A heparin sodium ultrafiltration concentration device

Abstract

This invention belongs to the technical field of heparin sodium concentration mechanisms, specifically a heparin sodium ultrafiltration concentration device, including a cylinder and a cover; an ultrafiltration disc located inside the cylinder, containing inner and outer layered ultrafiltration membrane assemblies to form an annular chamber for solution diversion, with the innermost ultrafiltration membrane assemblies intercepting overflowing molecules; and a diversion mechanism located below the cover, with multiple levers arranged sequentially from the inside out, the levers being located on the outer side of a conical frame, and the inner surface of each lever being an arc-shaped surface that fits against the outer wall of the ultrafiltration membrane assemblies. This invention, through its annular ultrafiltration concentration structure combined with actively diverting levers, can guide the solution to different areas through the ultrafiltration membrane during ultrafiltration concentration. This avoids premature saturation in local areas, ensuring sufficient utilization of different areas, and also forms multi-stage interception, preventing the concentration of molecules of different molecular weights in a fixed area, thus preventing further blockage.

Description

Technical Field

[0001] This utility model belongs to the technical field of heparin sodium concentration mechanism, and in particular relates to a heparin sodium ultrafiltration concentration device. Background Technology

[0002] Heparin sodium ultrafiltration concentration is a process that uses ultrafiltration technology to concentrate and purify heparin sodium solution. Using an ultrafiltration membrane with a specific pore size, water and small molecule impurities (especially salts) in the heparin sodium solution are removed by passing through the membrane under pressure, while the larger molecular weight heparin sodium is retained. This separation and purification technique aims to increase the concentration of heparin sodium and remove small molecule impurities (desalination).

[0003] Currently, in the ultrafiltration concentration process, the solution is input through a fixed inlet, causing the ultrafiltration membrane in this area to become saturated prematurely compared to other areas due to differences in retention capacity. This leads to clogging and affects the quality and efficiency of ultrafiltration concentration.

[0004] To address the aforementioned issues, this application proposes a heparin sodium ultrafiltration concentration device. Utility Model Content

[0005] The purpose of this invention is to provide a heparin sodium ultrafiltration concentration device, which solves the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, this utility model is achieved through the following technical solution:

[0007] This utility model is a heparin sodium ultrafiltration concentration device, including a cylinder body and a cylinder cover;

[0008] The ultrafiltration disc, located inside the cylinder, contains inner and outer layers of ultrafiltration membranes to form an annular chamber for solution distribution. The innermost layer of ultrafiltration membranes is used to intercept overflowing molecules.

[0009] The diversion mechanism is located below the cylinder cover and has multiple paddles arranged sequentially from the inside to the outside. The paddles are located on the outside of the conical frame, and the inner side of the paddles is an arc-shaped surface that fits against the outer wall of the ultrafiltration membrane module.

[0010] Preferably, a conical frame is fixedly connected between the inner and outer cylinders of the ultrafiltration disc, and the ultrafiltration membrane assembly is fixed above the conical frame.

[0011] Preferably, the conical frame is a conical structure with a higher outer edge and a lower inner edge, and the upper end of the inner cylinder of the conical frame connects with the conical frame and the ultrafiltration membrane assembly.

[0012] Preferably, a bracket is fixed to the inner side of the cylinder body to support the conical frame.

[0013] Preferably, a rotating disk is rotatably mounted on the lower end of the cylinder cover, located above the adjacent ultrafiltration membrane module.

[0014] Preferably, a connecting rod is fixed between the upper end of the paddle and the paddle.

[0015] Preferably, the lower end of the paddle extends obliquely in the direction of rotation to a position adjacent to the upper surface of the conical frame.

[0016] This utility model has the following beneficial effects:

[0017] This invention forms a ring-shaped ultrafiltration concentration group by combining a paddle and an ultrafiltration membrane group. Under the rotation of the paddle, the solution passes through the ultrafiltration membrane group in different areas for ultrafiltration concentration. This not only avoids the pre-saturation and blockage caused by ultrafiltration concentration at a fixed inlet, but also increases the area of ​​the ultrafiltration membrane group, thereby improving the overall working time and making it suitable for ultrafiltration concentration of large quantities of solution.

