Topical preparation for skin

Abstract

To provide a topical preparation for skin that exhibits moisture retention and allows reduction of stickiness.SOLUTION: A topical preparation for skin comprises (A) an aloe extract and (B) a polysaccharide, where the polysaccharide (B) includes a structural unit represented by a specific formula.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present disclosure relates to, for example, topical preparations for skin. [Background technology]

[0002] The moisturizing effect for maintaining fresh skin is one of the important effects of topical skin preparations. Conventionally, methods for imparting a moisturizing effect have been used, for example, to inhibit evaporation of water from the skin by binding water with a hydrophilic hygroscopic substance called NMF (natural moisturizing factor), or to prevent water loss by encapsulating water in NMF (for example, Patent Document 1). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Japanese Patent Application Laid-Open No. 2002-179522 Summary of the Invention [Problem to be solved by the invention]

[0004] However, the technology described in Patent Document 1 leaves room for improvement in terms of excellent moisturizing properties and suppression of sticky feeling. Therefore, the problem to be solved by the present disclosure is to provide a new topical preparation for skin and the like that is excellent in moisturizing properties and can suppress sticky feeling. [Means for solving the problem]

[0005] The present inventors conducted extensive research to solve the problems of conventional topical skin preparations, such as the lack of moisturizing effect, and discovered that the use of aloe extract in combination with specific polysaccharides allows the preparation to contain free water, i.e., water molecules not bound by hydrogen bonds. This free water is released from the cosmetic preparation upon application and directly delivers moisture to the skin. Furthermore, the water-retaining structure of aloe, acetylated mannan, forms an excellent moisture film that covers the skin, resulting in a topical skin preparation with superior moisturizing properties compared to conventional preparations, leading to the completion of the present invention.

[0006] (1) According to one embodiment of the present disclosure, there is provided a topical skin preparation comprising (A) an aloe extract and (B) a polysaccharide, wherein the polysaccharide (B) comprises a structural unit represented by the following formula (1): [ka] This form of external preparation for skin has excellent moisturizing properties and can suppress sticky feeling.

[0007] (2) In the topical skin preparation described in (1) above, the content of the aloe extract (A) may be 0.10% by mass or more and 10.0% by mass or less, and the content of the polysaccharide (B) may be 0.01% by mass or more and 1% by mass or less, based on the total amount of the topical skin preparation. This form of topical skin preparation is superior in terms of moisturizing properties and stickiness.

[0008] (3) In the topical skin preparation according to (1) or (2), the weight average molecular weight of the polysaccharide (B) is 10 6 The external preparation for skin in this form has even better moisturizing properties.

[0009] The present disclosure can be realized in various forms, for example, as a method for producing an external preparation for skin, or the like. [Brief explanation of the drawings]

[0010] [Figure 1] FIG. 2 is an explanatory diagram showing the intrinsic viscosity of a test sample (B-1X X lot). [Figure 2] FIG. 1 is an explanatory diagram showing a calibration curve obtained from the intrinsic viscosity of pullulan. DETAILED DESCRIPTION OF THE INVENTION

[0011] The topical skin preparation of the present disclosure comprises (A) an aloe extract and (B) a polysaccharide, and the polysaccharide (B) comprises a structural unit represented by the following formula (1): [ka]

[0012] In the following description, for convenience, the aloe extract (A) will also be referred to as "component A," and the polysaccharide containing the structural unit represented by the above formula (1) will also be referred to as "component B."

[0013] The aloe extract (A), component A, is obtained by extracting the leaves, flowers, seeds, or roots, preferably the leaves, of Aloe vera (Aloe barbadensis Mill.), Cape aloe (Aloe ferox Mill., Aloe africana Mill., Aloe spicata Baker), or Aloe arborescens Mill., which belong to the genus Aloe, using a solvent. The leaves, flowers, seeds, or roots are preferably cut or crushed as appropriate before use. In the present disclosure, the term "aloe extract" encompasses not only aloe extracts obtained by extraction with water and / or organic solvents, but also squeezed aloe juice. As the aloe extract in the present disclosure, it is preferable to use squeezed aloe juice. In the present disclosure, the term "aloe juice" encompasses aloe juice that has been further processed by extraction, purification, or the like. Component A is not particularly limited, but from the viewpoint of water storage, it is preferable to use a product obtained by removing aloin and other substances from the sap of the leaves of Aloe vera (L.) Burm.f. (Aloe barbadensis Mill.) (Liliaceae), drying the resulting powder, dissolving it in water, adding 1,3-butylene glycol, and filtering as necessary. A preferred example of a commercially available product of component A is Biocelact (registered trademark) Aloe Vera B (manufactured by Ichimaru Pharcos Co., Ltd.). Aloe vera is a plant that can survive under high-temperature, dry conditions, and has excellent water-storing cells, providing excellent protection against desiccation.

[0014] The polysaccharide (B) containing the structural unit represented by the formula (1) as component B is not particularly limited, but examples thereof include Alcaligenes-produced polysaccharides, which are polysaccharides produced by microorganisms. More specifically, examples thereof include products of Alcaligenes latus B-16 strain bacteria (FERM BP-2015). Commercially available products of component B include Alcasealan (registered trademark) (manufactured by Hakuto Co., Ltd.) (INCI name: Alcaligenes Polysacchaides, display name: Alcaligenes-produced polysaccharides).

[0015] In general, the main chain of a polysaccharide is composed of neutral or acidic sugars, and the main chain does not contain OH groups. - , COOH - Since it is a sugar having a group, it forms hydrogen bonds between its own chains or via salt or water molecules, making it easier to form a crystalline structure. In contrast, Component B of the present disclosure contains deoxysugars with hydrophobic groups in their side chains, allowing the main chains to spread apart. As a result, a large network structure can be formed, and this large network can hold free water. Furthermore, the multiple types of polysaccharides contained in Component A of the present disclosure can densify the network structure. As a result, Component A can store water and Component B can release water, thereby providing moisture to the skin and effectively suppressing water evaporation through the moisture film, resulting in excellent moisturizing properties. In addition, the moisture film formed by Component A can give the skin a film-like feel. Furthermore, Component B, a hydrophilic polymer with a large molecular weight, forms a large network structure, and by entangling Component A, a water-storing component, it is possible to maintain a good balance between free water and stored water. From the perspective of forming a larger network structure, the average molecular weight of Component B is 10 6 It is preferable that the average molecular weight of component B is 10 or more. 6 The above can improve entanglement with component A. In the present disclosure, the "average molecular weight of component B" means the molecular weight based on pullulan as a standard substance with a known molecular weight, and more specifically, means the molecular weight calculated by the method shown in the examples described later.

[0016] The content of component A is preferably 0.10% by mass or more and 10.0% by mass or less, and more preferably 1.00% by mass or more and 5.0% by mass or less, based on the total amount of the topical skin preparation. Furthermore, the content of component A is preferably 0.0005% by mass or more and 0.05% by mass or less, and more preferably 0.005% by mass or more and 0.025% by mass or less, based on the total amount of the topical skin preparation, in terms of solid content excluding water. By having the content of component A be 0.10% by mass or more based on the total amount of the topical skin preparation, the moisturizing effect can be further enhanced. Similarly, by having the content of component A be 0.0005% by mass or more based on the total amount of the topical skin preparation, in terms of solid content excluding water, the moisturizing effect can be further enhanced. Furthermore, by having the content of component A be 10.0% by mass or less based on the total amount of the topical skin preparation, the sticky feeling can be effectively suppressed. Similarly, by ensuring that the content of Component A is 0.05 mass % or less, calculated as solid content excluding water, based on the total amount of the topical preparation for skin, sticky feeling can be effectively suppressed.

[0017] The content of Component B is preferably 0.01% by mass or more and 1% by mass or less, and more preferably 0.05% by mass or more and 0.5% by mass or less, based on the total amount of the topical skin preparation. By having the content of Component B be 0.01% by mass or more based on the total amount of the topical skin preparation, the moisturizing effect can be further enhanced and the sticky feeling caused by the dominant feel of Component A can be suppressed. Furthermore, by having the content of Component B be 1% by mass or less based on the total amount of the topical skin preparation, an excessive increase in the product viscosity can be suppressed, thereby improving handleability.

[0018] Therefore, from the viewpoints of moisturizing properties and stickiness, the topical skin preparation of the present disclosure preferably contains 0.10% to 10.0% by mass of component A and 0.01% to 1% by mass of component B, relative to the total amount of the topical skin preparation, and more preferably contains 1.00% to 5.0% by mass and 0.05% to 0.5% by mass of component B. Furthermore, from the viewpoints of moisturizing properties and stickiness, the content ratio of component A to component B in the topical skin preparation (component A / component B) is preferably 0.1 to 500, more preferably 1 to 200, and even more preferably 10 to 100.

[0019] The topical skin preparation of the present disclosure contains free water, thereby improving moisturizing properties compared to conventional topical skin preparations. Conventional topical skin preparations contain many ionic components and polar organic substances, and water molecules are bound to these components by hydrogen bonds. Therefore, conventional topical skin preparations provide insufficient moisture to the skin. This is particularly evident in creams containing a low proportion of water. The present inventors have discovered that by incorporating component A and component B into a topical skin preparation, even a cream or other formulation can contain free water and provide sufficient skin moisture. Specifically, they have found that a larger molecular weight of the hydrophilic polymer is advantageous for constructing a large hydrophilic polymer network, and that blending multiple hydrophilic polymers with different molecular weights to create a denser hydrophilic polymer network results in a denser network and improved moisturizing properties.

