Temperature control equipment for continuous crystallization of tilpotide

Abstract

The utility model relates to the technical field of pharmaceutical equipment, in particular to continuous crystallization temperature control equipment for tilpotide. According to the technical scheme, the temperature control device comprises a temperature control machine and further comprises a rotating groove formed in the top of the temperature control machine, and an oil filling port is formed in the inner bottom wall of the rotating groove; the refueling funnel is rotationally connected into the rotating groove; the rotating rod is fixedly connected to the outer wall of the middle of the oil filling funnel, and a rotating groove is formed in the temperature control machine. Through cooperation of the rotating groove, the oil filling port, the oil filling funnel, the rotating groove, the rebounding mechanism, the anti-reversion mechanism and other structures, the temperature controller and the oil filling funnel are integrally designed, during oil filling, an oil inlet of the oil filling funnel can be rotated to be overlapped and communicated with the oil filling port, and the funnel does not need to be additionally taken and placed; after use, the anti-reversion mechanism is opened, and the rebound mechanism automatically resets to close the funnel, so that residual oil is prevented from being exposed, the cleaning requirement is reduced, and the problems of cleaning, pollution and equipment operation risks caused by the use of additional refueling equipment are solved from the source.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical equipment technology, and in particular to a temperature control device for continuous crystallization of telpopeptide. Background Technology

[0002] Telpopotetine is a novel hypoglycemic drug. The temperature control equipment commonly used for continuous crystallization of Telpopotetine is an integrated refrigeration and heating unit, also known as a high-low temperature integrated unit. Traditional high-low temperature integrated units have a top-mounted oil filling port. To ensure a good seal, prevent oil leakage and the intrusion of external substances, maintain a stable internal environment, and ensure performance and safety, a small interface for adding heat transfer oil is usually provided. In existing technology, the oil filling port requires the use of a funnel. This method necessitates cleaning the funnel after filling; otherwise, residual oil will clog the funnel and interfere with subsequent fillings. Improper cleaning can also contaminate the oil, thus affecting the normal operation of the equipment. Utility Model Content

[0003] The purpose of this invention is to address the problem in the existing technology that the top oil filling port of the high and low temperature integrated machine requires the use of a funnel to add heat transfer oil, and the funnel needs to be cleaned after oiling, otherwise it is easy to clog and interfere with the next oiling. Improper cleaning will also contaminate the oil and affect the operation of the equipment. The invention proposes a continuous crystallization temperature control device for telpoeptide.

[0004] The technical solution of this utility model is as follows: A temperature control device for continuous crystallization of telpoide, comprising a temperature controller, and further comprising: a rotating groove formed on the top of the temperature controller, wherein an oil filling port is formed on the inner bottom wall of the rotating groove; an oil filling funnel rotatably connected to the rotating groove; a rotating rod fixedly connected to the outer wall of the middle part of the oil filling funnel; a rotating groove formed inside the temperature controller, wherein a spring-loaded mechanism is provided inside the rotating groove to drive the rotating rod to return to its original position after rotation; and an anti-reverse mechanism installed on the outer wall of the temperature controller to lock the spring-loaded mechanism to return to its original position.

[0005] Optionally, the rebound mechanism includes a baffle fixedly connected inside the rotating groove, a fixing plate fixedly connected to the outer wall of the rotating rod, and a first spring provided inside the rotating groove, one end of the first spring being fixedly connected to the baffle and the other end of the first spring being fixedly connected to the fixing plate.

[0006] Optionally, the anti-reverse mechanism includes a support fixedly connected to the outer wall of the temperature controller, a gear fixedly connected to the end of the rotating rod away from the oiling funnel that movably passes through the temperature controller, a support rod fixedly connected to the support, a sleeve movably sleeved on the support rod, a locking rod for locking the gear fixedly connected to the outer wall of the sleeve, a second spring sleeved inside the sleeve and connected to the support rod, a locking head fixedly connected to the end of the support rod away from the support, one end of the second spring fixedly connected to the locking head, and the other end of the second spring fixedly connected to the inner wall of the sleeve.

