Emulsifier composition

Abstract

To provide an emulsifier that can be obtained from naturally derived components and can produce an oil-in-water emulsion composition without the need for heating during emulsification.SOLUTION: An emulsifier composition for an oil-in-water emulsion composition is used, in which the following components (A) and (B) are contained, the mass ratio of components (A1) and (A2) is 95:5 to 15:85, and component (A) is dispersed in water. (A) A lipid composition composed of the following components (A1) and (A2): (A1) one or more selected from mono- or di-esters of fatty acids having 8 to 22 carbon atoms and polyglycerol having a polymerization degree of 6 to 22, and monoesters of fatty acids having 8 to 22 carbon atoms and sucrose; and (A2) a phospholipid. (B) Water.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to an emulsifier composition used in the production of an oil-in-water emulsion composition. [Background technology]

[0002] In the field of cosmetics, oil-in-water emulsion compositions in the form of lotions, milky lotions, and creams are widely used for the purpose of simultaneously supplying water-soluble and oily components to the skin or hair, or for the purpose of improving the usability and feel of oily components. In general, emulsifiers are essential for the production of such oil-in-water emulsion compositions, and a wide variety of emulsifiers have been used in the past. However, in recent years, from the perspective of sustainability, there has been a demand for the use of emulsifiers derived from natural sources.

[0003] Polyglycerol fatty acid esters and sucrose fatty acid esters are nonionic surfactants that are synthesized from naturally derived ingredients and are safe enough to be used in food applications, and are widely used as raw materials for cosmetics and topical skin preparations. Lecithin is a generic name for naturally derived phospholipids obtained from animals or plants, and is very safe for humans, does not irritate the skin, and has a moisturizing effect and a unique, excellent feel when used, so it is widely used as a raw material for cosmetics and topical skin preparations.

[0004] As exemplified in Patent Documents 1 and 2, attempts to use a combination of polyglycerol fatty acid ester and lecithin, or sucrose fatty acid ester and lecithin, as an emulsifier for an oil-in-water emulsion composition are already known. However, when an oil-in-water emulsion composition is generally produced using such an emulsifier, the emulsifier and the oil agent are preheated and stirred to prepare an oil phase, and the obtained oil phase is added to a preheated aqueous phase and stirred and mixed. However, from the viewpoint of reducing environmental load in recent years, it is desired to produce an oil-in-water emulsion composition without the need for heating during emulsification. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] JP 2006-282568 A [Patent Document 2] JP 2011-057587 A Summary of the Invention [Problem to be solved by the invention]

[0006] An object of the present invention is to provide an emulsifier which can be obtained from a naturally-derived component and which enables the production of an oil-in-water emulsion composition without requiring heating during emulsification. [Means for solving the problem]

[0007] Means for Solving the Problems The present inventors have conducted intensive research to solve the above-mentioned problems, and as a result have found that the above-mentioned problems can be solved by an emulsifier composition comprising the following components (A) and (B), wherein the mass ratio of components (A1) to (A2) is 95:5 to 15:85, and component (A) is dispersed in water, and have thus completed the present invention. (A) A lipid composition comprising the following components (A1) and (A2): (A1) One or more selected from mono- or diesters of fatty acids having 8 to 22 carbon atoms and polyglycerols having a degree of polymerization of 6 to 22, and monoesters of fatty acids having 8 to 22 carbon atoms and sucrose. (A2) Phospholipids (B)Water Effect of the Invention

[0008] The emulsifier composition of the present invention can be obtained from naturally derived components, does not require heating during emulsification, and can produce an oil-in-water emulsion composition by stirring and mixing with an oily component, regardless of the polarity of the oily component. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0009] The emulsifier composition of the present invention is characterized by containing the following components (A) and (B). (A) A lipid composition comprising the following components (A1) and (A2): (A1) One or more selected from mono- or diesters of fatty acids having 8 to 22 carbon atoms and polyglycerols having a degree of polymerization of 6 to 22, and monoesters of fatty acids having 8 to 22 carbon atoms and sucrose. (A2) Phospholipids (B)Water

[0010] The mono- or diester of a fatty acid having 8 to 22 carbon atoms and a polyglycerol having a degree of polymerization of 6 to 22, which is the component (A1) used in the present invention, is preferably a mono- or diester of a fatty acid having 12 to 18 carbon atoms and a polyglycerol having an average degree of polymerization of 6 to 10, and more preferably a mono- or diester of a fatty acid selected from lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid and isostearic acid and a polyglycerol having an average degree of polymerization of 6 to 10. Specific examples include polyglyceryl-6,-8,-10 laurate, polyglyceryl-6,-8,-10 myristate, polyglyceryl-6,-8,-10 palmitate, polyglyceryl-6,-8,-10 stearate, polyglyceryl-6,-8,-10 oleate, polyglyceryl-6,-8,-10 isostearate, polyglyceryl-6,-8,-10 dilaurate, polyglyceryl-6,-8,-10 dimyristate, polyglyceryl-6,-8,-10 dipalmitate, polyglyceryl-6,-8,-10 distearate, polyglyceryl-6,-8,-10 dioleate, polyglyceryl-6,-8,-10 diisostearate, etc. These may be used alone or in combination of two or more. Of these, polyglyceryl-10 laurate, polyglyceryl-10 myristate, polyglyceryl-10 palmitate, polyglyceryl-10 stearate, polyglyceryl-10 oleate, polyglyceryl-10 isostearate, polyglyceryl-10 dilaurate, polyglyceryl-10 dimyristate, polyglyceryl-10 dipalmitate, polyglyceryl-10 distearate, polyglyceryl-10 dioleate, and polyglyceryl-10 diisostearate are more preferred, and polyglyceryl-10 laurate, polyglyceryl-10 myristate, polyglyceryl-10 palmitate, polyglyceryl-10 stearate, polyglyceryl-10 oleate, and polyglyceryl-10 isostearate are even more preferred.

[0011] The monoester of sucrose and a fatty acid having 8 to 22 carbon atoms, component (A1), used in the present invention is preferably a monoester of sucrose and a fatty acid selected from lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, isostearic acid, arachidic acid, and behenic acid. Specific examples include sucrose laurate, sucrose myristate, sucrose palmitate, sucrose stearate, sucrose oleate, sucrose isostearate, sucrose arachidic acid, and sucrose behenate. These may be used alone or in combination of two or more. Of these, sucrose laurate, sucrose myristic acid, sucrose palmitate, sucrose stearate, sucrose oleate, and sucrose isostearate are more preferred.

[0012] Examples of the phospholipids of component (A2) used in the present invention include diacylglycerophospholipids having polar groups such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, and phosphatidic acid; lecithin obtained from plants such as soybean, rapeseed, sunflower, safflower, peanut, cottonseed, corn, rice, and barley, and egg yolk, and hydrogenated products thereof. These phospholipids may be used alone or in combination of two or more. Among these, lecithin and hydrogenated products thereof are preferred from the viewpoint of availability and further exerting the effects of the present invention. Lecithin with different phosphatidylcholine (hereinafter, PC) contents depending on the degree of purification is commercially available, and any PC content can be used in the present invention. From the viewpoint of dispersion stability of the resulting emulsifier composition, it is preferable to use one with a PC content of 40% by mass or more, more preferably 50% by mass or more.

[0013] The water of component (B) used in the present invention is not particularly limited, and can be purified water, ion-exchanged water, distilled water, natural water, deep sea water, hydrogen water, etc. In addition, the pH of the water may be adjusted with an acid, an alkali, a buffering agent, a chelating agent, etc., or a water-soluble component such as a preservative may be added.

[0014] In the present invention, the mass ratio of components (A1) and (A2) is 95:5 to 15:85. If the mass ratio of components (A1) and (A2) is outside this range, an oil-in-water emulsion composition cannot be formed even if the components are stirred and mixed with an oily component at a temperature near room temperature without heating. From the viewpoint of further exerting the effects of the present invention, the mass ratio of components (A1) and (A2) is preferably 92:8 to 18:82, more preferably 90:10 to 20:80.

[0015] The content of component (A) in the emulsifier composition of the present invention is not particularly limited since it may be appropriately changed depending on the amount of the oily component to be emulsified, but the lower limit of the content is usually 0.01% by mass or more, preferably 0.05% by mass or more. The upper limit of the content is 25% by mass or less, preferably 20% by mass or less, from the viewpoint of the dispersion stability of the emulsifier composition.

[0016] The emulsifier composition of the present invention is characterized in that the lipid composition consisting of component (A), i.e., components (A1) and (A2), is dispersed in water. Component (A) being dispersed in water means that components (A1) and (A2) are dispersed in water in a fully mixed state. When components (A1) and (A2) are separately dispersed in water, they cannot form an oil-in-water emulsion composition even if they are stirred and mixed with an oily component at a temperature around room temperature without heating.

[0017] As described above, component (A) of the present invention needs to be dispersed in water in a state in which components (A1) and (A2) are sufficiently mixed. In order to disperse component (A) in water in such a state, components (A1) and (A2) can be mixed in advance and then added to water and mixed by stirring, or components (A1) and (A2) can be added separately to unagitated water and then mixed by stirring.

[0018] The emulsifier composition of the present invention may further contain a polyhydric alcohol as component (C). As described above, one method for dispersing component (A) in water is to previously mix components (A1) and (A2) and add the mixture to water and stir and mix. However, it is difficult to previously mix only components (A1) and (A2) in scaled-up industrial production. From this viewpoint, a polyhydric alcohol can be used as component (C) in the preparation of the emulsifier composition of the present invention. Specifically, components (A) and (C) are stirred and mixed to prepare a polyhydric alcohol solution, and water is added to the resulting polyhydric alcohol solution while stirring, or the polyhydric alcohol solution is added to water while stirring, so that components (A1) and (A2) are dispersed in water in a fully mixed state as component (A), making it easy to prepare the emulsifier composition of the present invention. In this case, the amount of component (C) used is not particularly limited as long as component (A) is sufficiently dispersed in component (C), but it is usually at least 2 times by mass, preferably at least 2.5 times by mass, of component (A).

[0019] Examples of the polyhydric alcohols used in the present invention as component (C) include dihydric alcohols such as ethylene glycol, propylene glycol, 1,3-propanediol, 1,2-butylene glycol, 1,3-butylene glycol, 2,3-butylene glycol, tetramethylene glycol, hexylene glycol, octylene glycol, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and 1,2-decanediol; glycerin, trimethylolpropane, and 1,2,6-hexanetriol. trihydric alcohols such as glycerol; sugar alcohols such as sorbitol, xylitol, erythritol, maltitol, mannitol; glyceryl ethers such as ethylglycerin, butylglycerin, hexylglycerin, ethylhexylglycerin; polyhydric alcohol polymers such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol, dipropylene glycol, tripropylene glycol, polypropylene glycol, diglycerin, triglycerin, tetraglycerin, polyglycerin, etc. These may be used alone or in combination of two or more. Among these, glycerin, propylene glycol, 1,3-propanediol, dipropylene glycol, 1,3-butylene glycol, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, and 1,2-octanediol are preferred, and 1,3-butylene glycol, glycerin, 1,2-pentanediol, and 1,2-hexanediol are most preferred.

[0020] The emulsifier composition of the present invention obtained as described above can be stirred and mixed with an oily component to produce an oil-in-water emulsion composition. The emulsifier composition of the present invention may be directly stirred and mixed with an oily component to produce an oil-in-water emulsion composition, or it may be appropriately diluted with water so that the content of component (A) is the content required for emulsifying the oily component, and then stirred and mixed with the oily component to produce an oil-in-water emulsion composition. In addition, when the oily component used has already been emulsified into emulsion particles by another emulsifier, when it is stirred and mixed with the emulsifier composition of the present invention, an oil-in-water emulsion composition is apparently produced, but naturally such an oil-in-water emulsion composition does not correspond to the oil-in-water emulsion composition of the present invention, since the emulsion particles are not formed by the emulsifier composition of the present invention.

[0021] The emulsifier composition of the present invention has a technical feature that an oil-in-water emulsion composition can be produced at a temperature near room temperature without the need for heating in the emulsification step of stirring and mixing with an oily component. The reason why the emulsifier composition of the present invention can produce an oil-in-water emulsion composition without heating is believed to be that in the emulsifier composition of the present invention, component (A) forms a fine lipid membrane structure and disperses in water. The lipid membrane structure means vesicles, bicelles, etc. When an oil-in-water emulsion composition is produced using an emulsifier in a general manner, the formed emulsion particles are in a state in which the lipophilic group in the molecule of the emulsifier faces the oil phase and the hydrophilic group faces the water phase at the water / oil interface, thereby preventing the emulsion particles from coalescing. On the other hand, the emulsifier composition of the present invention forms emulsion particles by adhering the fine lipid membrane structure made of component (A) to the surface of the oil droplets while maintaining the shape of the structure, thereby preventing coalescence. For this reason, the emulsifier composition of the present invention is believed to be unnecessary to heat during emulsification. Therefore, the emulsion particles formed by the emulsifier composition of the present invention have a significantly different state at the water / oil interface from emulsion particles produced by a general method. Note that, in the present invention, heating is not excluded when producing an oil-in-water emulsion composition using the emulsifier composition of the present invention, and heating may be applied as necessary.

