Adjustment device, adjustment method, and adjustment program

Abstract

In the cultivation of microalgae, the optimal culture conditions are controlled using real-time photosynthetic activity as an indicator. [Solution] The adjusting device 100 according to this embodiment has a photosynthetic activity measuring unit 121 and a carbon dioxide supply amount adjusting unit 123. The photosynthetic activity measuring unit 121 measures the photosynthetic activity of the culture subject. If the photosynthetic activity measured by the photosynthetic activity measuring unit 121 has not reached an upper limit, the carbon dioxide supply amount adjusting unit 123 adjusts the amount of carbon dioxide supplied to the culture subject so as to increase the photosynthetic activity.

Description

[Technical Field]

[0001] The present invention relates to an adjustment device, an adjustment method, and an adjustment program. [Background technology]

[0002] In recent years, biofuel production using microalgae bioprocesses that utilize the photosynthetic ability of microalgae has been attracting attention from the perspective of utilizing atmospheric CO2 as a resource. Generally, in bioprocesses, parameters of the culture environment are measured and controlled to maintain a culture state that allows efficient culture (see, for example, Patent Document 1). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Japanese Patent Application Laid-Open No. 2010-246473 Summary of the Invention [Problem to be solved by the invention]

[0004] However, conventional techniques sometimes fail to prevent excessive CO2 supply during microalgae cultivation. For example, conventional techniques adjust the amount of CO2 supply by measuring dissolved CO2 in the culture solution. However, this method does not allow for proper adjustment of the CO2 supply, as it is not possible to determine whether the supplied CO2 is consumed by reacting with alkaline components in the culture solution or absorbed by the cells as a photosynthetic substrate. Furthermore, excessive CO2 supply is problematic because it is emitted as a greenhouse gas. [Means for solving the problem]

[0005] In order to solve the above-mentioned problems, the adjustment device of the present invention is characterized by having a photosynthetic activity measurement unit that measures the photosynthetic activity of the culture subject, and a carbon dioxide supply adjustment unit that adjusts the amount of carbon dioxide supplied to the culture subject so that the photosynthetic activity increases if the photosynthetic activity measured by the photosynthetic activity measurement unit does not reach an upper limit. [Effects of the Invention]

[0006] According to the present invention, in the cultivation of microalgae, it is possible to control the cultivation conditions to be optimal using real-time photosynthetic activity as an indicator. [Brief explanation of the drawings]

[0007] [Figure 1] FIG. 1 is a diagram showing a culture system according to an embodiment. [Figure 2] FIG. 2 is a block diagram illustrating an example of the configuration of an adjustment device according to the embodiment. [Figure 3] FIG. 3 is a diagram illustrating data stored in a storage unit according to the embodiment. [Figure 4] FIG. 4 is a diagram showing the relationship between the amount of carbon dioxide supplied and the measured value of photosynthetic activity according to the embodiment. [Figure 5] FIG. 5 is a flowchart illustrating an example of a processing procedure of the adjustment device according to the embodiment. [Figure 6] FIG. 6 is a hardware configuration diagram illustrating an example of a computer that realizes the functions of the adjustment device according to the embodiment. DETAILED DESCRIPTION OF THE INVENTION

[0008] Hereinafter, embodiments of an adjustment device, an adjustment method, and an adjustment program according to the present application will be described in detail with reference to the drawings. Note that the adjustment device, the adjustment method, and the adjustment program according to the present application are not limited to these embodiments.

[0009] [Overall structure] First, an overview of a culture system 10 according to this embodiment will be described. Fig. 1 is a diagram showing a culture system according to this embodiment. The example in Fig. 1 shows an example of a culture system 10 for cultivating microalgae, which includes an adjustment device 100, a photosynthetic activity sensor 200, a turbidity sensor 201, a control valve 210, a flow meter 211, a CO2 supply pipe 212, and a culture tank 220, and the culture tank 220 is filled with a culture solution 221. In the culture system 10, the adjustment device 100, the photosynthetic activity sensor 200, the turbidity sensor 201, and the control valve 210 are connected to each other and transmit and receive information to and from each other.

