Simple mixing and uniform moisturizing box
By designing a simple, mixable, and moisturizing box, the problems of insufficient contact between the reaction solution and tissue and difficulty in identifying the number of slides caused by the inability to tilt the slide holder were solved, thus achieving thorough mixing of the reaction solution and rapid recording of the number of slides.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 175TH HOSPITAL OF PEOPLES LIBERATION ARMY
- Filing Date
- 2025-08-01
- Publication Date
- 2026-06-26
AI Technical Summary
The slide holders in existing immunohistochemistry humidifiers cannot be tilted, resulting in insufficient contact between the reaction solution and the tissue, incomplete rinsing, and the lack of labeling makes it difficult to quickly determine the number of slides, affecting subsequent recording.
A simple, mixable, and humidified box was designed, comprising a fixed shelf, a movable shelf, an adjustment mechanism, and digital labels. By adjusting the angle of the movable shelf, the slide can be tilted to enhance the contact between the reaction solution and the tissue, and the digital labels facilitate the identification and recording of the number of sections.
It achieves full contact between the reaction solution and the tissue, improves the mixing effect, reduces non-specific expression, and can quickly identify the number of sections, making it easy to record accurately.
Smart Images
Figure CN224416545U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical experimental instrument technology, specifically a simple, mixable, and humidifying box. Background Technology
[0002] An immunohistochemistry humidifier is a type of medical laboratory instrument and a commonly used tool in immunohistochemistry (IHC) experiments. It is mainly used to maintain a moist environment for tissue sections or cell samples during antibody incubation, prevent reagents from drying out, and ensure the stability and reliability of experimental results.
[0003] A search revealed that the announcement number is CN213633452U, and the name is an immunohistochemistry humidified chamber, which includes a box body and a lid. Through research and analysis, it was found that although compared with the previous single-layer immunohistochemistry humidified chamber, the upper space is utilized more efficiently, more slides can be placed, and the slides are easier to put in and take out, it still has the following drawbacks to some extent.
[0004] For example, the slide holders in the aforementioned immunohistochemistry humidifiers are all fixedly installed, making it impossible to tilt the slides by rotating the slide holders. The slides are always placed horizontally, which makes it impossible to thoroughly rinse away unbound reaction solution. At the same time, the inability to rotate the slide holders back and forth results in insufficient contact between the reaction solution and the tissue. Furthermore, the lack of markings on the bottom of the box makes it difficult for personnel to quickly understand the number of slides, which is not conducive to subsequent recording of each slide. In order to solve the above technical problems, we designed a simple mixing and humidifying box. Utility Model Content
[0005] The purpose of this invention is to provide a simple, mixing, and moisturizing box with adjustable slide angles, which allows the reaction solution to fully contact the tissue and facilitates the rinsing of unbound reaction solution, reducing non-specific expression. It also makes the number of slides in the box readily apparent and easy to record. This invention solves the problems of fixed slide placement, which hinders full contact between the reaction solution and tissue, resulting in poor mixing, incomplete rinsing, lack of labeling, and inability to quickly determine the number of slides, thus hindering subsequent recording.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a simple mixing and moisturizing box, comprising a box body, wherein a fixed shelf, a limiting baffle, and a movable shelf are respectively installed in the inner cavity of the box body, and a locking block is fixedly connected to the top of the fixed shelf and the movable shelf, and a rotating rod is fixedly connected to the left and right sides of the movable shelf, wherein the outer side of the rotating rod on the right side penetrates the box body and is fixedly connected to an adjustment mechanism, a number is fixedly connected to the bottom of the inner cavity of the box, and a drain hole is opened on the rear side of the inner cavity of the box.
[0007] Preferably, the adjustment mechanism includes a mounting block, and an adjustment rod is slidably connected through the top of the mounting block. Limiting blocks are fixedly installed at both the top and bottom of the adjustment rod.
[0008] Preferably, there are three fixed shelves, three limiting baffles, and three movable shelves, and the bottom of each of the fixed shelves and the movable shelves is provided with a flow hole.
[0009] Preferably, a rubber plug is inserted into the rear side of the drain hole, and the surface of the rotating rod is slidably connected to the box body.
