Hygroscopic composition and cosmetic

Abstract

Development of moisturizing ingredients that can sufficiently improve the water-retaining capacity of the stratum corneum, the skin's barrier layer. [Solution] A cosmetic containing (A) sucrose and (B) sodium chloride.

Description

[Technical Field]

[0001] The present invention relates to a composition and a cosmetic having hygroscopic properties. [Background technology]

[0002] Because moisture plays a vital role in maintaining youthful skin, cosmetics contain a variety of moisturizing ingredients, such as pyrrolidone carboxylate, a type of natural moisturizing factor, intercellular lipid components, oily components, polyhydric alcohols, and sodium hyaluronate (Non-Patent Document 1). [Prior art documents] [Non-patent literature]

[0003] [Non-Patent Document 1] Takeo Mitsui, Moisturizers, New Cosmetics (Nanzando), pp. 143-147 (1993) Summary of the Invention [Problem to be solved by the invention]

[0004] However, conventionally used moisturizing ingredients are not capable of sufficiently improving the water-retaining ability of the stratum corneum, which is the barrier layer of the skin, and the development of even better moisturizing ingredients is desired. [Means for solving the problem]

[0005] Therefore, the present inventors have measured the moisture absorption capacity of components that can easily penetrate the skin and have found that when a composition has excellent deliquescence, it significantly improves the moisturizing state of the stratum corneum, and when the composition is applied to the skin, an excellent moist feeling is obtained. They also found the composition ratio for a mixture of sucrose and sodium chloride to absorb moisture from the air and deliquesce at a humidity of 72% RH or less, and further found that adding serine to sucrose and sodium chloride would enable the mixture to absorb moisture from the air and deliquesce at a humidity of 67% RH or less.

[0006] That is, one aspect of the present invention is a composition containing (A) sucrose and (B) sodium chloride, and having a deliquescence onset humidity at 20°C of 72% RH or less. Another embodiment of the present invention is a composition containing (A) sucrose, (B) sodium chloride, and (C) serine, the composition having a deliquescence onset humidity at 35°C of 67% RH or less. Another embodiment of the present invention is a moisture absorbent composition or a moisturizing composition containing (A) sucrose and (B) sodium chloride. Another embodiment of the present invention is a moisture absorbent composition or a moisturizing composition containing (A) sucrose, (B) sodium chloride, and (C) serine. Another embodiment of the present invention is a cosmetic comprising (A) sucrose and (B) sodium chloride. Another aspect of the present invention is a cosmetic preparation containing (A) sucrose, (B) sodium chloride, and (C) serine. [Effects of the Invention]

[0007] The composition of the present invention has high moisture absorption capacity and is useful in various fields as a moisture absorbent, desiccant, moisturizer, etc. Furthermore, a cosmetic containing the composition of the present invention is a cosmetic having a good feel when used, which significantly improves the moisturizing state of the stratum corneum and imparts an excellent moist feeling to the skin to which it is applied. [Brief explanation of the drawings]

[0008] [Figure 1] FIG. 1 is a diagram showing criteria for determining deliquescence. [Figure 2] FIG. 1 is a diagram showing the range in which excellent deliquescence and water absorption properties are obtained when the results of Table 1 are plotted as a three-phase diagram. [Figure 3] FIG. 1 is a diagram showing the range in which excellent deliquescence and water absorption properties are obtained when the results of Table 2 are plotted as a three-phase diagram. [Figure 4] FIG. 1 is a diagram showing the range in which better deliquescence and water absorption properties are obtained when the results of Table 2 are plotted as a three-phase diagram. [Figure 5]FIG. 1 shows the effect of a composition (aqueous solution) containing sucrose, sodium chloride, and serine on the moisture content of the stratum corneum. [Figure 6] This figure shows the change in stratum corneum moisture content after 1 hour and 8 hours for the cases of a single component (sucrose), a two-component (sucrose and sodium chloride), and a three-component (sucrose, sodium chloride, and serine) formulation. Red: molar amount as in Example 1. Blue: molar amount as in Example 8. DETAILED DESCRIPTION OF THE INVENTION

[0009] Terms used in this specification are used in the sense commonly used in the art unless otherwise specified.

[0010] In this specification, deliquescence refers to the phenomenon in which a substance absorbs moisture from the air and spontaneously becomes an aqueous solution. In other words, a substance with high deliquescence can spontaneously hold water and can be said to have a high water retention capacity. The deliquescence onset humidity refers to the relative humidity at which a test component or a mixture of test components begins to deliquesce. Here, the conditions for measuring the deliquescence onset humidity are 20°C to 35°C and 1 atmosphere. Specifically, the condition of 72% RH is 20°C, and the condition of 67% RH is 35°C. More specifically, the test components (total amount of (A), (B), and (C)) were mixed in powder form, and if the water absorption amount was 0.015 g or more per 1000 μmol of the test components over three days at 72% RH, it was determined that there was deliquescence.Furthermore, if the water absorption amount was 0.015 g or more per 1000 μmol of the test components over three days at 67% RH, it was determined that there was high deliquescence.