[0022] In the oil-in-water emulsion composition produced by stirring and mixing the emulsifier composition of the present invention and an oily component (also referred to as the oil-in-water emulsion composition of the present invention), the method for stirring and mixing the emulsifier composition and the oily component is not particularly limited and may be any method generally used for producing oil-in-water emulsion compositions.

[0023] In the production of the oil-in-water emulsion composition of the present invention, the amount of the emulsifier composition of the present invention used may be adjusted appropriately according to the amount of oily components to be blended in the oil-in-water emulsion composition, and is not particularly limited. As shown in the test in the examples described below, the emulsifier composition of the present invention has the ability to emulsify up to 50 times the mass of the oily components of the component (A) when the component (A1) is a mono- or diester of a fatty acid having 8 to 22 carbon atoms and a polyglycerin having a polymerization degree of 6 to 22, and has the ability to emulsify up to 30 times the mass of the oily components of the component (A) when the component (A1) is a monoester of a fatty acid having 8 to 22 carbon atoms and sucrose. Therefore, the emulsifier composition of the present invention is preferably used so that the content of the component (A) contained in the oil-in-water emulsion composition is 1 / 50 times (0.02 times) or 1 / 30 times (0.033 times) or more of the oily components to be blended in the oil-in-water emulsion composition.

[0024] The amount of oily component blended in the oil-in-water emulsion composition of the present invention is not particularly limited as long as it is blended in such an amount that an oil-in-water emulsion composition is formed, but it is generally blended in an amount of about 0.01 to 60% by mass, preferably about 0.1 to 55% by mass in the oil-in-water emulsion composition.

[0025] The oily component used in the oil-in-water emulsion composition of the present invention is not particularly limited, and one or more of the oily components generally used in cosmetics can be used. In general, when an emulsifier is used to produce an oil-in-water emulsion composition, it is necessary to adjust the HLB of the emulsifier according to the polarity (required HLB) of the oily component used, but the emulsifier composition of the present invention can produce an oil-in-water emulsion composition regardless of the polarity of the oily component. Specific examples of the oily component used in the oil-in-water emulsion composition of the present invention are described below, but the present invention is not limited to these, and may contain various oil-soluble components that dissolve in the exemplified oily components.

[0026] Specific examples of the oily component used in the oil-in-water emulsion composition of the present invention include hydrocarbons such as dodecane, isododecane, hexadecane, isohexadecane, (C13-15) alkanes, liquid paraffin, heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, and petrolatum; coconut oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, and the like. Vegetable oils and fats such as corn oil, hazelnut oil, kukui nut oil, rosehip oil, argania spinosa kernel oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, camellia oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cacao butter, jojoba oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, and hydrogenated jojoba oil; methylheptyl laurate, isopropyl myristate, methylheptyl myristate, hexyldecyl myristate, octyl myristate Ludodecyl, isopropyl palmitate, methylheptyl palmitate, ethylhexyl palmitate, cetyl palmitate, octyldodecyl palmitate, cetyl ethylhexanoate, hexyldecyl ethylhexanoate, isotridecyl isononanoate, isononyl isononanoate, ethylhexyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, ethyl oleate, oleyl oleate, octyldodecyl oleate, isopropyl isostearate Monoalcohol carboxylates such as pyruve, methylheptyl isostearate, octyldodecyl isostearate, octyldodecyl ricinoleate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, isopropyl lanolate, octyldodecyl lanolate, diethylhexyl succinate, diisopropyl adipate, diisobutyl adipate, diethylhexyl adipate, diethyl sebacate, diisopropyl sebacate, diethylhexyl sebacate, dibutyloctyl sebacate, and dicaprylyl carbonate;Oxyacid esters such as cetyl lactate, hydrogenated castor oil monoisostearate, γ-erucalactone, diisostearyl malate, and triethyl citrate; glyceryl triethylhexanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, glyceryl tri(caprylic acid / capric acid), glyceryl tri(caprylic acid / capric acid / myristic acid / stearic acid), glyceryl behenate eicosane diate, trimethylolpropane triethylhexanoate, trimethylolpropane triisostearate, neopentyl glycol diethylhexanoate, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol diethylhexanoate, propylene glycol dioleate, pentaerythrityl tetraethylhexanoate, ditrimethylolpropane triethylhexanoate, and triethylhexane. Polyhydric alcohol fatty acid esters such as pentaerythrityl ester, dipentaerythrityl hydroxystearic acid / stearic acid / rosin acid, diglyceryl diisostearate, diglyceryl tetraisostearate, 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl-1,5-pentanediol dineopentanoate; alkyl ethers such as dicaprylyl ether; di-N-lauroyl-L-glutamic acid acyl amino acid esters such as octyldodecyl, N-lauroyl-L-glutamic acid di(phytosteryl / octyldodecyl), N-lauroyl-L-glutamic acid di(cholesteryl / octyldodecyl), N-lauroyl-L-glutamic acid di(cholesteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl / behenyl / octyldodecyl), and N-lauroyl sarcosine isopropyl;Phytosteryl oleate, phytosteryl hydroxystearate, phytosteryl isostearate, phytosteryl lanolate, phytosteryl macadamiate, phytosteryl sunflower seed oil, phytosteryl rice bran oil, cholesteryl acetate, cholesteryl nonanoate, cholesteryl oleate, cholesteryl 12-hydroxystearate, cholesteryl isostearate, cholesteryl lanolate, cholesteryl macadamiate, Sterol esters such as cholesteryl sunflower seed oil fatty acid, cholesteryl rice bran oil fatty acid, cholesteryl soft lanolin fatty acid, cholesteryl hard lanolin fatty acid, cholesteryl long-chain branched fatty acid, cholesteryl long-chain α-hydroxy fatty acid; diisopropyl dimer dilinoleate, diisostearyl dimer dilinoleate, di(isostearyl / phytosteryl) dimer dilinoleate, phytosteryl / behenyl dimer dilinoleate, phytosteryl dimer dilinoleate / isostearyl / cetyl / stearyl / behenyl), dimer dilinoleyl dimer dilinoleate, dimer dilinoleyl diisostearate, dimer dilinoleyl hydrogenated rosin condensate, dimer dilinoleic acid hydrogenated castor oil, hydroxyalkyl dimer dilinoleyl ether and other dimer acid or dimer diol derivatives; lanolin, liquid lanolin, hard lanolin, reduced lanolin, adsorption refined lanolin, lanolin alcohol and other lanolins; dimethicone, highly polymerized dimethicone, cyclopentadiene, etc. silicones such as dimethicone, phenyl trimethicone, diphenyl dimethicone, phenyl dimethicone, and dimethiconol; higher alcohols such as cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, arachyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, selachyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, and 2-octyldodecanol;Examples of higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids, long-chain α-hydroxy fatty acids, lanolin fatty acids, dimer acids, and hydrogenated dimer acids.

[0027] Component (A) of the emulsifier composition of the present invention may further contain, as component (A3), a component that can be encapsulated in the membrane of the lipid membrane structure formed by component (A). Specific examples of component (A3) used in the present invention include one or more selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid, and coenzyme Q10. More specific examples of ceramides include ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, ceramide 7, sphingosine, and phytosphingosine. Examples of sterols include cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, desmosterol, stigmasterol, sitosterol, campesterol, brassicasterol, phytosterol, ergosterol, and oryzanol. Examples of carotenoids include carotene, lycopene, cryptoxanthin, lutein, zeaxanthin, astaxanthin, crocetin, fucoxanthin, etc. Examples of tocopherols include α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol nicotinate, etc.

[0028] When component (A) contains component (A3), the content of component (A3) in component (A) is 36% by mass or less, preferably 34% by mass or less, and more preferably 32% by mass or less. If the content of component (A3) is higher than this range, component (A3) may not be encapsulated in the membrane of the lipid membrane structure.

[0029] The preparation of the emulsifier composition when component (A) contains component (A3) can be carried out in the same manner as when component (A) consists of components (A1) and (A2). In addition, when component (A) contains component (A3), an oil-in-water emulsion composition can be produced in the same manner as when component (A) consists of components (A1) and (A2).

[0030] The oil-in-water emulsion composition of the present invention can be used as it is as a cosmetic or topical skin preparation, or can be used as a raw material for a cosmetic or topical skin preparation by blending it during production. When the oil-in-water emulsion composition of the present invention is used as a raw material for a cosmetic or topical skin preparation, the blending amount is not particularly limited, but is generally 0.01 to 99% by mass, preferably 0.05 to 90% by mass.

[0031] When the oil-in-water emulsion composition of the present invention is used as a cosmetic or topical skin preparation or as a raw material thereof, it may contain water and additives that are usually blended into cosmetic preparations, as necessary, such as oily bases, moisturizers, texture improvers, surfactants, polymers, thickeners, gelling agents, antioxidants, reducing agents, oxidizing agents, antioxidants, whitening agents, vitamins and their derivatives, plant, animal, or microbial extracts, UV absorbers, antibacterial agents, preservatives, chelating agents, pH adjusters, acids, alkalis, solvents, propellants, antipruritics, keratin exfoliants, dissolving agents, antiperspirants, cooling agents, astringents, enzymes, nucleic acids, anti-inflammatory agents, anti-inflammatory agents, hair growth agents, blood circulation promoters, stimulants, hormones, anti-wrinkle and anti-aging agents, irritation mitigators, cooling agents, warming agents, powders, dyes, colorants, dyes, pigments, fragrances, and the like, to an extent that does not impair the effects of the present invention.

[0032] Examples of oily bases include higher alcohols such as cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, arachyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, selachyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, 2-octyldodecanol, and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, Higher fatty acids such as undecylenic acid, 12-hydroxystearic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids, long-chain α-hydroxy fatty acids, dimer acids, hydrogenated dimer acids, and their aluminum salts, calcium salts, magnesium salts, zinc salts, potassium salts, sodium salts, and other metal soaps, as well as nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin , α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, solid paraffin, and other hydrocarbons; candelilla wax, carnauba wax, rice wax, Japan wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, Fischer-Tropsch wax, polyethylene wax, ethylene-propylene copolymer, and other waxes; coconut oil, palm oil, palm kernel oil, safflower oil, olive oil , castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil, and other vegetable oils and fats; beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle oil, and other animal waxes; whale wax, lanolin, orange raffy oil, and other animal waxes;Lanolin derivatives such as liquid lanolin, reduced lanolin, adsorbed purified lanolin, acetated lanolin, acetated liquid lanolin, hydroxylanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, acetated lanolin alcohol, acetate (cetyl lanoyl) ester; lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin, etc. Phospholipids such as lysophospholipids, phosphatidic acid, cyclic lysophosphatidic acid or its salt, and lysolecithin; phospholipid derivatives such as hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, and partially hydrogenated egg yolk phospholipid; sterols such as cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, phytosterol, and cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonanoate, cholesteryl stearate, Acyl sarcosine alkyl esters such as cholesteryl isostearate, cholesteryl oleate, N-lauroyl-L-glutamic acid di(cholesteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di(cholesteryl / octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl / octyldodecyl), and N-lauroyl sarcosine isopropyl. Sterol esters such as sterol esters of 12-hydroxystearate, cholesteryl macadamiate, phytosteryl macadamiate, phytosteryl sunflower seed oil, phytosteryl isostearate, cholesteryl soft lanolinate, cholesteryl hard lanolinate, cholesteryl long-chain branched fatty acid, and cholesteryl long-chain α-hydroxy fatty acid; lipid complexes such as phospholipid-cholesterol complex and phospholipid-phytosterol complex;Octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl palmitate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl lanolinate, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, hydrogenated castor oil isostearate, Monoalcohol carboxylates such as ethyl oleate, avocado oil fatty acid ethyl, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, isopropyl lanolin fatty acid, methylheptyl laurate, methylheptyl myristate, methylheptyl palmitate, methylheptyl isostearate, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl succinate, and triethyl citrate; oxyacid esters such as cetyl lactate, hydrogenated castor oil monoisostearate, γ-erucalactone, and diisostearyl malate;Glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, caprylic / capric triglyceride, caprylic / capric / myristic / stearic triglyceride, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), glyceryl behenate eicosandioate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl glycol dioctanoate, dicaprylate Neopentyl glycol dioctanoate, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, ditrimethylolpropane isostearate / sebacic acid, pentaerythrityl triethylhexanoate, dipentaerythrityl hydroxystearic acid / stearic acid / rosin acid, diglyceryl diisostearate, polyglyceryl tetraisostearate Polyhydric alcohol fatty acid esters such as polyglyceryl-10 nonaisostearate, polyglyceryl-8 deca(erucic acid / isostearate / ricinoleic acid), diglyceryl oligoester (hexyldecanoic acid / sebacic acid), glycol distearate (ethylene glycol distearate), 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl-1,5-pentanediol dineopentanoate; alkyl ethers such as dicaprylyl ether; diisopropyl dimer dilinoleate, ... -Diisostearyl dimer dilinoleate, di(isostearyl / phytosteryl) dimer dilinoleate, phytosteryl / behenyl dimer dilinoleate, phytosteryl / isostearyl / cetyl / stearyl / behenyl dimer dilinoleate, dimer dilinoleyl diisostearate, dimer dilinoleyl hydrogenated rosin condensate, dimer dilinoleic acid hydrogenated castor oil, hydroxyalkyl dimer dilinoleyl ether and other dimer acid or dimer diol derivatives;Fatty acid alkanolamides such as coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (palmitamide MEA), palmitic acid diethanolamide (palmitamide DEA), coconut oil fatty acid methylethanolamide (cocamide methyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopentasiloxane), phenyl trimethicone, diphenyl dimethicone, phenyl dimethicone, (aminoethyl aminopropyl methicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone Preferred examples of the silicones include corn gum, amino-modified silicones such as aminopropyl dimethicone and amodimethicone, cationic modified silicones, polyether-modified silicones such as dimethicone copolyol, polyglycerin-modified silicones, sugar-modified silicones, carboxylic acid-modified silicones, phosphoric acid-modified silicones, sulfate-modified silicones, alkyl-modified silicones, fatty acid-modified silicones, alkyl ether-modified silicones, amino acid-modified silicones, peptide-modified silicones, fluorine-modified silicones, cationic and polyether-modified silicones, amino and polyether-modified silicones, alkyl and polyether-modified silicones, amidoalkyl-modified silicones, aminoglycol-modified silicones, aminophenyl-modified silicones, and polysiloxane-oxyalkylene copolymers; and fluorine-based oils such as perfluorodecane, perfluorooctane, and perfluoropolyether.

