SULCUS PROTEINS FOR THE DETECTION OF PERI-IMPLANTITIS
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- ALBERT LUDWIGS UNIV FREIBURG
- Filing Date
- 2022-06-15
- Publication Date
- 2026-06-10
AI Technical Summary
Current methods for diagnosing peri-implantitis lack non-invasive, reliable, and specific diagnostic tools, with existing tools only indicating disease progression after it has occurred, and there is a limited understanding of the underlying molecular biology, leading to high recurrence rates in treatments.
A method for detecting peri-implantitis by quantifying specific proteins in sulcus fluid samples, comparing them to healthy implants and teeth, using a combination of secreted and shedded proteins, and employing techniques like ELISA, mass spectrometry, and proteomics to identify markers such as IGHV70D and others, allowing for early detection and monitoring of the disease.
Enables early, non-invasive detection and monitoring of peri-implantitis through a specific protein signature, facilitating personalized prevention and treatment strategies by identifying compounds effective against the disease.