[0011] One aspect of the present invention is a composition containing (A) sucrose and (B) sodium chloride, which has a deliquescence onset humidity at 20°C of 72% RH or less. The component (A) contained in the composition of the present invention is sucrose. Sucrose, also known as sucrose, is a disaccharide in which glucose and fructose are linked by an α-1,2-glycosidic bond. Sucrose alone does not exhibit deliquescent properties. Sodium chloride (B) is a chloride of sodium and is known to deliquesce at a relative humidity of approximately 80%, but it is not known that mixing it with sucrose in a specific ratio reduces the humidity at which deliquescence begins. As described in the Examples below, a mixture of (A) sucrose and (B) sodium chloride absorbs moisture from the air and deliquesces at a relative humidity of 72%. Therefore, one aspect of the present invention is a composition containing (A) sucrose and (B) sodium chloride, which has a deliquescence onset humidity of 72% or less. Furthermore, a composition containing (A) sucrose and (B) sodium chloride has excellent deliquescent properties, and therefore absorbs water, making it useful as a moisture absorbent. Therefore, another aspect of the present invention is a moisture absorbent composition containing (A) sucrose and (B) sodium chloride. Due to the same effect, the composition can also be used as a moisturizer.

[0012] The molar ratio (A / B) of component (A) to component (B) in the composition of the present invention is preferably 0.1 or more and 10 or less, more preferably 0.2 or more and 6 or less, and even more preferably 0.25 or more and 5 or less, from the viewpoint of obtaining excellent deliquescence. From the viewpoint of obtaining excellent deliquescence, the total content of component (A) and component (B) in the composition of the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 0.4% by mass or more, and even more preferably 0.5% by mass or more, with the upper limit of this total amount being 100% by mass.

[0013] The composition of the present invention can contain various components as long as they do not adversely affect the deliquescence. However, if component (A) and component (B) are present in a particulate state, they need only be in contact with each other. Furthermore, as long as the component does not excessively absorb the surrounding moisture, various other components can be present together. For example, various porous carriers, acids, bases, etc. can be present together.

[0014] Another embodiment of the present invention is a composition containing (A) sucrose, (B) sodium chloride, and (C) serine, the composition having a deliquescence onset humidity at 35°C of 67% RH or less. Here, serine is a type of amino acid that is not known to have deliquescent properties, and L-serine is preferred as serine. As described in the Examples below, when serine is added to sucrose and sodium chloride, the composition absorbs moisture from the atmosphere and deliquesces at a humidity of 67% RH or less. Therefore, one aspect of the present invention is a composition containing (A) sucrose, (B) sodium chloride, and (C) serine, and having a deliquescence onset humidity of 67% RH or less at 35°C. Furthermore, a composition containing (A) sucrose, (B) sodium chloride, and (C) serine has excellent deliquescent properties and is therefore useful as a moisture absorbent or moisturizing agent. Therefore, another aspect of the present invention is a moisture absorbent composition or moisturizing agent composition containing (A) sucrose, (B) sodium chloride, and (C) serine.

[0015] In order to obtain excellent deliquescence, water absorption, hygroscopicity, and moisture retention, the molar ratio percentages of component (A) as (X), component (B) as (Y), and component (C) as (Z) in the composition of the present invention are determined to be in the range of the following coordinates in a ternary phase diagram: It is preferable that the range is within the range of (X, Y, Z) = (90, 10, 0), (10, 10, 80), (10, 90, 0), (X,Y,Z)=(70,20,10), (50,20,30), (50,10,40), (10,10,80), (10,80,10) It is more preferable that the range is within the range enclosed by (X,Y,Z)=(50,40,10), (50,20,30), (20,20,60), (20,70,10) It is more preferable that the range is within the range enclosed by . The molar ratio ((A)+(B)+(C)) / (A) of the total amount of components (A), (B) and (C) to the content of component (A) in the composition of the present invention is preferably 1 or more and 10 or less, more preferably 1.5 or more and 7 or less, and even more preferably 2 or more and 4 or less, from the viewpoint of obtaining excellent deliquescence, water absorption, hygroscopicity and moisture retention. Furthermore, from the viewpoint of obtaining excellent deliquescence, water absorption, hygroscopicity, and moisture retention, the total content of components (A), (B), and (C) in the composition of the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 0.4% by mass or more, and even more preferably 0.5% by mass or more. The upper limit of this total amount is 100% by mass. More specifically, the total amount is more preferably 0.05% by mass or more and 20% by mass or less, and even more preferably 0.5% by mass or more and 3% by mass or less. The total molar amount of components (A), (B), and (C) in the moisture-absorbent composition of the present invention is preferably 500 μmol or more, and more preferably 800 μmol or more, from the viewpoint of obtaining sufficient deliquescence, water absorption, and hygroscopicity. When the moisture-absorbent composition is in the form of fractions or individual forms such as capsules, from the viewpoint of ensuring surface area, the molar amount refers to the molar amount of each fraction or individual form. There is no particular upper limit to the total molar amount of components (A), (B), and (C) in the moisture-absorbent composition, but considering a convenient form, it is preferably 300 mmol or less, more preferably 30 mmol or less.