[0033] Moisturizing agents and texture improvers include polyols and their polymers such as glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, and ethylene glycol-propylene glycol copolymers; glycol alkyl ethers such as diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, and diethylene glycol dibutyl ether; water-soluble esters such as polyglyceryl-10 (eicosane diacid / tetradecanedioic acid), polyglyceryl-10 tetradecanedioic acid, and bisethoxydiglycol cyclohexanedicarboxylate; and sugar alkanes such as sorbitol, xylitol, erythritol, mannitol, and maltitol. Alcohols; glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrin, and modified cyclodextrins such as maltosylated and hydroxyalkylated), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycine Sugars and their derivatives, such as cogen, ethyl glucoside, glucosyl ethyl methacrylate polymer or copolymer; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucoitin sulfate, caronin sulfate, keratosulfate, dermatan sulfate; Tremella fuciformis extract, Tremella fuciformis polysaccharide; fructans, such as inulin and levan; fucoidan; tuberose polysaccharide, naturally occurring polysaccharides; organic acids, such as citric acid, tartaric acid, lactic acid, and their salts; urea; 2-pyrrolidone-5-carboxylic acid and its sodium salts, etc.;Amino acids and their salts, such as betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine, γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid, carnitine, carnosine, and creatine; collagen, fish-derived collagen, atelocollagen, gelatin, elastin, collagen hydrolysis peptides, hydrolyzed collagen, hydroxypropylammonium chloride hydrolysis collagen, elastin hydrolysis peptides, keratin hydrolysis peptides, hydrolyzed keratin, conchiolin hydrolysis peptides, hydrolyzed conchiolin, silk protein hydrolysis peptides, hydrolyzed silk, sodium lauroyl hydrolyzed silk, soy protein hydrolysis peptides, small Protein peptides and their derivatives such as wheat proteolysis peptides, hydrolyzed wheat protein, casein hydrolysis peptides, and acylated peptides; acylated peptides such as palmitoyl oligopeptide, palmitoyl pentapeptide, and palmitoyl tetrapeptide; silylated peptides; lactic acid bacteria culture liquid, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycoside, glutathione, albumin, whey; choline chloride, phosphorylcholine; placenta extract, air Preferred examples of the active ingredient include animal and plant extracts such as lastin, collagen, aloe extract, witch hazel water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, rose roe extract, yarrow extract, eucalyptus extract, and melilot extract, and ceramides such as natural ceramides (types 1, 2, 3, 4, 5, and 6), hydroxyceramides, pseudoceramides, sphingoglycolipids, ceramides, and glycoceramide-containing extracts.

[0034] Preferred examples of surfactants include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, and polymer surfactants. There is no particular limitation on the HLB of the surfactant, and surfactants with a low HLB of about 1 to a high HLB of about 20 can be used, and it is also preferable to combine surfactants with low and high HLB. Preferred examples of surfactants include anionic surfactants such as fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate ester salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; polyoxyethylene alkyl sulfate salts such as sodium laureth sulfate and triethanolamine laureth sulfate; acyl N-methyl amino acid salts such as sodium cocoyl methyl taurate, potassium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium lauroyl methyl alanine, sodium lauroyl sarcosine, triethanolamine lauroyl sarcosine, and sodium lauroyl glutamate methyl alanine; sodium cocoyl glutamate, triethanolamine cocoyl glutamate, and sodium lauroyl glutamate. Acyl amino acid salts such as sodium myristoyl glutamate, sodium stearoyl glutamate, palmitoyl aspartic acid ditriethanolamine, cocoyl alanine triethanolamine, and sodium dilauroyl glutamate lysine; polyoxyethylene alkyl ether acetates such as sodium laureth acetate; succinic acid ester salts such as sodium lauroyl monoethanolamide succinate; fatty acid alkanolamide ether carboxylates; acyl lactates; polyoxyethylene fatty amine sulfates; fatty acid alkanolamide sulfates; fatty acid glyceride sulfates such as sodium hydrogenated coconut oil fatty acid glycerin sulfate; alkyl benzene polyoxyethylene sulfates; olefin sulfonates such as sodium α-olefin sulfonate; alkyl sulfosuccinates such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate;alkyl ether sulfosuccinates such as disodium laureth sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate; alkyl benzene sulfonates such as sodium tetradecylbenzene sulfonate, triethanolamine tetradecylbenzene sulfonate; alkyl naphthalene sulfonates; alkane sulfonates; α-sulfofatty acid methyl ester salts; acyl isethionates; alkyl glycidyl ether sulfonates; alkyl sulfoacetates; alkyl ether phosphate salts such as sodium laureth phosphate, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monoolethate; alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphate salts; fatty acid amide ether phosphate salts; phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof; silicones such as carboxylic acid modified silicones, phosphate modified silicones, and sulfate modified silicones. ricone-based anionic surfactants, etc.; nonionic surfactants include polyoxyethylene alkyl ethers with various polyoxyethylene addition numbers, such as laureths (polyoxyethylene lauryl ethers), ceteths (polyoxyethylene cetyl ethers), steareths (polyoxyethylene stearyl ethers), beheneths (polyoxyethylene behenyl ethers), isosteareths (polyoxyethylene isostearyl ethers), and octyldodeceths (polyoxyethylene octyldodecyl ethers); polyoxyethylene alkyl phenyl ethers. esters; castor oil and hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, and polyoxyethylene hydrogenated castor oil maleic acid; polyoxyethylene phytosterols; polyoxyethylene cholesterol; polyoxyethylene cholestanol; polyoxyethylene lanolin; polyoxyethylene reduced lanolin;Polyoxyethylene-polyoxypropylene cetyl ether, polyoxyethylene-polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene-polyoxypropylene monobutyl ether, polyoxyethylene-polyoxypropylene hydrogenated lanolin, polyoxyethylene-polyoxypropylene glycerin ether, etc. Polyoxyethylene-polyoxypropylene alkyl ethers; polyoxyethylene-polyoxypropylene glycol; PPG-9 diglyceryl, etc. ) Glycerin polyoxypropylene glycol; glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl oleate, glyceryl coconut oil fatty acid, glyceryl monocottonseed oil fatty acid, glyceryl monoerucate, glyceryl sesquioleate, glyceryl α,α'-oleate pyroglutamate, glyceryl monostearate malate, and other glycerin fatty acid partial esters; polyglyceryl-2, 3, 4, 5, 6, and 8 stearate , 10, polyglyceryl-6 distearate, 10, polyglyceryl-2 tristearate, polyglyceryl-10 deca stearate, polyglyceryl-2 isostearate, 3, 4, 5, 6, 8, 10, polyglyceryl-2 diisostearate (diglyceryl diisostearate), 3, 10, polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3, No. 4, No. 5, No. 6, No. 8, No. 10, polyglycerin fatty acid esters such as polyglyceryl-6 dioleate, polyglyceryl-2 trioleate, and polyglyceryl-10 decaoleate; ethylene glycol mono fatty acid esters such as ethylene glycol monostearate; propylene glycol mono fatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid esters; sorbitol partial fatty acid esters; maltitol partial fatty acid esters; maltitol ethers;Sorbitan fatty acid esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, and diglycerol sorbitan tetra-2-ethylhexylate; sucrose fatty acid esters such as sucrose laurate, sucrose myristate, sucrose palmitate, sucrose dilaurate, sucrose dimyristate, and sucrose dipalmitate. Partial esters of sugar derivatives such as glyceryl, methyl glucoside fatty acid esters, and trehalose undecylenate; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; glycolipids such as mannosyl erythritol lipid; lanolin alcohol; reduced lanolin; polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene dioleate, and other polyoxyethylene fatty acid mono- and diesters; polyoxyethylene propylene glycol fatty acid esters; polyoxyethylene glycol Polyoxyethylene glycerin fatty acid esters such as polyoxyethylene monooleates such as serine monostearate, polyoxyethylene glycerin monoisostearate, and polyoxyethylene glycerin triisostearate; polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, and polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol fatty acid esters such as polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol pentaoleate, and polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid esters; polyoxyethylene alkyl ether fatty acid esters; polyoxyethylene sorbitol beeswax and other polyoxyethylene animal and vegetable oils and fats; isostearyl glyceryl ether, alkyl glyceryl ethers such as chimyl alcohol, selachyl alcohol, and batyl alcohol; polyhydric alcohol alkyl ethers;Polyoxyethylene alkylamines; tetrapolyoxyethylene-tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponin, surfactin, rhamnolipid, sophorolipid, etc.; polyoxyethylene fatty acid amides; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid Fatty acid alkanolamides such as palmitic acid monoethanolamide (paltamide MEA), palmitic acid diethanolamide (paltamide DEA), coconut oil fatty acid methylethanolamide (cocamide methyl MEA); alkyl dimethylamine oxides such as lauramine oxide, cocamine oxide, stearamine oxide, behenamine oxide; alkyl ethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; polyether modified silicones such as dimethicone copolyol, polysiloxane-oxyalkylene copolymers, polyglycerin modified Silicone-based nonionic surfactants such as silicone and sugar-modified silicone; cationic surfactants include alkyltrimethylammonium chlorides such as behentrimonium chloride, steartrimonium chloride, cetrimonium chloride, and lauryltrimonium chloride; alkyltrimethylammonium bromides such as stearyltrimonium bromide; dialkyldimethylammonium chlorides such as distearyldimonium chloride and dicocodimonium chloride; fatty acid amidoamines and their salts such as stearamidopropyl dimethylamine and stearamidoethyl diethylamine; alkyl ether amines and their salts or quaternary salts such as stearoxypropyl dimethylamine; fatty acid amide-type quaternary ammonium salts such as ethyl sulfate long-chain branched fatty acid (12-31) aminopropyl ethyl dimethyl ammonium and ethyl sulfate lanolin fatty acid aminopropyl ethyl dimethyl ammonium; polyoxyethylene alkylamines and their salts or quaternary salts; alkylamine salts; fatty acid amide guanidinium salts; alkyl ether amine monium salts; alkyl trialkylene glycol ammonium salts; benzalkonium salts;benzethonium salts; pyridinium salts such as cetylpyridinium chloride; imidazolinium salts; alkylisoquinolinium salts; dialkylmorphonium salts; polyamine fatty acid derivatives; silicone-based cationic surfactants such as amino-modified silicones such as aminopropyl dimethicone and amodimethicone, cation-modified silicones, cation-modified and polyether-modified silicones, and amino-modified and polyether-modified silicones; amphoteric surfactants include N-alkyl-N,N-dimethyl amino acid betaines such as lauryl betaine (lauryl dimethyl amino acetate betaine); fatty acid amidoalkyl-N,N-dimethyl amino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; betaines such as alkyldimethyltaurine; sulfate type betaines such as alkyldimethylaminoethanol sulfate ester; phosphate type betaines such as alkyldimethylaminoethanol phosphate ester; sphingophospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin, phospholipids such as lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, and hydroxide lecithin; silicone-based amphoteric surfactants, etc.; and among the polymer surfactants, preferred examples include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, and acrylic acid / alkyl methacrylate copolymers; and various silicone-based surfactants.