[0020] The topical skin preparation of the present disclosure encompasses various formulations and forms depending on its intended use, and may optionally contain ingredients such as UV protection agents, whitening agents, skin (cell) activators, astringents, anti-inflammatory (anti-inflammatory) agents, antioxidants, moisturizers, fragrances, organic solvents, oils, pigments, surfactants, thickeners, and dyes, which are incorporated into pharmaceuticals, quasi-drugs, and cosmetics. Purified water, antibacterial agents, transdermal absorption enhancers, cooling agents, preservatives, chelating agents, anti-fading agents, buffers, and powders may also be optionally added. The present disclosure does not restrict the incorporation of these various additives into the topical skin preparation of the present disclosure, provided that the intended effect is not impaired.

[0021] Examples of ultraviolet inhibitors include, but are not limited to, organic compound-based ultraviolet absorbers and inorganic compound-based ultraviolet scattering agents. Examples of ultraviolet absorbers include, but are not limited to, para-aminobenzoic acid-based ultraviolet absorbers, cinnamic acid-based ultraviolet absorbers, salicylic acid-based ultraviolet absorbers, and benzophenone-based ultraviolet absorbers. Examples of para-aminobenzoic acid-based ultraviolet absorbers include, but are not limited to, para-aminobenzoic acid, glyceryl para-aminobenzoate, ethyl dihydropropyl para-aminobenzoate, amyl para-dimethyl para-aminobenzoate, octyl para-methyl para-aminobenzoate, ethyl para-aminobenzoate, and isobutyl para-aminobenzoate. Examples of cinnamic acid-based ultraviolet absorbers include, but are not limited to, isopropyl para-methoxycinnamate, diisopropyl cinnamate, octyl methoxycinnamate, and glyceryl di-para-methoxycinnamate mono-2-ethylhexanoate. Examples of salicylic acid-based ultraviolet absorbers include, but are not limited to, homomethyl salicylate, octyl salicylate, phenyl salicylate, triethanolamine salicylate, amyl salicylate, benzyl salicylate, p-tert-butylphenyl salicylate, ethylene glycol salicylate, salicylic acid, etc. Examples of benzophenone-based ultraviolet absorbers include, but are not limited to, dihydroxybenzophenone, tetrahydroxybenzophenone, oxybenzone, oxybenzone sulfonic acid, sodium hydroxymethoxybenzophenone sulfonate, dihydroxydimethoxybenzophenone, 2-hydroxychlorobenzophenone, dioxybenzone, sodium dihydroxydimethoxybenzophenone disulfonate, 2-hydroxy-4-methoxy-4'-methylbenzophenone, octabenzone, etc. Other ultraviolet absorbers are not particularly limited, but examples thereof include urocanic acid, ethyl urocanate, 4-tert-4'-methoxydibenzoylmethane, 2-(2'-hydroxy-5'-methylphenyl)benzotriazole, anthranilic acid, etc. The content of the ultraviolet absorber may be set depending on the type of ultraviolet absorber, and may be, for example, 0.1% by mass or more and 10% by mass or less based on the total amount of the topical skin preparation.

[0022] The inorganic compound used as the UV scattering agent is not particularly limited, but examples thereof include titanium oxide, zinc oxide, cerium oxide, zirconium oxide, iron oxide, etc. The content of the UV scattering agent may be set depending on the type of UV scattering agent, and may be, for example, 1% by mass or more and 30% by mass or less relative to the total amount of the topical skin preparation.

[0023] The whitening agent is not particularly limited, but examples thereof include tyrosinase inhibitors, endothelin antagonists, α-MSH inhibitors, glabridin, glabrene, liquiritin, isoliquiritin, ellagic acid and its derivatives and salts thereof, kojic acid and its derivatives and salts thereof, hydroquinone such as arbutin and its derivatives and salts thereof, ascorbic acid, sodium ascorbate, ascorbyl stearate, ascorbyl palmitate, ascorbyl dipalmitate, magnesium ascorbyl phosphate and other vitamin C derivatives and salts thereof, resorcinol and its derivatives and salts thereof, neoagarobiose, agarose oligosaccharide, asparagus extract, Althea extract, Ibukitoranoi extract, Inchinko extract, E Examples of such extracts include pea extract, pearl berry extract, Scutellaria root extract, Ononis extract, seaweed extract, fire thorn extract, licorice extract, bramble extract, Sophora root extract, brown sugar extract, cinnamon root extract, Gokahi extract, wheat germ extract, Chinese rhizome extract, hawthorn extract, sunflower extract, peony extract, white lily extract, sappanwood extract, mulberry extract, soybean extract, placenta extract, elm extract, tea extract, angelica extract, molasses extract, multiflora rose extract, white birch extract, grape seed extract, beech extract, flordemanita extract, hop extract, squid extract, mocca extract, saxifrage extract, coix seed extract, and monk fruit extract, and one or more of these may be appropriately selected and blended. The content of the whitening agent component may be set depending on the type of whitening agent component, and may be, for example, 0.01% by mass or more and 10% by mass or less of the active ingredient relative to the total amount of the topical skin preparation.

[0024] Examples of skin (cell) activator components include, but are not limited to, deoxyribonucleic acid and its salts, adenylic acid derivatives such as adenosine triphosphate and adenosine monophosphate and their salts, ribonucleic acid and its salts, nucleic acid-related substances such as cyclic AMP, cyclic GMP, flavin adenine nucleotide, guanine, adenine, cytosine, thymine, xanthine and their derivatives such as caffeine and theophylline, and their salts; baby calf blood extract, deproteinized serum extract, spleen extract, chicken egg components, cockscomb extract, shell extract, shellfish meat extract, royal jelly, silk protein and its degradation products or derivatives thereof, hemoglobin or its degradation products, lactoferrin or its degradation products, molluscan products such as squid ink; fish meat extract; extracts derived from animals such as mammals, birds, shellfish, insects, fish, mollusks, and crustaceans; and extracts derived from microorganisms selected from fermentation metabolites such as yeast extract, lactic acid bacteria extract, and bifidobacterium extract.Furthermore, vitamin A such as retinol and its derivatives (retinol palmitate, retinol acetate, etc.), retinal and its derivatives, dehydroretinal, carotene and other carotenoids, thiamines (thiamine hydrochloride, thiamine sulfate), riboflavins (riboflavin, riboflavin acetate, etc.), pyridoxines (pyridoxine hydrochloride, pyridoxine dioctanoate, etc.), flavin adenine nucleotide, cyanocobalamin, folic acids, nicotinic acids (nicotinamide, benzyl nicotinate, etc.), choline and other vitamin B, ascorbic acid and its derivatives of the vitamin C group, ergocalciferol (vitamin D2), cholecalciferol (vitamin D3), and dihydrotachysterol of the vitamin D group, tocopherol and its derivatives and ubiquinones of the vitamin E group, and phytonadione (vitamin K1), menaquinone (vitamin K2), and menadione ( Vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, gamma-oryzanol, orotic acid, vitamin P (rutin, eriocitrin, hesperidin), vitamin U, etc.; plant-derived extracts such as apricot extract, ginkgo extract, ginseng extract, barley extract, orange extract, cucumber extract, kiwi extract, shiitake mushroom extract, horsetail extract, Swertia japonica extract, Chinese cabbage extract, chili pepper extract, garlic extract, carrot extract, Poria cocos extract, peach extract, lettuce extract, lemon extract, Ganoderma lucidum extract, rosemary extract, hinokitiol, and cepharanthine; alpha- and gamma-linolenic acid, eicosapentaenoic acid and their derivatives; estradiol and its derivatives and their salts; and organic acids such as glycolic acid, succinic acid, lactic acid, and salicylic acid and their derivatives and their salts. One or more of these skin activators may be appropriately selected and blended in. The content may be set depending on the type of skin activator component, and may be, for example, 0.1% by mass or more and 20% by mass or less of the active ingredient relative to the total amount of the topical skin preparation.

[0025] The astringent is not particularly limited, but examples thereof include zinc sulfophenolate, sodium sulfophenolate, various plant extracts, etc. The plant in the plant extract is not particularly limited, but examples thereof include arnica, hawthorn, cinchona, salvia, linden tree, ginseng, juniper, rosemary, St. John's wort, ginkgo, melissa, ononis, horse chestnut, Swertia japonica, garlic, chamomile, thyme, mint, nettle, chili pepper, ginger, hops, horse chestnut, lavender, carrot, mustard, cassia, pine, cnidium, elderberry, Japanese parsley, jasmine, peony, Japanese bayberry, Houttuynia cordata, and water hyacinth. Examples of astringents include radish, Japanese laurel, calendula, lily of the valley, gentian, grape, littoral, bitter orange, yuzu, calamus, summer mandarin, witch hazel, merry lotus, fennel, Japanese pepper, peony, eucalyptus, mugwort, emmeisou, rice, sophora flavescens, ginger, clove, walnut leaf, Scutellaria root, sage, hops, rosemary, Polygonum multiflorum, Coptis chinensis, Phellodendron bark, Chinese yew, dried orange peel, Chinese daisy, propolis, taxus, tannin, birch tar, royal jelly, and yeast extract. One or more of these astringents may be appropriately selected and blended. The content may be set depending on the type of astringent component, but is preferably 0.01% to 3% by weight of the total amount of the topical skin preparation.

