Hair treatment composition and method

Abstract

A personal cleansing composition comprising: i) a piroctone compound; ii) a cleansing surfactant comprising an amphoteric surfactant and an ethoxylated alkyl sulfate surfactant, wherein the weight ratio of the ethoxylated alkyl sulfate to the amphoteric surfactant is 2:1 to 6:1; and iii) a cationic polymer comprising polyquaternium 6.

Description

[Technical Field]

[0001] This invention relates to a hair treatment composition, and more particularly to an anti-dandruff shampoo composition. [Background technology]

[0002] Dandruff is a problem that affects many parts of the world. This condition manifests as clumps of dead skin cells shedding from the scalp, which are white in color and give an aesthetically unpleasant appearance. One factor contributing to dandruff is certain members of the Malassezia yeast. To combat these yeasts, hair treatment compositions containing various active substances for dandruff prevention have been developed. Piroctone compounds, such as piroctone olamine, are one such active substance.

[0003] A common problem with piroctone compounds is minimizing the deposition of the active substance onto the desired surface during the cleansing process. The desired surface is typically the scalp and / or hair. For example, piroctone compounds such as piroctone olamine are usually soluble in the surfactants of the cleansing phase in hair treatment compositions. During excessive rinsing, most of the piroctone is easily washed away along with the surfactant. Insufficient deposition correlates with low anti-dandruff activity, resulting in little mitigation of the adverse effects of dandruff. To date, attempts have been made to counteract this drawback by increasing the level of piroctone olamine in hair treatment compositions. Such methods introduce various problems, including increased costs, potential instability of the formulation, and potential adverse effects on hair feel. Therefore, it is not a preferred method in the industry.

[0004] German Patent No. 102012203240 describes a hair treatment composition that enhances dandruff prevention and improves hair combability, shine, and elasticity. The composition comprises an anti-dandruff agent selected from zinc pyrithione, crimbazole, octopirox, ketoconazole, selenium disulfide, selenium-containing vegetable oil, selenium-containing vegetable extract, and cationic aminosilicone. Examples include shampoos and conditioners containing Octopirox® (piroctone olamine), aminosilicone, and surfactants.

[0005] U.S. Patent No. 2013 / 0059929 describes a cosmetic or dermatological preparation comprising at least one of benzethonium chloride, methylisothiazolinone, piroctone olamine, and lauroyl ethyl alginate, and free from preservatives containing phenol groups. The preparation exhibits improved sensory properties and sufficient microbiological stability.

[0006] U.S. Patent No. 2002 / 0035161 describes a cosmetic / medical oil-in-water emulsion comprising a discontinuous fatty phase dispersed in a continuous aqueous phase, an effective amount of at least one biologically active substance (A), and an effect amount of an emulsifying system (B), wherein the at least one biologically active substance (A) is insolubilized therein in the form of fine particles, and numerically at least 80% of the fine particles have a diameter in the range of 1 to 10 μm, and numerically at least 50% have a diameter of less than 5 μm.

[0007] Despite all prior art, there remains a need to improve the deposition of piroctone compounds, particularly piroctonic acids or piroctone olamines, on the surface of the scalp and / or hair during the cleansing process. Furthermore, there is still a need to improve this deposition without adverse side effects on sensory perception, formulation rheology, and conditioning performance. [Prior art documents] [Patent Documents]

[0008] [Patent Document 1] German Patent No. 102012203240 [Patent Document 2] U.S. Patent No. 2013 / 0059929 [Patent Document 3] U.S. Patent No. 2002 / 0035161 [Overview of the Initiative]

[0009] The present invention The present invention relates to a personal cleansing composition according to claim 1, and to a non-therapeutic method for treating hair or scalp according to claim 11.

[0010] The above compositions for use in the treatment of hair or scalp are further described.

[0011] To avoid doubt, any feature of one aspect of the present invention may be utilized in any other aspect of the present invention. Any feature described as “preferred” should be understood as particularly preferred in combination with one or more more preferred features. In this specification, any feature of a particular embodiment may be utilized in any other aspect of the present invention. The examples given in the following description are intended to clarify the present invention, but not to limit it. All percentages are weight / weight % unless otherwise indicated. [Modes for carrying out the invention]

[0012] Piroctone compounds for use in the present invention include piroctonic acid, primary, secondary, and tertiary olamine salts of piroctonic acid (such as diethanolamine salts and triethanolamine salts), and mixtures thereof, preferably piroctonic acid, primary olamine salts of piroctonic acid (i.e., piroctone olamine, also known as Octopirox®), and mixtures thereof.

