Oral composition

Abstract

To provide an oral composition that allows stable incorporation of a coffee oil component extract and that is environmentally considerate.SOLUTION: The oral composition according to the present invention contains (A) a coffee oil component extract obtained from coffee grounds after extraction and (B) a nonionic surfactant. The nonionic surfactant is preferably polyoxyethylene hydrogenated castor oil and / or a glycerin fatty acid ester. The oral composition preferably further contains (C) an anionic water-soluble polymer. The oral composition preferably further contains (D) an abrasive. The content of the coffee oil component extract is preferably 0.01 to 10 mass%.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an oral composition. [Background technology]

[0002] In recent years, there has been a demand for the development of cosmetics and oral preparations that incorporate naturally derived ingredients and that also take into consideration their impact on the environment. Upcycled raw materials made from recycled coffee grounds are environmentally friendly, and coffee oil extracts made from extracted coffee grounds are known to be incorporated into cosmetics (for example, Patent Document 1).

[0003] On the other hand, periodontal disease is a disease in which inflammation of the gums is caused by pathogenic bacteria. It is known that when gingival tissue is damaged by oxidative stress caused by inflammation, the destruction of collagen fibers and the decrease in cell proliferation ability cause gingival recession and the progression of periodontal disease. In addition, oral compositions are known that contain antioxidants and have a high periodontal disease prevention effect by eliminating active oxygen within cells that constitute the gingiva for a long period of time (for example, Patent Document 2). [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Publication No. 2023-112820 [Patent Document 2] International Publication No. 2014 / 073490 Summary of the Invention [Problem to be solved by the invention]

[0005] Coffee oil extracts are known to have useful antioxidant properties (Patent Document 1), and are expected to contribute to the prevention of periodontal disease in oral preparations. However, the coffee oil extracts are highly lipophilic, which poses a problem of reducing the stability of oral compositions when incorporated therein.

[0006] Therefore, an object of the present invention is to provide an oral composition that contains a stable coffee oil extract and is environmentally friendly. [Means for solving the problem]

[0007] The oral composition according to the present invention comprises (A) a coffee oil component extract obtained from extracted coffee grounds, and (B) a nonionic surfactant. [Effects of the Invention]

[0008] According to the present invention, it is possible to provide an oral composition that contains a stable coffee oil component extract and is environmentally friendly. DETAILED DESCRIPTION OF THE INVENTION

[0009] Preferred embodiments of the oral composition of the present invention will be described in detail below. The oral composition in this specification includes dentifrices such as toothpaste, lubricant toothpaste, powder toothpaste, liquid toothpaste, and liquid toothpaste, as well as lozenges, tablets, creams, ointments, patches, mouthwashes, and chewing gums. Of these, the oral composition of the present invention is preferably applied to toothpaste.

[0010] The oral composition of the present invention contains (A) a coffee oil component extract and (B) a nonionic surfactant. This makes it possible to provide an oral composition that stably incorporates a coffee extract and is also environmentally friendly.

