Liquid level detection device and exosome purification waste liquid collection equipment

Abstract

The utility model relates to a liquid level detection device and exosome purification waste liquid collection equipment, the liquid level detection device is matched with a vacuum waste liquid tank for collecting exosome purification waste liquid for use, and the liquid level detection device comprises a shielding object, a liquid level detection device, a liquid level detection device and a liquid level detection device, the shielding object can float on the liquid level of the vacuum waste liquid tank and synchronously ascends and descends along with the liquid level of the vacuum waste liquid tank; and the photoelectric assemblies are arranged outside the vacuum waste liquid tank, the two photoelectric assemblies are the first photoelectric assembly corresponding to the upper position of the vacuum waste liquid tank and the second photoelectric assembly corresponding to the lower position of the vacuum waste liquid tank, and the photoelectric assemblies and the shielding object are matched to be used for liquid level detection. The liquid level detection device adopts the scheme that the shielding object and the photoelectric component are matched to detect the liquid level, so that the influence of a complex liquid environment can be avoided, particularly the problem of bubble intermediate state interference can be avoided, the liquid level detection is more accurate, the false alarm probability is reduced, and bubbles are prevented from entering a filtrate bag.

Description

Technical Field

[0001] This utility model relates to the field of liquid level detection technology, specifically to a liquid level detection device and an exosome purification waste liquid collection device. Background Technology

[0002] During exosome purification, a disposable vacuum waste tank is used to collect the purified waste liquid. A peristaltic pump then discharges the waste liquid from the vacuum waste tank into an external filter bag. A level detection switch is installed on the vacuum waste tank to achieve precise control of the discharge. Level detection switches, based on different physical characteristics, include float-type, capacitive, ultrasonic, tuning fork-type, and photoelectric types: Float-type level detection switches mainly consist of a magnetic float, a limiting guide rod / limiting guide groove, and a reed switch. This structure is not suitable for liquids containing many impurities; the sensor needs to be in contact with the liquid or integrated into the container. Capacitive level detection switches consist of a metal rod and a metal tube, with the metal rod acting as one electrode and the metal tube as the other, forming a capacitor. This structure is susceptible to electromagnetic interference affecting measurement accuracy; the sensor also needs to be in contact with the liquid or integrated into the container. The pressure-type liquid level detection switch consists of a pressure transmitter and a reference pressure source. The pressure transmitter is installed on the bottom or side wall of the container, and the reference pressure source can be atmospheric pressure or other constant pressure sources. This sensor is susceptible to factors such as temperature, density, and viscosity. The sensor needs to be in contact with the liquid or integrated into the container. The photoelectric liquid level switch typically contains a light-emitting diode and a photoelectric sensor. It uses the principle of light transmission, scattering, and absorption in liquids or air to detect the liquid level. This detection method is susceptible to interference from liquid turbidity and air bubbles, which can cause false triggering of the photocoupler.

[0003] In a simple photoelectric detection scheme, the signal threshold received by the photoelectric element has an intermediate state. That is, assuming the signal strength of a completely blocked signal is 0 and the signal strength of an unblocked signal is 22000, the threshold for no liquid may be 12000-22000, and the threshold for liquid is 0-8000. The intermediate state (8000-12000) may be the signal threshold of foam or gas-liquid interface. However, the boundary point is not absolute. For example, the signal threshold obtained by diluted bubbles or dense bubbles in the optical path is different. It may be in a state with liquid or no liquid. It is impossible to exhaust all states for testing, so it is easy to cause false alarms.

[0004] On the other hand, vacuum waste liquid tanks used for collecting purified waste liquid usually contain many air bubbles. If a large amount of gas enters the external filter bag, it will cause problems such as bag swelling. Therefore, there is an urgent need for a liquid level detection device that can assist in the drainage of purified waste liquid tanks. Utility Model Content

[0005] The purpose of this invention is to provide a liquid level detection device and an exosome purification waste liquid collection device, which can at least partially solve the technical problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] The first aspect of this utility model discloses a liquid level detection device, which is used in conjunction with a vacuum waste liquid tank for collecting exosome purification waste liquid. The device includes a shield and a photoelectric component. The shield is disposed inside the vacuum waste liquid tank. When liquid is stored in the vacuum waste liquid tank, the shield floats on the liquid surface and rises and falls synchronously with the liquid level. The photoelectric component is disposed outside the vacuum waste liquid tank. Two sets of photoelectric components are provided: a first photoelectric component corresponding to a slightly upper position in the vacuum waste liquid tank and a second photoelectric component corresponding to a slightly lower position in the vacuum waste liquid tank. The photoelectric component and the shield work together for liquid level detection.

