Gas sample selector

Abstract

To provide a gas sample selector with reduced sample carryover, in a gas analyzer system.SOLUTION: A gas sample selector 102 comprises a multi-position selector valve 130, a flush valve 140 and a purge valve 150 that are connected to gas sample containers 101, 108. The flush valve 140 is switched to connect an outlet of the flush valve 140, and purge gas flows from a purge valve port 153 through the purge valve 150. The purge gas flows to an outlet 190 of the gas sample selector 102 and a vent port 143 of the flush valve 140, to remove sample gas from a flow path and reduce sample carryover.SELECTED DRAWING: Figure 1A

Description

[Technical field]

[0001] [CROSS REFERENCE TO RELATED APPLICATIONS] none.

[0002] This disclosure generally relates to a gas sample selector for a gas analyzer and and a gas sample selector to reduce sample carryover. Regarding how to make it work. [Background technology]

[0003] Gas chromatograph (GC) is a method to measure the composition of a sample. nt) to produce a signal indicative of the relative amount and / or identity of the analyte in the sample. A gas sample can be analyzed by creating a known and / or repeatable A volume of sample is injected or inserted into the flow path, and the sample is coupled to a stationary phase that separates the analytes. A GC column containing and generate a signal indicative of the relative amount and / or identity of the analyte in the sample. The sample exits through a detector. The carrier gas moves the sample through the GC flow path. Typical carrier gases used in gas chromatography are helium, hydrogen, nitrogen, and and mixtures of argon and methane.

[0004] The samples to be analyzed by the gas chromatograph are placed in various types of containers. For example, samples are sometimes stored in pressurized gas cylinders (typically , 10 psig to 400 psig) or in a sample bag (typically 0 psig to The gas sample selector is used for GC analysis. To facilitate switching between multiple samples introduced into the flow path of the gas chromatograph, Existing gas sample selectors have typically been used with gas column chromatography. A selector inlet is connectable to the container. The selector inlet includes a plurality of a gas sample selector having a plurality of valve inlets for the samples; Multiple positions are used to inject repeatable and / or known volumes of sample into the flow path. The selector valve feeds the sample loop attached to a 6-port 2-way valve in the GC. The sample loop is typically of precise length. and / or tubing of known volume with a diameter. Typical volumes range from 0.025ml to 10ml. Contained in high pressure gas cylinders While filling the sample loop with the sample to be sampled, the sample loop At one end, the outlet of a multi-position selector valve is The restrictor is attached to the sample loop and vented to the atmosphere at the outlet of the sample loop. Typically, the sample is pumped from a high pressure cylinder to allow repeatable filling of the sample loop. A multi-stream selection valve was used to reduce the flow rate of the incoming gas sample. The sample loop is placed between the sample loop and the low pressure gas bag. In the case of existing gas sample selectors, the gas bag is at a lower pressure than the cylinder. Since it is unnecessary to reduce the flow rate of the samples from the multi-position selector valve and the sample There is typically no restriction in the gas sample selector flow path between the (There is a smaller restrictor than that used for the cylinder.) In addition, the gas bag san In the case of a pull selector, the outlet of the sample loop is attached to a pump, which This acts to draw the low pressure of the sample bag into the sample loop. is needed because 100 µm is not sufficient to reliably and repeatably fill the sample loop. After the sample loop is filled, the six-port two-way valve directs the sample loop through the GC column flow. The carrier gas is then switched to be aligned with the sample loop for analysis. The sample contained in the pump is forced onto the GC column.

[0005] The requirements for filling the sample loop are different (i.e., flow from a high-pressure gas cylinder). A restrictor to reduce leakage, versus a pump drawing a sample from a low pressure gas bag, Bags and gas cylinders cannot be analyzed on the same GC system, and gas samples Users who wish to use bags and gas sample cylinders may use two separate systems. It is necessary to use and maintain the

[0006] One item that can cause problems in gas chromatographic analysis is the carryover, i.e., the fraction of a sample that These analytes are then passed through the detector during the subsequent analysis. The peaks, noise, and / or may appear as an elevated baseline.

[0007] Sample carryover contamination in the gas sample selector is prevented by sample loading, Selector switching, or a technique for reducing sample injection, is used to remove old samples from a given portion of the flow path. This involves using the next sample to wash out the residue, which may affect the accuracy of the analysis. One solution to reduce sample loading carryover contamination is to use gas sam- ples. The first step was to use a flush valve in the pull selector. In the pull selector, a filter is used to reduce carryover from one sample to the next. To achieve this, the flush valve position is the same as that of the multiple position selector valve and the 6-port 2-way gas sampling valve. When switching between samples using a multi-position selector valve, The flush valve, which is the on / off valve, is open, and the next part of the sample is taken through the flush valve and the sump. The sample is then drawn through the sample loop flow path and out of the flow path between the selector valve and the sample loop outlet. Any previous sample remaining in the flow channel is pushed out. The new sample pushes the previous sample out of the flow channel. Long flushing times are required to purge from the previous The sample will diffuse back into the new sample in response to any pressure difference between the samples. The time to purge and the amount of residual The amount of sample that flows depends on the volume of the flow channel and the pressure of the gas. Using the sample to extract the sample would waste the sample and This requires that a large number of samples be collected.

[0008] Additionally, the flush valve displaces the sample container connected to the gas sample selector. Used when connecting the gas source to the selector inlet (male-female quick connector After mounting the device using a quick connector, etc., the enclosed contaminating gas is discharged. To do this, the flush valve is opened to flush the sample for a few seconds and then the flush The flush valve is then closed again. This process is manual and inconvenient, and the user must It may be possible to forget to close the valve, which could result in the loss of a sample for further analysis. Drop. Summary of the Invention [Problem to be solved by the invention]

[0009] In one aspect of the present invention, a novel gas sample selector is provided. Novel method for reducing carryover in gas sample selectors for gas analyzer systems - Patents.com is provided. [Means for solving the problem]

[0010] These and other features and advantages of the present apparatus and methods are set forth in the accompanying claims. The scope of the present invention will become apparent from the detailed description below. [Brief description of the drawings]

[0011] [Figure 1A] FIG. 1 illustrates one embodiment of the present gas sample selector for multiple high pressure gas samples. [Figure 1B] FIG. 1 illustrates one embodiment of the present gas sample selector for multiple high pressure gas samples. [Figure 1C] FIG. 1 illustrates one embodiment of the present gas sample selector for multiple high pressure gas samples. [Diagram 2] FIG. 1 illustrates one embodiment of the present gas sample selector for multiple low pressure gas samples. [Figure 3A]FIG. 1 illustrates one embodiment of the present gas sample selector that switches between multiple high pressure gas samples and multiple low pressure gas samples. [Figure 3B] FIG. 1 illustrates one embodiment of the present gas sample selector that switches between multiple high pressure gas samples and multiple low pressure gas samples. [Figure 4] 1 is an exemplary workflow for reducing carryover in a gas sample selector. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0012] In the accompanying drawings, solid and dotted lines are generally used to illustrate the various flow paths available within the device. For some operations described herein, solid lines represent the flow paths through which A dashed line is used to indicate that gas is flowing or the flow path is open, while a dotted line indicates that gas is The dotted line indicates that no gas is flowing or the flow path is blocked. It should be recognized that the different structures do not necessarily represent different

[0013] The features illustrated in the drawings are not necessarily drawn to scale. The following detailed description is best understood when read in conjunction with the following:

[0014] In view of the present disclosure, devices and methods can be implemented in light of the present teachings. It is noted further that the various components, materials, structures, and parameters are merely examples. It is intended that the present teachings be incorporated herein by reference in their entirety and are included as illustrative and exemplary embodiments, and not limiting. Components, materials, structures, and methods that may be implemented in applications and that implement these applications; Various devices may be determined while remaining within the scope of the appended claims.