[0011] <(A) Coffee oil extract> The oral composition of the present invention contains a coffee oil component extract as component (A). The coffee oil component extract is an extract obtained from extracted coffee grounds, specifically, by drying the coffee grounds after coffee extraction and extracting them with a solvent. More specifically, the coffee oil component extract can be obtained by the method disclosed in JP 2023-112820 A, for example. Examples of the types of coffee beans that are the source of coffee powder include Arabica, Robusta, Liberica, Arabusta, etc. Extraction solvents can be used regardless of their origin, such as animal oil, vegetable oil, or synthetic oil, or their type, such as solid oil, semi-solid oil, liquid oil, or volatile oil, and examples of such solvents include hydrocarbons, oils and fats, waxes, hardened oils, ester oils and triglycerides, fatty acids, higher alcohols, and silicone oils. Specifically, hydrocarbons such as liquid paraffin, olefin oligomer, squalane, polybutene, paraffin wax, ceresin wax, microcrystalline wax, Japan wax, and petrolatum; isostearyl isostearate, cholesteryl isostearate, isocetyl isostearate, isopropyl isostearate, isopropyl myristate, octyldodecyl myristate, polyglycerin fatty acid esters, hexyl laurate, isononyl isononanoate, trimethylolpropane triisostearate, ethyl oleate, ethyl linoleate, isocetyl stearate, isopropyl palmitate, diisopropyl dimerate, diisostearyl malate, neopentyl glycol dicaprate, hexyldecyl dimethyloctanoate, octyldodecyl dimethyloctanoate, cetyl 2-ethylhexanoate, and octyl palmitate, which are liquid at room temperature; Examples of suitable oils include ester oils and triglycerides such as di(cholesteryl, octyldodecyl) N-lauroyl-L-glutamate, triethylhexanoin, and tri(caprylic / capric)glyceryl; waxes such as beeswax, carnauba wax, candelilla wax, and bayberry; animal and vegetable oils such as refined oils or hydrogenated (hydrogenated) oils such as avocado oil, olive oil, safflower oil, jojoba oil, macadamia nut oil, palm oil, castor oil, sunflower oil, meadowfoam oil, hydrogenated castor oil, shea butter, lanolin, and fish oil; fatty acids such as stearic acid, isostearic acid, oleic acid, linoleic acid, and myristic acid; higher alcohols such as cetyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, and jojoba alcohol; and silicone oils such as methylpolysiloxane and decamethylcyclopentasiloxane. These may be used singly or in combination. The antioxidant effects of coffee oil extract can prevent and improve periodontal disease. In addition, since the coffee oil extract is extracted from coffee grounds after brewing, it reuses materials that would otherwise be discarded, reducing the burden on the environment.

[0012] The content of the coffee oil component extract is preferably 0.01 to 10% by mass, more preferably 0.05 to 5% by mass, and even more preferably 0.1 to 3% by mass, which allows the oral composition to efficiently exert good effects in preventing and improving periodontal disease while maintaining formulation stability as a whole. The content of coffee oil-derived components in the coffee oil component extract is preferably 0.5% by mass or more, more preferably 0.5 to 20% by mass, and even more preferably 1 to 10% by mass.

[0013] <(B) Nonionic surfactant> The oral composition of the present invention preferably contains a nonionic surfactant as component (B). The nonionic surfactant functions as a solubilizer, allowing the coffee oil extract to be more stably incorporated into the oral composition.

[0014] Examples of nonionic surfactants include sucrose fatty acid esters, maltose fatty acid esters, maltitol fatty acid esters, lactol fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan monostearate, polyoxyethylene higher alcohol ethers, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene copolymers, polyoxyethylene polyoxypropylene fatty acid esters, and polyglycerin fatty acid esters. Among these, polyoxyethylene hydrogenated castor oil and / or glycerin fatty acid esters are preferably used as the nonionic surfactant. This allows for more stable blending of the coffee oil component extract.

[0015] The content of the nonionic surfactant is preferably 0.005 to 20% by mass, more preferably 0.01 to 10% by mass, and even more preferably 0.1 to 5% by mass, which allows the coffee oil component extract to be blended more efficiently and stably while maintaining a good feel when used. When the content of the coffee oil component extract is taken as 1, the content of the nonionic surfactant is preferably 0.0005 to 2000, more preferably 0.002 to 200, and even more preferably 0.03 to 50.

[0016] <(C) Anionic water-soluble polymer> The oral composition of the present invention preferably contains an anionic water-soluble polymer, which improves the feel of the oral composition when used and improves the dispersibility of the coffee oil extract in the oral composition.

[0017] Although there are no particular limitations on the anionic water-soluble polymer, it is preferable to use at least one selected from the group consisting of cellulose gum, xanthan gum, carrageenan (ι, λ, κ), alginic acid, sodium alginate, potassium alginate, sodium polyacrylate, and carbomer, which can further improve the dispersibility of the coffee oil component extract.

[0018] The content of the anionic water-soluble polymer is preferably 0.1 to 10% by mass, more preferably 0.3 to 5% by mass, and even more preferably 0.5 to 2% by mass, which allows for more efficient improvement of the dispersibility of the coffee oil component extract. When the content of the coffee oil component extract is taken as 1, the content of the anionic water-soluble polymer is preferably 0.01 to 1000, more preferably 0.06 to 100, and even more preferably 0.16 to 20.

[0019] <(D) Abrasives> The oral composition of the present invention preferably contains an abrasive as component (D), which allows the coffee oil component extract to be incorporated more stably into the oral composition.