[0010] The adjusting device 100 is an information processing device that adjusts the amount of CO2 supply based on the measured value of the photosynthetic activity of the culture target, and is realized by a computer, etc. For example, when the adjusting device 100 determines that the measured value of the photosynthetic activity of the culture target notified by the photosynthetic activity sensor 200 has reached an upper limit, it adjusts the amount of CO2 supply so as not to cause an excessive supply.

[0011] The photosynthetic activity sensor 200 is, for example, a measuring device that measures the photosynthetic activity of the microalgae being cultured inline in real time. For example, the photosynthetic activity sensor 200 measures the photosynthetic activity of the microalgae by measuring the dissolved oxygen in the culture solution or the chlorophyll fluorescence of the microalgae. The turbidity sensor 201 is a measuring device that measures the turbidity of the culture solution 221.

[0012] The control valve 210 is an adjustment valve that adjusts the amount of CO2 supplied to the culture solution 221 through the CO2 supply pipe 212, and adjusts the amount of CO2 supplied in response to an adjustment instruction from the adjustment device 100 based on the measurement value of the flow meter 211. The culture tank 220 is a culture device that cultures the microalgae to be cultured, and is filled with the culture solution 221. Note that in the culture system 10, the CO2 supplied to the culture solution 221 may be supplied in a gaseous state or in a liquid state in which CO2 is dissolved, for example.

[0013] [Problems with the prior art] Next, we will explain the issues with the microalgae cultivation technology according to this embodiment. In microalgae cultivation, approximately 1 to 10% CO2 is often supplied for photosynthesis. However, when such high concentrations of CO2 are supplied, if it is not efficiently fixed, it can actually become a source of CO2. In particular, as the scale of microalgae production increases, the amount of CO2 released into the atmosphere due to excess supply increases, becoming an environmental problem that must be addressed.

[0014] Regarding the relationship between the photosynthetic activity of the culture medium and the pH of the culture solution, it has been reported that when CO2 supply is started, the photosynthetic activity increases and the pH decreases. If CO2 supply is continued, the photosynthetic activity reaches a plateau (upper limit), but the pH continues to decrease. Therefore, a technique is known in which excessive CO2 supply is determined by monitoring the pH.

[0015] However, because microalgae tend to turn their culture solution alkaline, the supplied CO2 is easily dissolved in water. Therefore, it is difficult to determine by monitoring the pH whether the supplied CO2 is dissolved in the culture solution and consumed by reacting with the alkaline components in the culture solution, or whether it is absorbed by the microalgae cells as a photosynthetic substrate. In other words, conventional monitoring of the pH of the culture solution cannot adequately determine whether the supply of CO2 to the culture medium is excessive.

[0016] [Processing Contents of Adjustment Device 100] In view of the above-mentioned problems, the adjustment device 100 according to this embodiment measures the photosynthetic activity of the culture subject, and if the measured photosynthetic activity does not reach the upper limit, adjusts the amount of carbon dioxide supplied to the culture subject so that the photosynthetic activity increases.

[0017] For example, if the rate of change in the photosynthetic activity of the microalgae measured by the photosynthetic activity sensor 200 is not stagnant at or below a predetermined value, the adjustment device 100 increases the amount of CO2 supplied and adjusts the amount of CO2 supplied so that the photosynthetic activity reaches its upper limit.

[0018] As a result, the adjustment device 100 determines the upper limit of photosynthetic activity from the measured value of the photosynthetic activity of the culture subject and adjusts the amount of CO2 supply to the amount supplied at the time the upper limit was measured, so that in the cultivation of microalgae, optimal culture conditions can be controlled using real-time photosynthetic activity as an indicator.

[0019] [Configuration of adjustment device 100] Next, the configuration of the adjustment device 100 shown in Fig. 1 will be described with reference to Fig. 2. Fig. 2 is a block diagram showing an example configuration of the adjustment device according to the embodiment. As shown in Fig. 2, the adjustment device 100 according to the embodiment includes a communication unit 110, a control unit 120, and a storage unit 130.

[0020] The communication unit 110 is realized by, for example, a network interface card (NIC), etc. The communication unit 110 is connected to the photosynthetic activity sensor 200, the turbidity sensor 201, the control valve 210, and the flow meter 211 by wire or wirelessly, and transmits and receives information.

[0021] The storage unit 130 is realized by a storage device such as a RAM (Random Access Memory) or a hard disk. The storage unit 130 stores data and programs necessary for various processes by the control unit 120. The storage unit 130 stores various culture parameters measured by the photosynthetic activity sensor 200, the turbidity sensor 201, and the flow meter 211 for each measurement time.