[0016] The composition of the present invention can contain various components as long as they do not adversely affect deliquescence, water absorption, hygroscopicity, or moisture retention. However, if components (A), (B), and (C) are present in particulate form, these three components need only be in contact with each other. Furthermore, as long as the components do not excessively absorb the surrounding moisture, they can coexist with various other components. For example, various porous carriers, acids, bases, etc. can coexist.

[0017] Another embodiment of the present invention is a cosmetic comprising (A) sucrose and (B) sodium chloride. As shown in the examples below, cosmetics containing these components (A) and (B) significantly improve the moisturizing state of the stratum corneum, and when applied to the skin, the cosmetics provide an excellent moist feeling.

[0018] The molar ratio (A / B) of component (A) to component (B) in the cosmetic of the present invention is preferably 0.1 or more and 10 or less, more preferably 0.2 or more and 5 or less, and even more preferably 0.25 or more and 4 or less, from the viewpoint of improving the moisturizing state of the stratum corneum. From the viewpoint of improving the moisturizing state of the stratum corneum, the total content of components (A) and (B) in the cosmetic of the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 0.4% by mass or more, and even more preferably 0.5% by mass or more. The upper limit of this total amount is preferably 15% by mass or less, more preferably 10% by mass or less, even more preferably 5% by mass or less, and even more preferably 2% by mass or less.

[0019] Another embodiment of the present invention is a cosmetic comprising (A) sucrose, (B) sodium chloride, and (C) serine. As shown in the examples below, cosmetics containing these components (A), (B), and (C) significantly improve the moisturizing state of the stratum corneum, and when applied to the skin, the cosmetics provide an excellent moist feeling and can maintain this effect. The addition of serine to components (A) and (B) can further moisturize the skin over time.

[0020] In terms of improving the moisturizing state of the stratum corneum, the molar ratio percentages of component (A) as (X), component (B) as (Y), and component (C) as (Z) in the cosmetic of the present invention are preferably within the range surrounded by the following coordinates (X, Y, Z) = (90, 10, 0), (10, 10, 80), and (10, 90, 0) in a ternary phase diagram, (X,Y,Z)=(70,20,10), (50,20,30), (50,10,40), (10,10,80), (10,80,10) It is more preferable that the range is within the range enclosed by (X,Y,Z)=(50,40,10), (50,20,30), (20,20,60), (20,70,10) It is more preferable that the range is within the range enclosed by .

[0021] The content of component (A) in the present invention is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, and even more preferably 0.5% by mass or more from the viewpoint of moist feeling, and is preferably 10% by mass or less, more preferably 5% by mass or less, and even more preferably 2% by mass or less from the viewpoint of feeling in use (reducing stickiness on the skin). In the present invention, the content of component (B) is preferably 0.02% by mass or more, more preferably 0.04% by mass or more, even more preferably 0.05% by mass or more, and even more preferably 0.1% by mass or more from the viewpoint of moist feeling, and is preferably 10% by mass or less, more preferably 3% by mass or less, even more preferably 1% by mass or less, and even more preferably 0.4% by mass or less from the viewpoint of reducing skin irritation. The content of component (C) in the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, and even more preferably 0.2% by mass or more, from the viewpoint of moist feeling and improving moisture content in the skin for a long time. Also, from the viewpoint of the feeling during use (reducing the feeling of tightness on the skin), it is preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 2% by mass or less, and even more preferably 0.8% by mass or less. The molar ratio ((A) + (B) + (C)) / (A) of the total amount of components (A), (B) and (C) to the content of component (A) in the cosmetic of the present invention is preferably 1 or more and 10 or less, more preferably 1.5 or more and 7 or less, and even more preferably 2 or more and 4 or less, from the viewpoint of improving the moisturizing state of the stratum corneum. From the viewpoint of improving the moisturizing state of the stratum corneum, the total content of components (A), (B), and (C) in the cosmetic of the present invention is preferably 0.16% by mass or more, more preferably 0.2% by mass or more, even more preferably 0.25% by mass or more, and even more preferably 0.7% by mass or more. The upper limit of this total amount is preferably 20% by mass or less, more preferably 10% by mass or less, even more preferably 5% by mass or less, and even more preferably 3% by mass or less. The mass ratio ((A) + (B)) / (C) of the total content of components (A) and (B) to the content of component (C) in the cosmetic of the present invention is preferably 0.5 or more, more preferably 1 or more, and more preferably 2 or more, from the viewpoint of improving moist feeling and long-lasting moisture content on the skin. Furthermore, from the viewpoint of improving the feeling during use, such as a squeaky feeling, this mass ratio is preferably 25 or less, more preferably 20 or less, and more preferably 10 or less.

