Liquid injection mechanism of drop dyeing HE dyeing machine

Abstract

The utility model discloses a kind of liquid injection mechanism of drop dyeing HE dyeing machine, including liquid injection mounting frame, liquid injection transverse shift module is equipped on the liquid injection mounting frame, lifting mounting plate is equipped on the output end of liquid injection transverse shift module, liquid injection lifting module and needle tube cleaning component are equipped on the lifting mounting plate, liquid injection needle is equipped on the output end of liquid injection lifting module, and one end of liquid injection needle is connected with liquid injection pump;Liquid injection transverse shift module is used to drive the liquid injection needle moves along the length direction of bunker, liquid injection lifting module can drive the liquid injection needle to extend into the material groove of bunker, the liquid injection needle is used to inject liquid medicine into material groove, liquid injection lifting module can also drive the liquid injection needle and the needle tube cleaning component are connected, and the needle tube cleaning component is used to clean liquid injection needle.The utility model can realize accurate positioning and automatic liquid injection of liquid injection needle, significantly improve liquid injection efficiency, reduce manual intervention, and be applicable to continuous batch operation.

Description

Technical Field

[0001] This utility model relates to the field of HE staining machine technology, specifically to a liquid injection mechanism for a drop HE staining machine. Background Technology

[0002] Staining is of great significance in the diagnosis of pathological tissue morphology, scientific experimental research, and teaching. Without staining tissue sections, the internal structure of the tissue cannot be seen, and the cell nuclei cannot be identified. Therefore, researchers cannot provide a basis for judgment to determine whether the tissue is abnormal.

[0003] HE staining uses hematoxylin and eosin to stain the nucleus and cytoplasm, respectively, to distinguish the morphology of normal cells. In practical applications, it can identify abnormal pathological changes such as tissue cell necrosis, edema, degeneration, and inflammatory cell infiltration.

[0004] Currently, most tissue section staining processes are still manual, requiring operators to manually draw the staining solution and inject it into the hopper containing the tissue sections, ensuring thorough contact between the solution and the sections. This method is highly inefficient. Replacing manual labor with automated equipment has become an inevitable trend in industry transformation and upgrading. Therefore, there is an urgent need for equipment capable of automatically staining tissue sections, which necessitates the design of a mechanism that automatically injects the staining solution into the hopper. Utility Model Content

[0005] To address some or all of the problems existing in the prior art, this utility model provides a liquid injection mechanism for a drop staining HE staining machine. The drop staining HE staining machine includes a machine base with a material hopper channel on the machine base for conveying a material hopper containing tissue sections. Multiple material slots for placing tissue sections are evenly distributed on the upper surface of the material hopper. The liquid injection mechanism includes a liquid injection mounting frame connected to the machine base. A liquid injection transverse movement module is mounted on the liquid injection mounting frame, and a lifting mounting plate is mounted on the output end of the liquid injection transverse movement module. The lifting mounting plate is equipped with an injection lifting module and a needle cleaning assembly. The output end of the injection lifting module is equipped with an injection needle, one end of which is connected to an injection pump. The injection lateral movement module is used to drive the injection needle to move along the length of the hopper. The injection lifting module can drive the injection needle to extend into the material tank. The injection needle is used to inject liquid medicine into the material tank. The injection lifting module can also drive the injection needle to connect with the needle cleaning assembly, which is used to clean the injection needle.

[0006] As a further improvement of this utility model, the liquid injection transverse movement module includes a liquid injection transverse movement fixing seat, which is connected to the liquid injection mounting frame. The liquid injection transverse movement fixing seat is provided with a lead screw assembly and a liquid injection transverse movement motor. The output end of the liquid injection transverse movement motor is connected to the lead screw assembly. A liquid injection transverse movement slider is slidably provided on the liquid injection transverse movement fixing seat. The liquid injection transverse movement slider is connected to the lead screw assembly. The lifting mounting plate is connected to the liquid injection transverse movement slider.