[0013] Piroctone olamine is the olamine salt of the hydroxamic acid derivative piroctone. It is generally known as piroctone ethanolamine under the trade name Octopirox (registered trademark).

[0014] The piroctone olamine according to the present invention is a 1:1 compound of 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone and 2-aminoethanol, and is also called 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)pyridinone monoethanolamine salt. The CAS number is 68890-66-4, and the compound has the following general formula (I):

Chemical formula

[0015] The piroctone compound, particularly piroctone olamine, is preferably present at 0.01 to 5% by weight, more preferably 0.1 to 5% by weight, and most preferably 0.2 to 3% by weight of the total composition.

[0016] The cosmetic composition contains one cleansing surfactant. A surfactant is a compound having a hydrophilic part and a hydrophobic part that acts to lower the surface tension of an aqueous solution in which they are dissolved. The cleansing surfactant includes an amphoteric surfactant and an ethoxylated anionic surfactant, and the anionic surfactant preferably has an average ethoxylation degree of 2 or more, more preferably 2.5 or more, and most preferably 3 or more.

[0017] The alkyl chain of the ethoxylated anionic surfactant preferably has 8 to 18, more preferably 10 to 16 carbon atoms and may be unsaturated. Preferred alkyl ether sulfates are those of the following formula (I): R-O-(CH2CH2-O)

[0018] , , - , ,

[0016] , , + , , , n ,

[0017] , -SO3 - M + (I)

[0018] In the formula, R is a linear or branched alkyl chain having 8 to 18 (preferably 12 to 18) carbon atoms, n is an average ethoxylation degree of 2 or more, more preferably 2.5 or more, and most preferably 3 or more, (M is a solubilizing cation such as sodium, potassium, ammonium or substituted ammonium. An example is sodium lauryl ether sulfate (SLES). The most preferred example is SLES having an average ethoxylation degree of 3 or more, preferably 3, and preferably the surfactant is sodium laureth sulfate (3EO).

[0019] Preferred amphoteric or zwitterionic cleansing surfactants include alkylamine oxides, alkyl betaines, alkylamidopropyl betaines, alkyl sulfobetaines (sultaines), alkyl glycinates, alkyl carboxyglycinates, alkyl amphoacetates, alkyl amphopropionates, alkyl amphoglycinates, alkylamidopropyl hydroxysultaines, acyl taurates, and acyl glutamates, where the alkyl and acyl groups have 8 to 19 carbon atoms. Preferred amphoteric surfactants include cocodimethylsulfopropyl betaine, lauryl betaine, cocobetaine, cocamidopropyl betaine, and sodium cocoamphoacetate. A particularly preferred amphoteric surfactant is cocamidopropyl betaine.

[0020] Preferably, the ratio of the ethoxylated anionic surfactant to the amphoteric surfactant is 2:1 to 6:1, and more preferably 3:1 to 4:1.

[0021] The total amount of cleansing surfactant in the shampoo composition for use in the present invention is generally 3-20%, preferably 5-15%, and more preferably 6-12%, based on the total weight of the composition, in terms of total weight surfactant. 。

[0022] Non-limiting examples of additional cleansing surfactants include aliphatic (C8-C 18 ) primary or secondary linear or branched alcohols having alkylene oxide, usually ethylene oxide, and generally having 6 to 30 ethylene oxide groups. However, it is preferred that no nonionic cleansing surfactant is present. Other representative cleansing surfactants include mono- or di-alkyl alkanolamides (examples include coco mono-ethanolamide and coco mono-isopropanolamide) and alkyl polyglycosides (APG). Alkyl polyglycosides suitable for use in the present invention are commercially available and include materials specified, for example, as Plantapon 1200 and Plantapon 2000 manufactured by BASF. Other sugar-derived surfactants that may be included in the composition for use in the present invention include, for example, C 12 -C 18 N-methylglucamide and the like, and C 10 -C 18 N-alkyl (C1-C6) polyhydroxy fatty acid amides, as well as C 10 -C 18 N-(3-methoxypropyl) glucamide and the like of N-alkoxy polyhydroxy fatty acid amides.