[0035] Polymers, thickeners, and gelling agents include guar gum, locust bean gum, queen seed, carrageenan, galactan, gum arabic, tara gum, tamarind, furcellan, karaya gum, aoi, caragam, tragacanth gum, pectin, pectinic acid and its salts, alginic acid and its salts, mannan; starches such as rice, corn, potato, and wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin, chitosan, etc. cellulose, agar, cassou extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose and its sodium salts, methylhydroxypropylcellulose, carboxylated cellulose nanofiber, carboxymethylcellulose nanofiber, phosphated cellulose nanofiber, sulfonated cellulose nanofiber, sodium cellulose sulfate, dialkyldimethylammonium sulfate cellulose and its derivatives such as cellulose acetate, crystalline cellulose, cellulose powder; starch-based polymers such as soluble starch, carboxymethyl starch, methyl hydroxypropyl starch, methyl starch, starch derivatives such as hydroxypropyltrimonium starch chloride, corn starch aluminum octenyl succinate; alginic acid derivatives such as sodium alginate and propylene glycol alginate; polyvinylpyrrolidone (PVP), polyvinyl alcohol (PVA), vinylpyrrolidone-vinyl alcohol copolymer, polyvinyl methyl ether; polyethylene glycol, polypropylene glycol, polyoxyethylene-polyoxypropylene copolymer; amphoteric methacrylate copolymers such as (methacryloyloxyethyl carboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine oxide methacrylate) copolymer; (dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP;Partially saponified polyvinyl acetate, maleic acid copolymer; vinylpyrrolidone-dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; polyacrylamide; polyacrylic acid ester copolymers such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its sodium salt, acrylic acid-methacrylic acid ester copolymer; acrylic acid-alkyl methacrylate copolymer; cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride-acrylamide copolymer such as polyquaternium-7, acrylic acid-diallyldimethylammonium chloride copolymer such as polyquaternium-22, acrylic acid-diallyldimethylammonium chloride-acrylamide copolymer such as polyquaternium-39, acrylic acid-cationized methacrylic acid ester copolymer, acrylic acid-cationized methacrylic acid amide copolymer, acrylic acid-cationized methacrylic acid amide copolymer, acrylic acid-47 ... copolymer of methacrylic acid, methyl acrylate, methacrylamidopropyltrimethylammonium chloride, polymer of choline ester of methacrylic acid chloride; cationic oligosaccharides, cationic dextran, cationic polysaccharides such as guar hydroxypropyltrimonium chloride; polyethyleneimine; cationic polymers; polymers of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and copolymers with butyl methacrylate copolymers; acrylic resin emulsions, polyethyl acrylate emulsions, polyacrylic alkyl ester emulsions, polyvinyl acetate resin emulsions, natural rubber latex, synthetic latex and other polymer emulsions; nitrocellulose; polyurethanes and various copolymers; various silicones; various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluorine-based polymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate;Preferred examples include anhydrous silicic acid, fumed silica (ultrafine particle anhydrous silicic acid), aluminum magnesium silicate, sodium magnesium silicate, metal soap, dialkyl phosphate metal salt, bentonite, hectorite, organically modified clay minerals, sucrose fatty acid esters, and fructooligosaccharide fatty acid esters.

[0036] The antioxidants preferably include tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or its derivatives; erythorbic acid and its derivatives; sulfites such as sodium sulfite; hydrogen sulfites such as sodium hydrogen sulfite; thiosulfates such as sodium thiosulfate; metabisulfites; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, and cysteine ​​hydrochloride. The reducing agents preferably include thioglycolic acid, cysteine, and cysteamine. The oxidizing agents preferably include hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate. Examples of antioxidants include ascorbic acid, ascorbic acid phosphate salts such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate; ascorbic acid fatty acid esters such as monostearate ascorbic acid, monopalmitate ascorbic acid, dipalmitate ascorbic acid, and tetraisopalmitate ascorbic acid; ascorbic acid ethers such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid; ascorbic acid glucoside and its fatty acid esters such as ascorbic acid-2-glucoside; Preferred examples of the vitamin A derivatives include ascorbic acid derivatives such as tocopheryl ascorbyl phosphate and tocopheryl ascorbyl phosphate; vitamin A derivatives such as retinol, retinol acetate, retinol palmitate, and hydrogenated retinol; vitamin E derivatives such as tocopherol, tocopherol acetate, and tocotrienol; carotenoids such as carotene, lycopene, astaxanthin, and lutein; polyphenols such as phlorotannin, curcumin, anthocyanin, proanthocyanin, catechin, ellagic acid, quercetin, and apple polyphenol; coenzyme Q10, lipoic acid, lactoferrin, sesamin, hesperidin, protoanthocyanidin, lignan, chlorogenic acid, rutin, fullerene, and platinum nanocolloid.

[0037] Examples of the whitening agent include hydroquinone glycosides and esters thereof, such as arbutin and α-arbutin; ascorbic acid, ascorbic acid phosphate salts, such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate; ascorbic acid fatty acid esters, such as ascorbic acid monostearate, ascorbic acid monopalmitate, ascorbic acid dipalmitate, and ascorbic acid tetraisopalmitate; ascorbic acid esters, such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid; ascorbic acid glucoside and its fatty acid esters, such as ascorbic acid sulfate and tocopheryl ascorbyl phosphate; tranexamic acid derivatives, such as tranexamic acid, cetyl tranexamate, and tranexamic acid amide; licorice extract-related substances, such as glabridin, glabrene, liquiritin, and isoliquiritin; and plant extracts, such as kojic acid, ellagic acid, ferulic acid and their derivatives, placenta extract, glutathione, oryzanol, butylresorcinol, oil-soluble chamomilla extract, oil-soluble licorice extract, Nishikawa willow extract, and saxifrage extract, are preferred.

[0038] Vitamins and their derivatives include vitamin A such as retinol, retinol acetate, and retinol palmitate; vitamin B such as thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, flavin adenine dinucleotide, cyanocobalamin, folic acids, nicotinic acids such as nicotinamide and benzyl nicotinate, and choline; vitamin C such as ascorbic acid and its sodium salts; vitamin D; vitamin E such as α-, β-, γ-, and δ-tocopherol; other vitamins such as pantothenic acid and biotin; and vitamin B such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate. Preferred examples of the compound include ascorbic acid phosphate salts, ascorbic acid fatty acid esters such as ascorbic acid tetraisopalmitate, ascorbyl stearate, ascorbyl palmitate, ascorbyl dipalmitate, etc., ascorbic acid alkyl ethers such as ascorbic acid ethyl ether, ascorbic acid glucoside and its fatty acid esters such as ascorbic acid-2-glucoside, and ascorbic acid derivatives such as tocopheryl ascorbyl phosphate; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol linoleate, tocopherol ferulate, tocopherol phosphate, etc., tocotrienol, and various other vitamin derivatives.

[0039] Plant, animal and microbial extracts include iris extract, angelica extract, asparagus extract, avocado extract, amacha extract, almond extract, althea extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, ginkgo extract, inchiko extract, fennel extract, turmeric extract, oolong tea extract, uva-ursi extract, angelica extract, echinacea leaf extract, enmeiso extract, scutellaria extract, phellodendron bark extract, coptis extract, barley extract, ginseng extract, hypericum extract, and nettle extract. Sow extract, Ononis extract, Dutch mustard extract, Orange extract, Seawater dried product, Seaweed extract, Oyster leaf extract, Kakyoku extract, Hydrolyzed elastin, Hydrolyzed wheat powder, Hydrolyzed silk, Pueraria root extract, Chamomilla extract, Oil-soluble Chamomilla extract, Carrot extract, Artemisia capillaris extract, Oat extract, Karkade extract, Licorice extract, Oil-soluble Licorice extract, Kiwi extract, Kiou extract, Jew's ear extract, Cinchona extract, Cucumber extract, Paulownia leaf extract, Guanosine, Guava extract, Sophora root extract, Gardenia extract, Sasa veitchii extract, Sophora flavonoides extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar extract, chlorella extract, mulberry extract, gentiana extract, geranium extract, black tea extract, yeast extract, magnolia bark extract, coffee extract, burdock extract, rice extract, fermented rice extract, fermented rice bran extract, rice germ oil, comfrey extract, collagen, cowberry extract, Chinese laurel extract, bupleurum extract, umbilical cord extract, umbilical cord extract, saffron extract, salvia extract, soapwort extract, bamboo grass extract, hawthorn extract, sanschae Japanese flounder, Japanese pepper extract, shiitake mushroom extract, rehmannia extract, lithospermum extract, perilla extract, linden extract, meadowsweet extract, jatoba extract, peony extract, angelica extract, calamus root extract, white birch extract, white wood ear extract, horsetail extract, stevia extract, stevia fermentation product, Nishikawa willow extract, ivy extract, hawthorn extract, elderberry extract, yarrow extract, peppermint extract, sage extract, mallow extract, cnidium rhizome extract, swertia britannica extract, sophora japonica extract, rhubarb extract,Soybean extract, Chinese laurel extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, Imperata cylindrica extract, tangerine extract, tea tree oil, sweet tea extract, chili pepper extract, angelica extract, calendula extract, toad extract, spruce extract, dokudami extract, tomato extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, burdock extract, lotus extract, parsley extract, birch extract, honey, witch hazel extract, parietaria extract, yarrow extract, bisabolol, cypress extract, bifidobacteria extract, loquat extract, coltsfoot extract, butterbur bud extract, bupleurum extract, butcher's broom extract, grape extract, grape seed extract Preferred examples of the extract include whiting, propolis, loofah extract, safflower extract, peppermint extract, linden extract, peony extract, hop extract, squid extract, pine extract, horse chestnut extract, skunk cabbage extract, soapberry extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, saxifrage extract, yuzu extract, lily extract, coix seed extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, lychee extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, Roman chamomile extract, royal jelly extract, and burnet extract.

[0040] Examples of ultraviolet absorbents include benzoic acid-based ultraviolet absorbents such as para-aminobenzoic acid, para-aminobenzoic acid monoglycerin ester, N,N-dipropoxy para-aminobenzoic acid ethyl ester, N,N-diethoxy para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid butyl ester, and N,N-dimethyl para-aminobenzoic acid ethyl ester; anthranilic acid-based ultraviolet absorbents such as homomenthyl-N-acetylanthranilate; salicylic acid-based ultraviolet absorbents such as salicylic acid and its sodium salt, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and p-isopropanol phenyl salicylate; octyl cinnamate, Cinnamic acid-based ultraviolet absorbers such as ethyl-4-isopropylcinnamate, methyl-2,5-diisopropylcinnamate, ethyl-2,4-diisopropylcinnamate, methyl-2,4-diisopropylcinnamate, propyl-p-methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, 2-ethylhexyl-p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (cinoxate), cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate (octocurin), glyceryl mono-2-ethylhexanoyl-di-paramethoxycinnamate, ferulic acid and its derivatives;Benzophenone UV absorbers such as 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, and 4-hydroxy-3-carboxybenzophenone; 3-(4'-methylbenzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylbenzotriazole; 2-(2'-hydro 2-(2'-hydroxy-5'-methylphenylbenzotriazole;Dibenzalazine;Dianisoylmethane;5-(3,3-dimethyl-2-norbornylidene)-3-pentan-2-one;Dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane;Octyltriazone;Urocanic acid and ethyl urocanate derivatives; ... Preferred examples thereof include hydantoin derivatives such as 1-(3,4-dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, dimethoxybenzylidene dioxoimidazolidinepropionate 2-ethylhexyl, phenylbenzimidazolazole sulfonic acid, terephthalidenedicamphor sulfonic acid, drometrizole trisiloxane, methyl anthranilate, rutin and its derivatives, and oryzanol and its derivatives.

[0041] Antibacterial and preservative agents include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, and butylparaben; phenoxyethanol; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol; alkyl glyceryl ethers such as 2-ethylhexylglyceryl ether (ethylhexylglycerin); salicylic acid; lanolin fatty acids and their salts; sodium benzoate; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazolinium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, and quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, and benzalkonium chloride. Preferred examples of the antibacterial agent include phenyl ether, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, and hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, and sodium phenylphenol; phenylethyl alcohol, photosensitizers, antibacterial zeolites, and silver ions. However, when used as an antibacterial agent or preservative for the purpose of preservation, it is more preferable to use phenoxyethanol; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol; and alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether, from the viewpoint of safety of the cosmetic or topical skin preparation.

[0042] Preferred examples of the chelating agent include edetates (ethylenediaminetetraacetates) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetates such as HEDTA3Na; pentetates (diethylenetriaminepentaacetate); phytic acid; phosphonic acids such as etidronic acid and salts thereof such as their sodium salts; sodium oxalate; polyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine, gluconic acid, ascorbic acid, succinic acid, and tartaric acid.

[0043] Preferred examples of the pH adjuster, acid, or alkali include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanolamine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, sodium hydroxide, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate.

[0044] Solvents and propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol, and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, and isopentyl diol; diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, and diethylene glycol diethyl ether. Preferred examples of the propellant include glycol ethers such as propylene glycol monoethyl ether; glycol ether esters such as ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate, and propylene glycol monoethyl ether acetate; glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate, acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbons, next-generation fluorocarbons; LPG, dimethyl ether, and carbon dioxide gas.

[0045] Examples of antipruritic agents include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, and substance-P inhibitors. Examples of keratin peeling and dissolving agents include salicylic acid, sulfur, resorcin, selenium sulfide, pyridoxine, and glycolic acid. Examples of antiperspirants include aluminum chlorohydrate, aluminum chloride, zinc oxide, and zinc paraphenolsulfonate. Examples of cooling agents include menthol and methyl salicylate. Examples of astringents include citric acid, tartaric acid, lactic acid, aluminum potassium sulfate, tannic acid, and caffeine. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, and protease. Examples of nucleic acids include ribonucleic acid and its salts, deoxyribonucleic acid and its salts, and adenosine triphosphate disodium.