[0008] In a preferred embodiment, the obstruction is an opaque solid object.

[0009] In a preferred embodiment, the optoelectronic component includes a light-emitting element disposed on one side of the vacuum waste liquid tank and a photosensitive element disposed on the other side of the vacuum waste liquid tank, wherein the light-emitting element and the photosensitive element are of the same height and are disposed opposite to each other.

[0010] In a preferred embodiment, the height of the first photoelectric component is set within the range of 80%-85% of the total height of the vacuum waste liquid tank.

[0011] In a preferred embodiment, the height of the second photoelectric component is set within the range of 15%-20% of the total height of the vacuum waste liquid tank.

[0012] In a preferred embodiment, the obstruction is constructed as a rectangular structure with uniform mass.

[0013] In a preferred embodiment, the width of the obstruction is greater than 1 / 2 of the width or diameter of the vacuum waste tank.

[0014] In a preferred embodiment, the bottom of the shield is further provided with an openable counterweight cavity, in which an adjustable counterweight material is embedded.

[0015] In a preferred embodiment, the shield is made of a hydrophobic material or the surface of the shield is coated with a hydrophobic coating.

[0016] The second aspect of this utility model provides an exosome purification waste liquid collection device, including a vacuum waste liquid tank and a filter bag. The outlet end of the vacuum waste liquid tank is connected to the inlet end of the filter bag through a pipeline. The pipeline is connected to a pump body. The vacuum waste liquid tank is connected to the liquid level detection device described in the above scheme.

[0017] Compared with the prior art, the beneficial effects of this utility model are:

[0018] 1) The present invention uses a combination of obstruction and photoelectric components to detect liquid level, which can avoid the influence of complex liquid environment, especially the problem of interference from intermediate state of bubble. During detection, there are only two states: whether the light path is blocked or not, so that the liquid level detection is more accurate and the probability of false alarm is reduced.

[0019] 2) By setting two sets of photoelectric components, one above the other, and setting their height, the opening and closing time of the peristaltic pump can be precisely controlled, avoiding problems such as a large number of air bubbles entering the external filter bag during the collection of purified waste liquid, causing bag swelling.

[0020] 3) This solution adopts non-contact detection. The waste liquid tank does not integrate sensors, which can effectively extend its service life. Moreover, the internal obstructions can be replaced at low cost. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the exosome purification waste liquid collection device in an embodiment of the present invention;

[0022] Figure 2 This is a schematic diagram of the structure of the liquid level detection device and the vacuum waste liquid tank in an embodiment of the present invention;

[0023] Figure 3 This is a top view of the structure of the liquid level detection device and the vacuum waste liquid tank in an embodiment of this utility model.

[0024] The meanings of the labels in the diagram are as follows:

[0025] 1. Vacuum waste liquid tank; 2. Filter bag; 3. Piping; 4. Pump body; 5. Obstruction; 6. Photoelectric component; 61. Light-emitting element; 62. Photosensitive element. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", and "outer" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0028] See Figures 1-3 This embodiment discloses a liquid level detection device, which is used in an exosome purification waste liquid collection device and is used in conjunction with a vacuum waste liquid tank 1 for collecting exosome purification waste liquid. The device detects the liquid level in the vacuum waste liquid tank 1, assists in accurate drainage, and prevents air bubbles from being discharged.

[0029] The exosome purification waste liquid collection equipment includes a vacuum waste liquid tank 1 and a filter bag 2. In practical applications, the outlet end of the vacuum waste liquid tank 1 is connected to the inlet end of the filter bag 2 through a pipeline 3. The pipeline 3 is connected to a pump body 4, such as a peristaltic pump.

[0030] Specifically, the liquid level detection device includes a shield 5 installed in the vacuum waste liquid tank 1 and two sets of photoelectric components 6 installed outside the vacuum waste liquid tank 1. The shield 5 and the photoelectric components 6 work together to achieve liquid level detection at different heights.

[0031] In this embodiment, the specific gravity of the shield 5 is less than that of water. When the vacuum waste liquid tank 1 contains liquid, the shield 5 can float on the surface of the liquid in the vacuum waste liquid tank 1 and can rise and fall synchronously with the surface of the liquid in the vacuum waste liquid tank 1.

[0032] To avoid any deviation in the occlusion caused by the obstruction object 5, in this embodiment, the obstruction object 5 is an opaque solid object to ensure its effectiveness in occlusion.