[0022] The cosmetic preparation of the present invention may be in any form as long as it contains the components (A) and (B), or the components (A), (B), and (C) in an aqueous phase, and examples of such forms include aqueous cosmetics such as lotions and emulsions, oil-in-water emulsion cosmetics, and water-in-oil cosmetics.

[0023] In addition to components (A), (B), and (C), the cosmetic composition of the present invention may contain surfactants, polyhydric alcohols, thickeners, oils, water, monohydric alcohols such as ethanol, preservatives, antioxidants, pigments, pH adjusters, fragrances, plant extracts, colorants, powders, UV absorbers, other moisturizers, blood circulation promoters, cooling agents, antiperspirants, disinfectants, skin activators, and the like.

[0024] As the surfactant, an ionic surfactant or a nonionic surfactant can be used. Examples of nonionic surfactants include polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene alkanol ethers, polyglycerin fatty acid esters, sucrose fatty acid esters, polyoxyethylene sorbitan beeswax, glycolipids, etc. Among these, from the viewpoints of emulsion stability and usability, it is preferable to contain one or more selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ethers, and polyoxyethylene fatty acid esters, more preferably to contain one or more selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene alkyl ethers, and even more preferably to contain polyoxyethylene hydrogenated castor oil. Examples of ionic surfactants include hydrogenated soybean phospholipid, egg yolk lecithin, acyl glutamate, sodium surfactin, and acyl sulfate.

[0025] When the cosmetic of the present invention is an oil-in-water emulsion composition, it is preferable to use a nonionic surfactant. The HLB of the nonionic surfactant is preferably 9 to 18, and from the viewpoint of causing a change in the feel of the cosmetic during application, an HLB of 11 to 16 is more preferable, and an HLB of 12 to 15 is even more preferable. Furthermore, when the cosmetic of the present invention is a water-in-oil emulsion composition, it is preferable to use a nonionic surfactant. The HLB of the nonionic surfactant is preferably 1 to 9, more preferably 2 to 8, and even more preferably 3 to 7.

[0026] Here, HLB (Hydrophilic-Lipophilic Balance) indicates the molecular weight of the hydrophilic group portion relative to the total molecular weight of the surfactant, and is calculated using Griffin's equation. Furthermore, when a surfactant is composed of two or more nonionic surfactants, the HLB of the mixed surfactant is calculated as follows: The HLB of the mixed surfactant is the arithmetic average of the HLB values ​​of each nonionic surfactant based on their blending ratio. Mixed HLB=Σ(HLBx×Wx) / ΣWx HLBx indicates the HLB value of nonionic surfactant X. Wx represents the mass (g) of the nonionic surfactant X having the value of HLBx.

[0027] The surfactants can be used alone or in combination of two or more. From the viewpoints of improving emulsion stability, improving spreadability upon application, and improving the feel upon use, the content is preferably 0.05 to 6 mass % of the total composition, more preferably 0.1 to 5 mass %, even more preferably 0.3 to 4 mass %, and even more preferably 0.5 to 3.5 mass %.

[0028] When the cosmetic of the present invention is an emulsion composition, the water content is preferably 20 to 99% by mass, more preferably 35 to 98% by mass, of the total composition.

[0029] When the cosmetic of the present invention is made into an emulsion composition, it can further contain a polyhydric alcohol, which can improve spreadability upon application and improve the feel when used. Note that the polyhydric alcohol of the present invention does not contain component (A) sucrose, but is a polyhydric alcohol other than component (A). The polyhydric alcohol is a compound having two or more hydroxyl groups in the molecule, and any of those commonly used in cosmetics may be used. Examples of dihydric alcohols include ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, polypropylene glycol, butylene glycol, and propanediol. Examples of trihydric alcohols include glycerin and trimethylolpropane. Examples of tetrahydric alcohols include diglycerin and erythritol. Examples of pentahydric or higher polyhydric alcohols include polyglycerins such as triglycerin; and sugars and sugar alcohols other than sucrose, such as glucose, maltose, maltose, xylitol, sorbitol, malbitol, trehalose, polyoxyethylene methyl glucoside, polyoxyethylene ethyl glucoside, and polyoxyethylene propylene glucoside.

[0030] The polyhydric alcohols can be used alone or in combination of two or more. From the viewpoint of improving spreadability during application and improving the feel during use, the content is preferably 0.5 to 50 mass %, more preferably 1 to 40 mass %, and even more preferably 2 to 30 mass % of the total composition.