[0015] 1A, 1B, and 1C show the gas sampler as part of a gas analyzer system 100. 1 illustrates an embodiment of a gas sample selector (GSS) 102. The selector 102 includes a multi-position selector valve 130, a flash A flow path is provided between the valve 140 and the purge valve 150. 1A, 1B, and 1C show a gas sample being fed to a gas chromatograph. 104 followed by purging the gas sample selector conduit; This will allow you to determine how to use the gas sample selector to reduce carryover contamination. The multi-position selector valve 130 is fluidly connected to a purge valve 150. The flush valve 140 is fluidly connected to a flush valve 140 that is connected to the Thus, the term "fluidically connected" is used herein to mean When used, two components are in fluid communication, including direct and indirect connections. This means that

[0016] More specifically, the gas sample selector 102 selects one or more gas sample containers. The container is connected to a high-pressure sample container (e.g., container 101, 108). As used herein, the term "gas sample" refers to a gas sample that is capable of being stored in a gas storage tank. The term "high-pressure" as used herein refers to pressure applied from a pump or by another source. The gas must flow through the gas sample selector flow path without assistance from applied pressure or the like. In some embodiments, high pressure refers to sufficient pressure to The pressure is sufficient to produce a flow rate of 10 ml / min to 300 ml / min through the passage. High pressure gas samples generally have pressures in the range of 10 psig to 400 psig. The container has a shutoff valve (e.g., shutoff valve 111) attached to the outlet of the container. and the shutoff valve is opened after the sample container is attached to the gas sample selector. Release the shutoff valve 11 to allow the gas sample to exit the container. 1 is opened and a gas sample from the container 101 is fed into the sample of the gas chromatograph 104. Shut off valves for other containers. The shutoff valve (e.g., shutoff valve 118 for container 108) is also opened to allow gas to escape from other containers. A gas sample is introduced into the sample selector 102, more specifically into the inlet of the multi-position selector valve 130. The gas sample selector 102 is a multiple of a plurality of gas sample receiving means. The gas sample selector 102 includes a selector inlet (e.g., selector inlet 121). Multiple selections are made to select which gas samples will flow through the GSS to the gas chromatograph 104. A multi-position selector valve 130 is also provided. The selector inlet may be a quick connector or a conduit for fluid flow. a gas sample connector, such as a gas sample selector, or other fitting suitable for connecting In some embodiments, the mating connector may include a connector that is attached to the A gas sample connector is used, the gas sample connector has a male connector, and the selector inlet has a female connector. When the connectors are physically mated, the female connector When the connector is opened and the connector is removed, the female connector closes. In this case, the sample container can be connected directly to the selector valve, in which case the selector inlet The port is a selector valve inlet on the selector valve 130. In some embodiments, the selector valve is a rotary valve, the rotary valve having a plurality of selector valve inlets and at least one selector valve inlet in a stator. One selector valve outlet and a cutout which may be a groove or channel in the rotor. The fluid path can be switched by rotating the stator and / or rotor. The selector valve inlets are connected to at least one selector valve outlet. The selector valve 130 connects to a plurality of selector valve inlets (e.g., selector valve inlets 131, 1 32) and at least one selector valve outlet 133. In FIG. The gas sample from 01 enters the gas sample selector through selector inlet 121 and The loading conduit 123 leads to the selector valve inlet 131. Optionally, as in some embodiments, the selector inlet may be a selector valve inlet. The selector valve 130 allows the gas sample to flow to the selector valve outlet 133 and Positioned so that gas samples from container 108 (and any other containers) are blocked. As the selector valve 130 moves to different positions, different selector valve inlets 132 The valve outlet 133 is fluidly connected to the valve outlet 133. In some embodiments, the multi-position selector valve is For example, the selector valve inlet is not fluidly connected to the selector valve outlet, such as to provide a closed valve position. In some embodiments, the selector 102 may have multiple loads. The device also includes a loading conduit (e.g., loading conduits 123, 124). The selector inlet is connected to the selector valve inlet. An exemplary loading conduit is stainless steel or This includes tubing made of other inert materials.

[0017] The selected gas sample is passed from the selector valve outlet 133 to the selector-flush conduit. a flush conduit 139 at its other end fluidly connected to a flush valve 140; The selector-flush conduit 139 is connected to the flush valve 140. In one of the positions (the position shown in FIG. 1A), The flush valve 140 is disposed between the flush valve inlet 141 and the flush valve outlet 142. A flow path is provided for the gas sample to pass through the flush-purge conduit 149 to the purge valve 15. It makes it possible to reach 0.

[0018] The flush valve 140 has a flow path between a flush valve inlet 141 and a flush valve outlet 142. and in the second valve position, flush valve outlet 142 and flush valve vent port 143 are connected to each other. The valve may be a two-way valve capable of providing a flow path between the port 143 and the In the embodiment, the flush valve inlet 141, the flush valve vent port 143 and the flush valve outlet 142. In some embodiments, the flush valve is a three-way valve. 2. It provides minimal dead volume for trapped gases, allowing high pressure operation; It may be a 4, 6, or 10 port rotary valve, or in other embodiments, a flow valve. The flush valve can be a solenoid valve. The flush valve vent port 143 is in the surrounding area around the sample selector 102 (e.g., a room, a lab hood, etc.), or The exhaust gas may be discharged into a gas container for collection. The flush valve vent port 143 may be fluidly connected to a flow restrictor 144. A volume restrictor is a specified device used to restrict flow through the flush valve vent port. The valve may be a needle valve or tubing with an adjustable inner diameter and length.

[0019] In another embodiment (not shown), the flush valve is a two-port valve having an on / off position. In the "on" position, the flush valve inlet and the flush valve outlet are fluidly connected In the off position, the two are not fluidly connected.

[0020] The purge valve 150 has at least two purge valve positions. In the purge valve position (the position shown in FIG. 1A), the purge valve 150 has a purge valve inlet 151. and the purge valve outlet 152 without connecting either to a purge gas source. The gas sample exits the purge valve outlet 152 and flows into a purge-outlet conduit 154. Examples of suitable valves for the purge valve 150 include flow switching valves. Other examples include three A set of tees connecting the purge valve ports and shutoff valves attached to the purge valve outlets This includes the combination of larger volumes of sample in the flow path where the sample may become trapped. An alternative is to introduce purge gas into different volumes of the GSS at different purge valve positions. For example, a 3-port 2-way or 3-way valve that allows sample gas to flow through the sample In one purge valve position, such as for loading a pool, the purge valve inlet and outlet are in fluid communication. The purge valve position can then be switched to another position and the purge gas is a purge valve outlet for purging the flow path after the purge valve (e.g., a downstream portion of the GSS); The purge valve position is then switched again, the purge gas and the inlet are fluidly connected, and the purge valve Purge the flow path between the high pressure sample and the flush valve (e.g., the upstream portion of the GSS). In this case, the purge-exit conduit 154 is a repeatable To facilitate efficient and reliable filling, the sample gas is drawn from the sample container through a flow path. A flow restrictor (not shown) sized to restrict the flow of It is also contemplated that the flow restrictor may be can be set up to limit flow based on the pressure of an attached sample container In another embodiment, the flow restrictor is a known adjustable needle valve. During filling of the sample loop, the restrictor may be a fixed restrictor such as a tube of an inner diameter and length of 1. Typical sample flow rates can range from 10 mL / min to 300 mL / min.

[0021] The selector 102 also includes a selector outlet 190 through which the gas sanitation The extractor 102 is passed through a gas chromatograph 104, more specifically, a gas chromatograph 105. 1A, the purge-outlet conduit 154 The selector outlet 190 is connected to the purge valve outlet 152, and the selector outlet 190 may be one or more. or may be indirectly fluidly connected to the purge valve 150 via another component of the If a flow restrictor is not included in the purge-outlet conduit, the purge valve outlet 152 is the selector. It is contemplated that the purge valve 150 may also serve as an outlet 190. In FIG. 1A, the purge valve is connected to a sample gas source of the gas chromatograph. Ensure that the purge gas is shut off from the gas selector while loading the sample into the pull loop. It will be closed down.

[0022] FIG. 1A illustrates the process of filling a sample loop with sample from a selected gas sample container. In most gas chromatographs, the sample loop is The sample loop is filled with a filter, and then a fluid connection is made to transfer the gas sample from the sample loop to the GC column. The selected sample is switched for loading into the connected sample controller. From the retainer, through the multi-position selector valve 130, through the flush valve 140 and the purge valve 150. The gas flows into a gas sampling valve 193 in the gas chromatograph 104, where it is sampled. The sample flows through one or more sample loops or channels, such as sample loop 191, Fill the sample loop with sample gas. When the sample loop is filled, The outlet of the sample can be vented to the atmosphere in this configuration where the sample is a high pressure gas cylinder. The time to fill the sample loop is based on the gas flow rate and the volume of the sample loop. The sample loop is a 2-port 6-way sampling valve or a selector flow path shown in Figure 1A or G C Attach to another valve that allows the sample loop to be aligned with the column flow path. However, more or less than six ports and more or less than two ports can be used. One or more sampling valves having different positions, as well as other structures including one or more sample loops. In some embodiments, the sample loop is filled with the gas sample. After the sample loop is placed in fluid connection with the GC column 195, The flush valve 140 is adapted to fluidly connect the flush valve outlet to the flush valve vent port. As the sample loop 191 is switched in this way, the pressure in the sample loop 191 is allowed to equilibrate with the surrounding area. This pressure equilibration step can be carried out for between about 3 seconds and about 10 seconds. After the sample loop 191 is fully filled with sample, a six-port two-way gas sump is inserted. Ring valve 193 is switched to a second position (not shown) to allow carrier flow from port 194. The agarose is then passed through the sample loop onto the GC column 195 and into the sample gas. The sample is then pumped through a detector 196 which detects the analyte in the sample. A typical sample flow rate is When the loop is filled, the flow rate ranges from 10 ml / min to 300 ml / min and moves through the GC column. When this occurs, the flow rate ranges from 2ml / min to 40ml / min.