[0026] The anti-inflammatory agent is not particularly limited, but examples thereof include zinc oxide, sulfur and its derivatives, glycyrrhizinic acid, dipotassium glycyrrhizinate, monoammonium glycyrrhizinate, and other glycyrrhizinic acid and its derivatives and salts thereof, β-glycyrrhetinic acid, stearyl glycyrrhetinate, disodium 3-succinyloxyglycyrrhetinate, and other glycyrrhetinic acid and its derivatives and salts thereof, tranexamic acid, chondroitin sulfate, mefenamic acid, phenylbutazone, indomethacin, ibuprofen, ketoprofen, allantoin, guaiazulene and its derivatives and salts thereof, various extracts of microorganisms, animals, and plants, etc. One or more of these anti-inflammatory agents may be appropriately selected and blended.

[0027] The antioxidant is not particularly limited, but examples thereof include vitamin A such as retinol, dehydroretinol, retinol acetate, retinol palmitate, retinal, retinoic acid, vitamin A oil, and derivatives thereof and salts thereof; carotenoids such as α-carotene, β-carotene, γ-carotene, cryptoxanthin, astaxanthin, fucoxanthin, and derivatives thereof; vitamin B such as pyridoxine, pyridoxal, pyridoxal-5-phosphate, pyridoxamine, and derivatives thereof and salts thereof; ascorbic acid; sodium ascorbate; Vitamin C derivatives and their salts, such as ascorbyl stearate, ascorbyl palmitate, ascorbyl dipalmitate, and magnesium ascorbyl phosphate; vitamin D derivatives and their salts, such as ergocalciferol, cholecalciferol, and 1,2,5-dihydroxycholecalciferol; α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopheryl acetate, nicotinic acid, Vitamin E derivatives and salts thereof, such as tocopherol titanate, Trolox and its derivatives and salts thereof, dihydroxytoluene, butylhydroxytoluene, butylhydroxyanisole, dibutylhydroxytoluene, α-lipoic acid, dehydrolipoic acid, glutathione and its derivatives and salts thereof, uric acid, erythorbic acid, erythorbic acid salts, such as sodium erythorbate, gallic acid, propyl gallate and other gallic acid derivatives and salts thereof, rutin, α-glycosyl-rutin and other rutin derivatives and salts thereof, carnosine and its derivatives, Salts thereof, homocarnosine and its derivatives and salts thereof, anserine and its derivatives and salts thereof, carcinine and its derivatives and salts thereof, flavanones, flavones, anthocyanins, anthocyanidins, flavonols, quercetin, quercitrin, myricetin, fisetin, hamamelitannin, catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate, flavonoids such as epigallocatechin gallate, tannic acid, caffeic acid, ferulic acid, protocatechuic acid, chalcone, oryzanol, carnosol, sesamol,Examples of antioxidants include sesamin, sesamolin, zingerone, curcumin, tetrahydrocurcumin, clovamide, deoxyclovamide, shogaol, capsaicin, vanillylamide, ellagic acid, bromophenol, flavoglacin, melanoidin, riboflavin, riboflavin butyrate, flavin mononucleotide, flavin adenine nucleotide, ubiquinone, ubiquinol, mannitol, bilirubin, cholesterol, ebselen, selenomethionine, ceruloplasmin, transferrin, lactoferrin, albumin, superoxide dismutase, catalase, glutathione peroxidase, metallothionein, O-phosphono-pyridoxylidenerhodamine, etc. One or more of these antioxidants may be appropriately selected and blended. The content of the antioxidant (antioxidant component) may be set depending on the type of antioxidant, and may be, for example, 0.1% by mass or more and 10% by mass or less relative to the total amount of the topical skin preparation.

[0028] The moisturizing agent is not particularly limited, but examples thereof include polyhydric alcohols such as glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, polyethylene glycol, and sorbitol; main components of NMF (natural moisturizing factor) such as pyrrolidone carboxylate and lactate; hyaluronate; and various plant extracts. One or more of these moisturizing agents may be appropriately selected and blended. The content of the moisturizing agent may be determined depending on the type of moisturizing agent, and may be, for example, 0.1% by mass or more to 20% by mass or less of the total amount of the topical skin preparation as an active ingredient.

[0029] The fragrance is not particularly limited, and examples thereof include natural fragrances and synthetic fragrances. Examples of natural fragrances include, but are not particularly limited to, plant-based fragrances such as rose oil, jasmine oil, neroli oil, lavender oil, tuberose oil, ylang-ylang oil, clary sage oil, clove oil, peppermint oil, geranium oil, patchouli oil, sandalwood oil, cinnamon oil, coriander oil, nutmeg oil, pine oil, vanilla oil, Peru balsam oil, banana oil, apple oil, fennel oil, tonka bean oil, pepper oil, lemon oil, orange oil, bergamot oil, opoponax oil, vetiver oil, orris oil, oakmoss oil, anise oil, and bois de rose oil, and animal-based fragrances such as musk oil, civet oil, castoreum oil, and ambergris oil.

[0030] The synthetic fragrance is not particularly limited, but examples thereof include hydrocarbons such as limonene and β-caryophylline, alcohols such as cis-3-hexenol, linalool, farnesol, β-phenylethyl alcohol, geraniol, citronellol, terpineol, menthol, santalol, bacdanol, and brahmanol, aldehydes such as lilanol, lilial, 2,6-nonadienal, citral, and α-hexylcinnamic aldehyde, β-ionone, l-carvone, cyclopentadecanone, damascone, methyl ionone, iron, and isoe super. Examples of suitable fragrances include ketones such as acetyl cedrene and muscone, esters such as benzyl acetate, methyl dihydrojasmonate, methyl jasmonate, linalyl acetate and benzyl benzoate, lactones such as γ-undecalactone, jasmine lactone, cyclopentadecanolide and ethylene brassylate, oxides such as galacsolid, ambroxan and rose oxide, phenols such as eugenol, nitrogen-containing compounds such as indole, acetals such as phenylacetaldehyde dimethyl acetal, and Schiff bases such as aurantiol. Fragrances are generally not used alone, but are often used as blended fragrances in which multiple types are combined depending on the purpose. These fragrances may be dissolved or dispersed in an organic solvent or oil and then incorporated into topical skin preparations.

[0031] The organic solvent is not particularly limited, but examples thereof include ethanol, acetone, ethyl acetate, butyl acetate, 1,3-butylene glycol, ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, glycerin, butanol, and propanol, and one or more of these may be used.

[0032] The oil agent is not particularly limited, and any of natural oils, synthetic oils, or solid, semi-solid, liquid, or other oils can be used regardless of their raw material or form. For example, any of hydrocarbons, waxes, fatty acids, higher alcohols, ester oils, silicone oils, fluorine-based oils, etc. can be used. Specific examples include hydrocarbons such as squalane, squalene, ceresin, paraffin, paraffin wax, liquid paraffin, pristane, polyisobutylene, microcrystalline wax, and petrolatum; waxes such as jojoba oil, beeswax, carnauba wax, candelilla wax, and spermaceti; animal oils such as beef tallow, beef leg fat, beef bone fat, hardened beef tallow, hardened oil, turtle oil, lard, horse fat, mink oil, liver oil, and egg yolk oil; lanolin, liquid lanolin, reduced lanolin, lanolin alcohol, and hard lanolin. Lanolin derivatives such as lanolin acetate, lanolin fatty acid isopropyl, POE lanolin alcohol ether, POE lanolin alcohol acetate, lanolin fatty acid polyethylene glycol, and POE hydrogenated lanolin alcohol ether; and fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid, oleic acid, arachidonic acid, docosahexaenoic acid (DHA), isostearic acid, and 12-hydroxystearic acid.Also, higher alcohols such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, behenyl alcohol, hexadecyl alcohol, oleyl alcohol, isostearyl alcohol, hexyldodecanol, octyldodecanol, cetostearyl alcohol, 2-decyltetradecynol, cholesterol, phytosterol, sitosterol, lanosterol, POE cholesterol ether, and monostearyl glycerin ether (batyl alcohol); diisobutyl adipate, 2-hexyldecyl adipate, di-2-heptylundecyl adipate, N-alkyl glycol monoisostearate, isocetyl isostearate, trimethylolpropane triisostearate, ethylene glycol di-2-ethylhexanoate, cetyl 2-ethylhexanoate, trimethylolpropane tri-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, cetyl octanoate, octanoic acid, octyl hydroxybenzoate ... Childodecyl Gum Esters, Oleyl Oleate, Octyldodecyl Oleate, Decyl Oleate, Neopentyl Glycol Dicaprate, Triethyl Citrate, 2-Ethylhexyl Succinate, Amyl Acetate, Ethyl Acetate, Butyl Acetate, Isocetyl Stearate, Butyl Stearate, Diisopropyl Sebacate, Di-2-Ethylhexyl Sebacate, Cetyl Lactate, Myristyl Lactate, Isopropyl Palmitate, 2-Ethylhexyl Palmitate, 2-Hexyl Palmitate Examples of ester oils include undecyl palmitate, 2-heptylundecyl palmitate, cholesteryl 12-hydroxystearate, dipentaerythritol fatty acid esters, isopropyl myristate, octyldodecyl myristate, 2-hexyldecyl myristate, myristyl myristate, hexyldecyl dimethyloctanoate, ethyl laurate, hexyl laurate, 2-octyldodecyl N-lauroyl-L-glutamate, and diisostearyl malate.Further examples include glyceride oils such as acetoglyceride, triisooctanoic acid glyceride, triisostearic acid glyceride, triisopalmitic acid glyceride, tri-2-ethylhexanoic acid glyceride, monostearic acid glyceride, di-2-heptylundecanoic acid glyceride, trimyristate acid glyceride, and castor oil; higher alkoxy-modified silicones such as dimethylpolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, tetramethyltetrahydrogencyclotetrasiloxane, and stearoxysilicone; silicone-based oils such as higher fatty acid-modified silicones, silicone resins, silicone rubber, and silicone oil; and fluorine-based oils such as perfluoropolyether, perfluorodecalin, and perfluorooctane. Desirable examples include jojoba oil, castor oil, liquid paraffin, squalene, petrolatum, stearic acid, oleyl alcohol, and the like, and one or more of these may be used.

