Automated analysis method and automated analysis system for polymer end groups

Abstract

This invention relates to an automated method and system for the analysis of polymer end groups. Since the analysis process following the weighing of the polymer sample is performed automatically, this invention provides the tester with an improved analytical work environment and enables the acquisition of reliable analytical results.

Description

Detailed Description of the Invention

[0001] [Technical Field] The present invention relates to a method and an automatic analysis system for automatically analyzing end groups of a polymer to predict the molecular weight and properties (physical properties) of the polymer by analyzing the end groups of the polymer through an automated process.

[0002] [Background Art] Analysis of end groups bonded to a polymer is used as one of the methods for predicting the molecular weight of the polymer and identifying basic properties that affect the physical properties after processing the polymer.

[0003] The method for analyzing the end groups of a polymer includes the step of titrating a polymer sample. Specifically, the polymer sample is weighed, then dissolved and cooled, an indicator and a titrant are added, and a color change is visually observed to analyze the content of the end groups of the polymer.

[0004] However, the method of titrating a polymer sample has limitations in that the entire procedure is performed manually, so it is labor-intensive. There is also a problem that errors occur in the analysis results due to differences in judgment criteria among testers. In addition, the tester is exposed to high temperatures to dissolve the solvent and polymer sample used in each procedure, so the safety of the tester during the test may be impaired. In addition, there is also the inconvenience that all test tubes, beakers, and other instruments used in the titration procedure must be washed in order to be reused.

[0005] Therefore, in the analysis of polymer end groups, it is necessary to develop an analysis technique that can improve the working environment of testers while reducing errors in analysis results.

[0006] [Prior Art Documents] [Patent Document 1] Korean Patent Application Publication No. 2020-0046622

[0007] [Disclosure of the Invention] [Technical Problem] The object of the present invention is to provide an automated method and system for analyzing polymer end groups that minimize errors in analytical results and improve the working environment for testers by analyzing polymer end groups through an automated process.

[0008] [Solutions to the problem] To achieve the above objective, the present invention provides an automated method for analyzing polymer end groups, comprising the steps of: (1) attaching a container containing a polymer sample to an autosampler; (2) adding a solvent containing an aromatic compound having at least one hydroxyl group to the container containing the polymer sample and heating it to obtain a polymer sample solution; (3) cooling the polymer sample solution; (4) adding an indicator to the cooled polymer sample solution and titrating it with a titrator to observe the change in the potential value of a colorimetric electrode; and (5) analyzing the change in potential value with software to calculate the content of polymer end groups.

[0009] In addition, the present invention includes a sample supply unit equipped with an autosampler to which a container containing a polymer sample is attached; a heating unit equipped with a solvent injection tube for injecting a solvent containing an aromatic compound having at least one hydroxyl group into the container containing the polymer sample; a heating rod for heating the polymer sample to which the solvent has been injected; and a cooling solvent injection tube for injecting a cooling solvent for cooling the polymer sample solution obtained by heating; an indicator injection tube for injecting an indicator into the polymer sample solution cooled by the cooling solvent; a titrator injection tube for injecting a titrator into the polymer sample solution to which the indicator has been injected; and a heating unit equipped with an indicator injection tube for injecting a titrator into the polymer sample solution to which the indicator has been injected, depending on the amount of titrator injected The present invention provides an automated analysis system for polymer end groups comprising: a titration unit equipped with a colorimetric electrode that shows changes in potential value; a dispensing control unit equipped with a solvent dispenser for injecting solvent into a solvent injection tube, an indicator dispenser for dispensing indicator into an indicator injection tube, and a titrant dispenser for dispensing titrant into a titrant injection tube; a pump control unit equipped with a solvent supply pump for supplying solvent to the solvent dispenser and a cooling solvent supply pump for supplying cooling solvent to a cooling solvent injection tube; and an automated data processing unit equipped with software for analyzing changes in potential value and an output device for outputting the analysis results obtained by the software.

[0010] [Advantageous effects of the invention] According to the present invention, since the analysis procedure for polymer end groups is controlled by software, highly accurate analysis results can be obtained. In addition, since the analysis procedure for end groups after weighing the polymer sample is performed entirely automatically, the working environment for the tester (analyst) can be improved (safety is ensured and labor is saved). [Brief explanation of the drawing]

[0011] [Figure 1] This flowchart shows the automated analysis procedure for polymer end groups according to an embodiment of the present invention. [Figure 2] This is a schematic diagram showing an automated analysis system for polymer end groups according to an embodiment of the present invention.