[0023] FIG. 1B illustrates a gas sample from a portion of the conduit of the gas sample selector 102, and optionally Generally, it may be desirable to purge the gas chromatograph 104, and in particular the sample loop 191. 1 shows the operation of the gas sample selector 102 when the gas sample is being extracted from the container 101. After the gas sample has flowed, the positions of the purge valve 150 and flush valve 140 are changed to allow for the remaining sample to flow. Pulse gas (i.e., gas sample that was not loaded into the GC flow path, including the column) The flow path including the sample loop 191 is switched to be removed, and carryover is prevented. The purge valve 150 is adapted to receive purge gas from a purge valve port 153. When the flush valve 140 is open, the flush valve outlet 142 and the purge valve vent port 14 3. In another embodiment, the two-way flash The flush valve is switched to the off position. The flush valve is switched to the off position either simultaneously or before the purge valve opens. The purge valve 150 and / or flush valve 140 can be switched manually or In this purge valve position, the purge valve 15 can be switched automatically (preferably). 0 is a purge valve that allows purge gas to flow to the purge valve inlet 151 and the purge valve outlet 152. Allows flow of purge gas from valve port 153. Flush valve is in the off position. In another embodiment, which is a two-way valve, purge valve 150 directs purge from purge valve port 153. 1. The purge valve 152 may be switched to a position that allows the flow of purge gas to the purge valve outlet 152. The purge valve port 153 is filled with a chemically inert gas (e.g., nitrogen, argon, or helium). In some embodiments, the purge gas is connected to a source of purge gas, such as air. The gas is the same type of gas used as a carrier gas for GC. In operation, purge gas flows into purge outlet conduit 154 and into the residual gas downstream of the purge valve. Removes sample gas and prevents carryover. Restrictors, which can be adjustable or fixed However, the purge gas is used to limit the total flow rate of purge gas into the gas sample selector. A valve port 153 can be fluidly connected to the valve port 153. A typical purge flow rate is 100 mL / min to The gas sampling valve 193 in the GC 104 can be set to 1000 mL / min. A sample loop 191 defines a flow path of gas exiting the gas sample selector through the selector outlet 190. 19 to allow the sample loop 191 to be purged. The purge gas then exits the chromatograph exit 198 into the environment. or in some embodiments, the purge gas flows to the selector return port 192 back to the gas sample selector 102. In the flush-purge conduit 149, the purge gas also passes through the flush valve vent 148. Flows out of port 143 to remove any remaining sample gas downstream of the flush valve Flow Restrictor 1 prevents carry-over contamination from residual sample gas. 44 is provided to control the flow rate of the purge gas discharged to the atmosphere. Exemplary flow rates for include about 100 mL / min to about 1000 mL / min. In some embodiments, the purge time is from about 0.1 minutes to about 5 minutes. The time during which the gas sample is analyzed in the gas analyzer 104 is substantially the same as the time during which the gas sample is analyzed in the gas analyzer 104. The time depends on the volume of the flow path, the type of sample, and the flow rate of the purge gas. 44 is a flow path downstream of the purge valve, including a conduit, a sample loop, and / or a sampling The flow of purge flow is restricted between the flow path having an inherent restriction based on the purge valve and the flow path upstream of the purge valve. The amount of restriction is between the purge valve and the sample loop outlet. The flow rate of purge gas through the inlet and outlet of the purge valve is specified based on existing limitations between This balances the flow rates and allows the flow paths upstream and downstream of the purge valve to be sufficiently swept. The flow restrictor may be a needle valve, a piece of tubing having a specified inner diameter and length, or a flow restrictor for restricting the flow rate of a fluid. The present invention may be implemented as a device capable of reducing the

[0024] FIG. 1C shows the flow of gas from a further conduit of the gas sample selector 102, i.e., from the flush valve 1 When it is desired to purge the gas sample upstream of 40, the gas sample selector 10 1C illustrates the operation of the gas sample selector 102. The flush valve 140 is connected to a flush valve inlet 141 and a flush valve outlet 142. The selector valve 130 (outlet 133 and inlet 142) is switched to a fluidly connected position. 31), a loading conduit 123, and a purge valve 15 through the selector inlet 121. 0. Optionally, the user may select If the selector inlet does not open automatically, open the selector inlet by selecting the reciprocal connector. It can be opened intentionally, such as by inserting it into the selector inlet. The purge gas introduced by 153 is fed through the loading conduit 123, the selector-flush A sample is drawn from one or more of the conduit 139, the multi-position selector valve 130, and the selector inlet 121. In some embodiments, some or all of the gas sample container is , the gas sample selector 102 and the selector valve 130 is switched so that the remaining sample is not The part may be switched between predetermined positions to be removed from some or all of the feeding conduit. The gas also passes through purge outlet conduit 154 and exits selector outlet 190 to be mixed with the gas quencher. The purge gas flows into the chromatograph where it flows through a sample loop 191. In this procedure, which can be called sweeping, the residual sample is A flow path including the sample selector 102 and the sample loop 191 in the gas chromatograph 104. from the aliquot, thereby preventing or reducing carryover.

[0025] In the systems shown in FIGS. 1A, 1B, and 1C, a gas cylinder (or additional auxiliary A container with sufficient internal pressure to fill the sample loop without assistance is placed in the selector inlet 1. The present disclosure also provides a method for switching between different gas sample containers. To provide an automated method for determining the concentration of each of the different gas samples, The gas sample selector 102 can provide the gas sample to the rough 104 efficiently and reliably. External devices (gas chromatographs, computers with RS-232, or other types) When a new sample arrives, such as a new sample position signal from a gas analyzer in a Upon receiving a signal indicating that the sample is to be sampled and analyzed, the multi-position selector valve 130 selects a different sample. The pull containers are switched to different positions corresponding to the pull containers. The flush valve 140 fluidly connects the flush valve inlet 141 and the flush valve outlet 142. In order to open the valve, a dead space between the port of the multi-position selector valve 130 and the flush valve 140 is provided. The previous sample sealed inside the volume is expelled and then filled with the new sample. After a short time, the flush valve 140 closes again (i.e., flushes The flush valve inlet 141 is not fluidly connected to the flush valve outlet 142 so that the new sample The gas sample selector 102 holds the sample. This mechanism is triggered by selector switching. Minimize carryover contamination caused.

[0026] FIG. 2 illustrates a configuration for multiple low pressure gas samples (e.g., gas bags 201, 208). 1 illustrates one embodiment of the present gas sample selector. The term "low-pressure" refers to the flow path of the gas sample selector at the desired flow rate without assistance. In some embodiments, the desired pressure is insufficient to allow gas to flow through the The flow rate of the gas may be 10 mL / min to 300 mL / min. Pressure applied by a pump or another source to cause fluid to flow through a flow path at a certain rate For example, a pressure of about 0 psig to 10 psig may be required. The gas samples to be analyzed will require assistance. The valve states shown in Figure 2 are C. Configure the flow path to fill the sample loop with the sample that will be inserted later into the flow path. The sample selector 202 includes a multi-position selector valve 230, a flush valve 240, and a purge valve 242. A valve 250 and conduits 239, 249 provide a flow path therebetween. The pull selector 202 is part of the gas analyzer system 200 and is connected to the gas chromatograph 20 4, and a plurality of gas bags (e.g., 201, 208) for containing low pressure gas samples. The container is fluidly connected to another container that is connected to the outlet of the container. The container may include a valve, the shutoff valve being adapted to allow the gas sample to exit the container. The sample is attached to the gas sample selector and then released. The sample enters the selector valve inlet 23 through the selector inlet 221 and the loading conduit 223. 1. The multi-position selector valve 230 has a selector valve inlet 231 connected to a selector valve outlet 23 3, and the gas sample from the container 208 (and any other container) is The selector valve 230 is in the cut-off position to select different gas samples for analysis. Alternatively, the selector valve may be moved to a different position (eg, the selector valve inlet 232).

[0027] The selected gas sample is passed from the selector valve outlet 233 to the selector-flush conduit 239 a selector-flush conduit, the selector-flush conduit being fluidly connected at its other end to a flush valve 240. In the flush valve position shown in FIG. a flow path between the flush valve inlet 241 and the flush valve outlet 242, Allows air to pass through rush-purge conduit 249 to purge valve 250. Valve 250 provides a flow path between a purge valve inlet 251 and a purge valve outlet 252. The valve 253 is closed to the flow of purge gas into the system. The gas flows out of the purge valve outlet 252 into the purge-outlet conduit 254 and into the purge-outlet The conduit 254 is fluidly connected at its other end to a selector outlet 290 (although the selector outlet 290 is indirectly fluidly connected to the purge valve 250 through one or more components. (It is intended that this will be possible.)

