CRRT equipment liquid temperature regulating system and dialysis system

Abstract

The utility model discloses a liquid temperature adjusting system of CRRT equipment. The liquid temperature adjusting system comprises a first-stage temperature adjusting unit and a second-stage temperature adjusting unit, the first-stage temperature adjusting unit comprises a first-stage container, a first-stage temperature adjusting actuator and a first-stage flow pump, the first-stage container is used for containing a liquid bag, and the first-stage temperature adjusting actuator is used for adjusting and controlling the temperature of liquid in the liquid bag and enabling the temperature of the liquid to be within a set preheating temperature range; the first-stage flow pump is used for pumping preheated liquid into the second-stage temperature adjusting unit according to a set flow; the second-stage temperature adjusting unit is used for conducting secondary temperature adjusting on the pumped preheated liquid, and the temperature of the liquid flowing out of the second-stage temperature adjusting unit is made to be within the set target temperature range. The utility model further discloses a dialysis system.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, specifically a liquid temperature control system and dialysis system for CRRT equipment. Background Technology

[0002] Continuous blood purification (CRRT) equipment is used for blood purification treatment of critically ill patients, with treatment times generally exceeding 8 hours and sometimes lasting for several days. The treatment process consumes a large amount of dialysate / replacement fluid. Studies have shown that patients are prone to hypothermia during treatment due to heat loss, leading to dysregulation of body temperature, which is extremely detrimental to stabilizing the patient's condition and can even result in serious consequences. Therefore, it is essential to warm the chilled or room-temperature dialysate / replacement fluid to near the patient's body temperature. Depending on the patient's condition, the target heating temperature for the treatment fluid is generally 33–39°C. The target heating temperature for the treatment fluid is set and adjusted according to the treatment prescription.

[0003] Currently, there are two main schemes for CRRT equipment's dialysate / replacement fluid. The first scheme involves the liquid in the initial liquid packaging bag (dialysis fluid / replacement fluid bag) flowing into a heated fluid bag. A container with an openable door holds the fluid bag, and heating plates on both sides heat the bag. The inside of the fluid bag has an S-shaped fluid path. The heating plates directly heat the dialysate in the bag from 5-31℃ to 37℃-38℃ (human body temperature). Temperature sensors detect the temperature of the heating plates and the temperature at the outlet of the heated fluid bag, controlling the heating plate power based on the detected temperatures. The second scheme involves the liquid in the initial liquid packaging bag (dialysis fluid / replacement fluid bag) flowing into a fluid bladder. The bladder is placed inside a semi-enclosed container with heating wires on the inner wall to heat the bladder. A metal component contacts the outer wall of the bladder to indirectly measure the temperature of the liquid inside.

[0004] Therefore, it can be seen that in the two existing main schemes, there is only one heat source providing heating and feedback control for the liquid bag / liquid bladder, and both belong to single-point heating control loops, such as... Figure 1 As shown, the liquid is heated from an initial temperature to a target temperature within a single heat source. Existing single-point heating control loops have the following shortcomings:

[0005] (1) When the temperature of the liquid is low, the heating plate will use high power to heat it. However, in the existing solution, the liquid temperature is measured by the sensor contacting the outer surface of the liquid bag, that is, the liquid temperature is measured indirectly through the liquid bag. There will be a long temperature lag time, which will cause the liquid to easily overheat, that is, the temperature of the heated liquid exceeds the target temperature.

[0006] (2) When the liquid flow rate is large, due to the limited volume of the heating container, the fresh, low-temperature liquid does not receive sufficient heat exchange, resulting in a low outlet temperature. Experimental tests showed that when the target temperature was set at 37℃, the actual heating temperature of the two CRRT models currently used in clinical practice was only 33-34℃ (room temperature 27℃). The current equipment solutions cannot solve the problems of excessively low and overheating within the nominal flow rate range of the equipment.

