Tumor treatment field system, electrode plate, tumor treatment apparatus, and method

Abstract

Provided are a tumor treatment field system, an electrode plate, a tumor treatment apparatus, and a method. The system comprises at least one pair of electrode plates, wherein each of the electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups, grounding terminals of the temperature detection units in each of the row groups are jointly connected to a grounding pin via one control switch, and signal terminals of the temperature detection units in each of the column groups are jointly connected to a switching unit via a single dual-purpose signal cable after being short-circuited to the corresponding electrode units. When the dual-purpose signal cable is connected to a temperature sampling point, an analog temperature signal detected by the corresponding temperature detection unit in each of the row groups is sampled on the basis of the temperature sampling point by configuring the switching state of the control switch; when the dual-purpose signal cable is connected to an alternating power cable, an alternating electric signal is applied to the electrode unit of at least one column group on the basis of the alternating power cable. In this way, the plurality of electrode units can be controlled in a partitioned manner using fewer conductive traces.

Description

Tumor electric field therapy system, electrode sheet, tumor treatment equipment and method Technical Field

[0001] The present application relates to tumor electric field therapy technology, and in particular to a tumor electric field therapy system, electrode sheet, tumor treatment equipment and method. Background Art

[0002] Tumor electric field therapy is a method that uses low-intensity, medium-high frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatment methods, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of microtubules by exerting directional forces on polar particles (such as macromolecules and organelles) in cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] Related art tumor therapy systems use an electric field application device to transmit alternating electrical signals for tumor therapy to electrodes, which then apply an alternating electric field to the patient's tumor site. When the tumor therapy electric field is applied to the patient's body, it accumulates heat at the application site, causing the temperature to rise accordingly. Therefore, the temperature at the application site must be monitored. If the temperature is too high, the electric field intensity must be adjusted promptly to reduce the risk of skin burns caused by excessive heat.

[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which contains multiple electrode units. Even if the same alternating electrical signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field therapy, it is necessary to implement individual control of the over-temperature electrode units. However, for the electrode sheets in the related art, implementing individual control of the electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode sheet. This will increase the number of conductive traces in the electrode sheet substrate, making the electrode sheet less likely to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet.

[0006] Summary of the Invention

[0007] The present application aims to at least partially address one of the technical problems in the related art. To this end, the first objective of the present application is to provide a tumor therapy field system that utilizes fewer conductive traces to control multiple electrode units in a zoned manner, thereby improving the effectiveness of tumor therapy field therapy and facilitating the application of electrode patches.

[0008] The second objective of this application is to provide an electrode sheet.

[0009] The third object of this application is to provide another tumor electric field treatment system.

[0010] The fourth objective of this application is to provide a tumor treatment device.

[0011] The fifth objective of this application is to provide a method for detecting electrode temperature.

[0012] The sixth objective of this application is to provide a method for detecting electrode abnormalities.

[0013] The seventh objective of this application is to provide a control method for a tumor electric field therapy system.

[0014] The eighth objective of this application is to provide a method for identifying electrode sheet types.

[0015] A ninth objective of the present application is to provide a computer-readable storage medium.

[0016] The tenth objective of this application is to provide an adapter for tumor electric field therapy.

[0017] The eleventh objective of this application is to provide an electric field generator for tumor electric field therapy.

[0018] To achieve the above objectives, a first embodiment of the present application provides a tumor electric field therapy system, comprising: at least one pair of electrode sheets, each electrode sheet comprising a plurality of electrode units and a plurality of temperature detection units, each electrode unit being capable of applying an alternating electrical signal, each temperature detection unit being provided corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are arranged into at least two row groups and at least two column groups, the ground terminals of the temperature detection units in each row group being commonly connected to a ground pin via a control switch, and the signal terminals of the temperature detection units in each column group being short-circuited with the corresponding electrode units and then commonly connected to a switching unit via a dual-purpose signal line; the switching unit being configured to switch the dual-purpose signal line between a temperature sampling point and an alternating power line, so that when the dual-purpose signal line is connected to the temperature sampling point, the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point by configuring the switching state of the control switch; and when the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one column group are applied the alternating electrical signal based on the alternating power line.

