400 tests / hour portable biochemical analyzer

Abstract

The present invention relates to a 400 tests / hour portable biochemical analyzer, comprising: a base plate; a reaction tray, which is arranged on the base plate; and a sample tray and a reagent tray, which are arranged close to the reaction tray, wherein a sample sampling pipette is arranged between the reaction tray and the sample tray, a reagent sampling pipette is arranged between the reaction tray and the reagent tray, and the sample sampling pipette and the reagent sampling pipette are each provided with a swing arm which can be retracted for storage; and power devices are provided below and configured for coaxial drive of the reagent tray, the sample tray and the reaction tray, respectively. During testing, the swing arm extends upwards from a pipette holder of the sampling pipette to the sampling height, and when the testing is completed, the swing arm is retracted and stored on the pipette holder, such that the overall height of the biochemical analyzer is reduced to further reduce the height of the whole unit, thereby improving the portability.

Description

400-speed portable biochemical analyzer

[0001] This application claims priority to the above-mentioned Chinese patent application filed with the China Patent Office on August 28, 2023, with application number 202311091179.1 and invention name “400-speed portable biochemical analyzer”, the entire contents of which are incorporated by reference into the above-mentioned application. Technical Field

[0002] The present invention relates to the field of medical testing technology, and more particularly to a 400-speed portable biochemical analyzer. Background Art

[0003] Fully automatic biochemical analyzers are often used in hospital laboratories, which include nearly 100 test items. To meet the requirements of a large number of test items, each test reagent corresponds to a different test item and needs to be tested on the fully automatic biochemical analyzer. Different test reagents are stored in different reagent compartments. Existing fully automatic biochemical analyzers use numbers to distinguish different reagent compartment positions. During actual operation, after the operator places a specific reagent into a specific reagent position on the reagent tray, it is necessary to set the parameters for the specific test item for that reagent position, including the added sample volume, reagent volume, detection wavelength, incubation time, reaction time, test type, etc.

[0004] However, due to the large number of test items and the relatively small number of reagent positions on the biochemical analyzer, each reagent position needs to frequently change the test items and temporarily re-set the parameters. Therefore, operating a fully automatic biochemical analyzer requires professional operators to set the parameters.

[0005] Free health checkups for the elderly, especially those in rural areas, involve 10 biochemical tests (12 in a few places). Public health health checkups are conducted regularly and centrally each year, requiring a large number of people to be tested and requiring in-depth visits to the grassroots level. Due to the lack of professionally trained operators at the grassroots level in rural areas, the parameters of biochemical analyzers are complex to set and the operation is cumbersome. Existing small biochemical analyzers suitable for transportation are semi-automatic or manual, which cannot meet the needs of large-scale health checkups. Fully automatic biochemical analyzers are large, heavy, and cumbersome to operate, making them inconvenient for large-scale health checkups in remote villages.

[0006] It should be pointed out here that the technical content provided in this section is intended to help those skilled in the art understand the present invention, and does not necessarily constitute prior art.

[0007] Summary of the Invention

[0008] In view of this, the purpose of the present invention is to provide a 400-speed portable biochemical analyzer to meet the needs of public health examinations.

[0009] In order to achieve the above object, the present invention provides the following technical solutions:

[0010] A 400-speed portable biochemical analyzer, comprising a base plate, a reaction tray disposed on the base plate, a sample tray and a reagent tray disposed proximate to the reaction tray, a sample sampling needle disposed between the reaction tray and the sample tray, and a reagent sampling needle disposed between the reaction tray and the reagent tray, the sample sampling needle and the reagent sampling needle both having retractable swing arms for storage;

[0011] Coaxially driven power devices are respectively provided below the reagent disk, the sample disk and the reaction disk.

[0012] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reagent disk has an R1 reagent area and an R2 reagent area staggeredly distributed around its circumference, and the R1 reagent area is a plurality of concentrically arranged fan-shaped areas, and the fan-shaped areas are used to place the R1 reagent kit;

[0013] The R2 reagent area includes a plurality of trapezoidal areas arranged between two adjacent sector-shaped areas and arranged along the radial direction of the reagent disk. The trapezoidal areas are used to place the R2 reagent kit.

[0014] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the sector-shaped area is a triangular sector-shaped area having a triangular sector-shaped cross section, and a plurality of the triangular sector-shaped areas form an inner ring structure;

[0015] The sidewall of the trapezoidal region is arranged close to the sidewall of the fan-shaped region, and the trapezoidal region is a curved trapezoidal structure with both the inner and outer sidewalls being arcuate walls;

[0016] The R1 kit is a fan-shaped kit that matches the fan-shaped area, and the R2 kit is a cambered trapezoidal kit that matches the trapezoidal area.

[0017] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the R2 reagent area includes four groups distributed circumferentially around the reagent disk, each group of the R2 reagent area includes two trapezoidal areas; three fan-shaped areas are arranged between two adjacent R2 reagent areas.

[0018] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reagent disk has a coaxially arranged inner ring reagent area and outer ring reagent area, the inner ring reagent area is the R2 reagent area, and a plurality of R2 reagent kits in a trapezoidal structure are arranged on the R2 reagent area; the outer ring reagent area is the R1 reagent area, and a plurality of R1 reagent kits in a trapezoidal structure are arranged on the R1 reagent area.

