A prp preparation connection structure
Patent Information
- Application Number
- CN202522342638.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-04
- Publication Date
- 2026-09-22
- Estimated Expiration
- 2035-11-04
AI Technical Summary
单级注射器结构虽然操作简单,但血小板富集效率较低,无法满足一些对血小板浓度要求较高的治疗需求
1.本申请通过构建一个封闭、集成的PRP制备系统,确保血液离心后能直接通过注射器在无菌环境下抽吸分层后的PRP。简化了操作流程,减少了样本污染风险,提高了PRP提取的效率和安全性,为后续临床应用提供了便利。
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Figure CN224778257U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical device connection technology, and in particular to a PRP fabrication connection structure. Background Technology
[0002] Currently, in the field of medical device technology, autologous platelet-rich plasma (PRP) is increasingly widely used in orthopedic surgery due to its unique ability to promote tissue repair and healing. It extracts a high concentration of platelets from the patient's own blood using centrifugation technology, demonstrating significant value in the adjuvant treatment of fracture surgery.
[0003] In existing technologies, several different techniques are mainly used to prepare PRP. Single-stage syringes are a common method; their operation is relatively simple, requiring no complex equipment or specialized skills, and can be quickly mastered by ordinary medical personnel. Centrifuge tubes improve platelet enrichment efficiency to some extent, as centrifugal force allows for more effective platelet separation. However, with traditional centrifuge tubes, after centrifugation, operators need to manually insert pipettes or syringes into the tube for aspiration. During this process, visual positioning of the PRP layer is required, and hand tremors can easily occur due to the suspended hand, potentially disturbing the blood layer boundary and causing PRP to mix with red blood cells or PPP. Furthermore, the open operating environment increases the risk of sample contamination from air exposure.
[0004] Existing technologies have significant shortcomings. While single-stage syringes are simple to operate, their platelet enrichment efficiency is low, failing to meet the needs of some treatments requiring high platelet concentrations. Centrifuge tubes are complex to operate and prone to blood contamination during use, increasing the risk of infection for patients. Furthermore, existing devices are not adequately designed for sterility and single-use, posing a risk of cross-infection and a potential threat to patient health. Utility Model Content
[0005] To overcome the shortcomings of the existing technology, this application provides a PRP preparation connection structure that achieves efficient preparation through the cooperation of centrifuge tubes, syringes, and intermediate connectors. The centrifuge tubes provide space for blood centrifugation, the syringes precisely aspirate the layered PRP, and the intermediate connectors ensure a sealed connection between the two. Its core effect is that the first piston head ensures the centrifugation channel is sealed, preventing sample contamination and leakage, while simultaneously allowing the syringe to stably extend into the channel, improving the accuracy and ease of operation of PRP aspiration.
[0006] This application is achieved through the following technical solution: A PRP fabrication connection structure includes: Centrifuge tube, wherein the centrifuge tube has a centrifugation channel inside for containing and centrifuging blood samples; A syringe that can be inserted into the centrifugation channel for aspirating the PRP that has separated into layers after centrifugation; An intermediate connector is sleeved on the outer periphery of the syringe, and a connection port is provided at the end of the intermediate connector. The connection port is connected to the suction end of the syringe and the centrifugal channel respectively. A first piston head is installed on the outer wall of the end of the intermediate connector, and the first piston head is slidably connected to the centrifugal channel in a sealed manner.
[0007] By adopting the above technical solution, the entire assembly of "intermediate connector plus syringe" can move stably and smoothly up and down within the centrifuge tube like a piston, due to the sealed sliding of the first piston head against the inner wall of the centrifuge tube. This allows the operator to precisely position the syringe needle onto the narrow PRP layer, avoiding the shaking and inaccurate positioning caused by manual suspension. The sealed sliding connection isolates the air above the piston head from the blood layers (PRP, PPP, RBC) below, preventing contamination of the PRP by airborne impurities or bacteria. Simultaneously, the stable downward pressure process reduces disturbance to each layer, preventing premature activation of the PRP and mixing with red blood cells, thus ensuring the quality and purity of the PRP. The piston-like structure standardizes each operation. The operator can stably press the piston head down to the interface between the PPP and PRP before aspiration, greatly improving the PRP extraction rate and ensuring consistency of results between different operations.
