Stable synergistic herbicidal composition

Abstract

The present invention relates to a synergistic herbicidal composition for broad spectrum weed control in all stages of weed growth.

Description

[0001] “STABLE SYNERGISTIC HERBICIDAL COMPOSITION”

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to a synergistic herbicidal composition for broad spectrum weed control in all stages of weed growth. More particularly, the present invention relates to a synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2- chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically knownas Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof for broad spectrum weed control in all stages of weed growth. The present invention also relates to process for preparing the said composition and its use as herbicide.

[0004] BACKGROUND OF THE INVENTION

[0005] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the present invention, or that any publication specifically or implicitly referenced is prior art.

[0006] Herbicides are pesticides useful for killing or controlling unwanted plants / weeds. The agriculture industry uses a wide range of herbicides, primarily to control undesired growth of weeds which interfere with growth, development, yield and quality of agricultural crops. They are used to provide an optimum environment for growth and propagation of plant varieties. Modern herbicides are used to either control or suppress these undesirable plants so as to allow sown crops a greater share of nutrient.

[0007] The control of undesired vegetation is extremely important in achieving high crop efficiency, yield and growth. Unchecked weed growth in useful crops can cause significant reduction in productivity and thereby result in increased costs to the consumer. The control of undesired vegetation in non-crop areas is also important.

[0008] Weeds are undesirable plants that can severely damage yield in crops. Farmers usually control these plants at the pre-plant stage as well as after sowing. The weeds can reduce field crop yields by competing for water, sunlight and nutrients. Profitable crop production depends on effective weed control.

[0009] So, there exists a continuous need to develop an herbicidal composition which is compatible and stable, synergistic, broad spectrum, environmentally safe and more effective in control of various types of weeds in crops in all stages of weed growth. Also, it is economically very important to control of weeds or unwanted for the crop productivity. Researchers in the field of synthetic chemistry have produced an extensive variety of chemicals and chemical formulations as solo or in combination of active ingredients for the control of such weeds or unwanted plants. Formulation of chemical herbicides of many types have been disclosed in the literature. In order to minimize the risk from increased number of herbicide resistant varieties of weeds, mixtures of different active compounds are nowadays employed for controlling weeds or unwanted plants as known in art. By combining different active compounds having different mechanisms of action, it is possible to ensure successful control of weeds over a relatively longer period of time and preventing development of resistance. But this requires continuous development of an effective composition with different active ingredients.

[0010] However, there still exists a scope for research and development of novel formulations, compositions for weed control, which are environmentally safe, cost-effective and which can be used for protection of crops during the critical periods of cultivation capable of acting both on the narrow-leaved and broad-leaved weeds, grasses and sedges and effective during all the stages of weed life cycle. The control of undesired vegetation is extremely important in achieving high crop efficiency. Achievement of selective control of the growth of weeds especially in such useful crops as rice, soybean, ground nut, cotton, sugar beet, corn (maize), potato, wheat, barley, tomato and plantation crops such as sugarcane, among others, is very desirable. Unchecked weed growth in such useful crops can cause significant reduction in productivity and thereby result in increased costs to the consumer. Many products are commercially available for these purposes, but the need continues for new products that are more effective, synergistic, less costly, less toxic, environmentally safer or have different modes of action and not resistant to weeds.

[0011] More so, a wide range of herbicide compositions contain only a single active ingredient and cannot contain two or more active ingredients due to several reasons like adverse reactions, non-synergistic effects, non-compatibility of intermixed ingredients etc. However, the combinations currently known are not sufficient to control the resistant and persistent weeds. Growers, increasingly face complex weed situations that may not be controlled with just one herbicide.

[0012] Further, a majority of the commercially available chemical herbicides are selective in their action. A common problem with selective herbicides is its weed control spectrum, meaning the range of weed species effectively controlled by the herbicide, does not cover the full diversity of weeds affecting the crop and are not broad spectrum in nature. It is therefore, a practice to apply two or more herbicides simultaneously in order to achieve maximum spectrum of control. But it requires a lot of human ingenuity and rigorous efforts to identify compatibility between the active ingredients and the specific ratios in which these components must be mixed so as to obtain the maximum desired results. However, a common problem with selective herbicides is its weed control spectrum, meaning the range of weed species effectively controlled by the herbicide, does not cover the full diversity of weeds affecting the crop and are not broad spectrum in nature.

[0013] Combinations of herbicides are used to control a broader range of weeds. However, the combination of herbicides may not always result in the desired effect. Combination of herbicides may lead to an additive effect or an antagonistic effect. It may also result in phytotoxicity to the crops making it an undesirable combination. Agronomists must therefore, carefully select the herbicides that can be combined to offer a synergistic effect that would control weeds while having no phytotoxic effect on the crop, and reduce the chances of development of herbicide resistant weeds. Thus, there still remains a need for improved herbicidal combinations that can effectively control weeds thereby improving yield and plant health, with reduced phytotoxicity and have synergistic effect in terms of weed control.

[0014] Also, it is always preferable to be able to reduce the amount of chemical agents released into the environment while still ensuring effective weed control. Combinations of herbicides are typically used to broaden the spectrum of weed control, to minimize the doses of chemicals used, and to retard resistance development. Although weed control agent combinations have been studied, a high synergistic action has not always been found. There is however a need for improvement of these combinations. Single active compositions used over a long period of time has resulted in resistance. With the onset of resistance to certain weeds, there is a need in the art for a combination of actives that decrease the chances of resistance against weeds. Herbicide performance is affected by numerous environmental factors, including sunlight, temperature, water stresses and quality.

[0015] Herbicidal compositions that can be applied at low dosage as possible and be effective in controlling weeds while causing as little harm as possible to the environment are in demand by the farming community. Weeds are very destructive to crops and can result in significant loss of crop yield and quality, which results in economic loss to the farmer and increased cost to the end user. Although, many combinations of herbicidal agents have been studied, a synergistic effect is rarely attained. Therefore, there is still a need for novel herbicidal composition comprising combination of herbicides which have different chemistry but are broad spectrum to cover efficacious control of large number of weeds, which also exhibits synergistically enhanced action, a broader scope of activity at a reduced cost of treatment.

[0016] Another common problem with many commercially available herbicides is the narrow window of application. Most of them provide either a pre-emergence or a post-emergence weeds control. An effective weed control can be achieved by usage of herbicides appropriately, which can be applied as an early post emergence to late post emergence. The activity of herbicides can be enhanced in various ways to achieve the maximum benefit. One of the ways is to use combinations. There is always a need in the art for improved herbicidal combinations with enhanced weed control efficacy, which are safe to crops and have no adverse effect on germination or growth of succeeding crops. Thus, there arises a need in the art to combine herbicides with varied modes of action, which allows for broader spectrum of control, targeted effect and good resistance management apart from good residual effect on succeeding crops using lower application rates.

[0017] Unfortunately, it is usually not possible to predict synergistic activity for combinations of known herbicides, even if the compounds show a close structural similarity to known synergistic combinations. Accordingly, it is desirable to develop compositions and processes comprising combination of herbicides having different mode of action to give improved herbicidal bio-efficacy, broad-spectrum activity with better weed control, increased crop yield and reduced weed resistance and better crop safety by having targeted action on weeds and minimum damage to succeeding crops.