[0012] [Best method for making an invention] The present invention will now be described in detail. The invention described herein is not limited to the disclosures shown below and may be modified in various forms without altering the essence of the invention.

[0013] In this specification, the term “comprising” is intended to identify specific characteristics, areas, steps, processes, elements, and / or components. Unless otherwise stated, it does not preclude the presence or addition of any other characteristics, areas, steps, processes, elements, and / or components.

[0014] All numerical values ​​and expressions relating to the amounts of components and reaction conditions used herein should be understood to be modified by the term "approximately" unless otherwise indicated.

[0015] For illustrative purposes, the sizes of individual elements in the attached drawings may be exaggerated and may not reflect their actual sizes.

[0016] Automated analysis method for polymer end groups This invention relates to a method for analyzing the end groups of a polymer to predict its molecular weight and to identify fundamental properties that affect the polymer's physical properties after processing. A key feature is that all steps after weighing the polymer sample are performed automatically.

[0017] More specifically, the automated analysis method for polymer end groups according to the present invention includes the steps of: (1) attaching a container containing a polymer sample to an autosampler; (2) adding a solvent containing an aromatic compound having at least one hydroxyl group to the container containing the polymer sample and heating it to obtain a polymer sample solution; (3) cooling the polymer sample solution; (4) adding an indicator to the cooled polymer sample solution and titrating it with a titrator to observe the change in the potential value of a colorimetric electrode; and (5) analyzing the change in potential value with software to calculate the polymer end group content. This will be explained below with reference to Figure 1.

[0018] Step (1): Attach the container to the autosampler. According to the present invention, step (1) is to attach containers containing polymer samples to an autosampler. The number of containers attached to the autosampler may be one or more. In particular, it may be 1 to 25, 2 to 20, or 5 to 15.

[0019] On the other hand, the polymer sample may be weighed to a predetermined amount before being placed in the container.

[0020] Step (2): Obtain a polymer sample solution. According to the present invention, step (2) is to add a solvent containing an aromatic compound having at least one hydroxyl group to a container containing a polymer sample and heat it to obtain a polymer sample solution.

[0021] The aromatic compound in the solvent has at least one hydroxyl group (more specifically, 1 to 4 hydroxyl groups or 1 to 2 hydroxyl groups) and is not particularly limited as long as it does not react with the polymer sample and does not have a carboxyl group. More specifically, the aromatic compound having at least one hydroxyl group may include at least one selected from the group consisting of phenol, o-cresol, m-cresol, p-cresol, o-chlorophenol, m-chlorophenol, p-chlorophenol, 2,6-xylenol, catechol, resorcinol, hydroquinone, pyrogallol, and benzyl alcohol. When the solvent contains an aromatic compound, the polymer sample can be dissolved at a relatively low heating temperature, thereby stabilizing the heating procedure (e.g., the procedure of heating a mixture of the polymer sample and solvent with a heating rod). As a result, the analytical procedure can be automated.

[0022] The heating of the polymer sample into which the solvent has been injected can be carried out in detail at 60 to 100°C for 400 to 900 seconds. More specifically, the heating can be carried out at 60 to 90°C, 60 to 85°C, 63 to 80°C, 65 to 75°C, 65 to 70°C, or 65 to 68°C for 400 to 800 seconds, 430 to 700 seconds, 450 to 650 seconds, 500 to 650 seconds, 500 to 600 seconds, or 500 to 550 seconds. When the heating temperature and heating time are within the above ranges, the polymer sample can be well dissolved without the solvent boiling, and a polymer sample solution can be efficiently obtained.

[0023] On the other hand, a solvent containing an aromatic compound having at least one hydroxy group has a low freezing point, and thus, when the temperature of the analysis environment becomes lower than a specific level, it may freeze and adhere to the container. Therefore, the solvent can further contain at least one auxiliary solvent selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol. When the solvent further contains an auxiliary solvent, the freezing point of the solvent can be increased to prevent the solvent from freezing (prevent precipitation of the solvent). As a result, the automation of the analysis procedure can be satisfactorily carried out.

[0024] When the solvent contains an aromatic compound (a) having at least one hydroxy group and an auxiliary solvent (b), their mixing ratio (a:b) is not particularly limited. Specifically, it may be a weight ratio of 5:1 to 1:5, 4:1 to 1:4, 3:1 to 1:3, or 2:1 to 1:2. When the mixing ratio is within the above range, the solvent does not freeze, and the polymer sample having the solvent can be well dissolved within the range of the heating temperature and heating time, and thus, a polymer sample solution can be efficiently obtained.