[0019] According to the tumor electric field therapy system of the embodiment of the present application, for each electrode sheet, multiple electrode units are divided into multiple row groups and multiple column groups, and the ground ends of the temperature detection units corresponding to each electrode unit in each row group are commonly connected to the ground pin through a control switch, and the signal ends of the temperature detection units corresponding to each electrode unit in each column group are respectively short-circuited with the corresponding electrode units and then commonly connected to the switching unit through a dual-purpose signal line; at the same time, the switching unit is configured to switch the dual-purpose signal line to connect to the temperature sampling point or the alternating power line, so that when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point, and when the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one column group are applied with an alternating electric signal based on the alternating power line. In this way, temperature sampling and application of alternating electrical signals can be achieved through the dual-purpose signal line. Not only is no new AC signal line (i.e., AC line) added, but the original AC signal line is also eliminated. Therefore, multiple electrode units can be partitioned and controlled using fewer conductive traces, which not only improves the effect of tumor electric field therapy, but also facilitates the application of electrode sheets.

[0020] Furthermore, the switching unit is also configured to switch the dual-purpose signal line corresponding to each column group to be connected to the corresponding temperature sampling point, so that the analog temperature signal detected by each temperature detection unit in each column group is sampled respectively according to the switching state of the control switch.

[0021] Furthermore, the switching unit is also configured to switch the dual-purpose signal lines corresponding to at least two of the column groups to be connected to the corresponding temperature sampling points at the same time, so that the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the corresponding temperature sampling points according to the switching state of the control switch.

[0022] Furthermore, the switching unit includes at least two bidirectional switches, a first end of each bidirectional switch is connected to the dual-purpose signal line corresponding to each column group, a second end of each bidirectional switch is also connected to the alternating power line, and a third end of each bidirectional switch is connected to the temperature sampling point of the corresponding column group.

[0023] Furthermore, the switching unit is further configured to switch the dual-purpose signal line corresponding to each column group to be connected to the alternating power line, so that the electrode units of each column group are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0024] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the column groups to be connected to the alternating power line at the same time, so that the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0025] Furthermore, the intensity of the alternating electrical signal output by the alternating power line is adjustable.

[0026] Furthermore, the switching unit includes at least two bidirectional switches, a first end of each bidirectional switch is connected to the dual-purpose signal line corresponding to each column group, a second end of each bidirectional switch is connected to a different alternating power line, and a third end of each bidirectional switch is connected to the temperature sampling point of the corresponding column group.

[0027] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two column groups to connect to different alternating power lines, so that each electrode unit of each column group is applied with the alternating electrical signal based on a different alternating power line.

[0028] Furthermore, the strength of the alternating electrical signals output by different alternating power lines can be adjusted respectively.

[0029] Furthermore, each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

[0030] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0031] Furthermore, an adapter is included, wherein the control switch, the switching unit and the voltage dividing resistor are respectively arranged in the adapter.

[0032] Furthermore, the adapter includes a first controller and an ADC unit, the ADC unit is connected to each of the temperature sampling points to sample the analog temperature signal through each of the temperature sampling points, and the first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

[0033] Furthermore, the first controller is also configured to configure the switch state of the control switch.

[0034] Furthermore, the first controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0035] Furthermore, it also includes an electric field generator, which is configured to output the alternating electric signal through the alternating power line.

[0036] Furthermore, the electric field generator includes a second controller and an AC signal generator, the second controller is connected to the AC signal generator, and the second controller is configured to control the AC signal generator to adjust the intensity of the alternating electric signal output by the alternating power line.

[0037] Furthermore, the electric field generator is further configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

[0038] Furthermore, the electric field generator also includes a power switch, which is arranged between the AC signal generator and the switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

[0039] Furthermore, the second controller is also configured to configure the switch state of the control switch.