[0018] There is a need for an herbicidal formulation that is highly efficient, non- toxic, covers a broader spectrum of weeds and is environment friendly and economical. So, there exists a continuous need for new herbicidal combinations to be applied so as to provide an economical and effective solution in terms of weed control, yield, plant growth, broader crop protection spectrum, which can possibly reduce the burden on the environment / farmers, healthy foliage, saves labour cost and is yet cost-effective to the end user.

[0019] There are various prior arts which disclose compositions comprising combination of herbicide actives. Some of such prior arts are listed below:

[0020] Reference can be made to CN102349527A, which discloses a haloxyfop-r-methyl-containing herbicide composition mixed synergistic active component B, wherein the herbicide mixed synergistic active component B is one or more of diphenyl ether herbicides, sulfonylurea herbicides or benzothiazine dione herbicides. The weight ratio of haloxyfop-r-methyl to the herbicide mixed synergistic active component B is (1 to 30%): (0.5 to 50%).

[0021] Reference can also be made to US20100273655 Al, which discloses a herbicidal composition comprising a blend of a) from about 0.3 to about 4 parts by volume of a herbicide formulation, said formulation containing an effective amount of at least one herbicidal agent; b) from about 5 to about 20 parts by volume of a modified plant oil; and c) from about 5 to about 20 parts by volume of a compostable organic particulate.

[0022] However, combining herbicidal actives shows compatibility issues among them and thus formulating a stable composition which provide efficacious synergistic results against weeds is a tedious task. And, it is always desired to provide an improved composition and convenient method which effectively control and eventually eliminate unwanted weedy species from the agricultural crops. So, there is a constant need for the development and application of synergistic formulations which are not only effective in weed control, but also help in increasing the yield of crop.

[0023] The efficacy and chemical stability of the active ingredients and physical stability of the formulated composition may be affected by inert ingredients in the formulation, suitable inert ingredients should not cause decomposition of the active ingredient. Furthermore, inert ingredients should be non-phytotoxic and environmentally safe. Inert ingredients of formulations intended for dilution with water before application should be easily dissolved or dispersed in water.

[0024] As a solution to the above mentioned problems, the inventors of the present invention surprisingly found that composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2- chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof, is synergistically effective for broad spectrum weed control in all stages of weed growth.

[0025] Aryloxy phenoxy propionate herbicides are mainly used for preventing and killing gramineous weeds, and are widely applied to crop fields all over the world due to high efficiency and low toxicity. Aryloxy phenoxy propionate compounds are important in acetyl coenzyme A carboxylase (ACCase) inhibitors, for efficiently preventing and removing gramineous weeds. The aryloxy phenoxy propionate herbicide has the advantages of broad spectrum, extremely low dosage and strong selectivity. Such herbicides inhibit acetyl-coa carboxylase, stop fatty acid synthesis, and destroy lipid-containing structures such as membrane systems, and finally cause plant death.

[0026] Haloxyfop belongs to the class of aryloxyphenoxypropionic acid having chemical name (7?S)- 2-(4-{ [3-chloro-5-(trifluoromethyl)-2-pyridyl]oxy}phenoxy)propionic acid. It is selectively absorbed by roots and foliage. It has an action mechanism of inhibiting the activity of acetyl CoA carboxylase. Chemical structure of Haloxyfop is provided below:

[0027]

[0028] Haloxyfop

[0029] Haloxyfop-R-Methyl: It is the most active enantiomer of the racemic herbicide haloxyfop. Chemical Name- Methyl (RS)-2-(4-{ [3-chloro-5-(trifluoromethyl)-2-pyridyl]oxy}phenoxy) propionic acid is an aryloxy phenoxy propionic acid herbicide. It is selectively absorbed by roots and foliage. It has an action mechanism of inhibiting the activity of acetyl CoA carboxylase. Haloxyfop-R-methyl is a selective herbicide and is used for preventing and killing various gramineous weeds in various broad-leaved crop fields. It has the characteristics of quick weed control, strong systemic action, high safety on crops and is widely used for preventing and removing gramineous weeds in broad-leaved crop fields, such as soybeans, groundnut, grapes, cotton, black gram, wheat, oil sunflowers, potatoes, vegetables and the like. Chemical structure of Haloxyfop-R-methyl is provided below:

[0030] Haloxyfop-R-Methyl

[0031] A compound of Formula I chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A- mesyl-2-nitrobenzamide is a selective herbicide, and the solubility in water depends on the pH value. It is mainly used for preventing and killing annual and perennial broadleaf weeds. It is selectively absorbed by leaves and roots. It has an action mechanism of inhibiting the activity of inhibiting protoporphyrinogen oxidase, leading to irreversible cell membrane damage. Chemical Structure of compound of Formula I is provided below: 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A^-mesyl-2-nitrobenzamide

[0032] A compound of Formula II chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate is a selective pre-emergence and postemergence herbicide, can be absorbed by plant roots, stems and leaves, conducts up and down in the plant body, plays a role in weeding in the vigorous meristematic cells, and is mainly used for preventing and killing broad-leaved weeds in the soybean field. It has an action mechanism of inhibiting the activity of acetohydroxyacid synthase in plants to interfere the synthesis of branched chain amino acid, and is mainly used for weeding soybeans and preventing and removing broadleaf weeds and certain gramineous weeds. Chemical Structure of compound of Formula II is provided below

[0033] Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate Thus, the present invention provides composition comprising above mentioned active ingredients and a novel method of preparing such composition, which composition is stable as well as provide desired bio-efficacy, synergy. Embodiments of the present invention may therefore ameliorate one or more of the above-mentioned problems.

[0034] OBJECTIVES AND ADVANTAGES OF THE INVENTION

[0035] The main objective of the present invention is to provide synergistic herbicidal composition for broad spectrum weed control in all stages of weed growth, from pre- emergence, early post emergence to late post emergence weed stage, in single shot application.

[0036] Another objective of the present invention is to provide a synergistic herbicidal compositioneffective for controlling undesired vegetation including weeds such as grassy weeds, broad leaved weeds, gramineous weeds and sedges in various crops.

[0037] Accordingly, the main objective of the present invention is to provide a stable synergistic herbicidal composition for weed control in all stages of weed growth.

[0038] It is another objective of the present invention to provide improved, stable and ready to use stable synergistic herbicidal composition having synergistic and better properties compared to prior art formulations or mixtures or compositions.

[0039] Yet another objective of the present invention is to provide a synergistic herbicidal composition which can be quickly absorbed by the treated leaves of the weeds.

[0040] It is another objective of the present invention to provide a novel and effective synergistic herbicidal composition for controlling the harmful weeds in plants.

[0041] It is another objective of the present invention to provide a novel and effective synergistic herbicidal composition which can be easily formulated.

[0042] It is another objective of the present invention to provide a novel and effective synergistic herbicidal composition which is ideal for weed resistance management and provides enhanced weed control efficacy. Thus, an objective of the present invention is to provide a novel and effective synergistic herbicidal composition and a method of controlling pre-emergence, early post emergence to late post emergence (3-12 leaf stage of weeds) weeds.

[0043] Another objective of the present invention is to provide a novel and effective synergistic herbicidal composition for improved broadleaf and grassy weed control without adversely affecting desirable plants.

[0044] Another objective of the present invention is to provide a novel and effective synergistic herbicidal composition which reduces the amount of chemical herbicidal agent necessary to obtain the acceptable weed control.