[0007] As a further improvement of this utility model, the liquid injection lifting module includes a liquid injection lifting motor, which is connected to the lifting mounting plate. The lifting mounting plate is provided with a liquid injection lifting driven wheel, and the output end of the liquid injection lifting motor is provided with a liquid injection lifting driving wheel. A liquid injection lifting transmission belt is sleeved on the liquid injection lifting driving wheel and the liquid injection lifting driven wheel. A liquid injection lifting slider is provided on the liquid injection lifting transmission belt, and the liquid injection needle is connected to the liquid injection lifting slider.

[0008] As a further improvement of this utility model, the injection mounting bracket is provided with an injection lifting guide rail, and the injection lifting slider is slidably engaged with the injection lifting guide rail.

[0009] As a further improvement of this utility model, the lifting mounting plate is provided with a positioning sensor, and the liquid injection lifting slider is provided with a detection lever, which can be connected to the positioning sensor.

[0010] As a further improvement of this utility model, the needle cleaning assembly includes a cleaning mounting frame connected to the lifting mounting plate. The cleaning mounting frame is provided with a cleaning tank, and the cleaning tank has a needle hole penetrating through the upper and lower end faces of the cleaning tank. The injection needle can pass through the needle hole and is clearance-fitted with the needle hole. The side wall of the cleaning tank is provided with a water inlet connector and a water outlet connector, which are respectively connected to the needle hole. The water inlet connector is connected to the cleaning liquid, and the water outlet connector is connected to the negative pressure suction device.

[0011] As a further improvement of this utility model, the cleaning tank is made of a flexible material.

[0012] As a further improvement of this utility model, the lower end face of the injection needle is a sealed structure, and the liquid outlet of the injection needle is located on the side wall of the injection needle.

[0013] Compared with the prior art, the beneficial effects of this utility model are: 1. This utility model achieves precise positioning of the injection needle and automatic injection by combining the injection horizontal movement module and the injection lifting module, which significantly improves injection efficiency, reduces manual intervention, and is suitable for continuous batch operations.

[0014] 2. The movement trajectory and injection position of the injection needle are controlled by mechanical drive to ensure that the amount of drug solution injected into each tank is consistent, thereby improving the repeatability of dyeing quality.

[0015] 3. By setting up a needle cleaning component, this utility model can automatically clean the injection needle after the injection is completed, preventing contamination caused by residues between different solutions and ensuring the accuracy of the staining results.

[0016] 4. The structure of sealing the lower end of the injection needle and discharging liquid from the side wall effectively prevents the liquid from dripping when the needle is lifted, avoiding contamination of adjacent material tanks or equipment and improving the cleanliness of the operation. Attached Figure Description

[0017] To more clearly illustrate the solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the structure of the silo in an embodiment of this utility model; Figure 2 This is a schematic diagram of the overall structure of an embodiment of this utility model; Figure 3 This is a schematic diagram of the structure of the liquid injection transverse movement module in an embodiment of this utility model; Figure 4 This is a schematic diagram of the structure of the liquid injection lifting module in an embodiment of this utility model; Figure 5 This is a schematic diagram of the liquid injection lifting module from another perspective in an embodiment of this utility model; Figure 6 This is a schematic diagram of the needle cleaning assembly in an embodiment of the present invention. Detailed Implementation

[0019] Unless otherwise defined, all technical and scientific terms used in this invention have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains; the terminology used in the specification is for the purpose of describing particular embodiments only and is not intended to limit the invention; the terms "comprising" and "having," and any variations thereof, in the specification, claims, and accompanying drawings of this invention are intended to cover non-exclusive inclusion. The terms "first," "second," etc., in the specification, claims, or accompanying drawings of this invention are used to distinguish different objects, not to describe a particular order.

[0020] In this invention, the reference to "embodiment" means that a specific feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this invention. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor is it a mutually exclusive, independent, or alternative embodiment to other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described in this invention can be combined with other embodiments.

[0021] To enable those skilled in the art to better understand the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings.