[0007] Optionally, a retaining ring is fixedly fitted at the end of the sleeve away from the support.

[0008] Optionally, the refueling funnel has an oil inlet that overlaps with and communicates with the refueling port.

[0009] Optionally, the top of the rotating groove is provided with a slot, and the end of the refueling funnel is provided with a corresponding groove.

[0010] Optionally, a limiting plate that holds the refueling funnel is fixedly connected to the upper surface of the temperature controller.

[0011] Optionally, the inside of the refueling funnel is fixedly connected with an oil-blocking protrusion.

[0012] In summary, this application includes at least one of the following beneficial technical effects:

[0013] This invention utilizes a combination of a rotating trough, a filling port, a filling funnel, a rotating trough, a spring mechanism, and an anti-reverse mechanism to integrate the temperature controller with the filling funnel. During filling, the oil inlet of the filling funnel can be rotated to coincide with and connect with the filling port, eliminating the need for additional funnel removal and placement. After use, opening the anti-reverse mechanism automatically resets the spring mechanism to close the funnel, preventing residual oil exposure and reducing cleaning requirements. This fundamentally solves the cleaning, pollution, and equipment operation risks caused by using additional filling equipment. Attached Figure Description

[0014] Figure 1 A schematic diagram of the structure of a continuous crystallization temperature control device for telpoide according to this utility model is provided;

[0015] Figure 2 for Figure 1 A schematic diagram of the cross-sectional structure;

[0016] Figure 3 for Figure 2 Enlarged view of point A in the middle;

[0017] Figure 4 for Figure 2 A schematic diagram of the split structure;

[0018] Figure 5 for Figure 4 Enlarged view of point B in the middle;

[0019] Figure 6 for Figure 4 Partial structural diagram;

[0020] Figure 7 for Figure 6 A partial cross-sectional structural diagram.

[0021] Reference numerals in the attached diagram: 1. Temperature controller; 11. Limiting plate; 12. Rotating groove; 13. Oil filling port; 14. Slot; 15. Rotating groove; 16. Baffle; 2. Oil filling funnel; 21. Oil inlet; 22. Clip groove; 23. Rotating rod; 24. Fixing plate; 25. First spring; 26. Gear; 201. Oil blocking protrusion; 3. Support; 31. Support rod; 32. Clamp head; 33. Sleeve; 34. Clamping ring; 35. Clamping rod; 36. Second spring. Detailed Implementation

[0022] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of this utility model, but not all embodiments.

[0023] The components of the present invention embodiments described and shown in the accompanying drawings can typically be arranged and designed in a variety of different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention.

[0024] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0025] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0026] It should be noted that the terms "comprising," "including," or any other variations thereof are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. In this specification, illustrative expressions of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0027] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0028] Example

[0029] like Figures 1 to 7 As shown, the present invention discloses a temperature-controlled device for continuous crystallization of telpoide, comprising a temperature controller 1, a rotating groove 12 at the top of the temperature controller 1, and an oil filling port 13 on the inner bottom wall of the rotating groove 12, the diameter of which is the same as that of the oil inlet 21; an oil filling funnel 2 is rotatably connected inside the rotating groove 12, and the outer wall of the oil filling funnel 2 is provided with rubber gaskets to increase the sealing performance by ensuring contact between the outer wall of the oil filling funnel 2 and the inner wall of the rotating groove 12. An oil inlet 21 is provided on the oil filling funnel 2, which overlaps with and communicates with the oil filling port 13; a rotating rod 23 is fixedly connected to the outer wall of the middle part of the oil filling funnel 2; and a rotating groove 15 is provided inside the temperature controller 1.

[0030] Among them, such as Figure 5 and Figure 6 As shown, the rotating groove 15 is equipped with a spring-loaded mechanism inside to restore the rotating rod 23 to its original position after rotation. The spring-loaded mechanism includes a baffle 16 fixedly connected inside the rotating groove 15, and a fixing plate 24 fixedly connected to the outer wall of the rotating rod 23. The rotating groove 15 is also equipped with a first spring 25, which causes the refueling funnel 2 to automatically return to its original position after rotation. One end of the first spring 25 is fixedly connected to the baffle 16, and the other end of the first spring 25 is fixedly connected to the fixing plate 24.