[0045] It is another objective of the present invention to provide effective control against resistant weeds and helps to eliminate the chances of re-emergence or germination of weeds.

[0046] It is another objective of the present invention to provide a novel and effective synergistic herbicidal composition which is ideal for weed resistance management and provides enhanced weed control efficacy and resist re-emergence of weeds.

[0047] It is another objective of the present invention to provide a novel and effective synergistic composition which provides a better control of weeds at lower use rates, and excellent residual control.

[0048] It is another objective of the present invention to provide a novel and effective synergistic composition which provide excellent crop safety in terms of no phytotoxicity and no adverse effect on germination or growth of succeeding crops.

[0049] Yet another objective of the present invention is to provide a method of improving plant health and increasing crop yield by using synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereofand C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof.

[0050] It is another objective of the present invention to provide a process for preparing a novel and effective synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof .

[0051] Yet another objective of the present invention is to provide a method of increasing yield in a crop by application of a novel and effective synergistic herbicidal composition.

[0052] Another objective of the present invention is to provide a novel and effective synergistic herbicidal composition which is more stable and has enhanced shelf life.

[0053] Another objective of the present invention is to provide a novel and effective herbicidal composition which is synergistic and thus helps in resistance management.

[0054] Another objective of the present invention is to provide one shot application of novel and effective synergistic herbicidal composition for killing / controlling highly resistant broad leaved weeds, grasses and sedges at lower application rates.

[0055] It is another objective of the present invention to provide a novel and effective synergistic herbicidal composition which has enhanced efficacy and penetration capacity.

[0056] Some or all these and other objective of the invention can be achieved by way of the invention described hereinafter.

[0057] ADVANTAGES OF THE INVENTION

[0058] 1. The synergistic herbicidal composition of the present invention provides weeds control in pre-emergence, early post emergence to late post emergence weed stage in single shot application.

[0059] 2. The synergistic herbicidal composition of the present invention is stable and has enhanced shelf life.

[0060] 3. The synergistic herbicidal composition of the present invention helps to delay, reduce and / or avoid the onset of herbicidal resistance or can be used on weeds already resistant to existing herbicides. 4. The synergistic herbicidal composition of the present invention provides broad spectrum control of weeds in a single shot application at lower use rates, and offers excellent residual control.

[0061] 5. The synergistic herbicidal composition of the present invention provides excellent crop safety in terms of no phytotoxicity and has no adverse effect on germination or growth of succeeding crops.

[0062] 6. The synergistic combination of the present invention resulted in significantly lower incidence of weeds in soybean crop as compared to the binary combination and untreated check.

[0063] 7. The synergistic combination of the present invention is significantly superior from its individual product specifically manufactured by inventor or readily available in market in reducing the weed incidence at 30, 45 and 60 days after treatment in soybean crop.

[0064] 8. The synergistic combination of the present invention provides improved crop yield as compared to the untreated control and binary and solo treatments applied in the soybean crop. Also found economical with higher Cost: Benefit Ratio.

[0065] 9. The synergistic combination shows no phytotoxicity effect on soybean crop.

[0066] 10. The results of experiments indicate that the synergistic combination is highly effective in controlling weeds and increasing production of soybean at lower doses of the products in the combination, thus the invention will be cost effective and safer to the environment.

[0067] SUMMARY OF THE INVENTION:

[0068] The present invention relates to a stable synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof, for broad spectrum weed control in all stages of weed growth. The present invention provides effective control of wide range of weeds or undesired vegetation in various crops. Herbicidal composition of the present invention is environmentally safe, stable, safe to handle, and cost effective.

[0069] In one embodiment of the present invention, the stable synergistic herbicidal composition comprises: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; b) compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and c) compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof.

[0070] In a preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof in the range of 0.1 to 50% by weight of the composition; b) compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; and c) compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 50% by weight of the composition.

[0071] In yet another embodiment of the present invention, the stable synergistic herbicidal composition comprising: a) Haloxyfop-R-methyl in the range of 0.1 to 50% by weight of the composition; b) compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; and c) compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 50% by weight of the composition.

[0072] In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 25 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 5 to 30% by weight of the composition; and c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 25 % by weight of the composition.

[0073] In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 30 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 5 to 40% by weight of the composition; and c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 25 % by weight of the composition.

[0074] In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop-R-methyl in the range of 0.1 to 25 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]- / V-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 5 to 30% by weight of the composition; and c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 20 % by weight of the composition.

[0075] In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop-R-methyl in the range of 0.1 to 30 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 5 to 40% by weight of the composition; and c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 25 % by weight of the composition.

[0076] In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 25 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 30% by weight of the composition; c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 20 % by weight of the composition and d) one or more agrochemically acceptable excipients. In a more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 30 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 40% by weight of the composition; c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 25 % by weight of the composition and d) one or more agrochemically acceptable excipients.

[0077] In much more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop-R-methyl, in the range of 0.1 to 25 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 30% by weight of the composition; c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 20 % by weight of the composition and d) one or more agrochemically acceptable excipients.

[0078] In much more preferred embodiment, the present invention provides a stable synergistic herbicidal composition comprising: a) Haloxyfop-R-methyl, in the range of 0.1 to 30 % by weight of the composition; b) Compound of Formula I i.e. 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-iV-mesyl-2- nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 40% by weight of the composition; c) Compound of Formula II i.e. Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof , in the range of 0.1 to 25 % by weight of the composition and d) one or more agrochemically acceptable excipients.

[0079] In a one embodiment of the present invention, amongst the salts, ester and derivatives of Haloxyfop, Haloxyfop-R-methyl is preferred.

[0080] In another embodiment of the present invention, Haloxyfop-R-methyl is present in the range of 0.1-30 % by weight of the composition.

[0081] In yet another embodiment of the present invention, the present herbicidal composition can be applied to various plants, crops including but not limited to such as wheat, sugarcane, cotton, cabbage, cauliflower, tomatoes, potatoes, leafy vegetables, oil crops, flowering ornamentals vine crops, fruit trees, soybeans, corn, groundnut, potatoes, sugar beets, black gram, onion, Rice(paddy), vegetables, and flax, as well as other crops.

[0082] DETAILED DESCRIPTION OF THE INVENTION

[0083] In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

[0084] All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs.

[0085] The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure. As used in the present disclosure, the forms "a,” "an," and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. It should also be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0086] The terms "comprises," "comprising," “including,” and “having,” are open ended transitional phrases and therefore specify the presence of stated features, integers, steps, operations, elements, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. The particular order of steps disclosed in the method and process of the present disclosure is not to be construed as necessarily requiring their performance as described or illustrated. It is also to be understood that additional or alternative steps may be employed.

[0087] The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total solution or composition unless otherwise specified.

[0088] The term “control” as used in the present disclosure and claims, means to prevent the appearance of undesired vegetation or to reduce its growth or vigor.

[0089] The term “active ingredient” (a.i.) or “active agent” used herein refers to that component of the composition responsible for control and killing of weeds.

[0090] The terms “plants” and “vegetation” include, but are not limited to, germinant seeds, emerging seedlings, plants emerging from vegetative propagules, and established vegetation.

[0091] The term “locus” as used herein shall denote the vicinity of a desired crop in which weed control, typically selective weed control, of weeds is desired. The locus includes the vicinity of desired crop plants wherein the weed infestation has either emerged or is yet to emerge.