[0023] Mixtures of any of the aforementioned anionic, nonionic and amphoteric cleansing surfactants may also be suitable, and preferably, the ratio of the first surfactant to the second surfactant is 1:1 to 10:1, more preferably 2:1 to 9:1, and most preferably 3:1 to 8:1 based on the weight content of the cleansing surfactant in the shampoo composition.

[0024] The personal care composition may contain at least one cationic deposition polymer.

[0025] The cationic polymer contains a dimethyldiallylammonium moiety

[0026] Preferred cationic polymers are homopolymers or copolymers in which the dimethyldiallylammonium moiety is one of the monomers. More preferred cationic polymers are polyquaternium-6, polyquaternium-7, and polyquaternium-22. Particularly preferred is polyquaternium-6.

[0027] Typically, the cationic polymer is present at a level of 0.01 to 5% by weight, preferably 0.05 to 2% by weight, and more preferably 0.1 to 1% by weight of the whole composition.

[0028] Additional cationic deposition polymers may be included, but these are undesirable.

[0029] Other cationic polymers include polygalactomannan and polysaccharide polymers, such as cationic cellulose derivatives and cationic starch derivatives.

[0030] A mixture of any of the above cationic polymers may be used.

[0031] Preferably, the compositions of the present invention, and in particular the aqueous shampoo compositions for use in the present invention, further comprise a suspending agent. Suitable suspending agents are selected from polyacrylic acid, crosslinked polymers of acrylic acid, copolymers of acrylic acid and hydrophobic monomers, copolymers of carboxylic acid-containing monomers and acrylic acid esters, crosslinked copolymers of acrylic acid and acrylate esters, heteropolysaccharide gums, and crystalline long-chain acyl derivatives. The long-chain acyl derivatives are preferably selected from ethylene glycol stearate, alkanolamides of fatty acids having 16 to 22 carbon atoms, and mixtures thereof. Ethylene glycol distearate and polyethylene glycol 3-distearate are preferred long-chain acyl derivatives because they impart a pearlescent luster to the composition. Polyacrylic acid is commercially available as Carbopol 420, Carbopol 488, or Carbopol 493. Polymers of acrylic acid crosslinked with polyfunctional agents may also be used. These are commercially available as Carbopol 910, Carbopol 934, Carbopol 941, and Carbopol 980. A suitable copolymer of a carboxylic acid-containing monomer and an acrylic acid ester is Carbopol 1342. All Carbopol® materials are available from Goodrich.

[0032] The suspension is generally present in the shampoo composition for use in the present invention at a level of 0.1 to 10%, preferably 0.15 to 6%, and more preferably 0.2 to 4%, based on the total weight of the composition.

[0033] A cosmetic composition may contain one or more components, provided that any component is physically and chemically compatible with the aforementioned essential components and does not otherwise excessively impair the sensory properties, formulation rheology, and conditioning performance. The individual concentration of any such component may range from 0.001% to 10% by weight, preferably 0.01% to 5% by weight, of the whole composition. Such components may include conditioning agents, fragrances, dyes, pigments, pH adjusters, pearlescent or opaque agents, viscosity modifiers, preservatives, and natural hair nutrients such as plant components, fruit extracts, sugar derivatives, and amino acids.

[0034] One of the preferred components is a suspending agent. Preferred suspending agents are selected from polyacrylic acid, crosslinked polymers of acrylic acid, copolymers of acrylic acid with hydrophobic monomers, copolymers of carboxylic acid-containing monomers with acrylic acid esters, crosslinked copolymers of acrylic acid with acrylate esters, heteropolysaccharide gums, and crystalline long-chain acyl derivatives. The long-chain acyl derivatives are preferably selected from ethylene glycol stearate, alkanolamides of fatty acids having 16 to 22 carbon atoms, and mixtures thereof. Ethylene glycol distearate and polyethylene glycol 3-distearate are preferred long-chain acyl derivatives because they impart a pearly luster to the composition. Polyacrylic acid is commercially available as Carbopol 420, Carbopol 488, or Carbopol 493. Polymers of acrylic acid crosslinked with polyfunctional agents may also be used. These are commercially available as Carbopol 910, Carbopol 934, Carbopol 941, and Carbopol 980. A suitable copolymer of carboxylic acid-containing monomers and acrylic acid esters is Carbopol 1342. All Carbopol® materials are available from Goodrich. Suitable crosslinking polymers of acrylic acid and acrylate esters are Pemuren TR1 or Pemuren TR2. Suitable heteropolysaccharide gums are xanthan gums, available as, for example, Kelzan mu.

