Skin composition

Abstract

To provide a skin composition that allows a significant reduction in the ingredient smell of coenzyme Q10 and also a significant reduction in stickiness after its application.SOLUTION: A skin composition contains the following component A, the following component B, and the following component C. The content of the component A is more than 0.3 mass% and 1.0 mass% or less. The component A is coenzyme Q10, the component B is unsaturated fatty acid ester oil and the component C is an amino acid.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a composition for skin.

Background Art

[0002] One of the functions required for skincare preparations is "moisturization". Conventionally, for example, components constituting intercellular lipids of keratinocytes such as ceramide, sphingolipid, and lecithin; components present in keratinocytes such as natural moisturizing factor (NMF); components originally present in the dermis such as hyaluronic acid and collagen; various components exhibiting moisturizing effects such as polyhydric alcohols, oils, saccharides, and plant extracts have been formulated in the preparations.

[0003] Among such components, coenzyme Q10 has continued to attract attention as a component having extremely excellent moisturizing ability. However, while coenzyme Q10 can exhibit extremely excellent moisturizing ability, when formulated at a high concentration expecting a moisturizing effect, there are problems such as a prominent raw material odor, which hinders formulation, and a sticky feeling remaining after application.

[0004] Regarding the problem of the raw material odor, a method of masking the odor using a fragrance or the like can be considered, but imparting a fragrance to the preparation also depends on the user's olfactory preference and cannot be said to be the best improvement method. Therefore, the development of a method for suppressing the odor other than the masking method is required. So far, attempts have been made to suppress the odor change over time in preparations containing coenzyme Q10 (for example, refer to Patent Document 1). However, this attempt is aimed at suppressing the deterioration and odor change over time in an oily skin composition and has not led to a fundamental solution for suppressing the raw material odor of coenzyme Q10.

[0005] On the other hand, reducing stickiness necessitates a low concentration of coenzyme Q10, making it impossible to provide the desired moisturizing effect. Various attempts have been made to suppress stickiness in formulations containing coenzyme Q10 (see, for example, Patent Documents 2-3). However, these attempts have drawbacks, such as requiring ingenuity in formulation and being time-consuming to prepare. [Prior art documents] [Patent Documents]

[0006] [Patent Document 1] Japanese Patent Publication No. 2007-084505 [Patent Document 2] Japanese Patent Publication No. 2007-077084 [Patent Document 3] Japanese Patent Publication No. 2013-136545 [Overview of the project] [Problems that the invention aims to solve]

[0007] The present invention has been made in view of the above-mentioned prior art, and aims to provide a skin composition that can significantly reduce the raw material odor of coenzyme Q10 and significantly reduce the sticky feeling after application, even when coenzyme Q10 is included in a high concentration to fully exert its main function. [Means for solving the problem]

[0008] In other words, the present invention provides a skin composition containing the following component A, the following component B, and the following component C, wherein the content of component A is more than 0.3% by mass and 1.0% by mass or less. Ingredient A: Coenzyme Q10 Ingredient B: Unsaturated fatty acid ester oil Ingredient C: Amino Acids

[0009] It is preferable that the above component C is at least one selected from the group consisting of alanine, arginine, glycine, cysteine, serine, and ectoin.

[0010] The above skin composition preferably further contains the following component D. Ingredient D: Polyglycerin fatty acid ester type nonionic surfactant [Effects of the Invention]

[0011] The skin composition of the present invention, by satisfying the above constituent requirements, exhibits an odor-suppressing effect in an unprecedented manner, significantly reducing the raw material odor of coenzyme Q10. Furthermore, the skin composition of the present invention has the effect of significantly reducing the sticky feeling after application. [Modes for carrying out the invention]

[0012] The skin composition of the present invention is characterized by containing the following component A, component B, and component C. Ingredient A: Coenzyme Q10 Ingredient B: Unsaturated fatty acid ester oil Ingredient C: Amino Acids

[0013] The details of each component used in the skin composition of the present invention are described below.

[0014] [Component A] The above-mentioned component A is coenzyme Q10. Coenzyme Q10 is a compound also known as coenzyme Q10, CoQ10, ubiquinone, or ubicarenone. In this invention, by using component A, it is possible to provide the skin with significantly superior moisture, or so-called moisturizing effect, after application.