[0031] The cosmetic of the present invention may further contain a thickener, which can improve emulsion stability, improve spreadability upon application, and improve the feel upon use. The thickener increases the viscosity of the cosmetic by swelling in the continuous phase, water or oil, and may be any of those commonly used in external skin preparations. Examples of thickeners include polysaccharides such as xanthan gum, carrageenan, and Tremella fuciformis polysaccharide; modified polysaccharides such as carboxymethylated glucan, hydroxypropylmethylcellulose, and ethylcellulose; and synthetic polymers such as carboxyvinyl polymers, acyl-modified carboxyvinyl polymers, and sodium polyacrylate.

[0032] The content of the thickener in the total composition is preferably 0.001 to 1.5% by mass, more preferably 0.005 to 1.0% by mass, and even more preferably 0.01 to 0.7% by mass, from the viewpoints of improving emulsion stability, improving spreadability upon application, and improving the feel when used.

[0033] The oil used in the cosmetic of the present invention is preferably an oil that is liquid at 25° C. Liquid means that it has fluidity, and includes paste-like forms. Oils that are liquid at 25°C include those commonly used in cosmetics, such as hydrocarbon oils, ester oils, ether oils, silicone oils, and higher fatty acids.

[0034] Examples of hydrocarbon oils include squalane, liquid paraffin, liquid isoparaffin, light liquid isoparaffin, heavy liquid isoparaffin, and α-olefin oligomers. The hydrocarbon oil preferably contains one or more selected from squalane and α-olefin oligomers, and more preferably contains squalane.

[0035] Ester oils include monoester oils, diester oils, triester oils and tetraester oils. Examples of monoester oils include monoesters of aliphatic or aromatic monocarboxylic or dicarboxylic acids having 2 to 24 carbon atoms, and specific examples thereof include cetyl 2-ethylhexanoate, cetyl octanoate, isononyl isononanoate, isotridecyl isononanoate, hexyl laurate, isopropyl myristate, octyldodecyl myristate, myristyl myristate, 2-hexyldecyl myristate, isopropyl palmitate, octyl palmitate, and the like. Examples of suitable oils include ethylhexyl palmitate, 2-hexyldecyl butyl stearate, isocetyl stearate, isocetyl isostearate, decyl oleate, isodecyl benzoate, octyl methoxycinnamate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, 2-ethylhexyl succinate, 2-hexyldecyl adipate, alkyl benzoate (C12 to C15), ethylhexyl methoxycinnamate, and jojoba oil. The monoester oil preferably contains one or more selected from ethylhexyl methoxycinnamate and jojoba oil, and more preferably contains jojoba oil.

[0036] Examples of diester oils include diesters of dicarboxylic acids having 3 to 18 carbon atoms and difatty acid esters of polyhydric alcohols. Specific examples include propylene glycol dicaprylate, neopentyl glycol dicaprate, glycol distearate, propylene glycol diisostearate, glyceryl diisostearate, glyceryl monomyristate monoisostearate, glycerin di-2-heptylundecanoate, di-2-ethylhexyl succinate, diisopropyl sebacate, diisostearyl malate, ethylene glycol di-2-ethylhexanoate, diisobutyl adipate, di-2-heptylundecyl adipate, and di-2-ethylhexyl sebacate.

[0037] Triester oils include tri-fatty acid esters of trivalent or higher polyhydric alcohols, and specific examples include glyceryl triisopalmitate, glyceryl tri-2-heptylundecanoate, trimethylolpropane triethylhexanoate, trimethylolpropane trioctanoate, tri(caprylic / capric)glyceryl, glyceryl trioleate, glyceryl tri-2-ethylhexanoate, glyceryl triisostearate, and vegetable oils such as olive oil, macadamia nut oil, meadowfoam oil, castor oil, safflower oil, sunflower oil, avocado oil, canola oil, apricot kernel oil, rice germ oil, and rice bran oil. The triester oil preferably contains one or more selected from vegetable oils, more preferably contains one or more selected from olive oil and macadamia nut oil, and even more preferably contains olive oil.

[0038] Examples of tetraester oils include tetra-fatty acid esters of tetrahydric or higher polyhydric alcohols, and specific examples include pentaerythritol tetra(behenate / benzoate / ethylhexanoate), pentaerythritol tetraethylhexanoate, pentaerythritol tetraoctanoate, and pentaerythritol tetra-2-ethylhexanoate.

[0039] The ether oils include dialkyl ethers, and specific examples thereof include dihexyl ether, dicaprylyl ether, and cetyl-1,3-dimethylbutyl ether.