[0028] The embodiment of the present gas sample selector shown in FIG. 2 is configured for multiple low pressure gas samples. In this embodiment, the gas sample selector 202 selects the gas sample pump 28. 2, and optionally positioned downstream of the sample loop during filling of the sample loop. A pump valve 280 is attached to the outlet of the GC gas sampling valve. Examples of sample pumps include diaphragm pumps and vacuum pumps. The pump 282 pumps the low pressure gas sample to atmosphere without any motive force. Therefore, the pump valve 28 is provided to prevent the pull loop from filling properly. 2. Pump the gas sample through the flow path containing the sample loop to the vent 281 282 It has a position that can be extracted by

[0029] The pump 282 is fluidly connected to the conduits of the gas sample selector 202, thereby selecting the gas sample. and optionally, to draw the gas out of the gas chromatograph. In FIG. 2, the pump is connected to the selector outlet 290, the gas chromatograph 204, The sample loop 291, the selector return port 292, and the return-valve conduit 257 are The gas chromatograph 204 is fluidly connected to a flow path including a gas sampling valve 293. The gas sampling valve 293 is configured to allow the sample gas to flow from the sample loop to the GC column 29 5, and the sample gas flows through the sample loop and / or into the sample It can be switched between multiple positions, such as a position where the loop is filled and the excess is discharged. The gas chromatograph 204 uses a capillary to push the sample gas through the GC column. A carrier gas port 294 for receiving a rear gas and a gas detector port 295 for detecting analytes in the sample gas. The selector return port 292 may also include a detector 296 that is connected to the sample loop 2. 91 to fill the sample loop or purge the flow path. Allows return of gas samples from the chromatograph 204 to the gas sample selector 202 A return-valve conduit 257 connects the selector return port 292 to the pump valve 280. To be continued.

[0030] The flush valve 240 and purge valve 250 of FIG. To purge the sample gas from the sample loop 291, a flush valve 140 and a purge valve The valve 150 operates in substantially the same manner as described above in FIGS. 1B and 1C. However, in embodiments where a low pressure sample gas is used, During purging, valve 280 is switched to vent 283 because the purge gas is generally at a higher pressure than the sample gas, so pump 282 is not required. .

[0031] 3A and 3B show a gas chromatograph 304 and 16 gas sample containers. One of the gas sample selectors 302 as part of a gas sample analyzer system 300 including 3 illustrates an embodiment of a gas sample selector 302 that selects a plurality of gas samples (e.g., 301 and gas cylinder 316). It has 1 bag and 8 cylinders, 4 of which are visible. This is a low pressure san The gas sample selector can accept both pull and high pressure samples, It has advantages over other gas sample selectors.

[0032] The selector 302 includes a plurality of selector streams that receive gas samples from a plurality of sample containers. The selector 302 also includes a plurality of selector valve inlets. A multi-position selector valve having an inlet (e.g., inlet 331) and at least one selector valve outlet 333. The selector valve 330 has a selector valve inlet 331 connected to a selector valve outlet 333. In FIG. 3A and FIG. 3B, the multi-position selector valve is in a position to be fluidly connected. Although shown with a selector valve inlet (as discussed above), the selector valve may have more or For example, a multi-position selector valve may have 2, 3, 4 inlets. , 6, 8, 10, 12, 20, 24, 32, 36, 40 or more selector valve inlets The multi-position selector valve is also shown with one selector valve outlet 333. However, it is contemplated that the multi-position selector valve can have two or more outlets. The selector 302 also optionally selects a plurality of loading conduits (e.g., Tube 323), the loading conduit connecting the selector inlet to one of the selector valve inlets. The selector inlet to the loading conduit may be fitted with a connector such as a quick connector or hose connector. It may have fittings that facilitate connecting and disconnecting the sample container; Alternatively, the selector inlet may be constructed of materials such as soft plastic or rubber tubing. can be done.

[0033] The selector 302 includes a flush valve 340 having at least two flush valve positions. In the position shown in FIG. 3A, the flush valve 340 has a flush valve inlet 341 and A fluid path is provided between the rush valve outlet 342 and, in some embodiments, another In this embodiment (not shown), the flush valve 340 is connected to a flush valve vent port 343. A fluid path is provided between the lash valve outlet 342. The flush valve can be a three-way valve. The flush valve vent port 343 is The selector 302 may also be fluidly connected to a selector valve outlet 344. A selector-flush conduit 339 is provided which connects to the valve inlet 341 .

[0034] The selector 302 also includes a purge valve 350 having at least two purge valve positions. In one of the purge valve positions, the purge valve 350 has a purge valve inlet 351 and a purge valve outlet 352. 352, providing a closed or two-way flow path between the purge valve 352 and another purge valve position (not shown). In this embodiment, purge valve 350 provides a multi-way flow path or intersection including purge valve port 353. To this end, a purge gas can be provided to the purge valve inlet and the purge valve outlet. The port 353 is fluidly connected to a purge gas source. The rush valve 340 is connected to the purge valve 350. The flush valve 340 and the purge valve 250 Suitable materials and operation of the flash are described above in connection with FIGS. 1A-1C. Although valve 340 and purge valve 350 are advantageous, it is possible to omit the flush and / or purge valves. Various embodiments of the present invention are also capable of switching between sample containers of different pressures. It should be recognized that both are optional in that it is highly advantageous to

[0035] In the embodiment shown in FIG. 3A and FIG. 3B, the gas sample selector 302 also A complex valve 350 having a plurality of ports fluidly connected to the valve 350 and serving as a valve inlet and a valve outlet. In an embodiment without a purge valve, the multi-port valve 360 ​​includes: The flush valve 340 or, if the flush valve 340 is also omitted, the selector valve 33 3A and 3B, the multi-port valve can be fluidly connected to a 10-port In these figures, the solid lines represent open and closed two-way valves, although other valve types are also contemplated. is used to indicate that gas flows through the outlet, while the dotted lines indicate that the flow path is entirely The various valve positions are shown in FIG. 3 as closed. The multi-port valve 360 ​​is Different flow rates are required for the gas sample depending on whether the source is high pressure or low pressure gas. The multi-port valve 360 ​​is configured to provide a path for the selected sample container. Depending on the pressure, the sample gas is directed to different components.

[0036] In FIG. 3A, the multi-port valve 360 ​​is connected to the high pressure gas sample (i.e., the shutoff valve 317 is in position to receive a sample from the gas cylinder 316 when the gas cylinder 316 is open. The valve state shown in A allows high pressure sample to be loaded into the sample loop of the GSS and GC. The gas sample is received at valve port 361, and valve 360 ​​is connected to valve port 362. 62. The gas sample exits valve 360 ​​at a flow rate The gas sample passes through a conduit having a restrictor 370. From here, the gas sample exits the valve port at a reduced pressure. 363, where the gas sample flows through multiple ports that provide a flow path to port 364. The gas sample exits valve 360 ​​and passes through valve-outlet conduit 356. The gas sample is then passed through a gas sampling valve 393 to a selector outlet 390. It flows to the gas chromatograph 304 and into its sample loop 391. In one position of the ring valve 393, the sample loop 391 is connected to the selector return port 392, and the gas sample is passed through return-valve conduit 357 to vent 37 Port 3 of multi-port valve 360 ​​provides a flow path (having one or more conduits) to 65. A flow restrictor 370 fluidly connected to one of the multi-port valve outlets restricts the high pressure gas A needle valve or other design (such as a fixed restrictor in the form of a tube) may be used to restrict the flow of the sample. In some embodiments, the flow restrictor 370 may be configured to between 10 mL / min and 300 mL / min, alternatively between 20 mL / min and 200 mL / min In another position of the gas sampling valve 393, the sample gas is limited to between The sample loop 391 flows to the GC column 395. The gas chromatograph 304 is The sample gas is mixed with the carrier gas to push it through the GC column 395. A carrier gas port 394 for receiving a gas and detecting an analyte in the sample gas. A detector 396 may also be included.

[0037] The multi-port valve 360 ​​allows the selector 302 to select the pump and flow rate in response to the pressure of the gas sample. In FIG. 3B, the selector 120 allows the gas sample to be switched between the restrictor and the flow path of the gas sample. A selector 302 receives a low pressure gas sample from a container 301 (e.g., a gas bag). The gas sample enters the selector inlet 322 and passes through the loading conduit 324. The loading conduit 324 is connected to a valve inlet 332 and a gas selector valve 330. The gas sample valve outlet 333 is fluidly connected to the pull valve outlet 333. 333 is directly fluidly connected to the multi-port valve 360 ​​and provides a flow path between the high pressure sample and the low pressure sample. In another embodiment, the present invention provides the advantage of allowing a user to easily switch between The gas sample selector 302 also provides the added benefit of helping to eliminate carryover contamination. To accommodate this, the flush valve 340 and / or the purge valve 350 are included. In this embodiment, the flush valve 340 and the purge valve 350 are the same as the flush valves 140, 240. and the above-described method of purging the sample gas with the purge valves 150, 250. As mentioned above, the flush valve and / or An embodiment without a purge valve is also advantageous.