[0007] like Figure 6 As shown, an experimental test was conducted on the temperature loss of a commercially available model at different flow rates. At a room temperature of 16℃, the temperature of the liquid in the liquid bag was close to 16℃. The liquid pump flow rate was set to 3ml / min and 5ml / min, and the corresponding liquid temperature at the heating plate temperature was measured. The measurement results show that increasing the flow rate leads to a decrease in the actual liquid temperature at the same heating plate temperature; and the maximum flow rate of the liquid pump can be set to 100ml / min, with higher flow rates easily leading to a greater deviation in the actual liquid temperature. Utility Model Content

[0008] In view of this, the purpose of this utility model is to provide a liquid temperature control system and dialysis system for CRRT equipment, which uses a two-stage temperature control system to precisely control the liquid temperature.

[0009] To achieve the above objectives, this utility model provides the following technical solution:

[0010] This utility model first proposes a liquid temperature control system for CRRT equipment, including a primary temperature control unit and a secondary temperature control unit;

[0011] The primary temperature control unit includes a primary container, a primary temperature control actuator, and a primary flow pump. The primary container is used to hold a liquid bag, and the primary temperature control actuator is used to regulate the liquid temperature in the liquid bag and keep the liquid temperature within a set preheating temperature range. The primary flow pump is used to pump the preheated liquid into the secondary temperature control unit at a set flow rate.

[0012] The secondary temperature control unit is used to perform secondary temperature control on the preheated liquid pumped in, so that the temperature of the liquid flowing out from the secondary temperature control unit is within the set target temperature range.

[0013] Furthermore, the secondary temperature control unit uses one or more of the following methods for temperature control: heat conduction, heat radiation, or heat convection.

[0014] Furthermore, the secondary temperature control unit includes a secondary container, a secondary temperature control actuator, and a secondary flow pump. The secondary container is used to contain a liquid bladder, which is used to hold the pumped liquid. The secondary temperature control actuator is used to regulate the temperature of the liquid in the liquid bladder and keep the liquid temperature within a set target temperature range. The secondary flow pump is used to pump the temperature-controlled liquid out of the liquid bladder at a set flow rate.

[0015] Furthermore, the primary temperature control unit also includes a first temperature sensor, a second temperature sensor, and a primary temperature control control unit. The first temperature sensor is located at the outlet of the primary container or liquid bag and is used to measure the liquid temperature inside the liquid bag. The second temperature sensor is located on the primary temperature control actuator and is used to measure the temperature of the primary temperature control actuator. The primary temperature control control unit receives the temperature data measured by the first temperature sensor and the second temperature sensor and controls the output power of the primary temperature control actuator.

[0016] Furthermore, the secondary temperature control unit also includes a third temperature sensor, a fourth temperature sensor, and a secondary temperature control control unit. The third temperature sensor is located at the outlet of the secondary container or liquid bladder and is used to measure the liquid temperature inside the liquid bladder. The fourth temperature sensor is located on the secondary temperature control actuator and is used to measure the temperature of the secondary temperature control actuator. The secondary temperature control control unit receives the temperature data measured by the third and fourth temperature sensors and controls the output power of the secondary temperature control actuator.

[0017] Furthermore, it also includes a neutralization and temperature control system, which includes a neutralization container and a neutralization flow pump. The neutralization container is used to hold a neutralization liquid bag, and the neutralization flow pump is used to pump liquid from the neutralization liquid bag into the secondary temperature control unit. The pumping speed of the neutralization flow pump and the primary flow pump is controlled by the secondary temperature control unit.

[0018] Furthermore, the neutralization and temperature regulation system also includes a neutralization and temperature regulation actuator, a fifth temperature sensor, a sixth temperature sensor, and a neutralization and temperature regulation control unit. The fifth temperature sensor is used to measure the liquid temperature inside the neutralization liquid bag, the sixth temperature sensor is used to measure the temperature of the neutralization and temperature regulation actuator, and the neutralization and temperature regulation control unit receives the temperature data measured by the fifth and sixth temperature sensors and controls the heating power of the neutralization and temperature regulation actuator.