[0031] In addition, such as Figures 3 to 7As shown, the outer wall of the temperature controller 1 is equipped with an anti-reverse mechanism that prevents the spring-loaded mechanism from returning to its original position. The anti-reverse mechanism includes a support 3 fixedly connected to the outer wall of the temperature controller 1. A gear 26 is fixedly connected to the end of a rotating rod 23 that is away from the oiling funnel 2, passing through the temperature controller 1. A support rod 31 is fixedly connected to the support 31, and a sleeve 33 is movably fitted onto the support rod 31. A locking rod 35 is fixedly connected to the outer wall of the sleeve 33 to lock the gear 26. The locking rod 35 is designed so that the gear 26 can only rotate in one direction; when rotating in the other direction, it will be automatically locked by the end of the locking rod 35. Inside the sleeve 33 is a second spring 36 that engages with the support rod 31. The second spring 36 causes the locking rod 35 to rotate automatically after being pressed against by the rotating gear 26. When the rotating gear 26 rotates in the other direction, it will be automatically locked by the end of the locking rod 35. A clamp 32 is fixedly connected to the end of the support rod 31 away from the support 3. The clamp 32 clamps the end of the sleeve 33. After the end of the sleeve 33 slides along the support rod 31 and abuts against the clamp 32, the clamp rod 35 will disengage from the clamped rotating gear 26. One end of the second spring 36 is fixedly connected to the clamp 32, and the other end of the second spring 36 is fixedly connected to the inner wall of the sleeve 33.

[0032] It is worth noting that, such as Figure 3 and Figure 7 As shown, a retaining ring 34 is fixedly fitted at the end of the sleeve 33 away from the support 3. The retaining ring 34 facilitates the manual pulling of the end of the sleeve 33, ensuring that the manual operation of the sleeve 33 is convenient and labor-saving.

[0033] Furthermore, such as Figure 3 and Figure 6 As shown, the top of the rotating groove 12 has a slot 14, which is convenient for manually inserting the slot 14 into the buckle slot 22. The end of the refueling funnel 2 has a buckle slot 22 corresponding to the slot 14, which is convenient for rotating the refueling funnel 2 after being manually inserted into the buckle slot 22.

[0034] Furthermore, such as Figures 2 to 3 As shown, a limiting plate 11 is fixedly connected to the upper surface of the temperature controller 1 to hold the oiling funnel 2. The limiting plate 11 allows the oiling funnel 2 to be opened for easy oiling, and closed for a tight connection with the rotating groove 12, preventing dust from entering the oiling funnel 2. An oil-blocking protrusion 201 is fixedly connected inside the oiling funnel 2. The oil-blocking protrusion 201 blocks the oil remaining in the opening end of the oiling funnel 2 after it is rotated closed, preventing it from flowing into the rotating groove 12.

[0035] In this embodiment, when using a continuous crystallization temperature control device for telpoide, such as... Figure 3 As shown, simply insert your hand into the slot 14 and firmly engage it in the buckle slot 22. First, move the end of the refueling funnel 2 upwards to allow it to rotate within the rotating groove 12. Continue rotating the refueling funnel 2 within the rotating groove 12 until... Figure 3In the indicated state, the filling funnel 2 firmly abuts against one end of the limiting plate 11, and the oil inlet 21 overlaps and connects with the filling port 13. Simultaneously, the rotation of the filling funnel 2 causes the rotating rod 23 to rotate, which in turn drives the gear 26 at its end to rotate. When the gear 26 rotates in the reverse direction, it is tightly locked by the end of the locking rod 35, preventing the gear 26 from rotating in the reverse direction, thus keeping the filling funnel 2 in a position... Figure 3 Avoid closing the shown state, and finally, you can easily add oil to the filling port 13 by using the same principle as the filling funnel 2.