[0025] Step (3): Cool the polymer sample solution. According to the present invention, step (3) is to cool the polymer sample solution. The cooling of the polymer sample solution can be carried out naturally or intentionally. Specifically, natural cooling can be carried out by leaving the polymer sample solution at room temperature for a specific time. Intentional cooling can be carried out by injecting a cooling solvent into the polymer sample solution.

[0026] The cooling solvent may include at least one selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol. When the polymer sample solution is cooled by the cooling solvent, the polymer sample solution can be cooled in a short time. In addition, in the procedure of injecting the cooling solvent into the polymer sample solution, the heating rod used to heat the mixture of polymer sample and solvent can be automatically cleaned. As a result, manual cleaning procedures for managing the heating rod as a heat source are eliminated, and thus the present invention can provide the tester with an improved working environment.

[0027] Step (4): Titration of polymer sample solution According to the present invention, step (4) involves adding an indicator to a cooled polymer sample solution, titrating it with a titrant, and observing the change in the potential value of the colorimetric electrode. Conditions such as the amount, rate, and time of addition of the indicator and titrant to the polymer sample solution can be automatically controlled by values ​​pre-set (input) in the software. In addition, the change in the potential value of the colorimetric electrode can also be confirmed by the output of the results collected by the software.

[0028] The indicator may, in particular, include at least one selected from the group consisting of bromophenol blue, phenol red, and methyl red. When the indicator contains the above components, the sensitivity (reactivity) of the colorimetric electrode is increased, thereby enabling the acquisition of highly accurate analytical results.

[0029] The titrant may, in particular, contain at least one selected from the group consisting of sodium hydroxide (NaOH) and potassium hydroxide (KOH). The inclusion of the above components in the titrant can improve the titration efficiency.

[0030] Step (5): Calculation of polymer end group content According to the present invention, step (5) is to analyze the change in potential value with software and calculate the polymer end group content. Specifically, the software automatically calculates the polymer end group content by analyzing the change in potential value as an inflection point (equivalent point change) in the collected data.

[0031] This software may be integrated with, or separate from, the software that controls the conditions for adding the indicator and titrant in step (4).

[0032] On the other hand, the automated analysis method for polymer end groups according to the present invention may further include a step (step (6)) of washing the colorimetric electrode of step (4) by supplying a washing solvent. The washing solvent may, in particular, be at least one selected from the group consisting of acetone, acetonitrile, isopropanol, and water. When the washing solvent contains the above components, the colorimetric electrode can be efficiently washed. As a result, manual washing procedures for managing the colorimetric electrode are not required, and therefore the present invention can provide an improved working environment for the tester.

[0033] The polymer (polymer sample) that can be analyzed by the automated analysis method according to the present invention is not particularly limited as long as it is a polymer having a carboxyl group. More specifically, it may be polyethylene terephthalate (PET) or polyethylene terephthalate glycol (PETG).

[0034] In addition, the terminal groups of the polymer to be analyzed by the automated analysis method according to the present invention are not particularly limited. They may be carboxyl groups (COOH), whose content can be confirmed relatively accurately by this automated analysis method.

[0035] As described above, the automated analysis method according to the present invention automatically performs procedures such as dissolution, cooling, titration, and washing after weighing the polymer sample, thereby significantly reducing the amount of labor required for the analysis procedure while ensuring the stability of the analyst's work. In addition, since the analysis procedure for polymer end groups is controlled by software in the automated analysis method according to the present invention, highly accurate analysis results can be obtained.

[0036] Automated analysis system for polymer end groups The present invention provides an automated analysis system for polymer end groups that can carry out the automated analysis method described above. More specifically, the automated analysis system for polymer end groups according to the present invention comprises a sample supply unit, a heating unit, a titration unit, a dispensing control unit, a pump control unit, and an automated data processing unit. This will be described below with reference to Figure 2.

[0037] Sample supply unit According to the present invention, the sample supply unit (10) comprises an autosampler (11) to which a container (12) containing a polymer sample is attached.

[0038] The autosampler (11) sequentially supplies containers (12) containing polymer samples to the heating unit (20) and the titration unit (30). At least one container (12), more specifically, 1 to 25, 2 to 20, or 5 to 15 containers may be attached. In this invention, an autosampler (11) capable of attaching multiple containers (12) is used, and the attached containers (12) are automatically supplied to the heating unit (20) and the titration unit (30) for heating and titration, respectively, so that multiple polymer samples can be analyzed at once and highly accurate analytical results can be obtained.