[0019] This utility model also proposes a dialysis system, including a dialyzer, wherein the dialyzer is provided with a blood inlet, a blood outlet, a dialysate inlet, and a waste liquid outlet, wherein the blood inlet is connected to an arterial line, the blood outlet is connected to a venous line, the dialysate inlet is connected to a dialysate supply system, and / or, the arterial line and / or the venous line are provided with a replacement fluid inlet, the replacement fluid inlet is connected to a replacement fluid supply system, the dialysate supply system is provided with a dialysate temperature control system, and / or, the replacement fluid supply system is provided with a replacement fluid temperature control system, wherein both the dialysate temperature control system and the replacement fluid temperature control system adopt the liquid temperature control system of the CRRT equipment as described above.

[0020] Furthermore, both the dialysate temperature control system and the replacement fluid temperature control system include a supply pipe assembly, which includes an inlet, a liquid bladder, and a pump pipe. The inlet of the supply pipe assembly is connected to the liquid bag located in the primary container, the liquid bladder is located in the secondary container, and the pump pipe corresponds one-to-one with the primary flow pump and the secondary flow pump. Both the primary flow pump and the secondary flow pump are peristaltic pumps.

[0021] Furthermore, a waste bag is connected to the dialysate outlet of the dialyzer.

[0022] Furthermore, the primary temperature control units of the dialysate temperature control system and the replacement fluid temperature control system are either integrated or separate units.

[0023] The beneficial effects of this utility model are as follows:

[0024] This utility model discloses a liquid temperature control system for CRRT equipment. It employs a two-stage temperature control unit, comprising a primary and a secondary temperature control unit. A large-capacity liquid bag is placed in the primary container, and the primary temperature control actuator regulates the temperature of the liquid within the bag, bringing the primary temperature control unit to a steady state and maintaining the liquid temperature within the bag in a preheating range close to the target temperature range. The liquid from the bag is then pumped into the secondary temperature control unit via a primary flow pump at a set flow rate for further temperature regulation, ensuring that the liquid exiting the secondary temperature control unit is within the target temperature range. Because the temperature of the liquid pumped into the secondary temperature control unit is already close to or within the target temperature range, the secondary temperature control unit can quickly reach a steady state under different flow rates, effectively preventing insufficient or overheating and precisely controlling the temperature of the liquid pumped out of the secondary container.

[0025] By setting up a neutralization and temperature control system, when the secondary temperature control unit overheats, the liquid in the neutralization bag is pumped into the secondary container by a neutralization flow pump to achieve rapid neutralization and cooling. At the same time, the secondary temperature control unit can quickly return to a steady state. In summary, the two-stage temperature control system of the CRRT equipment of this invention, by combining the secondary temperature control system and the neutralization and temperature control, can accurately control the liquid temperature. Attached Figure Description

[0026] To make the objectives, technical solutions, and beneficial effects of this utility model clearer, the following drawings are provided for illustration:

[0027] Figure 1 This is a schematic diagram of the liquid temperature control system for CRRT equipment.

[0028] Figure 2 This is a schematic diagram of the liquid temperature control system in a CRRT (Crane Reduction Reactor) device equipped with a neutralization and temperature control system.

[0029] Figure 3 This is a schematic diagram of a neutralization and temperature control system.

[0030] Figure 4 This is a schematic diagram of a dialysis system.

[0031] Figure 5 The schematic diagram is of an existing single-point heating control loop;

[0032] Figure 6 This is a graph showing the relationship between the fluid flow rate and fluid temperature of a certain model of CRRT equipment used in clinical practice.