[0008] Optionally, the first piston head is a cap-type piston head, and the intermediate connecting member includes a first connecting part, a conical sealing part, and a suction part connected in sequence. The outer wall of the first connecting part is sealed to the inner wall of the cap-type piston head, and the conical sealing part elastically abuts against the inner wall of the cap-type piston head. One end of the suction part passes through the connecting port and extends to the outside of the first piston head.
[0009] By adopting the above technical solutions, "sealed connection" and "elastic contact" provide double protection, reducing the risk of leakage between intermediate connecting parts and piston head, and ensuring the airtightness of the entire piston system.
[0010] Optionally, a limiting portion is provided at the end of the first connecting portion away from the conical sealing portion, the peripheral side of the limiting portion and the peripheral side of the first connecting portion are located on the same circumference, and the end face of the limiting portion abuts against the end face of the first connecting portion away from the conical sealing portion.
[0011] By adopting the above technical solution, the limiting part can prevent the intermediate connecting part from being over-push into the cap-type piston head during assembly. It ensures that the intermediate connecting part is always installed to the correct, preset depth, thereby guaranteeing that the conical sealing part can form the optimal elastic sealing effect, simplifying the production assembly process and improving product consistency.
[0012] Optionally, an auxiliary pull-out part is connected to the side of the limiting part away from the first connecting part, and the auxiliary pull-out part is sleeved on the outer periphery of the syringe.
[0013] By adopting the above technical solution, the auxiliary pull-out section provides a convenient area for holding and operation. The operator can directly pinch or push this section with their fingers to control the movement of the entire piston assembly within the centrifuge tube, rather than directly pushing or pulling the syringe itself. This makes operation more comfortable and stable, further reducing the possibility of vibration.
[0014] Optionally, an auxiliary window is provided on the outer wall of the auxiliary pull-out part.
[0015] By adopting the above technical solution, the operator can see the scale of the internal syringe through the window, facilitating real-time monitoring of the volume of PRP drawn. Without compromising structural strength, the window reduces plastic usage and lowers production costs.
[0016] Optionally, a first groove is provided between the conical sealing part and the suction part, and the groove wall of the first groove engages with the inner wall of the connection port.
[0017] By adopting the above technical solution, the snap-fit structure effectively prevents the intermediate connecting component from accidentally sliding out or being pulled out of the piston head, providing a stronger physical locking than simple friction fit or sealing contact, and improving the connection reliability of the component. This slot also serves a positioning function, ensuring that the position of the intermediate connecting component relative to the piston head is fixed.
[0018] Optionally, the outer wall of the first piston head is provided with a sealing strip, which is slidably connected to the centrifuge tube; at least two sealing strips are provided along the axial direction.
[0019] By employing the above technical solutions, single-seal applications may fail due to manufacturing errors or wear. Adding two or more sealing strips can create redundant or tiered seals. Even if one seal leaks slightly, another can effectively prevent leakage, significantly improving the airtightness between the piston head and the centrifuge tube. Multiple sealing strips also provide better guidance, making the piston move more smoothly within the centrifuge tube and reducing wobbling.
[0020] Optionally, the suction part is provided with a second connecting part in the direction of the first connecting part, and the suction end of the syringe is provided with a third connecting part, wherein the inner wall of the third connecting part is threadedly connected to the outer wall of the second connecting part.
[0021] By employing the above technical solution, the threaded connection is far more robust than a simple plug-in connection, preventing accidental separation of the syringe from the intermediate connector during suction or push-pull operations. The use of a standard threaded interface ensures compatibility with most standard syringes on the market, improving product versatility. The threaded connection itself also provides a good seal, preventing air leakage at the connection point during suction.
[0022] Optionally, the first piston head is made of an elastic material.
[0023] By adopting the above technical solution and using elastic materials (such as silicone and rubber) to manufacture the piston head, it can better adapt to minute changes and tolerances in the inner diameter of the centrifuge tube, achieving a tighter and more reliable seal through its own elastic deformation. At the same time, the elastic material also provides a smoother sliding experience and reduces friction.
[0024] Optionally, the suction end of the centrifuge tube may be detachably connected to a sealing cap.
[0025] By employing the above technical solution, it is ensured that blood will not splash out during high-speed centrifugation. This protects the blood sample from external environmental contamination before and after centrifugation. The detachable feature means that after centrifugation and before PRP aspiration, it can be easily removed for insertion into the connection structure of this invention. This is an essential component in a complete PRP preparation process.