[0092] The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

[0093] The term “non-crop” areas shall include airport, railway stations, metro areas, between trees, horticulture areas, industrial areas, etc The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.

[0094] “Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment.

[0095] The term “herbicide” is used herein to mean an active ingredient that kills, controls or otherwise adversely modifies the growth of plants. An herbicidal effective or vegetation controlling amount is an amount of active ingredient which causes a “herbicidal effect,” i.e., an adversely modifying effect and includes deviations from natural development, killing, regulation, desiccation, retardation, and the like.

[0096] The term "health of a plant" or "plant health" is defined as a condition of the plant and / or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased.

[0097] Increased yield can be characterized, among others, by the following improved properties of the plant: increased plant weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased leaf are index.

[0098] As per one embodiment, the active herbicidal compound as mentioned above to be used in the composition of the present invention, can be in the form of base or any salt form or ester form of the active which is known in the art.

[0099] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention.

[0100] It has been observed by the inventors of the present invention that the composition of present invention not only has enhances bio-efficacy and provides synergistic effect but also gives control of weeds for a longer duration as compared to solo and binary formulations of herbicides. In accordance with an embodiment of the present invention, there is provided a synergistic herbicidal composition comprising active ingredients present in the weight % range as given below:

[0101] In one embodiment of the invention, there is synergistic and efficacious control of weeds or unwanted vegetation affecting the plants and crops.

[0102] The present invention includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

[0103] In further embodiment of the present invention, the synergistic herbicidal composition of the present invention further comprises agriculturally acceptable excipients including but not limited to the group comprising surfactant / dispersing agent, anti-freezing agent, anti-foaming agent, wetting agent, suspension aid, antimicrobial / anti-bacterial agent, buffering agent, thickening agent / thickener, quick coating agent or sticking agents / sticker (also referred to as “stickers” or “binders”), spreader, binders, anti-caking agents, adjuvants, fillers, emulsifiers, colouring pigments, dyes, preservatives, buffering agent and solvent thereof. Additional components may also be included, e.g., protective colloids, adhesives, thickeners, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid additive, which complies with usual formulation techniques. Examples of dispersing agent used herein include but not limited to Sodium salt of naphthalene sulfonate condensate, sodium diisopropyl naphthalene sulfonate, Sodium alkyl naphthalene sulfonate formaldehyde condensate polyarylphenyl ether phosphate, tristyryl phenol ethylated, acrylic copolymer, ethoxylated tristryl phenol Sulphate, naphthalene sulfonic acid, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, polyalkelene glycol ether, ethoxylated fatty alcohol, Sodium polymethyl methacrylatnae, sodium polyacrylate, sodium lignosulphonate, calcium lignosulphonate, Sodium naphthalene formaldehyde condensate , alkylphenol polyoxyethylene ether, polycarboxylate, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, sodium polymethyl methacrylate, Polymethyl methacrylatepolyethylene glycol graft copolymer, Ethanol 2,2,2 -nitrilotris with alpha-(2,4,6-tris(l- phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2-ethanediyl) phosphate, Alkyl phenol Polyethanoxy Ether, 2-2- oxydiethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-15.0 % by weight of the composition.

[0104] Examples of wetting agent used herein include but not limited to tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block copolymers, sodium lauryl sulphate, sodium ligno sulphates, Ethanol 2,2,2 -nitrilotris with alpha- (2,4,6-tris(l-phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2-ethanediyl) phosphate, Polyethylene Polypropylene glycol mono butyl ether , Alkyl phenol Polyethanoxy Ether, 2-2- oxy diethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-10 % by weight of the total composition.

[0105] Examples of defoamer or antifoaming agent used herein include but not limited to silicon emulsion based anti-foam agents, Polydimethylsiloxane, Siloxane polyalkyleneoxide, , trisiloxane ethoxylates, silicone oil, silicone compound, C 10~C20 saturated fat acid compounds or C8~C 10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0106] Examples of antifreezing agent used herein include but not limited to glycol, propylene glycol, mono ethylene glycol, Glycerol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 0.1-15 % by weight of the composition.

[0107] Examples of antimicrobial or anti-bacterial agent used herein include but not limited to 1,2- benzisothiazolin-3-one, formaldehyde, sodium benzoate / Sodium o-phenylphenate, 5-chloro-2- methyl-4-isothiazolin-3-one & 2- methyl-4-isothiazolin-3-one, potassium sorbate or mixtures thereof and present in the range of 0.1-20 % by weight of the composition.

[0108] Examples of thickener / thickening agent used herein include but not limited to polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.1-10 % by weight of the composition.

[0109] Examples of solvent used herein include but not limited to heavy aromatic hydrocarbon, N- methyl pyrollidone(NMP), Di-methyl sulfoxide(DMSO), N- alcohol, alkyl amide, vegetable oil, mineral oil, aromatic solvents, water or mixtures thereof and present in the range of 0.1-90 % by weight of the composition.

[0110] Examples of emulsifier used herein include but not limited to nonionic surfactant of ethoxylated fatty acid type, such as ethoxylated fatty acid mono-, di- or triglycerides or ethoxylated dialkyl sulfosuccinate, Tri-styrenated phenol ethoxylate , blend of Calcium Alkyl benzene sulphonate and Tri-styrenated phenol ethxylate an alkylaryl sulfonate, a polyoxyethylene fatty acid ester, a polyoxyethylene sorbitol fatty acid ester, a polyoxyethylene castor oil and a polyoxyethylene hydrogenated castor oil., ethoxylated fatty alcohol type or a block copolymer comprising one or more alkylene oxide block type or mixtures thereof and present in the range of 0.1-25 % by weight of the composition.

[0111] Examples of filler used herein include but not limited to silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, fumed silica, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-90 % by weight of the composition. Examples of anti-caking agent used herein include but not limited to group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0112] Rheology modifiers are sometimes referred to as thickeners or thickening agents, but they do much more than just thicken a formulation. A good rheology modifier structures the formulation but when a force is applied it becomes flowable and easily poured. Examples of rheology modifier used herein include but not limited to xanthan gum, gum arabic, gun ghatti, gum karaya, gum tragacanth, guar gum, or locust bean gum; silica, silicon dioxide, attagel, agar, alginic acid or mixture thereof and present in the range of 0.1-10 % by weight of the composition.

[0113] Examples of Polymer(s) used herein include but not limited to polyisocyanate used is toluene- 2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMD A), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates and mixture thereof and present in the range of 0.1-10 % by weight of the composition.

[0114] Examples of carrier (s) used herein but not limited to (silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, fumed silica, talcum powder, lactose, ammonium sulphate and mixtures thereof and present in the range of 0.1-95 % by weight of the composition.

[0115] An adjuvant used in the present invention is any material that is added to an agrochemical formulation to enhance or modify the performance of the formulation. An adjuvant used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant.

[0116] In yet another embodiment of the present invention, the synergistic herbicidal composition is formulated as but not limited to Emulsifiable concentrate (EC), Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR Micro-emulsion concentrate (MEC), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW).

[0117] In yet another embodiment of the present invention, the invention further provides the process for preparation of the said synergistic herbicidal composition wherein, the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion concentrate (MEC), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW).

[0118] In yet another preferred embodiment of the present invention, the synergistic herbicidal composition is formulated as Wettable powder (WP).