[0022] like Figure 1-6 As shown, a liquid injection mechanism for a drop staining HE staining machine is installed on the machine. The drop staining HE staining machine includes a machine base 100, on which a material hopper channel 200 is provided for conveying a material hopper 300 containing tissue sections. Multiple material troughs 400 are evenly distributed on the upper surface of the material hopper 300, and the material troughs 400 are used to hold glass slides 500 containing tissue sections. The function of the liquid injection mechanism of the drop staining HE staining machine is to inject the solution into the material troughs 400, so that the solution fully contacts the assembled sections in the material hopper 300, thereby achieving the purpose of staining the tissue sections.

[0023] The injection mechanism includes an injection mounting frame 1, which is fixedly connected to the machine base 100. An injection transverse movement module 2 is mounted on the injection mounting frame 1. A lifting mounting plate 3 is mounted on the output end of the injection transverse movement module 2. An injection lifting module 4 and a needle cleaning assembly 5 are mounted on the lifting mounting plate 3. An injection needle 6 is mounted on the output end of the injection lifting module 4, and one end of the injection needle 6 is externally connected to an injection pump. The injection transverse movement module 2 drives the injection needle 6 to move along the length of the material bin, allowing the injection needle 6 to align with each material tank 400 within the material bin 300. The injection lifting module 4 drives the injection needle 6 to extend into or out of the material tank 400, facilitating the staining of tissue sections in each material tank. The injection needle 6 injects the drug solution into the material tank via the external injection pump, allowing the drug solution to stain the tissue sections in the material bin. The injection lifting module 4 can also drive the injection needle 6 to connect with the needle cleaning assembly 5. The needle cleaning assembly 5 is used to clean the injection needle 6. By cleaning the injection needle 6, different medications can be prevented from affecting each other, so that the injection mechanism can be used for the injection of different medications, thus improving the versatility of the equipment.

[0024] Specifically, such as Figure 3As shown, the liquid injection transverse movement module 2 includes a liquid injection transverse movement fixing base 21, which is connected to the liquid injection mounting frame 1. The liquid injection transverse movement fixing base 21 is equipped with a lead screw assembly (not shown in the figure) and a liquid injection transverse movement motor 22. The output end of the liquid injection transverse movement motor 22 is connected to the lead screw assembly. A liquid injection transverse movement slider 23 is slidably mounted on the liquid injection transverse movement fixing base 21 and is connected to the lead screw assembly. During operation, the liquid injection transverse movement motor 22 drives the lead screw assembly to rotate, thereby causing the liquid injection transverse movement slider 23 to slide laterally on the liquid injection transverse movement fixing base 21. The liquid injection transverse movement slider 23 drives the lifting mounting plate 3, the liquid injection lifting module 4, and the liquid injection needle 6 to move synchronously, thereby moving the liquid injection needle 6 to directly above each material trough in the hopper.

[0025] like Figure 4-5 As shown, the liquid injection lifting module 4 includes a liquid injection lifting motor 41, which is fixedly connected to the lifting mounting plate 3. The lifting mounting plate 3 has a liquid injection lifting driven wheel 42, and the output end of the liquid injection lifting motor 41 has a liquid injection lifting drive wheel 43. A liquid injection lifting transmission belt 44 is fitted onto the liquid injection lifting drive wheel 43 and the liquid injection lifting driven wheel 42. A liquid injection lifting slider 45 is mounted on the liquid injection lifting transmission belt 44, and the liquid injection needle 6 is connected to the liquid injection lifting slider 45. During operation, the liquid injection lifting motor 41 drives the liquid injection lifting drive wheel 43 to rotate, which in turn drives the liquid injection lifting transmission belt 44 to move. The liquid injection lifting transmission belt 44 then drives the liquid injection lifting slider 45 and the liquid injection needle 6 to move synchronously, causing the liquid injection needle 6 to extend into or out of the material trough in the hopper.

[0026] To limit and guide the lifting movement of the injection needle 6, an injection lifting guide rail 46 is provided on the lifting mounting plate 3, and the injection lifting slider 45 is slidably engaged with the injection lifting guide rail 46. When the injection lifting motor 41 is working, it drives the injection lifting slider 45 to move; the injection lifting slider 45 is constrained by the injection lifting guide rail 46 and can only slide along the direction of the injection lifting guide rail 46, thereby driving the injection needle 6 to be accurately inserted into the material tank to complete the injection.