[0046] Preferred examples of the anti-inflammatory agent include glycyrrhizinic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid and its derivatives, azelaic acid and its derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, chlorpheniramine maleate; and plant extracts such as peach leaf extract and mugwort leaf extract. Preferred examples of hair growth agents, blood circulation promoters, and stimulants include plant extracts and tinctures such as Swertia japonica extract, Capsicum tincture, Ginger tincture, Ginger extract, and Cantharis tincture; capsaicin, nonylic acid valenylamide, zingerone, ichthammol, tannic acid, borneol, cyclandelate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthine, γ-oryzanol, cepharanthine, vitamin E, and derivatives such as tocopherol nicotinate and tocopherol acetate, γ-oryzanol, nicotinic acid, and derivatives such as nicotinamide, nicotinic acid benzyl ester, inositol hexanicotinate, and nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, flavanonol derivatives, stigmasterol or stigmastanol and its glycosides, and minoxidil. Preferred examples of hormones include estradiol, estrone, ethinylestradiol, cortisone, hydrocortisone, and prednisone.

[0047] Anti-wrinkle and anti-aging agents include ascorbic acid, ascorbic acid phosphate salts such as sodium ascorbic acid phosphate and magnesium ascorbic acid phosphate; ascorbic acid fatty acid esters such as ascorbic acid monostearate, ascorbic acid monopalmitate, ascorbic acid dipalmitate, and ascorbic acid tetraisopalmitate; ascorbic acid ethers such as 3-O-ethyl ascorbic acid, 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, and hexylglyceryl ascorbic acid; ascorbic acid glucoside and its fatty acid esters such as ascorbic acid 2-glucoside; and ascorbic acid derivatives such as ascorbic acid sulfate and tocopheryl ascorbyl phosphate. Preferred examples of the vitamin A derivatives include retinol, retinol acetate, retinol palmitate, and hydrogenated retinol; nicotinamide, glutathione, cysteine, crocetin, sericin, geraniol, glycerin glucoside, lactoferrin, proanthocyanin, pantothenic acid, panthenol, soybean saponin, revelastrol, isoflavone, coenzyme Q10, chondroitin sulfate, acetylglucosamine, glycerophosphatidylcholine, hydrolyzed hyaluronic acid, collagen peptide, conchiolin hydrolyzate, adenosine 5'-monophosphate, phosphatidylinositol, trifluoroisopropyloxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetic acid Na, and tranexamic acid and derivatives thereof.

[0048] Preferred examples of the irritation alleviating agent include mannosylerythritol lipid, dimer dilinoleic acid diethylene glycol oligomer ester, diisostearyl malate, N-acyl-L-glutamic acid, trehalose mono fatty acid ester, fatty acid amidoamine oxide, alkyldimethylamine oxide, phenylethyl glucoside, lauryl glucoside, ferulic acid glucoside, salicin, cedrol, polyethylene glycol, polypropylene glycol, etc. Preferred examples of the cooling agent include menthol, camphor, menthyl lactate, monomenthyl succinate, menthyl acetate, borneol, cineol, thymol, peppermint oil, peppermint oil, and derivatives thereof. Preferred examples of the warming agent include vanillin and its derivatives, nonanoic acid vanillylamide, shogaol, gingerol, capsicum tincture, capsicum extract, nicotinic acid derivatives such as benzyl nicotinate, methyl nicotinate, phenyl nicotinate, and tocopherol nicotinate, capsaicin, watercress extract, Japanese pepper extract, ginger extract, and canthari extract.

[0049] Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, tungstate metal salts, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, metal soap (e.g. zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine, Prussian blue, carbon black, titanium oxide, fine and ultrafine titanium oxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silicic anhydride), titanium mica. Preferred examples of the inorganic powders include inorganic powders of various sizes and shapes, such as fish scale foil, boron nitride, photochromic pigments, synthetic fluorine-containing mica, fine particle composite powders, gold, and aluminum, and inorganic powders which have been treated with silicones such as hydrogen silicone and cyclic hydrogen silicone, or other silanes, or various surface treatment agents such as titanium coupling agents to make them hydrophobic or hydrophilic; organic powders of various sizes and shapes, such as starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, polyester powder, benzoguanamine resin powder, polyethylene terephthalate-polymethyl methacrylate laminate powder, polyethylene terephthalate-aluminum-epoxy laminate powder, urethane powder, silicone powder, Teflon (registered trademark) powder, and surface-treated powders; and organic-inorganic composite powders.Preferred examples of the inorganic salts include sodium chloride-containing salts such as table salt, ordinary salt, rock salt, sea salt, and natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, aluminum / potassium sulfate (alum), aluminum / ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, ferrous sulfate, and copper sulfate; and sodium phosphates such as 1Na / 2Na / 3Na phosphate, potassium phosphates, calcium phosphates, and magnesium phosphates.

[0050] Dyes, colorants, dyes and pigments include Brown No. 201, Black No. 401, Purple No. 201, Purple No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 202, Blue No. 203, Blue No. 204, Blue No. 205, Blue No. 403, Blue No. 404, Green No. 3, Green No. 201, Green No. 202, Green No. 204, Green No. 205, Green No. 3, Green No. 401, Green No. 402 No., Red No. 102, Red No. 104-1, Red No. 105-1, Red No. 106, Red No. 2, Red No. 3, Red No. 201, Red No. 202, Red No. 203, Red No. 204, Red No. 205, Red No. 206, Red No. 207, Red No. 208, Red No. 213, Red No. 214, Red No. 215, Red No. 218, Red No. 219, Red No. 220, Red No. 221, Red No. 223 , Red No. 225, Red No. 226, Red No. 227, Red No. 228, Red No. 230-1, Red No. 230-2, Red No. 231, Red No. 232, Red No. 3, Red No. 401, Red No. 40 No. 4, Red No. 405, Red No. 501, Red No. 502, Red No. 503, Red No. 504, Red No. 505, Red No. 506, Orange No. 201, Orange No. 203, Orange No. 204, Orange 20 Legal dyes such as No. 5, Orange 206, Orange 207, Orange 401, Orange 402, Orange 403, Yellow 201, Yellow 202-1, Yellow 202-2, Yellow 203, Yellow 204, Yellow 205, Yellow 4, Yellow 401, Yellow 402, Yellow 403-1, Yellow 404, Yellow 405, Yellow 406, Yellow 407, Yellow 5, etc.; Acid Other acid dyes such as Red 14; basic dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, Arianor Straw Yellow; nitro dyes such as HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydroxypropylamino-3-nitrophenol, N,N'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine, HC Blue 2, Basic Blue 26; disperse dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (red iron oxide) and iron titanate; inorganic brown pigments such as gamma-iron oxide; inorganic yellow pigments such as yellow iron oxide and ochre; inorganic black pigments such as black iron oxide and low-order titanium oxide;Inorganic purple pigments such as mango violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide, and cobalt titanate; inorganic blue pigments such as ultramarine and Prussian blue; pearl pigments such as titanium dioxide coated mica, titanium dioxide coated bismuth oxychloride, titanium dioxide coated talc, colored titanium dioxide coated mica, bismuth oxychloride, and fish scale foil; metal powder pigments such as aluminum powder, copper powder, and gold; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, carthamine, and quercetin. Preferred examples of such dyes include naphthoquinones such as tin, crocin, chlorophyll, curcumin, cochineal, and shikonin, bixin, flavones, betacyanidin, henna, hemoglobin, lycopene, riboflavin, and rutin; oxidation dye intermediates and couplers such as p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylenediamine, 5-amino-2-methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine, and salts thereof; autoxidation dyes such as indoline; and dihydroxyacetone.

[0051] Fragrances include acetyl cedrene, amyl cinnamaldehyde, allyl amyl glycolate, β-ionone, isoe-super, isobutylquinoline, iris oil, iron, indole, ylang-ylang oil, undecanal, undecenal, γ-undecalactone, estragole, eugenol, oakmoss, opoponax resinoid, orange oil, eugenol, aurantiol, galacsolid, carvacrol, L-carvone, camphor, canon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile, isobornyl acetate, geranyl acetate, dimethylbenzylcarbinyl acetate, styralyl acetate, cedryl acetate, terpinel acetate, pt-butylcyclohexyl acetate. , vetiveryl acetate, benzyl acetate, linalyl acetate, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamen aldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrcenol, jasmine absolute, jasmine lactone, cis-jasmone, citral, citronenol, citronellal, cinnamon bark oil, 1,8-cineole, cinnamaldehyde, styrax resinoids, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascone, damascenone, thymol, tuberose absolute, decanal, decalactone, terpineol, gamma-terpinene, triplal, nerol, nonanal, 2,6-Nonadienol, Nonalactone, Patchouli Alcohol, Vanilla Absolute, Vanillin, Basil Oil, Patchouli Oil, Hydroxycitronellal, Alpha-Pinene, Piperitone, Phenethyl Alcohol, Phenylacetaldehyde, Petitgrain Oil, Hexylcinnamaldehyde, cis-3-Hexenol, Balsam of Peru, Vetiver Oil, Vetiverol, Peppermint Oil, Pepper Oil, Heliotropin, Bergamot Oil, Benzyl Benzene Preferred examples of the synthetic and natural fragrances include maltitol, borneol, myrrhizinoid, musk ketone, methylnonylacetaldehyde, γ-methylionone, menthol, L-menthol, L-menthone, eucalyptus oil, β-ionone, lime oil, lavender oil, D-limonene, linalool, lyral, lilial, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, and various essential oils, as well as various blended fragrances.

[0052] Preferred examples of water include ordinary water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionized water, and cluster water.

[0053] In addition to the above, it is possible to contain known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc. in known combinations, ratios, and amounts, such as ingredients listed in the Cosmetic Raw Materials Standards, Cosmetic Type Ingredient Standards, Japan Cosmetic Industry Association Ingredient Labeling Name List, INCI Dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Quasi-drug Raw Materials Standards, Japanese Pharmacopoeia, Pharmaceutical Additives Standards, Food Additives Official Compendium, etc., and ingredients listed in Japanese and foreign patent gazettes and patent publications (including published gazettes and republications) that belong to the International Patent Classification IPC classifications A61K7 and A61K8.

[0054] The types of the cosmetic of the present invention include hair cosmetics, skin cosmetics, make-up cosmetics, fragrance cosmetics, body cosmetics, etc. The cosmetic of the present invention can be produced according to a conventional method.

[0055] To explain the types of cosmetics of the present invention in more detail, preferred examples of hair cosmetics include shampoos such as oil shampoo, cream shampoo, conditioning shampoo, anti-dandruff shampoo, hair color shampoo, and rinse-integrated shampoo; hair care agents such as rinse, conditioner, treatment, hair pack, leave-on treatment, hair mist, and hair oil; hair styling products such as hair foam, hair mousse, hair spray, hair wax, hair gel, hair cream, water grease, setting lotion, pomade, and hair styling products; hair dyes such as color lotions, hair color treatments, hair manicures, and oxidation hair dyes; hair tonics, hair liquids, hair blow dryers, split end coats, permanent wave agents, straight perm agents, hair bleach, hair color pre-treatments, hair color after-treatments, perm pre-treatments, perm after-treatments, and hair growth agents.

[0056] Skin cosmetics include lotions such as softening lotion, astringent lotion, cleansing lotion, multi-layered lotion, and liposome lotion; emulsions such as emollient lotion, moisture lotion, milky lotion, nourishing lotion, nourishing milk, skin moisture, moisturizing emulsion, massage lotion, exfoliating smoother, elbow lotion, hand lotion, and body lotion; emollient cream, nourishing cream, nourishing cream, vanishing cream, moisture cream, night cream, massage cream, cleansing cream, makeup cream, base cream, pre-makeup cream, sunscreen cream, suntan cream, hair removal cream, deodorant cream, shaving cream, keratin cream, etc. Preferred examples of the cosmetic products include skin care cosmetics such as creams such as softening cream, gels such as moisturizing gel, whitening gel, all-in-one gel, and beauty serums such as moisturizing essence, whitening essence, moisturizing serum, and whitening serum; sunscreen cosmetics such as sun protect, sun protector, UV care milk, and sunscreen; packs and masks such as peel-off pack, powder pack, washing pack, oil pack, and cleansing mask; cleansing cosmetics such as cleansing foam, cleansing cream, cleansing milk, cleansing lotion, cleansing gel, and cleansing oil; and facial cleansers such as paste facial foam, gel facial foam, foam facial foam, facial cleansing powder, cosmetic soap, transparent soap, medicated soap, liquid soap, and shaving soap.

[0057] Preferred examples of makeup cosmetics include lipstick, lip gloss, foundation, blush, face powder, concealer, eyeliner, mascara, eye shadow, eyebrow pencil, nail enamel, enamel remover, and nail treatment.

[0058] Preferred examples of the aromatic cosmetic include perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, perfume paste, aromatic powder, perfumed soap, body lotion, and bath oil.