[0040] Examples of silicone oils include volatile and non-volatile linear dimethylpolysiloxanes such as dimethylpolysiloxane (1cs), dimethylpolysiloxane (1.5cs), dimethylpolysiloxane (2cs), dimethylpolysiloxane (6cs), dimethylpolysiloxane (20cs), and dimethylpolysiloxane (100cs); branched siloxanes such as methyltrimethicone, tris(trimethylsilyl)methylsilane, and tetrakis(trimethylsilyl)silane; cyclic dimethylsiloxanes such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane; crosslinked methylpolysiloxanes, reticular methylpolysiloxanes, methylphenylpolysiloxanes such as methyltrimethicone and diphenylsiloxyphenyltrimethicone, and higher alcohol-modified organopolysiloxanes. The silicone oil preferably contains one or more selected from linear dimethylpolysiloxanes and methylphenylpolysiloxanes, more preferably one or more selected from non-volatile linear dimethylpolysiloxanes and methylphenylpolysiloxanes, and even more preferably methylphenylpolysiloxanes.

[0041] Examples of higher fatty acids include oleic acid, isostearic acid, and undecylenic acid.

[0042] From the viewpoint of usability, the oil agent that is liquid at 25°C preferably contains one or more selected from hydrocarbon oils, ester oils, ether oils, and silicone oils, more preferably contains hydrocarbon oils, ester oils, and silicone oils, even more preferably contains one or more selected from hydrocarbon oils, monoester oils, triester oils, and silicone oils, still more preferably contains one or more selected from squalane, ethylhexyl methoxycinnamate, olive oil, macadamia nut oil, jojoba oil, and methylphenylpolysiloxane, and particularly preferably contains one or more selected from squalane, olive oil, jojoba oil, and methylphenylpolysiloxane.

[0043] The content of the oil agent that is liquid at 25°C is preferably 0.1 to 95% by mass, more preferably 0.5 to 80% by mass, and even more preferably 1 to 75% by mass of the total composition, from the viewpoints of improving emulsion stability, improving spreadability upon application, and improving the feel during use.

[0044] The cosmetic of the present invention can be produced by a conventional method. For example, it can be produced by appropriately mixing the specified ingredients, and can be produced by uniformly mixing and dispersing all ingredients, regardless of the mixing order. In particular, it can be prepared by low-energy production using little mechanical force in an environment of 40°C or less.

[0045] The cosmetic of the present invention can be applied to cosmetics, medicated cosmetics that are quasi-drugs, etc., and is more preferably applied as a skin care cosmetic.

[0046] In relation to the above-described embodiment, the present invention further discloses the following compositions, etc. <1> A cosmetic comprising (A) sucrose and (B) sodium chloride. <2> The molar ratio (A / B) of the component (A) to the component (B) is 0.1 or more and 10 or less. <1> The cosmetic product described. <3> A cosmetic preparation containing (A) sucrose, (B) sodium chloride, and (C) serine. <4> (A) sucrose, (B) sodium chloride, and (C) serine are contained within the range enclosed by the following coordinates in a ternary phase diagram: <1> ~ <3> 1. A cosmetic composition according to any one of the preceding claims. Molar ratio percentage of component (A) (X), component (B) (Y), and component (C) (Z) (X,Y,Z)=(90,10,0), (10,10,80), (10,90,0) <5> (A) sucrose, (B) sodium chloride, and (C) serine are contained within the range enclosed by the following coordinates in a ternary phase diagram: <4> The cosmetic product described. Molar ratio percentage of component (A) (X), component (B) (Y), and component (C) (Z) (X,Y,Z)=(70,20,10), (50,20,30), (50,10,40) , (10,10,80), (10,80,10) <6> The total content of components (A), (B), and (C) is 0.05% by mass or more and 20% by mass or less. <1> ~ <5> 1. A cosmetic composition according to any one of the preceding claims. <7> The total content of components (A), (B), and (C) is 0.5% by mass or more and 3% by mass or less. <1> ~ <5> 1. A cosmetic composition according to any one of the preceding claims. <8> Further, the composition contains one or more selected from a surfactant, water, a polyhydric alcohol, a thickener, and an oil. <1> ~ <7> 1. A cosmetic composition according to any one of the preceding claims. <9> A moisture absorbent composition comprising (A) sucrose and (B) sodium chloride. <10> The molar ratio (A / B) of the component (A) to the component (B) is 0.1 or more and 10 or less. <9> The moisture absorbent composition described above. <11> A moisture absorbent composition comprising (A) sucrose, (B) sodium chloride, and (C) serine. <12> (A) sucrose, (B) sodium chloride, and (C) serine are contained within the range enclosed by the following coordinates in a ternary phase diagram: <9> ~ <11> The moisture-absorbent composition according to any one of the preceding claims. Molar ratio percentage of component (A) (X), component (B) (Y), and component (C) (Z) (X,Y,Z)=(90,10,0), (10,10,80), (10,90,0) <13> (A) sucrose, (B) sodium chloride, and (C) serine are contained within the range enclosed by the following coordinates in a ternary phase diagram: <12> The moisture absorbent composition described above. Molar ratio percentage of component (A) (X), component (B) (Y), and component (C) (Z) (X,Y,Z)=(70,20,10), (50,20,30), (50,10,40) , (10,10,80), (10,80,10) <14> The total content of components (A), (B), and (C) is 0.16% by mass or more and 20% by mass or less. <9> ~ <13> The moisture-absorbent composition according to any one of the preceding claims. <15> The total content of components (A), (B), and (C) is 0.7% by mass or more and 3% by mass or less. <9> ~ <13> The moisture-absorbent composition according to any one of the preceding claims. [Example]