[0119] In further embodiment, depending on the formulation type, the composition of present invention may comprise one or more liquid or solid carriers, appropriate surfactants, dispersants, protective colloids, emulsifiers, wetting agents and tackifiers and appropriate further auxiliaries which are customary for formulating crop protection products.

[0120] The composition or formulation according to the present invention has a reduced or zero phytotoxicity with respect to agricultural crops. This results in the present invention as effective in the selective control of weeds.

[0121] According to another embodiment of the present invention, there is also a process provided for the preparation of stable synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof for broad spectrum weed control in all stages of weed growth.

[0122] More preferably, the present invention relates to a stable synergistic herbicidal composition comprising A) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; B) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]-A- mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and C) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof for broad spectrum weed control in all stages of weed growth.

[0123] The present invention provides effective control of wide range of weeds or undesired vegetation in various crops.

[0124] In one embodiment, the composition according to the present invention acts synergistically to control weeds in various plants, crops.

[0125] In an embodiment, the composition of present disclosure can be used to control all kind of monocots, dicots, sedges weed or any undesired or harmful plants. The composition can also control annual and perennial weeds. The composition in accordance with the present invention can be used to control harmful weeds that are hard to kill and have attained resistance.

[0126] The composition in accordance with the present invention can be used to control wide array of weeds in non-cultivated areas, on paths, track systems, industrial areas ("industrial weed control") or the like.

[0127] The synergistic herbicidal composition of present invention controls all kind of monocots, dicots, gramineous and sedges weeds. The most common weeds controlled are selected from but not limited to Abutilon indicum, Acalypha indica, Acanthospermum hispidum, Achyranthes aspera, Aerva tomentosa, Ageratum conyzoides, Alhagi camelorum, Amaranthus hybridus, Amaranthus spinosus, Amaranthus viridis, Ammannia baccifera, Anagallis arvensis, Argemone mexicana, Artemisia nilagiricia, Asphodelus tenuifolius, Avena fatua, Avena ludoviciana, Bidens pilosa, Boerhaavia diffusa, Boerhavia repanda, Brachiaria sp., Brachiaria mutica, Brassica kaber, Bromus tectorum, Calotropis gigantea, Cannabis sativa, Carthamus axyacantha, Cassia tora, Celosia argentea, Centella asiatica, Chenopodium album, Chenopodium murale, Chloris barbata, Chrozophora rottlerii, Cichorium intybus, Cirsium arvense, Clitoria ternatea, Cnicus arvensis, Commelina benghalensis, Commelina communis, Convolvulus arvensis, Conyza canadensis, Corchorus acutangulus, Coronopus didymus, Crotalaria serice, Sphenochlea sp, Cucumis callosus, Cuscuta campestris, Cuscuta chinensis, Cynodon dactylon, Cyanotis axillaris, Cyperus esculenthus, Cyperus iria, Cyperus rotundus, Ageratrum, Dactyloctenium aegyptium, Datura stramonium, Cyperous sp. Daucus carota, Digera arvensis, Digitaria sanguinalis, Dinebra retroflexa , Dinebra arabica Echinochloa sp, Echinochola colonum, Echinochola crusgalli, Eclipta alba, Eichhornia crassipes, Elephantopus scaber, Cynodan sp. , Cynodon dactylon (Dhoob grass), Paspalum conjugalum (Hilo grass) , Cyperus spp., (Purplenut shedge), Digeria aruensis (False Amaranth), Digiteria sanguinalis, Eleusine indica, Borreriabispida, Conyzoids, Digitaria ciliaris, Eragrostis major, Euphorbia geniculata, jugatum, Euphorbia hirta, Pospalumcon, Fimbristylis miliacea, Fumaria indica, Gynandropsis gynandra, Euphobia spp, Heliotropium indicum, Ludwigia , Indigofera glandulosa, Echinocloa crusgalli (barnyard grass), Pnicum isochmi, Ipomea aquatica, Lantana camara, Lathyrus aphaca (Meadow Pea), Launaea asplenifolia, Cyperus difformis , Cyperus iria , Launaea nudicaulis, Leucas aspera, Marsilea quadrifoliata, Medicago denticulate, Mimosa pudica, Melilotus alba, Melilotus indica, Melilotus spp (Sweet clover), Ocimum canum, Oenothera biennis, Opuntia dillenil, Orobanche ramosa, Oryza longistaminata, Oryza sativa, Oxalis corniculata, Oxalis latifolia, Parthenium hysterophorus, Paspalum sanguinale, Phalaris minor, Phyllanthus niruri, Physalis minima, Polypogon monspeliensis, Portulaca oleracea, Paspalum, Prosopis juliflora, Eragrostit minor, Dactyloctenium eigyptium, Rumex dentatus, Saccharum spontaneum, Stearia glauca, Seteria viridis, Eluesine indica , Sida spinosa, Silene antirrhina, Sisymbrium irio, Solanum nigrum, Solanum surattense, Sonchus oleraceous, Sorghum halepense, Spergula arvensis, Sphenocleazeylanica Gaertn, Grassy weeds Digitaria sanguinalis, Striga asiatica, Dactylocteneum, Tagetes minuta, Trianthema sp. Trianthema monogyna, Trianthema portulacastrum, Phalaris minor (Little seed canary grass) Tribulus terrestris, Trigonelia polycerata, Digiteria, Echinocloa colona (jungle rice), Chenopodium album (Lambs quarter) , Setaria sp, parviflora , Vernonia cinerea, Fimbristlylis.Vicia, Coronpus, sativa, Borreria, Imperata, marginata, Rumes Sp. (Golden dock) , Xanthium strumarium, Brachiaria sp., Digitaria sanguinalis, Dinebra entice, Echinochloa sp., Eleusine indica, Eragrostis sp., Pnicum isochmi, Cyperus rotundus Commelina benghalensis Celosia argentea Digera arvensis Cucumis trigonus Cyprus iria, Parthenium hysterophorus, Acalypha indica, Phyllanthus niruri, Trianthema portulacashurm, Caesulia auxillaris, Echinochloa colona, Eleusine indica, Doctyloctenium aegyptium.

[0128] In some embodiments, the compositions and methods provided herein are utilized to control weeds in crops, including but not limited to direct- seeded, water-seeded and transplanted rice, wheat, barley, oats, rye, sorghum, soybean, green bean, garbanzo bean, com / maize, cotton, pastures, grasslands, rangelands, fallowland, fallow-bed prior to planting crops, tree, vine and fruit orchards, including, but not limited to, citrus, grapes, almond, apple, apricot, avocado, beechnut, Brazil nut, butternut, cashew, cherry, chestnut, chinquapin, crab apple, date, feijoa, fig, filbert, hickory nut, kiwi, loquat, macadamia nut, mayhaws, nectarine, olives, peach, pear, pecan, persimmon, pistachio, plum, pomegranates, prune, quince, and walnut; vegetables (e.g., onions, onions grown for seed, shallots, garlic, peppers, tomatoes, artichokes and cole crops); fruiting crops (e.g., blueberries, guava, papaya, strawberries, taro, blackberries and raspberries); perennial crops, plantation crops (including, but not limited to, coffee, cacao, rubber and palm oil) and non-crop (including turf, forestry, aquatics, industrial vegetation management (IVM), deciduous trees, conifers (seedbeds, transplants, container stock and plantations / windbreaks), fencerows, parking areas, tank farm and storage areas, rights-of-way and utility areas.