[0022] Here, the measurement data stored in the storage unit 130 will be described with reference to Fig. 3. Fig. 3 is a diagram illustrating data stored in the storage unit according to the embodiment. As shown in Fig. 3, the storage unit 130 stores measurement data relating to items such as "measurement time," "photosynthetic activity," "CO2 supply amount," "medium component amount," and "turbidity," for example.

[0023] "Measurement time" stores, for example, measurement time in one-minute cycles. "Photosynthetic activity" stores the measured value of the photosynthetic activity of the culture target measured by the photosynthetic activity sensor 200 at the measurement time. "CO2 supply amount" stores the flow rate of CO2 supplied through the CO2 supply pipe 212 measured by the flow meter 211 at the measurement time. "Culture medium component amount" stores the component amount and ratio of each component that makes up the culture medium at the measurement time. "Turbidity" stores the turbidity of the culture solution 221 measured by the turbidity sensor 201 at the measurement time.

[0024] Returning to the explanation of Fig. 2, the control unit 120 is realized by a CPU (Central Processing Unit), an MPU (Micro Processing Unit), or the like executing various programs stored in a storage device inside the adjusting device 100 using RAM as a work area. The control unit 120 is also realized by an integrated circuit such as an ASIC (Application Specific Integrated Circuit) or an FPGA (Field Programmable Gate Array). The control unit 120 has a photosynthetic activity measurement unit 121, a photosynthetic activity determination unit 122, a carbon dioxide supply amount adjustment unit 123, a medium component amount adjustment unit 124, and a production amount determination unit 125.

[0025] The photosynthetic activity measurement unit 121 measures the photosynthetic activity of the culture target. For example, the photosynthetic activity measurement unit 121 acquires measurement values ​​of dissolved oxygen in the culture solution and chlorophyll fluorescence of the microalgae measured by a photosynthetic activity sensor 200, which is a measurement device that measures the photosynthetic activity of the microalgae to be cultured inline in real time. The photosynthetic activity measurement unit 121 then stores the acquired measurement values ​​in the memory unit 130.

[0026] The photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit when the rate of change in the photosynthetic activity measured by the photosynthetic activity measurement unit 121 over a predetermined period is equal to or less than a predetermined threshold. For example, the photosynthetic activity determination unit 122 calculates the rate of change per minute for the measured value of the photosynthetic activity measured by the photosynthetic activity measurement unit 121 described above, and determines that the photosynthetic activity of the culture subject has reached its upper limit when it is determined that the rate of change is equal to or less than a preset threshold.

[0027] Here, the threshold value for determining the photosynthetic activity described above is a value that can appropriately determine whether the photosynthetic activity has reached its upper limit. Note that the processing of the photosynthetic activity determination unit 122 is not limited to the processing using the rate of change described above, and for example, by using the upper limit value of the photosynthetic activity predicted for each amount of microalgae to be cultured as a threshold value and comparing it with the measured value of the photosynthetic activity, it can be determined whether the photosynthetic activity of the culture target has reached its upper limit.

[0028] The carbon dioxide supply amount adjusting unit 123 adjusts the amount of carbon dioxide supplied to the culture subject so as to increase the photosynthetic activity when the photosynthetic activity measured by the photosynthetic activity measuring unit 121 has not reached its upper limit. For example, when the photosynthetic activity determining unit 122 has not determined that the photosynthetic activity has reached its upper limit, the carbon dioxide supply amount adjusting unit 123 adjusts the amount of CO2 supply by gradually increasing the amount of CO2 supply until the photosynthetic activity reaches its upper limit.

[0029] Furthermore, when the photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit, the carbon dioxide supply amount adjustment unit 123 adjusts the amount of carbon dioxide to be supplied to the culture subject to the average value of the amount of carbon dioxide supplied at the time when it was determined that the rate of change was equal to or less than the threshold. For example, when the carbon dioxide supply amount adjustment unit 123 is notified that the photosynthetic activity determination unit 122 has determined that the photosynthetic activity has reached its upper limit, it adjusts the amount of CO2 supply to the average value of the measured values ​​in the range in which the rate of change was calculated, thereby adjusting the amount of CO2 to be supplied to the culture subject to be an optimal amount.