[0047] The present invention will now be described in more detail with reference to examples, but the present invention is not limited to these examples.

[0048] Test Example 1 Sucrose, serine, and sodium chloride were weighed out in a molar ratio (percentage) as shown in Table 1 so that the total amount was 1000 μmol, and then mixed uniformly in a 2.0 mL microtube. Next, a beaker containing a saturated aqueous solution of sodium chloride was placed inside the sealed chamber and left to stand at 20°C, creating a humidity environment of 72%. The microtube containing the mixture of sucrose, serine, and sodium chloride was left undisturbed in the 72% humidity environment for three days with the lid open, and then the weight was measured again. The weight before and after the suspension was subtracted, and the difference was taken as the amount of water absorbed. Regarding deliquescence, the appearance of the sample after standing was visually judged as shown in Figure 1 (×: no deliquescence observed, ◯: deliquescence observed, ◎: significant deliquescence observed). The results are shown in Table 1.

[0049] [Table 1]

[0050] Table 1 shows that although sucrose and sodium chloride do not exhibit deliquescence alone under these conditions (72% RH), the combination of sucrose and sodium chloride significantly improves deliquescence and water absorption. It was also found that the combination of serine and sodium chloride, or the combination of serine and sucrose, did not improve deliquescence. Furthermore, the combination of serine with sucrose and sodium chloride tended to improve deliquescence and water absorption. When the data in Table 1 is plotted on a three-phase diagram, as shown in FIG. 2, it can be seen that excellent deliquescence and improved water absorption can be obtained when the molar ratio percentages of component (A) (X), component (B) (Y), and component (C) (Z) are within the range surrounded by the following coordinates (X, Y, Z) = (90, 10, 0), (10, 10, 80), and (10, 90, 0) in the three-phase diagram.

[0051] Test Example 2 Sucrose, serine, and sodium chloride were weighed out in the molar ratios (percentages) shown in Table 2 so that the total amount was 1000 μmol, and then mixed uniformly in a 2.0 mL microtube. Next, a saturated aqueous solution of potassium iodide was placed in a sealed chamber and left to stand at 35°C, creating a humidity environment of 67%. The microtube containing the mixture of sucrose, serine, and sodium chloride was left in the 67% humidity environment for 3 days with the lid open, and then the water absorption and deliquescence were evaluated in the same manner as in Test Example 1. The results are shown in Table 2.

[0052] [Table 2]

[0053] From Table 2, it was found that under the condition of 67% RH, the combined use of sucrose, sodium chloride and serine significantly improved the deliquescence and water absorption. When the data in Table 2 are plotted on a ternary phase diagram, as shown in Figures 3 and 4, when the molar ratio percentages of the components (A) (X), (B) (Y), and (C) (Z) are within the range surrounded by the following coordinates (X, Y, Z) = (70, 20, 10), (50, 20, 30), (50, 10, 40), (10, 10, 80), and (10, 80, 10) in the ternary phase diagram, better deliquescence and improved water absorption are obtained. It can be seen that even better deliquescence and improved water absorption can be achieved within the ranges surrounded by (X, Y, Z) = (50, 40, 10), (50, 20, 30), (20, 20, 60), and (20, 70, 10).

[0054] Test Example 3 The effect of a composition (aqueous solution) containing sucrose, sodium chloride, and serine on the moisturizing state of the stratum corneum was measured using the moisture content of the stratum corneum as an index. Three subjects washed the inner forearms with a cleanser (Biore U Foaming Hand Soap, Kao) and then allowed to acclimate for 10 minutes at 25°C and 60% relative humidity. After acclimatization, the moisture content of the stratum corneum was measured using a Corneometer (Corneometer CM825, Integral). Next, 7 μL of each of (1) water, (2) 68 mM sucrose solution, or (3) a 68 mM sucrose + sodium chloride + serine solution (molar ratio 1:1:1) was uniformly applied to a 2 cm x 3 cm area. After 7 hours at 25°C and 60% relative humidity, the moisture content of the stratum corneum was measured again. The moisture content of the stratum corneum before application of the sample was subtracted from the moisture content of the stratum corneum 7 hours after application of the sample, and the difference was defined as the delta moisture content of the stratum corneum. The results are shown in Figure 5. As can be seen from Figure 5, the sucrose, sodium chloride, and serine combination group had a significantly higher stratum corneum moisture content after application than the water and sucrose alone groups, improving the moisturizing state of the stratum corneum.