[0129] In an embodiment, the composition of the present invention may be used to control the target weeds among the field GMO (Genetically Modified Organism) and Non GMO varieties of including but not limited to, Soybean, Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticumaestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet, (Pennisetum glaucum), Sugarcane (Saccharum officinarum), Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linumusitatissimum), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus), Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum), Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapasubsprapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Aclypha indica, Caesulia auxillaris, Panicum isochmi, Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fenugreek (Trigonella foenum-graecum), Fennel (Foeniculum vulgare), Coriander(Coriandrum sativum), Ajwain (Trachyspermumammi), Psyllium (Plantago ovate), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Drumstick (Moringa oleifera), Coconut (Coco nucifera), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold (Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera (Gerbera jamesonii), Carnation (Dianthus caryophyllus), and the like.

[0130] In an embodiment, the composition of the present invention can be used to delay, reduce and / or avoid the onset of herbicidal resistance.

[0131] In one embodiment of the present invention, the present herbicidal composition controls various weeds in field crops, turf grass, horticulture & forestry, etc. In one embodiment of the present invention, the present herbicidal composition is stable and has enhanced shelf life.

[0132] In one embodiment of the present invention, the present herbicidal composition has enhanced efficacy and penetration capacity.

[0133] The composition of the present invention may also comprise safeners.

[0134] In one embodiment, the compositions described herein are employed in combination with one or more herbicide safeners, such as AD-67 (MON 4660), benoxacor, benthiocarb, brassinolide, cloquintocet (mexyl), cyometrinil, daimuron, dichlormid, dicyclonon, dimepiperate, disulfoton, fenchlorazole-ethyl, fenclorim, flurazole, fluxofenim, furilazole, harpin proteins, isoxadifen-ethyl, jiecaowan, jiecaoxi, mefenpyr-diethyl, mephenate, naphthalic anhydride (NA), oxabetrinil, R29148 and N -phenyl- sulfonylbenzoic acid amides, to enhance their selectivity.

[0135] In other embodiment of the present invention, safeners are present in the range of 0.1 to 10% by weight of the total composition.

[0136] In an embodiment, the composition of the present invention may be combined with at least another active ingredient such as those selected from but not limited to herbicide, insecticide, fungicide, biological agent, plant growth activator, fertilizers or combinations thereof.

[0137] The content of the excipients used in the present invention is not particularly limiting and may be determined by a skilled technician in the art according to the conventional protocols.

[0138] The rate of application of composition of present invention varies depending on, for example, the blending ratio of active ingredients, meteorological condition, a dosage form, an application time, an application method, an application place, weed to be controlled, and a target crop, in ordinary cases.

[0139] As per one embodiment, the active herbicidal compound as mentioned above to be used in the composition of the present invention, can be in the form of base or any salt form or ester form of the active which is known in the art. In another preferred embodiment, the composition of the present invention is applied in one shot application for killing / controlling highly resistant broadleaved weeds, grasses, gramineous weeds and sedges at lower application rates.

[0140] The process for preparing the present novel synergistic herbicidal composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However, all such variation and modification is still covered by the scope of present invention.

[0141] Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified systems or process parameters that may of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.

[0142] Representative example of the present composition of this invention is provided below and is not to be construed as limiting in any manner:

[0143] Compound of Formula I, referred herein pertains to 5-[(2-chloro-a,a,a-trifluoro-p-tolyl)oxy]- N-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof.

[0144] Compound of Formula II, referred herein pertains to Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof.

[0145]

[0146] Example 1. Compound of Formula I 20% + Haloxyfop-R-methyl 24% + Compound of

[0147] Formula II 1.5% WP

[0148] 1. CHEMICAL COMPOSITION:

[0149] 2. FORMULATION PROCESS a. Took china clay in the ribbon blender and started mixing. b. To the above, added Sodiumdiisopropyl naphthlene sulphonate, Sodium salt of naphthalene sulfonate condensate, Precipitated silica, Compound of Formula I technical, Haloxyfop-R-methyl technical and Compound of Formula II technical and mixed well. c. Then continued to mix the above solution till the material was completely homogenised. d. Then the above premix was passed through the Airjet mill at 6 to 7 kg / cm2of grinding pressure and 100 to 150 kg / hr feeding rate to get a particle size of D90 less than 20 microns. e. The grinded material was collected in post blender. f. Checked Quality parameter and packed desire packing.

[0150] 3. Stability Data

[0151] Compound of Formula I_20% + Haloxyfop-R-methyl 24% + Compound of Formula

[0152] II 1.5% WP

[0153] Evaluation of synergistic effect of herbicidal composition of the present invention

[0154] A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2.

[0155] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0156] XY

[0157] E = (X + Y) - -

[0158] 100 The synergistic action expected for a given combination of three active components can be calculated as follows:

[0159] (XY+YZ+XZ) (XYZ)

[0160] E = (X + Y + Z) - - + -

[0161] 100 10000

[0162] Where:

[0163] E represents expected percentage of herbicidal control for the combination of the two or three actives ingredients at defined doses (for example equal to x, y and z, respectively).

[0164] X is the percentage of herbicidal control observed by the compound (Compound of Formula I) at a defined dose (equal to x).

[0165] Y is the percentage of herbicidal control observed by the compound (Haloxyfop-R-Methyl) at a defined dose (equal to y).

[0166] Z is the percentage of herbicidal control observed by the compound (Compound of Formula II) at a defined dose (equal to z).

[0167] When the percentage of herbicidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

[0168] Observed control (%)

[0169] Ratio = -

[0170] Expected control (%)

[0171] Ratio of O / E > 1, synergism observed

[0172] The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting.

[0173] Experiment for Synergistic activity of combination product of present invention:

[0174] Example 1- Details of experiment on soybean crop:

[0175] Field experiment for synergistic activity of Compound of Formula I, Haloxyfop-R-methyl and Compound of Formula II for the control of weeds in soybean crop was conducted by the Research & Development Department of the inventor at farmer field, Ujjain (Madhya Pradesh).

[0176] To evaluate the synergistic effect, soybean (Variety: JS-2098) crop was sown in 4 m x 5 m plots maintaining 30 cm x 10 cm plant distance with three replications and in Randomized Block Design (RBD). The treatments were sprayed at 2-3 leaf stage of weed flora as WP formulation @ 500 g / ha with the help of Knapsack sprayer fitted with flat fan nozzle. Each active component was applied at four doses in different ternary and binary combinations. Solo components were also taken for comparison. The treatment details are as under:

[0177] The treatments T1 to T28 were used as seed treatment whereas no treatment was done for T29 control treatment. Observations for weeds such as Brachiaria sp., Digitaria sanguinalis, Dinebra arabica, Echinochloa sp., Eleusine indica, Eragrostis sp., Panicum isochmi, Euphorbia hirta, Commelina benghalensis, Dactyloctenium aegyptium, Digera arvensis, Trianthema sp., Phyllanthus niruri, Aclypha indica, Cyperus rotundus, Celosia argentea, Cucumis trigonus, Cyprus iria, Parthenium hysterophorus, Caesulia auxillaris etc. were recorded at 40 days after crop sowing (DAS) by observing weed population in an area of 0.5 x 0.5 m (0.25 m2) at 4 random spots per plot. The per cent weed control efficacy was calculated by the weed population per m2area. Based on the per cent weed control efficacy the

[0178] Expected control was calculated and compared with Observed control. The results of the trial have been presented here under in Table 1.