[0015] Furthermore, component A is not particularly limited, whether it is a single raw material or a mixed raw material with other components. In the present invention, component A can be a commercially available product. Examples of commercially available coenzyme Q10 include Solfonte Q10, Phytopresome Q10, Phytopresome Lipo-Q, and Presome Q10 (trade names, all manufactured by Nippon Seika Co., Ltd.).

[0016] The content of component A in the skin composition of the present invention is more than 0.3% by mass and 1.0% by mass or less. From the perspective of usability, it is more preferably 0.9% by mass or less. In the present invention, even if component A is formulated at a high level, specifically, more than 0.3% by mass, the raw material odor can be significantly reduced by combining it with the components described later. Further, in the present invention, since component A can be formulated at a high level, it is needless to say that it exhibits an extremely excellent moisturizing effect. The content of the above component A is the amount converted to the pure component.

[0017] [Component B] The above component B is an unsaturated fatty acid ester oil. In the present invention, surprisingly, by using the above component B, an extremely remarkable effect that has never been known conventionally, that is, the raw material odor of the above component A can be reduced, is exhibited. Therefore, even when the content of the above component A in the skin composition is more than 0.3% by mass, it is possible to reduce the raw material odor.

[0018] Examples of the above component B used include decyl oleate, oleyl oleate, octyldodecyl oleate, ethyl oleate, isodecyl oleate, cholesteryl oleate, dihydrocholesteryl oleate, phytosteryl oleate, and the like. These component Bs may be used alone or in appropriate combination of two or more.

[0019] In the present invention, among the above component Bs, from the perspective of significantly reducing the raw material odor of the above component A, it is preferable to use decyl oleate, oleyl oleate, and octyldodecyl oleate.

[0020] Incidentally, the above-mentioned component B is not particularly limited as long as the desired effect can be exhibited, whether it is a single raw material or a mixed raw material with other components. In the present invention, commercially available products can be used as the above-mentioned component B. Examples of commercially available products of decyl oleate include, for example, CETIOL V (trade name, manufactured by BASF Japan Ltd.), examples of commercially available products of oleyl oleate include, for example, SR CRODAMOL OO-LQ-(JP) (trade name, manufactured by Croda Japan Ltd.), and examples of commercially available products of octyldodecyl oleate include, for example, O.O.D. (trade name, manufactured by Shin-Ei Chemical Co., Ltd.).

[0021] The content of component B in the skin composition of the present invention is not particularly limited as long as the desired effect can be sufficiently exhibited. Usually, from the viewpoint of significantly reducing the raw material odor of the above-mentioned component A, it is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, in 100% by mass of the composition. Also, from the viewpoint of the feeling of use, it is preferably 1.0% by mass or less, more preferably 0.5% by mass or less, in 100% by mass of the composition. Incidentally, the content of the above-mentioned component B is the amount converted to the pure component.

[0022] In the present invention, from the viewpoint of significantly reducing the raw material odor of the above-mentioned component A, it is preferable to prepare by satisfying the ratio of the content of component B to component A (component B / component A) in the range of 0.01 to 20.0, more preferably in the range of 0.05 to 5.0, and even more preferably in the range of 0.1 to 1.5.

[0023] [Component C] The above-mentioned component C is an amino acid. In the present invention, surprisingly, by using the above-mentioned component C, a particularly remarkable effect that has never been known before can be exhibited, that is, the stickiness after application of the above-mentioned component A can be reduced. Therefore, even when the content of the above-mentioned component A in the skin composition is more than 0.3% by mass, it is possible to reduce the stickiness.

[0024] Examples of the above-mentioned component C used include simple amino acids such as glycine and alanine; basic amino acids such as lysine, arginine, and histidine; acidic amino acids such as aspartic acid and glutamic acid; amino acids with amide side chains such as asparagine and glutamine; amino acids with alcohol side chains such as serine and threonine; amino acids with sulfur atoms in their side chains such as cysteine ​​and methionine; amino acids with aromatic rings in their side chains such as phenylalanine, tyrosine, and tryptophan; aliphatic and hydrophobic amino acids such as valine, leucine, and isoleucine; and amino acids with ring-shaped side chains such as proline and ectoin. These components C may be used individually or in combination of two or more as appropriate.