[0038] In FIG. 3B, the multi-port valve 360 ​​is configured to allow the low pressure gas sample (i.e., gas bag 3 01). The pump 382 and pump valve 380 are A gas sample pump 380 is fluidly connected to one of the port valve outlets 366. In FIG. 3B, the gas is pumped through a plurality of nozzles. The multi-port valve 360 ​​allows the low pressure gas sample (i.e., the bag) to flow after the shutoff valve 311 opens. The gas sample is received at valve port 361. The valve 360 ​​provides a flow path (through an internal channel) to a valve port 364. The sample exits valve 360 ​​and passes through valve-outlet conduit 356 to selector outlet 390. The gas sample flows to a gas chromatograph 304, which operates as described above. In one position of the sampling valve 393, the sample The loop 391 is fluidly connected to a selector return port 392, and the gas sample is returned to the selector. The multi-port valve 360 ​​is connected to the pump valve 352 via the valve conduit 357 to the port 365. A flow path (e.g., an internal channel) between ports 365 and 366 that is fluidly connected to 380 In one position, pump valve 380 provides a pump 382 and a pump vent 38 1 and in another location, connect port 366 to vent 383. The pump 382 is connected to the valve-outlet conduit 356, the selector outlet 390, and the gas chromatograph 3 04 sample loop 391, selector return port 392 and return-valve conduit 357 The valve state shown in FIG. 3B can provide intake pressure to a flow path comprising Filling the sample loop 391 in the GC 304 with sample gas from the bag 301 This makes it possible.

[0039] The gas sample selector 302 performs the steps discussed in connection with FIGS. 1A, 1B, and 1C. The gas sample selection may be used to reduce carryover. The vessel 302 includes a purge source 350 fluidly connected to a purge gas source, and the purge valve is The purge gas source is selectably controlled to purge the sample selector. A carrier gas source provides the carrier gas, or it can be another gas such as nitrogen or air. During purging, the multiport valve 360 ​​is in the position it was in for the previous gas sample. Any previous residual gas samples can be in the same location as the are removed in an attempt to reduce

[0040] In the apparatus shown in FIGS. 3A and 3B, low pressure gas sample containers 301-308 (e.g., A gas bag (for example) is attached to the selector inlet, and a high-pressure gas sample container 309 316 (e.g., a gas cylinder) is attached to the selector inlet. In the gas sample selector 302, the sample selector 302 selects the sample cone according to the detected sample position. In some embodiments, the selector inlet determines a particular type of Alternatively, the selector inlet may be configured to connect to any type of container. The GSS can be configured to connect to a pressure vessel or other type of container. By having a sensor or container type, the user can identify By providing a user interface, etc., to detect the type of container. The GSS then directs the high pressure sample gas through a flow restrictor 370. or to flow low pressure sample gas through pump 382. Determine appropriate action for cylinder or bag, such as switching 60 position More specifically, one gas sample (gas system) requires a restrictor 370 to limit the flow rate. Another pressure gas sample (gas bubbler, etc.) that requires the assistance of pump 382 is generated from the When the gas sample selector 302 receives a signal to switch to a gas sample selector (e.g., gas sample selector 301), the gas sample selector 302 selects one of multiple positions. The selector valve 330 can be switched to different positions and the flush valve 340 is a multi-position selector. The previous sample inside the dead volume between the port of valve 330 and flush valve 340 is drained. The sample is then released to be washed away by new sample. The flush valve 140 is then closed again. This procedure transfers the high pressure gas sample to the low pressure gas sump. caused by switching from a low pressure gas sample to a high pressure gas sample This minimizes carryover contamination.

[0041] The apparatus (as illustrated by the embodiments described herein) includes a gas sample selection The controller may be part of the gas sample selector or as an external device in communication with the gas sample selector. The controller typically includes a processor and a memory. The controller controls the selector valve, flush valve, purge valve, multi-port valve, pump, and / or or in electrical communication with the pump valve to receive data from and / or issue commands to the pump valve. Send the code.

[0042] FIG. 4 illustrates an exemplary workflow for reducing carryover in a gas sample selector. As a first step, the gas sample container is inserted into the gas sample selector. The gas sample container is then attached to the outlet of the If the engine has a shutoff valve attached, the shutoff valve is opened. The position selector valve is configured to allow the valve inlet port to flow to the valve outlet for the position where the sample container is connected. The flush valve is positioned between the selector inlet and the selector outlet. When removing and reinstalling the sample sealed inside the volume between The gas sample, purge gas, or possibly air, is introduced through the selector outlet or vent. The gas sample is then discharged from the gas sample selector and then filled with a new gas sample. The flush valve inlet is positioned to connect to the flush valve outlet. In those embodiments that include a multi-port valve (such as multi-port valve 360 ​​shown in FIG. 3A), The multi-port valve may be configured to provide a desired flow path (e.g., a flow restrictor or After a preset time, the flow path is switched to a position that provides a flow path with a pump. The flush valve fluidly connects the flush valve vent and the flush valve outlet and / or The flush valve is switched to a position that prevents fluid communication between the flush valve inlet and the flush valve outlet. In some embodiments, the flush valve is automatically switched between valve positions. This procedure minimizes carryover contamination caused by sample loading. A purge gas source is then fluidly connected to the purge valve inlet and the purge valve outlet, The gas flushes the system from the purge valve to the flush valve vent and then to the selector outlet. If the selector outlet is fluidly connected to a GC and a sample loop, the sample loop is also flushed. The selector valve is closed when the flush valve inlet is closed (i.e., the flush valve outlet While the gas sample is being sampled, the gas sample can be sampled at a different position. until all of the gas sample selector valve inlet and the loading conduit are loaded onto the loading conduit and the selector valve inlet of the gas sample selector. In some embodiments, the gas sump in the sample container Some or all of the files may need to be loaded in their respective In some embodiments, one of the gas samples is loaded into a gas conduit. The gas sample is loaded into the loading conduit and the workflow for that gas sample is The gas sample is loaded into each of the loading conduits. Continue (as described below) before downloading.

[0043] Next, in the workflow for a gas sample, a signal (from the controller or A gas sample is provided by the user (e.g., by pressing the "inject" key) and (optionally Typically, after the "load" mode step is performed for the gas sample to be injected, The gas analyzer can be introduced in the "on" mode. The initial state is when the flush valve is The flush valve is in a "standby" position, fluidly connecting the flush valve vent and the flush valve outlet. The GSS receives a signal (from an external device or When the device receives a pre-run start signal from a key pressed by the user, it enters the pre-run state. In that state, the gas passes through the GSS and into the gas analyzer (e.g., into the sample loop). To provide a flow path for the gas sample, the flush valve flushes the flush valve inlet. The gas sample selector is switched to the position that connects the high pressure gas sample and the low pressure gas sample. In some embodiments of the method having the ability to switch between a pressurized gas sample, A multi-port valve is provided to switch from a flow path including a restrictor to a flow path including a pump, or vice versa. A signal is also provided to switch flow paths within the GSS, such as by switching The signal may be provided automatically or manually, and is generally provided by a gas sample container. The pre-operation state is based on the pressure of a specific gas sample provided by the GSS. The pre-run state or flushing time is determined by the user. Typically, the time can be selected from 0.4 minutes to 4 minutes, alternatively, from 0.9 minutes to 1 minute. After that, the system goes into the "Run" state, where it The flush valve is positioned such that the flush valve vent is fluidly connected to the flush valve outlet ( or to a position that prevents fluid communication between the valve inlet and the valve outlet, and the gas analyzer Before the sample is introduced, the sample pressure in the sample loop is equal to that of the surrounding area (typically at atmospheric pressure). A few seconds are given to allow the temperature to reach equilibrium. This operation is considered to have good repeatability. During injection, the sample loop is aligned with the GC column flow path. After a preset time (or In response to the signal, the gas sample selector is in a "PostRun" state. In this state, the gas sampling valve is The loop is placed in fluid communication with the outlet of the gas sample selector and the flush valve is Connect the flush valve vent and flush valve outlet (or connect the flush valve inlet and flush valve outlet). the purge valve is positioned in a position that closes the fluid connection between the flush valve and the selector A gas sample is placed between the outlet of the sample loop in a GC or the pump outlet in a GSS. The purge selector is switched to a position that allows purge gas to flow into the sample flow downstream of the flush valve. The duct is washed for the next sample injection, which means that the next sample will not be washed out of the previous sample. This helps reduce the time required to flush the flow path. If a sample is present, the multi-position selector valve can switch to the next sample position. The process from standby to post-operation is then repeated for the remaining samples. It is possible.

[0044] After all samples were analyzed, the sample flow path was cleaned to remove all sample residues. The sample container can be physically removed by the user from the gas sample selector. The selector inlet can be easily disconnected by simply disconnecting the sample container. If required based on the type of connector used for the inlet or selector, Opening to atmosphere by connecting a fitting to open the selector inlet to atmosphere. The gas sample selector is placed in "Sweep" mode. In the mode, the flush valve is in a position connecting the flush valve inlet to the flush valve outlet. The purge valve is moved to the selector inlet and between the purge valve and the selector inlet. outlet or the outlet of the sample loop in a GC or the outlet of the pump in a gas sample selector The gas sample selector is switched to a position that allows the flow of purge gas into the gas sample selector flow path between the The multi-position selector valve is adapted to operate in various positions so that residual gas is removed from the loading conduit. The entire sample flow path of the GSS is thoroughly cleaned and the sample The new set of antennas is now ready to be installed. By using this workflow, the sources of contamination that contribute to carryover are This is handled and carryover is minimized.

