Traditional Chinese medicine tea bag device capable of adjusting drug effect release rate

Abstract

The utility model relates to the field of traditional Chinese medicine teabag, in particular to a traditional Chinese medicine teabag device capable of adjusting drug effect release rate, which comprises a teabag body, the teabag body comprises a laser drilling nylon film, a poly (lactic-co-glycolic acid) (PLGA) film and a sintered polyethylene film, the laser drilling nylon film, the PLGA film and the sintered polyethylene film are subjected to edge fusion through a hot-pressing compounding process to form an upper-layer quick release cavity positioned between the laser drilling nylon film and the PLGA film and a lower-layer slow release cavity positioned between the laser drilling nylon film and the PLGA film and the sintered polyethylene film. Compared with a common traditional Chinese medicine tea bag at present, the problem of medicine residue leakage caused by high-temperature breakage of the tea bag body can be effectively solved. Meanwhile, through staged release of the medicine components, the medicine effect utilization rate can be well increased.

Description

Technical Field

[0001] This utility model relates to the field of Chinese herbal tea bags, specifically to a Chinese herbal tea bag device with adjustable drug release rate. Background Technology

[0002] Herbal tea bags are a new type of health drink made from Chinese medicinal herbs, processed into granules or powder using modern technology, and then packaged into individual tea bags for convenient brewing. They integrate traditional Chinese medicine theory with modern convenience and have rapidly gained popularity in the health consumer market in recent years. Currently, herbal tea bags are used in...

[0003] Currently, common Chinese herbal tea bags are usually made of single-layer non-woven fabric bags or ordinary filter paper. Single-layer non-woven fabric bags cannot distinguish between fast-acting and slow-release components, causing volatile active ingredients (such as menthol) to be rapidly lost at high temperatures. Ordinary filter paper is prone to breakage in hot water above 80°C, with a residue leakage rate of up to 15%.

[0004] Therefore, choosing the appropriate material and structure for Chinese herbal tea bags is a crucial issue that must be addressed to improve the effectiveness of Chinese herbal tea bags. Summary of the Invention

[0005] To solve the above-mentioned technical problems, the present invention provides a solution through the following technical method:

[0006] A herbal tea bag device with adjustable drug release rate includes a tea bag body, which comprises a laser-perforated nylon film, a PLGA film, and a sintered polyethylene film. The laser-perforated nylon film, PLGA film, and sintered polyethylene film are edge-fused together by a hot-pressing composite process to form an upper rapid-release cavity located between the laser-perforated nylon film and the PLGA film, and a lower slow-release cavity located between the laser-perforated nylon film and the sintered polyethylene film.

[0007] As a preferred embodiment of the present invention, the PLGA membrane includes three PLGA valves arranged radially. When closed, the tips of the PLGA valves contact to form a 0.5 mm aperture. At 60°C, the material undergoes a glass transition, and the PLGA valve expands to a 120° angle, increasing the aperture to 1.5 mm.

[0008] As a preferred embodiment of this utility model, the PLGA valve has an LA:GA ratio of 75:25.

[0009] As a preferred embodiment of this utility model, a connecting seat is adhered to the upper surface of the laser-perforated nylon film, and a hanging rope is adhered to the connecting seat.

[0010] As a preferred embodiment of this utility model, a mounting base is provided at the bottom end face of the sintered polyethylene film, and a counterweight ball is provided at the mounting base.

[0011] The beneficial effects that can be achieved by adopting the above technical solution are as follows:

[0012] 1. Compared to commonly used herbal tea bags, this invention not only effectively prevents the leakage of medicinal residue caused by the high-temperature rupture of the tea bag, but also significantly improves the utilization rate of the medicinal components through the phased release of the medicinal ingredients. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the herbal tea bag device with adjustable drug release rate in Example 1.

[0014] Figure 2 for Figure 1 A cross-sectional view of a Chinese herbal tea bag device with adjustable drug release rate.

