Platelet-rich plasma extraction device

Abstract

The utility model discloses a kind of platelet-rich plasma extraction devices, including base, vertical slide rail, centrifugal tube seat, piston rod seat, outer tube seat and platen assembly etc. The utility model is accurate, independently controls the lifting of PRP centrifugal tube and extraction assembly piston rod by double lifting assembly, respectively for accurate adjustment demarcation liquid level position and uniform speed suction PRP, solve the problem of big error of traditional manual operation, can effectively avoid the common red blood cell mixing in manual suction and PRP waste, make PRP extraction standardization degree close to automation equipment. Moreover, the utility model is combined with ordinary centrifuge to be used, i. e. PRP can be prepared, and the equipment cost is low. By replacing centrifugal tube seat component, it can be adapted to various specifications PRP centrifugal tube. In addition, it also has man-machine efficiency design.

Description

Technical Field

[0001] This utility model relates to the field of blood separation equipment technology, specifically to a platelet-rich plasma extraction device. Background Technology

[0002] Since the mid-1990s, platelet-rich plasma (PRP) has been widely used in medical surgery, bone disease treatment, and cosmetic procedures, demonstrating excellent therapeutic effects in disease prevention and rehabilitation. Therefore, there is an urgent need for a convenient and rapid method to extract highly concentrated, high-quality PRP from blood.

[0003] PRP preparation involves two steps: centrifugation and aspiration. While some fully automated equipment integrating centrifugation and aspiration has emerged, the combination of centrifugation and manual aspiration remains the mainstream method. Centrifugation is performed by a centrifuge, while aspiration is achieved manually using a syringe. This method cannot completely eliminate the influence of human operation, resulting in problems such as visual errors due to PRP identification, inaccurate extraction actions, substandard PRP concentration and quality, and slow preparation speed. Furthermore, it fails to achieve standardized operation and process normalization.

[0004] The applicant's prior patent application (application number: 202421799597.6, application date: 2024.07.29) discloses a consumable for automated PRP centrifugal extraction, including an outer tube, a top cover, a base, and a built-in central liquid extraction tube. The top cover has an injection port, a suction port, and a vent. The upper end of the central liquid extraction tube is connected to the suction port, and the lower end forms a liquid extraction port inside the outer tube. A sealed piston is provided inside the lower end of the outer tube, and an operation port is provided on the base. In addition, another patent application of the applicant (application number: 202320686982.9, application date: 2023.03.31) also discloses a syringe-type PRP extraction assembly, which is composed of a syringe, a needle, and a conduit, used to replace a regular syringe.

[0005] Therefore, the applicant hopes to develop a semi-automatic PRP separation and extraction device based on the aforementioned centrifuge tube consumables and extraction components, to replace the traditional method of manual syringe aspiration. Utility Model Content

[0006] To overcome the shortcomings of manual aspiration in the traditional PRP preparation process, this invention provides a platelet-rich plasma extraction device.

[0007] The technical solution adopted by this utility model is as follows: A platelet-rich plasma extraction device includes: a base; a vertical slide rail, vertically installed on the base; a centrifuge tube seat and a first lifting assembly, the centrifuge tube seat having a centrifuge tube, the first lifting assembly having a first knob and a first transmission mechanism, the first lifting assembly being installed between the centrifuge tube seat and the vertical slide rail; a piston rod seat and a second lifting assembly, the piston rod seat having a piston ear groove, the second lifting assembly having a second knob and a second transmission mechanism, the second lifting assembly being installed between the piston rod seat and the vertical slide rail; an outer cylinder seat and a pressure plate assembly, fixed on the vertical slide rail, the outer cylinder seat having an outer cylinder groove, the pressure plate assembly having a centrifuge tube pressure plate and a needle retaining plate groove; the piston ear groove, the outer cylinder groove, the needle retaining plate groove, the centrifuge tube pressure plate, and the centrifuge tube are arranged sequentially from top to bottom.