[0036] After the refueling funnel 2 is used, simply pull the retaining ring 34 away from the temperature controller 1. The retaining ring 34 will then disengage the sleeve 33 and the retaining rod 35 from the gear 26. At this point, the retaining rod 35 can no longer hold the gear 26. Furthermore, the rotation of the rotating rod 23 causes the fixing plate 24 to rotate, which in turn stretches the first spring 25. When the refueling funnel 2 is no longer held, the elastic rebound force of the first spring 25 will cause the fixing plate 24 to sequentially move the rotating rod 23 and the refueling funnel 2 back to their original positions. Figure 1 As shown, the oil inlet 21 and the filling port 13 are ultimately staggered, which causes the outer wall of the filling funnel 2 to tightly lock the oil inlet 21, thus not only closing the filling port 13, but also closing the filling funnel 2 within the rotating groove 12.

[0037] The preferred embodiments of this utility model described above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to any specific implementation. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A temperature-controlled device for continuous crystallization of telpoide, comprising a temperature controller (1), characterized in that, Also includes: A rotating groove (12) is provided on the top of the temperature controller (1), and an oil filling port (13) is provided on the inner bottom wall of the rotating groove (12); Rotate the oiling funnel (2) connected in the rotating groove (12); A rotating rod (23) is fixedly connected to the outer wall of the middle part of the refueling funnel (2). The temperature controller (1) has a rotating groove (15) inside. The rotating groove (15) has a spring mechanism inside that drives the rotating rod (23) to return to its original position after rotation. An anti-reverse mechanism is installed on the outer wall of the temperature controller (1) to lock the spring mechanism and restore it to its original position.

2. A temperature-controlled apparatus for continuous crystallization of telopeptides according to claim 1, characterized in that, The rebound mechanism includes a baffle (16) fixedly connected inside the rotating groove (15), a fixing plate (24) fixedly connected to the outer wall of the rotating rod (23), and a first spring (25) is also provided inside the rotating groove (15). One end of the first spring (25) is fixedly connected to the baffle (16), and the other end of the first spring (25) is fixedly connected to the fixing plate (24).

3. A temperature-controlled apparatus for continuous crystallization of telopeptides according to claim 1, characterized in that, The anti-reverse mechanism includes a support (3) fixedly connected to the outer wall of the temperature controller (1), a gear (26) fixedly connected to the end of the rotating rod (23) away from the oiling funnel (2) after passing through the temperature controller (1), a support rod (31) fixedly connected to the support (3), a sleeve (33) movably sleeved on the support rod (31), a locking rod (35) that locks the gear (26) fixedly connected to the outer wall of the sleeve (33), a second spring (36) that is sleeved with the support rod (31) is provided inside the sleeve (33), a locking head (32) is fixedly connected to the end of the support rod (31) away from the support (3), one end of the second spring (36) is fixedly connected to the locking head (32), and the other end of the second spring (36) is fixedly connected to the inner wall of the sleeve (33).

4. A temperature-controlled apparatus for the continuous crystallization of telopeptides according to claim 3, characterized in that A retaining ring (34) is fixedly fitted at the end of the sleeve (33) away from the support (3).

5. A temperature-controlled apparatus for continuous crystallization of telopeptides according to claim 1, characterized in that, The refueling funnel (2) has an oil inlet (21) that overlaps with and communicates with the refueling port (13).

6. A temperature-controlled apparatus for the continuous crystallization of telopeptides according to claim 1, characterized in that, The top of the rotating groove (12) is provided with a slot (14), and the end of the refueling funnel (2) is provided with a snap groove (22) corresponding to the slot (14).

7. A temperature-controlled apparatus for continuous crystallization of telopeptides according to claim 1, characterized in that, The upper surface of the temperature controller (1) is fixedly connected to a limiting plate (11) that holds the oiling funnel (2).

8. The temperature-controlled equipment for continuous crystallization of telpoide according to claim 1, characterized in that, The inside of the refueling funnel (2) is fixedly connected with an oil-blocking protrusion (201).

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