System and method for cabinet x-ray systems with 3-d optical imaging reconstruction

Abstract

A cabinet x-ray incorporates an x-ray tube, an x-ray detector, and a real-time camera, either High Definition or Standard Resolution, for the production of organic and non-organic images. The computing device receives video data from the real-time camera and the x-ray detector and determines, based on the video data, an overlay of the captured x-ray image with the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). The apparatus captures a real-time image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images with exact orientation of the 2 images.

Description

PATENT APPLICATION forSYSTEM AND METHOD FOR CABINET X-RAY SYSTEMS WITH 3-D OPTICAL IMAGING RECONSTRUCTION BACKGROUNDField of the Present Disclosure;

[0001] The aspects of the disclosed embodiments relate to the field of a cabinet x- ray incorporating a system and method for incorporating an x-ray system and an optical camera, either high definition or standard resolution, taking a real-time image concurrently with the x-ray image / procedure, then displaying and reconstructing the resulting optical mage / s on the system monitor in 3-Dimensions.

[0002] Optical imaging is a powerful tool in biology and the medical field. Optical imaging uses a multi-frequency detector equipped with either a white beam or multi frequency light source to permit the acquisition of images at very low intensity level in a wide wavelength range. Optical imaging as incorporated in a cabinet radiography system allows better orientation and truths to the user. Among the disadvantages of optical methods are the strong scattering and absorption effects in tissue and complexity of light transport, resulting in the absence of a practical, high-resolution 3D image reconstruction algorithm. Here we propose a 3D reconstruction system and method for imaging samplesthat may be organic or inorganic imaged in a cabinet radiography system . We believe our approach is original one and different from other proposed approaches.Background

[0003] Specimen Radiography is considered the most cost-effective screening method for the detection of breast cancer in surgically removed breast tissue. However, the sensitivity of specimen radiography is often limited by the presence of overlapping dense fibroglandular tissue in the breast specimen. Dense parenchyma reduces the conspicuity of abnormalities and thus constitutes one of the main causes of missed breast cancer diagnosis. The advent of full-field digital detectors offers opportunities to develop advanced techniques for improved imaging of dense breasts, such as digital tomosynthesis.

[0004] The photo / captured real-time image may be displayed on the monitor either overlaid onto the resultant x-ray image of the sample or as a Picture-In-a-Picture (PIP) adjacent to the x-ray image of the sample.

[0005] Today, conventional breast specimen systems can gather a digital breast specimen radiogram separately. In these systems, the radiograms of a tissue or bone specimen are viewed separately for analysis.

[0006] With a unit incorporating an optical camera and a system to capture and / or reconstruct the captured image into a 3-D image, the clinician can utilize the resultant phototo expeditiously visualize the specimen excised from the patient to confirm orientation of the excised sample saving time for both the patient on the treatment table and the clinician.

[0007] It would be advantageous in breast procedure rooms to allow the medical professional to operate the cabinet x-ray unit to analyze the excised breast tissue or specimen utilizing the unit to both x-ray and capture an image of the sample for informational and / or diagnostic purposes.

[0008] Embodiments of the current disclosure may alleviate the problems discussed above and / or other problems in the art. The scope of the current disclosure, however, is defined by the attached claims, and not by the ability to solve any specific problem.

[0009] Currently it is believed that there is not a system or method incorporating a real-time camera that can convert or interpret the captured 2-D images into a 3-D image in a cabinet x-ray system.SUMMARY

[0010] In general, this disclosure may enable a device (cabinet x-ray system) utilizing a computer to capture a real-time image of the sample being x-rayed with exact orientation of the 2 images. While cameras incorporated into x-ray cabinets have been around, the particular feature differentiating this invention from previous public domainfeatures is the differentiating factor of attaining the 2 images, X-ray and Optical, in the same and exact orientation and displaying them either PIP or overlaid upon each other.

[0011] A device capturing both an x-ray image and a real-time image of the specimen facilitates confirmation and orientation for the clinician to verify margins are achieved by the professional to the patient.