[0040] Furthermore, the second controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0041] To achieve the above-mentioned purpose, the second embodiment of the present application provides an electrode sheet for use in a tumor electric field therapy system, wherein the tumor electric field therapy system includes a switching unit, and the electrode sheet includes: a substrate; a plurality of electrode units and a plurality of temperature detection units arranged on the substrate, each of the electrode units being capable of applying an alternating electrical signal, and each of the temperature detection units being arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups; the ground terminals of the temperature detection units in each row group are connected to a ground pin in common through a control switch; each of the column groups After the signal ends of the temperature detection units are short-circuited with the corresponding electrode units, they are connected to the switching unit through a dual-purpose signal line, so that the dual-purpose signal line is switched by the switching unit to be connected to the temperature sampling point or the alternating power line; when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to the electrode unit of at least one column group based on the alternating power line.

[0042] Furthermore, when the dual-purpose signal lines corresponding to each column group are connected to corresponding temperature sampling points respectively, the analog temperature signals detected by the temperature detection units in each column group are sampled respectively by configuring the switch state of the control switch.

[0043] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to corresponding temperature sampling points, the switching state of the control switch is configured so that the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the corresponding temperature sampling points respectively.

[0044] Furthermore, in a case where the dual-purpose signal lines corresponding to each column group are respectively connected to the alternating power line, the electrode units of each column group are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0045] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the alternating power line, the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0046] Furthermore, the intensity of the alternating electrical signal output by the alternating power line is adjustable.

[0047] Furthermore, in a case where the dual-purpose signal lines corresponding to the at least two column groups are connected to different alternating power lines, the alternating electrical signals are applied to the electrode units of each column group based on different alternating power lines.

[0048] Furthermore, the strength of the alternating electrical signals output by different alternating power lines can be adjusted respectively.

[0049] Furthermore, each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

[0050] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0051] Furthermore, each of the electrode units is provided with a through-hole, and the through-hole is suitable for accommodating the temperature detection unit.

[0052] Furthermore, the plurality of electrode units and the plurality of temperature detection units are arranged in a substantially array in terms of spatial arrangement, and are arranged in a plurality of rows and columns in terms of circuit connection.

[0053] Furthermore, the number of the plurality of electrode units and the number of the plurality of temperature detection units are both 20, and they are arranged in four rows and five columns in terms of circuit connection.

[0054] To achieve the above-mentioned purpose, the third aspect of the present application provides a tumor electric field therapy system, comprising: at least one pair of the aforementioned electrode sheets; an electric field generator, the electric field generator being used to generate an alternating power supply and transmit the alternating power supply to each of the electrode sheets through the alternating power supply line; a control unit, the control unit being used to configure at least one of the switching state of the control switch and the switching state of the switching unit, so as to sample the analog temperature signal detected by the corresponding temperature detection unit in each of the row groups based on the corresponding temperature sampling point, or to control the electrode units of at least one of the column groups to be applied with the alternating electric signal based on the alternating power supply line.

[0055] To achieve the above-mentioned objectives, the fourth embodiment of the present application provides a tumor treatment device, including: the aforementioned tumor electric field treatment system.

[0056] To achieve the above-mentioned purpose, the fifth aspect of the present application provides an electrode sheet temperature detection method, which is applied to the aforementioned tumor electric field therapy system or the aforementioned tumor electric field therapy system. The method includes: controlling the switching unit so that the dual-purpose signal line corresponding to at least one of the column groups in the corresponding electrode sheet is connected to the corresponding temperature sampling point; controlling the control switch corresponding to each of the row groups so as to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0057] Furthermore, when the dual-purpose signal lines corresponding to each column group are respectively connected to the corresponding temperature sampling points, the control switches corresponding to each row group are controlled, including: controlling the control switches corresponding to each row group to close in sequence to respectively sample the analog temperature signals of each electrode unit in each column group.

[0058] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the corresponding temperature sampling points, the control switch corresponding to each of the row groups is controlled, including: controlling the control switch corresponding to each of the row groups to close in sequence to respectively sample the analog temperature signals of the corresponding electrode units in each of the row groups.

[0059] To achieve the above-mentioned purpose, the sixth aspect of the present application provides an electrode sheet abnormality detection method, wherein a preset threshold is preset in the adapter or the electric field generator, and the method includes: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and judging whether the electrode sheet has an abnormality based on the temperature detection signal.

[0060] Furthermore, judging whether the electrode sheet is abnormal according to the temperature detection signal includes: if it is determined according to the temperature detection signal that any electrode unit in the corresponding electrode sheet is abnormal or faulty, judging that the electrode sheet is unqualified.