[0025] In the present invention, among the above-mentioned component C, it is preferable to use at least one selected from the group consisting of alanine, arginine, glycine, cysteine, glutamic acid, glutamine, phenylalanine, leucine, serine, and ectoin, from the viewpoint of reducing excessive stickiness after application of component A, and it is more preferable to use at least one selected from the group consisting of alanine, arginine, glycine, cysteine, serine, and ectoin.

[0026] Furthermore, the above-mentioned component C is not particularly limited as long as the desired effect is achieved, whether as a single raw material or a mixed raw material with other components. In the present invention, the above-mentioned component C can be a commercially available product. Examples of commercially available alanine products include L-Alanine Kyowa (product name, manufactured by KH Neochem Co., Ltd.), examples of commercially available arginine products include L-Arginine C Grade (product name, manufactured by Ajinomoto Co., Ltd.), examples of commercially available glycine products include Glycine M (product name, manufactured by Fuso Chemical Industry Co., Ltd.), and examples of commercially available cysteine ​​products include L-Cysteine ​​(P) (product name, manufactured by Nippon Protein Co., Ltd.). Examples of commercially available serine products include L-Serine (product name, manufactured by Nippon Rikagaku Yakuhin Co., Ltd.), L-Serine (product name, manufactured by Junsei Kagaku Co., Ltd.), and PPAA-C (product name, manufactured by Seiwa Kasei Co., Ltd.). Examples of commercially available ectoin include RonaCare Ection, RonaCare Cyclopeptide-5 (trade names, both manufactured by Merck), and Ectoin natural (trade name, manufactured by Bitop AG).

[0027] The content of component C in the skin composition of the present invention is not particularly limited as long as the desired effect is sufficiently achieved. However, from the viewpoint of reducing the excessive stickiness caused by component A, it is generally preferable that the content be 0.01% by mass or more, and more preferably 0.1% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of usability, it is preferable that the content be 1.0% by mass or less, and more preferably 0.5% by mass or less, per 100% by mass of the composition. Note that the content of component C is the amount converted to pure content.

[0028] In the present invention, from the viewpoint of significantly reducing the excessive stickiness after application caused by component A, the ratio of the content of component C to component A (component C / component A) is preferably prepared to satisfy the range of 0.01 to 20.0, more preferably to satisfy the range of 0.05 to 5.0, and even more preferably to satisfy the range of 0.1 to 1.0.

[0029] [Component D] From the viewpoint of further enhancing the effect of reducing the raw material odor of component A, it is preferable that the skin composition of the present invention contains a polyglycerin fatty acid ester type nonionic surfactant as component D.

[0030] The number of carbon atoms in the fatty acids constituting the polyglycerin fatty acid ester of component D is not particularly limited, but is preferably 8 to 24, more preferably 10 to 20, and even more preferably 12 to 18. Furthermore, the fatty acid portion is not particularly limited as long as the desired effect is sufficiently exhibited, whether it is a saturated fatty acid or an unsaturated fatty acid, but from the viewpoint of further enhancing the raw material odor reduction effect of component A, it is preferable that it be an unsaturated fatty acid. On the other hand, the average degree of polymerization of the polyglycerin constituting the polyglycerin fatty acid ester is not particularly limited, but is preferably 2 to 12, and more preferably 5 to 10.

[0031] Examples of polyglycerol fatty acid esters of component D include monoesters, diesters, and triesters. Specifically, component D may include polyglycerol fatty acid monoesters, polyglycerol fatty acid diesters, and polyglycerol fatty acid triesters. Component D may also be a mixture of these.

[0032] Examples of the above-mentioned component D that can be used include hexaglyceryl monomyristate, decaglyceryl monostearate, decaglyceryl monoisostearate, decaglyceryl monooleate, decaglyceryl monolinoleate, decaglyceryl monocaprate, decaglyceryl monolaurate, decaglyceryl monomyristate, decaglyceryl dioleate, decaglyceryl distearate, decaglyceryl diisostearate, pentaglyceryl monolaurate, pentaglyceryl dioleate, hexaglyceryl monocaprylate, triglyceryl monocaprylate, poly(4-10)glyceryl monolaurate, poly(2-10)glyceryl monostearate, poly(2-10)glyceryl diisostearate, and poly(2-10)glyceryl monooleate. These components D may be used individually or in combination of two or more as appropriate.

