Test animal brain tissue extractor

Abstract

The utility model provides a brain tissue extractor for an experimental animal. The brain tissue extractor comprises a cutting device and a driving device, the cutting device comprises a base and two cutting mechanisms. Each cutting mechanism comprises a rotating shaft, a cutting blade, an adjusting assembly and a driving part. The rotating shaft is rotatably installed on the base, the two cutting blades are coaxially installed on the rotating shaft through an adjusting assembly, and the adjusting assembly can adjust the positions of the cutting blades in the length direction of the rotating shaft; the driving piece can drive the rotating shaft to rotate; wherein the two rotating shafts are arranged in a mutually perpendicular and staggered mode, and a rectangular shape is defined by the four cutting blades; the driving device can drive the cutting device to move in the cutting direction of the cutting blade. The skull of the test animal is cut by the four cutting blades which form the rectangle, so that a rectangular opening can be cut on the skull of the test animal. Therefore, a hand-held angle grinder is replaced for opening, so that the risk of operators can be effectively reduced, and more time and labor are saved.

Description

Technical Field

[0001] This utility model relates to the field of experimental animal brain tissue extraction technology, specifically to an experimental animal brain tissue extraction device. Background Technology

[0002] The use of animal models in neuropsychiatric disease research is essential. This is because neuropsychiatric diseases often involve complex neural circuits and molecular mechanisms, making direct study in humans difficult. Animal models allow for better investigation of the pathogenesis and pathophysiology of neuropsychiatric diseases, as well as the evaluation of the effectiveness and safety of treatments. These animal models provide a systematic, controlled, and reproducible approach to help scientists study the occurrence and development of these diseases. Using animal models in neuropsychiatric disease research also contributes to the development of new drugs and treatments. Brain tissue is a crucial material in neuropsychiatric disease research, providing vital information for studying neurons, neural circuits, and neurotransmitters, yielding a wealth of useful data.

[0003] Currently, the conventional method for obtaining brain tissue from laboratory animals is to use an angle grinder to cut a rectangle in the skull, remove the skull, and then extract the brain tissue. This method poses risks to the operator and is time-consuming and labor-intensive. Utility Model Content

[0004] In view of the above-mentioned problems in the existing technology, the technical problem to be solved by this utility model is: the conventional method of obtaining brain tissue from experimental animals is to use an angle grinder to cut a rectangle on the skull, remove the skull, and then take out the brain tissue. This method poses risks to the operator and is also time-consuming and labor-intensive.

[0005] To solve the above-mentioned technical problems, the present invention adopts the following technical solution: a brain tissue extraction device for experimental animals, comprising:

[0006] A cutting device includes a base and two cutting mechanisms. Each cutting mechanism includes a rotating shaft, cutting blades, an adjusting assembly, and a driving component. The rotating shaft is rotatably mounted on the base. The two cutting blades are coaxially mounted on the rotating shaft via the adjusting assembly, and the adjusting assembly can adjust the position of the cutting blades along the length of the rotating shaft. The driving component can drive the rotating shaft to rotate. The two rotating shafts are arranged perpendicularly to each other and staggered, and the four cutting blades form a rectangular shape.

[0007] The driving device can drive the cutting device to move in the cutting direction of the cutting blade.

[0008] Preferably, the adjusting component includes: a sliding sleeve and a limiting member; the sliding sleeve is slidably sleeved on the rotating shaft, the cutting blade is mounted on the sliding sleeve, and the limiting member can restrict the sliding of the sliding sleeve.

[0009] Preferably, the limiting component includes: an insertion rod and a rotating rod; a plurality of spaced limiting holes are provided along the length direction of the rotating shaft, the limiting holes being perpendicular to the axis of the rotating shaft; an insertion hole perpendicular to the axis of the sliding sleeve is provided on the sliding sleeve; the insertion rod and the rotating rod are slidably inserted into the limiting holes and the insertion holes; one end of the insertion rod is provided with a polygonal limiting part, and one end of the insertion hole is provided with a polygonal groove that mates with the polygonal limiting part; the other end of the insertion rod is provided with a threaded hole coaxial with the insertion part; one end of the rotating rod is provided with a threaded insertion part, the threaded insertion part being threadedly engaged with the threaded hole; the other end of the rotating rod is provided with a torsion part.