[0033] The pigment is not particularly limited, and may be a cosmetic powder used to impart special optical effects such as pearlescent luster, iridescent color, or metallic effect to an object to be colored, or to color, coat, protect against UV rays, prevent makeup from smearing by absorbing secreted sebum, or provide a smooth feel when used. More specifically, it may be, for example, a glitter or pearlescent pigment commonly used in topical skin makeup preparations such as lipstick, eye color, cheek color, or nail color, or in topical skin preparations for hair. These pigments are not particularly limited, and examples include lake pigments, organic pigments, colored pigments, white pigments, extender pigments, glass flake pigments, metal-coated inorganic pigments, pearlescent pigments, metallic luster pigments, resin pigments, and functional pigments, and one or more of these may be used.

[0034] There are two main types of lake pigments: one is a pigment insolubilized in water by converting a water-soluble dye into a salt such as calcium, and examples thereof include Red No. 202, 204, 206, 207, 208, and 220. The other is a pigment made water-insoluble with aluminum sulfate, zirconium sulfate, or the like and then adsorbed onto alumina, and examples thereof include Yellow No. 5 and Red No. 230.

[0035] Organic pigments are formed from colored powders that do not have hydrophilic groups in their molecular structure and are insoluble in water, oil, or solvents, and have excellent coloring power and lightfastness. Examples of organic pigments include, but are not limited to, the azo pigment Red No. 228, the indigo pigment Red No. 226, and the phthalocyanine pigment Blue No. 404.

[0036] The color pigment is not particularly limited, but examples thereof include iron oxides with different color tones, such as red iron oxide, yellow iron oxide, and black iron oxide, ultramarine, Prussian blue, chromium oxide, chromium hydroxide, magnesium oxide, cobalt oxide, cobalt titanate carbon black, manganese violet, and cobalt violet.

[0037] White pigments are mainly used for the purpose of coloring, coating, etc., and examples thereof include titanium dioxide, zinc oxide, etc. Extender pigments are mainly used to adjust the shape retention, extensibility, adhesion, gloss, etc. of products, and to adjust the color tone (diluent), rather than for coloring, and examples thereof include mica-based pigments such as mica, muscovite, synthetic mica, phlogopite, lepidolite, biotite, and lepidolite, clay minerals such as sericite, talc, kaolin, montmorillonite, and zeolite, and synthetic inorganic powders such as magnesium carbonate, calcium carbonate, silicic acid, silicic acid anhydride, aluminum silicate, magnesium silicate, aluminum magnesium silicate, sulfur-containing aluminum silicate, calcium silicate, barium silicate, strontium silicate, aluminum oxide, and barium sulfate.

[0038] Glass flake pigments are glass flakes whose surfaces are thinly coated with a metal or the like. Metal-coated inorganic pigments are inorganic pigments coated with a metal and / or metal oxide by metal vapor deposition or the like, and examples thereof include iron oxide-coated aluminum, iron oxide-coated mica, and aluminum-manganese-coated micaceous iron oxide. Pearlescent pigments are pigments used to impart special optical effects such as pearlescent luster, iridescent colors, and metallic finishes to objects to be colored, and examples thereof include titanium mica, titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, fish scale foil, and bismuth oxychloride. Metallic luster pigments are not particularly limited, and examples thereof include aluminum powder, gold powder, silver powder, copper powder, tin powder, and brass powder.

[0039] Resin pigments are thin flakes obtained by coloring and cutting resin films, and examples thereof include polyethylene powder, polymethyl methacrylate, polyethylene terephthalate-polymethyl methacrylate laminate powder, nylon powder polyester film powder, polyethylene terephthalate-aluminum-epoxy laminate film powder, polyethylene terephthalate-polyolefin laminate film powder, polyethylene terephthalate-polymethyl methacrylate laminate powder, etc. Functional pigments are not particularly limited, but examples thereof include boron nitride, synthetic fluorine phlogopite, photochromic pigments, composite fine particle powders, etc.

[0040] The form of the pigment is not particularly limited and may be selected as appropriate depending on the purpose and the powder used, such as granular, plate-like, or rod-like. The size of the powder is also not particularly limited and may be selected as appropriate depending on the purpose and the powder used. For example, granular powders typically have an average particle size of 0.01 to 10 μm, while flake- or rod-like powders typically have a length of 0.5 to 10 μm. The pigment content is selected as appropriate depending on the pigment used, but may be, for example, 0.01% by mass or more and 80% by mass or less based on the total amount of the topical skin preparation.

[0041] The type of surfactant is not particularly limited, and any of nonionic, anionic, cationic, and amphoteric surfactants may be used depending on the application, but surfactants with a hydrophilic-lipophilic ratio (HLB value) of 10 to 18 are preferably used.

[0042] Nonionic surfactants are not particularly limited, but examples thereof include polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, sorbitan fatty acid esters, polyoxyethylene glycerin fatty acid esters, glycerin fatty acid esters, polyglycerin fatty acid esters, polyoxyethylene hydrogenated castor oils, sucrose fatty acid esters, and ethylene oxide-propylene oxide block copolymers.

[0043] Specific examples of lipophilic nonionic surfactants include, but are not limited to, sorbitan fatty acid esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, and diglycerol sorbitan tetra-2-ethylhexylate; glycerin (or polyglycerin) fatty acid esters such as glycerin monocottonseed oil fatty acid, glycerin monoerucate, glycerin sesquioleate, glycerin monostearate, glycerin α,α'-oleic acid pyroglutamate, glycerin monostearate, and malic acid; propylene glycol fatty acid esters such as propylene glycol monostearate; hydrogenated castor oil derivatives; and glycerin alkyl ethers.

[0044] The hydrophilic nonionic surfactant is not particularly limited, and examples thereof include POE sorbitan monooleate (hereinafter, polyoxyethylene may be referred to as "POE"), POE sorbitan fatty acid esters such as POE-sorbitan monostearate, POE-sorbitan dioleate, and POE-sorbitan tetraoleate, POE sorbitan fatty acid esters such as POE-sorbitan monolaurate, POE-sorbit monooleate, POE-sorbitan pentaoleate, and POE-sorbit monostearate, POE-glycerin monostearate, and the like. POE glycerin fatty acid esters such as POE-glycerin monoisostearate and POE-glycerin triisostearate, POE fatty acid esters such as POE monooleate, POE distearate, POE dioleate and ethylene glycol distearate, POE alkyl ethers such as POE lauryl ether, POE oleyl ether, POE-stearyl ether, POE behenyl ether, POE 2-octyldodecyl ether and POE cholestanol ether, POE octylphenyl ether, POE nonylphenyl ether, PO POE alkyl phenyl ethers such as POE dinonylphenyl ether, POE·POP cetyl ether (hereinafter, polyoxypropylene will also be referred to as "POP"), POE·POP 2-decyltetradecyl ether, POE·POP monobutyl ether, POE·POP hydrogenated lanolin, POE·POP alkyl ethers such as POE·POP glycerin ether, POE·POP ethylenediamine condensates, POE castor oil, POE hydrogenated castor oil, POE hydrogenated castor oil monoisostearate, POE hydrogenated castor oil triisostearate, POE hydrogenated castor oil POE castor oil (or hydrogenated castor oil) derivatives such as oil monopyroglutamic acid monoisostearate diester, POE hydrogenated castor oil maleic acid, POE such as POE sorbitol beeswax, beeswax and lanolin derivatives, coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, alkanolamide such as fatty acid isopropanolamide, POE propylene glycol fatty acid ester, POE alkylamine, POE fatty acid amide, sucrose fatty acid ester, POE nonylphenyl formaldehyde condensate, alkylethoxydimethylamine oxide,trioleyl phosphate, etc.

[0045] The anionic surfactant is not particularly limited, but examples thereof include soap bases, fatty acid soaps such as sodium laurate and sodium palmitate, higher alkyl sulfates such as sodium lauryl sulfate and potassium lauryl sulfate, alkyl ether sulfates such as POE triethanolamine lauryl sulfate and POE sodium lauryl sulfate, N-acyl sarcosinates such as sodium lauroyl sarcosinate, higher fatty acid amide sulfonates such as sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl tauride and sodium lauryl methyl tauride, phosphate ester salts such as sodium POE oleyl ether phosphate and POE stearyl ether phosphate, sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, lauryl polypropylene glycol Examples of suitable sulfosuccinates include alkylbenzenesulfonates such as sodium linear dodecylbenzenesulfonate, linear dodecylbenzenesulfonic acid sodium salt, linear dodecylbenzenesulfonic acid triethanolamine salt, and linear dodecylbenzenesulfonic acid; N-acylglutamates such as monosodium N-lauroylglutamate, disodium N-stearoylglutamate, and monosodium N-myristoyl-L-glutamate; higher fatty acid ester sulfates such as hydrogenated coconut oil fatty acid glycerin sodium sulfate; sulfated oils such as turmeric oil; POE alkyl ether carboxylic acids; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfates; higher fatty acid alkylolamide sulfates; sodium lauroylmonoethanolamide succinate; N-palmitoyl aspartic acid ditriethanolamine; and sodium caseinate.