[0039] On the other hand, the container (12) attached to the autosampler (11) may be a disposable container or a multi-purpose container. More specifically, it may be a disposable container made of polypropylene (PP). If the container (12) is a disposable container, the conventional task of washing the used container at the end of the analysis can be omitted. Here, since the heating in the heating unit (20) is performed at a relatively low temperature (e.g., 60-90°C), disposable containers may be used.

[0040] Heating unit According to the present invention, the heating unit (20) comprises a solvent injection tube (21) for injecting a solvent containing an aromatic compound having at least one hydroxyl group into a container (12) containing a polymer sample, a heating rod (22) for heating the polymer sample into which the solvent has been injected, and a cooling solvent injection tube (23) for injecting a cooling solvent to cool the polymer sample solution obtained by heating.

[0041] The solvent injection tube (21) and the cooling solvent injection tube (23) are not particularly limited as long as they have a structure that allows the solvent and cooling solvent to flow smoothly and are made of a material that is durable against each solvent. In addition, the heating rod (22) is not particularly limited as long as it can stably dissolve the polymer sample into which the solvent has been injected.

[0042] Here, in order to ensure stable operation of the heating rod (22), the solvent injected through the solvent injection tube (21) may further include at least one auxiliary solvent selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol. That is, a mixed solvent, which is a mixture of an aromatic compound having at least one hydroxyl group and the auxiliary solvent, can be injected into the container (12) through the solvent injection tube (21).

[0043] In addition, the heating rod (22) can be cleaned by the cooling solvent injected through the cooling solvent injection tube (23) as the polymer sample solution is cooled. In such a case, the cleaning procedure of the heating rod (22) using the cooling solvent may be performed simultaneously with the cooling procedure of the polymer sample solution, or before or after the cooling procedure of the polymer sample solution.

[0044] The heating unit (20) may further include a stirrer (not shown) for promoting the dissolution of the polymer sample and a discharge device (not shown) for automatically discharging the cooling solvent used in the cleaning procedure of the heating rod (22).

[0045] Titration unit The titration unit (30) includes an indicator injection tube (31) for injecting an indicator into a polymer sample solution cooled by a cooling solvent, a titrant injection tube (32) for injecting a titrant into the polymer sample solution containing the indicator, and a colorimetric electrode (33) that shows a change in potential value according to the amount of titrant injected.

[0046] The indicator injection tube (31) and the titrant injection tube (32) are not particularly limited as long as they have a structure that allows the indicator and titrant to flow smoothly and are made of materials that are durable against the indicator and titrant, respectively.

[0047] In addition, the colorimetric electrode (33) is not particularly limited as long as it clearly shows a change in potential value (change in color) corresponding to the amount of titrant injected. More specifically, the colorimetric electrode (33) may be a photometric sensor electrode (optrode). When a photometric sensor electrode is used, titration analysis can be performed quickly, simply, and accurately.

[0048] On the other hand, the titration unit (30) may further include a washing solvent injection tube (34) for injecting a washing solvent to wash the colorimetric electrode (33). The washing solvent injection tube (34) is not particularly limited as long as it has a structure that allows the washing solvent to flow smoothly and is made of a material that is resistant to the washing solvent.

[0049] In addition, the titration unit (30) may further include a stirrer (not shown) for facilitating the titration of the polymer sample solution and a discharge device (not shown) for automatically discharging the washing solvent used in the cleaning procedure of the colorimetric electrode (33).

[0050] Dispensing control unit According to the present invention, the dispensing control unit (40) comprises a solvent dispenser (41) for dispensing a solvent into a solvent injection tube (21), an indicator dispenser (42) for dispensing an indicator into an indicator injection tube (31), and a titrant dispenser (43) for dispensing a titrant into a titrant injection tube (32).

[0051] The solvent dispenser (41), indicator dispenser (42), and titrator dispenser (43) are not particularly limited, as long as they have a structure that allows the solvent, indicator, and titrator to flow smoothly, and are made of materials that are durable against the solvent, indicator, and titrator, respectively.

[0052] Since the injection volume and injection rate of the solvent, indicator, and titrant are precisely controlled by the dispensing control unit (40), the present invention enables efficient analytical procedures and allows for the acquisition of highly accurate analytical results.