[0008] Preferably, the centrifuge tube holder is a detachable structure, and the inner diameter of the centrifuge tube is adapted to the piston bottom cover of the PRP centrifuge tube.

[0009] Preferably, the centrifuge tube has a conical top post at its bottom center, which is adapted to the conical bottom of the piston cover.

[0010] Preferably, the upper part of the outer cylinder groove is provided with an outer cylinder ear slot, and the middle part is provided with a disassembly groove that is recessed to both sides.

[0011] Preferably, the pressure plate assembly further includes an upper clamping plate, the gap between the upper clamping plate and the centrifuge tube pressure plate forms the needle clamping plate groove, and both the upper clamping plate and the centrifuge tube pressure plate are provided with U-shaped grooves of the same shape.

[0012] Preferably, the upper clamping plate is provided with positioning beads that are adapted to the positioning holes on the needle plate of the extraction component.

[0013] Preferably, the center of the piston ear groove and the center of the outer cylinder groove are the first center line, and the center of the needle plate groove and the center of the centrifuge tube are the second center line, with the first center line and the second center line being staggered.

[0014] Preferably, it further includes: a horizontal slide rail mounted on the base; preferably, an adjusting seat and a sliding assembly, wherein the adjusting seat serves as a mounting platform for the vertical slide rail, and the sliding assembly has a third knob and a third transmission mechanism, and the sliding assembly is installed between the adjusting seat and the horizontal slide rail.

[0015] Preferably, the first transmission mechanism, the second transmission mechanism, and the third transmission mechanism adopt a lead screw and nut mechanism, a gear and rack mechanism, a worm gear mechanism, or a winding mechanism.

[0016] This utility model has the following beneficial effects: 1. Precise control: The design of vertical slide rail and dual lifting components enables independent and precise control of PRP centrifuge tubes and syringes. The knob, combined with a high-precision transmission mechanism, replaces pure manual operation, accurately adjusting the position of the dividing liquid level and the degree of aspiration, effectively avoiding the common problems of red blood cell contamination and PRP waste in manual aspiration. 2. Compatible with traditional centrifuges: It achieves its functions by relying on existing ordinary centrifuges. Compared with fully automatic PRP preparation equipment, the equipment cost is low, and the standardization of PRP extraction is close to the performance indicators of automated equipment. 3. Simple positioning operation: The centrifuge tube and PRP centrifuge tube are compatible with each other and are centered and positioned by the internal conical top column. During the rise of the centrifuge tube, it ensures that the needle is accurately inserted into the center tube of the PRP centrifuge tube. The positioning is accurate and the operation is simple. 4. Wide applicability: The centrifuge tube holder and the first lifting assembly are bolted and detachable structures. By replacing the centrifuge tube holder with different specifications, it can be used with PRP centrifuge tubes of different specifications. 5. User-friendly human-machine interface: Without keeping the entire device stationary, the horizontal sliding of the adjustment seat can adjust the horizontal position of the operating station, making it convenient for operators of different heights and arm spans to operate. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the external appearance of an embodiment of the present utility model.

[0018] Figure 2 This is a partial exploded view of an embodiment of the present invention.

[0019] Figure 3 This is a cross-sectional view of the centrifuge tube holder in an embodiment of this utility model.

[0020] Figure 4 This is a three-dimensional schematic diagram of the pressure plate assembly in an embodiment of this utility model.

[0021] Figure 5 This is a front view schematic diagram of the pressure plate assembly in an embodiment of this utility model.

[0022] Figure 6 This is a schematic diagram of the syringe and PRP centrifuge tube used in the embodiments of this utility model.

[0023] Figure 7 This is a schematic diagram of the usage state of an embodiment of this utility model.