[0019] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reagent disc comprises a reagent kit holder and a reagent disc outer cylinder arranged on the reagent kit holder, and the R1 reagent area and the R2 reagent area are arranged on the reagent kit holder;

[0020] The substrate is fixed with a reagent disc power device that coaxially drives the reagent kit holder to rotate. The output end of the reagent disc motor is provided with a reagent kit code disc that monitors the position of the reagent kit holder. The substrate is fixed with a reagent kit photoelectric sensor that cooperates with the reagent kit code disc.

[0021] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reagent kit holder is a plastic reagent kit holder, and the reagent kit holder includes a reagent kit base plate connected to the reagent tray motor, and a reagent kit vertical plate extending from the reagent kit base plate for separating the R1 reagent area from the R2 reagent area.

[0022] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the sample tray includes a sample tube holder for arranging sample tubes; a sample tray outer cylinder provided on the base plate for protecting the sample tube holder;

[0023] A sample disk power device is fixedly mounted on the base plate for coaxially driving the sample tube holder to rotate. A sample disk code disk is arranged at the output end of the sample disk motor for monitoring the position of the sample tube holder. A sample disk photoelectric sensor that cooperates with the sample disk code disk is fixedly mounted on the base plate.

[0024] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reagent tray power device includes a first coupling sleeve coaxially arranged with the reagent tray holder, the lower end of the first coupling sleeve extending out of the reagent tray outer cylinder is provided with a first linkage gear and a reagent tray motor driving the first linkage gear to rotate; the reagent tray code disk is fixedly mounted on the first linkage gear;

[0025] The sample tray power device includes a second coupling sleeve coaxially arranged with the sample tube holder, the second coupling sleeve extending out of the lower end of the sample tray outer tube is provided with a second linkage gear and a sample tray motor driving the second linkage gear to rotate; the sample tray code disk is fixedly mounted on the second linkage gear.

[0026] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the reaction tray comprises an incubation pot fixedly mounted on the base plate and a cuvette holder arranged in the incubation pot and having a disc-shaped structure, wherein a holder support seat is coaxially arranged in the middle of the cuvette holder;

[0027] A reaction disk power device is arranged at the lower end of the bracket support seat; the reaction disk power device includes a third linkage gear linked to the bracket support seat, and a reaction disk motor that drives the third linkage gear to rotate; a reaction disk code disk for monitoring the position of the reaction cup bracket is fixed on the third linkage gear.

[0028] Preferably, in the above-mentioned 400-speed portable biochemical analyzer, the outer ring of the incubation pot is provided with an annularly arranged incubation track;

[0029] The cuvette holder has an annular outer ring that falls into the incubation track, and a plurality of cuvette placement holes for placing cuvettes are evenly distributed on the annular outer ring;

[0030] The middle portion of the reaction cup bracket is provided with a rotation driving portion connected to the bracket support seat, and the outer periphery of the rotation driving portion is connected to the annular outer ring.

[0031] The present invention provides a 400-speed portable biochemical analyzer, comprising a base plate, a reaction tray disposed on the base plate, a sample tray and a reagent tray disposed proximate to the reaction tray, a sample sampling needle disposed between the reaction tray and the sample tray, and a reagent sampling needle disposed between the reaction tray and the reagent tray, each of which has a retractable swing arm for storage; and a coaxially driven power device disposed below each of the reagent tray, the sample tray, and the reaction tray. To meet the requirements of portability, the 400-speed biochemical analyzer employs independent sample and reagent trays in its sample detection structure. A reagent sampling needle and a sample sampling needle are disposed on the base plate, cooperating with the reaction tray on the base plate to enable sampling and testing of samples and reagents. Both the reagent sampling needle and the sample sampling needle utilize retractable swing arms. During testing, the swing arms of the two extend upward from the sampling needle holder to a sampling height. After testing is complete, the swing arms retract and retract onto the holder, thereby reducing the overall height of the biochemical analyzer and improving portability. Furthermore, to adapt to the characteristics of public health testing involving fewer testing items, the independently arranged reagent tray, sample tray and reaction tray are coordinated, and all three adopt an independent drive structure. The drive structure is arranged as a coaxial drive structure to reduce the complexity of the drive structure, which can effectively reduce the height of the reagent tray, sample tray and reaction tray, thereby cooperating with the reagent sampling needle and sample sampling needle to further reduce the height of the whole machine and improve portability. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] The above and other objects, features and advantages of the present invention will become more apparent through the following description of the embodiments of the present invention with reference to the accompanying drawings, in which:

[0033] FIG1 is a schematic diagram of the structural arrangement of a 400-speed portable biochemical analyzer provided by the present invention;

[0034] FIG2 is a schematic diagram of the axial structural arrangement of the 400-speed portable biochemical analyzer provided by the present invention;

[0035] FIG3 is a schematic diagram of a second arrangement of the reagent tray of the 400-speed portable biochemical analyzer provided by the present invention;

[0036] FIG4 is a cross-sectional view of the installation structure of the reaction disk in the 400-speed portable biochemical analyzer provided by the present invention;

[0037] FIG5 is a cross-sectional view of the installation structure of the sample tray in the 400-speed portable biochemical analyzer in FIG1;

[0038] FIG6 is a schematic cross-sectional view of the incubation pot of the 400-speed portable biochemical analyzer in FIG1 ;

[0039] FIG7 is a schematic structural diagram of the incubation pot in FIG6 . DETAILED DESCRIPTION

[0040] The present invention will be described below based on examples, but the present invention is not limited to these examples.

