Ex vivo tissue fixation assembly

Abstract

This utility model discloses an ex vivo tissue fixation component, including an integrally formed fixation component with an arc-shaped end on one side and multiple slots on a straight end on the other side. The slots are arranged in parallel, with one end extending towards the arc-shaped end and the other end penetrating the straight end. The fixation components are sequentially engaged within a sample tube. This utility model provides an ex vivo tissue fixation component that, through its parallel slotted structure, can quickly fix ex vivo tissue in a preset position within a sample tube. This not only ensures the consistency and comparability of scan data from the same group of samples but also allows for the simultaneous processing of multiple samples in a single scan by sequentially engaging multiple fixation components within the sample tube.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to an ex vivo tissue fixation component. Background Technology

[0002] The Burker SkyScan 1276 microCT technology is widely used for morphological analysis of ex vivo samples such as bone tissue, soft tissue, organs, and biological materials due to its high resolution and non-destructive 3D imaging capabilities. However, existing scanning procedures for ex vivo tissues have the following key problems:

[0003] Ex vivo tissues are usually placed directly into sample tubes, and their position (such as rotation center offset) and orientation (such as tilt angle) depend on manual adjustment. The space utilization rate of a single sample tube is low. When placed directly, a single scan can usually only accommodate 1-2 samples, and multiple groups of samples need to be processed in batches.

[0004] In summary, there is an urgent need to design an ex vivo tissue fixation component that overcomes the aforementioned technical problems. Utility Model Content

[0005] In view of the problems mentioned in the background art, the purpose of this utility model is to provide an ex vivo tissue fixation component to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model mainly provides the following technical solutions:

[0007] An ex vivo tissue fixation component includes an integrally formed fixation component, one side of which is an arc-shaped end, and the other side has a straight end with multiple slots.

[0008] The slots are set in parallel, with one end of each slot extending toward the arc end and the other end passing through the straight end.

[0009] Each fixing component is sequentially inserted into the sample tube.

[0010] Furthermore, each fixing component has 2-5 slots;

[0011] The length of each slot is determined according to the specific circumstances.

[0012] Furthermore, it also includes an anti-slip component, which is disposed on the side wall of the arc end of the fixing component;

[0013] The anti-slip component is an anti-slip particle or an anti-slip mat.

[0014] Furthermore, it also includes a marking area, which is located on the upper and lower surfaces of the fixing component;

[0015] The marking area is embedded with waterproof writing paper.

[0016] Furthermore, the slot is V-shaped, with the opening at the near-straight end being smaller than that at the other end of the slot.

[0017] Furthermore, the fixing component is made of elastic polystyrene material.

[0018] Compared with the prior art, the beneficial effects of this utility model are mainly reflected in:

[0019] This invention provides an ex vivo tissue fixation component. By setting a parallel slotted structure, it can quickly fix the ex vivo tissue in a preset position inside the sample tube. This not only ensures the consistency and comparability of the scanning data of the same group of samples, but also allows multiple fixation components to be sequentially installed in the sample tube, enabling the simultaneous processing of multiple samples in a single scan.

[0020] This invention provides an ex vivo tissue fixation component that combines the elastic deformation capability of polystyrene material to adapt to sample tubes of different diameters, thereby improving equipment utilization and experimental efficiency.

[0021] The design of the fixing component of this invention, which is compatible with the sample tube of the Burker SkyScan 1276 microCT instrument and features customizable size, provides an efficient and flexible solution for biomedical imaging research. The efficient experimental process can greatly shorten the experimental cycle, improve research efficiency, and enable researchers to obtain more experimental data in a shorter time.

[0022] The above description is only an overview of the technical solution of this utility model. In order to clearly understand the technical means of this utility model and to implement it in accordance with the contents of the specification, the preferred embodiments of this utility model are described in detail below with reference to the accompanying drawings. Attached Figure Description

[0023] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0024] Figure 1 This is a schematic diagram of the structure of the ex vivo tissue fixation component of this utility model;

[0025] Figure 2 This is another structural schematic diagram of the ex vivo tissue fixation component of this utility model;

[0026] Figure 3This is a schematic diagram showing the usage state of the ex vivo tissue fixation component of this utility model.

[0027] Explanation of reference numerals in the attached figures:

[0028] 1. Fixed component; 11. Arc end; 12. Straight end;

[0029] 2. Grooving; 3. Anti-slip components; 4. Sample tube; 5. Marking area. Detailed Implementation

[0030] To further illustrate the technical means and effects adopted by this utility model to achieve its intended purpose, the following detailed description, in conjunction with the accompanying drawings and preferred embodiments, details the specific implementation methods, structure, features, and effects of the ex vivo tissue fixation component proposed according to this utility model.

[0031] like Figure 1-3 As shown, the present invention provides an in vitro tissue fixation component, including an integrally formed fixation component 1, one side of which is an arc-shaped end 11, and the other side has a straight end 12 with multiple slots 2. The fixation component 1 is made of polystyrene material, which has a certain deformation force, so that the fixation component 1 can automatically adjust the clamping force according to the shape and size of the in vitro tissue, thereby effectively fixing the in vitro tissue accordingly.