[0018] The ultrafiltration membrane module of this invention is arranged in layers with the inner and outer conical frame to form multiple annular chambers, thereby performing multi-stage ultrafiltration concentration treatment on molecules of different molecular weights in the solution. This not only avoids the accumulation of molecules of different molecular weights that exacerbate clogging, but also prevents the innermost conical frame from becoming saturated and overflowing, which would directly affect the quality of the treated solution.

[0019] Of course, any product implementing this utility model does not necessarily need to achieve all of the advantages described above at the same time. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a structural diagram showing the overall appearance of the present invention in an exploded state;

[0022] Figure 2 This is a structural diagram showing the overall appearance of the present invention in its combined state;

[0023] Figure 3 This is a schematic diagram of the internal planar structure of the cylinder of this utility model;

[0024] Figure 4 This is a schematic diagram of the inner side structure of the cover of this utility model;

[0025] The attached diagram lists the components represented by each number as follows:

[0026] In the picture:

[0027] 11. Shell body; 111. Bracket; 12. Shell cover; 13. Ultrafiltration disc; 131. Conical frame; 132. Ultrafiltration membrane module; 14. Diverter mechanism; 141. Rotary disc; 142. Paddle; 1421. Connecting rod. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] In the description of this utility model, it should be understood that the terms "opening", "top and bottom", "thickness", "top", "middle", "length", "inner" and "around" indicate the orientation or positional relationship only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0030] Please see Figure 1-4 As shown, this utility model is a heparin sodium ultrafiltration concentration device, including a cylinder body 11 and a cylinder cover 12;

[0031] The ultrafiltration disk 13 is located inside the cylinder 11 and has an inner cylinder and an outer cylinder. The inner cylinder extends downward and the outer cylinder extends upward. The ultrafiltration disk 13 is provided with annular ultrafiltration membrane groups 132 with inner and outer layers to form annular chambers to split the solution, so that the solution passes through the ultrafiltration membrane group 132 in different areas. The innermost ultrafiltration membrane group 132 is an additional mechanism used to intercept molecules that overflow after the adjacent layer is saturated. The ultrafiltration membrane group 132 is a collection membrane group composed of multiple ultrafiltration membranes.

[0032] The diversion mechanism 14 is located below the cylinder cover 12. Multiple paddles 142 are arranged sequentially from the inside to the outside, extending into the interior of the annular chamber. The paddles 142 are located on the outside of the conical frame 131 and are used to push the solution into different areas of the annular chamber when rotating. The inner surface of the paddles 142 is an arc-shaped surface that fits against the outer wall of the ultrafiltration membrane module 132 to increase the contact surface when pushing the solution and prevent the solution from leaking directly between the arc-shaped surface and the outer wall of the ultrafiltration membrane module 132.

[0033] Furthermore, a conical frame 131 with an outer high and inner low structure is fixedly connected between the upper end of the inner cylinder and the lower end of the outer cylinder of the ultrafiltration disc 13. This frame is used to promote the flow of the solution to the inner ring area and finally into the inner cylinder, where it is stored in the bottom cavity of the cylinder body 11.

[0034] The ultrafiltration membrane module 132 is fixed above the conical frame 131. After the ultrafiltration membrane module 132 becomes clogged, it can be disassembled along with the ultrafiltration disc 13 for cleaning or replacement. The upper end of the inner cylinder of the conical frame 131 connects with the conical frame 131 and the ultrafiltration membrane module 132. A bracket 111 is fixed on the inner side of the cylinder 11 to support the conical frame 131.

[0035] Furthermore, a rotating disk 141 is rotatably mounted on the lower end of the cover 12, which is driven to rotate by a rotating motor at the upper end of the cover 12. The rotating disk 141 is located above the adjacent ultrafiltration membrane module 132 and is used to prevent the solution from directly passing over the ultrafiltration membrane module 132 and entering the next annular chamber.