[0026] In summary, this application includes at least one of the following beneficial technical effects: 1. This application constructs a closed, integrated PRP preparation system that ensures that PRP, after blood centrifugation, can be directly aspirated in a sterile environment using a syringe. This simplifies the operation process, reduces the risk of sample contamination, and improves the efficiency and safety of PRP extraction, facilitating subsequent clinical applications.
[0027] 2. This application ensures a tight seal inside the centrifuge tube through the elastic contact between the conical sealing part and the cap-type piston head. This improves the adaptability and pressure resistance of the connectors, prevents liquid leakage during centrifugation or aspiration, simplifies the assembly process, and enhances the reliability and service life of the equipment.
[0028] 3. This application ensures a fixed connection between components through the end-face contact design of the limiting part. This improves the stability of the overall structure and operational safety, avoids suction errors or contamination caused by component sliding, and further optimizes the accuracy and consistency of PRP preparation. Attached Figure Description
[0029] Figure 1 This is a schematic diagram of the centrifuge tube described in Embodiment 1; Figure 2This is a schematic diagram of the syringe described in Embodiment 1; Figure 3 yes Figure 2 A magnified view of part A in the diagram; Figure 4 yes Figure 2 A magnified view of part B in the diagram.
[0030] In the diagram: 1. Centrifuge tube; 11. Centrifuge channel; 2. Syringe; 21. Suction end; 22. Third connecting part; 3. Intermediate connecting piece; 31. Connecting port; 32. First piston head; 321. Cap-type piston head; 322. Sealing strip; 33. First connecting part; 34. Conical sealing part; 35. Suction part; 36. Limiting part; 37. Auxiliary pull-out part; 371. Auxiliary window; 38. First slot; 39. Second connecting part; 4. Sealing cap. Detailed Implementation
[0031] The following will be combined with the appendix Figure 1-4 The technical solutions of the various embodiments of this application have been clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.
[0032] Reference Figures 1-2 This application discloses a PRP preparation connection structure, including a centrifuge tube 1, a syringe 2, and an intermediate connector 3. The centrifuge tube 1 has a centrifugation channel 11 for containing and centrifuging blood samples. The syringe 2 can be inserted into the centrifugation channel 11 to aspirate the PRP that has been separated into layers after centrifugation. The intermediate connector 3 is sleeved on the outer periphery of the syringe 2 and has a connection port 31 at its end. The connection port 31 is connected to the aspiration end 21 of the syringe 2 and the centrifugation channel 11, respectively. A first piston head 32 is installed on the outer wall of the end of the intermediate connector 3, and the first piston head 32 is slidably connected to the centrifugation channel 11.
[0033] Specifically, centrifuge tube 1 is typically made of transparent plastic, such as polypropylene. This material has good chemical stability and corrosion resistance, ensuring that the blood sample is not contaminated during centrifugation. Centrifuge tube 1 is generally cylindrical with an elliptical bottom; this design facilitates the separation of blood into layers under centrifugal force. In practical applications, other shapes of centrifuge tube 1, such as square ones, can also be used, as long as they meet the requirements for containing and centrifuging blood samples. Syringe 2 generally consists of a syringe, plunger, and needle. The syringe is usually made of transparent plastic for easy observation of the amount of PRP aspirated. The plunger is generally made of plastic or metal with graduations for accurate control of the aspirated amount. The needle diameter is selected according to actual needs, generally being relatively thin to minimize damage to the blood's layered structure. In some special cases, a needle-free syringe 2 can also be used to aspirate PRP using pressure.
[0034] Reference Figures 2-3 The first piston head 32 is a cap-type piston head 321. The intermediate connecting member 3 includes a first connecting part 33, a conical sealing part 34, and a suction part 35 connected in sequence. The outer wall of the first connecting part 33 is sealed to the inner wall of the cap-type piston head 321, and the conical sealing part 34 elastically abuts against the inner wall of the cap-type piston head 321. One end of the suction part 35 passes through the connecting port 31 and extends to the outside of the first piston head 32.