[0033] like Figure 2 As shown, the two sets of photoelectric components 6 are the first photoelectric component 6 corresponding to the upper position of the vacuum waste liquid tank 1 and the second photoelectric component 6 corresponding to the lower position of the vacuum waste liquid tank 1.

[0034] The first photoelectric component 6 includes a light-emitting element 61 disposed on one side of the vacuum waste liquid tank 1 and a photosensitive element 62 disposed on the other side of the vacuum waste liquid tank 1. The light-emitting element 61 and the photosensitive element 62 are at the same height and are disposed opposite to each other. Liquid level detection is achieved by blocking the light path of the light-emitting element 61 through the obstruction 5 that undulates with the liquid surface.

[0035] The second photoelectric component 6 has the same structure as the first photoelectric component 6, and the two are used to detect liquid levels at different heights.

[0036] Specifically, in this embodiment, the liquid level information detected by the first photoelectric component 6, positioned slightly above the vacuum waste liquid tank 1, serves as the signal for the vacuum waste liquid tank 1 to begin discharging, while the liquid level information detected by the second photoelectric component 6, positioned slightly below the vacuum waste liquid tank 1, serves as the signal for the vacuum waste liquid tank 1 to stop discharging. The height of the first photoelectric component 6 is set within the range of 80%-85% of the total height of the vacuum waste liquid tank 1 to avoid areas prone to foam accumulation. The height of the second photoelectric component 6 is set within the range of 15%-20% of the total height of the vacuum waste liquid tank 1. Based on the foam characteristics of the exosome purification waste liquid, this height range allows a certain liquid layer to be retained at the bottom of the tank, forming a physical barrier to ensure that the remaining liquid level after discharging does not trigger foam inhalation.

[0037] In a preferred embodiment, to prevent the shielding object 5 from tilting, the shielding object 5 is generally constructed as a rectangular structure with uniform mass to ensure that its height above the liquid surface is uniform, while preventing irregular shapes from causing detection errors in the photoelectric component 6. Preferably, the shielding object 5 has an arc-shaped bottom to reduce tension and promote its buoyancy. Furthermore, to prevent the shielding object 5 from becoming unstable due to liquid turbulence, in this embodiment, the bottom of the shielding object 5 is also provided with an openable counterweight cavity (not shown in the figure). An adjustable counterweight material is embedded in the counterweight cavity. The buoyancy and center of gravity of the shielding object 5 are adjusted by the adjustable counterweight material to ensure its vertical floating stability. For example, the adjustable counterweight material can be stainless steel pellets or lead pellets, etc. It is understood that the counterweight cavity needs to be used with a sealing structure such as a sealing ring or sealing gasket to prevent liquid seepage.

[0038] In a preferred embodiment, the width of the shield 5 needs to be greater than half the width or diameter of the vacuum waste tank 1 to ensure its effectiveness in shielding.

[0039] In a preferred embodiment, the shield 5 is made of a hydrophobic material or coated with a hydrophobic coating to reduce the adhesion of foam or other debris to the surface of the shield 5, thereby reducing interference with the optical path. For example, the hydrophobic material can be polytetrafluoroethylene, polyethylene, etc.

[0040] For ease of understanding, the waste liquid collection method of the exosome purification waste liquid collection device in this embodiment is described as follows:

[0041] Method 1

[0042] 1. Vacuum waste liquid tank 1 collects waste liquid containing foam;

[0043] 2. The rise in the liquid level inside the vacuum waste liquid tank 1 causes the obstruction 5 to move upward;

[0044] 3. When the obstruction 5 blocks the optical path of the first photoelectric component, the peristaltic pump starts and begins to drain the liquid;

[0045] 4. When the light path to the second photoelectric component is blocked, turn off the peristaltic pump to stop the drainage and avoid discharging air bubbles or foam into the filter bag 2, which may cause the bag to swell.

[0046] 5. Repeat steps 1-4 above until purification is complete;

[0047] 6. After purification, the peristaltic pump actively drains the liquid until the light path of the second photoelectric component is blocked, and then drains for a fixed period of time. The specific time is calculated based on the volume of the vacuum waste liquid tank 1 and the pump flow rate, until the vacuum waste liquid tank 1 is emptied.

[0048] Method 2

[0049] 1. Vacuum waste liquid tank 1 collects waste liquid containing foam;

[0050] 2. The rise in the liquid level inside the vacuum waste liquid tank 1 causes the obstruction 5 to move upward;

[0051] 3. When the obstruction 5 blocks the optical path of the first photoelectric component, the peristaltic pump starts and begins to drain the liquid;

[0052] 4. When the light path to the second photoelectric component is blocked, turn off the peristaltic pump to stop the drainage and avoid discharging air bubbles or foam into the filter bag 2, which may cause the bag to swell.