[0041] Public health physical examination items generally include 10 or 12 items. The biochemical items are relatively clear and the number is small. In the use of reagents, 8 items including alanine aminotransferase (ALT), aspartate aminotransferase (AST), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), urea nitrogen (UREA), creatinine (CRE), total bilirubin (TBIL) and direct bilirubin (DBIL) are double-reagent items; glucose (GLU), triglycerides (TG), albumin (ALB) and total cholesterol (THCO4) are single-reagent items.

[0042] Double-reagent detection projects require two reagents to jointly undergo a biochemical reaction with the blood sample (specimen), and the content of the detected substance is calculated based on the optical changes of the reaction system. To avoid the working solution from being unable to guarantee long-term effectiveness after pre-mixing, the two reagents are only temporarily mixed together during the reaction. Single-reagent detection projects only require one reagent to undergo a biochemical reaction with the blood sample (specimen), and the content of the detected substance is calculated based on the optical changes of the reaction system. In biochemical analysis instruments, a single reagent is usually defined as only the R1 reagent, that is, when the sample is added to the R1 reagent, the reaction starts immediately; a double reagent is defined as two reagents, R1 and R2. The sample is first added to the reagent R1 to participate in the reaction, and then the reagent R2 is added after incubation for further reaction to achieve the detection purpose. Usually, R1 reacts with the sample to remove interference or prepare for further reaction after the addition of R2.

[0043] As shown in FIG1 , FIG1 is a schematic diagram of the structural arrangement of a 400-speed portable biochemical analyzer provided by the present invention; FIG2 is a schematic diagram of the axial side structural arrangement of a 400-speed portable biochemical analyzer provided by the present invention;

[0044] Figure 3 is a schematic diagram of a second arrangement of the reagent tray of the 400-speed portable biochemical analyzer provided by the present invention; Figure 4 is a cross-sectional view of the installation structure of the reaction tray in the 400-speed portable biochemical analyzer provided by the present invention; and Figure 5 is a cross-sectional view of the installation structure of the sample tray in the 400-speed portable biochemical analyzer in Figure 1.

[0045] The biochemical analyzer provided in this application is used in public health physical examination projects and can simultaneously perform dual-reagent detection projects and single-reagent detection projects.

[0046] The 400-speed portable biochemical analyzer provided in this embodiment includes a base plate 1, a reaction tray 2 arranged on the base plate 1, a sample tray 3 and a reagent tray 4 arranged near the reaction tray 2, a sample sampling needle 5 arranged between the reaction tray 2 and the sample tray 3, and reagent sampling needles 61 and 62 arranged between the reaction tray 2 and the reagent tray 4. The sample sampling needle 5 and the reagent sampling needles 61 and 62 each have a retractable swing arm for storage; and coaxially driven power devices are provided below the reagent tray 4, the sample tray 3, and the reaction tray 2. To meet the need for portability, the 400-speed biochemical analyzer utilizes independent sample trays 3 and reagent trays 4 for sample testing. A reagent sampling needle and a sample sampling needle are arranged on the base plate 1, cooperating with the reaction tray 2 on the base plate 1 to enable sample and reagent sampling and testing. Both the reagent sampling needle and the sample sampling needle utilize retractable swing arms. During testing, the swing arms extend upward from the sampling needle holder to the sampling height. After the test is complete, the swing arms retract and retract onto the needle holder, thereby reducing the overall height of the biochemical analyzer and improving portability. Furthermore, to accommodate the limited number of test items involved in public health testing, the independently arranged reagent tray 4, sample tray 3, and reaction tray 2 all utilize independent drive structures, arranged as coaxial drive structures to reduce the complexity of the drive structures. This effectively reduces the height of the reagent tray 4, sample tray 3, and reaction tray 2, thereby cooperating with the reagent sampling needle and sample sampling needle to further reduce the overall height of the analyzer and improve portability.

[0047] In a specific embodiment of the present case, the reagent disk 4 has an R1 reagent area 41 and an R2 reagent area 42 that are staggered around its circumference. The R1 reagent area 41 is a plurality of concentrically arranged fan-shaped areas 411, and the fan-shaped areas are used to place the R1 reagent kit 4110; the R2 reagent area 42 includes a plurality of trapezoidal areas 412 arranged between two adjacent fan-shaped areas 411 and arranged along the radial direction of the reagent disk 4, and the trapezoidal areas are used to place the R2 reagent kit 4120.

[0048] To adapt to the public health physical examination items, which generally include 10 or 12 biochemical test requirements, the reagent tray needs to meet the layout requirements of both R1 reagent and R2 reagent. At the same time, R1 reagent and R2 reagent adopt different reagent kit structures to reduce the difficulty of identifying different reagents in physical examination items.

[0049] Specifically, the reagent disk 4 is provided with an R1 reagent area 41 and an R2 reagent area 42, which are arranged alternately along the circumference of the reagent disk 4. The reagent area is used to place the reagent kit. Considering that the annular area arranged around the circumference of the reagent disk is divided into multiple sector-shaped areas, the R1 reagent area 41 is arranged within the sector-shaped area. Correspondingly, the R1 reagent area 41 is used to place the R1 reagent kit 4110, and the R1 reagent kit has a sector-shaped structure.