[0046] The cationic surfactant is not particularly limited, and examples thereof include alkyltrimethylammonium salts such as stearyltrimethylammonium chloride and lauryltrimethylammonium chloride, distearyldimethylammonium chloride, poly(N,N-dimethyl-3,5-methylenepiperidinium) chloride, alkylpyridinium salts such as cetylpyridinium chloride, alkyl quaternary ammonium salts, alkyldimethylbenzylammonium salts, alkylisoquinolinium salts, dialkylmorphonium salts, POE alkylamines, alkylamine salts, polyamine fatty acid derivatives, amyl alcohol fatty acid derivatives, benzalkonium chloride, benzethonium chloride, acrylic acid / β-NN dimethyl-N-ethylammonioethyl acid vinylpyrrolidone copolymers, and cationic polymer derivatives.

[0047] The amphoteric surfactant is not particularly limited, but examples thereof include imidazoline-based amphoteric surfactants such as 2-undecyl-N,N,N-(hydroxyethylcarboxymethyl)-2-imidazoline sodium and 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, and betaine-based surfactants such as 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amido betaine, and sulfobetaine. The content of the surfactant is not particularly limited, but may be, for example, 0.1% by mass or more and 10% by mass or less based on the total amount of the topical skin preparation.

[0048] The thickener is not particularly limited, but examples thereof include natural polymers such as gum arabic, guar gum, karaya gum, carrageenan, pectin, fucoidan, quince seed gum, tolant gum, locust bean gum, galactomannan, xanthan gum, curdlan, gellan gum, and fucogel; semi-synthetic polymers such as methyl cellulose, ethyl cellulose, methylhydroxypropyl cellulose, carboxymethyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, sodium carboxymethyl cellulose, and propylene glycol alginate; and synthetic polymers such as polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, polyacrylate, and polyethylene oxide; and inorganic minerals such as bentonite, laponite, and hectorite may also be used in combination.

[0049] The pigments are not particularly limited, but examples thereof include organic synthetic pigments such as azo dyes such as Yellow No. 5 and Red No. 505, xanthene dyes such as Red No. 213 and Red No. 230, quinoline dyes such as Yellow No. 204, triphenylmethene dyes such as Blue No. 1, anthraquinone dyes such as Green No. 201, indigo dyes, lake pigments such as Red No. 202 and Red No. 208, Red No. 228, Red No. 226, and Blue No. 404, and natural pigments such as carotene, carthamine, and cochineal.

[0050] The formulation form (dosage form) of the topical skin preparation of the present disclosure is not particularly limited, and may be, for example, an aqueous solution system, a solubilized system, various emulsion systems, a powder dispersion system, or the like.

[0051] The uses of the topical skin preparation of the present disclosure are not particularly limited, and may be used, for example, in basic cosmetics such as lotions, emulsions, creams, and packs, makeup cosmetics such as lipstick and foundation, hair products such as shampoos and conditioners, and specialized cosmetics such as sunscreens. [Example]

[0052] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples. Note that "%" means % by mass unless otherwise specified.

[0053] (material) The following materials were used to prepare the sample cosmetics of the Examples and Comparative Examples. The blending amounts below can be considered to be the same as the contents in the prepared sample cosmetics. <Component A in the Examples> A-1: Aloe vera leaf extract (trade name Biocellact® Aloe Vera B, manufactured by Ichimaru Pharcos Co., Ltd.), solid content 0.50% A-2: Aloe vera leaf extract (product name: Aloe Extract Vera Miyakojima, manufactured by Ichimaru Pharcos Co., Ltd.), solid content 0.30% A-3: Aloe vera leaf extract (product name: Aloe Vera Liquid BG Miyakojima, manufactured by Ichimaru Pharcos Co., Ltd.), solid content 0.30% A-4: Aloe arborescens leaf extract (trade name: Falcorex (registered trademark) Aloe KB, manufactured by Ichimaru Falcos Co., Ltd.), solid content 1.05% <Component B in the Examples> B-1X: Alcaligenes-produced polysaccharide X lot (trade name Alcasealan (registered trademark), manufactured by Hakuto Co., Ltd.) B-1Y: Alcaligenes-produced polysaccharide Y lot (trade name Alcasealan (registered trademark), manufactured by Hakuto Co., Ltd.)

[0054] In the comparative examples, the following component C was used in place of component B to prepare the test cosmetics. <Component C of Comparative Example> C-1: Locust bean gum (product name GENUGUM type RL-200-J, manufactured by CP Kelco) C-2: Hydroxypropyl guar gum (trade name JAGUAR HP-105, manufactured by Solvay USA Inc.) C-3: Sodium hyaluronate (trade name Hyaluronic Acid IW120, manufactured by Iwaki Pharmaceutical Co., Ltd.) C-4: Xanthan gum (trade name KELTROL CG, manufactured by CP Kelco) C-5: Carboxymethyl cellulose (trade name CMC Daicel, manufactured by Daicel Miraize Co., Ltd.) C-6: Polyvinyl alcohol (trade name J Poval VP-18, manufactured by Nippon Vaccination & Poval Co., Ltd.) C-7: Carbomer (trade name Hiviswako 105, manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.) C-8: Pullulan (product name: Cosmetic Pullulan, manufactured by Hayashibara Co., Ltd.)

[0055] Other details of the ingredients used (ingredient names, product names, manufacturer names) are shown below. Behenyl alcohol, NIKKOL Behenyl Alcohol 65, Nikko Chemicals Co., Ltd. Polyglyceryl-10 myristate, NIKKOL Decaglyn 1-M, Nikko Chemicals Co., Ltd. Triethylhexanoin, NIKKOL Trifat S-308, Nikko Chemicals Co., Ltd. Polyglyceryl-10 stearate, NIKKOL Decaglyn 1-SV, Nikko Chemicals Co., Ltd. Glyceryl stearate, NIKKOL MGS-F40V, Nikko Chemicals Co., Ltd. PEG-100 Hydrogenated Castor Oil, NIKKOL HCO-100, Nikko Chemicals Co., Ltd. Polyoxyethylene (20) oleyl ether, NIKKOL BO-20V, Nikko Chemicals Co., Ltd. POE(12) Monostearate, Nonion S-6, NOF Corporation Glyceryl monostearate, Monoglyceryl MB, NOF Corporation Stearic acid, NAA-180, NOF Corporation Myristic acid, NAA-102, NOF Corporation Lauric acid, NAA-122, NOF Corporation Polyethylene glycol 400, PEG#400, NOF Corporation Sorbitan monostearate, Nonion SP-60RP pellets, NOF Corporation Cetyl isooctanoate, FineNeo NS-CIO, Nippon Fine Chemical Co., Ltd. Diethylhexyl sebacate, FineNeo-EHS, Nippon Fine Chemical Co., Ltd. Lanolin, refined lanolin, Nippon Fine Chemical Co., Ltd. Liquid lanolin, Nippon Fine Chemical Co., Ltd. Isopropyl myristate, FineNeo-IPM, Nippon Fine Chemical Co., Ltd. 1,3-Butylene Glycol, 1,3-Butylene Glycol UK, Daicel Corporation 1,2-Pentanediol, Gerrn Pentanediol, Minasolve SAS Glycerin, concentrated glycerin for cosmetics, Kao Corporation Polysorbate 80, Rheodor TW-O120V, Kao Corporation Olive fruit oil, Kuropure OL, Croda Japan Co., Ltd. Sorbitan monooleate, SPAN 80, Croda Japan Co., Ltd. Polyoxyethylene sorbitan monostearate, TWEEN (registered trademark) 60, Croda Japan Co., Ltd. Glycerin Mono-2-Ethylhexyl Ether, Sensiva SC 50 JP Multifunctional, Ashland LLC Diglycerin, Diglycerin S, Sakamoto Pharmaceutical Co., Ltd. Phenoxyethanol, Phenoxyethanol-S, Yokkaichi Chemical Co., Ltd. Cetearyl Alcohol, Cetearyl Glucoside, Montanov 68 MB, SEPPIC SA Ethylhexyl palmitate, IOP, Kokyu Alcohol Kogyo Co., Ltd. Cetyl alcohol, Cetyl alcohol, Kokyu Alcohol Kogyo Co., Ltd. Cetearyl alcohol, cetostearyl alcohol, Kokyu Alcohol Kogyo Co., Ltd. Jojoba seed oil, refined jojoba oil, Koei Kogyo Co., Ltd. Partially hydrogenated jojoba oil, Jojoba Cream M-40, Koei Kogyo Co., Ltd. Tocopherol, Riken E Oil 700, Riken Vitamin Co., Ltd. Dimethicone, KF-96A-50cs, Shin-Etsu Chemical Co., Ltd. PEG-10 Dimethicone, KF-6017P, Shin-Etsu Chemical Co., Ltd. Squalane, vegetable squalane, Kishimoto Special Cod Liver Oil Industry Co., Ltd. Dipentaerythrityl hexahydroxystearate, Cosmol 168M, Nisshin Oillio Group Co., Ltd. Gelatin, COD GELATINE, MARINE COLLAGEN EHF. Neopentyl glycol diheptanoate, isododecane, LexFeel D4, INOLEX, Inc. Propylene glycol, propylene glycol, ADEKA Corporation Dipotassium glycyrrhizinate, Dipotassium glycyrrhizinate (external source), Maruzen Pharmaceutical Co., Ltd. Liquid paraffin, Moresco White P-80, MORESCO Corporation Bentonite, Kunipia-F, Kunimine Industries Co., Ltd. Montmorillonite, CosWHITE (White-Pinkish Clay), Argile du Velay Kaolin, Kaolin JP-100, Takehara Chemical Industry Co., Ltd. Sucrose myristate, Ryoto Sugar Ester M-1695, Mitsubishi Chemical Corporation Tocopherol acetate, dl-α-tocopherol acetate, DSM Co., Ltd. Isostearyl myristate, Esterol M-IS, National Mimatsu Co., Ltd. Arginine, L-Arginine C Grade, Ajinomoto Co., Inc. Acrylates / C10-30 Alkyl Acrylate Crosspolymer, Pemulen TR-1, Lubrizol Corporation Anhydrous citric acid, citric acid (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Trisodium citrate dihydrate, Trisodium citrate dihydrate (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Carbomer, Hiviswako 103, Fujifilm Wako Pure Chemical Industries, Ltd. Sodium hydroxide, sodium hydroxide (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Potassium hydroxide, potassium hydroxide (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Glycine, Glycine (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Cystine, L-cystine (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Phenylalanine, L-phenylalanine (special grade), Fujifilm Wako Pure Chemical Industries, Ltd. Ethanol, Ethanol (99.5), Fujifilm Wako Pure Chemical Industries, Ltd. Titanium dioxide (1), MT-100AQ, Teika Co., Ltd. Titanium dioxide (2), STR-100C-LP, Sakai Chemical Industry Co., Ltd. White pigment titanium dioxide (1), SYMPHOLIGHT WW-E, JGC Catalysts and Chemicals Co., Ltd. Red iron oxide (1), SYMPHOLIGHT RW-TE, JGC Catalysts and Chemicals Co., Ltd. Yellow iron oxide (1), SYMPHOLIGHT YW-TE, JGC Catalysts and Chemicals Co., Ltd. Black iron oxide (1), SYMPHOLIGHT BW-TE, JGC Catalysts and Chemicals Co., Ltd. White pigment titanium dioxide (2), ASL-1 TiO2CR-50, Daito Chemical Industry Co., Ltd. Yellow iron oxide (2), ASL-1 YELLOW LL-100P, Daito Chemical Industry Co., Ltd. Red iron oxide (2), ASL-1 RED R-516P, Daito Chemical Industry Co., Ltd. Black iron oxide (2), ASL-1 BLACK BL-100P, Daito Chemical Industry Co., Ltd.