[0010] Preferably, the surfaces of the fixed shelf and the limiting baffle are fixedly connected to the inner cavity of the box, and a rubber retaining ring is glued to the bottom right side of the box.
[0011] Preferably, limiting protrusions are fixedly connected to the front and rear sides and the middle of the left side of the inner cavity of the box, the number of the numbered identifiers is thirty, a glass slide is engaged between the two left and right locking blocks, and a top cover is fitted on the top of the box.
[0012] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0013] Gently rotate the adjusting lever back and forth, and the movable shelf will follow the rotation, causing one side of the glass slide to move up and down for adjustment. This ensures that the reaction solution comes into full contact with the tissue, achieving a shaking and mixing effect.
[0014] When rinsing the slides, tilting the slides by adjusting the movable plate helps to rinse away unbound reaction solution, which can effectively reduce non-specific expression.
[0015] Several numerical markings are set at the bottom of the inner cavity of the box. The slide plate is aligned with the numerical markings at the bottom, so that the number of slides in the box can be seen at a glance. When used with a standard staining slide holder, it is convenient to accurately record each slide. Attached Figure Description
[0016] Figure 1 This is an axonometric view of the structure of this utility model;
[0017] Figure 2 This is a top axonometric view of the box body of this utility model;
[0018] Figure 3 This utility model Figure 1 Enlarged view of A in the middle;
[0019] Figure 4 This is an isometric view of the movable shelf and adjustment mechanism of this utility model;
[0020] Figure 5 This is a rear axonometric view of the new type of housing.
[0021] Figure 6 This is a top axonometric view of the box body and top cover of this utility model.
[0022] In the diagram: 1. Box body; 2. Glass slide plate; 3. Fixed shelf; 4. Limiting protrusion; 5. Movable shelf; 6. Limiting baffle; 7. Locking block; 8. Adjusting mechanism; 9. Rubber retaining ring; 10. Number marking; 11. Rubber plug; 12. Flow hole; 13. Rotating rod; 14. Drain hole; 15. Mounting block; 16. Adjusting rod; 17. Limiting baffle; 18. Top cover. Detailed Implementation
[0023] Please see Figures 1-6 A simple, easily mixed, moisturizing box includes a box body 1. The inner cavity of the box body 1 is respectively equipped with a fixed shelf 3, a limiting baffle 6, and a movable shelf 5. The top of the fixed shelf 3 and the movable shelf 5 are fixedly connected with a locking block 7. There are several locking blocks 7, which are arranged in pairs to separate glass slides. The left and right sides of the movable shelf 5 are fixedly connected with rotating rods 13. The outer side of the rotating rod 13 on the right side passes through the box body 1 and is fixedly connected with an adjustment mechanism 8. The bottom of the inner cavity of the box body 1 is fixedly connected with a number 10, which is a number from 1 to 30. A drain hole 14 is opened on the rear side of the inner cavity of the box body 1. By setting the drain hole 14, when there is a lot of rinsing liquid stored in the box body 1, the liquid in the moisturizing box can be drained through this hole.
[0024] Please see Figure 4 The adjustment mechanism 8 includes a mounting block 15, and an adjustment rod 16 is slidably connected through the top of the mounting block 15. Limiting blocks 17 are fixedly installed at the top and bottom of the adjustment rod 16. By setting the mounting block 15, the adjustment rod 16 can be slidably installed to move up and down. By setting the limiting blocks 17, the adjustment rod 16 can be prevented from detaching from the mounting block 15.
[0025] Please see Figure 2 There are three fixed shelves 3, three limiting baffles 6 and three movable shelves 5. One fixed shelf 3 and one movable shelf 5 form a group. By setting the limiting baffles 6, the glass slide 2 can be limited to prevent it from falling into the box during tilting. The bottom of both the fixed shelf 3 and the movable shelf 5 is provided with a liquid flow hole 12. By setting the liquid flow hole 12, the moisturizing liquid can flow into each tank through this hole.
[0026] Please see Figure 4 and Figure 5 A rubber plug 11 is inserted into the rear side of the drain hole 14. By setting the rubber plug 11, the drain hole 14 can be easily blocked to control the liquid flow. The surface of the rotating rod 13 is slidably connected to the box body 1.