[0050] The R2 reagent area 42 occupies a sector-shaped area. According to the reagent dosage requirements in the public health testing project, an R2 reagent area 42 is located in a sector-shaped area. The sector-shaped area further divides the radial direction of the reagent disc into multiple trapezoidal areas. Correspondingly, the R2 reagent kit 4120 is designed to correspond to the structure of the trapezoidal area, and the R2 reagent kit 4120 is arranged in the trapezoidal area. It can be understood that the R2 reagent area is further divided into multiple trapezoidal areas in the radial direction. In order to achieve the versatility of the trapezoidal area, the R2 reagent area can be processed into an approximately trapezoidal structure so that the span in the width direction is close, rather than a sector-shaped structure with the same structure as the R1 reagent area.

[0051] In another embodiment of the present case, according to the usage of R1 reagent and R2 reagent in public health testing projects, the usage of R1 reagent is more than that of R2 reagent, and the reagent disk is divided into multiple sector-shaped areas. Specifically, the reagent disk 4 is divided into triangular sector-shaped areas with triangular sector-shaped cross-sections as a whole, and multiple triangular sector-shaped areas form an inner ring structure; to adapt to the spacing arrangement structure of the R1 reagent kit 411 and the R2 reagent kit 412, the R1 reagent kit 411 is arranged in the sector-shaped area, and the R1 reagent kit 411 also has a fan-shaped cross-section and is directly fixed on the reagent disk bracket 43.

[0052] The sector-shaped area for placing the R2 reagent is further divided into two trapezoidal areas along the radial direction of the reagent disk. The trapezoidal area and the sector-shaped area are both located on the reagent reagent holder 43. The reagent reagent holder 43 is arranged close to the side wall of the trapezoidal area and the side wall of the sector-shaped area. The trapezoidal area is a curved trapezoidal structure with both the inner and outer wall surfaces being arc walls.

[0053] Furthermore, the R1 reagent kit 4110 is a fan-shaped reagent kit that cooperates with the fan-shaped area, and the R2 reagent kit 4120 is a cambered trapezoidal reagent kit that cooperates with the trapezoidal area.

[0054] The reagent tray 4 is supported and protected by its outer reagent tray cylinder 44. A reagent tray holder 43 is placed inside the reagent tray 4, and the reagent kits are loaded on the reagent tray holder 43. To further reduce the structural space occupied by the reagent tray holder 43, a fan-shaped area for arranging the R1 reagent kit and a trapezoidal area for arranging the R2 reagent kit are provided on the reagent tray holder 43.

[0055] The sector area is designed as a triangular sector area with a triangular sector cross section. The inner circles of the multiple triangular sector areas form a central mounting cylinder of the reagent disc holder 43 for arranging the driving device.

[0056] In a preferred embodiment of the present case, the R2 reagent area 42 includes four groups distributed at circumferential intervals around the reagent disk, and each group of R2 reagent areas 42 includes two trapezoidal areas; three fan-shaped areas are arranged between two adjacent R2 reagent areas 42. In order to meet the needs of public health detection projects, the present embodiment sets the R2 reagent areas 42 into four groups, each group consisting of two trapezoidal areas along the radial direction of the reagent disk 4, then, 8 R2 reagent areas can be formed on the reagent disk 4. Three fan-shaped areas are arranged between two adjacent R2 reagent areas 42, then, 12 trapezoidal areas can be arranged on the reagent disk 4. When the reagent disk provided in the present application is used to arrange R1 reagents and R2 reagents, the arrangement of 12 R1 reagent kits 4110 and 8 R2 reagent kits 4120 can be achieved, which meets the biochemical detection requirements of the 400-speed biochemical analyzer.

[0057] In another preferred reagent disk arrangement structure of the present case, the reagent disk 4 has a coaxially arranged inner ring reagent area 4121 and an outer ring reagent area 4111, the inner ring reagent area 4121 is the R2 reagent area, and a plurality of R2 reagent kits in a trapezoidal structure are arranged on the R2 reagent area; the outer ring reagent area 4111 is the R1 reagent area, and a plurality of R1 reagent kits in a trapezoidal structure are arranged on the R1 reagent area.

[0058] The reagent tray 4 is used to store detection reagents, and the arrangement structure of the R1 reagent area and the R2 reagent area thereon is used to reduce the occupied area of ​​the reagent tray so as to reduce the overall volume of the 400-speed biochemical analyzer. In particular, since the 400-speed biochemical analyzer given in this embodiment is dedicated to public health physical examination biochemical items, the detection items include 10-12 determined detection items, and the detection process is large-scale centralized detection, and the consumption of reagents and consumables is fast. By dividing the reagent tray into the R1 reagent area and the R2 reagent area, the two are arranged in the inner ring reagent area 4121 and the outer ring reagent area 4121 on the inner circle and outer circle of the reagent tray. At the same time, considering that the R1 reagent area and the R2 reagent area are both arranged circumferentially around the reagent tray, the R1 reagent area is arranged with an R1 reagent kit, which is surrounded by a plurality of R1 reagent kits with a trapezoidal structure; correspondingly, the R2 reagent area is arranged with a plurality of R2 reagent kits with a trapezoidal structure.