[0020] The abrasive is not particularly limited, but is preferably at least one selected from the group consisting of silica-based abrasives such as silicic acid anhydride, calcium phosphate, calcium carbonate, zeolite, silica gel, precipitated silica, pyrogenic silica, aluminosilicate, and zirconosilicate, calcium pyrophosphate, magnesium phosphate tribasic, calcium phosphate tribasic, aluminum hydroxide, alumina, light heavy calcium carbonate, magnesium carbonate, zirconium silicate, synthetic resin-based abrasives, and plant-derived abrasives such as coffee residue granules, and more preferably at least one selected from the group consisting of silicic acid anhydride, calcium phosphate, calcium carbonate, and zeolite. This allows the coffee oil component extract to be incorporated more stably into the oral composition.

[0021] The content of the abrasive is preferably 3 to 60 mass %, more preferably 10 to 45 mass %, and even more preferably 15 to 30 mass %. When the content of the coffee oil component extract is taken as 1, the content of the abrasive is preferably 0.3 to 6000, more preferably 2 to 900, and even more preferably 5 to 300.

[0022] <Other ingredients> The oral composition of the present invention may contain various ingredients depending on its dosage form, etc. For example, when the oral composition of the present invention is used in a toothpaste, it may contain other humectants, thickeners (binders), foaming agents, sweeteners, preservatives, flavoring ingredients, medicinal ingredients, etc.

[0023] Examples of humectants include polyhydric alcohols such as glycerin, diglycerin, polyglycerin, 1,3-butylene glycol, polyethylene glycol, 1,2-pentanediol, 1,3-hexanediol, propylene glycol, dipropylene glycol, isopropylene glycol, polypropylene glycol, ethylene glycol, polyethylene glycol, diethylene glycol, polyethylene glycol, triethylene glycol, polyethylene glycol, maltitol, reduced starch syrup, lactitol, palatinit, erythritol, sorbitol, mannitol, xylitol, xylose, trehalose, glucose, lactose, mannose, maltose, fructose, inositol, pentaerythritol, maltotriose, starch hydrolyzed sugars, and starch hydrolyzed sugar reduced alcohols. The content of the humectant is not particularly limited, but is preferably 1 to 60% by mass, and more preferably 5 to 50% by mass.

[0024] Examples of the binder (thickener) include guar gum, gelatin, agar, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, and hydrated silicic acid.

[0025] In addition to the above-mentioned nonionic surfactants, examples of the foaming agent include sodium lauryl sulfate, sodium lauroyl sarcosinate, sodium alkylsulfosuccinate, sodium coconut oil fatty acid monoglycerin sulfonate, sodium α-olefin sulfonate, N-acylamino acid salts such as N-acyl glutamate, and 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine.

[0026] Sweeteners include sodium saccharin, aspartame, trehalose, and steviosa. Examples of the sweetener include stevia extract, paramethoxycinnamic aldehyde, neohesperidyl dihydrochalcone, and perillartine, and one or more of these can be used in combination. The content of the sweetener is not particularly limited, but is preferably 0.005 to 5.0% by mass, and more preferably 0.01 to 3.0% by mass.

[0027] Examples of preservatives include parabens such as methylparaben, ethylparaben, propylparaben, and butylparaben, sodium benzoate, phenoxyethanol, and alkyldiaminoethylglycine hydrochloride, and one or more of these can be used in combination. The content of the preservative varies depending on the type, etc., but is preferably 0.005 to 5.0% by mass, and more preferably 0.01 to 3.0% by mass.

[0028] Examples of fragrance components include l-menthol, anethole, menthone, cineole, limonene, carvone, methyl salicylate, ethyl butyrate, eugenol, thymol, cinnamic aldehyde, and trans-2-hexenal. These components can be used alone or in combination with essential oils containing these. In addition to the above fragrance components, other fragrance components, such as aliphatic alcohols and their esters, terpene hydrocarbons, phenol ethers, aldehydes, ketones, and lactones, as well as essential oils, may be added within a range that does not impair the effects of the present invention. The amount of fragrance component added is not particularly limited, but is preferably 0.02 to 2% by mass, and more preferably 0.05 to 1.5% by mass.