[0030] If the photosynthetic activity measured by the photosynthetic activity measurement unit 121 has not reached its upper limit, the medium component amount adjustment unit 124 adjusts the amount of the medium component supplied to the culture subject so as to increase the photosynthetic activity. For example, if the photosynthetic activity determined by the photosynthetic activity determination unit 122 is equal to or lower than a predetermined threshold, the medium component amount adjustment unit 124 can add medium components such as iron and magnesium to the culture medium to increase the photosynthetic activity.

[0031] Furthermore, when the photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit, the medium component amount adjustment unit 124 adjusts the amount of the medium component to be supplied to the culture subject to the average amount of the medium component supplied over a predetermined period. For example, when the photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit, the medium component amount adjustment unit 124 adjusts the amount of the medium component to be supplied to the culture subject to the average amount of the medium component supplied at the time when it was determined that the rate of change was equal to or less than the threshold.

[0032] The production amount determination unit 125 determines the production amount of the culture target based on the measurement result of the turbidity of the culture solution 221. For example, the production amount determination unit 125 acquires a turbidity measurement value measured by the turbidity sensor 201 for the culture solution 221 producing the culture target microalgae. Then, the production amount determination unit 125 compares the turbidity measurement value with a threshold value set in advance according to the target production amount, and determines whether the culture target microalgae have reached the target production amount.

[0033] In addition, the production amount determination unit 125 can determine the production amount of the culture target based on, for example, the dry cell weight of the culture target or the measurement results of the product amount of the culture target, in addition to the turbidity of the culture solution 221 described above.

[0034] [Specific example] Here, the flow of the CO2 supply amount adjustment process performed by the adjusting device 100 will be described with reference to Fig. 4. Fig. 4 is a diagram showing the relationship between the carbon dioxide supply amount and the measured value of photosynthetic activity according to an embodiment. Specifically, Fig. 4 shows a graph representing changes in photosynthetic activity (solid line) and CO2 supply amount (dotted line) with the measured values ​​of photosynthetic activity (QY) and CO2 supply amount on the vertical axis and time on the horizontal axis.

[0035] First, at the start of cultivation, the carbon dioxide supply amount adjusting unit 123 adjusts the amount of CO2 supplied so as to supply a constant amount of CO2. Here, the photosynthetic activity determining unit 122 determines that the photosynthetic activity has not reached its upper limit because the rate of change is not equal to or less than a predetermined value due to a tendency for the photosynthetic activity to decrease.

[0036] Then, since it is determined that the photosynthetic activity has not reached the upper limit, the carbon dioxide supply amount adjustment unit 123 gradually increases the CO2 supply amount. As a result, the photosynthetic activity tends to increase, but because the rate of change is greater than the predetermined value, the photosynthetic activity determination unit 122 determines that the photosynthetic activity has not reached the upper limit, as was the case at the start of cultivation.

[0037] The carbon dioxide supply amount adjusting unit 123 then increases the CO2 supply amount, but the photosynthetic activity determining unit 122 determines that the rate of change during the period (1) is equal to or less than a predetermined value and determines that the photosynthetic activity of the culture target has reached its upper limit. As a result, the carbon dioxide supply amount adjusting unit 123 calculates the average value of the CO2 supply amount during the period (1) and reduces the CO2 supply amount so that it becomes the calculated average value.

[0038] Through the above-described series of processes, the adjustment device 100 can adjust the CO2 supply amount so as to maintain the CO2 supply amount at the time when the upper limit value of the photosynthetic activity of the culture subject is measured, thereby preventing excessive CO2 supply in the cultivation of microalgae.

[0039] [Processing Procedure by Adjustment Device 100] Next, an example of a processing procedure by the adjustment device 100 according to the embodiment will be described with reference to Fig. 5. Fig. 5 is a flowchart showing an example of a processing procedure by the adjustment device according to the embodiment. Note that the steps in the flowchart shown in Fig. 5 may be executed in a different order, and some processing may be omitted.

[0040] First, the adjustment device 100 acquires measurement results of various culture parameters (S101). Then, the adjustment device 100 measures the photosynthetic activity of the culture target (S102). Then, if the adjustment device 100 determines that the photosynthetic activity is lower than the predicted value (S103; Yes), it increases the amount of CO2 supply (S104).