[0033] Explanation of reference numerals in the attached figures:

[0034] 10-First-stage temperature control unit; 11-First-stage container; 12-First-stage temperature control actuator; 13-First-stage flow pump; 14-First temperature sensor; 15-Second temperature sensor; 16-First-stage temperature control unit; 17-Liquid bag;

[0035] 20-Secondary temperature control unit; 21-Secondary container; 22-Secondary temperature control actuator; 23-Secondary flow pump; 24-Third temperature sensor; 25-Fourth temperature sensor; 26-Secondary temperature control unit; 27-Liquid bladder;

[0036] 30-Dialyzer; 31-Dialysis fluid supply system; 32-Replacement fluid supply system; 33-Arterial tubing; 34-Blood pump; 35-Waste fluid pump; 36-Waste fluid bag; 37-Intravenous tubing;

[0037] 40 - Neutralization and temperature control system; 41 - Neutralization container; 42 - Neutralization flow pump; 43 - Neutralization liquid bag; 44 - Neutralization and temperature control actuator; 45 - Fifth temperature sensor; 46 - Sixth temperature sensor; 47 - Neutralization and temperature control unit. Detailed Implementation

[0038] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments are not intended to limit the present invention.

[0039] like Figure 1 As shown, the liquid temperature control system of the CRRT equipment in this embodiment includes a primary temperature control unit 10 and a secondary temperature control unit 20.

[0040] In this embodiment, the primary temperature control unit 10 includes a primary container 11, a primary temperature control actuator 12, and a primary flow pump 13. The primary container 11 is used to contain or place the liquid bag 17. The primary temperature control actuator 12 is used to regulate the liquid temperature inside the liquid bag 17 and keep the liquid temperature within a set preheating temperature range. The primary flow pump 13 is used to pump the preheated liquid into the liquid bladder 27 of the secondary temperature control unit 20 at a set flow rate. In this embodiment, the primary container 11 is a tray used to place the liquid bag 17. Of course, in other embodiments, the primary container 11 can also be a box or other structure used to store the liquid bag 17, which will not be described in detail here. The primary temperature control actuator 12 can be a common electric heating plate.

[0041] In this embodiment, the primary temperature control unit 10 further includes a first temperature sensor 14, a second temperature sensor 15, and a primary temperature control unit 16. The first temperature sensor 14 is located at the outlet of the primary container 11 or liquid bag 17 and is used to measure the liquid temperature inside the liquid bag 17. The second temperature sensor 15 is located on the primary temperature control actuator 12 and is used to measure the temperature of the primary temperature control actuator 12. The primary temperature control unit 16 receives the temperature data measured by the first temperature sensor 14 and the second temperature sensor 15, and controls the output power of the primary temperature control actuator 12 to maintain the liquid temperature inside the liquid bag 17 within a set preheating temperature range. Specifically, the primary temperature control unit 16 uses a PID feedback control method to control the output power of the primary temperature control actuator 12.

[0042] The secondary temperature control unit 20 is used to perform secondary temperature control on the preheated liquid pumped in, so that the temperature of the liquid flowing out of the secondary temperature control unit 20 is within the set target temperature range. Specifically, the secondary temperature control unit 20 can use any one or more of the following methods for temperature control: heat conduction, heat radiation, or heat convection. For example, it can use heating elements or cooling elements to heat or cool the preheated fluid in the liquid container by means of contact heat transfer, or use infrared radiation to heat the preheated fluid in the liquid container, or use hot fluid or low-temperature fluid to heat or cool the liquid container, or use low-temperature fluid to mix with the preheated fluid to adjust its temperature and achieve cooling.

[0043] In this embodiment, the secondary temperature control unit 20 includes a secondary container 21, a secondary temperature control actuator 22, and a secondary flow pump 23. The secondary container 21 is used to contain a liquid bladder 27, which is used to hold the pumped liquid. The secondary temperature control actuator 22 is used to regulate the temperature of the liquid in the liquid bladder 27 and keep the liquid temperature within a set target temperature range. The secondary flow pump 23 is used to pump the temperature-controlled liquid out of the liquid bladder 27 at a set flow rate. In this embodiment, the secondary container 21 can be a box-shaped, sleeve-shaped, or other shaped temperature control device for containing the liquid bladder 27, and the volume of the liquid bladder 27 is smaller than the liquid bag 17 used in the primary temperature control unit 10. In some embodiments, the liquid bladder 27 can also be a heated liquid bag with a volume smaller than the liquid bag 17. If the secondary temperature control unit 20 is used for secondary heating, the secondary temperature control actuator 22 can be a common electric heating plate; if the secondary temperature control unit 20 is used for cooling, the secondary temperature control actuator 22 can be a cooling device such as a semiconductor cooler.