[0015] The attached figures are labeled as follows: 100, tea bag body; 110, connecting seat; 120, connecting seat; 210, laser-perforated nylon film; 220, laser-perforated nylon film; 230, sintered polyethylene film; 240, upper quick-release chamber; 250, lower slow-release chamber; 260, lower slow-release chamber; 270, counterweight ball. Detailed Implementation

[0016] To further understand the content of this utility model, a detailed description of this utility model will be provided in conjunction with the accompanying drawings and embodiments. It should be understood that the embodiments are merely illustrative of this utility model and are not intended to limit it.

[0017] Example 1

[0018] like Figure 1-2 As shown, this embodiment provides a herbal tea bag device with adjustable drug release rate, comprising a tea bag body 110. The tea bag body 110 includes a laser-perforated nylon film 210 (pore diameter 80±5μm, pore spacing 200±10μm), a PLGA film 220 (thickness 50±2μm), and a sintered polyethylene film 230 (pore diameter 20±1μm, porosity 65%). The laser-perforated nylon film 210, PLGA film 220, and sintered polyethylene film 230 are edge-fused by a hot-pressing composite process to form an upper rapid-release cavity 240 between the laser-perforated nylon film 210 and the PLGA film 220, and a lower slow-release cavity 250 between the laser-perforated nylon film 210 and the sintered polyethylene film 230. A connecting seat 110 is bonded to the upper end face of the laser-perforated nylon film 210, and a hanging rope 120 is bonded to the connecting seat 110. A mounting base 260 is provided at the bottom end of the sintered polyethylene film 230, and a counterweight ball 270 is provided at the mounting base 260.

[0019] model Aperture (μm) Hole spacing (μm) Thickness (μm) Open area ratio (%) Applicable Standards Whatman Nuclepore™ 800309 80±2 200±5 8±0.5 10.8 JISK6404-7

[0020] Model (Supplier) LA:GA ratio Thickness (μm) Initial pore size (μm) Degradation cycle (days) Swelling rate (%) Elongation at break (%) Evonik Resomer® RG 756S 75:25 50±1.5 5-15 (Dynamic) 30-45 12±2 280±20

[0021] In this embodiment, the sintered polyethylene membrane 230 preferably uses Porex® X-4939 filter membrane. This model can achieve a cumulative release rate of 92.3±2.1% (compared to 87.5±3.4% for the control) in the sustained-release experiment of kudzu flavonoids, and the batch-to-batch difference RSD is <1.5%.

[0022] Suppliers and Models Nominal pore size (μm) Measured pore size distribution (μm) Porosity (%) Flux (L / m²·h·bar) Certification Standards Porex® X-4939 20±0.8 18.5-21.2 (D90) 65±2 850±50 USP Class VI

[0023] Combination Figure 2 As shown, the PLGA membrane 220 includes three PLGA valves, with LA:GA = 75:25 in the PLGA valves; the three PLGA valves are arranged radially, and when closed, the tips of the PLGA valves contact to form a 0.5mm aperture. At 60°C, the material undergoes a glass transition, and the PLGA valve expands to a 120° angle, increasing the aperture to 1.5mm.

[0024] Before use, the laser-perforated nylon membrane 210, PLGA membrane 220, and sintered polyethylene membrane 230 are pre-sealed. Then, different traditional Chinese medicine materials are placed in the upper immediate-release chamber 240 and the lower sustained-release chamber 250, respectively. During use, the tea bag body 110 is placed in the cup, and then hot water at 100℃ is added. Due to the difference in pore size between the laser-perforated nylon membrane 210 in the upper immediate-release chamber 240 and the sintered polyethylene membrane 230 in the lower sustained-release chamber 250, the medicinal components are released in stages. The PLGA membrane 220 automatically expands its release pores at 60℃ to accelerate the dissolution of components in the upper immediate-release chamber 240 and the lower sustained-release chamber 250, thereby improving the fusion effect of the traditional Chinese medicine materials in the upper immediate-release chamber 240 and the lower sustained-release chamber 250.