[0010] Preferably, the driving device includes a base, a column, a lead screw, a nut seat, an extension arm, and a power component; the column is vertically mounted on the base; the lead screw is parallel to the column and rotatably mounted on the column; the nut seat is slidably mounted on the column along the length of the lead screw and is threadedly connected to the lead screw; one end of the extension arm is fixedly mounted on the nut seat and is perpendicular to the column; the other end of the extension arm is fixedly connected to the base; and the power component can drive the lead screw to rotate.

[0011] Preferably, the length of the extension arm is adjustable.

[0012] Compared with the prior art, the present invention has at least the following advantages:

[0013] 1. In this invention, after fixing the head of the experimental animal, the scalp is removed, and the position of the cutting blades along the length of the rotating shaft is adjusted according to the size of the animal's skull. This adjusts the size of the rectangle formed by the four cutting blades. After adjustment, the drive mechanism is activated, driving the rotating shaft to rotate, which in turn rotates the cutting blades via the adjustment assembly. Finally, the drive device is activated, moving the cutting device toward the animal's head, thereby moving the cutting blades toward the skull. The four cutting blades forming the rectangle cut into the skull, creating a rectangular opening that allows the brain tissue to be extracted. This method replaces the use of a handheld angle grinder, effectively reducing operator risk and saving time and effort.

[0014] 2. In this invention, the position of the cutting blade on the axis of rotation is adjusted by sliding the sliding sleeve, thereby adjusting the distance between two parallel cutting blades and thus adjusting the size of the rectangular incision on the skull of the experimental animal.

[0015] 3. In this utility model, a sliding sleeve is used to adjust the position of the cutting blade, so that the insertion hole on the sliding sleeve is coaxially set with the corresponding limiting hole on the rotating shaft. Then, the insertion rod is inserted into the insertion hole and the limiting hole in sequence, so that the polygonal limiting part at one end of the insertion rod is engaged in the polygonal groove, and the threaded hole at the other end of the insertion rod moves into the limiting hole. Then, the rotating rod is inserted into the insertion hole and the limiting hole in sequence through the other end, so that the threaded insertion part at one end of the rotating rod moves into the limiting hole, and the torsion part at the other end of the rotating rod is located outside the insertion hole and the limiting hole. Then, the polygonal limiting part is pressed, so that the polygonal limiting part is engaged in the polygonal groove, thereby restricting the rotation of the insertion rod. Then, the rotating rod is rotated by the torsion part, and the rotating rod drives the threaded insertion part to rotate, so that the threaded insertion part engages with the threaded hole. In this way, the insertion rod and the rotating rod can be connected, and the setting of the polygonal limiting part and the torsion part can prevent the insertion rod and the rotating rod from sliding out of the insertion hole and the limiting hole. Attached Figure Description

[0016] To more clearly illustrate the specific embodiments of this utility model, the accompanying drawings used in the specific embodiments will be briefly described below. In all the drawings, the elements or parts are not necessarily drawn to scale.

[0017] Figure 1 This is a perspective view of a brain tissue extraction device for experimental animals provided in an embodiment of this utility model.

[0018] Figure 2 This is a perspective view of the cutting device provided in an embodiment of the present invention.

[0019] Figure 3 This is a partial top view of the cutting device provided in an embodiment of the present invention.

[0020] Figure 4 This is a cross-sectional view of the adjustment component provided in an embodiment of the present invention.

[0021] Reference numerals: 1-Cutting device, 11-Base, 12-Rotating shaft, 13-Cutting blade, 14-Limiting hole, 2-Drive device, 21-Base, 22-Column, 23-Screw rod, 24-Nut seat, 25-Extension arm, 26-Power component, 3-Adjusting assembly, 31-Sliding sleeve, 32-Insertion rod, 33-Rotating rod, 34-Insertion hole, 35-Polygonal limiting part, 36-Threaded hole, 37-Threaded insertion part, 38-Torsion part, 39-Polygonal groove. Detailed Implementation

[0022] The embodiments of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the present invention and should not be construed as limiting the scope of protection of the present invention.