[0044] In this embodiment, the secondary temperature control unit 20 further includes a third temperature sensor 24, a fourth temperature sensor 25, and a secondary temperature control unit 26. The third temperature sensor 24 is located at the outlet of the secondary container 21 or the liquid bladder 27 and is used to measure the liquid temperature inside the liquid bladder 27. The fourth temperature sensor 25 is located on the secondary temperature control actuator 22 and is used to measure the temperature of the secondary temperature control actuator 22. The secondary temperature control unit 26 receives the temperature data measured by the third temperature sensor 24 and the fourth temperature sensor 25 and controls the heating power of the secondary temperature control actuator 22. Specifically, the secondary temperature control unit 26 uses a PID feedback control method to control the output power of the secondary temperature control actuator 22.

[0045] In a preferred embodiment of this example, the CRRT equipment liquid temperature control system further includes a neutralization temperature control system, such as... Figure 2As shown. The neutralization and temperature control system 40 in this embodiment includes a neutralization container 41 and a neutralization flow pump 42. The neutralization container 41 is used to contain a neutralization liquid bag 43. The temperature of the liquid stored in the neutralization liquid bag 43 is lower than the maximum temperature value of the target temperature range. The inlet of the neutralization flow pump 42 is connected to the neutralization liquid bag 43, and the outlet is connected to the secondary container 21. The pumping speeds of the neutralization flow pump 42 and the primary flow pump 13 are controlled by the secondary temperature control unit 26. Specifically, when the secondary temperature control unit 20 overheats, the neutralization flow pump 42 is activated to pump the liquid in the neutralization liquid bag 43 into the secondary container 21 to achieve rapid neutralization and cooling.

[0046] In a preferred embodiment of this example, the neutralization and temperature control system 40 further includes a neutralization and temperature control actuator 44, a fifth temperature sensor 45, a sixth temperature sensor 46, and a neutralization and temperature control unit 47, such as... Figure 3 As shown. Specifically, the fifth temperature sensor 45 is used to measure the liquid temperature inside the neutralizing liquid bag 43, and the sixth temperature sensor 46 is used to measure the temperature of the neutralizing temperature control actuator 44. The neutralizing temperature control unit 47 receives the temperature data measured by the fifth and sixth temperature sensors 45 and controls the heating power of the neutralizing temperature control actuator 47 to maintain the liquid temperature inside the neutralizing liquid bag 43 within the set neutralization temperature range. Specifically, the neutralizing temperature control actuator 47 uses a PID feedback control method to control its heating power. In this way, the liquid temperature inside the neutralizing liquid bag 43 can be maintained within the set temperature range, that is, the liquid temperature inside the neutralizing liquid bag 43 is more stable, which can better neutralize and cool the secondary temperature control unit 20. In particular, the maximum temperature value of the neutralization temperature range should be lower than the maximum temperature value of the target temperature range.

[0047] The primary temperature control unit 16, the secondary temperature control unit 26, and the neutral temperature control unit 47 can be independent control units belonging to each temperature control unit, but they can communicate and regulate each other, or be regulated by the upper control module of the CRRT equipment; these three control units can also be the same control module of the CRRT equipment, which can control different temperature control units.