[0027] To improve control accuracy, a positioning sensor 47 is installed on the lifting mounting plate 3, and a detection lever 48 is installed on the liquid injection lifting slider 45. The detection lever 48 can connect with the positioning sensor 47. Normally, the detection lever 48 and the positioning sensor 47 are separate. When liquid injection is needed, the liquid injection lifting motor 41 drives the liquid injection lifting slider 45 to descend, causing the injection needle 6 to descend synchronously. As the liquid injection lifting slider 45 descends, the detection lever 48 on the liquid injection lifting slider 45 connects with the positioning sensor 47. At this time, the injection needle 6 is also inserted into the material trough of the hopper. The positioning sensor 47 sends a signal to the controller of the HE dyeing machine, which immediately stops the liquid injection lifting motor 41. Through the cooperation of the detection lever 48 and the positioning sensor 47, the injection needle 6 can be accurately inserted into the material trough, avoiding the problem of inserting too much and breaking the injection needle 6 or piercing the hopper, and also avoiding inaccurate liquid injection due to incomplete insertion.

[0028] To facilitate cleaning of the injection needle 6, in this embodiment, the lower end face of the injection needle 6 is a sealed structure, and the outlet hole of the injection needle 6 is located on the side wall of the injection needle 6. Placing the outlet hole on the side wall of the injection needle 6 prevents the liquid from dripping when the injection needle 6 is raised, avoiding contamination of adjacent material tanks or equipment and improving operational cleanliness. Furthermore, during cleaning, cleaning fluid can be injected into the interior of the injection needle 6 through the outlet hole, thereby cleaning the interior of the injection needle 6.

[0029] Specifically, such as Figure 6 As shown, the syringe cleaning assembly 5 includes a cleaning mounting frame 51, which is fixedly connected to the lifting mounting plate 3. A cleaning tank 52 is mounted on the cleaning mounting frame 51, and the cleaning tank 52 is made of a flexible material (such as silicone). The cleaning tank 52 has a needle hole 53 at its center, penetrating both the upper and lower end faces. An injection needle 6 can pass through the needle hole 53 and is fitted with it with a clearance. During injection, the injection needle 6 passes through the needle hole 53 and extends into the material trough inside the hopper. The side wall of the cleaning tank 52 is provided with a water inlet connector 54 and a water outlet connector 55, both of which are connected to the needle hole 53. The water inlet connector 54 is connected to the cleaning fluid, and the water outlet connector 55 is connected to a negative pressure suction device.

[0030] When cleaning is required, the liquid injection horizontal movement module 2 and the liquid injection lifting module 4 work together to insert the liquid injection needle 6 into the needle hole 53 of the cleaning tank 52. Cleaning fluid is injected into the cleaning tank 52 through the water inlet connector 54. The cleaning fluid flows over the outer wall of the liquid injection needle 6, cleaning its outer wall. Simultaneously, because the outlet hole of the liquid injection needle 6 is on the side wall, some cleaning fluid flows into the interior of the liquid injection needle 6 through the outlet hole, cleaning its interior. At the same time, the water outlet connector 55 generates negative pressure suction through an external negative pressure suction device, which can suck away the waste liquid generated during cleaning in the cleaning tank 52, preventing cleaning fluid overflow.

[0031] Work process: During operation, the material hopper 300 is conveyed to the injection station along the material hopper flow channel 200. The injection transverse motor 22 drives the injection transverse slider 23 to move via a lead screw assembly, aligning the injection needle 6 with one of the material troughs in the hopper. The injection lifting motor 41 drives the injection lifting slider 45 downward via a transmission belt, causing the injection needle 6 to insert into the material trough. The injection pump starts, and the liquid is injected into the material trough from the outlet hole on the side wall of the injection needle 6; after injection, the injection lifting module 4 lifts the injection needle 6. The above process is repeated until all the material troughs containing tissue sections in the hopper have been injected; then the liquid will fully contact the tissue sections in the material troughs to achieve the purpose of staining the tissue sections.