[0024] Base 1; Vertical slide rail 2; Centrifuge tube base 3, centrifuge tube 3.1, conical top column 3.2; First lifting assembly 4, first knob 4.1; Piston rod seat 5, piston lug groove 5.1; Second lifting assembly 6, second knob 6.1; Outer cylinder seat 7, outer cylinder groove 7.1, outer cylinder ear slot 7.2, disassembly groove 7.3; Pressure plate assembly 8, centrifuge tube pressure plate 8.1, needle clamping plate groove 8.2, upper clamping plate 8.3, U-shaped groove 8.4, positioning ball 8.5; Horizontal slide rail 9; Adjustment seat 10; Sliding assembly 11, third knob 11.1; PRP centrifuge tube 12, piston bottom cap 12.1; Extraction assembly 13, piston rod 13.1, outer cylinder 13.2, needle clamp 13.3, needle 13.4, positioning hole 13.5, guide tube 13.6; First centerline L1, second centerline L2. Detailed Implementation

[0025] The present invention will be further described below with reference to the embodiments and accompanying drawings.

[0026] In the embodiments, such as Figures 1-7 The image shows a platelet-rich plasma (PRP) extraction device, comprising: a base 1; a vertical slide rail 2, vertically mounted on the base 1; a centrifuge tube holder 3 and a first lifting assembly 4, the centrifuge tube holder 3 having a centrifuge tube 3.1, the first lifting assembly 4 having a first knob 4.1 and a first transmission mechanism, the first lifting assembly 4 being installed between the centrifuge tube holder 3 and the vertical slide rail 2; a piston rod holder 5 and a second lifting assembly 6, the piston rod holder 5 having a piston ear groove 5.1, the second lifting assembly 6 having a second knob 6.1 and a second transmission mechanism, the second lifting assembly 6 being installed between the piston rod holder 5 and the vertical slide rail 2; an outer cylinder holder 7 and a pressure plate assembly 8, fixed on the vertical slide rail 2, the outer cylinder holder 7 having an outer cylinder groove 7.1, the pressure plate assembly 8 having a centrifuge tube pressure plate 8.1 and a needle clamping plate groove 8.2; the piston ear groove 5.1, the outer cylinder groove 7.1, the needle clamping plate groove 8.2, the centrifuge tube pressure plate 8.1, and the centrifuge tube 3.1 are arranged sequentially from top to bottom. This embodiment utilizes a dual independent lifting assembly consisting of a first lifting assembly 4 and a second lifting assembly 6, in conjunction with a vertical slide rail 2, to achieve precise separate control of the piston rod of the PRP centrifuge tube 12 and the extraction assembly 13. A knob-driven mechanism replaces purely manual operation, accurately adjusting the liquid level and suction force. This solves the problem of large errors in traditional manual operation and effectively avoids the common issues of red blood cell contamination and PRP waste during manual aspiration, bringing the standardization of PRP extraction close to the performance indicators of automated equipment. Furthermore, as a semi-automatic device, it can be used with existing centrifuges, with significantly lower costs than fully automatic equipment, while simultaneously improving operational standardization.

[0027] In the embodiments, such asFigure 3 As shown, the centrifuge tube holder 3 is a detachable structure; the inner diameter of the centrifuge tube 3.1 is adapted to the piston bottom cover 12.1 of the PRP centrifuge tube 12; a conical top post 3.2 is provided at the center of the bottom of the centrifuge tube 3.1, which is adapted to the conical bottom of the piston bottom cover 12.1. The adaptation of the inner diameter of the centrifuge tube 3.1 to the piston bottom cover 12.1 ensures that the PRP centrifuge tube 12 remains vertically stable during lifting and lowering, avoiding misoperation caused by needle 13.4 deviation. The conical top post 3.2 fits into the conical bottom of the piston bottom cover 12.1, realizing a self-centering function, forcibly correcting the center position of the PRP centrifuge tube 12, and ensuring that the needle 13.4 is accurately inserted into the central liquid collection tube. The centrifuge tube holder 3 is installed to the first lifting assembly 4 by bolts and is a detachable structure, which facilitates the individual replacement of centrifuge tubes 3.1 of different specifications to adapt to different specifications of PRP centrifuge tubes 12, thereby improving the versatility of the device.