[0041] If the adjustment device 100 determines that the rate of change in photosynthetic activity is not the predetermined value (S105; No), the adjustment device 100 returns to S104 and continues the process. On the other hand, if the adjustment device 100 determines that the rate of change in photosynthetic activity is equal to or less than the predetermined value (S105; Yes), the adjustment device 100 adjusts the supply amount so that the CO2 supply amount does not become excessive (S106).

[0042] Then, if the adjustment device 100 has not determined that the photosynthetic activity is lower than the predicted value (S103; No), or if it has determined that the culture target has reached the planned production volume after the processing of S106 (S107; Yes), it ends the process. On the other hand, if the adjustment device 100 has not determined that the culture target has reached the planned production volume (S107; No), it returns to S101 and continues the processing.

[0043] [Effects of the embodiment] As described above, the adjusting device 100 according to this embodiment has a photosynthetic activity measuring unit 121 and a carbon dioxide supply amount adjusting unit 123. The photosynthetic activity measuring unit 121 measures the photosynthetic activity of the culture subject. If the photosynthetic activity measured by the photosynthetic activity measuring unit 121 has not reached an upper limit, the carbon dioxide supply amount adjusting unit 123 adjusts the amount of carbon dioxide supplied to the culture subject so as to increase the photosynthetic activity.

[0044] As a result, when the photosynthetic activity of the culture subject has not reached its upper limit, the adjustment device 100 can increase the CO2 supply amount and adjust the CO2 supply amount to an optimal amount. Therefore, in the culture of microalgae, the optimal culture conditions can be controlled using real-time photosynthetic activity as an indicator.

[0045] The adjusting device 100 further includes a photosynthetic activity determining unit 122. The photosynthetic activity determining unit 122 determines that the photosynthetic activity has reached its upper limit when the rate of change in the photosynthetic activity measured by the photosynthetic activity measuring unit 121 over a predetermined period is equal to or less than a predetermined threshold. As a result, the adjusting device 100 can appropriately determine the stagnant state (upper limit of photosynthetic activity) of the culture target from the rate of change in the photosynthetic activity.

[0046] Furthermore, when the photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit, the carbon dioxide supply amount adjustment unit 123 adjusts the amount of carbon dioxide supplied to the culture subject to the average amount of carbon dioxide supplied over a predetermined period of time. As a result, the adjustment device 100 can adjust the amount of CO2 supply to the optimal amount at the time when the photosynthetic activity of the culture subject has reached its upper limit.

[0047] The adjusting device 100 also has a medium component amount adjusting unit 124. When the photosynthetic activity measured by the photosynthetic activity measuring unit 121 has not reached its upper limit, the medium component amount adjusting unit 124 adjusts the amount of medium component supplied to the culture subject so as to increase the photosynthetic activity. As a result, when the photosynthetic activity has not reached its upper limit and the medium component conditions are not optimal, the adjusting device 100 can add components such as iron and magnesium to the medium to control the culture conditions to optimal.

[0048] Furthermore, when the photosynthetic activity determination unit 122 determines that the photosynthetic activity has reached its upper limit, the medium component amount adjustment unit 124 adjusts the amount of the medium component to be supplied to the culture subject to the average amount of the medium component supplied over a predetermined period of time. As a result, the adjustment device 100 can adjust the amount of the medium component to be supplied so that the amount is optimal when the photosynthetic activity of the culture subject has reached its upper limit.

[0049] The adjusting device 100 further includes a production amount determination unit 125. The production amount determination unit 125 determines the production amount of the culture target based on the measurement results of the turbidity of the culture solution in which the culture target is cultured. As a result, the adjusting device 100 can easily determine whether the production amount of the culture target has reached a planned amount.

[0050] Furthermore, the production amount determination unit 125 makes a determination based on the measurement results of one or more of the turbidity of the culture solution, the dry cell weight, and the amount of product. As a result, the adjusting device 100 can appropriately determine the production amount of the culture target using a measurement method other than turbidity.

