Biochemical diagnosis reagent mixing device
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 潍坊三维生物工程集团有限公司
- Filing Date
- 2025-07-14
- Publication Date
- 2026-06-26
AI Technical Summary
In existing technologies, mixing devices for biochemical diagnostic reagents suffer from problems such as complex structure, high cost, and uneven mixing, which cannot meet the needs of primary healthcare institutions.
A biochemical diagnostic reagent mixing device was designed, which adopts independent reagent and additive inlets and combines components such as a spiral guide plate, stirring shaft, auger blades, temperature control chamber, electric heating plate and ultrasonic vibrator to ensure that the reagents are mixed in a closed environment. The mixing uniformity and efficiency are improved by spiral flow, turbulence and circulation.
It enables precise addition and mixing of reagents and additives, ensuring the stability and uniformity of the mixing process, improving mixing efficiency and device convenience, and meeting the needs of primary healthcare institutions.
Smart Images

Figure CN224404977U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of diagnostic reagent production technology, specifically to a biochemical diagnostic reagent mixing device. Background Technology
[0002] In clinical biochemical testing, the precise mixing of multiple reagents is crucial for ensuring accurate test results. Traditional manual mixing methods suffer from problems such as large operational errors, low efficiency, and susceptibility to contamination; while existing automated mixing equipment generally suffers from drawbacks such as complex structure, high cost, and uneven mixing, failing to meet the actual needs of primary healthcare institutions. Therefore, there is an urgent need for a biochemical diagnostic reagent mixing device that is simple in structure, provides good mixing performance, and is cost-effective. Summary of the Invention
[0003] The technical problem to be solved by this utility model is to provide a biochemical diagnostic reagent mixing device that is simple in structure, has good mixing effect and low cost, in order to address the shortcomings of the existing technology.
[0004] To solve the above-mentioned technical problems, the technical solution of this utility model is as follows:
[0005] A biochemical diagnostic reagent mixing device includes an outer shell with a reagent inlet and an additive inlet at the top. The outer shell has a mixing chamber inside and an outlet at the bottom that extends through the mixing chamber. A stirring shaft is located inside the mixing chamber. A first fixed seat is located in the middle section of the stirring shaft. Several stirring blades are arranged circumferentially around the first fixed seat. A fixing rod is located between adjacent stirring blades. One end of the fixing rod is connected to the first fixed seat, and the other end is connected to a conical flow guide.
[0006] As an improved technical solution, the wall of the mixing chamber is provided with a spiral guide plate.
[0007] As an improved technical solution, the pitch of the spiral guide plate gradually decreases from the top to the bottom of the mixing chamber.
[0008] As an improved technical solution, the cone bottom of the flow guide is positioned facing the inner wall of the mixing chamber.
[0009] As an improved technical solution, the upper and lower sections of the stirring shaft are respectively equipped with auger blades.
[0010] As an improved technical solution, the bottom of the stirring shaft is provided with a second fixed seat, the second fixed seat is provided with a plurality of connecting rods in the circumference, and the end of the connecting rod is provided with a U-shaped stirring head.
[0011] As a preferred technical solution, the outer shell is provided with a temperature control cavity.
[0012] As a preferred technical solution, the outer shell is provided with an electric heating plate at the lower part of the mixing chamber.
[0013] As a preferred technical solution, the bottom of the mixing chamber is provided with several ultrasonic vibrators.
[0014] Due to the adoption of the above technical solution, the beneficial effects of this utility model are:
[0015] This biochemical diagnostic reagent mixing device, through its independently designed reagent and additive inlets, enables the separate addition of reagents and additives. This avoids inaccurate proportions or uneven mixing caused by pre-mixing during the initial addition process, ensuring accuracy in the initial addition stage. Simultaneously, the mixing chamber provides a dedicated mixing space for reagents and additives, ensuring the mixing process takes place in a relatively closed and stable environment, reducing interference from external factors. The lower outlet facilitates the smooth discharge of the mixed reagents. The entire structural design conforms to the flow logic of mixing operations, improving the ease of use and reliability of the mixing process. When the stirring shaft drives the stirring blades to rotate, it directly stirs the reagents and additives within the mixing chamber, breaking the static state of the materials and promoting initial mixing. The conical flow guide shroud guides the surrounding materials during stirring. As materials flow through the shroud, they are guided in different directions by the conical surface, increasing the flow path and turbulence, further enhancing the disturbance effect and preventing the formation of stagnant or slow-flowing dead zones in local areas, thereby improving the overall uniformity and efficiency of the mixing.