[0045] The terminology used in this specification is for the purpose of describing particular embodiments and is not intended to be limiting. It is understood that the scope of the invention is not intended to be limiting. In addition to the technical and scientific meaning, the present teachings are generally understood and accepted in the art. It is as if.

[0046] The term "valve" generally refers to any structure, as defined in the structure. To change (switch or remove) the flow path out of and / or through the structure. Any structure can be adjusted (e.g., by turning on or off) Generally, the valve is substantially fluid-tight to prevent loss of fluid from the flow path. d-tight. Appropriate valves (e.g., selector valves, flush valves, and / or multiple ports) An example of a rotary valve is a rotary valve, such as a rotary valve that includes a stator and a rotor. The rotary valve includes a stator and a rotor, and one or both of the stator and the rotor are different rotary valves. The stator and rotor have adjacent surfaces, and one or both of the stator and rotor are The valve inlet and outlet(s) are configured to rotate relative to the other. In this embodiment, the passages or through holes in the stator. The rotor has grooves in the rotor surface. The stator and / or rotor are rotated. By connecting the valves, fluid paths connect different valve inlets with valve outlets. Examples of valves suitable as purge valves in the present device include flow switching valves, 3 Directional solenoid valves, including 2 position 3 / 4 / 6 / 8 or 10 port rotary / diaphragm valves, etc. Typical valve materials include metallic materials which may or may not be inert. The valve should desirably be kept at a short flush time to avoid trapping sample. In some embodiments, the flush valve has a low dead volume. It is a two-way valve having a

[0047] The term "conduit" generally refers to a conduit that is a passage through which a fluid passes at one point (e.g., the inlet of the conduit). ) to another point (e.g., the outlet of a conduit). Conduits may include any structure, but may also deliver fluid to intermediate points. A conduit may be flexible, rigid, or both in some or some parts. A flow path from one component (such as a gas source) to another component (such as a vent) It can be relatively long or short and / or linear or non-linear, so long as it provides For example, the conduit may be a long tube, a short fitting, or multiple entrances and / or The conduit may be a manifold having an inlet and an exit. In some embodiments, the conduit may have two or more inlets. Where pipes join or join together at one outlet, or where there are two or more conduits with one inlet A system may have multiple inlets and / or outlets, such as when the system is branched or split into multiple outlets. The conduit is measured by its length and inner diameter (i For example, an exemplary conduit is 10 Such conduits have lengths between 0.5 and 50 cm and an inside diameter of 0.02 inches. Of course, other lengths, internal diameters, and Conduits of any volume are also contemplated. The geometry of the conduits can vary widely and can include circular, rectangular, or rectangular shapes. Conduits may be of various geometric shapes (e.g., oval, square, D-shaped, trapezoidal, or other polygonal cross sections). , a rectangular cross section in one section and a trapezoidal cross section in another section) For conduits in the sample flow path, stainless steel or other metal tubing may be used. , which is often preferred to avoid contamination of plastics, fused silica, and other metals. Other materials such as fluorine, fluorine-containing ... and fluorine-containing fluorine may be used. The conduits and valves may optionally be provided with a non-activated coating. The nanoparticles may be coated with materials that improve inertness, such as with a coating of a polystyrene foam.

[0048] The term "connected" means that two components are in fluid communication. "Fluidly connected" means that the device is in fluid communication with the other device or is physically connected to the other device or is both. The term refers to when two components are in fluid communication and there is a direct A connection, or indirect connection, between two components where one or more other components are in the flow path. For example, a first component and a second component are , an outlet from a first component is physically connected to an inlet of a second component or where a conduit connects the first component and the second component, or when a fluid flows from a first component to a second component or vice versa, One or more intervening components, such as valves, pumps, or other structures, connect the two components. When the components are in fluid contact, they are connected by using ferrules. The devices may be physically connected in any suitable manner, such as by soldering, mounting, or other approaches. Generally, physical connections that are liquid tight and / or have minimal dead volume are required for the device. is desired.

[0049] In this disclosure, the terms "substantial" or "substantially" are used in a manner acceptable to those of ordinary skill in the art. The terms "substantially" and "about" mean a range or degree that is within the ability of a person skilled in the art to The term "about" generally means within an acceptable range or amount. For example, "about 10" means a number between 8.5 and 11.5. For example, "about the same" indicates that one of ordinary skill in the art would expect the items being compared to be the same. When a range of values ​​is stated in this disclosure, the exact value sequence is not intended to be limiting. It should be understood that both approximate values ​​are disclosed. It should also be understood that any of the values ​​above can be combined to form a range. be.

[0050] Unless otherwise specified, all technical and scientific terms used herein are defined by the It has the same meaning as commonly understood by a person skilled in the art to which the disclosure pertains. Any methods and materials similar or equivalent to those described herein may be used in the practice or testing of the present teachings. Any method and material may be used, some exemplary methods and materials are now described. All patents and publications cited therein are expressly incorporated herein by reference. Let us assume that.

[0051] As used in this specification and the appended claims, "a," "an," or "a The terms "a," "an," and "the" are used interchangeably unless the context clearly indicates otherwise. Thus, for example, "a conduit ( "a conduit" includes one conduit and multiple conduits. The terms "one," "second," "third," and other ordinal numbers refer to different aspects of the device and method. These terms are used herein to distinguish between different elements and are intended to provide quantitative limitations. References to a first valve position and a second valve position are to be understood to mean that the device has two valve positions. The term "compound" should not be construed to mean that the term "compound" refers only to a compound having a first element and a second element. A device may also include a third, fourth, fifth, etc. unless otherwise indicated.

[0052] Exemplary embodiments Exemplary embodiments provided by the presently disclosed subject matter include, but are not limited to, the following: However, the present invention is not limited to the above.

[0053] 1. A plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets flow to at least one selector valve outlet. a multi-position selector valve connected to the A flush valve having at least two flush valve positions, In the valve position, the flush valve provides a flow path between the flush valve inlet and the flush valve outlet. In another flush valve position, the flush valve has a flush valve vent port and , a flush valve providing a flow path between the flush valve inlet and / or the flush valve outlet; and Equipped with the selector valve outlet is fluidly connected to the flush valve inlet; A purge valve having at least two purge valve positions, Thus, the purge valve allows flow of purge gas to the purge valve inlet and the purge valve outlet; In the alternative purge valve position, the purge valve is connected to the purge valve inlet or the purge valve outlet. a purge valve for preventing gas flow; the flush valve outlet is fluidly connected to the purge valve inlet; a selector outlet for providing the gas sample to an analyzer; The selector outlet is fluidly connected to the purge valve outlet. A gas selector for selecting from the plurality of gas samples. Sample selector.

[0054] 2. The gas according to embodiment 1, wherein the flush valve vent port is fluidly connected to the surrounding area. Sample selector.

[0055] 3. A pump fluidly connected to the purge valve outlet; a flow restrictor fluidly connected to the purge valve outlet; The gas sample selection device according to any one of the preceding claims, further comprising either or both of: Selector.

[0056] 4. A plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets flow to at least one selector valve outlet. a multi-position selector valve connected to the A multiport valve having a plurality of valve ports, at least one of the valve ports having at least a multi-port valve, both of which are fluidly connected to the selector valve outlet; a pump fluidly connected to one of the valve ports; a flow restrictor fluidly connected to one or more of the valve ports; Equipped with The multi-port valve has at least two valve positions, and in one valve position, the multi-port valve creates a fluid connection between the multi-position selector valve and the pump and controls the flow of the fluid between the multi-position selector valve and the pump at different valve positions. The multi-port valve comprises a plurality of valves that create a fluid connection between the multi-position selector valve and the flow restrictor. A gas sample selector for selecting from a range of gas samples.

[0057] 5. A flush valve having at least two flush valve positions, one flush In the flush position, the flush valve provides a flow path between the flush valve inlet and the flush valve outlet. and in another flush valve position, the flush valve provides a flush valve vent port. a flush valve that provides a flow path between the flush valve and the flush valve inlet and / or the flush valve outlet; Valve and a selector-flush valve fluidly connecting at least one selector valve outlet to a flush valve inlet; Conduit and 5. The gas sample selector of embodiment 4, further comprising:

[0058] 6. A flush valve having at least two flush valve positions, one flush In the flush valve position, the flush valve inlet and the flush valve outlet are fluidly connected and In the flush valve position, the flush valve inlet and the flush valve outlet are not fluidly connected. A rush valve, a selector-flush valve fluidly connecting at least one selector valve outlet to a flush valve inlet; Conduit and 5. The gas sample selector of embodiment 4, further comprising:

[0059] 7. A purge valve having at least two purge valve positions, The purge valve allows the flow of purge gas to a purge valve inlet and a purge valve outlet. In another purge valve position, the purge valve is a purge valve to prevent the flow of purge gas; a purge valve conduit fluidly connecting the purge valve to the flush valve outlet; 7. The gas sample selector of embodiment 5 or embodiment 6, further comprising:

[0060] 8. The gas sample selector of embodiment 4, wherein the flow restrictor is a needle valve.