[0029] The oral composition of the present invention may further contain active ingredients, such as tripolyphosphate, metaphosphoric acid, lysozyme chloride, tranexamic acid, sodium fluoride, potassium fluoride, sodium monofluorophosphate, polyethylene glycol, polyvinylpyrrolidone, ascorbic acid, ascorbate salts, chlorhexidine salts, cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, dequalinium chloride, isopropylmethylphenol, bisabolol, ascorbic acid and / or its derivatives, tocopherol acetate, ε-aminocaproic acid, aluminum hydroxyl allantoin, aluminum lactate, potassium nitrate, dihydrocholesterol, copper chlorophyllin salt, sodium chloride, guaiazulene sulfonate, dextranase, and pyridoxine hydrochloride, and one or more of these may be included.

[0030] In addition to the above, the oral composition of the present invention may also contain herbal extracts. Examples of herbal extracts include chamomile extract, valerian extract, jujube extract, hop extract, lavender extract, linden extract, quince extract, goldenrod extract, kumazasa extract, kelp extract, clove extract, ginseng extract, salvia extract, soapberry extract, platycodon extract, rehmannia root extract, peony extract, hawthorn extract, angelica extract, tea extract, oak salicylate extract, bark extract, white birch extract, carrot extract, aceae extract, turmeric extract, and rosemary extract, and one or more of these may be used in combination.

[0031] In addition to the above, the oral cavity composition of the present invention may also contain a pH adjuster. Examples of pH adjusters include citric acid, phosphoric acid, pantothenic acid, malic acid, pyrophosphoric acid, lactic acid, tartaric acid, glycerophosphoric acid, acetic acid, nitric acid, or chemically possible salts thereof such as disodium hydrogen phosphate, or sodium hydroxide. These may be formulated alone or in combination of two or more types so that the pH of the composition is within an appropriate range.

[0032] The oral composition of the present invention can be produced in accordance with a conventional method, and the production method is not particularly limited. The obtained oral composition can be filled into an aluminum tube, a laminated tube, a glass-deposited tube, a plastic tube, a plastic bottle, an aerosol container, or the like for use.

[0033] Although the oral composition of the present invention has been described above, the present invention is not limited thereto. For example, in addition to the components described above, the oral composition of the present invention may contain components having any desired functions. [Example]

[0034] Next, specific examples of the present invention will be described. <Production of Oral Composition> (Examples 1 to 6, Comparative Examples 1 and 2) The ingredients shown in Table 1 were prepared so as to have the contents shown in Table 1, and oral compositions (toothpastes) were produced in a conventional manner.

[0035] The coffee oil extract used was NIKKOL Cafe extract oil UC (manufactured by Nikko Chemicals Co., Ltd.).

[0036] <Stability (solubility of oil components)> The toothpastes of the Examples and Comparative Examples were stored at room temperature and at 50°C, and then the state of oil solubility in the toothpastes was visually evaluated as follows. A: It was stable for one week at 50°C. B: Separated after 1 week at 50°C, but remained stable for 24 hours at 50°C. C: Separation occurred at 50°C for 24 hours, but the mixture was stable at room temperature for 24 hours. D: Separation occurred within 24 hours at room temperature.

[0037] [Table 1]

[0038] As is clear from Table 1, the dentifrices obtained in the Examples all had excellent stability. In contrast, the dentifrices obtained in the Comparative Examples had poor stability.

Claims

1. (A) a coffee oil component extract obtained from extracted coffee powder, and (B) a nonionic surfactant. Oral composition.

2. The nonionic surfactant (B) is polyoxyethylene hydrogenated castor oil and / or glycerin fatty acid ester. The oral composition according to claim 1.

3. (C) Anionic water-soluble polymer The oral composition according to claim 1.

4. (D) Contains abrasives The oral composition according to claim 1.

5. The anionic water-soluble polymer (C) is at least one selected from the group consisting of cellulose gum, xanthan gum, carrageenan (ι, λ, κ), alginic acid, sodium alginate, potassium alginate, sodium polyacrylate, and carbomer. The oral composition according to claim 3.

6. The abrasive (D) is at least one selected from the group consisting of silicic anhydride, calcium phosphate, calcium carbonate, and zeolite. The oral composition according to claim 4.

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