[0027] Please see Figure 2 and Figure 3The surfaces of the fixed shelf 3 and the limiting baffle 6 are fixedly connected to the inner cavity of the box body 1. A rubber retaining ring 9 is glued to the bottom right side of the box body 1. By setting the rubber retaining ring 9, the limiting block 17 at the bottom of the adjusting rod 16 can be inserted into its interior for limiting, so as to avoid accidental contact that causes the glass slide 2 to tilt.
[0028] Please see Figure 1 Limiting protrusions 4 are fixedly connected to the front and rear sides and the middle of the left side of the inner cavity of the box body 1. By setting the limiting protrusions 4, the adjustment range of the movable shelf 5 can be limited. The adjustment angle is 0-15 degrees. There are thirty numbered 10. A glass slide 2 is locked between the two left and right locking blocks 7. A top cover 18 is fitted on the top of the box body 1.
[0029] In use, place the slide 2 on top of the fixed plate 3 and the movable plate 5 and lock it between the two side blocks 7. After placing the slides and adding the reaction solution, push the adjusting rod 16 upward and rotate it gently back and forth. The movable plate 5 will rotate accordingly, moving one side of the slide 2 up and down to adjust it, so that the reaction solution can fully contact the tissue and achieve a mixing effect. When the reaction is underway, stop rotating the adjusting rod 16 to reset the movable plate 5. The fixed plate 3 and the movable plate 5 will be horizontally aligned, which is beneficial for the reaction. When washing the slides, the movable plate 5 can be adjusted to tilt the slide 2, which is beneficial for washing away unbound reaction solution and can effectively reduce non-specific expression. Several numerical labels 10 are set at the bottom of the inner cavity of the box 1, so that each slide 2 is vertically aligned with the numerical label 10 at the bottom. This makes the number of slides in the box 1 clear at a glance. When used with a standard staining slide holder, it is convenient to accurately record each slide.
[0030] In summary, this simple mixing and humidifying box, through the coordinated use of the box body 1, fixed shelf 3, movable shelf 5, limiting baffle 6, adjustment mechanism 8, digital label 10, rotating rod 13, and drainage hole 14, solves the problems of poor mixing effect, incomplete rinsing, lack of labeling, inability to quickly understand the number of sections, and difficulties in subsequent recording caused by fixing the slides in place.
Claims
1. A simple, mixable, and humidifying box, comprising a box body (1), characterized in that: The inner cavity of the box (1) is equipped with a fixed shelf (3), a limiting baffle (6) and a movable shelf (5). The top of the fixed shelf (3) and the movable shelf (5) are fixedly connected with a locking block (7). The left and right sides of the movable shelf (5) are fixedly connected with a rotating rod (13). The outer side of the rotating rod (13) on the right side passes through the box (1) and is fixedly connected with an adjustment mechanism (8). The bottom of the inner cavity of the box (1) is fixedly connected with a number label (10). The rear side of the inner cavity of the box (1) is provided with a drain hole (14).
2. The simple, mixable, and humidifying box according to claim 1, characterized in that: The adjustment mechanism (8) includes a mounting block (15), and an adjustment rod (16) is slidably connected through the top of the mounting block (15). Limiting blocks (17) are fixedly installed at the top and bottom of the adjustment rod (16).
3. The simple, mixable, and humidifying box according to claim 1, characterized in that: The number of fixed layer plate (3), limiting baffle (6) and movable layer plate (5) are all three, and the bottom of the fixed layer plate (3) and the movable layer plate (5) are provided with flow holes (12).
4. A simple, mixable, and humidifying box according to claim 1, characterized in that: A rubber plug (11) is inserted into the rear side of the drain hole (14), and the surface of the rotating rod (13) is slidably connected to the box body (1).
5. A simple, mixable, and humidifying box according to claim 1, characterized in that: The surfaces of the fixed layer (3) and the limiting baffle (6) are fixedly connected to the inner cavity of the box body (1), and a rubber retaining ring (9) is glued to the bottom right side of the box body (1).
6. A simple, mixable, and humidifying box according to claim 1, characterized in that: Limiting protrusions (4) are fixedly connected to the front and rear sides and the middle of the left side of the inner cavity of the box (1). There are thirty digital identifiers (10). A glass slide (2) is snapped between the two left and right clips (7). A top cover (18) is fitted on the top of the box (1).