Press-fit structure of a multi-layer cell culture plate

Abstract

The utility model relates to cell culture plate press -mounting technical field, and disclose a kind of press -mounting structure of multilayer cell culture plate, including base, the top end diagonal side of base is evenly provided with limit sliding slot, the top end middle part of base is fixedly connected with support column, the top end of support column is fixedly connected with workstation, the top of workstation is movably provided with cell culture plate, the top end middle part of base is fixedly connected with support frame by bolt;The press -mounting structure of multilayer cell culture plate further includes: limit component, two double-end sleeve ring rods relatively move, and then drive two moving bases relatively move, the half profiled slider of the bottom end of two moving bases slides in the outer wall of profiled slide rod, it is favorable to the moving stable support of moving base, and then drive two clamping plates relatively move, under the protection of antiskid rubber pad, the two sides of cell culture plate are limited and fixed, ensure that deviation does not occur when press -mounting to cell culture plate, influence press -mounting precision.

Description

Technical Field

[0001] This utility model relates to the field of cell culture plate pressing technology, and more specifically to a pressing structure for a multilayer cell culture plate. Background Technology

[0002] In high-throughput experiments in cell biology, immunology, and other fields, multilayer cell culture plates are the core tool for achieving parallel culture of multiple samples, and are widely used in experiments such as cell proliferation, drug screening, and virus detection. These culture plates typically consist of a plate body and a cover plate. Some multilayer structures require press fitting to ensure the interlayer adhesion. If the press fitting is not tight, it can easily lead to leakage of culture medium, cross-contamination, or abnormal gas exchange, directly affecting the accuracy of experimental results. If the press fitting force is too great, it may damage the microporous structure of the culture plate and disrupt the cell growth environment.

[0003] According to the search, the commonly used method is manual pressing with no limit. The experimenter directly presses the cover of the culture plate with his hand or a simple pressure plate without a special limit structure. This method is easy to operate, but the pressing force is entirely controlled by experience, which can easily lead to local loose pressing or excessive pressing. In addition, multi-layer culture plates are prone to displacement due to uneven force applied by the hand, resulting in poor pressing consistency.

[0004] The shortcomings of existing technologies are as follows: When pressing existing multilayer cell culture plates, manual pressing has no compatibility, the snap-on pressing base has a narrow compatibility range, and the manual adjustment screw device requires frequent adjustment of the limiting structure. None of these technologies can quickly adapt to multilayer culture plates of different specifications. In addition, the plates are prone to displacement during the pressing process, resulting in uneven adhesion between layers and affecting the reproducibility of experiments.

[0005] Therefore, there is a need to provide a press-fit structure for multilayer cell culture plates to solve the problems mentioned above. Utility Model Content

[0006] In order to overcome the above-mentioned defects of the prior art, the present invention provides a press-fit structure for a multilayer cell culture plate to solve the problems existing in the background art.

[0007] This utility model provides the following technical solution: a press-fit structure for a multi-layer cell culture plate, including a base, with limit grooves provided on the diagonal sides of the top of the base, a support column fixedly connected to the middle of the top of the base, a worktable fixedly connected to the top of the support column, a cell culture plate movably mounted on the top of the worktable, and a support frame fixedly connected to the middle of the top of the base by bolts. The press-fit structure of multilayer cell culture plates also includes: A limiting component is disposed on the top of the base and is used to limit and fix the two sides of the cell culture plate. A pressing assembly is disposed in the middle of the support frame and at the top of the cell culture plate, and is used to press the cell culture plate. Preferably, the limiting component includes: Two I-shaped sliding rods are provided, with their bottom ends fixedly connected to the top of the base at diagonal angles. A semi-I-shaped slider is slidably fitted onto the outer wall of each of the two I-shaped sliding rods. A movable seat is fixedly fitted onto the outer wall of each of the two semi-I-shaped sliders. A clamping plate is fixedly connected to the top of each of the two movable seats by bolts. Anti-slip rubber pads are fixedly connected to opposite sides of each of the two clamping plates, and the opposite sides of the two anti-slip rubber pads movably abut against the outer wall of the cell culture plate. A guiding mechanism is provided between two movable seats to drive the two movable seats to move relative to each other.