[0023] In this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0024] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0025] See Figures 1-4 The present invention provides an embodiment of a brain tissue extractor for experimental animals, comprising: a cutting device 1 and a driving device 2; the cutting device 1 includes a base 11 and two cutting mechanisms, each cutting mechanism including: a rotating shaft 12, cutting blades 13, an adjusting component 3, and a driving component; the rotating shaft 12 is rotatably mounted on the base 11, and the two cutting blades 13 are coaxially mounted on the rotating shaft 12 via the adjusting component 3, and the adjusting component 3 can adjust the position of the cutting blades 13 in the length direction of the rotating shaft 12; the driving component can drive the rotating shaft 12 to rotate; specifically, the driving component is a motor; wherein, the two rotating shafts 12 are arranged perpendicularly to each other, and the four cutting blades 13 form a rectangular shape; the driving device 2 can drive the cutting device 1 to move toward the cutting direction of the cutting blades 13.

[0026] In practice, after fixing the head of the experimental animal, the scalp is removed, and the position of the cutting blades 13 along the length of the rotating shaft 12 is adjusted according to the size of the animal's skull. This adjusts the size of the rectangle formed by the four cutting blades 13. After adjustment, the drive mechanism is activated, driving the rotating shaft 12 to rotate, which in turn rotates the cutting blades 13 via the adjustment assembly 3. Finally, the drive device 2 is activated, moving the cutting device 1 toward the animal's head, thereby moving the cutting blades 13 toward the skull. The four cutting blades 13 cutting the skull create a rectangular opening, allowing the brain tissue to be extracted. This method replaces the use of a handheld angle grinder, effectively reducing operator risk and saving time and effort.

[0027] See Figures 1-4 In other embodiments, the adjustment component 3 includes a sliding sleeve 31 and a limiting member; the sliding sleeve 31 is slidably sleeved on the rotating shaft 12, the cutting blade 13 is mounted on the sliding sleeve 31, and the limiting member restricts the sliding of the sliding sleeve 31. By sliding the sliding sleeve 31, the position of the cutting blade 13 along the length of the rotating shaft 12 can be adjusted, thereby adjusting the distance between two parallel cutting blades 13, and thus adjusting the size of the rectangular incision on the skull of the test animal; after adjustment, the limiting member restricts the sliding of the sliding sleeve 31, and thus preparation for cutting can begin.

[0028] See Figures 1-4 In other embodiments, the limiting components include: a plug rod 32 and a rotating rod 33; a plurality of spaced limiting holes 14 are provided along the length of the rotating shaft 12, the limiting holes 14 being perpendicular to the axis of the rotating shaft 12; a sliding sleeve 31 is provided with a insertion hole 34 perpendicular to the axis of the sliding sleeve 31; both the plug rod 32 and the rotating rod 33 are slidably inserted into the limiting hole 14 and the insertion hole 34; one end of the plug rod 32 is provided with a polygonal limiting part 35, and one end of the insertion hole 34 is provided with a polygonal groove 39 that mates with the polygonal limiting part 35; the other end of the plug rod 32 is provided with a threaded hole 36 coaxial with the insertion; one end of the rotating rod 33 is provided with a threaded insertion part 37, the threaded insertion part 37 being threadedly engaged with the threaded hole 36; the other end of the rotating rod 33 is provided with a twisting part 38.

[0029] In practice, the sliding sleeve 31 is slidable to adjust the position of the cutting blade 13, so that the insertion hole 34 on the sliding sleeve 31 is coaxially aligned with the corresponding limiting hole 14 on the rotating shaft 12. Then, the insertion rod 32 is sequentially inserted into the insertion hole 34 and the limiting hole 14, so that the polygonal limiting part 35 at one end of the insertion rod 32 engages in the polygonal groove 39, and the threaded hole 36 at the other end of the insertion rod 32 moves into the limiting hole 14. Then, the rotating rod 33 is sequentially inserted into the insertion hole 34 and the limiting hole 14 through the other end, so that the threaded insertion part 37 at one end of the rotating rod 33 moves into the limiting hole 14. The torsion part 38 at the other end of the moving rod 33 is located outside the insertion hole 34 and the limiting hole 14. The polygonal limiting part 35 is then pressed, so that the polygonal limiting part 35 is engaged in the polygonal groove 39, thereby restricting the rotation of the insertion rod 32. Then, the rotating rod 33 is rotated by the torsion part 38, and the rotating rod 33 drives the threaded insertion part 37 to rotate, so that the threaded insertion part 37 engages with the threaded hole 36. In this way, the insertion rod 32 and the rotating rod 33 can be connected, and the setting of the polygonal limiting part 35 and the torsion part 38 restricts the insertion rod 32 and the rotating rod 33 from sliding out of the insertion hole 34 and the limiting hole 14.