[0053] 5. Continue collecting waste liquid. When the optical path of the second photoelectric component is not blocked, the peristaltic pump starts to discharge liquid until the optical path of the second photoelectric component is blocked.

[0054] 6. Repeat step 5 until purification is complete;

[0055] 7. After purification, the peristaltic pump actively drains the liquid until the light path of the second photoelectric component is blocked, and then drains for a fixed period of time. The specific time is calculated based on the volume of the vacuum waste liquid tank 1 and the pump flow rate, until the vacuum waste liquid tank 1 is emptied.

[0056] It is understood that the above-mentioned actions are all controlled by the control module. The control module receives the liquid level detection data from the photoelectric component 6 and controls the opening and closing of the pump body 4 accordingly. This control mode is a mature existing technology and will not be described in detail in this embodiment.

[0057] The liquid level detection device and exosome purification waste liquid collection equipment provided in this embodiment can, on the one hand, avoid the influence of complex liquid environments, especially the problem of interference from intermediate bubble states. During detection, there are only two states: whether the light path is blocked or not. This is reflected in the signal strength threshold, which can be set to "with liquid" (0-500) and "without liquid" (500-22000), thereby making the liquid level detection more accurate and reducing false alarms. On the other hand, by setting two sets of photoelectric components 6 at the top and bottom and specifically setting their height, the opening and closing time of the peristaltic pump can be precisely controlled, avoiding the problem of a large number of bubbles entering the external filter bag 2 during the collection of purification waste liquid, causing bag swelling and other problems. In addition, the waste liquid tank does not integrate sensors, and the non-contact design can effectively extend its service life, and the internal obstruction 5 can be replaced at low cost.

[0058] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A liquid level detection device, used in conjunction with a vacuum waste liquid tank (1) for collecting waste liquid from exosome purification, characterized in that, include: The shield (5) is installed inside the vacuum waste liquid tank (1). When the vacuum waste liquid tank (1) contains liquid, the shield (5) floats on the liquid surface of the vacuum waste liquid tank (1) and rises and falls synchronously with the liquid surface of the vacuum waste liquid tank (1). The photoelectric component (6) is located outside the vacuum waste liquid tank (1). The photoelectric component (6) is configured in two sets, namely a first photoelectric component corresponding to the upper position of the vacuum waste liquid tank (1) and a second photoelectric component corresponding to the lower position of the vacuum waste liquid tank (1). The photoelectric component (6) and the shield (5) are used together for liquid level detection.

2. The liquid level detection device according to claim 1, characterized in that, The obstruction (5) is an opaque solid object.

3. The liquid level detection device according to claim 1, characterized in that, The photoelectric component (6) includes a light-emitting element (61) disposed on one side of the vacuum waste liquid tank (1) and a photosensitive element (62) disposed on the other side of the vacuum waste liquid tank (1). The light-emitting element (61) and the photosensitive element (62) are of the same height and are disposed opposite to each other.

4. The liquid level detection device according to claim 1, characterized in that, The height of the first optoelectronic component is set within the range of 80%-85% of the total height of the vacuum waste liquid tank (1).

5. The liquid level detection device according to claim 1, characterized in that, The height of the second photoelectric component is set within the range of 15%-20% of the total height of the vacuum waste liquid tank (1).

6. The liquid level detection device according to claim 1, characterized in that, The shield (5) is constructed as a rectangular structure with uniform mass.

7. The liquid level detection device according to claim 6, characterized in that, The width of the obstruction (5) is greater than 1 / 2 of the width or diameter of the vacuum waste liquid tank (1).

8. The liquid level detection device according to claim 6, characterized in that, The bottom of the shield (5) is also provided with an openable counterweight cavity, and an adjustable counterweight material is embedded in the counterweight cavity.

9. The liquid level detection device according to claim 1, characterized in that, The shield (5) is made of a hydrophobic material or the surface of the shield (5) is coated with a hydrophobic coating.

10. A waste liquid collection device for exosome purification, characterized in that, It includes a vacuum waste liquid tank (1) and a filter bag (2). The outlet end of the vacuum waste liquid tank (1) is connected to the inlet end of the filter bag (2) through a pipeline (3). The pipeline (3) is connected to a pump body (4). The vacuum waste liquid tank (1) is connected to the liquid level detection device according to any one of claims 1-9.

Images