[0032] Each slot 2 is arranged in parallel, with one end of each slot 2 extending toward the arc end 11 and the other end passing through the straight end 12; the different slots 2 give the fixing component 1 good elasticity and flexibility. When the fixing component 1 is subjected to external force, the slots 2 can deform to a certain extent, so that the fixing component 1 can adapt to ex vivo tissues of different shapes and sizes.

[0033] Each fixing component 1 is sequentially inserted into the sample tube 4.

[0034] In practical applications, multiple such fixing components 1 are inserted into the sample tube 4 in a specific order to ensure that the tissue remains stable during subsequent experimental operations and does not move arbitrarily, thus providing a strong guarantee for the smooth progress of the experiment and the accuracy of the results.

[0035] Furthermore, each fixing component 1 has 2-5 slots 2; this range of numbers ensures that the fixing component 1 has sufficient elasticity to adapt to ex vivo tissues of different sizes and shapes, while also preventing the overall strength and stability of the component from being affected by too many slots 2.

[0036] The length of each slot 2 is determined according to the situation; the slots 2 are arranged in parallel. This layout ensures that the stress distribution of the fixed component 1 is uniform when it is under force, avoiding excessive local stress that could damage the component. Moreover, the length of each slot 2 is not fixed, but is flexibly determined according to the actual situation.

[0037] This application also includes an anti-slip component 3, which is disposed on the side wall of the arc end 11 of the fixing component 1;

[0038] The anti-slip component 3 is an anti-slip particle or an anti-slip mat.

[0039] The anti-slip component 3 provided on the side wall of the arc end 11, whether it is anti-slip particles or anti-slip pads, effectively increases the friction between the fixing component 1 and the sample tube 4, preventing it from sliding in the sample tube 4 during the fixing process.

[0040] Furthermore, it also includes a marking area, which is located on the upper and lower surfaces of the fixing component 1; the marking area is embedded with waterproof writing paper.

[0041] The upper and lower surfaces of the fixed component 1 are the easiest parts to observe and touch during the experimental operation. By setting the marking area here, the experimenter can quickly and conveniently view and record the marking information without having to perform complex flipping or adjustment of the fixed component 1.

[0042] Furthermore, the slot 2 is V-shaped, with the opening size at the near-straight end 12 being smaller than that at the other end of the slot 2. The special shape of the V-shaped slot 2 allows the fixing component 1 to achieve a uniform distribution of force when applying clamping force to the detached tissue, while preventing the detached tissue from detaching from the fixing component 1.

[0043] Furthermore, the fixation component 1 is made of elastic polystyrene. The elasticity of the polystyrene gives the fixation component 1 a unique self-adaptive ability. When fixing detached tissue, when the tissue is placed at a specific position on the fixation component 1 (such as at the V-shaped groove 2 mentioned above), the polystyrene will undergo elastic deformation due to the pressure of the tissue.

[0044] In another embodiment, the two fixation components 1 can be used together to fix isolated tissues. The morphologies of isolated tissues encountered in biomedical experiments vary greatly; some isolated tissues may have irregular shapes or unique local structures. A single fixation component 1 may not be able to fully adapt to these complex morphologies, while using two fixation components 1 together allows for flexible adjustment according to the actual shape of the tissue.

[0045] Meanwhile, the specific dimensions of the fixing component 1 are not limited. When it is used in conjunction with the sample tube 4 on the Bruce SkyScan instrument, the dimensions can be selected as needed.

[0046] The fitting of the fixation component 1 and the sample tube 4 in this application can ensure that the ex vivo tissue is stably fixed in the sample tube 4, avoiding artifacts caused by movement during scanning, thereby ensuring the clarity and accuracy of the imaging.

[0047] The present invention has been further described above with reference to the embodiments, but the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. An ex vivo tissue fixation assembly, characterized in that: It includes an integrally formed fixing component (1), one side of which is an arc-shaped end (11), and the other side has a straight end (12) with multiple slots (2). Each slot (2) is set in parallel, with one end of each slot (2) extending toward the arc end (11) and the other end passing through the straight end (12); Each fixing component (1) is sequentially inserted into the sample tube (4).

2. The ex vivo tissue fixation assembly according to claim 1, characterized in that: Each fixing component (1) has 2-5 slots (2); The length of each slot (2) is determined according to the situation.

3. The ex vivo tissue fixation assembly according to claim 1, characterized in that: It also includes an anti-slip component (3), which is located on the side wall of the arc end (11) of the fixing component (1); The anti-slip component (3) is an anti-slip particle or an anti-slip mat.

4. The ex vivo tissue fixation assembly according to claim 1, characterized in that: It also includes a marking area, which is located on the upper and lower surfaces of the fixing component (1); The marking area is embedded with waterproof writing paper.

5. The ex vivo tissue fixation assembly according to claim 1, characterized in that: The slot (2) is V-shaped, and the opening size of the near straight end (12) is smaller than that of the other end of the slot (2).

6. The ex vivo tissue fixation assembly according to claim 1, characterized in that: The fixing component (1) is made of elastic polystyrene.

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