[0025] Because laser-perforated nylon film 210, PLGA film 220, and sintered polyethylene film 230 all possess excellent heat resistance, the herbal tea bag device with adjustable drug release rate in this embodiment can more effectively prevent the leakage of medicinal residue caused by high-temperature rupture of the tea bag body 110 compared to commonly used herbal tea bags. Simultaneously, the phased release of medicinal components can significantly improve the utilization rate of the medicine.

[0026] The tea bag body 110 is also equipped with a bromocresol purple pH-responsive strip, which is installed around the tea bag body 110 at a distance of 24015mm from the upper quick-release chamber. The bromocresol purple pH-responsive strip is covered with a medical-grade PET film (0.2mm thick) with a size of 8mm×60mm (covering the detection strip + 2mm edge), a light transmittance of ≥90%, and a haze of ≤5%. Double-sided medical pressure-sensitive tape (3mm wide) is also provided for fixing the bromocresol purple pH-responsive strip.

[0027] Example 2

[0028] In this embodiment, the working principle of the device is illustrated by taking catnip spikes and kudzu root as examples.

[0029] loading process

[0030] The upper immediate-release chamber is filled with 5g of catnip spikes (40 mesh), and the lower slow-release chamber is filled with 3g of kudzu root (80 mesh).

[0031] Soaking stage

[0032] Time (min) Temperature (°C) PH Response stripe color Release rate of the upper immediate-release chamber (%) Release rate (%) of the lower sustained-release chamber 3 80 5.2 light yellow 89 8 15 60 6.0 Yellow-purple gradient 93 55 30 ＜60 6.8 Deep purple 95 82

[0033] According to the table above, the optimal drinking temperature is 60℃ (when the bromocresol purple pH response band turns dark purple), at which point the pueraria flavonoids and schizonepeta spike volatile oil reach the golden ratio (1:2.3).

[0034] In summary, the tea bag body 110 formed by laser-perforated nylon film 210, PLGA film 220, and sintered polyethylene film 230 can control the phased release of kudzu flavonoids and schizonepeta spike volatile oil, and achieve a golden ratio at 60℃, thereby better improving the efficacy of the medicine.

[0035] In summary, the above description is only a preferred embodiment of the present utility model. All equivalent changes and modifications made within the scope of the patent application of the present utility model shall fall within the scope of the patent of the present utility model.

Claims

1. A herbal tea bag device with adjustable drug release rate, characterized in that: The tea bag body (110) includes a laser-perforated nylon film (210), a PLGA film (220), and a sintered polyethylene film (230). The laser-perforated nylon film (210), PLGA film (220), and sintered polyethylene film (230) are edge-fused together by a hot-pressing composite process to form an upper fast-release cavity (240) between the laser-perforated nylon film (210) and the PLGA film (220) and a lower slow-release cavity (250) between the laser-perforated nylon film (210) and the PLGA film (220).

2. The herbal tea bag device with adjustable drug release rate according to claim 1, characterized in that: The PLGA membrane (220) includes three PLGA valves arranged radially. When closed, the tips of the PLGA valves contact to form a 0.5 mm aperture. At 60°C, the material undergoes a glass transition, and the PLGA valve expands to a 120° angle, increasing the aperture to 1.5 mm.

3. The herbal tea bag device with adjustable drug release rate according to claim 2, characterized in that: In PLGA valves, LA:GA = 75:

25.

4. The herbal tea bag device with adjustable drug release rate according to claim 1, characterized in that: A connector (110) is attached to the upper end of the laser-perforated nylon film (210), and a hanging rope (120) is attached to the connector (110).

5. The herbal tea bag device with adjustable drug release rate according to claim 1, characterized in that: A mounting base (260) is provided at the bottom end of the sintered polyethylene film (230), and a counterweight ball (270) is provided at the mounting base (260).

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