[0008] Preferably, the guide mechanism includes a movable seat, the bottom end of which is fixedly connected to the top of the base, and a cylinder is movably sleeved in the middle of the movable seat. The left end of the cylinder is fixedly connected to a movable seat on the left side.

[0009] Preferably, each of the two movable seats has a fixed post fixedly connected to one of its top ends that are far apart from each other. The outer walls of the two fixed posts are movably fitted with double-headed collar rods. The opposite ends of the two double-headed collar rods are movably fitted with rotating plates through the fixed posts. The middle part of the rotating plates is movably fitted with the outer wall of the support post.

[0010] Preferably, the bottom ends of the two movable seats are fixedly connected to the opposite sides of each other, and the outer walls of the two limiting sliders are slidably connected in the two limiting grooves.

[0011] Preferably, the press-fit assembly includes a threaded rod, the outer wall of which is threadedly connected to the middle of the support frame, a pad is fixedly connected to the bottom end of the threaded rod, a press-fit plate is fixedly connected to the bottom end of the pad, and a rotating handle is fixedly connected to the top end of the threaded rod.

[0012] The technical effects and advantages of this utility model are as follows: 1. This utility model, by providing a limiting component, places the cell culture plate on the worktable at the top of the support column. With the support of the movable seat, the cylinder is activated, driving the left movable seat to move. Under the connection of the fixed column, the double-headed collar rod moves, thereby pushing the rotating plate to rotate. With the connection of the two fixed columns at the top of the rotating plate, the two double-headed collar rods move relative to each other, thereby driving the two movable seats to move relative to each other. The semi-I-shaped sliders at the bottom of the two movable seats slide on the outer wall of the I-shaped slider, which helps to stabilize the movement of the movable seats. This, in turn, drives the two clamping plates to move relative to each other. With the protection of the anti-slip rubber pad, the two sides of the cell culture plate are limited and fixed, ensuring that the cell culture plate will not shift during pressing, thus affecting the pressing accuracy.

[0013] 2. This utility model has a pressing assembly. After the limiting assembly limits and fixes the cell culture plate, rotating the handle drives the threaded rod to move down at the support frame, which in turn drives the pad and pressing plate to move down to apply pressure to the top of the cell culture plate, thus facilitating the pressing of multilayer cell culture plates. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0015] Figure 2 This is an exploded view of the overall structure of this utility model.

[0016] Figure 3 This is a schematic diagram of the limiting component of this utility model.

[0017] Figure 4 This is a schematic diagram of the press-fitting component of this utility model.

[0018] The attached diagram is labeled as follows: 1. Support frame; 2. Pressing assembly; 201. Rotating handle; 202. Threaded rod; 203. Pad; 204. Pressing plate; 3. Clamping plate; 301. Anti-slip rubber pad; 4. Cell culture plate; 5. Base; 501. Limiting groove; 6. Limiting assembly; 601. I-shaped slide bar; 602. Moving seat; 603. Semi-I-shaped slider; 604. Double-headed collar rod; 605. Cylinder; 606. Movable seat; 607. Limiting slider; 608. Rotating plate; 7. Support column; 8. Worktable. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0020] like Figure 1-4 As shown, this utility model has the following two specific embodiments.

[0021] Example 1 This utility model is a press-fit structure for a multi-layer cell culture plate, including a base 5. Limiting grooves 501 are provided on the diagonal sides of the top of the base 5. A support column 7 is fixedly connected to the middle of the top of the base 5. A worktable 8 is fixedly connected to the top of the support column 7. A cell culture plate 4 is movably arranged on the top of the worktable 8. A support frame 1 is fixedly connected to the middle of the top of the base 5 by bolts. The press-fit structure of multilayer cell culture plates also includes: Limiting component 6 is disposed on the top of the base 5 and is used to limit and fix the two sides of the cell culture plate 4. Pressing assembly 2 is located in the middle of the support frame 1 and at the top of the cell culture plate 4, and is used to press the cell culture plate 4.