[0059] It can be understood that the R1 reagent and R2 reagent have different usage amounts due to different detection items. The reagents with relatively small usage amounts or applied to fewer detection items are arranged in the inner ring. In this embodiment, the R2 reagent area is preferably arranged in the inner ring reagent area. By controlling the radial lengths of the R1 reagent area and the R2 reagent area, the usage amounts of the R1 reagent and R2 reagents can be matched and the test kits can be distinguished.

[0060] In a specific embodiment of the present case, the reagent disk 4 includes a reagent kit support 43 and a reagent disk outer cylinder 44 arranged on the reagent kit support 43 , and the R1 reagent area 41 and the R2 reagent area 42 are arranged on the reagent kit support 43 .

[0061] A reagent disc power device 46 is fixedly mounted on the base plate 1 for coaxially driving the reagent kit holder 43 to rotate. A reagent kit code disc 462 is arranged at the output end of the reagent disc motor 461 for monitoring the position of the reagent kit holder. A reagent kit photoelectric sensor 463 is fixedly mounted on the base plate 1 for cooperating with the reagent kit code disc 462.

[0062] The reagent disk outer cylinder 44 is fixed on the base plate 1, and the reagent reagent holder 43 is rotatably arranged in the reagent disk outer cylinder 44. The middle mounting cylinder of the reagent reagent holder 42 is connected to the reagent disk power device 46. Specifically, the reagent disk power device 46 includes a reagent disk motor 461 fixed on the base plate 1 and a first linkage gear provided at the power output end of the reagent disk motor 461. The first linkage gear is connected to the reagent disk driving wheel 464 connected to the reagent disk motor 461, and drives the reagent disk driven wheel 465 to output power through the transmission belt 466. The reagent disk driven wheel 465 is connected to the middle mounting cylinder of the reagent reagent holder 43 through the first coupling sleeve 467. The two ends of the outer ring of the first coupling sleeve 467 are respectively connected to the reagent disk driven wheel 465 and the reagent reagent holder 43. A rotating support shaft is provided in the middle of the first coupling sleeve 467 and fixed to the base plate 1.

[0063] By setting a first coupling sleeve 467 between the reagent tray 4 and the base plate 1, the reagent tray power device 46 drives the reagent tray bracket 43 to rotate through the reagent tray driving wheel 464 and the reagent tray driven wheel 465, thereby achieving position adjustment and sampling of the reagents in the reagent tray.

[0064] The reagent kit driven wheel 465 rotates synchronously with the reagent kit holder 43, and the reagent kit code disk 462 is fixedly installed on the reagent kit driven wheel 465. The reagent kit photoelectric sensor 463 extends from the substrate 1. The rotation position of the reagent kit holder 43 is monitored by the reagent kit photoelectric sensor 463 and the reagent kit code disk 462 to sample the reagent during the biochemical detection process.

[0065] In a preferred embodiment of the present case, in order to further optimize the layout space of the reagent disc power device 46, a reagent disc support column that supports the first coupling sleeve 467 and the reagent disc outer cylinder 44 is supported on the base plate 1 by a support column, and the reagent disc support column further supports the reagent disc adapter plate 47 located between the reagent disc outer cylinder 44 and the base plate 1. The reagent disc adapter plate 47 supports the first coupling sleeve 467 after supporting the reagent disc power device 46 to a certain height, thereby reducing the space occupied by the components below the reagent disc, and compressing the reagent disc power device 46 to be stored between the reagent disc outer cylinder 44 and the reagent disc adapter plate 47.

[0066] In this embodiment, the reagent tray holder 43 is made of plastic and includes a reagent tray base plate 431 connected to the reagent tray power unit 46, and a reagent tray riser 432 extending from the reagent tray base plate 431 to separate the R1 reagent area 41 from the R2 reagent area 42. To further reduce the space occupied by the reagent tray 4 and accommodate the 10-12 tests typically performed on public health testing programs, the reagent tray holder 43 is constructed of plastic and comprises the reagent tray base plate 431 and the reagent tray riser 432. The reagent tray riser 432 separates the space above the reagent tray base plate 431 to form the R1 reagent area 41 and the R2 reagent area 42. Furthermore, in order to improve the supporting strength of the reagent kit stand for the R1 reagent kit 4110 and the R2 reagent kit 4120, supporting ribs are extended in the thickness direction of the reagent kit stand 432. After the R1 reagent kit 4110 and the R2 reagent kit 4120 are loaded into the reagent kit holder 43, the supporting ribs provide support, thereby improving the stability of the supporting structure of the R1 reagent kit 4110 and the R2 reagent kit 4120.

[0067] It can be understood that the reagent kit stand 432 also includes a middle reagent kit stand 433 that surrounds the middle mounting cylinder, a circumferential reagent kit stand 434 that surrounds the outer circle of the reagent kit bracket 43, and a vertical reagent kit stand 432 that extends radially along the radial direction of the reagent kit bracket 43. The inner side of the vertical reagent kit stand 432 is connected to the middle reagent kit stand 433, and the outer side is connected to the circumferential reagent kit stand 434. The middle reagent kit stand 433, the circumferential reagent kit stand 434 and the vertical reagent kit stand 432 are all fixedly mounted on the reagent kit base plate 431.