[0179] Table 1: Synergistic effect of combination product of the present invention (Compound of Formula I + Haloxyfop-R-methyl + Compound of Formula II) against weeds in soybean crop It is clearly evident from the data shown in above Table 1 for per cent weed control efficacy in soybean crop that the ternary combination composition of the present invention comprising Compound of Formula I, Haloxyfop-R-methyl and Compound of Formula II (T1 to T4) are synergistic for weed control with > 1 Colby’s Ratio. The binary combinations of two herbicides (Compound of Formula I + Compound of Formula II; Compound of Formula I + Haloxyfop- R-methyl; Haloxyfop-R-methyl + Compound of Formula II) T5 to T16 are compatible but synergistic effect shown is low for the control of weeds.

[0180] Experiment for Bio-efficacy evaluation of combination product of present invention:

[0181] For the ternary and binary combination based on Compound of Formula I, Haloxyfop-R-methyl and Compound of Formula II evaluation under field conditions, the basic test composition as Compound of Formula I 20% + Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP was manufactured specifically by the inventor. For ternary combination, Compound of Formula I 20% + Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP was used and for binary combination Compound of Formula I 20% + Haloxyfop-R-Methyl 24% WP, Compound of Formula 120% + Compound of Formula II 1.5% WP, Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP were used. The solo formulation of Compound of Formula I 20% WP, Haloxyfop-R-Methyl 24% WP, Compound of Formula II 1.5% WP and other formulations Haloxyfop R Methyl 10.5% w / w EC, Compound of Formula II 25% WP + Surfactant, Fluazifop-p-butyl 11.1% w / w + Compound of Formula I 11.1% w / w SL available in the market were used for comparison. Furthermore, these herbicide treatments were compared with untreated control treatments.

[0182] Example 2: Evaluation of the combination product of the present invention on soybean

[0183] The synergistic composition of the present invention Compound of Formula I 20% + Haloxyfop-R- Methyl 24% + Compound of Formula II 1.5% WP was evaluated on soybean crop variety JS 2098 at a farmer field, Ujjain. The spray was done at 2-3 leaf stage of weed flora following Randomized Block Design (RBD) with three replications maintaining a distance of 30 cm x 10 cm between plants and rows in 4 m x 5 m plots.

[0184] The observations were recorded for the following objectives.

[0185] Objectives:

[0186] 1. Bio-efficacy evaluation against weeds on soybean crop

[0187] 2. Bio-efficacy evaluation based on crop yield 3. Economics of treatments based on Cost: Benefit Ratio

[0188] 4. Phytotoxicity evaluation on soybean crop

[0189] Treatment details: Methodology: The treatments T1 to T15 and T18 were used as spray whereas no treatment was done for T19 control treatment. Hand operated Knapsack sprayer fitted with flat fan nozzle was used for spraying. The spray volume used was 500 liters per hectare.

[0190] Observation for weeds such as Brachiaria sp., Digitaria sanguinalis, Dinebra arabica, Echinochloa sp., Eleusine indica, Eragrostis sp., Panicum isochmi, Euphorbia hirta, Commelina benghalensis, Dactyloctenium aegyptium, Digera arvensis, Trianthema sp., Phyllanthus niruri, Aclypha indica, Cyperus rotundus, Celosia argentea, Cucumis trigonus, Cyprus iria, Parthenium hysterophorus, Caesulia auxillaris etc. was recorded at 30, 45 and 60 days after treatment based on weed population. For recording the weed population, an area of 0.5 x 0.5 m (0.25 m2) was marked at four spots in each treatment and weed observations were made from the same marked area and was worked out to calculate weed number per m2area. The data was expressed in terms of weed control efficacy calculated by the weed population per m2area. The crop yield was recorded at crop harvest. The observations for phytotoxicity to soybean crop at 30, 45 and 60 days after crop sowing were also recorded. Based on treatment application cost, market price of produce and net profit, the Cost: Benefit Ratio was calculated for the economics of ternary combination treatments. The data was subjected to statistical analysis of variance. Results are presented in Table 2, 3, 4.

[0191] Results:

[0192] Table 2: Field bio-efficacy evaluation of Compound of Formula I 20% + Haloxyfop-R- Methyl 24% + Compound of Formula II 1.5% WP against weeds of soybean crop

[0193] DAS - Days after sowing; DAT - Days after treatment

[0194] Table 3: Field bio-efficacy evaluation of Compound of Formula I 20% + Haloxyfop-R- Methyl 24% + Compound of Formula II 1.5% WP based on crop yield of soybean

[0195] DAS - Days after crop sowing Table 4: Phytotoxicity evaluation of Compound of Formula I 20% + Haloxyfop-R- Methyl 24% + Compound of Formula II 1.5% WP on soybean crop

[0196] From the example, it can be clearly seen that the combination of the present invention is superior for controlling the weeds at 30, 45 and 60 days after treatment (Table 2) in soybean crop as compared to the solo and binary compositions. Other registered formulated products available in the market, Fluazifop-p-butyl 11.1% w / w + Compound of Formula I 11.1% w / w

[0197] SL, Haloxyfop R Methyl 10.5% w / w EC and Compound of Formula II 25% WP + Surfactant evaluated were next in order of effectiveness after ternary combination products. The yield of soybean crop also improved in the ternary combination of Compound of Formula I 20% + Haloxyfop-R- Methyl 24% + Compound of Formula II 1.5% WP as compared to solo, binary and other registered products in market (Table 3). Also, the Cost: Benefit Ratio revealed that ternary combination Compound of Formula I 20% + Haloxyfop -R-Methyl 24% + Compound of Formula II 1.5% WP @ 500 g / ha was most economical with higher Cost: Benefit Ratio as compared to other treatments (Table 3).

[0198] The disclosed combination Compound of Formula I 20% + Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP @ 400, 500, 625 & 1000g / ha showed no phytotoxicity in the soybean crop even after 30, 45 and 60 days after crop sowing (Table 4).

[0199] It is evident from the above tables of examples that the combination composition of the present invention Compound of Formula 120% + Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP resulted in good control of overall weed flora in soybean with higher respective yields as compared to the reference standard products (binary compositions and solo products). The Cost: Benefit Ratio also showed that ternary combination Compound of Formula 120% + Haloxyfop-R-Methyl 24% + Compound of Formula II 1.5% WP @ 500 g / ha was most economical with higher Cost: Benefit Ratio as compared to other binary and solo treatments. Further, the composition of present invention is resulted synergistic.

[0200] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

I CLAIM:

1. A stable synergistic herbicidal composition for broad spectrum weed control in crops, comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof; b) a compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p- tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof; and c) a compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof.

2. The stable synergistic herbicidal composition as claimed in claim 1, comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; b) compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p- tolyl)oxy]-A-mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; and c) compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition.

3. The stable synergistic herbicidal composition as claimed in claims 1 to 2, which further comprises one or more agrochemically acceptable excipients.

4. The stable synergistic herbicidal composition as claimed in claim 3 wherein the agrochemically acceptable excipients comprises of surfactant / dispersing agent, wetting agent, defoamer or antifoaming agent, rheology modifier, anti-freezing agent, adjuvants, fillers, emulsifying agent, anti-microbial / anti-bacterial agents, buffering agent, quick coating agent or sticking agents, thickeners / thickening agents, spreader, carriers, binders, anti-caking agents, polymers, colouring agents, safener, solvents or mixtures thereof.