[0056] (Measurement of the average molecular weight of component B) The molecular weights of B components B-1X and B-1Y were determined as follows. First, a test sample (B-1X X lot) and pullulan (Shodex SATNDARD P-82, manufactured by Resonac Corporation, P-800 (molecular weight 788,000), P-400 (molecular weight 404,000), and P-200 (molecular weight 212,000)) were dispersed in 200 ppm, 150 ppm, and 100 ppm 1N sodium nitrate solutions, respectively. Each sample was then measured three times at 37.7°C using an Ubbelohde viscometer (Ubbelohde viscometer (Type 0, Type 0C)) to determine the kinematic viscosity. The same measurements were performed on B component B-1Y to determine its kinematic viscosity. The intrinsic viscosity was calculated using the calculated kinematic viscosity according to the following equation. A calibration curve was drawn from the intrinsic viscosity of pullulan. In the following formula, [η] represents the intrinsic viscosity, A represents the slope (constant), η represents the kinematic viscosity, η0 represents the kinematic viscosity of a 1N sodium nitrate solution, and c represents the concentration. (η rel -1) / c=[η]+Ac η rel =η / η0

[0057] Figure 1 is an explanatory diagram showing the intrinsic viscosity of the test sample (B-1X X lot). Figure 2 is an explanatory diagram showing the calibration curve obtained from the intrinsic viscosity of pullulan. In Figure 1, the vertical axis represents the intrinsic viscosity, and the horizontal axis represents the concentration (%). In Figure 2, the vertical axis represents the intrinsic viscosity, and the horizontal axis represents the molecular weight. From Figures 1 and 2, the average molecular weight of the test sample (B-1X X lot) was calculated using pullulan as the standard. The intrinsic viscosity of the test sample (B-1X X lot) was 9.9028. When this was substituted into the calibration curve formula (y = 0.0211x - 0.246), the average molecular weight of the test sample (B-1X X lot) using pullulan as the standard was calculated to be 4.6 x 10 6 Similarly, the average molecular weight of the test sample (B-1Y Y lot) based on pullulan was 1.5 × 10 7 It was.

[0058] (Evaluation test of moisturizing effect and stickiness) Test lotions were prepared according to the following formulations for Examples 1 to 15 and Comparative Examples 1 to 10, and the moisturizing effect and sticky feeling were evaluated using these. The test environment was maintained at a temperature of 25°C and a humidity of 50% during the test period.

[0059] (1) Preparation of test lotion Test lotions were prepared with the formulations of Component A and Component B or C shown in Table 1 below. The other formulations were the same as above, as follows: The "control" of Comparative Example 9 was a formulation in which Component A and Component B or C were replaced with purified water, and the "blank" of Comparative Example 10 was purified water. 1,3-butylene glycol 5.00% 1,2-Pentanediol 3.00% Glycerin 2.00% Glycerin mono-2-ethylhexyl ether 0.20% Purified water, the balance based on the total amount being 100%

[0060] Test lotions were prepared using the following method. Component B or C was kneaded with BG and stirred using a three-one motor. Purified water was added to the mixture to obtain Dispersion 1. 1,3-butylene glycol, 1,2-pentanediol, glycerin, glycerin mono-2-ethylhexyl ether, and purified water were mixed to obtain Mixture 1. Dispersion 1 was added to Mixture 1 and heated to 80°C to dissolve, obtaining Dispersion 2. Dispersion 2 was stirred at 8000 rpm for 10 minutes using a homogenizer (a homogenizer combining a PRIMIX Corporation MARK II homomixer with a Lab-lution main unit) while maintaining the temperature at 80°C, and then cooled to 40°C. Component A was then added to prepare the test lotions of Examples 1 to 15 and Comparative Examples 1 to 8. The test lotion of Comparative Example 9 was prepared in the same manner, except that purified water was used instead of Component A and Component B or C. In Comparative Example 10, purified water was used as is.

[0061] (2) Evaluation test method (2-1) Moisturizing effect (moisturizing power and long-lasting moisture retention) This test involved five panelists (N=5). The moisturizing effect was evaluated based on the change in moisture content of the panelists' skin, measured as electrical conductivity. That is, the higher the measured electrical conductivity, the higher the moisture content of the skin and the greater the moisturizing effect. For the measurement, the panelists' lower arms were first thoroughly washed with soap and left as is for 20 minutes. After 20 minutes of washing, the moisture content of the skin was measured as electrical conductivity (μS / cm) using a SKICON-200EX (manufactured by Yayoi Co., Ltd.). This was taken as the initial value of electrical conductivity at the start of the test (0 minutes). Immediately afterwards, 0.05 ml of the test lotion was applied to a 2 cm x 2 cm area of ​​the panelists' lower arms. Sixty minutes after application of the lotion, the moisture content of the skin was measured as electrical conductivity (μS / cm) using a SKICON-200EX. The average of the electrical conductivity measurements of the five panelists was calculated, and the moisturizing properties were evaluated using the electrical conductivity 60 minutes after application of the test lotion according to the following evaluation criteria.

[0062] <Moisturizing effect 60 minutes after application of test lotion> ◎: Electrical conductivity is more than five times the initial value ○: Electrical conductivity is 4 to 5 times the initial value △: Electrical conductivity is between 3 times and 4 times the initial value ×: Electrical conductivity is less than three times the initial value

[0063] (2-2) Stickiness The five panelists evaluated the stickiness of the lotion (stickiness 20 minutes after application of the test lotion) through a sensory evaluation according to the following evaluation criteria. The sensory evaluation was conducted after each panelist agreed to the following evaluation criteria, and the evaluation results were then decided through discussion among the five panelists.

[0064] <Stickiness 20 minutes after applying the test lotion> ◎: No stickiness ○: Slightly sticky △: Slightly sticky ×: Very sticky

[0065] (result) The evaluation results are shown in Table 1 below.

[0066] [Table 1]

[0067] It was found that topical skin preparations containing components A and B have superior moisturizing effects (moisturizing properties and sustained moisturizing properties) and can suppress sticky feelings compared to topical skin preparations containing component C instead of component B. It was also found that topical skin preparations containing 0.1% to less than 4.0% by mass of component A and 0.05% to 1.0% by mass of component B, relative to the total amount of the topical skin preparation, are superior in terms of moisturizing properties and sticky feelings.

[0068] External preparations for skin were prepared for the following Examples 16 to 29 and Comparative Examples 11 and 12. The formulations and preparation methods of the external preparations for skin are shown below.

[0069] (Example 16) Emulsion 1 1.A-1 4.00% 2.B-1X 0.1% 3. 1,2-Pentanediol 3.50% 4. Glycerin 5.00% 5. Diglycerin 2.00% 6. Phenoxyethanol 0.90% 7. Cetearyl alcohol, cetearyl glucoside 0.6% 8. Behenyl alcohol 0.30% 9. Polyglyceryl-10 Myristate 0.15% 10. Triethylhexanoin 1.00% 11. Jojoba seed oil 0.90% 12. Tocopherol 0.02% 13. Anhydrous citric acid 0.005% 14. Trisodium citrate dihydrate 0.04% 15. Purified water (remaining amount to make 100%)

[0070] Ingredients Nos. 1 to 6 and 15 were mixed while heating to 70°C and stirring to prepare Mixture 1. Similarly, ingredients Nos. 7 to 12 were mixed while heating to 70°C to prepare Mixture 2. Mixture 2 was added to Mixture 1 while stirring at 8000 rpm using a homomixer to prepare an emulsion. The mixture was then cooled to room temperature with stirring using a propeller stirrer, and Nos. 13 and 14 were added while stirring at 50°C to obtain Emulsion 1 (Example 16).