[0016] The mixing chamber wall is equipped with spiral guide plates. These plates guide the material within the mixing chamber along a spiral path. When the material flows under stirring, it is constrained and guided by the guide plates, forming an orderly spiral upward or downward motion, increasing the distance and time the material travels within the mixing chamber. This spiral flow not only ensures sufficient contact between materials but also promotes the exchange and mixing of materials in different areas, avoiding insufficient mixing caused by materials circulating only in a localized area, thus effectively improving the mixing effect.
[0017] The pitch of the spiral guide plate gradually decreases from the top to the bottom of the mixing chamber. This change in pitch ensures a relatively gentle spiral path as the material flows at the top of the mixing chamber, allowing sufficient space and time for the reagents and additives to undergo initial diffusion and contact upon entering the chamber. As the material flows downwards, the pitch gradually decreases, the spiral path becomes more compact, and the flow velocity and turbulence of the material gradually increase, resulting in more thorough and vigorous mixing during its downward movement. This gradually changing pitch design meets the progressive requirements of the material mixing process, transitioning gradually from initial mixing to deep mixing, further improving the uniformity and thoroughness of the mixing.
[0018] The conical bottom of the flow guide is positioned facing the inner wall of the mixing chamber. When the flow guide rotates with the stirring shaft, the conical bottom facing the inner wall guides the material towards the inner wall of the mixing chamber, causing the material to collide with the chamber wall and bounce back, forming more turbulence and eddies. These turbulence and eddies can break the original flow state of the material, promote mutual penetration and mixing between materials, and at the same time avoid excessive accumulation of material in the central area of the mixing chamber, which would lead to uneven mixing. This ensures that the material near the chamber wall is also fully mixed, improving the overall mixing effect.
[0019] The stirring shaft is equipped with auger blades at both the upper and lower sections. These auger blades transport materials; the upper blades convey materials from the upper part of the mixing chamber upwards or downwards, while the lower blades convey materials from the lower part, creating a circulating flow of materials within the mixing chamber. This circulation allows materials at different heights within the mixing chamber to continuously exchange positions, preventing stratification due to gravity and ensuring uniform mixing of materials at both the upper and lower levels. Simultaneously, the conveying action of the auger blades enhances the overall flowability of the materials, improving mixing efficiency.
[0020] The bottom of the stirring shaft is provided with a second fixed seat, and the second fixed seat is circumferentially provided with several connecting rods. The ends of the connecting rods are provided with U-shaped stirring heads. The U-shaped stirring heads at the bottom of the stirring shaft can perform targeted stirring of the material at the bottom of the mixing chamber. Due to gravity, some material may settle at the bottom of the mixing chamber. When the U-shaped stirring heads rotate, they can penetrate deep into the bottom material and cut, turn, and stir the material through their unique shape, effectively preventing the material from settling and clumping at the bottom. This ensures that the bottom material can be fully mixed with the upper material, improving the comprehensiveness and uniformity of the mixing.
[0021] The outer casing is equipped with a temperature-controlled chamber. This chamber allows for temperature regulation and control of the mixing chamber by introducing media of different temperatures (such as hot water, cold water, or a constant-temperature liquid). In the mixing process of biochemical diagnostic reagents, the activity and stability of many reagents are highly sensitive to temperature. A suitable temperature environment ensures that the performance of the reagents is not affected, guaranteeing the smooth progress of the mixing reaction. The temperature-controlled chamber allows for precise temperature control of the mixing chamber according to actual needs, providing stable temperature conditions for reagent mixing and improving the reliability and accuracy of the mixing reaction.
[0022] The outer casing is equipped with an electric heating plate at the lower part of the mixing chamber. This electric heating plate directly heats the material in the lower part of the mixing chamber, providing a direct and efficient heating method that rapidly raises the material's temperature. For reagents requiring mixing at specific temperatures, the electric heating plate can quickly heat the material to the required temperature and maintain a stable temperature through a temperature control device. Simultaneously, heating from the bottom up utilizes the principle of thermal convection, ensuring a uniform temperature rise within the mixing chamber. This avoids damage to the reagents caused by localized overheating or uneven temperature distribution, guaranteeing that the mixing reaction proceeds under suitable temperature conditions.