[0036] Among them, a connecting rod 1421 is fixed between the upper end of the paddle 142 and the paddle 142 to fix the paddle 142, and the rotating disk 141 can be removed along with the cylinder cover 12.

[0037] In addition, the lower end of the paddle 142 extends obliquely in the direction of rotation to the position of the upper surface of the conical frame 131, forming an upward guiding force when rotating, so that the solution enters the adjacent upper region of the ultrafiltration membrane module 132, making full use of the gaps in different regions for ultrafiltration concentration.

[0038] It is understood that this utility model, through the annular arrangement of the ultrafiltration concentration structure and the combination of the active diversion lever 142, can drive the solution to different areas through the ultrafiltration concentration membrane during ultrafiltration concentration. This can not only avoid premature saturation of local areas to ensure full utilization of different areas, but also form multi-stage retention to avoid the aggravation of blockage caused by the concentration of molecules of different molecular weights in fixed areas.

[0039] A specific application of the operation process in this embodiment is as follows: During use, an annular chamber is formed between the annularly arranged ultrafiltration membrane assembly 132 and the annular wall of the ultrafiltration disk 13, so that the incoming solution is diverted to different areas of the annular chamber and passes evenly through the conical frame 131. By utilizing the different gaps of the inner and outer layers of the conical frame 131, molecules of different molecular weights are sequentially intercepted from the outside to the inside, thereby forming a multi-stage ultrafiltration concentration process. The innermost conical frame 131 is an additional component used to intercept the intercepted molecules that overflow after the adjacent layer is saturated, thereby ensuring the purity of the collected solution. During solution ultrafiltration concentration, the rotation of the rotating disk 141 drives the paddle 142 to move the solution around the conical frame 131, pushing the static solution into a dynamic state, making it easier to pass through the conical frame 131. At the same time, it can also avoid the situation where blockage in some areas directly affects the passage of subsequent solutions.

[0040] In the description of this specification, references to terms such as "an embodiment," "example," and "specific example" indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0041] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A heparin sodium ultrafiltration concentration device, characterized in that: Includes the cylinder body (11) and the cylinder cap (12); The ultrafiltration disk (13) is located inside the cylinder (11) and is equipped with an inner and outer layer of ultrafiltration membrane group (132) to form an annular chamber for distributing the solution. The innermost ultrafiltration membrane group (132) is used to intercept the overflowing molecules. The diversion mechanism (14) is located below the cylinder cover (12) and has multiple paddles (142) arranged sequentially from the inside to the outside. The paddles (142) are located on the outside of the conical frame (131), and the inner side of the paddles (142) is an arc-shaped surface that fits against the outer wall of the ultrafiltration membrane assembly (132).

2. The heparin sodium ultrafiltration concentration apparatus according to claim 1, characterized in that: A conical frame (131) is fixedly connected between the inner and outer cylinders of the ultrafiltration disc (13), and the ultrafiltration membrane assembly (132) is fixed above the conical frame (131).

3. The heparin sodium ultrafiltration concentration apparatus according to claim 2, characterized in that: The conical frame (131) is a conical structure with a higher outer edge and a lower inner edge. The upper end of the inner cylinder of the conical frame (131) is connected to the conical frame (131) and the ultrafiltration membrane assembly (132).

4. The heparin sodium ultrafiltration concentration apparatus according to claim 2, characterized in that: A bracket (111) is fixed to the inner side of the cylinder (11) to support the conical frame (131).

5. The heparin sodium ultrafiltration concentration apparatus according to claim 1, characterized in that: A rotating disk (141) is rotatably mounted on the lower end of the cap (12), located above the adjacent ultrafiltration membrane module (132).

6. The heparin sodium ultrafiltration concentration apparatus according to claim 5, characterized in that: A connecting rod (1421) is fixed between the upper end of the paddle (142) and the paddle (142).

7. The heparin sodium ultrafiltration concentration apparatus according to claim 2, characterized in that: The lower end of the paddle (142) extends obliquely in the direction of rotation to the position of the upper surface of the adjacent conical frame (131).

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