[0061] 9. A multi-port valve is a rotary valve with 6, 8, 10 or more ports. 5. The gas sample selector of embodiment 4.

[0062] 10. The purge valve is connected to a purge gas source, such as air, helium, hydrogen, nitrogen, and argon. 5. The gas sump of claim 1 or 4, which is fluidly connected to a mixture of argon and methane. Selector.

[0063] 11. In signal communication with one or more of the multiple position selector valve, flush valve, and / or purge valve. 5. The gas sample selector according to claim 1 or 4, further comprising a controller according to the embodiment. .

[0064] 12. A gas chromatograph having a chromatograph inlet; A gas sample selector as described in embodiment 1; wherein the selector outlet is fluidly connected to the chromatograph inlet. .

[0065] 13. A gas chromatograph having a chromatograph inlet; A gas sample selector as described in embodiment 5. wherein the selector outlet is fluidly connected to the chromatograph inlet. .

[0066] 14. A plurality of gas sample containers fluidly connected to the selector inlet of the gas sample selector. and at least one of the gas sample containers is a high pressure gas sample container. In accordance with embodiment 12 or embodiment 13, one or more of the sample containers is a low pressure gas sample container. 14. The gas analyzer system of embodiment 13.

[0067] 15. The gas chromatograph includes a sample loop in fluid communication with the selector outlet. 14. A gas analyzer system as described in embodiment 12 or embodiment 13.

[0068] 16. The gas sample selector further comprises a selector return port, and the gas chromatograph a chromatograph outlet, the selector return port being fluidly connected to the chromatograph outlet. 14. The gas analyzer system of claim 12 or 13,

[0069] 17. The chromatograph includes a sample loop, the sample loop being connected to a selector outlet. 14. A gas analyzer system as described in embodiment 12 or embodiment 13, connected to

[0070] 18. The flush valve is in a position that connects the flush valve inlet to the flush valve outlet, or and the purge valve is positioned to prevent the flow of purge gas to the purge valve inlet and the purge valve outlet. and flowing the sample gas from the selector inlet to the selector outlet while in the A method for operating the gas sample selector according to claim 1. The method comprises the steps of: , can be loaded into the sample loop, from which the sample gas is delivered to the column. After the column is loaded, the remaining sample gas in the gas sample selector is removed. Therefore, it is desirable to carry out the following steps: switching the flush valve, thereby venting the flush valve and Connect the rush valve outlet and disconnect the flush valve inlet from the flush valve outlet, thereby and switching the flush valve to prevent flow of sample gas downstream of the flush valve. Flowing a purge gas through a purge valve port, whereby the purge gas The gas flows to the selector outlet and the flush valve vent, and the gas flows between the flush valve and the selector outlet. removing the sample gas from the flow path between the can be implemented.

[0071] 19. One of the selector inlets is attached directly or indirectly to a sample container. And Decoupling the sample container from the selector inlet; Turn the flush valve off so that the flush valve inlet and the flush valve outlet are fluidly connected. To replace and Purge gas is directed from the purge valve through a selector inlet and / or through a multi-position selector valve. And let it flow 20. The method of embodiment 18, further comprising:

[0072] 20. Stop the flow of purge gas and disconnect the sample container from the selector inlet. And, connecting a new sample container to the inlet of the selector; While the flush valve inlet is fluidly connected to the flush valve outlet, a new sample is added to the selected flowing from the selector inlet, through the multiple position selector valve and out the selector outlet; 20. The method of embodiment 18, further comprising:

[0073] 21. The step of connecting the two or more new gas samples to the gas sample selector connecting the selector inlet to the selector inlet, A first gas sample is connected to the gas sample selector and a multi-position selector valve is connected to the first gas sample. and switching the valve to a selected position and discharging the flush valve inlet and the flush valve outlet. Position the flush valve so that it is connected and close the and discharging the first gas sample from the selector inlet to the gas sump. loading the filter by flowing the filter to a selector outlet of the filter selector; After loading the first gas sample, the remaining first gas sample is flushed. and optionally a flush valve vent to separate the valve inlet from the flush valve outlet. and switching the flush valve to connect the flush valve outlet and the purge valve port. a purge valve for connecting the port to the purge valve outlet and, optionally, to the purge valve inlet. and a purge gas is introduced to remove the remaining first gas sample. from the fill valve to the selector outlet and, optionally, to the flush valve vent; and purging by A second gas sample is connected to the gas sample selector and the multi-position selector valve is connected to the second gas sample. and switching the valve to a selected position and discharging the flush valve inlet and the flush valve outlet. Position the flush valve so that it is connected and close the and discharging a second gas sample from the selector inlet to the gas sump. and loading the filter by flowing the filter to the selector outlet of the filter selector. 21. The method of embodiment 20, further comprising:

[0074] 22. Multiport valves with two or more positions shall have a valve between the purge valve outlet and the selector outlet. and connected prior to the step of flowing the gas sample from the selector inlet to the selector outlet. The sample gas in the sample container should flow through a pump or flow restrictor. and switching the multi-port valve to a valve position based on the determination. The multi-port valve has at least two valve positions, and in one of the valve positions, The port valve creates a fluid connection between the multiple position selector valve and the pump and is connected to another valve position. In the embodiment, the multi-port valve creates a fluid connection between the multi-position selector valve and the flow restrictor. 20. The method according to embodiment 18.

[0075] 23. The gas sample selector is a gas sampler that includes a gas chromatograph with a sample loop. The gas sample selector is fluidly connected to the analyzer system and the outlet of the gas sample selector is connected to the The method includes: feeding a sample gas and / or a purge gas to a gas sample selection inlet; flowing the sample from the outlet of the selector into a gas chromatograph through a sample loop; 20. The method of embodiment 18.

[0076] 24. After the sample gas flows from the selector inlet to the selector outlet, the sample loop , which is fluidly connected to a gas chromatography column, which in turn is fluidly connected to a gas sample selector. 24. The method of claim 23, wherein the state is switched back to a connected state.

[0077] 25. After the sample gas fills the sample loop, the flush valve closes. The port is switched to connect to the flush valve vent, thereby 24. The method of embodiment 23, wherein the pressure is allowed to equilibrate with the surrounding area.

[0078] 26. A plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets flow to at least one selector valve outlet. a multi-position selector valve connected to the A flush valve having two flush valve positions, in one of the valve positions The flush valve inlet and the flush valve outlet are fluidly connected, and in another valve position of the valve position Therefore, the flush valve inlet and the flush valve outlet are not fluidly connected. Equipped with the selector valve outlet is fluidly connected to the flush valve inlet; A purge valve having at least two purge valve positions, The purge valve allows flow of purge gas to the purge valve inlet and / or the purge valve outlet. In another purge valve position, the purge valve is a purge valve for preventing the flow of purge gas; the flush valve outlet is fluidly connected to the purge valve inlet; a selector outlet for providing the gas sample to an analyzer; The selector outlet is fluidly connected to the purge valve outlet. A gas selector for selecting from the plurality of gas samples. Sample selector.

[0079] The above description of exemplary or preferred embodiments is intended to provide a general understanding of the present invention as defined by the embodiments. The above should be construed as illustrative rather than limiting. Numerous variations and combinations of the above features are possible from the invention described in the embodiments. Such modifications are within the scope of the present invention. and all such variations are intended to be included within the scope of the appended embodiments. All references cited herein are incorporated herein by reference in their entirety. shall be part of.

Claims

1. a plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets are connected to the at least one selector valve outlet. a multi-position selector valve fluidly connected to the A flush valve having at least two flush valve positions, In the valve position, the flush valve defines a flow path between the flush valve inlet and the flush valve outlet. In another flush valve position, the flush valve has a flush valve vent port. providing a flow path between the flush valve inlet and the flush valve outlet; Flush valve and Equipped with the selector valve outlet is fluidly connected to the flush valve inlet; A purge valve having at least two purge valve positions, The purge valve controls the flow of purge gas to the purge valve inlet and the purge valve outlet. In another purge valve position, the purge valve is connected to the purge valve inlet or the purge valve outlet. a purge valve preventing flow of purge gas to the valve outlet; the flush valve outlet is fluidly connected to the purge valve inlet; a selector outlet for providing the gas sample to an analyzer; The selector outlet is fluidly connected to the purge valve outlet. A gas sample selector.