[0071] (Example 17) Cream 1 1.A-1 5.00% 2.B-1X 0.08% 3.1,3-Butylene glycol 8.00% 4. Glycerin 5.00% 5. Phenoxyethanol 0.90% 6. Polyglyceryl-10 stearate 0.40% 7. Jojoba seed oil 2.00% 8. Squalane 10.00% 9. Olive fruit oil 3.00% 10. Behenyl alcohol 4.00% 11. Partially hydrogenated jojoba oil 0.50% 12. Glyceryl stearate 0.50% 13. Tocopherol 0.05% 14. Carbomer 0.30% 15.Purified water 14.7% 16. Sodium hydroxide 0.02% 17.Purified water 10.0% 18. Purified water (remaining amount to make 100%)

[0072] Ingredients No. 14 and 15 were pre-dispersed in water using a Disper (a Disper combining a Homodisper 2.5-type blade with a main body laboratory solution) (Dispersion 1). Ingredients No. 1 to 6 and 18 were weighed and dissolved by heating at 80°C (Mixture 1). Ingredients No. 7 to 13 were weighed and dissolved by heating at 80°C (Mixture 2). While stirring Mixture 1 at 8000 rpm with a homogenizer (or homomixer), Mixture 2 was gradually added, and stirring was continued for 10 minutes after the addition (Emulsion 1). Emulsion 1 was cooled to room temperature, Dispersion 1 was added, and the mixture was neutralized with ingredients 16 and 17 to obtain Cream 1 (Example 17).

[0073] (Example 18) Cream 2 1. POE(12) Monostearate 2.00% 2. Glyceryl monostearate 5.00% 3. Dimethicone 1.50% 4. Stearic acid 5.00% 5. Squalane 15.0% 1,3-butylene glycol 5.00% 6. Cetyl isooctanoate 5.00% 7. Glycerin mono-2-ethylhexyl ether 0.20% 8. Glycerin 5.00% 9.C-3 0.01% 10.B-1X 0.05% 11.A-1 3.00% 12. Titanium dioxide (1) 2.00% 13. Purified water (remaining amount to make 100%)

[0074] Ingredients Nos. 1 to 3 were heated and mixed, and the mixture was kept at 70°C to form Mixture 1. Ingredients Nos. 7 to 9 and a portion of No. 13 were heated and mixed, and the mixture was kept at 70°C to form Mixture 2. Mixture 2 was added to Mixture 1 while stirring it with a homomixer to prepare a W / O type emulsion, which was formed as Emulsion 1. Ingredients Nos. 4 to 6 were heated and mixed, and the mixture was kept at 70°C to form Mixture 3. While stirring and mixing the remaining ingredients 10, 11, and 13, Emulsion 1, Mixture 3, and Ingredient No. 12 were added in that order, and the mixture was mixed uniformly to obtain W / O / W multiple emulsion cream 2 (Example 18).

[0075] (Example 19) Cream 3 1. Dimethicone 1.50% 2. Diethylhexyl sebacate 15.0% 3. Glycerin 10.00% 4. PEG-100 Hydrogenated Castor Oil 1.00% 5. Glycerin mono-2-ethylhexyl ether 0.20% 6.C-3 0.04% 7. Gelatin 0.80% 8.A-1 3.50% 9. 1,3-Butylene Glycol 5.00% 10.B-1X 0.05% 11. Purified water (remaining amount to make 100%) 12. PEG-10 Dimethicone 1.00% 13. Neopentyl glycol diheptanoate, isododecane 49.0%

[0076] Ingredients Nos. 3 to 5 were mixed until uniform to prepare mixture 1, and ingredients Nos. 1 and 2 were mixed until uniform to prepare mixture 2. Mixture 1 was gradually added to mixture 2 to prepare mixture 3. Furthermore, a portion of No. 9, 10, and 11 were dispersed using a three-one motor to prepare dispersion 1, and ingredients 6 to 9 were mixed, dispersion 1 was added, and the mixture was heated and mixed. After maintaining the temperature at 50°C, mixture 4 was prepared. Mixture 3 was added to mixture 4 while stirring, to prepare O / W microcapsules. Furthermore, ingredients 12 and 13 were mixed until uniform, and O / W microcapsules were added to this to obtain O / W / O cream 3 (Example 19).

[0077] (Example 20) Facial Cleanser 1 1. Myristic acid 18.0% 2. Stearic acid 8.00% 3. Lauric acid 5.00% 4. Potassium hydroxide 5.50% 5. Glycerin 5.00% 6. Diglycerin 3.00% 7. Polyoxyethylene (20) sorbitan oleate 4.00% 8. Propylene glycol 10.0% 9. Glycerin mono-2-ethylhexyl ether 0.25% 10.B-1X 0.05% 11. Dipotassium glycyrrhizinate 0.05% 12. Purified water (remaining amount to make 100%) 13.A-1 3.00%

[0078] Ingredients Nos. 1 to 3 were heated and dissolved at approximately 70°C to prepare Mixture 1. Ingredients Nos. 5 to 9 were mixed with stirring to prepare Mixture 2. Next, Ingredients Nos. 4 and 11 were dissolved in Ingredient No. 12 heated to 70°C, and while stirring at 5,000 rpm with a homomixer, Ingredient No. 10 was added. After further dissolution at 70°C for 10 minutes, Mixture 1 was added and stirred for another 10 minutes to prepare an emulsion. This emulsion was stirred while cooling, and Mixtures 2 and 13 were added at approximately 40°C to obtain Facial Cleanser 1 (Example 20).

[0079] (Example 21) Cleansing 1 1.B-1X 0.05% 2. Glycerin 5.00% 3.1,3-Butylene glycol 5.50% 4. Phenoxyethanol 0.50% 5. Polyglyceryl-10 Stearate 2.50% 6. Carbomer 0.05% (105) 7. Purified water (remaining amount to make 100%) 8. Ethylhexyl palmitate 50.0% 9. Tocopherol 0.02% 10. Sodium hydroxide 0.001% 11.A-1 4.00%

[0080] Mixture 1 was prepared by dissolving ingredient Nos. 8 and 9 under heating. Ingredients Nos. 1 to 7 were heated, and while stirring at 5,000 rpm with a homomixer, Mixture 1 was added and stirred for 10 minutes. Mixture 2, in which a portion of ingredient No. 7 and No. 10 were dissolved, was then added and cooled. Ingredient No. 11 was added at approximately 40°C to obtain Cleansing 1 (Example 21).

[0081] (Example 22) Cleansing 2 1. Liquid paraffin 30.0% 2. Jojoba seed oil 15.0% 3. Sorbitan monooleate 2.00% 4. Lanolin 4.00% 5. Glycerin 6.00% 6. Propylene glycol 4.00% 7. Glycerin mono-2-ethylhexyl ether 0.30% 8.B-1X 0.06% 9. Purified water (remaining amount to make 100%) 10.A-1 4.00%

[0082] Ingredients Nos. 1 to 4 were heated and dissolved at approximately 70°C to prepare mixture 1. Ingredients Nos. 5 to 7 and Nos. 8 and 9 were separately stirred and dissolved at approximately 70°C, and then the two were mixed to prepare mixture 2. Mixture 2 was added to mixture 1 while stirring, and the mixture was stirred while cooling, and then ingredient No. 10 was added at approximately 40°C to obtain cleansing 2 (Example 22).

[0083] (Example 23) Pack 1 1.B-1X 0.08% 2.A-1 3.50% 3. Bentonite 5.00% 4. Montmorillonite 2.00% 5. Kaolin 5.00% 6. Glycine 0.50% 7. Cystine 0.50% 8. Phenylalanine 0.50% 9. Diglycerin 1.00% 10. Propylene Glycol 6.00% 11. Ethanol 6.00% 12. Sucrose myristate ester 0.50% 13. Glycerin mono-2-ethylhexyl ether 0.30% 14. Purified water (remaining amount to make 100%)

[0084] Ingredients Nos. 1 to 5 were added in order to ingredient No. 14 and stirred until uniform, to prepare mixture 1. Ingredients Nos. 6 to 13 were stirred and mixed to prepare mixture 2. While stirring mixture 1, mixture 2 was added and stirred until uniform, to prepare pack 1 (Example 23).

[0085] (Example 24) Gel 1 1.B-1X 0.05% 2. Carbomer 0.30% 3. Polyethylene glycol 400 3.00% 4. Glycerin 8.00% 5. Diglycerin 1.00% 6. Polyoxyethylene (20) oleyl ether 0.50% 7. Glycerin mono-2-ethylhexyl ether 0.30% 8. Tocopheryl acetate 0.03% 9.A-1 4.00% 10. Purified water (remaining amount to make 100%)

[0086] Ingredients Nos. 1 to 3 were added to ingredient No. 10 and stirred and mixed at 70°C until uniform, to prepare mixture 1. Ingredients Nos. 4 to 8 were stirred and mixed to prepare mixture 2. While stirring mixture 1, mixture 2 was added and stirred until uniform, and ingredient No. 9 was added and stirred to obtain gel 1 (Example 24).

