Composition of reduced glutathione and ceramide, coated with polyphenols

A polyphenol-coated glutathione and ceramide composition addresses hydrolysis and absorption issues by using a multi-layer coating to maintain efficacy and improve taste, enhancing absorption and utilization.

DE202025102247U1Active Publication Date: 2025-06-18TOSAKA INT
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Patent Information

Application Number
DE202025102247
Authority / Receiving Office
DE · DE
Patent Type
Utility models
Current Assignee / Owner
Filing Date
2025-04-24
Publication Date
2025-06-18
Estimated Expiration
2035-04-30

AI Technical Summary

Technical Problem

Existing dietary supplements containing glutathione and ceramide face challenges such as glutathione hydrolysis by digestive enzymes and ceramide's difficulty in absorption without a fat-soluble carrier, leading to reduced efficacy and unpleasant taste.

Method used

A composition of reduced glutathione and ceramide coated with polyphenols, featuring a multi-layer structure with a polyphenol and fat-soluble coating to protect against digestive enzymes and enhance absorption.

Benefits of technology

The coating structure preserves the integrity and efficacy of glutathione and ceramide, improving absorption and utilization rates while masking unpleasant odors and enhancing taste acceptance.

✦ Generated by Eureka AI based on patent content.

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Abstract

Composition of reduced glutathione and ceramide coated with polyphenols (10), comprising: a main body (20) containing reduced glutathione and ceramide; a first coating layer (30) consisting of at least one polyphenol material and coating the surface of the main body (20).
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Description