2. 10. The gas supply system of claim 1, wherein the flush valve vent port is fluidly connected to an ambient area. Sample selector.

3. a pump fluidly connected to the purge valve outlet; a flow restrictor fluidly connected to the purge valve outlet; 3. The gas sample selector of claim 1 or 2, further comprising either or both of:

4. a plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets are connected to the at least one selector valve outlet. a multi-position selector valve fluidly connected to the A multiport valve having a plurality of valve ports, at least one of the valve ports being a multi-port valve fluidly connected to the at least one selector valve outlet; a pump fluidly connected to one of the valve ports; a flow restrictor fluidly connected to one or more of the valve ports; Equipped with The multi-port valve has at least two valve positions, and in one valve position, the multiple port valve A port valve creates a fluid connection between the multi-position selector valve and the pump and is operable to select another valve position. wherein the multi-port valve is a fluid connection between the multi-position selector valve and the flow restrictor. A gas sample selector that selects between multiple gas samples to create a connection.

5. A flush valve having at least two flush valve positions, In the valve position, the flush valve defines a flow path between the flush valve inlet and the flush valve outlet. In another flush valve position, the flush valve has a flush valve vent port. providing a flow path between the flush valve inlet and the flush valve outlet; A flush valve; A selector-flush valve fluidly connecting the at least one selector valve outlet to the flush valve inlet. Rush duct and The gas sample selector of claim 4 further comprising:

6. A flush valve having at least two flush valve positions, In the valve position, the flush valve inlet and the flush valve outlet are fluidly connected. In the flush valve position, the flush valve inlet and the flush valve outlet are fluidly connected. The flush valve is not A selector-flush valve fluidly connecting the at least one selector valve outlet to the flush valve inlet. Rush duct and The gas sample selector of claim 4 further comprising:

7. A purge valve having at least two purge valve positions, The purge valve controls the flow of purge gas to the purge valve inlet and the purge valve outlet. In another purge valve position, the purge valve is connected to the purge valve inlet or the purge valve outlet. a purge valve preventing flow of purge gas to the valve outlet; a purge valve conduit fluidly connecting the purge valve to the flush valve outlet; 7. A gas sample selector as claimed in claim 5 or 6, further comprising:

8. 5. The gas sample selector of claim 4, wherein the flow restrictor is a needle valve.

9. The multi-port valve is a rotary valve having 6, 8, 10 or more ports.

5. The gas sample selector of claim 4.

10. 5. The gas sump of claim 1 or 4, wherein the purge valve is fluidly connected to a purge gas source. Selector.

11. one or more of the multiple position selector valve, the flush valve, and / or the purge valve and a signal 5. The gas sample selector of claim 1 or 4, further comprising a communication state controller.

12. a gas chromatograph having a chromatograph inlet; The gas sample selector of claim 1 ; Equipped with the selector outlet is fluidly connected to the chromatograph inlet. 。

13. a gas chromatograph having a chromatograph inlet; A gas sample selector as claimed in claim 5; Equipped with the selector outlet is fluidly connected to the chromatograph inlet. 。

14. a plurality of gas sample containers fluidly connected to the selector inlets of the gas sample selector; wherein one or more of the gas sample containers is a high pressure gas sample container; 12. The method of claim 11, wherein one or more of the gas sample containers is a low pressure gas sample container.

14. The gas analyzer system according to claim 13.

15. The gas chromatograph includes a sample loop in fluid communication with the selector outlet.

14. The gas analyzer system of claim 12 or 13.

16. The gas sample selector further comprises a selector return port. a chromatograph outlet, and the selector return port is connected to the chromatograph outlet.

14. The gas analyzer system of claim 12 or 13, fluidly connected to

17. The chromatograph includes a sample loop, the sample loop being connected to the selector outlet.

14. The gas analyzer system of claim 12 or 13, fluidly connected to

18. The flush valve is in a position connecting the flush valve inlet to the flush valve outlet. and the purge valve controls the flow of purge gas to the purge valve inlet and the purge valve outlet. a selector inlet to a selector outlet while in said flow preventing position; And switching said flush valve, thereby venting said flush valve and and the flush valve outlet, and disconnect the flush valve inlet from the flush valve outlet. a disconnection valve that disconnects the flush valve and thereby prevents the flow of sample gas downstream of the flush valve; To replace and flowing a purge gas through said purge valve port, thereby The gas flows to the selector outlet and the flush valve vent, and removing the sample gas from the flow path between the selector outlet and the flow path; 2. The method of operating the gas sample selector of claim 1, comprising:

19. One of the selector inlets is attached directly or indirectly to a sample container. The method comprises: Decoupling the sample container from the selector inlet; The flush valve is connected to the flush valve inlet and the flush valve outlet. switching a valve; A purge gas is supplied from the purge valve through the selector inlet and / or through the multiple position Flow through the selector valve 20. The method of claim 18, further comprising:

20. Stop the flow of purge gas and disconnect the sample container from the selector inlet. To separate and connecting a new sample container to the inlet of the selector; While the flush valve inlet is fluidly connected to the flush valve outlet, a sample is passed from the inlet of the selector through the multiple position selector valve and to the selector outlet. Let it flow out of your mouth.

20. The method of claim 18, further comprising:

21. The step of connecting may include connecting two or more new gas samples to the gas sample selector. and connecting the selector inlet of switching the multi-position selector valve to a position where a first gas sample is selected; The flush valve is connected to the flush valve inlet and the flush valve outlet. positioning a purge valve to prevent flow of purge gas; and positioning the purge valve to prevent flow of purge gas. and discharging the first gas sample from a selector inlet of the gas sample selector. and directing the first gas sample to the gas sample selector by flowing the first gas sample to a gas sample selector outlet. To download and to separate the flush valve inlet from the flush valve outlet, and optionally , the flush valve vent and the flush valve outlet to connect the flush valve switching a valve and connecting the purge valve port to the purge valve outlet, and optionally switching the purge valve to connect to the purge valve inlet; and a purge gas is passed from the purge valve to the selector outlet to remove the gas sample. and optionally, to the flush valve vent. purging the remaining first gas sample after the loading of the sample; switching the multi-position selector valve to a position where a second gas sample is selected; The flush valve is connected to the flush valve inlet and the flush valve outlet. positioning a purge valve to prevent flow of purge gas; and positioning the purge valve to prevent flow of purge gas. and transferring the second gas sample from a selector inlet to the gas sample selector. and directing the second gas sample to the gas sample selector by flowing the second gas sample to the gas sample selector outlet. To download and 21. The method of claim 20, further comprising:

22. A multi-port valve having two or more positions is disposed between the purge valve outlet and the selector outlet. and the method includes directing the sample gas from the selector inlet to the selector outlet. Prior to the flowing step, the sample gas in the connected sample container is pumped. and determining whether the flow should flow through a flow restrictor or a flow path of the multi-port valve. and switching the valve position based on the setting; The multi-port valve has at least two valve positions, and in one of the valve positions The multi-port valve creates a fluid connection between the multi-position selector valve and a pump. In another of the valve positions, the multiport valve is coupled to the multiposition selector valve and a flow restriction.

20. The method of claim 18, further comprising creating a fluid connection between the vessel and the

23. The gas sample selector includes a gas chromatograph having a sample loop. the outlet of the gas sample selector is fluidly connected to the gas chromatograph system; a first inlet of the chromatograph; The method further comprises: passing the sample gas and / or the purge gas through the gas sample selector. from the outlet into the gas chromatograph through the sample loop.

20. The method of claim 18, comprising:

24. After the sample gas flows from the selector inlet to the selector outlet, the sample loop , fluidly connected to a gas chromatography column, and then to the gas sample selector and 24. The method of claim 23, wherein the first and second connections are switched back to a physical connection state.

25. After the sample gas fills the sample loop, the flush valve a flush valve outlet to connect to said flush valve vent, thereby 24. The method of claim 23, further comprising allowing pressure in the sample loop to equilibrate with the surrounding area. The method described.

26. a plurality of selector inlets for receiving gas samples; A multiple position selector valve having a plurality of selector valve inlets and at least one selector valve outlet. Thus, in different valve positions, different selector valve inlets are connected to the at least one selector valve outlet. a multi-position selector valve fluidly connected to the A flush valve having two flush valve positions, In the embodiment, the flush valve inlet and the flush valve outlet are fluidly connected, and the valve position In another valve position, the flush valve inlet and the flush valve outlet are not fluidly connected. Flush valve and Equipped with the selector valve outlet is fluidly connected to the flush valve inlet; A purge valve having at least two purge valve positions, The purge valve controls the flow of purge gas to the purge valve inlet and / or the purge valve outlet. In another purge valve position, the purge valve allows flow through the purge valve inlet or the a purge valve that prevents flow of purge gas to a purge valve outlet; the flush valve outlet is fluidly connected to the purge valve inlet; a selector outlet for providing the gas sample to an analyzer; The selector outlet is fluidly connected to the purge valve outlet. A gas sample selector.

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