[0022] Limiting component 6 includes: Two I-shaped slide rods 601 are fixedly connected at their bottom ends to the top diagonally opposite ends of the base 5. Half-I-shaped sliders 603 are slidably sleeved on the outer walls of the two I-shaped slide rods 601. Movable seats 602 are fixedly sleeved on the outer walls of the two half-I-shaped sliders 603. Clamping plates 3 are fixedly connected to the top ends of the two movable seats 602 by bolts. Anti-slip rubber pads 301 are fixedly connected to the opposite sides of the two clamping plates 3. The opposite sides of the two anti-slip rubber pads 301 are in movable contact with the outer wall of the cell culture plate 4. A guiding mechanism is provided between two movable seats 602 to drive the two movable seats 602 to move relative to each other.

[0023] The guiding mechanism includes a movable seat 606, the bottom of which is fixedly connected to the top of the base 5. A cylinder 605 is movably sleeved in the middle of the movable seat 606, and the left end of the cylinder 605 is fixedly connected to the movable seat 602 on the left side.

[0024] The top ends of the two movable seats 602 that are far apart from each other are fixedly connected to fixed columns. The outer walls of the two fixed columns are movably sleeved with double-headed collar rods 604. The opposite ends of the two double-headed collar rods 604 are movably sleeved with rotating plates 608 through the fixed columns. The middle part of the rotating plates 608 is movably sleeved with the outer wall of the support column 7.

[0025] Limiting sliders 607 are fixedly connected to the bottom ends of the two movable seats 602 on opposite sides, and the outer walls of the two limiting sliders 607 are slidably connected to the two limiting grooves 501.

[0026] In this embodiment, as Figure 1-3 As shown, when cylinder 605 is turned on, the left movable seat 602 moves, which in turn moves the double-headed collar rod 604 under the connection of the fixed column, thereby pushing the rotating plate 608 to rotate. Under the connection of the two fixed columns at the top of the rotating plate 608, the two double-headed collar rods 604 move relative to each other, which in turn moves the two movable seats 602 relative to each other. The semi-I-shaped sliders 603 at the bottom of the two movable seats 602 slide on the outer wall of the I-shaped slider 601, providing stable support for the movement of the movable seats 602, which in turn moves the two clamping plates 3 relative to each other. Under the protection of the anti-slip rubber pad 301, the two sides of the cell culture plate 4 are limited and fixed.

[0027] Example 2 The difference from Embodiment 1 is that this embodiment discloses that the press-fit assembly 2 includes a threaded rod 202, the outer wall of the threaded rod 202 is threadedly connected to the middle part of the support frame 1, a pad 203 is fixedly connected to the bottom end of the threaded rod 202, a press-fit plate 204 is fixedly connected to the bottom end of the pad 203, and a rotating handle 201 is fixedly connected to the top end of the threaded rod 202.

[0028] In this embodiment, as Figure 1-2 and Figure 4 As shown, after the limiting component 6 limits and fixes the cell culture plate 4, the rotating handle 201 is rotated, which drives the threaded rod 202 to move down at the support frame 1, thereby driving the pad 203 and the pressing plate 204 to move down and apply pressure to the top of the cell culture plate 4.