[0035] A mixture of any of the above suspensions may be used. A mixture of acrylic acid and a crosslinked polymer of a crystalline long-chain acyl derivative is preferred.

[0036] The most preferred example is a cross-linked polyacrylate polymer.

[0037] If present, the suspending agent is generally present in the composition at a level of 0.01 to 5% by weight, preferably 0.1 to 2.5% by weight, and more preferably 0.25 to 1% by weight.

[0038] Another preferred optional component is a conditioning agent that provides a conditioning effect. Typically, the most common conditioning agents used in cosmetic compositions are water-insoluble oily materials such as mineral oil, and naturally occurring oils such as triglycerides and silicone polymers. The conditioning effect is achieved by the oily material depositing on the hair to form a film, which makes the hair smoother and less prone to dryness. Preferably, the conditioning agent is non-volatile, meaning it has a vapor pressure of less than 1000 Pa at 25°C.

[0039] Preferably, the composition has an average droplet diameter (D) of less than 50 microns, preferably less than 30 microns, more preferably less than 15 microns, and most preferably less than 10 microns. 3,2 It contains separated dispersion droplets of a water-insoluble conditioning agent having ). The average droplet diameter (D) of the water-insoluble conditioning agent. 3,2 ) can be measured by laser light scattering techniques, for example, using a 2600D Particle Sizer from Malvern Instruments.

[0040] Water-insoluble conditioning agents may include non-silicone conditioning agents containing non-silicone oily or fatty materials such as hydrocarbon oils, fatty esters, and mixtures thereof. Preferably, the water-insoluble conditioning agent is an emulsified silicone oil.

[0041] Suitable silicones include polydiorganosiloxanes, particularly polydimethylsiloxanes having the CTFA designation dimethicone. Also suitable for use in the compositions of the present invention (especially shampoos and conditioners) are polydimethylsiloxanes having hydroxyl-terminated groups and the CTFA designation dimethiconol. Low-crosslinking silicone gums are also suitable for use in the compositions of the present invention, for example, as described in International Publication No. 96 / 31188. Preferably, the silicone oil contains dimethicone, dimethiconol, or a mixture thereof.

[0042] The viscosity of the emulsifying silicone itself (not the emulsion or final hair care composition) is typically at least 10,000 cSt (centistokes = mm) at 25°C. 2 ·S -1 ), preferably at least 60,000 cSt, most preferably at least 500,000 cSt, and ideally at least 1,000,000 cSt. Preferably, the viscosity is 10 to facilitate formulation. 9 The cSt should not exceed the specified value. A suitable method for measuring the kinematic viscosity of silicone oil is known to those skilled in the art, for example, a capillary viscometer. In the case of high-viscosity silicones, the viscosity can be measured using a constant-stress rheometer.

[0043] Emulsified silicones suitable for use in compositions are available as pre-formed silicone emulsions from silicone suppliers, such as Dow Corning and GE Silicones. The use of such pre-formed silicone emulsions is preferred to facilitate the processing and control of silicone particle size. Such pre-formed silicone emulsions typically further contain a suitable emulsifier and can be prepared by chemical emulsification processes such as emulsion polymerization, or by mechanical emulsification using a high-shear mixer.

[0044] Suitable examples of pre-formed silicone emulsions include DC1785, DC1788, and DC7128, all available from Dow Corning. These are dimethiconol / dimethicone emulsions.

[0045] Another class of silicones that can be used is functionalized silicone, such as amino-functional silicone, which means a silicone containing at least one primary, secondary, or tertiary amine group or a quaternary ammonium group. A suitable example of an amino-functional silicone is a polysiloxane having the CTFA name "amodimethicone".