[0033] Among the above components D, it is preferable to use decaglyceryl monooleate, decaglyceryl monostearate, decaglyceryl diisostearate, decaglyceryl monolinoleate, decaglyceryl dioleate, pentaglyceryl dioleate, and poly(2-10)glyceryl monooleate, and more preferably decaglyceryl monooleate, decaglyceryl monostearate, and decaglyceryl diisostearate.

[0034] Furthermore, component D is not particularly limited as long as the desired effect is achieved, whether as a single raw material or a mixed raw material with other components. In the present invention, commercially available products can be used for component D. Examples of commercially available products of decaglyceryl monooleate include Decaglyn 1-OV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.) and Sunsoft Q-17Y-C (trade name, manufactured by Taiyo Kagaku Co., Ltd.). Examples of commercially available products of decaglyceryl monostearate include Decaglyn 1-SV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.) and Sunsoft Q-18Y-C (trade name, manufactured by Taiyo Kagaku Co., Ltd.). Examples of commercially available products of decaglyceryl diisostearate include NIKKOL Decaglyn 2-ISV (trade name, manufactured by Nippon Surfactant Industry Co., Ltd.).

[0035] The content of component D in the skin composition of the present invention is not particularly limited as long as the desired effect is sufficiently achieved. However, from the viewpoint of further enhancing the raw material odor reduction effect of component A, it is generally preferable that the content be 0.1% by mass or more, and more preferably 0.2% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of usability, it is preferable that the content be 2.0% by mass or less, and more preferably 1.2% by mass or less, per 100% by mass of the composition. Note that the content of component D is the amount converted to pure content.

[0036] The skin composition of the present invention preferably contains a thickening polymer in order to maximize the effect of reducing the raw material odor and the effect of reducing stickiness after application by component A, and to further enhance the stability of the formulation. Examples of thickening polymers include water-soluble natural polymers, semi-synthetic polymers, and synthetic polymers. In this specification, the thickening polymer may be referred to as component E.

[0037] Examples of component E include natural polymers such as gum arabic, tragacanth gum, guar gum, locust bean gum, karaya gum, xanthan gum, iris moss, quince seed, gelatin, shellac, rosin, and casein; semi-synthetic polymers such as sodium carboxymethylcellulose, hydroxyethylcellulose, methylcellulose, ethylcellulose, sodium alginate, ester gum, nitrocellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, and crystalline cellulose; and synthetic polymers such as polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, (acrylates / alkyl acrylate (C10-30)) crosspolymer (acrylate / alkyl methacrylate copolymer), polyvinyl methylcellulose, and polyamide resin. These components E may be used individually or in appropriate combinations of two or more types.

[0038] The content of component E in the skin composition of the present invention is not particularly limited, but from the viewpoint of further improving formulation stability, it is preferably 0.01% by mass or more, and more preferably 0.1% by mass or more, per 100% by mass of the composition. Furthermore, from the viewpoint of usability, it is preferably 1.0% by mass or less, and more preferably 0.5% by mass or less, per 100% by mass of the composition. Note that the above content of component E is the amount converted to pure content.

[0039] [Other ingredients] In addition to the components described above, the skin composition of the present invention may contain, as long as it does not impair the effects of the present invention, oils other than component B, such as oils and fats, waxes, hydrocarbon oils, saturated fatty acids, higher alcohols, fatty acid ester oils, and silicone oils; surfactants other than component D, such as anionic surfactants, cationic surfactants, amphoteric surfactants, and nonionic surfactants; and film-forming agents, UV absorbers, whitening agents, anti-inflammatory agents, cooling agents, pH adjusters, neutralizing agents, fragrances, etc., as appropriate depending on the purpose.

[0040] The remainder of the skin composition of the present invention is purified water. The amount of purified water is not particularly limited, but from the viewpoint of exhibiting the effects of the present invention, it is preferably 30 to 95% by mass, and more preferably 50 to 90% by mass.

[0041] The method for producing the skin composition of the present invention is not particularly limited, but can be produced by known methods, for example. Specifically, the above components may be mixed and stirred using known methods, such as a disper mixer or disper mill, or emulsified by a phase inversion emulsification method using a homomixer, but the present invention is not limited to these production methods.