[0048] like Figure 4As shown, this embodiment also proposes a dialysis system, including a dialyzer 30. The dialyzer 30 is internally divided into a blood chamber and a dialysate chamber by a hollow fiber dialysis membrane. The blood chamber of the dialyzer 30 is provided with a blood inlet and a blood outlet, and the dialysate chamber is provided with a dialysate inlet and a waste fluid outlet. The blood inlet is connected to an arterial line 34, and the blood outlet is connected to a venous line 37, thereby forming an extracorporeal blood circuit. A blood pump 34 is provided on the arterial line 34. A dialysate supply system 31 is connected to the dialysate inlet of the dialyzer 30, and / or a replacement fluid inlet is provided on the arterial line 34 and / or the venous line 37. The replacement fluid inlet is connected to a replacement fluid supply system 32, which is a replacement fluid supply structure for pre-dilution, post-dilution, or mixed dilution treatment modes in clinical practice. Specifically, the dialysate supply system 31 in this embodiment is equipped with a dialysate temperature control system, and the replacement fluid supply system 32 is equipped with a replacement fluid temperature control system. Both the dialysate temperature control system and the replacement fluid temperature control system adopt the liquid temperature control system of the CRRT equipment described above in this embodiment.

[0049] Specifically, both the dialysate supply system 31 and the replacement fluid supply system 32 include a supply tubing assembly. The supply tubing assembly and the fluid bag 17 are disposable consumables, working in conjunction with the CRRT equipment's liquid temperature control system to form either a dialysate temperature control system or a replacement fluid temperature control system. The primary flow pump, secondary flow pump, and neutralization flow pump can all be peristaltic pumps. The supply tubing assembly includes an inlet, a fluid bladder 27, and pump tubing, connected by pipelines. The inlet of the supply tubing assembly is connected to the fluid bag 17 located within the primary container. The fluid bladder 27 is located within the secondary container 21. Each pump tubing corresponds to a peristaltic pump; the peristaltic pump's rotor rollers squeeze and release the pump tubing to drive the liquid flow. In this embodiment, the dialyzer 30 has a waste fluid pump 35 and a waste fluid bag 36 connected to its dialysate outlet.

[0050] Specifically, the primary temperature control units 10 of the dialysate temperature control system and the replacement fluid temperature control system can be integrated or separate. When the primary temperature control units 10 of the dialysate temperature control system and the replacement fluid temperature control system are integrated, the fluid bags of the dialysate supply system 31 and the replacement fluid supply system 32 are both placed in the same primary container and preheated simultaneously to the same preheating temperature range. Then, they are pumped into their respective independent secondary temperature control units 20 to be adjusted to the target temperature range. In this embodiment, the primary temperature control units 10 of the dialysate temperature control system and the replacement fluid temperature control system are separate. In this way, the two primary temperature control units 10 can be used to preheat and adjust the fluid bags of the dialysate supply system 31 and the replacement fluid supply system 32 to the set preheating temperature range, respectively.

[0051] Note: In this article, "and / or" refers to two logical relationships: "and" and "or". For example, "A and / or B" can mean "A or B" or "A and B".

[0052] The above-described embodiments are merely preferred embodiments provided to fully illustrate the present invention, and the scope of protection of the present invention is not limited thereto. Equivalent substitutions or modifications made by those skilled in the art based on the present invention are all within the scope of protection of the present invention. The scope of protection of the present invention is defined by the claims.

Claims

1. A liquid temperature control system for CRRT equipment, characterized in that: Includes a primary temperature control unit and a secondary temperature control unit; The primary temperature control unit includes a primary container, a primary temperature control actuator, and a primary flow pump. The primary container is used to hold a liquid bag, and the primary temperature control actuator is used to regulate the liquid temperature in the liquid bag and keep the liquid temperature within a set preheating temperature range. The primary flow pump is used to pump the preheated liquid into the secondary temperature control unit at a set flow rate. The secondary temperature control unit is used to perform secondary temperature control on the preheated liquid pumped in, so that the temperature of the liquid flowing out from the secondary temperature control unit is within the set target temperature range.

2. The liquid temperature control system for CRRT equipment according to claim 1, characterized in that: The secondary temperature control unit uses one or more of the following methods for temperature control: heat conduction, heat radiation, or heat convection.