[0068] In order to avoid the torsional resistance of the reagent kit holder 43 during the rotation of the reagent kit holder 43, a metal reagent kit holder tray 47 is arranged under the reagent kit base plate 431, and the first coupling sleeve 467 supports the reagent kit holder 43 through the reagent kit holder tray 47, thereby ensuring the rotation consistency of the reagent kit holder 43 during the rotation driven by the reagent tray power device 46.

[0069] In a specific embodiment of the present invention, the sample tray 3 includes a sample tube rack 31 for arranging sample tubes; and a sample tray outer cylinder 32, disposed on the base plate 1, to protect the sample tube rack 31. The sample tube rack 31 comprises an upper multi-perforated plate 311 and a lower sample tube tray 312. The upper multi-perforated plate 311 and the sample tube tray 312 are assembled together by a plurality of struts 313 therebetween. Each hole in the upper multi-perforated plate 311 serves as a sample tube mounting hole. A sample tube support 314 is fixedly mounted on the sample tube tray 312 corresponding to each sample tube mounting hole. Sample tubes 315 are inserted into the sample tube rack 31 through the sample tube mounting holes, with the sample tube support 314 clamping the bottom of the sample tube 315 in place.

[0070] A sample disk power device 33 is fixedly mounted on the base plate 1 to coaxially drive the sample tube holder 31 to rotate. A sample disk code disk 34 is arranged at the output end of the sample disk motor to monitor the position of the sample tube holder. A sample disk photoelectric sensor 35 is fixedly mounted on the base plate 1 to cooperate with the sample disk code disk 34.

[0071] The sample tray power device 33 is also provided with a sample tray motor and a second linkage gear. The second linkage gear includes a sample tray driving wheel (not shown) and a sample tray driven wheel 332 driven by a belt 331. The sample tray driven wheel 332 is connected to the sample tube holder through a second coupling sleeve 35. Preferably, the upper end of the second coupling sleeve 36 is connected to the middle part of the upper porous plate 311, and the lower end is fixed to the sample tray driven wheel 332. The rotation support shaft of the second coupling sleeve 36 is fixed to the base plate 1 to provide rotation support for the second coupling sleeve 36.

[0072] Furthermore, a sample tray adapter is arranged below the sample tray 3, the rotation support shaft of the second connecting sleeve 36 is installed on the sample tray adapter, and the sample tray power device 33 is arranged on the sample tray adapter, thereby reducing the space occupied below the sample tray.

[0073] Furthermore, a sample tray code disk 34 and a sample tray photoelectric sensor 35 cooperating therewith are arranged below the sample tray 3. In a preferred structure, the sample tray code disk 34 is fixed on the sample tray driven wheel 331, and the sample tray photoelectric sensor 35 extends from the base plate 1 and cooperates with the sample tray code disk 34 to monitor the rotation position and rotation angle of the sample tray 3 to accurately obtain the position of each sample tube on the sample tray bracket.

[0074] As shown in FIG6 and FIG7, FIG6 is a schematic cross-sectional view of the incubation pot of the 400-speed portable biochemical analyzer in FIG1; FIG7 is a schematic structural view of the incubation pot in FIG6.

[0075] In a specific embodiment of the present case, the reaction tray 2 includes an incubation pot 21 fixed on a base plate and a cuvette holder 22 arranged in the incubation pot 21 and having a disc-shaped structure. A holder support 23 is coaxially arranged in the middle of the cuvette holder 22.

[0076] A reaction disk power unit 24 is arranged at the lower end of the bracket support base 23. The reaction disk power unit 24 includes a third linkage gear linked to the bracket support base 23 and a reaction disk motor that drives the third linkage gear to rotate. A reaction disk code disk 25 for monitoring the position of the reaction cup bracket is fixedly mounted on the third linkage gear.

[0077] In a specific embodiment of the present case, the outer ring of the incubation pot 21 is provided with an annular incubation track 211;

[0078] The cuvette holder 22 has an annular outer ring that falls into the incubation track 211, and a plurality of cuvette placement holes 221 for placing cuvettes are evenly distributed on the annular outer ring; the middle part of the cuvette holder 22 has a rotating drive part connected to the holder support seat, and the outer periphery of the rotating drive part is connected to the annular outer ring.

[0079] In this embodiment, the reaction tray 2 includes an incubation pot 21 fixedly mounted on the base plate 1. A cuvette holder 22 is arranged in the incubation pot 21. A holder support 23 is coaxially arranged in the middle of the cuvette holder 22. The holder support 23 is fixedly connected to the disc-shaped cuvette holder 22.

[0080] A reaction disk driving device 24 is arranged at the bottom of the incubation pot 21 , comprising a reaction disk motor, a reaction disk driving wheel connected to the reaction disk motor and the third coupling sleeve 25 , and a reaction disk driven wheel 241 .

[0081] The outer ring of the incubation pot 21 is provided with an annular incubation track 211;

[0082] A plurality of cuvette placement holes 221 are evenly distributed on the annular outer ring of the cuvette holder 22 . The cuvette placement holes 221 and the incubation track 211 are used to incubate the cuvette.

[0083] A cuvette holder is arranged in each cuvette placement hole 221. After the cuvettes are placed in the cuvette placement holes 221 one by one, the bottom of the cuvette falls on the incubation track 211. By rotating the cuvette holder 22, the cuvettes on the cuvette holder 22 can be continuously incubated and switched to different workstations.

