A multifunctional cell harvester

CN224655349UActive Publication Date: 2026-08-21ZHONGKE HUAXIA BIOMEDICAL RES GRP CO LTD
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Patent Information

Application Number
CN202520933989.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-05-13
Publication Date
2026-08-21
Estimated Expiration
2035-05-13

AI Technical Summary

Technical Problem

[0004]本实用新型的目的在于提供一种多功能的细胞采集器,以解决上述背景技术中提出的细胞样本从采集到送检时,样本保存条件不理想,现有的储存方式难以维持稳定低温环境,常规储存容器隔热和蓄冷措施不佳,运输中外界温度波动影响样本保存温度,致使细胞代谢加快、样本质量下降,影响后续检测分析结果的问题

Benefits of technology

[0014]本实用新型通过在样本保护管的外部增加有可拆卸且可重复使用的冷存保护装置,冷存保护装置在未使用时会放置在冷藏箱中进行冷冻,使得装置内部的硅溶胶处于冷冻状态,当细胞采集拭子头采集好样本细胞之后会通过采集杆插入到样本保护管中,此时可直接把冷冻状态的冷存保护装置套接固定在样本保护管的外部,该装置利用内部冷冻的硅溶胶持续为样本保护管内的细胞样本提供低温环境,有效减缓细胞代谢速度,防止细胞活性降低或变质,最大程度保证细胞样本的原始状态和完整性,提升样本质量,为后续精准的细胞检测和分析奠定基础,且其可拆卸、可重复使用的特性,极大地降低了使用成本,并减少资源浪费,而且安装便捷,能在采集样本后迅速为样本提供保护,此外,弹性阻尼橡胶环可紧密绑缚在样本保护管上,进一步增强密封性和稳定性,确保装置的保护效果。

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Abstract

The utility model discloses a multifunctional cell collector, including sample protection pipe and setting operation head at sample protection pipe top, the operation head bottom end center place is fixed with the collection rod, the collection rod perpendicular plug -in at sample protection pipe center place inside, and the length of collection rod is less than the length of sample protection pipe, the collection rod bottom end outside is fixed with cell collection swab head, through adding detachable, reusable cold storage protection device outside sample protection pipe, when not using, the device is frozen in the freezer, and the inside silica sol is in frozen state, after cell collection, collection rod is inserted to sample protection pipe, and the frozen cold storage protection device is sleeved outside sample protection pipe, and low temperature is provided continuously by silica sol, slows down cell metabolism, prevents active reduction or metamorphism, guarantees sample original state and integrity, improves quality, lays the foundation for detection analysis, and its characteristics reduce cost, reduce waste.
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Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, specifically relating to a multifunctional cell collector. Background Technology

[0002] A cell collector is a medical device used to collect human cell samples. The collection head of the cell collector is the part that directly contacts the lesion site and collects cells; it comes in various materials and shapes. For example, the brush head of a cervical cell collector is often made of soft nylon or polyester, which can effectively collect cells from the cervical surface and cervical canal without damaging tissue. The collection tube is used to collect and preserve the collected cell samples. It usually has a sealed cap to prevent sample leakage and contamination. Some collection tubes also contain cell preservation fluid to maintain cell morphology and viability, facilitating subsequent transportation and testing. In the field of cell sample collection and testing, ensuring the quality and viability of cell samples is crucial.

[0003] Currently, the process of cell sample collection and delivery faces the challenge of suboptimal sample preservation conditions. After collection, cell samples need to be stored in a suitable environment to prevent cell deterioration and viability decline. However, existing storage methods often struggle to effectively maintain a stable low-temperature environment. Conventional storage containers lack adequate insulation and cooling measures, and fluctuations in ambient temperature during transportation can easily affect the sample preservation temperature, leading to accelerated cell metabolism, decreased sample quality, and consequently, impacting subsequent testing and analysis results. Utility Model Content