[0030] See Figures 1-4 In another embodiment, the driving device 2 includes: a base 21, a column 22, a lead screw 23, a nut seat 24, an extension arm 25, and a power component 26; the column 22 is vertically mounted on the base 21; the lead screw 23 is arranged parallel to the column 22 and is rotatably mounted on the column 22; the nut seat 24 is slidably mounted on the column 22 along the length direction of the lead screw 23, and the nut seat 24 is threadedly connected to the lead screw 23; one end of the extension arm 25 is fixedly mounted on the nut seat 24, and the extension arm 25 is perpendicular to the column 22; the other end of the extension arm 25 is fixedly connected to the base 21; furthermore, the length of the extension arm 25 is adjustable; by adjusting the length of the extension arm 25, the position of the cutting blade 13 can be adjusted, thereby facilitating the alignment of the cutting blade 13 with the skull of the experimental animal; the power component 26 can drive the lead screw 23 to rotate.

[0031] In practice, the power component 26 is a motor; the base 21 is installed on the test bench, and the power component 26 is controlled to move. The power component 26 drives the lead screw 23 to rotate, the lead screw 23 drives the nut seat 24 to slide, and the nut seat 24 drives the base 11 to move toward the head of the test animal through the extension arm 25. In this way, the cutting blade 13 can be moved toward the skull of the test animal, and the skull of the test animal is cut by the four cutting blades 13 that form a rectangle.

[0032] The above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model, and they should all be covered within the scope of the claims and specification of this utility model.

Claims

1. A brain tissue extraction device for experimental animals, characterized in that, include: A cutting device includes a base and two cutting mechanisms. Each cutting mechanism includes a rotating shaft, cutting blades, an adjusting assembly, and a driving component. The rotating shaft is rotatably mounted on the base. The two cutting blades are coaxially mounted on the rotating shaft via the adjusting assembly, and the adjusting assembly can adjust the position of the cutting blades along the length of the rotating shaft. The driving component can drive the rotating shaft to rotate. The two rotating shafts are arranged perpendicularly to each other and staggered, and the four cutting blades form a rectangular shape. The driving device can drive the cutting device to move in the cutting direction of the cutting blade.

2. The experimental animal brain tissue extraction device according to claim 1, characterized in that, The adjustment assembly includes a sliding sleeve and a limiting member; the sliding sleeve is slidably sleeved on the rotating shaft, the cutting blade is mounted on the sliding sleeve, and the limiting member can restrict the sliding of the sliding sleeve.

3. The experimental animal brain tissue extraction device according to claim 2, characterized in that, The limiting component includes: an insertion rod and a rotating rod; multiple spaced limiting holes are provided along the length of the rotating shaft, and the limiting holes are perpendicular to the axis of the rotating shaft; an insertion hole perpendicular to the axis of the sliding sleeve is provided on the sliding sleeve; the insertion rod and the rotating rod are slidably inserted into the limiting holes and the insertion holes; one end of the insertion rod is provided with a polygonal limiting part, and one end of the insertion hole is provided with a polygonal groove that mates with the polygonal limiting part; the other end of the insertion rod is provided with a threaded hole coaxial with the insertion part; one end of the rotating rod is provided with a threaded insertion part that is threadedly engaged with the threaded hole; the other end of the rotating rod is provided with a torsion part.

4. The experimental animal brain tissue extraction device according to claim 1, characterized in that, The driving device includes a base, a column, a lead screw, a nut seat, an extension arm, and a power component. The column is vertically mounted on the base. The lead screw is parallel to the column and rotatably mounted on the column. The nut seat is slidably mounted on the column along the length of the lead screw and is threadedly connected to the lead screw. One end of the extension arm is fixedly mounted on the nut seat and is perpendicular to the column. The other end of the extension arm is fixedly connected to the base. The power component can drive the lead screw to rotate.

5. The experimental animal brain tissue extraction device according to claim 4, characterized in that, The length of the extension arm is adjustable.

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