.

[0024] In the drawings, the position relationship is only used for example description, and cannot be understood as the limitation of the patent; obviously, the above embodiment of the utility model is only for clearly illustrating the utility model, and is not the limitation of the embodiment of the utility model. For ordinary skilled in the art, on the basis of the above description, other different forms of changes or changes can be made. Here, it is not necessary and impossible to exhaust all the embodiments. Any modification, equivalent replacement and improvement, etc. made in the spirit and principle of the utility model should be included in the protection scope of the utility model claim.

Claims

1. An integrated viral sample nucleic acid extraction column device, characterized in that: The device includes an extraction tube (001) and a collection tube (002). The extraction tube (001) has a liquid outlet (110) at its bottom and a rubber abutment ring (120) on its lower side. The collection tube (002) has a movable groove (220) on its upper inner side for the rubber abutment ring (120) to move and abut. The collection tube (002) has a receiving ring (230) in the middle of its inner side and a valve plug (003) abutting against the receiving ring (230). The valve plug (003) has a liquid blocking block (310) at the top center that is movable and plugged into the liquid outlet (110). The valve plug (003) has multiple liquid outlet holes (320) through it. The collection tube (002) has a drain outlet (240) at its bottom.

2. The integrated viral sample nucleic acid extraction column device according to claim 1, characterized in that: The top of the valve plug (003) is provided with an arc-shaped groove (330), and the bottom of the extraction tube (001) is movably inserted into the arc-shaped groove (330).

3. The integrated viral sample nucleic acid extraction column device according to claim 1, characterized in that: A magnetic ring (004) is fitted on the outer side of the top of the collecting tube (002).

4. The integrated viral sample nucleic acid extraction column device according to claim 1, characterized in that: The drain port (240) is provided with a liquid-blocking plug (005).

5. The integrated viral sample nucleic acid extraction column device according to claim 1, characterized in that: The extraction tube (001) is provided with a pressure plug (006) at the tube opening, and a push rod (601) is connected to the pressure plug (006).

6. The integrated viral sample nucleic acid extraction column device according to claim 1, characterized in that: The outer edge of the valve plug (003) is coated with a waterproof layer (340).

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