[0023] The bottom of the mixing chamber is equipped with several ultrasonic vibrators. The ultrasonic waves generated by these vibrators induce high-frequency vibrations within the material. These vibrations cause strong collisions and friction between material molecules, thereby breaking down intermolecular forces and promoting dissolution and dispersion. For reagents that are difficult to mix or additives containing fine particles, ultrasonic vibration can effectively disperse them uniformly, preventing particle agglomeration. Simultaneously, ultrasonic vibration enhances the flowability of the material, working synergistically with stirring and other mixing methods to further improve the mixing speed and uniformity, ensuring that the quality of the mixed reagent meets the requirements for biochemical diagnostics. Attached Figure Description
[0024] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0025] Figure 1 This is a structural schematic diagram of an embodiment of the present utility model;
[0026] Figure 2 This is a cross-sectional view of an embodiment of the present utility model;
[0027] Figure 3 yes Figure 2 Schematic diagram of the structure of the stirring shaft;
[0028] Figure 4 yes Figure 2 A schematic diagram of the structure of the stirring blades and the flow guide;
[0029] Figure 5 yes Figure 2Schematic diagram of the structure of the stirring head;
[0030] The components are as follows: 1. Outer shell; 2. Reagent inlet; 3. Additive inlet; 4. Mixing chamber; 5. Discharge port; 6. Stirring shaft; 7. First fixed seat; 8. Stirring blades; 9. Fixed rod; 10. Flow guide shroud; 11. Spiral flow guide plate; 12. Screwdriver blades; 13. Second fixed seat; 14. Connecting rod; 15. Stirring head; 16. Temperature control chamber; 17. Electric heating plate; 18. Ultrasonic vibrator. Detailed Implementation
[0031] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0032] like Figure 1-5 As shown, a biochemical diagnostic reagent mixing device includes a housing 1. The top of the housing is provided with a reagent inlet 2 and an additive inlet 3. The independently located reagent inlet 2 and additive inlet 3 allow for the separate addition of reagents and additives, avoiding inaccurate proportions or uneven mixing caused by pre-mixing during the addition process, thus ensuring accuracy in the initial addition stage. Simultaneously, a mixing chamber 4 provides a dedicated mixing space for reagents and additives, ensuring the mixing process takes place in a relatively closed and stable environment, reducing interference from external factors. The discharge port 5 at the bottom facilitates the smooth discharge of the mixed reagents. The entire structural design conforms to the process logic of mixing operations, improving the convenience of use and the reliability of mixing. When the stirring shaft 6 drives the stirring blades 8 on the outside of the first fixed seat 7 to rotate, it directly stirs the reagents and additives in the mixing chamber 4, breaking the static state of the materials and promoting initial mixing. The conical guide shroud 10 connected to the fixed rod 9 will guide the surrounding materials during the stirring process. When the materials flow through the guide shroud 10, they will be guided by the conical surface of the guide shroud 10 to flow in different directions, which increases the flow path and turbulence of the materials, further enhancing the disturbance effect on the materials, and avoiding the formation of dead zones where the materials are stationary or flow slowly in local areas, thereby improving the overall uniformity and efficiency of mixing.
[0033] The mixing chamber 4 is equipped with a spiral guide plate 11 on its wall. The spiral guide plate 11 guides the material within the mixing chamber 4 to flow along a spiral path. When the material flows under stirring, it is constrained and guided by the guide plate, forming an orderly spiral upward or downward motion, increasing the distance and time the material travels within the mixing chamber 4. This spiral flow not only ensures sufficient contact between materials but also promotes the exchange and mixing of materials in different areas, avoiding insufficient mixing caused by materials circulating only in a localized area, thus effectively improving the mixing effect.
[0034] The pitch of the spiral guide plate gradually decreases from the top to the bottom of the mixing chamber 4. This change in pitch ensures a relatively gentle spiral path as the material flows at the top of the mixing chamber 4, allowing sufficient space and time for the reagents and additives entering the chamber to undergo initial diffusion and contact. As the material flows downwards, the pitch gradually decreases, the spiral path becomes more compact, and the flow velocity and turbulence of the material gradually increase, resulting in more thorough and vigorous mixing during its downward movement. This gradual pitch design meets the progressive requirements of the material mixing process, transitioning gradually from initial mixing to deep mixing, further improving the uniformity and thoroughness of the mixing.
[0035] The conical bottom of the flow guide shroud 10 faces the inner wall of the mixing chamber 4. When the flow guide shroud 10 rotates with the stirring shaft 6, the conical bottom facing the inner wall guides the material towards the inner wall of the mixing chamber 4, causing the material to collide with the chamber wall and bounce back, forming more turbulence and eddies. These turbulence and eddies can break the original flow state of the material, promote mutual penetration and mixing between materials, and at the same time avoid the uneven mixing caused by excessive accumulation of materials in the central area of the mixing chamber 4, allowing the material near the chamber wall to be fully mixed as well, thus improving the overall mixing effect.
[0036] The stirring shaft 6 is equipped with auger blades 12 at both its upper and lower sections. The auger blades 12 function to convey materials; the upper auger blades 12 convey materials from the upper part of the mixing chamber 4 upwards or downwards, while the lower auger blades 12 convey materials from the lower part, thus creating a circulating flow of materials within the mixing chamber 4. This circulating flow allows materials at different heights within the mixing chamber 4 to continuously exchange positions, preventing stratification due to gravity and ensuring uniform mixing of materials at both the upper and lower levels. Simultaneously, the conveying function of the auger blades 12 enhances the overall flowability of the materials, improving mixing efficiency.