[0059] Preferred examples of body cosmetics include body cleansers such as body shampoos, deodorant cosmetics such as deodorant lotions, deodorant powders, deodorant sprays and deodorant sticks, bleaches, depilatories, bath additives, and insect repellents such as insect repellent sprays.

[0060] Preferred types of the skin external preparation of the present invention include ointments, lotions, creams or gels for the skin, patches, liniments, liquid coatings, etc. They can also be used as oral cosmetic products such as toothpastes and mouthwashes.

[0061] Preferred dosage forms of the cosmetic or topical skin preparation of the present invention include emulsion-type cosmetics such as oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, and O / W / O type, oil-based cosmetics, solid cosmetics, liquid cosmetics, paste cosmetics, stick-type cosmetics, volatile oil-type cosmetics, powder cosmetics, jelly-type cosmetics, gel-type cosmetics, paste-type cosmetics, emulsified polymer-type cosmetics, sheet-type cosmetics, mist-type cosmetics, and spray-type cosmetics.

[0062] The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to these examples in any way.

[0063] Emulsifier compositions of the present invention (Examples 1 to 20) and comparative emulsifier compositions (Comparative Examples 1 to 6) were prepared according to the compositions shown in Tables 1 to 4. <Method for preparing emulsifier composition> Without component (C) Each component of component (A) was added without stirring to component (B) in which phenoxyethanol had been dissolved beforehand, and the mixture was stirred with a homomixer (50°C, 5000 rpm, 5 minutes) and cooled. Ingredient (C) included Components (A) and (C) were mixed with stirring at 70° C. to prepare a polyhydric alcohol liquid. The resulting polyhydric alcohol liquid was added to component (B) in which phenoxyethanol had been dissolved, while stirring, and the mixture was stirred with a homomixer (50° C., 5000 rpm, 5 minutes) and cooled.

[0064] [Table 1]

[0065] [Table 2]

[0066] [Table 3]

[0067] [Table 4]

[0068] Using the emulsifier compositions of Examples 1 to 20 and the emulsifier compositions of Comparative Examples 1 to 6 obtained above, oil-in-water emulsion compositions were produced according to the compositions shown in Tables 5 to 11. The emulsified state of the obtained oil-in-water emulsion compositions was visually confirmed, and the emulsifying ability of the emulsifier compositions was evaluated. The evaluation results of the emulsifying ability are shown in the lower part of the table. <Method of producing oil-in-water emulsion composition> The oily component was added to the emulsifier composition or to a mixture of the emulsifier composition and purified water that had been previously stirred and mixed, and then stirred and mixed with a homomixer (room temperature, 5000 rpm, 5 minutes).The oily component used was ethylhexyl palmitate, a polar oil, squalane, a non-polar oil, or dimethicone 50cs, a silicone oil. <Method for evaluating emulsifying ability> The emulsified state of the resulting oil-in-water emulsion composition was visually observed and evaluated according to the following criteria. ○ Uniform emulsion state ×: Inhomogeneous emulsion state (separation, oil floating, etc.)

[0069] [Table 5]

[0070] [Table 6]

[0071] [Table 7]

[0072] [Table 8]

[0073] [Table 9]

[0074] [Table 10]

[0075] [Table 11]

[0076] From the results of Tables 5 to 8, it was confirmed that the emulsifier composition of the present invention can prepare an oil-in-water emulsion composition by stirring and mixing with an oily component at room temperature without heating. Therefore, it was found that the emulsifier composition of the present invention can be used as an emulsifier for an oil-in-water emulsion composition. In addition, from the results of Table 9, it was confirmed that the emulsifier composition of the present invention can be used as an emulsifier for an oil-in-water emulsion composition regardless of the polarity of the oily component. In addition, from the results of Tables 10 to 11, it was found that when polyglyceryl-10 myristate was used as component (A1), it was possible to emulsify an oily component up to 50 times by mass of the content of component (A), and when sucrose myristate was used as component (A1), it was possible to emulsify an oily component up to 30 times by mass of the content of component (A).

[0077] Below, examples of cosmetic formulations using the technology of the present invention are described.

[0078] Formulation example 1: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.5 Polyglyceryl-10 Myristate 0.5 Purified water (total amount is 100) Part B Triethylhexanoin 5.0 Neosolue-DiSM (Nippon Fine Chemicals) 1.0 Plandool-LG2 (Nippon Fine Chemicals) 1.0 Plandool-H (Nippon Fine Chemical) 0.2 Plandool-MAS (Nippon Fine Chemicals) 0.2 C part Purified water 20.0 Tranexamic acid (Nippon Fine Chemicals) 2.0 Nicotinamide 5.0 Phytic acid 0.3 Neosolue-Aqulio (Nippon Fine Chemicals) 0.5 Sodium hyaluronate 0.01 Carbomer 0.01 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0079] Formulation example 2: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.2 Sucrose myristate 0.8 Glycerin 6.0 BG 3.0 Purified water (total amount is 100) Part B Squalane 10.0 Plandool-ISS (Nippon Fine Chemical) 1.0 Macadamia nut oil 1.0 Hydrogenated rapeseed oil alcohol 1.0 Olive oil fatty acid cetearyl 1.0 Sorbitan olivate 0.8 Polyglyceryl-10 Oleate 1.0 Acrylic acid / alkyl methacrylate copolymer (2% aqueous solution) 5.0 (Ammonium acryloyldimethyltaurate / Beheneth-25) methacrylate crosspolymer (2% aqueous solution) 10.0 Tremoist-SL (Nippon Fine Chemicals) 1.0 C part Purified water 20.0 Hydrolyzed polygamma-glutamic acid K 0.1 Sodium polyglutamate 0.1 Oligopeptide-24 0.05 Phenoxyethanol 0.5 Potassium hydroxide 0.1 -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0080] Formulation example 3: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.3 Polyglyceryl-10 Palmitate 0.7 Purified water (total amount is 100) Part B Ethylhexyl palmitate (Nippon Fine Chemicals) 7.0 Squalane 2.0 Carbomer (2% aqueous solution) 10.0 C part Purified water 5.0 Potassium hydroxide 0.1 Neosolue-Aqulio (Nippon Fine Chemicals) 1.0 Glucosylceramide 0.5 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0081] Formulation example 4: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.7 Polyglyceryl-10 Laurate 0.2 Purified water (total amount is 100) Part B Triethylhexanoin 7.0 LUSPLAN SR-DM4 (Nippon Fine Chemicals) 0.5 Hydrogenated polyisobutene 0.5 Isododecane 1.5 Cetostearyl alcohol 1.0 Arachyl alcohol 0.1 Jojoba Alcohol 3.0 Chiral alcohol 0.3 Selachyl alcohol 0.1 Hexyldecanol 0.5 C part Purified water 20.0 Carbomer (2% aqueous solution) 10.0 Xanthan gum 0.1 Neosolue-AquaS (Nippon Fine Chemical) 0.5 Polyquaternium-51 1.0 Tranexamic acid (Nippon Fine Chemicals) 2.0 Nicotinamide 5.0 Methylparaben 0.15 -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0082] Formulation example 5: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.1 Sucrose laurate 0.9 Purified water (total amount is 100) Part B Ethylhexyl palmitate (Nippon Fine Chemicals) 7.0 Squalane 2.0 Carbomer (2% aqueous solution) 10.0 C part Purified water 5.0 Potassium hydroxide 0.1 Tremoist-SL (Nippon Fine Chemicals) 0.1 Sodium hyaluronate 0.01 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0083] Formulation example 6: Emulsion Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Polyglyceryl-10 Dimyristate 1.0 Ceramide 1 0.01 Ceramide 2 0.01 Ceramide 3 0.01 Ceramide 4 0.01 Ceramide 5 0.01 Ceramide 6 0.01 1,2-Hexanediol 10.0 BG 15.0 Part B Purified water (total amount is 100) C part Diethylhexyl succinate (Nippon Fine Chemicals) 5.0 LUSPLAN PI-DA (Nippon Fine Chemical) 1.0 Plandool-G (Nippon Fine Chemical) 0.1 Plandool-LG1 (Nippon Fine Chemicals) 0.1 Plandool-SUN (Nippon Fine Chemical) 0.1 D part 3-O-Ethyl ascorbic acid (Nippon Fine Chemicals) 1.0 Tranexamic acid (Nippon Fine Chemicals) 1.0 Inulin-SC (Nippon Fine Chemical) 1.0 Glycyrrhizic acid 2K 0.05 Tremoist-TP (Nippon Fine Chemical) 0.01 Xanthan gum 0.05 Phenoxyethanol 0.2 Methylparaben 0.15 Citric acid 0.1 Sodium citrate 0.2 -------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0084] Formulation Example 7: Emulsion Component Amount (wt%) -------------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 10.0 Lysolecithin (Nippon Fine Chemicals) 0.1 Part B Squalane 4.0 Caprylic / capric triglyceride (Nippon Fine Chemicals) 4.0 α-Olefin Oligomer 2.5 Dimethicone 5cs 3.5 Cetanol 1.5 Glyceryl stearate 1.0 C part Hydroxyproline 0.05 Citric acid 0.01 Sodium citrate 0.09 Arbutin (Nippon Fine Chemicals) 3.0 Phenoxyethanol 0.3 Methylparaben 0.1 Acrylic acid / alkyl methacrylate copolymer 0.1 Potassium hydroxide 0.1 Purified water (total amount is 100) D part Oil-in-water emulsion composition of Example 24 30.0 ----------------------------------- (Preparation method) Parts A to C were each taken, heated to about 70°C, and mixed uniformly. Part B was gradually added to part A while stirring with a homodisper, and then part C was added at about 70°C to emulsify. The mixture was then cooled to about 40°C, and part D was added.

[0085] Formulation Example 8 Cream Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Polyglyceryl-10 Caprate 1.0 Astaxanthin 0.02 Glycerin 10.0 BG 15.0 Part B Purified water (total amount is 100) C part Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 10.0 Squalane 5.0 Diethylhexyl sebacate (Nippon Fine Chemicals) 5.0 Plandool-LG4 (Nippon Fine Chemicals) 0.3 Plandool-ISS (Nippon Fine Chemical) 0.3 D part 3-O-Ethyl ascorbic acid (Nippon Fine Chemicals) 1.0 Tranexamic acid (Nippon Fine Chemicals) 1.0 Nicotinamide 2.0 Neosolue-Aqulio (Nippon Fine Chemicals) 0.5 Neosolue-Aqua (Nippon Fine Chemical) 0.5 Tremoist-TP (Nippon Fine Chemical) 0.02 (PEG-240 / Decyltetradeceth-20 / HDI) Copolymer 2.0 Xanthan gum 0.1 Phenoxyethanol 0.2 Ethylhexylglycerin 0.2 Citric acid 0.1 Sodium citrate 0.2 -------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0086] Formulation example 9: Lotion Component Amount (wt%) -------------------------------------- Oil-in-water emulsion composition of Example 33 1.0 Neosolue-Aqulio (Nippon Fine Chemicals) 1.0 Inulin-SC (Nippon Fine Chemical) 1.0 Tremoist-TP (Nippon Fine Chemical) 0.1 Nicotinamide 5.0 Tranexamic acid (Nippon Fine Chemicals) 1.0 EDTA-2Na 0.05 Phenoxyethanol 0.4 Purified water (total amount is 100) -------------------------------------- (Preparation method) All ingredients were mixed to form a homogeneous liquid.

[0087] Formulation example 10: Lotion Component Amount (mass%) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Sucrose Laurate 1.0 PEG-40 hydrogenated castor oil 0.30 BG 3.0 Glycerin 2.0 Purified water 30.0 Part B Neosolue-DiSM (Nippon Fine Chemicals) 0.20 C part Purified water (total amount is 100) Inulin-SC (Nippon Fine Chemical) 1.0 Phenoxyethanol (appropriate amount) Tremoist-SL (Nippon Fine Chemicals) 1.0 Carboxymethyl dextran sodium 0.02 (Acrylate dimethyl taurate ammonium / vinyl pyrrolidone copolymer) 0.05 ------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0088] Formulation Example 11 Cream Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.5 Sucrose Coconut Fatty Acid 1.0 Ceramide 3 0.2 1,2-Pentanediol 5.0 Part B Phenoxyethanol 0.4 Purified water (total amount is 100) C part (C13-15) Alkanes 8.0 Vaseline 10.0 Pentaerythrityl tetraisostearate 5.0 Astaxanthin 0.01 Cetyl PG hydroxyethyl palmitamide 0.05 Dipentaerythrityl hexahydroxystearate 1.0 Cyanocobalamin 0.002 Curcumin (turmeric extract) 0.01 Hesperidin (Chinese Pepper Extract) 0.1 Cyanidin (bilberry extract) 0.01 Epigallocatechin (tea extract) 0.1 Glabridin 0.3 D part (Acryloyldimethyltaurine / Beheneth-25 methacrylate) copolymer 0.2 Crystalline cellulose 0.1 Gellan gum 0.1 Carboxyvinyl polymer 0.1 Potassium hydroxide 0.08 Phenoxyethanol 0.4 Ethylhexylglycerin 0.2 Methylparaben 0.05 Nicotinamide 5.0 Purified water 20.0 -------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0089] Formulation example 12: Moisturizing lotion Component Amount (wt%) -------------------------------------- Oil-in-water emulsion composition of Example 31 2.0 Neosolue-Aqulio (Nippon Fine Chemicals) 1.0 Glucosylceramide 0.5 Tremoist-TP (Nippon Fine Chemical) 0.1 EDTA-2Na 0.05 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) All ingredients were mixed to form a homogeneous liquid.