[0087] (Example 25) Hair Treatment 1 1. Liquid lanolin 20.0% 2. Liquid paraffin 10.0% 3. Isopropyl myristate 8.00% 4. Cetyl alcohol 5.00% 5. Sorbitan monostearate 1.50% 6. Polyoxyethylene sorbitan monostearate 2.00% 7. Glycerin 5.00% 8. Glycerin mono-2-ethylhexyl ether 0.30% 9. Diglycerin 1.00% 10. Citric acid 0.10% 11. Sodium citrate 0.06% 12.B-1X 0.03% 13. Purified water (remaining amount to make 100%) 14.A-1 3.50%

[0088] Ingredients Nos. 1 to 5 were mixed to form Mixture 1, and ingredients 12 and 13 were previously dispersed using a disper to form Dispersion 1. Ingredients Nos. 6 to 11 were combined to form Mixture 2, and Dispersion 1 was added to Mixture 2. Each mixture was heated to 75°C, and then, while maintaining this temperature, Mixture 1 was gradually added while stirring with a propeller stirrer to prepare an emulsion. While stirring and cooling this emulsion, ingredient No. 14 was added, and Hair Treatment 1 (Example 25) was obtained.

[0089] (Example 26) Sunscreen 1 1. Glycerin 6.00% 2. Propylene glycol 5.00% 3. Glycerin mono-2-ethylhexyl ether 0.30% 4. Diglycerin 1.00% 5. Titanium dioxide (1) 8.00% 6. Cetearyl Alcohol 4.00% 7. Dimethylpolysiloxane KF-96A-50cs 2.00% 8. Isostearyl Myristate Esterol M-IS (National Mimatsu) 1.00% 9. Squalane 6.00% 10. Olive fruit oil 3.00% 11. Liquid paraffin 1.00% 12.B-1X 0.06% 13.A-1 3.50% 14. Purified water (remaining amount to make 100%)

[0090] Ingredients Nos. 1 to 5 were mixed to form Mixture 1, and Ingredients Nos. 6 to 11 were mixed to form Mixture 2, and each was heated to 80°C. Ingredients Nos. 12 and 14 were mixed and heated to 80°C, and then dissolved for 10 minutes at 8,000 rpm in a homogenizer to form Mixture 3. Next, Mixture 1 was gradually added to Mixture 3 while the homogenizer was running at 8,000 rpm. After a further 10 minutes, Mixture 2 was gradually added and maintained for 10 minutes to prepare an emulsion. While stirring and cooling this emulsion, Ingredient No. 13 was added to prepare Sunscreen 1 (Example 26).

[0091] (Example 27) Sunscreen 2 1. Glycerin 6.00% 2. Propylene glycol 6.00% 3. Phenoxyethanol 0.50% 4. Titanium dioxide (2) 8.00% 5. Behenyl alcohol 4.00% 6. Glyceryl stearate 0.75% 7. Tocopherol 0.05% 8. (Acrylates / C10-30 alkyl acrylate) crosspolymer 0.02% 9.B-1X 0.06% 10. Purified water (remaining amount to make 100%) 11. Arginine 0.07% 12.A-1 4.00%

[0092] Ingredients Nos. 1 to 3 were mixed and heated to 80°C to form Mixture 1. Ingredients Nos. 5 to 7 were heated to 80°C, and to this was added ingredient 4 while stirring with a disperser to form Mixture 2. A portion of ingredients 9 and 10 were mixed and heated to 80°C, and then dissolved for 10 minutes at 8,000 rpm in a homogenizer or homomixer to form Mixture 3. Next, while stirring at 8,000 rpm in a homogenizer or homomixer, Mixture 1 was gradually added to Mixture 3, and after a further 10 minutes, Mixture 2 was gradually added. This mixture was maintained for 10 minutes to prepare Emulsion 1. After cooling this emulsion to 40°C with stirring, Mixture 4, in which ingredients Nos. 8 and 9 had been previously mixed and dispersed, was added to Emulsion 1 and paddle-stirred. Mixture 5, in which ingredients Nos. 11 and the remainder of 10 had been previously mixed, and ingredient No. 12 were added, and further stirring yielded Sunscreen 2 (Example 27).

[0093] (Example 28) Foundation 1 1. Glycerin 8.00% 2. Propylene glycol 7.00% 3. Glycerin mono-2-ethylhexyl ether 0.30% 4. Titanium dioxide (1) 5.00% 5. Pigment Titanium Dioxide (1) 5.00% 6. Red iron oxide (1) 0.12% 7. Yellow iron oxide (1) 0.70% 8. Black iron oxide (1) 0.05% 9.B-1X 0.06% 10. Purified water (remaining amount to make 100%) 11. Behenyl Alcohol 4.00% 12. Glyceryl stearate 0.75% 13. Olive Fruit Oil 3.00% 14. Squalane 7.00% 15. Tocopherol 0.05% 16. Dimethicone 2.00% 17. Dipentaerythrityl hexahydroxystearate 1.00% 18. Carbomer 0.08% 19.A-1 4.00%

[0094] Mixture 1 was prepared by mixing and heating ingredients Nos. 1-3 to a mixture heated to 80°C, to which ingredients Nos. 4-8 were added while stirring with a disperser. Mixture 1 was prepared by mixing a portion of ingredients Nos. 9 and 10 and heating to 80°C, followed by dissolving for 10 minutes at 8,000 rpm in a homogenizer or homomixer. Mixture 2 was prepared by mixing ingredients Nos. 11-17 and heating to 80°C. Mixture 3 was prepared by mixing and heating mixture 2 at 8,000 rpm in a homogenizer or homomixer. Mixture 1 was then gradually added to mixture 2, and after a further 10 minutes, mixture 3 was gradually added. This emulsion was then cooled to 40°C with stirring, and mixture 4, in which ingredients Nos. 18 and 10 had been previously dispersed, was then added to emulsion 1, followed by paddle stirring. Component No. 19 was added and further stirring was performed to obtain foundation 1 (Example 28).

[0095] (Example 29) Foundation 2 1. Glycerin 6.00% 2.1,3-Butylene glycol 8.00% 3. Phenoxyethanol 0.50% 4. White pigment titanium dioxide (2) 8.50% 5. Yellow iron oxide (2) 1.00% 6. Red iron oxide (2) 0.30% 7. Black iron oxide (2) 0.20% 8. Triethylhexanoin 22.0% 9. Behenyl alcohol 4.00% 10. Glyceryl stearate 0.75% 11. Tocopherol 0.05% 12.B-1X 0.06% 13. Purified water (remaining amount to make 100%) 14.A-1 4.00%

[0096] Mixture 1 was prepared by mixing a portion of ingredient Nos. 12 and 13, followed by mixing ingredient Nos. 1 to 3. Mixture 2 was prepared by adding ingredient Nos. 4 to 7 to ingredient Nos. 8 to 11 heated to 80°C while stirring with a disperser. Mixture 1 was heated to 80°C and then dissolved for 10 minutes at 8,000 rpm in a homogenizer or homomixer to prepare mixture 3. Mixture 2 was then gradually added to mixture 3 while stirring at 8,000 rpm in a homogenizer or homomixer, and the mixture was maintained for 10 minutes to prepare emulsion 1. This emulsion was cooled to 40°C while stirring, and then ingredient No. 14 was added to obtain foundation 2 (Example 29).

[0097] The emulsion of Comparative Example 11 was prepared in the same manner as in Example 16, except that No. 1 (Component A) and No. 2 (Component B) of Example 16 were replaced with purified water. The cream of Comparative Example 12 was prepared in the same manner as in Example 17, except that No. 1 (Component A) of Example 17 was replaced with the same amount of purified water.

[0098] The moisturizing effect and sticky feeling of each preparation of Examples 16 to 29 and Comparative Examples 11 and 12 were evaluated in the same manner as in Examples 1 to 15 and Comparative Examples 1 to 10. The results are shown in Table 2.

[0099] [Table 2]

[0100] The topical skin preparations of Examples 16 to 29 had superior moisturizing properties and reduced stickiness compared to the topical skin preparations of Comparative Examples 11 and 12. This demonstrates that the remarkable effects of the present invention can be obtained in various forms (dosage forms) of topical skin preparations and in various uses of topical skin preparations.

[0101] The present invention is not limited to the above-described embodiments and can be realized in various configurations without departing from the spirit of the present invention. For example, the technical features in the embodiments and examples corresponding to the technical features in each aspect described in the Summary of the Invention section can be appropriately replaced or combined to solve some or all of the above-described problems or achieve some or all of the above-described effects. Furthermore, if a technical feature is not described as essential in this specification, it can be deleted as appropriate. [Industrial Applicability]

[0102] The topical skin preparation of the present disclosure can be used as a topical skin preparation that has a high moisturizing effect and reduces stickiness.

Claims

1. An external preparation for skin, (A) an aloe extract; (B) a polysaccharide; Including, The polysaccharide (B) contains a structural unit represented by the following formula (1): External preparation for skin. 【Chemical 1】

2. The topical skin preparation according to claim 1, the content of the aloe extract (A) is 0.10% by mass or more and 10.0% by mass or less based on the total amount of the topical skin preparation, The content of the polysaccharide (B) is 0.01% by mass or more and 1% by mass or less based on the total amount of the topical preparation for skin. External preparation for skin.

3. The topical skin preparation according to claim 1 or 2, The average molecular weight of the polysaccharide (B) is 10 ６ That's all. External preparation for skin.

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