[0035] The first connecting part 33 is threaded, and its outer diameter is adapted to the inner diameter of the cap-type piston head 321 to ensure a sealing effect. The first connecting part 33 can be made of rubber or other elastic materials, which can better seal against the inner wall of the cap-type piston head 321. It can also be made of plastic, and a precise machining process can be used to ensure a tight seal with the cap-type piston head 321. The conical sealing part 34 is conical in shape, with its large end facing the first connecting part 33 and its small end facing the suction part 35. This conical design allows for a better sealing effect when it comes into contact with the inner wall of the cap-type piston head 321. The conical sealing part 34 can be made of silicone or other elastic materials, which have good elasticity and sealing performance. It can also be made of rubber, and its hardness and elasticity can be adjusted to meet the sealing requirements. One end of the suction part 35 passes through the connecting port 31 and extends to the outside of the first piston head 32. The suction part 35 is generally a tubular structure, and its inner diameter is adapted to the suction end 21 of the syringe 2 to ensure that the PRP can pass through smoothly. The suction part 35 can be made of plastic or metal. The plastic suction part 35 is lightweight and low cost, while the metal suction part 35 is more robust and durable.
[0036] Reference Figure 2 and Figure 3A limiting part 36 is provided at the end of the first connecting part 33 away from the conical sealing part 34. The peripheral side of the limiting part 36 is located on the same circumference as the peripheral side of the first connecting part 33, and the end face of the limiting part 36 abuts against the end face of the first connecting part 33 away from the conical sealing part 34. The function of the limiting part 36 is to prevent the intermediate connecting part 3 from being over-inserted into the centrifuge tube 1 during use, thus serving as a limiting function. The limiting part 36 is generally a ring structure, and its outer diameter is the same as the outer diameter of the first connecting part 33. The limiting part 36 can be integrally formed with the first connecting part 33, or it can be fixedly connected by means of glue or other methods.
[0037] Reference Figure 2 and Figure 3 An auxiliary pull-out part 37 is connected to the side of the limiting part 36 away from the first connecting part 33. The auxiliary pull-out part 37 is sleeved on the outer periphery of the syringe 2. The auxiliary pull-out part 37 is generally cylindrical, with its inner diameter slightly larger than the outer diameter of the syringe 2, making it easy to fit onto the syringe 2. The function of the auxiliary pull-out part 37 is to facilitate the operator's pull-out operation when drawing PRP, improving the convenience of operation. The auxiliary pull-out part 37 can be made of plastic, and its surface can be provided with anti-slip textures to increase friction.
[0038] Reference Figure 1 and Figure 3 An auxiliary window 371 is provided on the outer wall of the auxiliary pull-out part 37. The function of the auxiliary window 371 is to facilitate observation of the suction situation inside the syringe 2, and also to reduce the weight of the auxiliary pull-out part 37. The shape of the auxiliary window 371 can be rectangular, circular or other shapes, and its size is determined according to actual needs.
[0039] Reference Figure 3 A first groove 38 is provided between the conical sealing part 34 and the suction part 35, and the groove wall of the first groove 38 engages with the inner wall of the connecting port 31. The function of the first groove 38 is to fix the intermediate connecting piece 3 and the first piston head 32 in place, preventing the intermediate connecting piece 3 from separating from the first piston head 32 during the suction process. The width and depth of the first groove 38 are determined according to the size of the connecting port 31, and it is generally formed between the conical sealing part 34 and the suction part 35 using an injection molding process.
[0040] Reference Figure 1 and Figure 3 The outer wall of the first piston head 32 is provided with a sealing strip 322, which is slidably connected to the centrifuge tube 1; at least two sealing strips 322 are provided along the axial direction. The function of the sealing strip 322 is to further enhance the sealing performance between the first piston head 32 and the centrifuge tube 1 and prevent air leakage. The sealing strip 322 can be made of rubber or silicone material, and its shape is generally annular.
[0041] Reference Figure 2 and Figure 3The suction section 35 has a second connecting section 39 facing the first connecting section 33, and the suction end 21 of the syringe 2 has a third connecting section 22. The inner wall of the third connecting section 22 is threadedly connected to the outer wall of the second connecting section 39. This threaded connection makes the connection between the syringe 2 and the intermediate connecting member 3 more secure, preventing the syringe 2 from separating from the intermediate connecting member 3 during suction. The thread specification is determined according to actual needs, and fine threads are generally used to ensure tightness of the connection. The first piston head 32 is made of elastic material.