[0037] The bottom of the stirring shaft 6 is provided with a second fixed seat 13, and the second fixed seat 13 is provided with a plurality of connecting rods 14 around its circumference. The ends of the connecting rods 14 are provided with U-shaped stirring heads 15. The U-shaped stirring heads 15 at the bottom of the stirring shaft 6 can perform targeted stirring of the material at the bottom of the mixing chamber 4. Due to gravity, some material may settle at the bottom of the mixing chamber 4. When the U-shaped stirring heads 15 rotate, they can penetrate into the bottom material and cut, turn and stir the material through their unique shape, effectively preventing the material from settling and clumping at the bottom, ensuring that the bottom material can be fully mixed with the upper material, and improving the comprehensiveness and uniformity of the mixing.
[0038] The outer casing 1 is equipped with a temperature control chamber 16. The temperature control chamber 16 can regulate and control the temperature of the mixing chamber 4 by introducing media of different temperatures (such as hot water, cold water, or a constant-temperature liquid). During the mixing of biochemical diagnostic reagents, the activity and stability of many reagents are highly sensitive to temperature. A suitable temperature environment ensures that the performance of the reagents is not affected, guaranteeing the smooth progress of the mixing reaction. The temperature control chamber 16 allows for precise temperature control of the mixing chamber 4 according to actual needs, providing stable temperature conditions for reagent mixing and improving the reliability and accuracy of the mixing reaction.
[0039] The outer casing 1 is equipped with an electric heating plate 17 at the lower part of the mixing chamber 4. The electric heating plate 17 can directly heat the material in the lower part of the mixing chamber 4, providing a direct and efficient heating method that can quickly raise the temperature of the material. For reagents that need to be mixed at a specific temperature, the electric heating plate 17 can quickly heat the material to the required temperature and maintain a stable temperature through a temperature control device. Simultaneously, heating from the bottom up utilizes the principle of heat convection to ensure a uniform temperature rise in the material within the mixing chamber 4, avoiding damage to the reagents caused by localized overheating or uneven temperature distribution, and ensuring that the mixing reaction proceeds under suitable temperature conditions.
[0040] The bottom of the mixing chamber 4 is equipped with several ultrasonic vibrators 18. The ultrasonic waves generated by the ultrasonic vibrators 18 can produce high-frequency vibrations in the material. This vibration causes strong collisions and friction between material molecules, thereby breaking the intermolecular forces between the materials and promoting the dissolution and dispersion of the materials. For some reagents that are difficult to mix or additives containing small particles, ultrasonic vibration can effectively disperse them evenly and prevent particle agglomeration. At the same time, ultrasonic vibration can also enhance the flowability of the material, working synergistically with mixing methods such as stirring to further improve the mixing speed and uniformity, ensuring that the quality of the mixed reagent meets the requirements of biochemical diagnostics.
[0041] It should be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that after reading the teachings of this invention, those skilled in the art can make various alterations or modifications to the invention, and these equivalent forms also fall within the scope defined by the appended claims.
Claims
1. A biochemical diagnostic reagent mixing device, comprising a housing, wherein a reagent inlet and an additive inlet are respectively provided at the top of the housing, a mixing chamber is provided inside the housing, and a discharge port penetrating the mixing chamber is provided at the bottom of the housing, characterized in that: The mixing chamber is equipped with a stirring shaft, and the middle section of the stirring shaft is equipped with a first fixed seat. The first fixed seat is equipped with a plurality of stirring blades around its circumference. A fixed rod is provided between two adjacent stirring blades. One end of the fixed rod is connected to the first fixed seat, and the other end of the fixed rod is connected to a conical guide shroud.
2. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The mixing chamber is equipped with a spiral guide plate on its wall.
3. The biochemical diagnostic reagent mixing device as described in claim 2, characterized in that: The pitch of the spiral guide plate gradually decreases from the top to the bottom of the mixing chamber.
4. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The cone bottom of the flow guide is positioned facing the inner wall of the mixing chamber.
5. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The upper and lower sections of the stirring shaft are respectively equipped with auger blades.
6. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The bottom of the stirring shaft is provided with a second fixed seat, and the second fixed seat is provided with a plurality of connecting rods in the circumference, and the end of the connecting rod is provided with a U-shaped stirring head.
7. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The outer shell is provided with a temperature control cavity.
8. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The outer casing is equipped with an electric heating plate at the lower part of the mixing chamber.
9. The biochemical diagnostic reagent mixing device as described in claim 1, characterized in that: The bottom of the mixing chamber is equipped with several ultrasonic vibrators.