Field of the InventionThe present invention relates to a food product having an encapsulating structure, and more particularly to a composition of reduced glutathione and ceramide enveloped with polyphenols.Prior ArtReduced glutathione (GSH) is a tripeptide consisting of glutamic acid, cysteine and glycine, which is present in the human body in both reduced and oxidized forms and can be freely converted between the two forms. Among them, reduced glutathione has a stronger antioxidant capacity and higher activity. Glutathione effectively regulates the levels of vitamin C and vitamin E in the body and thus plays an important role in maintaining skin health and retarding the aging process. Ceramide is a lipid present in the horny layer of the skin. It not only prevents moisture loss of the skin and counteracts skin aging, but also forms a barrier on the skin surface, which reduces the penetration of external irritants and the risk of allergic reactions. In other words, a lack of glutathione and / or ceramide in the human body may lead to the acceleration of the process of skin aging.As age increases or due to other environmental factors, glutathione and ceramide content in the human body decreases. In order to replenish glutathione and ceramide content in the human body, there are many functional foods or food supplements on the market which use glutathione and / or ceramide as main components. Glutathione, however, is a peptide which, after entry into the human body, is easily hydrolyzed into amino acids by digestive enzymes and thereby loses its antioxidant effect. Ceramide is a fat soluble molecule. Although it cannot be easily degraded by digestive enzymes, it is difficult for the human body without a fat-soluble carrier to incorporate it.Object of the InventionThe main object of the present invention is to provide a reduced glutathione and ceramide coated with polyphenols in which the sheet-like coating structure prevents the reduced glutathione from being directly hydrolyzed by digestive enzymes, so that the reduced glutathione structurally intact enters the human body and can be absorbed and utilized there to achieve the advantageous effects of an anti-aging effect and a maintenance of the skin condition.It is another object of the present invention to provide a composition of reduced glutathione and ceramide enveloped with polyphenols, wherein the ceramide is enveloped by an envelope layer of fat soluble material to achieve the advantageous effects of accelerating the absorption and utilization of ceramide by the human body and improving the acceptance of taste.To achieve the above objects, the present invention provides a composition of reduced glutathione and ceramide enveloped with polyphenols, comprising a main body and an enveloping layer, the main body containing reduced glutathione and ceramide, the enveloping layer enveloping the main body.The ceramide is extracted from a plant.Here, the reduced glutathione may be derived from a plant or an animal or produced by a microbial fermentation technology and / or an enzyme catalysis technology.For example, in microbial fermentation technology, beer yeast is used to carry out a fermentation process.The composition of reduced glutathione and ceramide coated with polyphenols according to another embodiment of the present invention further comprises a first coating layer and a second coating layer, wherein the first coating layer consists of at least one polyphenol material and is disposed on the surface of the main body and the second coating layer consists of at least one fat soluble material and is disposed outside the first coating layer.In this case, the second enclosing layer is designed as a soft capsule.Here, the first coating layer further comprises an encapsulating material such as maltodextrin, gum arabic, gelatin or silicon dioxide.Brief Description of the DrawingsFIG. 1 is a schematic perspective view of an embodiment of the composition of the invention of reduced glutathione and ceramide enveloped with polyphenols; FIG. 2 is a schematic cross-sectional view taken along section line 2- 2 of FIG. 1.DETAILED DESCRIPTION OF THE EMBODIMENTThe present invention discloses a composition of reduced glutathione and ceramide enveloped with polyphenols, wherein the active ingredients such as reduced glutathione and ceramide are enveloped by at least one enveloping layer in the main body. Not only is this preventing these active ingredients from being destroyed by gastric acid or bile salts, but there can be obtained advantageous effects that the absorption and utilization rate of these active ingredients by the human body is increased, the acceptance of taste is improved, and unpleasant odors are reduced.For better understanding of the technical features and advantageous effects of the present invention, a preferred embodiment will be described in detail with reference to the accompanying drawings.Reference is made to FIGS. 1 and 2. One embodiment of the present invention provides a composition of reduced glutathione and ceramide enveloped with polyphenols 10 comprising primarily a main body 20, a first enveloping layer 30 and a second enveloping layer 40.Here, the main body 20 contains active ingredients such as reduced glutathione and ceramide, which have anti-aging, antioxidant, anti-inflammatory and / or antiallergic effects and can contribute to the increase of skin moisture and to the deceleration of skin aging.Specifically, the ceramide originates from a plant extract, for example from a rice bran extract or wheat germ extract. The reduced glutathione may be derived from foods such as garlic, onions, green tea, grapes, eggs, seafood, etc., or may be produced by biosynthesis technology, chemical synthesis technology or yeast fermentation technology, for example, by fermentation with beer yeast or other microorganisms suitable for food fermentation. Alternatively, a combination of yeast fermentation technology and enzyme catalysis technology may be used to improve the purity and stability of the reduced glutathione.The first encapsulating layer 30 is composed primarily of a polyphenol material and an encapsulating material and encapsulates the surface of the main body 20, the polyphenol material being derived from a plant and having a high antioxidant effect and the encapsulating material acting against digestive enzymes and may be, for example, maltodextrin, arabic gum, gelatin or silica.The second coating layer 40 is designed as a soft capsule made of fat-soluble material and coats the first coating layer 30, wherein the fat-soluble material is phospholipids, medium-chain triglycerides (MKT), polymers or triglycerides.By the composition of the above components, in the composition of reduced glutathione and ceramide enveloped with polyphenols according to the present invention, the main body 20 can be enveloped by the multilayer enclosing structure formed by the first enveloping layer 30 and the second enveloping layer 40. Not only are unpleasant odors thereby masked and the acceptance of taste is improved, but also the direct contact of the main body 20 and the active ingredients contained therein with digestive enzymes of gastric acid or bile salts is prevented, so that the risk of decomposition or inactivation of the active ingredients such as reduced glutathione or ceramide is reduced and the absorption and utilization rate of the active ingredients is increased.Since the first coating layer is made of polyphenol material, it not only provides a sealing effect but also improves the overall antioxidant effect of the composition. Since the second coating layer 30 is made of fat-soluble material, the second coating layer can maintain the activity of the active agents while increasing the absorption rate of ceramide by the human body.From the above description, it is clear that with the composition of reduced glutathione and ceramide enveloped with polyphenols according to the present invention, the disadvantages of the prior art such as inactivation or degradation of the active ingredients and the low utilization rate by the human body are effectively eliminated, thereby enhancing the marketability of consumers and enhancing the effectiveness of the product.The present invention discloses a composition of reduced glutathione and ceramide enveloped with polyphenols comprising a main body and at least one enveloping layer. More specifically, in the present invention, the coating layers coat the surface of the main body in a stacked manner to prevent the main body and the components contained therein from being destroyed by gastric acid or bile salts, and thus attain advantageous effects of increasing the absorption and utilization rate by the human body, improving the acceptance of taste, and reducing unpleasant odors.

Claims

A composition of reduced glutathione and ceramide coated with polyphenols (10) comprising: a main body (20) containing reduced glutathione and ceramide; a first coating layer (30) made of at least one polyphenol material and coating the surface of the main body (20).The composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 1, wherein it further comprises a second enveloping layer (40) made of at least one fat soluble material and enveloping the first enveloping layer (30).Composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 2, wherein the second enveloping layer (40) is formed as a soft capsule.The composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 1, wherein said ceramide is from a plant.The composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 1, wherein the reduced glutathione is produced by a fermentation process using microorganisms.Composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 5, wherein the microorganisms are beer yeast.The composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 5, wherein the reduced glutathione is produced by a microorganism fermentation process and an enzyme catalysis process.The composition of reduced glutathione and ceramide enveloped with polyphenols (10) of claim 1, wherein the first enveloping layer (30) further comprises an encapsulating material.Composition of reduced glutathione and ceramide enveloped with polyphenols (10) according to claim 8, wherein the encapsulating material is maltodextrin, gum arabic, gelatin or silica.