[0012] In one embodiment, the system would incorporate a laser or multifrequency lights to modulate densities and the computer interpreting and / or constructing a 3-dimensional model of the specimen.

[0013] A preferred embodiment system would incorporate an HD (High- Definition) Camera into a cabinet x-ray unit allowing the system to capture an HD Image and x-ray image of the specimen.

[0014] The embodiment as related above explains how the aspects of the disclosed embodiments would relate to specimen radiography but the aspects of the disclosed embodiments are not isolated to specimen radiography but may be utilized for nondestructive testing, pathology as well as any radiographic analysis, organic and non- organic, requiring a cabinet x-ray system but is not limited to just an HD camera but any camera fitting within the confines of the cabinet x-ray system.

[0015] The aspects of the disclosed embodiments relate to systems, methods, and devices useful for the field of cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a real-time camera for the production of organic and non-organic images. The computing device receives video data from the real-time camera and the x-ray detector anddetermines, based on the video data, an overlay of the captured x-ray image with the captured real-time image or display an adjacent image i.e. Picture-In-Picture (PIP). In particular, the aspects of the disclosed embodiments relate to a system and method with corresponding apparatus for taking a real-time image concurrently with the x-ray image / procedure, then displaying and reconstructing the resulting optical mage / s on the system monitor in 3-D.

[0016] In some embodiments, a scanner is disclosed. The scanner may include a camera coupled to a moving arm. The camera may be configured to move along the rail in a first direction, and the rail may be configured to move with the cart in a second direction different from the first direction. The scanner may also include an imaging device coupled to the cart. The imaging device may be configured to capture a three-dimensional image of a subject. The subject may be an organic or in-organic specimen that fits within the x-ray cabinet, for example.

[0017] In some embodiments, a method of operating a scanner including one or more cameras configured to capture a three-dimensional image of a subject is disclosed. The method may include activating the one or more cameras. The one or more cameras may be coupled to a carriage coupled to an arm. The method may also include moving the carriage along the arm in a first direction, and moving the arm with the carriage in a second direction different from the first direction. In at least some embodiments of the currentdisclosure, the first direction may be transverse, e.g., substantially perpendicular, to the second direction.

[0018] Additionally or alternatively, embodiments of the method may include one or more of the following aspects: the computer system may be further configured to convert the constructed three-dimensional image of the specimen to a modified three- dimensional image, the modified three-dimensional image may be indicative of an expected outcome of a surgical procedure of the excised tissue; the computer system may include a display device to present the constructed three-dimensional image and the modified three-dimensional image; the modified three-dimensional image may represent the expected outcome of a procedure on the excised tissue; the computer system may be configured to receive input from a user and control the first motor and the second motor based on the input; the computer system may be configured to control the first motor and the second motor to move the one or more cameras in a substantially rectangular path; the computer system may be further configured to rotate the one or more cameras about at least one of a first axis extending in the first direction or a second axis extending in the second direction; the computer system may be configured to rotate the one or more cameras about the second axis while the one or more cameras are moving in the first direction.BRIEF DESCRIPTION OF THE DRAWINGS

[0019] To further clarify the above and other advantages and features of the present invention, a more particular description of the invention will be rendered by reference to specific embodiments thereof that are illustrated in the appended drawings. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore notto be considered limiting of its scope. The invention will be described and explained with additional specificity and detail through the use of the accompanying drawings in which:

[0020] FIG. 1 is one example embodiment of the aspects of the disclosed embodiments;

[0021] FIG. 2 is a display of the basic workflow of the one example embodiment;

[0022] FIG. 3 is view in the sample chamber of the example embodiment of the present disclosure;

[0023] FIG. 4 displays an imaging system incorporating aspects of the disclosed embodiments.DETAILED DESCRIPTION

[0024] Reference will now be made to figures wherein like structures will be provided with like reference designations. It is understood that the drawings are diagrammatic and schematic representations of exemplary embodiments of the invention, and are not limiting of the present invention nor are they necessarily drawn to scale. FIGS. 1-3 depict various features of embodiments of the present invention, which embodiments are generally directed to a system that can utilize a real-time camera to capture an image of the specimen / sample concurrently with the acquisition of an x-ray image.