[0084] In this embodiment, the middle part of the reaction cup holder 22 is a holder support seat 23, which is connected to the top end of the third coupling sleeve 25 and serves as the rotation driving part of the reaction cup holder 22. Preferably, the holder support seat 23 is a rotation driving part with a disc-shaped structure, and its radial outer ring is connected to the reaction cup holder 22.

[0085] The center of the cuvette holder 22 houses a holder support 23, which transmits the rotational drive force. The incubation pot 21 is coaxially arranged with the holder support 23. The bottom of the third coupling sleeve 25 extends beyond the bottom of the incubation pot 21, providing both axial support for the cuvette holder 22 and transmitting its rotational drive force. Specifically, the reaction disk motor is located at the bottom of the incubation pot 21. The third linkage gear comprises a reaction disk driving pulley and a reaction disk driven pulley 241, located at the drive end of the reaction disk motor and connected by a conveyor belt 242. The reaction disk driven pulley 242 is connected to the third coupling sleeve 25.

[0086] A reaction disc code disc 26 is coaxially arranged on the reaction disc driven wheel 241, and a reaction disc photoelectric sensor extends from the base plate 1. The reaction disc code disc 26 cooperates with the reaction disc photoelectric sensor to rotate with the reaction disc driven wheel to monitor the rotation position of the reaction cup holder to obtain the position of different reaction cups for taking and placing samples and reagents.

[0087] The incubation pot 21 is provided with an incubation track 211, which is filled with incubation liquid and uses a water bath to maintain the temperature of the reaction cups. A concave mounting groove 213 is provided on the outer periphery of the incubation pot 21. An insulating outer layer is also fixed to the outer periphery of the incubation pot 21. The inner ring of the insulating outer layer is provided with insulating protrusions, which are pressed tightly into the mounting groove. This not only helps to locate the insulating outer layer and the incubation pot 21 in the installation position, but also increases the insulation thickness of the insulating outer layer, thereby improving the heat preservation capacity of the incubation pot.

[0088] Furthermore, the outer insulation layer comprises multiple segments arranged at intervals around the periphery of the incubator. By configuring the outer insulation layer and the incubator 21 as a segmented assembly structure, space is reserved for installing water inlet channels, drainage channels, and thermal protection structures on the incubator 21, thereby improving the convenience of the incubator installation structure.

[0089] The outer ring of the incubator 21 is also provided with multiple mounting ears 27. Multiple support posts extend from the base plate 1. The support posts extend at positions corresponding to the mounting ears 27 on the incubator. The support posts connect the mounting ears 27, supporting the incubator 21 above the base plate 1. Space for the reaction disk power unit 2424 is reserved between the incubator 21 and the base plate 1. Furthermore, the support posts keep the incubator 21 at the same height as the reagent tray 4 and sample tray 3, facilitating the sampling probe's ability to extract samples from the reagent tray and transfer them to the reaction cups.

[0090] A flushing cup 7 is also arranged between the reagent disk 4, the sample disk 3 and the reaction disk 2. The flushing cup 7 corresponds to the position of different sampling needles and is used to flush the sampling needle on the sampling needle after sampling, so as to facilitate the retention of liquid in the sampling needle between two adjacent samplings.

[0091] The sampling needles 5, 61, and 62 are retractable sampling needles with lifting and rotating functions. When extracting liquid between the reagent tray 4, sample tray 3, and reaction tray 2, the swing arm of the sampling needle is higher than the reagent tray 4, sample tray 3, and reaction tray 2. Therefore, when the top cover of the biochemical analyzer is closed, the highest point of the sampling needle will limit the overall height of the instrument after the top cover is installed. By configuring the sampling needles to be retractable in height, the overall height of the top cover is reduced, further reducing the overall volume of the biochemical analyzer during transportation, and improving the ease of transportation of the biochemical analyzer.

[0092] Furthermore, the sampling needle includes a sampling needle seat. A first motor mounting plate is provided on the first side of the sampling needle seat, on which a rotating motor is arranged. A rotating pulley is provided on the second side of the sampling needle seat. The output shaft of the rotating motor is connected to the rotating pulley via a transmission belt, driving the sampling needle to swing to switch the position between the reaction disk and the reagent disk. A push rod is coaxially arranged on the rotating pulley, and the end of the push rod is connected to a swing arm, and the push rod can move up and down along the axis. When the sampling needle is working, the push rod moves the sampling needle to the working height and drives the sampling needle to move up and down during the cleaning process. When the sampling needle completes the liquid extraction work and the biochemical analyzer is folded up and transferred, the sampling needle is automatically retracted, and the sampling needle tip of the sampling needle is recovered into the rinse cup, thereby achieving a reduction in the height of the biochemical analyzer when it is folded up.

[0093] The base 1 is also provided with a flushing needle assembly 8 and a stirring assembly 9 for cleaning the reaction cups on the reaction disk 2 and stirring after adding reagents and samples.

[0094] The foregoing description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Those skilled in the art will readily appreciate that various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention are intended to be within the scope of protection of the present invention.

Claims

1. A 400-speed portable biochemical analyzer, characterized in that: It comprises a base plate, a reaction disk arranged on the base plate, a sample disk and a reagent disk arranged near the reaction disk, a sample sampling needle arranged between the reaction disk and the sample disk, a reagent sampling needle arranged between the reaction disk and the reagent disk, and both the sample sampling needle and the reagent sampling needle have swing arms that can be retracted for storage; The reagent disk, the sample disk and the reaction disk are respectively provided with coaxially driven power devices below.