3. The liquid temperature control system for CRRT equipment according to claim 2, characterized in that: The secondary temperature control unit includes a secondary container, a secondary temperature control actuator, and a secondary flow pump. The secondary container is used to hold a liquid bladder, which is used to hold the pumped liquid. The secondary temperature control actuator is used to regulate the temperature of the liquid in the liquid bladder and keep the liquid temperature within a set target temperature range. The secondary flow pump is used to pump the temperature-controlled liquid out of the liquid bladder at a set flow rate.

4. The liquid temperature control system for CRRT equipment according to claim 3, characterized in that: The primary temperature control unit further includes a first temperature sensor, a second temperature sensor, and a primary temperature control unit. The first temperature sensor is located at the outlet of the primary container or liquid bag and is used to measure the liquid temperature inside the liquid bag. The second temperature sensor is located on the primary temperature control actuator and is used to measure the temperature of the primary temperature control actuator. The primary temperature control unit receives the temperature data measured by the first and second temperature sensors and controls the output power of the primary temperature control actuator.

5. The liquid temperature control system for CRRT equipment according to claim 4, characterized in that: The secondary temperature control unit further includes a third temperature sensor, a fourth temperature sensor, and a secondary temperature control unit. The third temperature sensor is located at the outlet of the secondary container or liquid bladder and is used to measure the liquid temperature inside the liquid bladder. The fourth temperature sensor is located on the secondary temperature control actuator and is used to measure the temperature of the secondary temperature control actuator. The secondary temperature control unit receives the temperature data measured by the third and fourth temperature sensors and controls the output power of the secondary temperature control actuator.

6. The liquid temperature control system for CRRT equipment according to any one of claims 1-5, characterized in that: It also includes a neutralization and temperature control system, which includes a neutralization container and a neutralization flow pump. The neutralization container is used to hold a neutralization liquid bag, and the neutralization flow pump is used to pump liquid from the neutralization liquid bag into the secondary temperature control unit. The pumping speed of the neutralization flow pump and the primary flow pump is controlled by the secondary temperature control unit.

7. The liquid temperature control system for CRRT equipment according to claim 6, characterized in that: The neutralization and temperature control system also includes a neutralization and temperature control actuator, a fifth temperature sensor, a sixth temperature sensor, and a neutralization and temperature control unit. The fifth temperature sensor is used to measure the liquid temperature inside the neutralization liquid bag, the sixth temperature sensor is used to measure the temperature of the neutralization and temperature control actuator, and the neutralization and temperature control unit receives the temperature data measured by the fifth and sixth temperature sensors and controls the heating power of the neutralization and temperature control actuator.

8. A dialysis system comprising a dialyzer, the dialyzer being provided with a blood inlet, a blood outlet, a dialysate inlet, and a waste fluid outlet, wherein the blood inlet is connected to an arterial line, the blood outlet is connected to a venous line, the dialysate inlet is connected to a dialysate supply system, and / or, the arterial line and / or the venous line are provided with a replacement fluid inlet, the replacement fluid inlet being connected to a replacement fluid supply system, characterized in that: The dialysate supply system is equipped with a dialysate temperature control system, and / or the replacement fluid supply system is equipped with a replacement fluid temperature control system. Both the dialysate temperature control system and the replacement fluid temperature control system adopt the liquid temperature control system of the CRRT equipment as described in any one of claims 1-7.

9. The dialysis system according to claim 8, characterized in that: Both the dialysate temperature control system and the replacement fluid temperature control system include a supply pipe assembly. The supply pipe assembly includes an inlet, a liquid bladder, and a pump pipe. The inlet of the supply pipe assembly is connected to the liquid bag located in the primary container. The liquid bladder is located in the secondary container. The pump pipe corresponds one-to-one with the primary flow pump and the secondary flow pump. Both the primary flow pump and the secondary flow pump are peristaltic pumps.

10. The dialysis system according to claim 8 or 9, characterized in that: The primary temperature control units of the dialysis fluid temperature control system and the replacement fluid temperature control system are either integrated or separate units.

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