[0025] Referring first to FIG. 1, there is shown an example of the embodiment of a camera incorporated into a Cabinet X-Ray Unit. The medical professional or other authorized operator places a specimen / sample into the chamber, closes and secures thedoor, and presses acquire on the computer screen. Simultaneously the computer commands the camera, x-ray source in conjunction with the x-ray detector to capture images and display them either overlaid or adjacent PIP (Picture-in-Picture) on the monitor. This, in turn, provides more flexibility for a clinician or other user of the system and simplifies the procedure. Manual input for operation of the cabinet x-ray unit may be initiated via keyboard and the resulting image from both the manual-initiated examination is displayed on the screen and configured in accordance with one example embodiment of the present disclosure.

[0026] FIG. 2 displays the basic workflow of the cabinet x-ray unit. FIG. 3 displays the front view into the cabinet x-ray unit. FIG. 4 displays a camera system.

[0027] Currently it is believed that there is not a system or method incorporating a real-time camera in a cabinet x-ray system with exact orientation of the 2 images nor able to reconstruct a 3-dimensional image.

[0028] Indeed, it is appreciated that the system and its individual components can include additional features and components, though not disclosed herein, while still preserving the principles of the present invention. Note also that the base computer can be one of any number devices, including a desktop or laptop computer, etc.

[0029] The aspects of the disclosed embodiments may be embodied in other specific forms without departing from its spirit or essential characteristics. The described embodiments are to be considered in all respects only as illustrative, not restrictive. Allchanges that come within the meaning and range of equivalency of the claims are to be embraced within their scope.

[0030] What is claimed is:

Claims

AMENDED CLAIMS received by the International Bureau on 29 March 2025 (29.03.2025)1. A cabinet x-ray system incorporating a real-time camera, comprising:A. a cabinet x-ray systemB. a computerC. a base unit including an image processor and a display;D. an imaging chain incorporated into the base unit, including: i. x-ray source with x-ray detector; ii. a scanner including the real time camera configured to capture a three dimensional image of a specimen; iii. an interface for enabling an analog / digital signal to be transferred from the real-time camera to the computer.

2. The system as defined in claim 1, in which the real-time camera is configured to supply standard or High-Definition (HD) real-time images.

3. The system of claim 1, in which the cabinet x-ray system concurrently captures an x- ray image and a real-time image concurrently.

4. The system of claim 1 , in which the real-time camera is mounted onto the system whereas to integrate an exact capture / orientation image of the specimen while being x-rayed.

5. The system of claim 1, in which the base unit is enclosed in the cabinet x-ray system.

6. The system of claim 1, in which the base unit is utilized for excised tissue, organ or bone specimens.

7. The system of claim 1, in which the base unit is utilized for any organic or inorganic specimen that fits inside the x-ray cabinet.

8. The system of claim 1 in which the scanner is mounted in the cabinet x-ray system.

9. The system of claim 1 in which the real-time image is displayed overlaid onto the x-ray image or as a Picture-in-Picture - PIP adjacent to the x-ray image.

10. The system of claim 1 in which the cabinet x-ray system incorporates a laser.

11. The system of claim 1 in which the imaging chain is composed of sources emitting at differing frequencies.

12. (Cancelled)STATEMENT UNDER ARTICLE 19 (1 )Applicant respectfully submits that independent claim 1 , as amended, is novel, has inventive step and has industrial applicability.Claim 1 is amended to include a scanner including a real time camera configured to capture a three dimensional image of a specimen, as disclosed in paragraphs [0017]- [0018] and therefore has novelty, has inventive step and has industrial applicability.Claims 2-11 depend from claim 1 , and as a result also are novel, have inventive step and have industrial applicability, by way of their dependencies.

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