[0004] The purpose of this invention is to provide a multifunctional cell collector to solve the problems mentioned in the background art, such as unsatisfactory sample preservation conditions from collection to delivery, difficulty in maintaining a stable low-temperature environment with existing storage methods, inadequate heat insulation and cold storage measures of conventional storage containers, and the impact of external temperature fluctuations during transportation on sample preservation temperature, which leads to accelerated cell metabolism, decreased sample quality, and affected subsequent detection and analysis results.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a multifunctional cell collector, comprising a sample protection tube and an operating head disposed at the top of the sample protection tube, wherein a collection rod is fixed at the center of the bottom end of the operating head, the collection rod is vertically inserted into the center of the sample protection tube, and the length of the collection rod is less than the length of the sample protection tube, a cell collection swab head is fixed to the outside of the bottom end of the collection rod, and the cell collection swab head does not contact the inner wall of the bottom end of the sample protection tube, and a cold storage protection device is sleeved on the outside of the sample protection tube.

[0006] Preferably, the cold storage protection device includes a thin inner sleeve, a thin outer sleeve, and a sealing connecting ring. The thin inner sleeve is fitted over the outside of the sample protection tube, and the thin outer sleeve is fitted over the outside of the thin inner sleeve. The top ends of the thin inner sleeve and the thin outer sleeve are flush. The thin inner sleeve and the thin outer sleeve are connected by a sealing connecting ring, and the top ends of the thin inner sleeve and the thin outer sleeve are fixed and sealed by the sealing connecting ring.

[0007] Preferably, the outer wall of the thin inner sleeve does not contact the inner wall of the thin outer sleeve, and the gap between the thin inner sleeve and the thin outer sleeve is filled with silica sol. The inner diameter of the thin inner sleeve is larger than the outer diameter of the sample protection tube.

[0008] Preferably, the cold storage protection device further includes an elastic damping rubber ring, which is pasted and fixed to the top of the sealing connecting ring. The inner diameter of the elastic damping rubber ring in the normal state when not under force is smaller than the outer diameter of the sample protection tube. After the elastic damping rubber ring is sleeved on the outside of the sample protection tube, it can be elastically bound to the outer wall of the sample protection tube.

[0009] Preferably, a cell sample label is also affixed to the circular outer wall of the middle section of the sample protection tube. The cell sample label is used to record the type, time, collection site, and size information of the collected cells.

[0010] Preferably, the bottom end of the operating head is also fixed with a sealing plug. The sealing plug is sleeved on the outside of the top end of the collection rod, and the sealing plug can be directly inserted into the top opening of the sample protection tube. The outer corner of the bottom end of the sealing plug is treated with a semi-circular arc surface to facilitate its accurate and quick insertion into the top opening of the sample protection tube.

[0011] Preferably, the outer wall of the operating head is also densely covered with concave strip-shaped anti-slip grooves, the sealing and fixing plug is made of medical-grade soft rubber, and the sealing and fixing plug and the sample protection tube are interference-fitted.

[0012] Preferably, a reinforcing ring is provided on the outer wall of the opening at the top of the sample protection tube. The reinforcing ring can prevent the opening of the sample protection tube from cracking when the sealing plug is inserted into the opening of the sample protection tube.

[0013] Compared with the prior art, this utility model provides a multifunctional cell collector with the following beneficial effects:

[0014] This invention adds a detachable and reusable cryogenic protection device to the outside of the sample protection tube. When not in use, the cryogenic protection device is placed in a refrigerator to freeze, keeping the silica sol inside the device frozen. After the cell collection swab head collects sample cells, it is inserted into the sample protection tube via the collection rod. At this time, the frozen cryogenic protection device can be directly fitted and fixed to the outside of the sample protection tube. This device uses the frozen silica sol inside to continuously provide a low-temperature environment for the cell sample inside the sample protection tube, effectively slowing down the cell metabolism rate, preventing cell activity reduction or deterioration, and maximizing the original state and integrity of the cell sample, thus improving sample quality and laying the foundation for subsequent accurate cell detection and analysis. Its detachable and reusable characteristics greatly reduce the cost of use and reduce resource waste. Moreover, it is easy to install and can quickly provide protection for the sample after collection. In addition, the elastic damping rubber ring can be tightly bound to the sample protection tube to further enhance the sealing and stability, ensuring the protective effect of the device. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the installation state of a multifunctional cell collector and cold storage protection device according to this utility model.

