A device for refining ramelteon bulk drug

CN224388108UActive Publication Date: 2026-06-23JINGHUA PHARMA GRP NANTONG
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Patent Information

Application Number
CN202521393628.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-07-04
Publication Date
2026-06-23
Estimated Expiration
2035-07-04

AI Technical Summary

Technical Problem

In existing refining equipment for ramelteamide active pharmaceutical ingredient (API), API crystals tend to adhere to the inner wall of the container and the stirring structure, resulting in reduced crystal volume and difficulty in cleaning.

Method used

A refining device including a clamping mechanism, a stirring mechanism, and a striking mechanism was designed. The combination of heating with an electric heating plate, stirring with stirring blades, and striking with a striking plate ensures that the crystals are fully scraped and removed.

Benefits of technology

It effectively improves the mixing degree of active pharmaceutical ingredients and the crystallization extraction rate, reduces adhesion residues, and simplifies the cleaning process.

✦ Generated by Eureka AI based on patent content.

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Abstract

This utility model relates to the field of active pharmaceutical ingredient (API) refining technology, and in particular to a refining device for ramelteline API. The device includes a housing, a first electric push rod at the top of the housing, an inlet / outlet groove at the bottom of the housing, clamping mechanisms on both sides of the housing's interior, a holding cylinder clamped in the middle of the clamping mechanisms, a stirring mechanism inside the holding cylinder, and a striking mechanism on one side of the top of the stirring mechanism. The clamping mechanisms include a second electric push rod and a clamping plate. The second electric push rod is horizontally fixed on both sides of the housing's interior. The advantages are: this utility model uses striking vibration to vibrate the stirring blades, thereby vibrating and removing API crystals adhering to the surface of the stirring blades and the inner surface of the holding cylinder, reducing the amount of residual API crystals; it facilitates the placement and removal of the holding cylinder, and facilitates the thorough removal and cleaning of API crystals inside the holding cylinder.
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Citation Information

Patent Citations

  • Refining equipment for raw material medicine

    CN220530717U