[0032] The above-described specific embodiments are preferred embodiments of this utility model, and are not intended to limit the specific scope of this utility model. The scope of this utility model includes but is not limited to the specific embodiments described above. All equivalent changes made in accordance with this utility model are within the protection scope of this utility model.

Claims

1. A liquid injection mechanism for a hematoxylin and eosin (HE) staining machine, the HE staining machine comprising a machine base, a material hopper channel provided on the machine base for conveying a material hopper containing tissue sections, and multiple material slots for placing tissue sections evenly distributed on the upper end surface of the material hopper, characterized in that: The injection mechanism includes an injection mounting frame connected to the machine base. An injection transverse movement module is provided on the injection mounting frame. A lifting mounting plate is provided on the output end of the injection transverse movement module. An injection lifting module and a needle cleaning assembly are provided on the lifting mounting plate. An injection needle is provided on the output end of the injection lifting module. One end of the injection needle is externally connected to an injection pump. The liquid injection lateral movement module is used to drive the liquid injection needle to move along the length direction of the hopper. The liquid injection lifting module can drive the liquid injection needle to extend into the material tank. The liquid injection needle is used to inject liquid medicine into the material tank. The liquid injection lifting module can also drive the liquid injection needle to connect with the needle tube cleaning assembly. The needle tube cleaning assembly is used to clean the liquid injection needle.

2. The liquid injection mechanism of the HE staining machine according to claim 1, characterized in that: The liquid injection transverse movement module includes a liquid injection transverse movement fixing base, which is connected to the liquid injection mounting frame. The liquid injection transverse movement fixing base is provided with a lead screw assembly and a liquid injection transverse movement motor. The output end of the liquid injection transverse movement motor is connected to the lead screw assembly. A liquid injection transverse movement slider is slidably provided on the liquid injection transverse movement fixing base. The liquid injection transverse movement slider is connected to the lead screw assembly. The lifting mounting plate is connected to the liquid injection transverse movement slider.

3. The liquid injection mechanism of the HE staining machine according to claim 1, characterized in that: The liquid injection lifting module includes a liquid injection lifting motor, which is connected to the lifting mounting plate. The lifting mounting plate is provided with a liquid injection lifting driven wheel, and the output end of the liquid injection lifting motor is provided with a liquid injection lifting drive wheel. A liquid injection lifting transmission belt is fitted on the liquid injection lifting drive wheel and the liquid injection lifting driven wheel. A liquid injection lifting slider is provided on the liquid injection lifting transmission belt, and the liquid injection needle is connected to the liquid injection lifting slider.

4. The liquid injection mechanism of the HE staining machine according to claim 3, characterized in that: The lifting mounting plate is equipped with a liquid injection lifting guide rail, and the liquid injection lifting slider is slidably engaged with the liquid injection lifting guide rail.

5. The liquid injection mechanism of the HE staining machine according to claim 3, characterized in that: The lifting mounting plate is equipped with a positioning sensor, and the liquid injection lifting slider is equipped with a detection lever, which can be connected to the positioning sensor.

6. The liquid injection mechanism of the HE staining machine according to any one of claims 1-5, characterized in that: The syringe cleaning assembly includes a cleaning mounting frame connected to the lifting mounting plate. A cleaning tank is provided on the cleaning mounting frame. The cleaning tank has a needle hole that passes through the upper and lower end faces of the cleaning tank. The injection needle can pass through the needle hole and is in clearance fit with the needle hole. The cleaning tank is provided with an inlet connector and an outlet connector on its side wall. The inlet connector and the outlet connector are respectively connected to the needle hole. The inlet connector is connected to the cleaning liquid, and the outlet connector is connected to the negative pressure suction device.

7. The liquid injection mechanism of the HE staining machine according to claim 6, characterized in that: The cleaning tank is made of flexible material.

8. The liquid injection mechanism of the HE staining machine according to claim 6, characterized in that: The lower end face of the injection needle is a sealed structure, and the outlet hole of the injection needle is located on the side wall of the injection needle.

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