[0042] The use of the skin composition according to one embodiment of the present invention is not particularly limited, but it is preferably used as a skin cosmetic, and more specifically, it is preferably used as a moisturizing cosmetic, a whitening cosmetic, an acne care cosmetic, or an anti-aging cosmetic for purposes such as wrinkle suppression and sagging suppression. Furthermore, the skin composition of the present invention may take the form of cosmetics, quasi-drugs, designated quasi-drugs, general merchandise, etc.

[0043] Furthermore, the areas to which the skin composition according to one embodiment of the present invention is applied are not particularly limited, but as an example, it can be used on the face (forehead, around the eyes, corners of the eyes, cheeks, around the mouth, etc.), arms, elbows, back of the hands, fingertips, feet, knees, heels, neck, décolleté, armpits, back, etc. [Examples]

[0044] The present invention will be described in more detail below based on examples, but the present invention is not limited to these examples. Unless otherwise specified, the amounts of each ingredient are expressed in "mass%".

[0045] (Sample preparation 1) According to the compositions listed in Tables 1 and 2, the skin compositions of Examples 1-8 and Comparative Examples 1-5 were prepared into emulsifier forms according to conventional methods and subjected to the following evaluation. The results are shown in Tables 1 and 2. Note that all amounts in the tables are converted to pure content.

[0046] (Test Example 1: Evaluation of the presence or absence of raw material odor) Each sample from the examples and comparative examples was sealed in a 50 mL transparent glass container and stored in a 25°C constant temperature bath for 4 weeks. After storage, 1 g of each sample was applied to the back of the hand, and the presence or absence of a raw material odor caused by component A was evaluated by sensory assessment based on the odor released when spread. The evaluation was conducted by 10 expert panelists, and the judgment was made based on whether or not they could detect the raw material odor of component A, which they had smelled before the evaluation. Comparative Example 1, which does not contain component A, was not used in this test.

[0047] <Evaluation criteria for the presence or absence of raw material odor> ◎ (Very Good): 9-10 out of 10 people reported not noticing any raw material odor caused by ingredient A. ○ (Good): 6 to 8 out of 10 people reported not noticing any raw material odor caused by component A. △ (Insufficient): Out of 10 people, 3 to 5 responded that they did not detect any raw material odor caused by component A. × (Poor): Out of 10 people, 1-2 reported not detecting any raw material odor caused by ingredient A.

[0048] (Test example 2: Evaluation of stickiness after application) One g of each sample from the examples and comparative examples was placed in the palm of the hand and applied to both cheeks. Thirty minutes after application, a sensory evaluation was conducted on the "stickiness" of the applied area, and the result was determined according to the evaluation criteria below. The evaluation was conducted under conditions of 25°C by 10 expert evaluators, and the final result was determined by combining the evaluations of each evaluator.

[0049] <Evaluation criteria for stickiness after application> ◎ (Very good): No stickiness at all, providing an optimal user experience. ○ (Good): There is a very slight stickiness, but the overall user experience is good. △ (Insufficient): It feels slightly sticky and cannot be said to have a good user experience. × (Defective): Clearly sticky and poor usability.

[0050] [Table 1]

[0051] [Table 2]

[0052] The results shown in Tables 1 and 2 show that, compared to the comparative examples, the skin compositions obtained in each example significantly suppressed the raw material odor caused by coenzyme Q10, despite containing a high concentration of coenzyme Q10, and also significantly reduced the sticky feeling after application. On the other hand, comparative examples 1 to 3, which did not satisfy the essential components of the present invention, and comparative examples 4 to 5, which were replaced with other components, did not fully demonstrate the effects of the present invention.

[0053] As is clear from these results, the skin composition of the present invention can solve both the raw material odor and stickiness issues that have been difficult to address in conventional attempts with compositions containing a high concentration of coenzyme Q10.

Claims

1. It contains the following components A, B, C, and D: A skin composition characterized in that the content of component A is more than 0.3% by mass and 1.0% by mass or less. Component A: Coenzyme Q10 Ingredient B: Unsaturated fatty acid ester oil Ingredient C: Amino Acids Ingredient D: Polyglycerin fatty acid ester type nonionic surfactant

2. The skin composition according to claim 1, wherein component C is at least one selected from the group consisting of alanine, arginine, glycine, cysteine, serine, and ectoin.

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