[0029] The working principle of this utility model is as follows: The cell culture plate 4 is placed on the workbench 8 at the top of the support column 7. With the support of the movable seat 606, the cylinder 605 is activated, which drives the left movable seat 602 to move. Under the connection of the fixed column, the double-headed collar rod 604 moves, which in turn pushes the rotating plate 608 to rotate. Under the connection of the two fixed columns at the top of the rotating plate 608, the two double-headed collar rods 604 move relative to each other, which in turn drives the two movable seats 602 to move relative to each other. The semi-I-shaped sliders 603 at the bottom of the two movable seats 602 move accordingly on the outer wall of the I-shaped slider 601. The sliding mechanism provides stable support for the movement of the movable seat 602, thereby driving the two clamping plates 3 to move relative to each other. Under the protection of the anti-slip rubber pad 301, the two sides of the cell culture plate 4 are limited and fixed to ensure that there is no deviation when pressing the cell culture plate 4. After the limiting component 6 limits and fixes the cell culture plate 4, the rotating handle 201 is rotated, which drives the threaded rod 202 to move down at the support frame 1, thereby driving the pad 203 and the pressing plate 204 to move down to apply pressure to the top of the cell culture plate 4, thereby performing the pressing work on the multilayer cell culture plate 4.

[0030] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "linkage" should be interpreted broadly, and can be mechanical or electrical connections, or internal connections between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may change. Secondly: The accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other. Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A press-fit structure for a multilayer cell culture plate, comprising a base (5), characterized in that: Limiting grooves (501) are provided on the diagonal sides of the top of the base (5). A support column (7) is fixedly connected to the middle of the top of the base (5). A workbench (8) is fixedly connected to the top of the support column (7). A cell culture plate (4) is movably arranged on the top of the workbench (8). A support frame (1) is fixedly connected to the middle of the top of the base (5) by bolts. The press-fit structure of multilayer cell culture plates also includes: Limiting component (6), which is disposed on the top of the base (5) and is used to limit and fix the two sides of the cell culture plate (4); Pressing assembly (2), which is located in the middle of the support frame (1) and at the top of the cell culture plate (4), is used to press the cell culture plate (4).

2. The press-fitting structure of a multilayer cell culture plate according to claim 1, characterized in that: The limiting component (6) includes: Two I-shaped slide rods (601) are fixedly connected at the bottom of the two I-shaped slide rods (601) to the top of the base (5) at an angle. The outer walls of the two I-shaped slide rods (601) are slidably fitted with half I-shaped sliders (603). The outer walls of the two half I-shaped sliders (603) are fixedly fitted with movable seats (602). The top of the two movable seats (602) are fixedly connected with clamping plates (3) by bolts. The opposite sides of the two clamping plates (3) are fixedly connected with anti-slip rubber pads (301). The opposite sides of the two anti-slip rubber pads (301) are in movable contact with the outer wall of the cell culture plate (4). A guiding mechanism is provided between two movable seats (602) for driving the two movable seats (602) to move relative to each other.

3. The press-fitting structure of a multilayer cell culture plate according to claim 2, characterized in that: The guiding mechanism includes a movable seat (606), the bottom end of which is fixedly connected to the top of the base (5), and a cylinder (605) is movably sleeved in the middle of the movable seat (606). The left end of the cylinder (605) is fixedly connected to the movable seat (602) on the left side.

4. The press-fitting structure of a multilayer cell culture plate according to claim 2, characterized in that: The top ends of the two movable seats (602) that are far apart from each other are fixedly connected to a fixed column. The outer walls of the two fixed columns are movably sleeved with double-headed collar rods (604). The opposite ends of the two double-headed collar rods (604) are movably sleeved with rotating plates (608) through the fixed columns. The middle part of the rotating plates (608) is movably sleeved with the outer wall of the support column (7).

5. The press-fitting structure of a multilayer cell culture plate according to claim 2, characterized in that: The bottom ends of the two movable seats (602) are fixedly connected to the opposite sides of each other, and the outer walls of the two limiting sliders (607) are slidably connected in the two limiting grooves (501).

6. The press-fitting structure of a multilayer cell culture plate according to claim 1, characterized in that: The press-fit assembly (2) includes a threaded rod (202), the outer wall of which is threadedly connected to the middle part of the support frame (1), a pad (203) is fixedly connected to the bottom end of the threaded rod (202), a press-fit plate (204) is fixedly connected to the bottom end of the pad (203), and a rotating handle (201) is fixedly connected to the top end of the threaded rod (202).

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