[0016] Figure 2 This is a three-dimensional structural diagram of a multifunctional cell collector and cold storage protection device of this utility model in disassembled state.

[0017] Figure 3 This is a schematic diagram of the disassembled planar structure of a multifunctional cell collector and cold storage protection device according to the present invention.

[0018] Figure 4 This is a cross-sectional perspective view of the cold storage protection device of this utility model.

[0019] In the diagram: 1. Cold storage protection device; 2. Sample protection tube; 3. Operating head; 4. Cell sample label; 5. Reinforcing ring; 6. Sealing plug; 7. Collection rod; 8. Cell collection swab head; 9. Thin inner sleeve; 10. Thin outer sleeve; 11. Sealing connection ring; 12. Elastic damping rubber ring. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] This utility model provides, for example Figure 1-4 The multifunctional cell collector shown includes a sample protection tube 2 and an operating head 3 located at the top of the sample protection tube 2. A collection rod 7 is fixed at the center of the bottom end of the operating head 3, and the collection rod 7 is vertically inserted into the center of the sample protection tube 2. The length of the collection rod 7 is less than the length of the sample protection tube 2. This design ensures that the cell collection swab head 8, after being inserted into the sample protection tube 2, will not touch the inner wall of the bottom end of the sample protection tube 2, avoiding damage to the sample protection tube 2 due to contact or collision, and also preventing contamination of the cell collection swab head 8, ensuring the purity and reliability of the collected sample. The cell collection swab head 8 is fixed to the outside of the bottom end of the collection rod 7, and the cell collection swab head 8 does not contact the inner wall of the bottom end of the sample protection tube 2. The working principle of this multifunctional cell collector is based on the coordinated operation of its components to achieve cell sample collection and... Temporary storage facilitates convenient delivery for testing. During the cell collection stage, the operating head 3 controls the collection rod 7. The cell collection swab head 8, fixed at the bottom of the collection rod 7, accurately collects the required cell samples. The inner concave strip-shaped anti-slip grooves densely distributed on the outer wall of the operating head 3 increase the friction when holding the operating head 3, allowing the operator to control the collection action more stably and accurately during the collection process, ensuring that sufficient and qualified cell samples are collected. A cell sample label 4 is also affixed to the circular outer wall of the middle section of the sample protection tube 2. The cell sample label 4 is used to record the type of cells collected, time, collection site, and size information. This facilitates accurate identification and traceability of the samples later, further demonstrating the versatility and comprehensiveness of the cell collector's functions, and ensuring the smooth progress of the entire process from cell sample collection to delivery for testing.

