A heart stem cell injection solution packaging bag

Abstract

This utility model relates to a packaging bag for stem cell injection solution. The packaging bag includes a bag body and an infusion interface. The bag body includes a light-proof area and a transparent window area. The inner layer of the light-proof area is polytetrafluoroethylene (PTFE), and the outer layer is a dark-colored coating or dark-colored high-density polyethylene (HDPE). A sealing strip is provided between the transparent window area and the light-proof area. Compared with existing technologies, this packaging bag is specifically designed for the biochemical characteristics of cardiac stem cells and their injection solution. Using HDPE as the main material, it has good biocompatibility, non-stick properties, and thermal insulation, ensuring both the safety and stability of stem cell storage. The sealing strip between the transparent window area and the light-proof area prevents the injection solution from being exposed to the transparent area and deteriorating before use. A Luer-Lock interface with a double-sealing structure (sealing ring or threaded structure) ensures that the stem cell injection solution is leak-free and uncontaminated during storage and transportation.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical packaging materials, specifically to a packaging bag for stem cell injection solution. Background Technology

[0002] Mesenchymal stem cells (MSCs), as pluripotent stem cells, are widely used in the treatment of various refractory diseases due to their excellent self-renewal capacity, significant immunomodulatory effects, and multi-lineage differentiation potential. However, the stability and safety of stem cells in clinical applications remain key factors restricting their development. The storage conditions for mesenchymal stem cells are quite demanding. The composition of stem cell injection solutions is complex and unique, requiring storage under conditions of light protection, low temperature refrigeration, shock protection, and airtight sealing. Furthermore, materials in direct contact with the stem cell injection solution must meet appropriate biocompatibility and non-adhesive properties. Current ordinary infusion packaging bags are clearly unsuitable for packaging and clinical use of stem cell injection solutions. Utility Model Content

[0003] To overcome the above technical defects, this utility model provides a special packaging bag for cardiac stem cell injection.

[0004] The packaging bag includes a bag body and an infusion port located at the bottom of the bag body. The bag body includes a light-proof area and a transparent window area. The inner layer of the light-proof area is a polytetrafluoroethylene (PTFE) biocompatible layer, and the outer layer is a dark coating or a dark high-density polyethylene (HDPE) light-proof layer. The transparent window area is located at the top of the infusion port and is made of transparent polytetrafluoroethylene or high-density polyethylene material.

[0005] To balance light-protected storage with easy observation of remaining liquid volume and changes in liquid appearance during quality checks or infusions, a sealing strip is provided between the transparent window area and the light-protected area. This sealing strip can be torn open during infusion or quality testing, allowing liquid to flow from the light-protected area into the transparent window area.

[0006] Alternatively, the sealing strip between the transparent window area and the light-shielding area can be removed, and a light-shielding cover can be installed on the surface of the transparent window area.

[0007] To concentrate the infusion fluid at the infusion port during infusion, the lower part of the bag body is designed in an inverted trapezoidal shape.

[0008] The infusion port at the bottom of the bag body adopts the Luer-Lock interface, which is equipped with a sealing ring or thread structure, and the interface material is stainless steel or medical plastic.

[0009] The bag body has a hook at the top, making it more convenient to use during infusion.

[0010] The bag body has a transparent interlayer with built-in moisture-absorbing materials such as silicone.

[0011] The packaging bag has a capacity of 100-300 ml and dimensions of 8-12 cm in height, 5-9 cm in length, and 1-3 cm in width. This capacity is suitable for single-dose infusion use.

[0012] Compared to existing technologies, the packaging bag for Benxinsheng stem cell injection is specifically designed for the biochemical characteristics of stem cells and their injection solutions. Using HDPE as the main material, it boasts excellent biocompatibility and non-stickiness, while also providing some thermal insulation to help maintain temperature stability. This design balances the safety and stability of stem cell storage. The light-proof zone and transparent window area design allow for both light-proof storage and easy observation of remaining fluid volume and appearance changes during quality checks or infusions. A sealing strip between the transparent window area and the light-proof zone prevents the injection solution from being exposed to the transparent window area and deteriorating before use. The infusion interface uses a Luer-Lock connector with a double-sealing structure featuring a sealing ring or threaded structure, effectively preventing leakage, reducing evaporation, maintaining stable cell concentration, and ensuring that the stem cell injection solution is leak-free and uncontaminated during storage and transportation. Attached Figure Description

[0013] Appendix Figure 1 This is a longitudinal sectional view of the structure of an embodiment of this utility model. Detailed Implementation

[0014] The present invention will be further described below with reference to specific embodiments.

[0015] As shown in the attached diagram, the stem cell injection packaging bag of this embodiment includes a bag body 1, an infusion interface 4 located at the bottom of the bag body 1, and a hook 7. The bag body 1 includes a light-proof area 2 and a transparent window area 3. A sealing strip 6 is provided between the light-proof area 2 and the transparent window area 3. The sealing strip 6 can be torn open during infusion or quality testing, allowing liquid to flow from the light-proof area 2 into the transparent window area 3. Figure 5 shows the inlet for drug delivery. This inlet can adopt a Luer-Lock interface, which has a double sealing structure with a medical-grade silicone / rubber gasket sealing ring or a threaded structure, facilitating drug delivery while providing excellent leak-proof functionality. This packaging bag has a compact structure with a capacity of 200ml, or dimensions of 11cm high, 7cm long, and 3cm wide. Its small size makes it easy to carry and store, while integrating the Luer-Lock infusion interface 4 to ensure the convenience and safety of clinical infusion. At the top of the bag body 1, below the hook 7, there is a PTFE transparent interlayer 8 measuring 2.5×2cm, with a non-woven fabric pouch measuring 1.7×1.5cm inside, containing silicone to regulate humidity.

Claims

1. A packaging bag for a cardiac stem cell injection solution, comprising a bag body and an infusion port located at the lower part of the bag body, characterized in that: The bag body includes a light-shielding area and a transparent window area. The inner layer of the light-shielding area is polytetrafluoroethylene, and the outer layer is a dark coating or dark high-density polyethylene. The transparent window area is located at the upper end of the infusion interface and is made of transparent polytetrafluoroethylene or high-density polyethylene.

2. The packaging bag as described in claim 1, characterized in that: A sealing strip is provided between the transparent window area and the light-blocking area.

3. The packaging bag as described in claim 1, characterized in that: The surface of the transparent window area is provided with a light-shielding cover.

4. The packaging bag as described in claim 1, 2, or 3, characterized in that: The lower part of the bag body is an inverted trapezoidal shape.

5. The packaging bag as described in claim 1, 2, or 3, characterized in that: The infusion port at the bottom of the bag body adopts a Luer-Lock interface. The infusion port is equipped with a sealing ring or a threaded structure. The infusion port material is stainless steel or medical plastic.

6. The packaging bag as described in claim 1, 2, or 3, characterized in that: The bag body has a hook at the top.

7. The packaging bag as described in claim 1, 2, or 3, characterized in that: The bag body has a hook at the top.

8. The packaging bag as described in claim 1, 2, or 3, characterized in that... The bag body has a transparent interlayer with built-in moisture-absorbing material.

9. The packaging bag as described in claim 8, characterized in that... The moisture-absorbing material is silica gel.

10. The packaging bag as described in claim 1, 2, or 3, characterized in that... The packaging bag has a capacity of 100-300 ml and dimensions of 8-12 cm in height, 5-9 cm in length, and 1-3 cm in width.

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