2. The 400-speed portable biochemical analyzer according to claim 1, characterized in that: The reagent disk has an R1 reagent area and an R2 reagent area which are staggeredly distributed around the circumference thereof, wherein the R1 reagent area is a plurality of concentrically arranged fan-shaped areas, and the fan-shaped areas are used to place the R1 reagent kit; The R2 reagent area includes a plurality of trapezoidal areas arranged between two adjacent sector-shaped areas and arranged along the radial direction of the reagent disk, and the trapezoidal areas are used to place the R2 reagent kit.

3. The 400-speed portable biochemical analyzer according to claim 2, characterized in that: The fan-shaped area is a triangular fan-shaped area with a triangular fan-shaped cross section, and a plurality of the triangular fan-shaped areas form an inner ring structure; The side wall of the trapezoidal region is arranged close to the side wall of the fan-shaped region, and the trapezoidal region is a curved trapezoidal structure in which both the inner wall surface and the outer wall surface are circular arc wall surfaces; The R1 test kit is a fan-shaped test kit that matches the fan-shaped area, and the R2 test kit is a curved trapezoidal test kit that matches the trapezoidal area.

4. The 400-speed portable biochemical analyzer according to claim 3, characterized in that: The R2 reagent areas include four groups that are spaced apart and distributed circumferentially around the reagent disk, and each group of the R2 reagent areas includes two trapezoidal areas; and three sector-shaped areas are arranged between two adjacent R2 reagent areas.

5. The 400-speed portable biochemical analyzer according to claim 1, characterized in that: The reagent disk has a coaxially arranged inner ring reagent area and outer ring reagent area, the inner ring reagent area is the R2 reagent area, and a plurality of R2 reagent kits in a trapezoidal structure are arranged on the R2 reagent area; the outer ring reagent area is the R1 reagent area, and a plurality of R1 reagent kits in a trapezoidal structure are arranged on the R1 reagent area.

6. The 400-speed portable biochemical analyzer according to any one of claims 2 to 5, characterized in that: The reagent disc comprises a reagent kit support and a reagent disc outer cylinder arranged on the reagent kit support, and the R1 reagent area and the R2 reagent area are arranged on the reagent kit support; The substrate is fixed with a reagent disc power device for coaxially driving the reagent kit holder to rotate, the output end of the reagent disc motor is arranged with a reagent kit code disc for monitoring the position of the reagent kit holder, and the substrate is fixed with a reagent kit photoelectric sensor cooperating with the reagent kit code disc.

7. The 400-speed portable biochemical analyzer according to claim 6, characterized in that: The reagent kit support is a plastic reagent kit support, and includes a reagent kit bottom plate connected to the reagent tray motor, and a reagent kit vertical plate extending from the reagent kit bottom plate and used to separate the R1 reagent area from the R2 reagent area.

8. The 400-speed portable biochemical analyzer according to claim 7, characterized in that: The sample tray comprises a sample tube support for arranging sample tubes; a sample tray outer cylinder provided on the substrate for protecting the sample tube support; A sample disk power device coaxially driving the sample tube holder to rotate is fixedly mounted on the base plate, a sample disk code disk for monitoring the position of the sample tube holder is arranged at the output end of the sample disk motor, and a sample disk photoelectric sensor cooperating with the sample disk code disk is fixedly mounted on the base plate.

9. The 400-speed portable biochemical analyzer according to claim 8, characterized in that: The reagent disk power device comprises a first coupling sleeve coaxially arranged with the reagent cartridge support, the first coupling sleeve extending out of the reagent disk outer cylinder has a first linkage gear and a reagent disk motor driving the first linkage gear to rotate; the reagent cartridge code disk is fixedly mounted on the first linkage gear; The sample tray power device comprises a second coupling sleeve coaxially arranged with the sample tube holder, the second coupling sleeve extending out of the lower end of the sample tray outer tube is provided with a second linkage gear and a sample tray motor driving the second linkage gear to rotate; the sample tray code disk is fixedly mounted on the second linkage gear.

10. The 400-speed portable biochemical analyzer according to claim 9, characterized in that: The reaction tray comprises an incubation pot fixedly mounted on the substrate and a reaction cup bracket arranged in the incubation pot and having a disc-shaped structure, wherein a bracket support seat is coaxially arranged in the middle of the reaction cup bracket; A reaction disk power device is arranged at the lower end of the bracket support seat; the reaction disk power device includes a third linkage gear linked to the bracket support seat, and a reaction disk motor driving the third linkage gear to rotate; a reaction device for monitoring the position of the reaction cup bracket is fixed on the third linkage gear. Disk code disk.

11. The 400-speed portable biochemical analyzer according to claim 10, characterized in that: The outer ring of the incubation pot is provided with an annularly arranged incubation track; The reaction cup bracket has an annular outer ring that falls into the incubation track, and the annular outer ring is evenly distributed with a plurality of reaction cup placement holes for placing reaction cups; The middle part of the reaction cup bracket is provided with a rotation driving part connected with the bracket support seat, and the outer periphery of the rotation driving part is connected with the annular outer ring.

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