[0022] like Figure 1 , Figure 2 and Figure 3As shown, a sealing plug 6 is fixed to the bottom of the operating head 3. The sealing plug 6 is sleeved on the outside of the top of the collection rod 7, and can be directly inserted into the top opening of the sample protection tube 2. The outer corner of the bottom of the sealing plug 6 is treated with a semi-circular arc surface to facilitate its accurate and quick insertion into the top opening of the sample protection tube 2. The outer wall of the operating head 3 is also densely covered with concave strip-shaped anti-slip grooves. The sealing plug 6 is made of medical-grade soft rubber, and there is an interference fit between the sealing plug 6 and the sample protection tube 2. The medical-grade soft rubber material is safe and non-toxic and will not contaminate the cell sample, meeting medical use standards. The interference fit forms a tight seal between the sealing plug 6 and the sample protection tube 2, which can effectively prevent external air, moisture and impurities from entering the sample protection tube 2, providing a stable and reliable preservation environment for the stored cell sample, ensuring the quality and activity of the sample. The top opening of the sample protection tube 2... A reinforcing ring 5 is also provided on the outer wall of the opening. The reinforcing ring 5 can prevent the opening of the sample protection tube 2 from cracking when the sealing plug 6 is inserted into the opening. During operation, the curved surface can guide the insertion, reduce the resistance during the insertion process, make the operation smoother, improve work efficiency, and also reduce the possibility of damage to the sample protection tube 2 or the sealing plug 6 due to improper operation. After collection, the cell collection swab head 8 with the sample is vertically inserted into the sample protection tube 2 through the collection rod 7 to achieve temporary storage of sample cells. The reinforcing ring 5 at the top opening of the sample protection tube 2 can prevent the opening of the sample protection tube 2 from cracking when the sealing plug 6 is inserted. The sealing plug 6, made of medical-grade soft rubber and with an interference fit to the sample protection tube 2, can not only tightly seal the sample protection tube 2 to prevent the sample from being contaminated by the outside, but also ensure the stability of the sample during transportation.

[0023] like Figure 1 and Figure 4As shown, a cold storage protection device 1 is fitted onto the outside of the sample protection tube 2. The cold storage protection device 1 includes a thin inner sleeve 9, a thin outer sleeve 10, and a sealing connecting ring 11. The thin inner sleeve 9 is fitted onto the outside of the sample protection tube 2, and the thin outer sleeve 10 is fitted onto the outside of the thin inner sleeve 9. The top ends of the thin inner sleeve 9 and the thin outer sleeve 10 are flush. The thin inner sleeve 9 and the thin outer sleeve 10 are connected by a sealing connecting ring 11, and the top ends of the thin inner sleeve 9 and the thin outer sleeve 10 are fixed and sealed by the sealing connecting ring 11. The outer wall of the thin inner sleeve 9 does not contact the inner wall of the thin outer sleeve 10, and the gap between the thin inner sleeve 9 and the thin outer sleeve 10 is filled with silica sol. The inside of the thin inner sleeve 9... The diameter is larger than the outer diameter of the sample protection tube 2. When not in use, the cold storage protection device 1 is placed in a refrigerator to freeze. At this time, the silica sol filled inside is in a frozen state. Silica sol has good cold storage performance and can store a large amount of cold energy. When the cell collection is completed, after the sample protection tube 2 with the sample is prepared, the frozen cold storage protection device 1 is put on the outside of the sample protection tube 2. Since the inner diameter of the thin inner tube 9 is larger than the outer diameter of the sample protection tube 2, it can be easily put on the sample protection tube 2. The top of the thin inner tube 9 and the thin outer tube 10 are fixed and sealed by the sealing connection ring 11 to ensure the airtightness of the entire device and reduce the intrusion of external heat.

[0024] like Figure 1 and Figure 4 As shown, the cold storage protection device 1 also includes an elastic damping rubber ring 12. The elastic damping rubber ring 12 is glued and fixed to the top of the sealing connecting ring 11. In the normal state when the elastic damping rubber ring 12 is not under stress, its inner diameter is smaller than the outer diameter of the sample protection tube 2. After the elastic damping rubber ring 12 is fitted onto the outside of the sample protection tube 2, it can be elastically bound to the outer wall of the sample protection tube 2. The outer wall of the thin inner sleeve 9 does not contact the inner wall of the thin outer sleeve 10. The cold energy stored in the silica sol filling the gap during freezing will be slowly released to the sample protection tube 2 surrounded by the thin inner sleeve 9, thereby creating a low-temperature environment for the cell sample inside the sample protection tube 2. This low-temperature environment can significantly slow down the metabolic rate of cells and reduce... The reduction in cell viability effectively prevents cell deterioration and maintains the original state and integrity of the cell sample to the greatest extent. The elastic damping rubber ring 12, which is attached to the top of the sealing connection ring 11, has an inner diameter smaller than the outer diameter of the sample protection tube 2 when it is not under stress. When it is fitted onto the outside of the sample protection tube 2, it can be tightly bound to the outer wall of the sample protection tube 2 by its own elasticity. This not only further enhances the connection stability between the cold storage protection device 1 and the sample protection tube 2 and prevents the device from shifting during handling or transportation, but also plays a certain role in sealing, reducing the channels for heat exchange, better maintaining the internal low temperature environment, and ensuring that the cell sample is always in a good preservation state during the testing process.