[0051] [Hardware configuration] The adjustment device 100 according to the embodiment described above is realized, for example, by a computer 1000 configured as shown in Fig. 6. Fig. 6 is a hardware configuration diagram showing an example of a computer that realizes the functions of the adjustment device according to the embodiment. The computer 1000 has a configuration in which a CPU 1100, a RAM 1200, a ROM 1300, an auxiliary storage device 1400, a communication I / F (interface) 1500, and an input / output I / F (interface) 1600 are connected by a bus 1800.

[0052] The CPU 1100 operates and controls each unit based on programs stored in the ROM 1300 or the auxiliary storage device 1400. The ROM 1300 stores a boot program executed by the CPU 1100 when the computer 1000 starts up, programs that depend on the hardware of the computer 1000, and the like.

[0053] The auxiliary storage device 1400 stores programs executed by the CPU 1100, data used by the programs, etc. The communication I / F 1500 receives data from other devices via a predetermined communication network and sends it to the CPU 1100, and transmits data generated by the CPU 1100 to other devices via the predetermined communication network.

[0054] The CPU 1100 controls output devices such as a display and a printer, and input / output devices 1700 such as a keyboard and a mouse, via the input / output I / F 1600. The CPU 1100 acquires data from the input / output device 1700 via the input / output I / F 1600. The CPU 1100 also outputs generated data to the input / output device 1700 via the input / output I / F 1600.

[0055] For example, when the computer 1000 functions as the adjustment device 100 according to this embodiment, the CPU 1100 of the computer 1000 executes a program loaded onto the RAM 1200 to realize the functions of the control unit 120 .

[0056] 〔others〕 Of the processes described in the above embodiments, all or part of the processes described as being performed automatically can be performed manually, or all or part of the processes described as being performed manually can be performed automatically using known methods. In addition, the information including the processing procedures, specific names, various data, and parameters shown in the above documents and drawings can be changed as desired unless otherwise specified. For example, the various information shown in each drawing is not limited to the information shown in the drawings.

[0057] Furthermore, the components of each device shown in the figure are conceptual functional components and do not necessarily have to be physically configured as shown in the figure. In other words, the specific form of distribution and integration of each device is not limited to that shown in the figure, and all or part of them can be functionally or physically distributed and integrated in any unit depending on various loads, usage conditions, etc.

[0058] The above-described components include those that can be easily imagined by a person skilled in the art, those that are substantially the same, and those that are within the scope of what is called equivalents. Furthermore, the above-described embodiments can be appropriately combined within the scope that does not cause contradictions in the processing content.

[0059] Furthermore, the aforementioned "section, module, unit" can be read as "means" or "circuit," etc. For example, a control section can be read as control means or a control circuit.

[0060] Although some embodiments of the present invention have been described in detail above with reference to the drawings, these are merely examples, and the present invention can be implemented in other forms that include the embodiments described in the Disclosure of the Invention section, as well as in various other forms that have been modified and improved based on the knowledge of those skilled in the art. [Explanation of symbols]

[0061] 10. Culture System 100 Adjustment device 110 Communications Department 120 control section 121 Photosynthetic Activity Measurement Unit 122 Photosynthetic activity determination section 123 Carbon Dioxide Supply Adjustment Unit 124 Medium component amount adjustment unit 125 Production volume determination unit 130 Storage section 200 Photosynthetic Activity Sensor 201 Turbidity sensor 210 Control Valve 211 Flow meter 212 CO2 supply pipe 220 Culture tank 221 Culture solution

Claims

1. a photosynthetic activity measurement unit that measures the photosynthetic activity of the culture target; a carbon dioxide supply amount adjusting unit that adjusts the amount of carbon dioxide supplied to the culture subject so that the photosynthetic activity increases when the photosynthetic activity measured by the photosynthetic activity measuring unit has not reached an upper limit; An adjustment device comprising:

2. The adjusting device described in claim 1, further comprising a photosynthetic activity determination unit that determines that the photosynthetic activity has reached an upper limit when the rate of change of the photosynthetic activity measured by the photosynthetic activity measurement unit over a predetermined period is below a predetermined threshold.

3. 3. The adjusting device according to claim 2, wherein the carbon dioxide supply amount adjusting unit adjusts the amount of carbon dioxide supplied to the culture target to an average value of the amount of carbon dioxide supplied during the predetermined period when the photosynthetic activity determining unit determines that the photosynthetic activity has reached an upper limit.