[0090] Formulation example 13: Serum Component Amount (wt%) ------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 1.0 Polyglyceryl-10 Palmitate 2.0 Glycerin 5.0 PPG-6-decyltetradeceth-30 0.2 PEG-30 Phytosterol 0.3 Purified water 30.0 Part B Olive oil 1.0 C part Inulin-SC (Nippon Fine Chemical) 1.0 Glycerin 10.0 Betaine 1.0 Pullulan 0.2 Ethylhexylglycerin 0.2 Polymethacryloyl lysine 0.05 Crystalline cellulose powder 0.1 Locust bean gum 0.03 Hydroxyethyl cellulose 0.05 Xanthan gum 0.05 Sodium hyaluronate 0.01 Tranexamic acid (Nippon Fine Chemicals) 2.0 Carbomer 0.06 Purified water (total amount is 100) -------------------------------------- (Preparation method) Part A was heated to about 80°C and mixed uniformly, then cooled with stirring. Part C was mixed uniformly in advance. Part B was added to Part A at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part C was added and mixed with stirring.

[0091] Formulation example 14: Serum Component Amount (mass%) ------------------------------------- Part A Glycerin 1.0 1,3-Butylene glycol 4.0 Phytocompo-SP (Nippon Fine Chemical) 5.0 Propylene glycol 3.0 Part B Diethylhexyl succinate (Nippon Fine Chemicals) 4.0 LUSPLAN PI-DA (Nippon Fine Chemical) 0.1 C part Purified water (total amount is 100) Methylparaben 0.1 Inulin-SC (Nippon Fine Chemical) 1.0 D part Carbomer (2%) neutralized with KOH 5.0 Tremoist-SL (Nippon Fine Chemicals) 2.5 Ethanol 5.0 Phenoxyethanol 0.2 Part E Oil-in-water emulsion composition of Example 29 3.0 ------------------------------------- (Preparation method) Part B, which had been uniformly dissolved at 80°C, was mixed with the uniformly dispersed Part A while stirring. Then, Part C, which had been heated to 80°C, was mixed with stirring. After cooling, Parts D and E were added while stirring.

[0092] Formulation example 15 Skin care cream Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.0 Sucrose isostearate 1.0 Purified water (total amount is 100) Part B Plandool-G (Nippon Fine Chemical) 1.0 Neosolue-Aqulio (Nippon Fine Chemicals) 1.5 Ethylhexyl palmitate (Nippon Fine Chemicals) 8.0 Diethylhexyl sebacate (Nippon Fine Chemicals) 1.0 Diisopropyl sebacate (Nippon Fine Chemicals) 1.0 Theobroma grandiflorum seed oil 1.0 Isostearate batyl 1.0 Shea butter 0.5 (Dimethicone / vinyl dimethicone) crosspolymer 0.3 (Vinyl dimethicone / lauryl dimethicone) crosspolymer 0.5 (Dimethicone / PEG-10 / 15) Crosspolymer 0.5 (PEG-15 / Lauryl Dimethicone) Crosspolymer 0.2 (Alkyl acrylate / dimethicone) copolymer 0.1 Isostearyl pivalate 0.1 Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 0.1 Stearyl alcohol 0.2 Cetanol 0.2 Sucrose coconut oil 0.1 Polyglyceryl-3 Methylglucose Distearate 0.1 Triglyceride (C10-18) 1.0 Squalane 3.0 Dimethicone 100cs 1.0 Tocopherol 0.1 Ascorbyl Tetrahexyldecanoate 1.0 Tocopheryl Ascorbyl Phosphate 1.0 Placenta extract 1.0 Oryzanol 0.3 Phytosphingosine 0.0001 Ubiquinone 0.03 Carotene 0.05 Lycopene 0.01 Astaxanthin 0.01 Lutein 0.01 Fullerene 0.001 Peanut oil 0.1 Rice bran oil 1.0 Hydrogenated castor oil 0.3 Jojoba Oil 2.0 Orange Roughy Oil 1.0 Liquid lanolin (Nippon Seika) 1.0 Lanolin (Nippon Fine Chemicals) 0.2 Polyoxyethylene Lanolin 1.0 Lanolin alcohol (Nippon Fine Chemicals) 0.3 Lanolin Alcohol Acetate 0.1 Cholesteryl acetate 0.1 Octocrylene 0.5 Sorbitan Sesquistearate 1.2 C part Tremoist-TP (Nippon Fine Chemical) 0.05 Water-soluble collagen 0.05 Hydrolyzed Collagen 0.5 Glutathione 0.3 Arbutin (Nippon Fine Chemicals) 3.0 Nicotinamide 5.0 Aurovisco CS (Oji Holding) 5.0 D part Propanediol 10.0 PPG-9 Diglyceryl 2.0 Diglycerin 1.0 Sodium pyrosulfite 0.1 Imidazolinium urea 0.1 Polyvinylpyrrolidone 0.1 Pullulan 0.1 Polyvinyl alcohol 0.1 Dehydroacetic acid 0.1 PEG-32 1.0 Polyglycerin-10 1.0 Pentetic acid 5Na 0.05 Phenoxyethanol 0.4 1,2-Pentanediol 2.0 Succinic acid 0.05 Sodium succinate (appropriate amount) Purified water (total amount is 100) -------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0093] Formulation Example 16 Gel Component Amount (wt%) ------------------------------------- Part A Hydrogenated lecithin (PC content 76-99%) 1.0 Polyglyceryl-10 Palmitate 0.4 Polyglyceryl-6 Caprylate 0.4 Polyglyceryl-10 Dioleate 0.2 β-Glycyrrhetinic acid 0.05 Phytosterols 0.05 Part B Purified water 40.0 C part (C13-15) Alkanes 3.0 Vaseline 0.5 Pentaerythrityl Tetraisostearate 2.0 Astaxanthin 0.01 Cetyl PG hydroxyethyl palmitamide 0.05 Dipentaerythrityl hexahydroxystearate 1.0 D part PPG-6-decyltetradeceth-30 0.2 PEG-30 Phytosterol 0.3 PEG-4M 0.2 Methylgluceth-10 1.0 Pyridoxine hydrochloride 0.05 Ethylhexylglycerin 0.2 Phenoxyethanol 0.4 Tranexamic acid (Nippon Fine Chemicals) 2.0 Tremoist-TP (Nippon Fine Chemical) 0.01 Hydrolyzed collagen 0.01 Purified water (total amount is 100) (PEG-240 / Decyltetradeceth-20 / HDI) Copolymer 0.05 (Acrylates / Alkyl acrylate (C10-30)) Crosspolymer 0.15 Arginine 0.25 -------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0094] Prescription Example 17 Scalp Lotion Component Amount (wt%) -------------------------------------- Oil-in-water emulsion composition of Example 20 5.0 Maltitol Liquid 0.5 PEG-60 hydrogenated castor oil 0.3 Ethanol 10.0 Tremoist-TP (Nippon Fine Chemical) 2.0 Betaine 0.2 Hydroxypropyl chitosan liquid 0.05 Carrot extract 0.1 Pyridoxine hydrochloride 0.05 Panthenol 0.1 Dipotassium glycyrrhizinate 0.1 (PEG-240 / Decyltetradeceth-20 / HDI) Copolymer 0.05 Phenoxyethanol 0.3 Purified water (total amount is 100) -------------------------------------- (Preparation method) All ingredients were mixed to form a homogeneous liquid.

[0095] Formulation example 18: Leave-in hair treatment Component Amount (wt%) ------------------------------------- Part A Polyquaternium-37 2.0 Squalane 2.0 PPG-3 Caprylyl Ether 2.0 Microcrystalline wax 0.1 Lanolin alcohol 0.2 Montan wax 0.1 Polyethylene wax 0.1 Rowlet 0.2 Ceresin 0.1 PG Dicaprylate 1.0 Almond oil 0.5 Ethylhexyl ethylhexanoate 1.0 Candelilla Wax Extract 0.1 Octyldodecyl erucate 4.5 Tocopherol acetate 0.02 Erucalactone MCT (Nippon Fine Chemicals) 2.0 Dipentaerythrityl tripolyhydroxystearate 1.5 PPG-5 Phytosteryl 0.5 Glycerin 4.0 Sorbitol 2.0 Phenoxyethanol 0.5 Part B Hydrolyzed Hyaluronic Acid 0.1 Panthenol 0.1 Hydroxypropyltrimonium Hyaluronate 0.01 Polyquaternium-11 0.2 Glycosyl trehalose 0.1 Glyceryl glucoside 0.3 Arginine 0.1 C part Purified water (total amount is 100) Hydroxypropyl starch phosphate 1.0 D part Oil-in-water emulsion composition of Example 28 10.0 -------------------------------------- (Preparation method) Part C was uniformly dispersed and heated to about 80°C. Next, part A was heated to about 80°C and dissolved. Part A was added to part C while stirring, and after uniform mixing, it was cooled to about 40°C. Next, parts B and D were added and mixed uniformly.

[0096] Formulation example 19 Leave-in scalp / hair treatment Component Amount (wt%) -------------------------------------- Part A Neosolue-Aqulio (Nippon Fine Chemicals) 1.0 Ethanol 40.0 Glycyrrhetinic acid 0.02 Erucalactone DES (Nippon Fine Chemicals) 1.5 PEG / PPG-20 / 20 Dimethicone 0.2 PEG-12 Dimethicone 0.4 Hydrogenated Retinol 0.1 Pyridoxine tris(hexyldecanoate) 0.05 Bisglyceryl ascorbate 0.3 Hexyl 3-glyceryl ascorbate 0.3 Part B Triethanolamine 0.1 Purified water (total amount is 100) (Acrylates / Alkyl acrylate (C10-30)) Crosspolymer 0.4 Carbomer 0.05 Tremoist-SL (Nippon Fine Chemicals) 1.0 (Acryloyldimethyltaurate ammonium / VP) copolymer 0.05 (Ammonium acryloyldimethyltaurate / Beheneth-25) methacrylate crosspolymer 0.1 Hydroxypropyl chitosan 0.1 Methylparaben 0.1 Phenoxyethanol 0.2 C part 3-O-Ethyl ascorbic acid (Nippon Fine Chemicals) 0.3 Nicotinamide 0.3 Pyridoxine hydrochloride 0.1 Caffeine 0.1 Glucosyl trehalose 0.1 Purified water 10.0 D part Oil-in-water emulsion composition of Example 43 20.0 -------------------------------------- (Preparation method) Part A was heated to about 50°C and dissolved. Next, part B was uniformly dispersed to form a viscous liquid. Part D was stirred at about 70°C to form a uniform liquid. Part A was added to part B while stirring, and mixed uniformly. Next, parts C and D were added, and mixed uniformly.

[0097] Prescription Example 20: Hair growth agent Component Amount (wt%) ------------------------------------- Oil-in-water emulsion composition of Example 18 1.0 Betaine 0.5 Ethanol 20.0 Menthol 0.1 Tremoist-TP (Nippon Fine Chemical) 2.0 Orange oil 0.05 Panthenyl ethyl ether 0.2 Carrot Extract 1.0 Clara Extract 2.0 Chlorella Extract 1.0 Trehalose 0.5 Nicotinamide 1.0 Piroctone Olamine 0.1 Dipotassium glycyrrhizinate 0.1 Purified water (total amount is 100) ------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homogenizer (7000 rpm). After cooling, Part C, which had been mixed in advance, was added to make a homogenous liquid.

[0098] Formulation Example 21 Leave-on hair treatment Component Amount (wt%) ---------------------------------- Part A Neosolue-Aqulio (Nippon Fine Chemicals) 2.0 Erucalactone DES (Nippon Fine Chemicals) 0.5 Cetanol 5.0 Caprylyl glucoside (50%) 1.5 Glycerin 4.0 Phenoxyethanol 0.5 Part B Ethanol 5.0 C part Polyquaternium-6 0.6 Polyquaternium-7 0.4 Polyquaternium-39 0.5 Purified water (total amount is 100) D part Oil-in-water emulsion composition of Example 43 1.0 ---------------------------------- (Preparation method) Part C was heated to about 80°C and dissolved. Next, part A was heated to about 80°C and dissolved. Part A was added to part C while stirring, and after uniform mixing, it was cooled to about 40°C. Next, parts B and D were added and mixed uniformly.