[0025] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A multifunctional cell collector, comprising a sample protection tube (2) and an operating head (3) disposed at the top of the sample protection tube (2), wherein a collection rod (7) is fixed at the center of the bottom end of the operating head (3), the collection rod (7) is vertically inserted into the center of the sample protection tube (2), and the length of the collection rod (7) is less than the length of the sample protection tube (2), characterized in that: A cell collection swab head (8) is fixed to the outside of the bottom end of the collection rod (7), and the cell collection swab head (8) does not contact the inner wall of the bottom end of the sample protection tube (2). A cold storage protection device (1) is sleeved on the outside of the sample protection tube (2). The cold storage protection device (1) includes a thin inner sleeve (9), a thin outer sleeve (10), and a sealing connecting ring (11). The thin inner sleeve (9) is sleeved on the outside of the sample protection tube (2). The thin outer sleeve (10) is sleeved on the outside of the thin inner sleeve (9). The top ends of the thin inner sleeve (9) and the thin outer sleeve (10) are flush. The thin inner sleeve (9) and the thin outer sleeve (10) are connected by a sealing connecting ring (11), and the top ends of the thin inner sleeve (9) and the thin outer sleeve (10) are fixed and sealed by the sealing connecting ring (11).

2. The multifunctional cell collector according to claim 1, characterized in that: The outer wall of the thin inner sleeve (9) does not contact the inner wall of the thin outer sleeve (10), and the gap between the thin inner sleeve (9) and the thin outer sleeve (10) is filled with silica sol. The inner diameter of the thin inner sleeve (9) is larger than the outer diameter of the sample protection tube (2).

3. A multifunctional cell collector according to claim 2, characterized in that: The cold storage protection device (1) also includes an elastic damping rubber ring (12). The elastic damping rubber ring (12) is pasted and fixed to the top of the sealing connecting ring (11). The inner diameter of the elastic damping rubber ring (12) in the normal state when it is not under force is smaller than the outer diameter of the sample protection tube (2). After the elastic damping rubber ring (12) is sleeved on the outside of the sample protection tube (2), it can be bound to the outer wall of the sample protection tube (2) by its own elasticity.

4. A multifunctional cell collector according to claim 1, characterized in that: The middle section of the sample protection tube (2) is also covered with a cell sample label (4), which is used to record the type, time, collection site and size of the collected cells.

5. A multifunctional cell collector according to claim 1, characterized in that: The bottom end of the operating head (3) is also fixed with a sealing plug (6). The sealing plug (6) is sleeved on the outside of the top end of the collection rod (7), and the sealing plug (6) can be directly inserted into the top opening of the sample protection tube (2). The outer corner of the bottom end of the sealing plug (6) is treated with a semi-circular arc surface to facilitate its accurate and quick insertion into the top opening of the sample protection tube (2).

6. A multifunctional cell collector according to claim 5, characterized in that: The outer wall of the operating head (3) is also densely covered with concave strip-shaped anti-slip grooves. The sealing and fixing plug (6) is made of medical grade soft rubber, and the sealing and fixing plug (6) and the sample protection tube (2) are interference fit.

7. A multifunctional cell collector according to claim 6, characterized in that: A reinforcing ring (5) is also provided on the outer wall of the top opening of the sample protection tube (2). The reinforcing ring (5) can prevent the sample protection tube (2) from cracking when the sealing plug (6) is inserted into the opening of the sample protection tube (2).