[0055] Test Example 4 Approximately 0.05 mL of the lotions having the compositions shown in Tables 3 and 4 was applied to the backs of the hands of three subjects, and the moisturizing effect (moist feeling, absence of squeaky feeling) after application was evaluated. The composition of the lotion is shown in terms of mass concentration, molar concentration, and the molar amount when prepared so that the total volume is 0.1 L. The scores of each subject were averaged to calculate the average usability score. Moisture evaluation 4 points: Very moist 3 points: slightly moist 2 points: Not very moisturizing 1 point: Not moisturizing Squeakiness rating: 4 points: No creaking sensation 3 points: Slight creaking sensation 2 points: There is a slight creaking sensation 1 point: There is a creaking sensation

[0056] [Table 3]

[0057] [Table 4]

[0058] As can be seen from Tables 3 and 4, the lotions containing sucrose and sodium chloride and the lotions containing sucrose, sodium chloride and serine left the skin feeling moisturized, without any dryness or stinging, and had good moisturizing effects.

[0059] Test Example 5 The effect of a composition (aqueous solution) containing sucrose, sodium chloride, and serine on the moisturizing state of the stratum corneum was measured using the moisture content of the stratum corneum as an index. The moisture content of the stratum corneum was measured according to the "Method for Evaluating Moisture Content in the Stratum Corneum of Skin" in Patent No. 7642437, calculated from the peak of the infrared absorption spectrum of the stratum corneum after tape peeling. The specific test method is shown below. Three subjects washed the inside of their forearms with a cleanser (Biore U Foaming Hand Soap, Kao), and then allowed to acclimate for 10 minutes in an environment with a temperature of 25°C and a relative humidity of 60%. After acclimatization, adhesive tape (TF15-02, Azflon Tape, manufactured by AS ONE) was applied, and the stratum corneum was collected from the adhesive surface of the tape. Next, 10.5 μl of each of (1) water, (2) 60 mM sucrose solution, (3) 60 mM sucrose + sodium chloride solution (molar ratio 4:3), or (4) 60 mM sucrose + sodium chloride + serine solution (molar ratio 1:1:1) was uniformly applied to a 3 cm × 3 cm area, and the stratum corneum was sampled after 1 hour and 8 hours at 25°C and 60% relative humidity. The compositions of the water and aqueous solutions (lotions) used in the test are shown in Table 5. For each of the obtained stratum corneum samples, the infrared absorption spectrum of the stratum corneum was measured using the method described in Japanese Patent No. 764237, and the moisture content of the stratum corneum was calculated. The moisture content of the stratum corneum before application of the aqueous solution (0 hours) was set at 1, and the moisture content of the stratum corneum after 1 hour and 8 hours was calculated and compared between each sample. The results are shown in FIG.

[0060] [Table 5]

[0061] [Table 6]

[0062] The three-ingredient lotion, which added serine to the stratum corneum, showed a greater improvement in moisture content after 1 hour and 8 hours than the two-ingredient lotion, sucrose, and sodium chloride. This is also thought to affect the moisturizing effect even after a long period of time has passed since application.

[0063] [Table 7]

[0064] [Table 8]

[0065] [Table 9]

[0066] [Table 10]

[0067] [Table 11]

[0068] [Table 12]

[0069] [Table 13]

[0070] The lotions, emulsions, and creams in Tables 7 to 13 all left the skin feeling moisturized, without any dry or stinging sensation, and were preparations with good moisturizing effects.

Claims

1. A moisture absorbent composition comprising (A) sucrose and (B) sodium chloride.

2. 2. The moisture-absorbent composition according to claim 1, wherein the molar ratio (A / B) of the components (A) to (B) is 0.1 or more and 10 or less.

3. A moisture absorbent composition comprising (A) sucrose, (B) sodium chloride, and (C) serine.

4. The moisture-absorbent composition according to any one of claims 1 to 3, comprising (A) sucrose, (B) sodium chloride, and (C) serine within a range surrounded by the following coordinates in a ternary phase diagram: Molar ratio percentages of components (A) (X), (B) (Y), and (C) (Z) (X, Y, Z) = (90, 10, 0), (10, 10, 80), (10, 90, 0)

5. 5. The moisture-absorbing composition according to claim 4, comprising (A) sucrose, (B) sodium chloride, and (C) serine within the range enclosed by the following coordinates in a ternary phase diagram: Molar ratio percentages of components (A) (X), (B) (Y), and (C) (Z) (X, Y, Z) = (70, 20, 10), (50, 20, 30), (50, 10, 40), (10, 10, 80), (10, 80, 10)

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