5. The stable synergistic herbicidal composition as claimed in claim 4, wherein the dispersing agent is selected from the group comprising Sodium salt of naphthalene sulfonatecondensate, , Sodium alkyl naphthalene sulfonate formaldehyde condensate, sodium diisopropyl naphthalene sulfonate, polyarylphenyl ether phosphate, tristyryl phenol ethylated, acrylic copolymer, ethoxylated tristryl phenol Sulphate, naphthalene sulfonic acid, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, polyalkelene glycol ether, ethoxylated fatty alcohol, Sodium polymethyl methacrylatnae, sodium polyacrylate, sodium lignosulphonate, calcium lignosulphonate, Sodium naphthalene formaldehyde condensate , alkylphenol polyoxyethylene ether, polycarboxylate, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, sodium polymethyl methacrylate, Polymethyl methacrylatepolyethylene glycol graft copolymer, Ethanol 2,2,2 -nitrilotris with alpha-(2,4,6-tris(l- phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2-ethanediyl) phosphate, Alkyl phenol Polyethanoxy Ether, 2-2- oxydiethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-10 % by weight of the composition.

6. The stable synergistic herbicidal composition as claimed in claim 4, wherein the wetting agent is selected form the group comprising tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block co-polymers, sodium lauryl sulphate, sodium ligno sulphates, Ethanol 2,2,2 -nitrilotris with alpha-(2,4,6-tris(l- phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2-ethanediyl) phosphate, Polyethylene Polypropylene glycol mono butyl ether , Alkyl phenol Polyethanoxy Ether, 2-2- oxydiethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-10 % by weight of the total composition.

7. The stable synergistic herbicidal composition as claimed in claim 4, wherein the defoamer or antifoaming agent is selected from the group comprising silicon emulsion based anti-foam agents, Polydimethylsiloxane, Siloxane polyalkyleneoxide, , trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

8. The stable synergistic herbicidal composition as claimed in claim 4, wherein the anti-freezing agent is selected from the group comprising glycol, propylene glycol, mono ethylene glycol, Glycerol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 0.1-15 % by weight of the composition.

9. The stable synergistic herbicidal composition as claimed in claim 4, wherein the antimicrobial or anti-bacterial agent is selected from the group comprising 1,2- benzisothiazolin-3-one, formaldehyde, sodium benzoate / sodium o-phenylphenate, 5-chloro-2- methyl-4-isothiazolin-3-one & 2- methyl-4-isothiazolin-3-one, potassium sorbate or mixtures thereof and present in the range of 0.1-20 % by weight of the composition.

10. The stable synergistic herbicidal composition as claimed in claim 4, wherein the thickener / thickening agent is selected from the group comprising polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.1-10 % by weight of the composition.

11. The stable synergistic herbicidal composition as claimed in claim 4, wherein the solvent is selected from the group comprising heavy aromatic hydrocarbon, N-methyl pyrollidone(NMP), Di-methyl sulfoxide(DMSO), N- alcohol, alkyl amide, vegetable oil, mineral oil, aromatic solvents, water or mixtures thereof and present in the range of 0.1-90 % by weight of the composition.

12. The stable synergistic herbicidal composition as claimed in claim 4, wherein the emulsifier is selected from the group consisting of a nonionic surfactant of ethoxylated fatty acid type, such as ethoxylated fatty acid mono-, di- or triglycerides or ethoxylated dialkyl sulfosuccinate, Tri-styrenated phenol ethoxylate , blend of Calcium Alkyl benzene sulphonate and Tri-styrenated phenol ethxylate an alkylaryl sulfonate, a polyoxyethylene fatty acid ester, a polyoxyethylene sorbitol fatty acid ester, a polyoxyethylene castor oil and a polyoxyethylene hydrogenated castor oil., ethoxylated fatty alcohol type or a block copolymer comprising one or more alkylene oxide block type or mixtures thereof and present in the range of 0.1-25 % by weight of the composition.

13. The stable synergistic herbicidal composition as claimed in claim 4, wherein the filler is selected from the group comprising silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, fumed silica, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-90 % by weight of the composition.

14. The stable synergistic herbicidal composition as claimed in claim 4, wherein the anti-caking agent is selected from the group comprising of group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

15. The stable synergistic herbicidal composition as claimed in claim 4, wherein the rheology modifier is selected from group comprising xanthan gum, gum arabic, gun ghatti, gum karaya, gum tragacanth, guar gum, or locust bean gum; silica, silicon dioxide, attagel, agar, alginic acid or mixture thereof and present in the range of 0.1-10 % by weight of the composition.

16. The stable synergistic herbicidal composition as claimed in claim 4, wherein the polymer(s) is / are selected from polyisocyanate used is toluene-2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMD A), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxy monocarboxy lie acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight poly diisocy nates and mixture thereof and present in the range of 0.1-10 % by weight of the composition.

17. The stable synergistic herbicidal composition as claimed in claim 4, wherein the carrier(s) is / are selected from silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, fumed silica, talcum powder, lactose, ammonium sulphate and mixtures thereof and present in the range of 0.1-95 % by weight of the composition.

18. The stable synergistic herbicidal composition as claimed in claim 4, wherein the safener is selected from group comprising AD-67 (MON 4660), benoxacor, benthiocarb, brassinolide, cloquintocet (mexyl), cyometrinil, daimuron, dichlormid, dicyclonon, dimepiperate, disulfoton, fenchlorazole-ethyl, fenclorim, flurazole, fluxofenim, furilazole, harpin proteins, isoxadifen-ethyl, jiecaowan, jiecaoxi, mefenpyr-diethyl, mephenate, naphthalic anhydride (NA), oxabetrinil, R29148 and N -phenyl- sulfonylbenzoic acid amides or mixture thereof and present in the range of 0.1 to 10 % by weight of the total composition.

19. The stable synergistic herbicidal composition as claimed in claim 1-18, wherein the use of said composition improves plant health and increases crop yield in the field.

20. The stable synergistic herbicidal composition as claimed in claim 1-18, provide one shot application of novel and effective synergistic herbicidal composition for for killing / controlling highly resistant broad leaved weeds, grasses, gramineous weeds and sedges at lower application rates.

21. The stable synergistic herbicidal composition as claimed in any one of the claims 1-18, wherein the composition is in form of Wettable powder (WP) formulation.

22. A stable Wettable Powder (WP) synergistic herbicidal composition comprising: a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the amount range of 0.1-50% by weight of the composition; b) Compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p- tolyl)oxy]-A-incsyl-2-nitrobcnzamidc or its agrochemically acceptable salts, esters and derivatives thereof, in the amount of 0.1-50% by weight of the composition; and c) Compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof, in the amount of 0.1-50% by weight of the composition.

23. A kit-of-parts comprising a plurality of components, wherein said plurality of components comprises:a) Haloxyfop or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; b) Compound of Formula I, chemically known as 5-[(2-chloro-a,a,a-trifluoro-p- tolyl)oxy]-A -mesyl-2-nitrobenzamide or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition; and c) Compound of Formula II, chemically known as Ethyl 2-[[[[(4-chloro-6-methoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate or its agrochemically acceptable salts, esters and derivatives thereof, in the range of 0.1 to 50% by weight of the composition.

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