[0053] Pump control unit According to the present invention, the pump control unit (50) includes a solvent supply pump (51) for supplying solvent to a solvent dispenser (41), and a cooling solvent supply pump (52) for supplying cooling solvent to a cooling solvent injection tube (23).

[0054] In addition, the pump control unit (50) may further include a washing solvent supply pump (53) for supplying washing solvent to the washing solvent injection tube (34).

[0055] The solvent supply pump (51), the cooling solvent supply pump (52), and the washing solvent supply pump (53) are not particularly limited as long as they are pumps capable of transporting each respective solvent.

[0056] Since the pump control unit (50) controls the supply and flow rate of each solvent, the present invention can automate the analytical procedure.

[0057] Automatic data processing unit According to the present invention, the automatic data processing unit (60) includes software (61) for analyzing changes in potential values, and an output device (62) for outputting the analysis results obtained by the software.

[0058] In detail, the automated data processing unit (60) may be a commonly known computer. The automated data processing unit (60) is connected by wire or wireless to each of the sample supply unit (10), heating unit (20), titration unit (30), dispensing control unit (40), and pump control unit (50). Therefore, it is possible to set (control) the operating conditions that must be applied when each unit is operating.

[0059] In the automated analysis system according to the present invention, since the heating unit (20) and the titration unit (30) are separated, the colorimetric electrode (33) is not subjected to heat during the heating procedure, and thus the durability of the colorimetric electrode (33) is not degraded by heat. In addition, the polymer sample dissolution procedure, cooling procedure, titration procedure, and cleaning procedure of the test equipment used are all performed automatically, and therefore, an optimal analytical environment and reliable analytical results can be provided to the tester.

[0060] Embodiments of the Invention The present invention will be described in more detail below with reference to embodiments. However, these embodiments are provided for illustrative purposes only, and the present invention is not limited to these examples.

[0061] Example 1 PET semi-dull tips were selected as polymer samples, and the automated analysis system shown in Figure 2 was used to automatically analyze the content of carboxyl groups attached as PET end groups. Specifically, the PET semi-dull tips were placed in disposable polypropylene containers, which were attached to an autosampler.

[0062] Next, 60 ml of a mixed solvent containing o-cresol and chloroform in a 2:1 weight ratio was poured into a disposable container, and the mixture was heated at 65°C for 500 seconds to obtain the PET solution.

[0063] Next, 10 ml of chloroform was injected to cool the resulting PET solution and clean the heating rod.

[0064] Next, the titration conditions were set according to the Mettler Toledo titration program, and the cooled PET solution was titrated to calculate the carboxyl group content. Bromophenol blue was used as the indicator, and a 0.1N NaOH solution was used as the titrant.

[0065] Subsequently, the carboxyl group content analysis procedure was repeated for four days to collect analytical data. The results are shown in Table 1 below.

[0066] Example 2 The carboxyl group content was automatically analyzed using the same procedure as in Example 1, except that a PET BR chip was used instead of a PET semi-dull chip as the polymer sample. The results are shown in Table 1 below.

[0067] [Table 1] Referring to Table 1 above, the automated analysis of the PET sample confirmed that the carboxyl group (COOH) content was within the conventional control range for carboxyl group (COOH) content. This supports the fact that reliable analytical results can be obtained by analyzing the polymer end group content using the automated analysis method (system) according to the present invention.

[0068] Example 3 The carboxyl group content was automatically analyzed using the same procedure as in Example 1, except for various changes in the type of polymer sample. The results are shown in Table 2 below.

[0069] [Table 2] Referring to Table 2 above, when the carboxyl group (COOH) content of various polymer samples was analyzed using the automated analysis method (system) according to the present invention, it can be confirmed that the analysis was performed well, with the deviation of the carboxyl group content being within a range that was not large. [Explanation of Reference Symbols]

[0070] 10 Sample supply units 11 Autosampler 12 containers 20 Heating Units 21 Solvent injection tube 22 heating rod 23 Cooling solvent injection tube 30 titration units 31 Indicator infusion tube 32 Titrate injection tubes 33 Colorimetric electrode 34 Washing solvent injection tube 40 Dispensing Control Unit 41 Solvent dispenser 42 Indicator dispenser 43 Titrate dispenser 50 Pump control unit 51 Solvent supply pump 52 Cooling solvent supply pump 53 Washing solvent supply pump 60 Automatic Data Processing Units 61 Software 62 Output Devices

Claims

1. (1) The step of attaching a container containing the polymer sample to the autosampler, (2) A step of adding a solvent containing an aromatic compound having at least one hydroxyl group to the container containing the polymer sample and heating it to obtain a polymer sample solution, (3) The step of cooling the polymer sample solution, (4) Add an indicator to the cooled polymer sample solution and titrate it with a titrator, observing the change in the potential value of the colorimetric electrode. (5) A step of analyzing the change in the potential value using software to calculate the content of polymer end groups, An automated method for analyzing polymer end groups, including [specific group name].