[0046] Preferably, the silicone emulsion droplets are blended with a high molecular weight of a particular type of surface-active block polymer to form a silicone emulsion, as described, for example, in International Publication No. 03 / 094874. One preferred form of the surface-active block polymer having polyoxypropylene and polyoxyethylene groups as hydrophobic and hydrophilic moieties, respectively, is the CTFA-named poloxamer, which has formula V and is commercially known under the trade name "Pluronic" by BASF. V)HO(CH2CH2O) x (CH(CH3)CH2O) y (CH2CH2O) x H

[0047] Preferably, the average value of x in formula I is 4 or greater, preferably 8 or greater, more preferably 25 or greater, even more preferably 50 or greater, and most preferably 80 or greater. The average value of x is typically 200 or less. Preferably, the average value of y is 25 or greater, preferably 35 or greater, more preferably 45 or greater, and most preferably 60 or greater. The average value of y is typically 100 or less.

[0048] Another preferred form of the surface-active block polymer is that of formula VI, having the CTFA name poloxamine. These are commercially available from BASF under the trade name "Tetronic". VI)(HO(CH2CH2O) a (CH(CH3)CH2O) b )2-N-CH2-CH2-N-((OCH2CH(CH3)) b (OCH2CH2) a OH)2

[0049] Preferably, the average value of a is 2 or more, preferably 4 or more, more preferably 8 or more, even more preferably 25 or more, and most preferably 40 or more. The average value of a is typically 200 or less. The average value of b is preferably 6 or more, preferably 9 or more, more preferably 11 or more, and most preferably 15 or more. The average value of b is typically 50 or less.

[0050] Preferably, the surface-active block polymer is poloxamer and / or poloxamine, and more preferably, the surface-active block polymer is poloxamer.

[0051] Preferably, the surface-active block polymer is blended with dimethicone. The weight ratio of dimethicone to the surface-active block polymer in the blend is preferably in the range of 2:1 to 200:1, more preferably 5:1 to 50:1, even more preferably 10:1 to 40:1, and most preferably 15:1 to 30:1.

[0052] Water-insoluble conditioning agents are generally present in the composition in amounts of 0.05 to 15%, preferably 0.1 to 10%, more preferably 0.5 to 8%, and most preferably 1 to 5%, based on the total weight of the composition, including all the ranges encompassed therein.

[0053] The composition may preferably contain a pearlescent agent. A preferred pearlescent agent is an ethylene glycol ester disclosed in U.S. Patent No. 4,885,107, which is incorporated herein by reference. Preferably, the ethylene glycol ester is a mono- or di-ester of glycol, and more preferably a di-ester of glycol.

[0054] Preferably, the ethylene glycol mono- or di-ester is C 12 ~ 22 Ethylene glycol mono- or di-esters of fatty acids, more preferably saturated C 12 ~ 22 The pearlescent agent is an ethylene glycol mono- or di-ester of a fatty acid. Diesters containing a mixture of palmitate and stearate are most preferred. The amount of stearate should be in the range of about 10% to about 42%, or about 55% to about 80%, with palmitate making up the remainder. The amount of stearate is preferably about 60% to about 75%, more preferably about 80% to 95%, and most preferably 100%. The most preferred example of a pearlescent agent is ethylene glycol distearate. The pearlescent agent can also function as a suspending agent.

[0055] The level of ethylene glycol ester may preferably be about 0.5% to about 6% by weight of the total composition, and more preferably about 1% to about 4% by weight.

[0056] The viscosity of the composition is preferably in the range of 3,000 to 10,000 mPa.s, more preferably 4,000 to 8,000 mPa.s, and more preferably 5,000 to 7,000 mPa.s, when measured using a Brookfield V2 viscometer (spindle RTV5, 1 min, 20 rpm) at 30°C.

[0057] The pH of the composition of the present invention is preferably in the range of 3 to 9, more preferably 4 to 8, and most preferably 4.5 to 6.5.

[0058] Rinse-off compositions are intended to be rinsed off the user's scalp with water after use. Rinse-off compositions are preferred. Leave-on compositions are intended not to be rinsed off the user's scalp immediately after use (i.e., within at least the first two hours, preferably at least four hours, after application of the composition). In the context of the present invention, rinse-off compositions include shampoos and conditioners, as well as treatment compositions that may be left on the scalp for 0.5 minutes to a maximum of 15 minutes, preferably 1 to 10 minutes, and more preferably 1 to 10 minutes, before rinsing.