[0042] Reference Figure 2 and Figure 4 The centrifuge tube 1 has a detachable sealing cap 4 at its suction end 21. The function of the sealing cap 4 is to prevent blood sample leakage during centrifugation and to protect the cleanliness of the inside of the centrifuge tube 1 when not in use. The sealing cap 4 is generally made of plastic and is detachably connected to the centrifuge tube 1 by means of a snap or thread.
[0043] The implementation principle of this embodiment is as follows: During PRP preparation, a blood sample is first placed in centrifuge tube 1 for centrifugation to separate the blood into layers. After centrifugation, the sealing cap 4 is opened, and a syringe 2 equipped with an intermediate connector 3 is inserted into the centrifugation channel 11 of centrifuge tube 1. The first piston head 32 is slidably connected to the centrifugation channel 11, ensuring a tight seal. The syringe plunger 2 is pulled by the auxiliary pull-out part 37, allowing PRP to enter the syringe 2 through the connection port 31 and the aspiration part 35. Due to the special structural design of the intermediate connector 3 and the sealing effect of the first piston head 32, external air is effectively prevented from entering the centrifuge tube 1, preventing damage to the blood layering structure and improving the purity and effectiveness of PRP aspiration. Simultaneously, the connection method between the components ensures the stability and reliability of the entire connection structure, offering significant advantages over existing PRP preparation connection methods and improving the quality and efficiency of PRP preparation.
[0044] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the technical solutions of the embodiments of this application.
Claims
1. A PRP-based connection structure, characterized in that, include: Centrifuge tube (1), the centrifuge tube (1) is provided with a centrifugation channel (11) for containing and centrifuging blood samples. Syringe (2), which can be inserted into the centrifugation channel (11) for aspirating the PRP that has been separated into layers after centrifugation; An intermediate connector (3) is sleeved on the outer periphery of the syringe (2) and the end of the intermediate connector (3) is provided with a connection port (31). The connection port (31) is connected to the suction end (21) of the syringe (2) and the centrifugal channel (11) respectively. A first piston head (32) is installed on the outer wall of the end of the intermediate connector (3). The first piston head (32) is in a sealed sliding connection with the centrifugal channel (11).
2. The PRP fabrication connection structure according to claim 1, characterized in that, The first piston head (32) is a cap-type piston head (321). The intermediate connecting member (3) includes a first connecting part (33), a conical sealing part (34), and a suction part (35) connected in sequence. The outer wall of the first connecting part (33) is sealed to the inner wall of the cap-type piston head (321). The conical sealing part (34) elastically abuts against the inner wall of the cap-type piston head (321). One end of the suction part (35) passes through the connecting port (31) and extends to the outside of the first piston head (32).
3. The PRP fabrication connection structure according to claim 2, characterized in that, The first connecting part (33) is provided with a limiting part (36) at one end away from the conical sealing part (34). The peripheral side of the limiting part (36) is located on the same circumference as the peripheral side of the first connecting part (33). The end face of the limiting part (36) abuts against the end face of the first connecting part (33) away from the conical sealing part (34).
4. The PRP fabrication connection structure according to claim 3, characterized in that, The limiting part (36) is connected to an auxiliary pull part (37) on the side away from the first connecting part (33), and the auxiliary pull part (37) is sleeved on the outer periphery of the syringe (2).
5. The PRP fabrication connection structure according to claim 4, characterized in that, An auxiliary window (371) is provided on the outer wall of the auxiliary pull-out part (37).
6. The PRP fabrication connection structure according to claim 2, characterized in that, A first slot (38) is provided between the conical sealing part (34) and the suction part (35), and the groove wall of the first slot (38) is engaged with the inner wall of the connection port (31).
7. The PRP fabrication connection structure according to claim 2, characterized in that, The outer wall of the first piston head (32) is provided with a sealing strip (322), and the sealing strip (322) is slidably connected to the centrifuge tube (1); at least two sealing strips (322) are provided along the axial direction.
8. The PRP fabrication connection structure according to claim 2, characterized in that, The suction part (35) is provided with a second connecting part (39) in the direction of the first connecting part (33), and the suction end (21) of the syringe (2) is provided with a third connecting part (22). The inner wall of the third connecting part (22) is threadedly connected to the outer wall of the second connecting part (39).
9. The PRP fabrication connection structure according to claim 1, characterized in that, The first piston head (32) is made of an elastic material.
10. The PRP fabrication connection structure according to claim 1, characterized in that, The centrifuge tube (1) has a detachable sealing cap (4) attached to the suction end (21).