2. The method for automated analysis of polymer end groups according to claim 1, wherein the aromatic compound in step (2) comprises at least one selected from the group consisting of phenol, o-cresol, m-cresol, p-cresol, o-chlorophenol, m-chlorophenol, p-chlorophenol, 2,6-xylenol, catechol, resorcinol, hydroquinone, pyrogallol, and benzyl alcohol.

3. The method for automated analysis of polymer end groups according to claim 1, wherein the solvent in step (2) further comprises at least one auxiliary solvent selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol.

4. The method for automated analysis of polymer end groups according to claim 3, wherein the mixing ratio of the aromatic compound to the auxiliary solvent is 5:1 to 1:

5.

5. The method for automated analysis of polymer end groups according to claim 1, wherein the heating in step (2) is performed at 60 to 100°C for 400 to 900 seconds.

6. The method for automated analysis of polymer end groups according to claim 1, wherein the cooling in step (3) is performed by injecting at least one cooling solvent selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol into the polymer sample solution.

7. The method for automated analysis of polymer end groups according to claim 6, wherein a heating rod used to heat the polymer sample into which the solvent has been injected is washed with the cooling solvent in step (3).

8. The method for automated analysis of polymer end groups according to claim 1, wherein the indicator in step (4) comprises at least one selected from the group consisting of bromophenol blue, phenol red, and methyl red.

9. The method for automated analysis of polymer end groups according to claim 1, wherein the titrant in step (4) comprises at least one selected from the group consisting of sodium hydroxide (NaOH) and potassium hydroxide (KOH).

10. (6) The method for automated analysis of polymer end groups according to claim 1, further comprising the step of washing the colorimetric electrode of step (4) by supplying a washing solvent.

11. The method for automated analysis of polymer end groups according to claim 10, wherein the washing solvent is at least one selected from the group consisting of acetone, acetonitrile, isopropanol, and water.

12. The method for automated analysis of polymer end groups according to claim 1, wherein the polymer is a polymer having a carboxyl group.

13. The method for automated analysis of polymer end groups according to claim 1, wherein the end group is a carboxyl group (COOH).

14. A sample supply unit equipped with an autosampler to which a container containing a polymer sample is attached, A heating unit comprising a solvent injection tube for injecting a solvent containing an aromatic compound having at least one hydroxyl group into the container containing the polymer sample, a heating rod for heating the polymer sample into which the solvent has been injected, and a cooling solvent injection tube for injecting a cooling solvent for cooling the polymer sample solution obtained by the heating, A titration unit comprising an indicator injection tube for injecting an indicator into the polymer sample solution cooled by the cooling solvent, a titrant injection tube for injecting a titrant into the polymer sample solution into which the indicator has been injected, and a colorimetric electrode that shows a change in potential value according to the amount of titrant injected, A dispensing control unit comprising a solvent dispenser for dispensing the solvent into the solvent injection tube, an indicator dispenser for dispensing the indicator into the indicator injection tube, and a titrator dispenser for dispensing the titrator into the titrator injection tube, A pump control unit comprising a solvent supply pump for supplying the solvent to the solvent dispenser, and a cooling solvent supply pump for supplying the cooling solvent to the cooling solvent injection tube, An automatic data processing unit comprising software for analyzing the changes in the aforementioned potential value, and an output device for outputting the analysis results obtained by the software, An automated analysis system for polymer end groups.

15. The automated analysis system for polymer end groups according to claim 14, wherein the container containing the polymer sample is a disposable container.

16. The automated analysis system for polymer end groups according to claim 14, wherein the solvent further comprises at least one auxiliary solvent selected from the group consisting of chloroform, dichloromethane, and isopropyl alcohol.

17. The automated analysis system for polymer end groups according to claim 14, wherein the colorimetric electrode is a photometric sensor electrode (optrode).

18. The titration unit further comprises a washing solvent injection tube for injecting a washing solvent for washing the colorimetric electrode, The automated analysis system for polymer end groups according to claim 14, wherein the pump control unit further comprises a washing solvent supply pump for supplying the washing solvent to the washing solvent injection tube.

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