[0028] In the embodiments, such as Figure 2 As shown, the upper part of the outer cylinder groove 7.1 is provided with an outer cylinder ear slot 7.2, and the middle part is provided with a disassembly groove 7.3 that is recessed to both sides. The outer cylinder ear slot 7.2 is used to position and lock the outer cylinder 13.2 to prevent loosening or displacement during operation. The disassembly grooves 7.3 on both sides provide operating space. When it is necessary to disassemble and extract the component 13, the operator can put his index finger and thumb into the disassembly groove 7.3 to achieve quick disassembly and assembly without tools, which is very convenient.

[0029] In the embodiments, such as Figure 4 , Figure 5 As shown, the pressure plate assembly 8 also includes an upper clamping plate 8.3. The gap between the upper clamping plate 8.3 and the centrifuge tube pressure plate 8.1 forms a needle retaining groove 8.2. Both the upper clamping plate 8.3 and the centrifuge tube pressure plate 8.1 are provided with U-shaped grooves 8.4 of the same shape. The upper clamping plate 8.3 and the centrifuge tube pressure plate 8.1 are installed with screws. The adjustable needle retaining groove 8.2 is formed by adding or removing shims to accommodate needle retaining plates 13.3 of different thicknesses, thus providing wide adaptability. The U-shaped groove 8.4 is designed to avoid obstruction, facilitating the smooth passage of the needle 13.4 from the extraction assembly 13.

[0030] In the embodiments, such as Figure 4 , Figure 5As shown, the upper clamping plate 8.3 is provided with positioning beads 8.5, which are adapted to the positioning holes 13.5 on the needle holder 13.3 of the extraction component 13. There are two positioning beads 8.5, which are respectively arranged on both sides of the U-shaped groove 8.4. After engaging with the positioning holes 13.5 on the two needle holders 13.3, they form a mechanical interlock to ensure that the needle holder 13.3 is accurately installed and to eliminate misoperation caused by the misalignment of the needle 13.4 during operation. The positioning beads 8.5 have two advantages: first, they are elastic, allowing the needle holder 13.3 to be smoothly inserted or removed, avoiding jamming with the needle holder groove 8.2; second, the "click" tactile and audible feedback of the positioning beads 8.5 can indicate that the assembly is in place, making the operation feedback clear.

[0031] In the embodiments, such as Figure 6 As shown, the center of the piston ear groove 5.1 and the outer cylinder groove 7.1 is the first center line L1, and the center of the needle plate groove 8.2 and the centrifuge tube 3.1 is the second center line L2. The first center line L1 and the second center line L2 are staggered. Precision machining ensures the coaxiality of each component, forming a vertical operating reference axis. Even with slight wear of the slide rail due to high-frequency use, high precision is maintained. The staggered arrangement of the first center line L1 and the second center line L2 optimizes the overall layout of the device, reduces its height, and allows the operator's line of sight to focus on a smaller area, conforming to ergonomic design principles.

[0032] In the embodiments, such as Figure 1 , Figure 2 , Figure 7 As shown, it also includes: a horizontal slide rail 9, mounted on the base 1; an adjusting seat 10 and a sliding assembly 11. The adjusting seat 10 serves as the mounting platform for the vertical slide rail 2, and the sliding assembly 11 has a third knob 10.1 and a third transmission mechanism. The sliding assembly 11 is installed between the adjusting seat 10 and the horizontal slide rail 9. The sliding direction of the adjusting seat 10 is generally set perpendicular to the operator's front direction. The operator can adjust the vertical slide rail 2 to the optimal field of vision according to their sitting or standing posture, reducing muscle fatigue caused by long-term operation, and can also adapt to the ergonomic needs of operating tables with different heights from 60cm to 120cm.