[0059] A preferred use of the cosmetic composition is in shampoos, particularly rinse-off shampoos. The shampoo compositions for use in the present invention are generally aqueous; that is, they have water or an aqueous solution or a lyotropic liquid crystal phase as their main component. Preferably, the shampoo composition contains 50-98% by weight, preferably 60-92% by weight, of water based on the total weight of the composition. Such compositions are referred to as having an aqueous base.

[0060] The present invention will now be described by the following non-limiting embodiments.

[0061] [Examples] The compositions were prepared according to Table 1.

[0062] [Table 1]

[0063] Piroctone olamine deposition was measured by thoroughly wetting 10 clean dark brown European hairpieces with water (2.5g / 6''). Five replicas were tested for each shampoo composition. 0.25g of shampoo was applied to one hairpiece and massaged for 30 seconds. The hairpiece was then rinsed with water for 30 seconds. Another 0.25g of shampoo was applied and massaged for another 30 seconds. The shampoo was then rinsed off with water for 30 seconds. The hairpieces were allowed to air dry. The dried hairpieces were extracted in 50ml of ethanol. Care was taken to avoid exposing the extracts to UV light. The extracts were analyzed for piroctone acid deposition by UPLC. The results are shown in Table 2.

[0064] [Table 2]

[0065] The results in Table 2 demonstrate that the examples of the present invention are more effective than the comparative examples in depositing piroctone olamine.

Claims

1. i) Piroctone compounds selected from piroctonic acids, primary, secondary and tertiary olamine salts of piroctonic acids, and mixtures thereof, ii) A cleansing surfactant comprising an amphoteric surfactant and an anionic surfactant, wherein the anionic surfactant is an ethoxylated alkyl sulfate surfactant, and the weight ratio of the ethoxylated alkyl sulfate to the amphoteric surfactant is 2:1 to 6:1, iii) Cationic polymers containing polyquaternium-6 A personal cleansing composition comprising: The aforementioned amphoteric surfactant is selected from the group consisting of cocodimethylsulfopropyl betaine, lauryl betaine, cocobetaine, cocamidopropyl betaine, and sodium cocoamphoacetate. A personal cleansing composition wherein the anionic surfactant has an average degree of ethoxylation of 2 or more.

2. The personal cleansing composition according to claim 1, wherein the piroctone compound is a diethanolamine salt or triethanolamine salt of piroctonic acid.

3. The personal cleansing composition according to claim 1 or 2, wherein the weight ratio of ethoxylated alkyl sulfate to amphoteric surfactant is 3:1 to 4:

1.

4. A personal cleansing composition according to any one of claims 1 to 3, wherein the total amount of cleansing surfactants is less than 11% by weight of the entire composition.

5. The personal cleansing composition according to claim 4, wherein the total amount of cleansing surfactants is 10% by weight of the entire composition.

6. The personal cleansing composition according to any one of claims 1 to 5, wherein the amphoteric surfactant is cocamidopropyl betaine.

7. The personal cleansing composition according to any one of claims 1 to 6, wherein the anionic surfactant has an average degree of ethoxylation of 2.5 or more.

8. The personal cleansing composition according to any one of claims 1 to 6, wherein the anionic surfactant has an average degree of ethoxylation of 3 or more.

9. The personal cleansing composition according to any one of claims 1 to 8, wherein the ethoxylated alkyl sulfate is sodium laureth sulfate (3EO).

10. The personal cleansing composition according to any one of claims 1 to 9, wherein the piroctone compound is piroctone olamine.

11. A personal cleansing composition according to any one of claims 1 to 10, further comprising silicone.

12. A personal cleansing composition according to any one of claims 1 to 11, comprising a piroctone compound in a total amount of 0.1 to 5% by weight of the whole composition.

13. The personal cleansing composition according to claim 12, comprising a piroctone compound in a total amount of 0.2 to 3% by weight of the entire composition.

14. A personal cleansing composition according to any one of claims 1 to 13, which is a shampoo.

15. A non-therapeutic method for treating hair or scalp, comprising applying a personal cleansing composition according to any one of claims 1 to 14 to the hair or scalp.

16. The non-therapeutic method according to claim 15, wherein the composition is washed away after use.

17. A personal cleansing composition according to any one of claims 1 to 14, for use in treating hair or scalp.

18. A personal cleansing composition according to any one of claims 1 to 14, for use in reducing dandruff.

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