4. a photosynthetic activity measurement unit that measures the photosynthetic activity of the culture target; a medium component amount adjusting unit that adjusts the amount of the medium component supplied to the culture object so that the photosynthetic activity increases when the photosynthetic activity measured by the photosynthetic activity measuring unit has not reached an upper limit; and An adjustment device comprising:

5. The adjusting device described in claim 4, further comprising a photosynthetic activity determination unit that determines that the photosynthetic activity has reached an upper limit when the rate of change of the photosynthetic activity measured by the photosynthetic activity measurement unit over a predetermined period is below a predetermined threshold.

6. 6. The adjusting device according to claim 5, wherein the medium component amount adjusting unit adjusts the amount of the medium component to be supplied to the culture object to an average amount of the medium component supplied during the predetermined period when the photosynthetic activity determining unit determines that the photosynthetic activity has reached an upper limit.

7. a photosynthetic activity measurement unit that measures the photosynthetic activity of the culture target; a carbon dioxide supply amount adjusting unit that adjusts the amount of carbon dioxide supplied to the culture subject to a predetermined value when the photosynthetic activity measured by the photosynthetic activity measuring unit reaches an upper limit; a medium component amount adjusting unit that adjusts the amount of the medium component supplied to the culture object so that the photosynthetic activity increases when the photosynthetic activity measured by the photosynthetic activity measuring unit has not reached an upper limit; and An adjustment device comprising:

8. 5. The adjusting device according to claim 1, further comprising a production amount determining unit that determines the production amount of the culture target based on a measurement result of the turbidity of the culture solution in which the culture target is cultured.

9. 9. The adjusting device according to claim 8, wherein the production amount determining unit makes a determination based on the results of measurement of one or more of the turbidity of the culture solution, the dry cell weight, and the amount of product.

10. A regulation method performed by a regulation device, comprising: a photosynthetic activity measurement step of measuring the photosynthetic activity of the culture target; a carbon dioxide supply amount adjusting step of adjusting the amount of carbon dioxide supplied to the culture subject to a predetermined value when the photosynthetic activity measured by the photosynthetic activity measuring step reaches an upper limit; An adjustment method comprising:

11. a photosynthetic activity measurement procedure for measuring the photosynthetic activity of the cultured object; a carbon dioxide supply amount adjusting step of adjusting the amount of carbon dioxide supplied to the culture subject to a predetermined value when the photosynthetic activity measured by the photosynthetic activity measuring step reaches an upper limit; An adjustment program that causes a computer to execute the above.

12. A regulation method performed by a regulation device, comprising: a photosynthetic activity measurement step of measuring the photosynthetic activity of the culture target; a medium component amount adjusting step of adjusting the amount of the medium component supplied to the culture subject so as to increase the photosynthetic activity when the photosynthetic activity measured by the photosynthetic activity measuring step has not reached an upper limit; An adjustment method comprising:

13. a photosynthetic activity measurement procedure for measuring the photosynthetic activity of the cultured object; a medium component amount adjusting step of adjusting the amount of the medium component supplied to the culture subject so as to increase the photosynthetic activity when the photosynthetic activity measured by the photosynthetic activity measuring step has not reached an upper limit; An adjustment program that causes a computer to execute the above.

14. A regulation method performed by a regulation device, comprising: a photosynthetic activity measurement step of measuring the photosynthetic activity of the culture target; a carbon dioxide supply amount adjusting step of adjusting the amount of carbon dioxide supplied to the culture subject to a predetermined value when the photosynthetic activity measured by the photosynthetic activity measuring step reaches an upper limit; a medium component amount adjusting step of adjusting the amount of the medium component supplied to the culture subject so as to increase the photosynthetic activity when the photosynthetic activity measured by the photosynthetic activity measuring step has not reached an upper limit; An adjustment method comprising:

15. a photosynthetic activity measurement procedure for measuring the photosynthetic activity of the cultured object; a carbon dioxide supply amount adjusting step of adjusting the amount of carbon dioxide supplied to the culture subject to a predetermined value when the photosynthetic activity measured by the photosynthetic activity measuring step reaches an upper limit; a medium component amount adjusting step of adjusting the amount of the medium component supplied to the culture subject so as to increase the photosynthetic activity when the photosynthetic activity measured by the photosynthetic activity measuring step has not reached an upper limit; An adjustment program that causes a computer to execute the above.

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