[0099] Formulation Example 22 Sunscreen cosmetics Component Amount (wt%) ----------------------------------- Part A FINEX-33W (Sakai Chemical Industry) 5.0 STR-100W (Sakai Chemical Industry) 5.0 Purified water (total amount is 100) BG 7.0 Disodium edetate 0.05 Triethanolamine 1.0 Part B Oxybenzone 3.0 Octyl paramethoxycinnamate 5.0 t-Butyl methoxybenzoylmethane 3.0 Diethylhexyl sebacate (Nippon Fine Chemicals) 8.0 Plandool-H (Nippon Fine Chemical) 2.0 Plandool-SUN (Nippon Fine Chemical) 2.0 Plandool-MAS (Nippon Fine Chemicals) 0.1 Plandool-LG1 (Nippon Fine Chemicals) 0.1 Plandool-LG2 (Nippon Fine Chemicals) 0.1 Plandool-LG3 (Nippon Fine Chemicals) 0.1 Plandool-LG4 (Nippon Fine Chemicals) 0.1 LUSPLAN PI-DA (Nippon Fine Chemical) 3.0 Cetyl ethylhexanoate 3.0 Diisopropyl sebacate (Nippon Fine Chemicals) 5.0 Dimethicone 2cs 5.0 Sucrose stearate 1.5 Polyglyceryl-10 Stearate 2.0 Stearyl alcohol 3.0 Batyl alcohol 1.0 Stearic Acid 3.0 Glyceryl Monostearate 3.0 Polyethyl acrylate 1.0 Phenoxyethanol 0.5 C part Oil-in-water emulsion composition of Example 45 1.0 ----------------------------------- (Preparation method) Part A was heated to about 80°C and thoroughly dispersed. Part B, which had been heated to about 80°C, was added thereto, and emulsified using a homogenizer. After cooling to room temperature, part C was added and stirred.

[0100] Formulation Example 23 Sunscreen cosmetics Component Amount (wt%) ----------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 2.0 Polyglyceryl-10 Caprylate 2.0 Ceramide 6 0.5 Proanthocyanidin 0.1 1,2-Pentanediol 3.0 Part B Purified water 20.0 C part 1,3-Butylene glycol 10.0 Glycerin 9.0 Phytocompo-PP (Nippon Fine Chemical) 1.0 Octocrylene 4.0 Octyl Salicylate 4.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.25 t-Butyl methoxydibenzoylmethane 1.0 Diethylhexyl sebacate (Nippon Fine Chemicals) 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 2.0 Dimethicone 1.5 Diisopropyl sebacate (Nippon Fine Chemicals) 1.0 Plandool-MAS (Nippon Fine Chemicals) 1.0 Tocopherol 0.05 D part Neosolue-AquaS (Nippon Fine Chemical) 1.0 Methylparaben (appropriate amount) Water - Amount that totals 100 Carbomer (2%) 5.0 Tremoist-SL (Nippon Fine Chemicals) 10.0 ----------------------------------- (Preparation method) Parts A and B were heated to 70°C, and part A was added to part B while stirring with a homomixer (7000 rpm), and cooled to room temperature (part E). Parts C and D were heated to about 70°C and dissolved. Part C was added to part E at room temperature while stirring with a homomixer (7000 rpm) to emulsify, and part D was further added and mixed with stirring.

[0101] Formulation Example 24 Sunscreen cosmetics Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 2.0 Polyglyceryl-10 Oleate 1.0 DPG 2.0 BG 5.0 Part B Purified water (total amount is 100) C part Diisopropyl sebacate (Nippon Fine Chemicals) 2.0 Oxybenzone 3.0 Octyl paramethoxycinnamate 5.0 t-Butyl methoxybenzoylmethane 3.0 Ethylhexyl palmitate 5.0 Carbomer (2% aqueous solution) 10.0 D part Purified water 5.0 Sodium hydroxide 0.1 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to 50°C, and part A was added to part B while stirring with a homomixer (4500 rpm), and cooled to room temperature (part E). Part C was added to part E, and emulsified at room temperature with a homomixer (4500 rpm), and part D was added and mixed with stirring.

[0102] Formulation Example 25 Sunscreen cosmetics Component Amount (wt%) -------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 0.5 Polyglyceryl-10 Dicaprylate 2.0 1,2-Hexanediol 2.0 PG 3.0 Glycerin 0.5 Part B Purified water (total amount is 100) C part Diisopropyl sebacate (Nippon Fine Chemicals) 1.0 Oxybenzone 3.0 Octyl paramethoxycinnamate 5.0 t-Butyl methoxybenzoylmethane 3.0 Ethylhexyl palmitate (Nippon Fine Chemicals) 5.0 FINEX-33W (Sakai Chemical Industry) 5.0 STR-100W (Sakai Chemical Industry) 5.0 (Acrylates / Alkyl acrylate (C10-30)) Crosspolymer (2% aqueous solution) 10.0 D part Purified water 5.0 Sodium hydroxide 0.1 Phenoxyethanol 0.4 -------------------------------------- (Preparation method) Parts A and B were heated to 50°C, and part A was added to part B while stirring with a homomixer (4500 rpm), and cooled to room temperature (part E). Part C was added to part E, and emulsified at room temperature with a homomixer (4500 rpm), and part D was added and mixed with stirring.

[0103] Formulation Example 26 Liquid Foundation Component Amount (wt%) --------------------------------- Part A PrimeLipid-PI (Nippon Fine Chemical) 1.0 Octyltriazone 1.5 Ethylhexyl methoxycinnamate 1.0 Quaternium-18 Hectorite 0.5 Part B Cyclomethicone 25.0 Polyether modified silicone mixture 5.0 (BY22-008M manufactured by Toray Dow Corning Silicone Co., Ltd.) Polyglyceryl-2 Isostearate 1.0 Titanium oxide-iron oxide mixture 12.5 Mica 6.0 C part Glycerin 5.0 Neosolue-AquaS (Nippon Fine Chemical) 0.4 Methylparaben 0.2 Tranexamic acid (Nippon Fine Chemicals) 2.0 Purified water (total amount is 100) D part Oil-in-water emulsion composition of Example 28 5.0 --------------------------------- (Preparation method) Part A was heated to about 80°C and thoroughly dispersed. Part B heated to about 80°C was added thereto, and then part C heated to about 80°C was added thereto, and emulsified using a homogenizer. After cooling to room temperature, part D was added and stirred.

[0104] Formulation Example 27 Foundation Component Amount (wt%) ------------------------------------ Part A Isododecane 10.0 Caprylic / capric triglyceride (Nippon Fine Chemicals) 4.0 Ethylhexyl methoxycinnamate 3.0 Plandool-SUN (Nippon Fine Chemical) 1.0 Plandool-LG2 (Nippon Fine Chemicals) 1.0 Plandool-LG4 (Nippon Fine Chemicals) 1.0 Vaseline 1.0 Isotridecyl isononanoate 2.0 Ascorbyl Tetrahexyldecanoate 0.1 Dextrin palmitate 0.3 Sorbitan isostearate 1.5 Tribehenin 0.5 (Butyl acrylate / glycol dimethacrylate) crosspolymer, silica, (Methyl methacrylate / glycol dimethacrylate) crosspolymer mixture 2.0 Boron nitride 1.0 Polysorbate 20 2.0 PEG-60 hydrogenated castor oil 1.0 Disteardimonium hectorite (20%) 2.5 Polypropylsilsesquioxane, Cyclopentasiloxane mixture 1.0 Mica 15.0 Talc 4.0 Zinc oxide 5.0 Titanium dioxide 10.0 Iron oxide 1.5 Part B Water - Amount that totals 100 DPG 4.0 Maltitol (75% liquid) 1.0 Neosolue-AquaS (Nippon Fine Chemical) 0.4 Sodium chloride 1.0 BG 1.0 Tremoist-SL (Nippon Fine Chemicals) 1.0 Ethanol 0.5 Phenoxyethanol 0.3 C part Oil-in-water emulsion composition of Example 27 4.0 ------------------------------------ (Preparation method) Part A was heated to about 70°C and thoroughly stirred to disperse uniformly. Part B was heated to about 70°C and uniformly dissolved. Part B was added to Part A while stirring to emulsify. After cooling, Part C was added and stirred.

[0105] Prescription Example 28 Cream Component Amount (mass%) ------------------------------------- Part A Phytocompo-SP (Nippon Fine Chemical) 5.0 Glycerin 10.0 BG 1.0 Pentylene glycol 2.0 Part B Squalane 7.0 Plandool-MAS (Nippon Fine Chemicals) 5.0 Behenyl Alcohol 3.0 Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 2.0 Cetearyl Alcohol 1.5 Cetyl palmitate 1.5 Dimethicone (10cs) 0.5 Stearic acid 1.0 Tocopherol 0.1 C part Purified water (total amount is 100) Inulin-SC (Nippon Fine Chemical) 1.0 Xanthan gum (2% aqueous solution) 3.0 Phenoxyethanol 0.5 D part Carbomer (2%) neutralized with KOH 7.0 Part E Oil-in-water emulsion composition of Example 22 10.0 ------------------------------------- (Preparation method) Part A was heated to 70°C and uniformly dispersed, and then part B was mixed with part A, which was uniformly dissolved at 70°C, while stirring. Then, part C, which was heated to 70°C, was mixed with part D. After cooling, parts D and E were added with stirring.

[0106] Prescription Example 29 Cream Component Amount (mass%) ------------------------------------- Part A Hydrogenated lecithin (PC content 50-75%) 1.5 Polyglyceryl-10 Oleate 1.5 Ceramide 6 0.5 Proanthocyanidin 0.1 BG 10.0 Part B Purified water (total amount is 100) C part Squalane 7.0 Plandool-MAS (Nippon Fine Chemicals) 1.0 Behenyl Alcohol 1.0 Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 1.0 Cetearyl alcohol 0.5 Cetyl palmitate 1.0 Dimethicone (10cs) 0.5 Stearic acid 0.1 Tocopherol 0.1 Carbomer (2% aqueous solution) 7.0 D part Purified water 20.0 Potassium hydroxide 0.1 ------------------------------------- (Preparation method) Part A and Part B were heated to 70°C, and Part A was added to Part B while stirring with a homomixer (2000 rpm), and cooled to room temperature (Part E). Part C was mixed uniformly in advance. Part C was added to Part E at room temperature while stirring with a homomixer (4000 rpm) to emulsify, and then Part D was added and mixed with stirring.

[0107] In the above formulation, details of the ingredients listed by product name are as follows: Plandool-H: Dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl) Plandool-G: Dimer dilinoleyl bis(behenyl / isostearyl / phytosteryl) dimer dilinoleate Plandool-ISS: Phytosteryl isostearate Plandool-SUN: Sunflower seed oil fatty acid phytosteryl Plandool-MAS: Phytosteryl macadamiate 〇Plandool-LG1: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) Plandool-LG2: Di(phytosteryl / octyldodecyl) lauroyl glutamate 〇Plandool-LG3: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) 〇Plandool-LG4: Lauroyl glutamate di(phytosteryl / octyldodecyl / behenyl) LUSPLAN PI-DA: Dimer dilinoleate di(isostearyl / phytosteryl) LUSPLAN SR-DM4: Dimer dilinoleyl dimer dilinoleate, tri(caprylic / capric acid)glyceryl Neosolue-Aqulio: bisethoxydiglycol cyclohexanedicarboxylate Neosolue-Aqua: Polyglyceryl-10 (eicosane diacid / tetradecanedioic acid), glycerin Neosolue-AquaS: Polyglyceryl-10 (eicosane diacid / tetradecanedioic acid), glycerin Neosolue-DiSM: Diisostearyl malate Phytocompo-PP: Hydrogenated lecithin, phytosterol Phytocompo-SP: Hydrogenated lecithin, phytosterol, BG, glycerin PrimeLipid-PI: Hydrogenated lecithin, phytosterol, lecithin, tocopherol Tremoist-TP: Tremella fuciformis polysaccharide Tremoist-SL: Tremella fuciformis polysaccharide aqueous solution (1%) 〇Inulin-SC: Inulin Erucalactone DES: γ-docosalactone, diethyl sebacate Erucalactone MCT: γ-docosalactone, tri(caprylic acid / capric acid)glyceryl STR-100W: Titanium oxide, hydrated silica FINEX-33W: Zinc oxide, hydrated silica

Claims

1. An emulsifier composition for an oil-in-water emulsion composition, comprising the following components (A) and (B), a mass ratio of components (A1) to (A2) is 95:5 to 15:85, and component (A) is dispersed in water. (A) A lipid composition comprising the following components (A1) and (A2): (A1) One or more selected from the group consisting of mono- or diesters of fatty acids having 8 to 22 carbon atoms and polyglycerols having a polymerization degree of 6 to 22, and monoesters of fatty acids having 8 to 22 carbon atoms and sucrose. (A2) Phospholipid (B) Water

2. 2. The emulsifier composition according to claim 1, wherein the component (A2) is hydrogenated lecithin.

3. The emulsifier composition according to claim 2, characterized in that component (A) further contains, as component (A3), one or more selected from ceramides, sterols, carotenoids, tocopherols, lipoic acid and coenzyme Q10, and the content of component (A3) in component (A) is 36 mass% or less.

4. 4. An oil-in-water emulsion composition produced by stirring and mixing the emulsifier composition according to claim 1 with an oily component.

5. 5. The oil-in-water emulsion composition according to claim 4, which is used in a cosmetic or external skin preparation.

6. A method for producing an oil-in-water emulsion composition, comprising stirring and mixing the emulsifier composition according to any one of claims 1 to 3 with an oily component.

7. The method for producing an oil-in-water emulsion composition according to claim 6, wherein the stirring and mixing is carried out without heating.

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