[0033] In this embodiment, the first, second, and third transmission mechanisms employ lead screw and nut mechanisms, gear and rack mechanisms, worm gear mechanisms, or winding mechanisms. The transmission mechanisms are selected to convert rotary motion into linear motion. Lead screw and nut mechanisms and worm gear mechanisms have self-locking functions, while gear and rack mechanisms have a compact structure and can be selected according to actual conditions. A combination of multiple transmission mechanisms (such as gear transmission-worm gear) can also be used. In this embodiment, the first knob 4.1 and the second knob 6.1 can have larger diameters to increase the transmission ratio and improve the accuracy of manual operation.

[0034] likeFigure 7 The following is a description of the operation steps of the extraction device in this embodiment: Step 1. Equipment Preparation Place the device on a horizontal workbench and ensure that the base 1 is stable. If the operating position needs to be adjusted, rotate the third knob 11.1 to move the adjusting seat 10 through the horizontal slide rail 9 so that the vertical slide rail 2 is in the appropriate position.

[0035] Step 2. Install 12 PRP centrifuge tubes After centrifugation, vertically insert the PRP centrifuge tube 12 into the centrifuge tube holder 3.1 of the centrifuge tube holder 3. Ensure that the bottom of the centrifuge tube 12 is in contact with the conical top post 3.2 at the bottom of the centrifuge tube holder 3.1 to achieve automatic centering.

[0036] Step 3. Install extraction component 13 Insert the outer cylinder 13.2 of the extraction component 13 into the outer cylinder groove 7.1 of the outer cylinder seat 7, ensuring that the outer cylinder ear is engaged in the outer cylinder ear groove 7.2. At the same time, rotate the second knob 6.1 to adjust the position of the piston rod seat 5, so that the ear of the piston rod 13.1 is engaged in the piston ear groove 5.1 of the piston rod seat 5.

[0037] Insert the needle holder 13.3 of the extraction component 13 into the needle holder slot 8.2 of the pressure plate component 8, ensuring that the positioning hole 13.5 is aligned with the positioning ball 8.5 of the upper clamping plate 8.3.

[0038] Step 4. Adjust the dividing liquid level Rotate the first knob 4.1, and the centrifuge tube seat 3 will rise along the vertical slide rail 2 through the first lifting component 4 until the top cover of the PRP centrifuge tube 12 contacts the lower end face of the centrifuge tube pressure plate 8.1, and at the same time the needle 13.4 is inserted into the central tube of the PRP centrifuge tube 12.

[0039] Key action: Continue to slowly rotate the first knob 4.1, causing the conical top column 3.2 inside the centrifuge tube holder 3 to push the piston bottom cover 12.1 of the PRP centrifuge tube 12 upwards, gradually bringing the boundary liquid level between the red blood cell layer and the PRP layer closer to the central tube opening. Observe the liquid level position through the transparent PRP centrifuge tube 12. Stop rotating when the boundary line is aligned with the central tube opening (or the boundary line is at a preset height of 1-2 mm above or below the central tube opening).

[0040] Step 5. Extract PRP Key action: Rotate the second knob 6.1 slowly and evenly, causing the piston rod seat 5 to rise slowly via the second lifting assembly 6. Each rotation corresponds to a uniform rise of the piston rod 13.1, achieving uniform aspiration. Observe the color of the blood components in the transparent catheter 13.6 until the catheter 13.6 is entirely composed of plasma, indicating that all PRP has been aspirated.

[0041] Step 6. Disassembly Rotate the first knob 4.1 in the reverse direction to lower the centrifuge tube holder 3 and remove the PRP centrifuge tube 12. Remove the extraction assembly 13 and rotate the second knob 6.1 in the reverse direction to reset the piston rod holder 5.

[0042] Obviously, the above embodiments of this utility model are merely examples for illustrating the present utility model, and are not intended to limit the implementation of the present utility model. Other obvious variations or modifications derived from the essential spirit of the present utility model still fall within the protection scope of the present utility model.

Claims

1. A platelet-rich plasma extraction device, characterized in that, include: Base (1); A vertical slide rail (2) is vertically mounted on the base (1); Centrifuge tube holder (3) and first lifting assembly (4), the centrifuge tube holder (3) has centrifuge tube (3.1), the first lifting assembly (4) has a first knob (4.1) and a first transmission mechanism, the first lifting assembly (4) is installed between the centrifuge tube holder (3) and the vertical slide rail (2); The piston rod seat (5) and the second lifting assembly (6) are provided. The piston rod seat (5) has a piston ear groove (5.1). The second lifting assembly (6) has a second knob (6.1) and a second transmission mechanism. The second lifting assembly (6) is installed between the piston rod seat (5) and the vertical slide rail (2). The outer cylinder seat (7) and the pressure plate assembly (8) are fixed on the vertical slide rail (2). The outer cylinder seat (7) has an outer cylinder groove (7.1), and the pressure plate assembly (8) has a centrifuge tube pressure plate (8.1) and a needle clamping plate groove (8.2). The piston ear slot (5.1), the outer cylinder slot (7.1), the needle plate slot (8.2), the centrifuge tube pressure plate (8.1), and the centrifuge tube (3.1) are arranged sequentially from top to bottom.

2. The platelet-rich plasma extraction device according to claim 1, characterized in that, The centrifuge tube holder (3) is a detachable structure, and the inner diameter of the centrifuge tube (3.1) is adapted to the piston bottom cover (12.1) of the PRP centrifuge tube (12).

3. The platelet-rich plasma extraction device according to claim 2, characterized in that, The centrifuge tube (3.1) has a conical top post (3.2) at its bottom center, which is adapted to the conical bottom of the piston bottom cover (12.1).

4. The platelet-rich plasma extraction device according to claim 1, characterized in that, The outer cylinder groove (7.1) has an outer cylinder ear slot (7.2) at the top and a disassembly groove (7.3) that is recessed to both sides in the middle.

5. The platelet-rich plasma extraction device according to claim 1, characterized in that, The pressure plate assembly (8) also includes an upper clamping plate (8.3), and the gap between the upper clamping plate (8.3) and the centrifuge tube pressure plate (8.1) forms the needle clamping plate groove (8.2). Both the upper clamping plate (8.3) and the centrifuge tube pressure plate (8.1) are provided with U-shaped grooves (8.4) with the same shape.

6. The platelet-rich plasma extraction device according to claim 5, characterized in that, The lower surface of the upper clamping plate (8.3) is provided with a positioning ball (8.5), which is adapted to the positioning hole (13.5) on the needle plate (13.3) of the extraction component (13).

7. The platelet-rich plasma extraction device according to claim 1, characterized in that, The center of the piston ear groove (5.1) and the outer cylinder groove (7.1) is the first center line (L1), and the center of the needle plate groove (8.2) and the centrifuge tube (3.1) is the second center line (L2). The first center line (L1) and the second center line (L2) are staggered.

8. The platelet-rich plasma extraction device according to claim 1, characterized in that, It also includes: A horizontal slide rail (9) is mounted on the base (1); Adjustment seat (10) and sliding assembly (11), the adjustment seat (10) serves as the mounting platform for the vertical slide rail (2), the sliding assembly (11) has a third knob (10.1) and a third transmission mechanism, the sliding assembly (11) is installed between the adjustment seat (10) and the horizontal slide rail (9).

9. The platelet-rich plasma extraction device according to claim 8, characterized in that, The first transmission mechanism, the second transmission mechanism, and the third transmission mechanism adopt a lead screw and nut mechanism, a gear and rack mechanism, a worm gear mechanism, or a winding mechanism.

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