[0061] Furthermore, determining whether the electrode sheet is abnormal is based on the temperature detection signal, including: when it is determined based on the temperature detection signal that there are abnormal or faulty electrode units in the corresponding electrode sheet, determining the number of abnormal or faulty electrode units; when the number of abnormal or faulty electrode units reaches a preset threshold, determining that the electrode sheet needs to be replaced.

[0062] Furthermore, judging whether the electrode sheet is abnormal based on the temperature detection signal includes: comparing the temperature of each electrode unit in the corresponding electrode sheet with a preset temperature threshold based on the temperature detection signal; and judging whether the temperature of the electrode sheet is abnormal based on the comparison result.

[0063] Furthermore, judging whether the temperature of the electrode sheet is abnormal based on the comparison result includes: determining that the temperature of the electrode sheet is abnormal when the temperature of any electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold.

[0064] To achieve the above-mentioned purpose, the seventh embodiment of the present application provides a control method for a tumor electric field therapy system, wherein the adapter or the electric field generator is preset with a preset temperature threshold, a preset quantity threshold, a first preset temperature and a second preset temperature, and the method includes: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and controlling the intensity of the alternating electric signal applied to the electrode unit according to the temperature detection signal.

[0065] Furthermore, the intensity of the alternating electric signal applied to the electrode unit is controlled according to the temperature detection signal, including: comparing the temperature of each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; and controlling the intensity of the alternating electric signal according to the comparison result.

[0066] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature of at least one electrode unit exceeds a preset temperature threshold, stopping applying the alternating electric signal to the electrode unit of the electrode sheet.

[0067] Furthermore, stopping applying the alternating electric signal to the electrode units of the electrode sheet includes: stopping applying the alternating electric signal to all electrode units of the electrode sheet; or stopping applying the alternating electric signal to all electrode units in the column group where the electrode units in the electrode sheet that exceed a preset temperature threshold are located.

[0068] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: determining the number of over-temperature column groups when the temperature at at least one electrode unit exceeds a preset temperature threshold; stopping applying the alternating electric signal to all electrode units of the electrode sheet when the number of over-temperature column groups exceeds a preset number threshold; and stopping applying the alternating electric signal to all electrode units in the column group where the electrode unit exceeding the preset temperature threshold is located in the electrode sheet when the number of over-temperature column groups does not exceed the preset number threshold.

[0069] Furthermore, when the application of the alternating electric signal to all electrode units in the column group where the electrode unit exceeding the preset temperature threshold in the electrode sheet is located is stopped, the method further includes: continuing to apply the alternating electric signal to the electrode units in other column groups in the electrode sheet.

[0070] Furthermore, the intensity of the alternating electric signal applied to the electrode units of other column groups in the electrode sheet is adjustable.

[0071] Furthermore, the intensity of the alternating electric signal applied to the electrode units of each column group in the other column groups is adjustable.

[0072] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature at all electrode units in the electrode sheet does not exceed the preset temperature threshold, if the temperature at all electrode units in the electrode sheet does not exceed the first preset temperature, then increasing the intensity of the alternating electric signal applied to the electrode units of the electrode sheet, wherein the first preset temperature is less than the preset temperature threshold.

[0073] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: if the temperature at at least one electrode unit in the electrode sheet exceeds the first preset temperature and is less than the preset temperature threshold, then the alternating electric signal strength currently applied to the electrode unit of the electrode sheet is maintained unchanged.

[0074] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: if the temperature at at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than the preset temperature threshold, reducing the intensity of the alternating electric signal applied to the electrode unit of the electrode sheet, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0075] Furthermore, when the number of the over-temperature column groups does not exceed the preset number threshold, the method also includes: if the temperature at each electrode unit in the non-over-temperature column group does not exceed the first preset temperature, increasing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0076] Furthermore, when the number of the over-temperature column groups does not exceed the preset number threshold, the method also includes: if the temperature of at least one electrode unit in the non-over-temperature column group exceeds the first preset temperature and is less than the preset temperature threshold, then the alternating electric signal strength currently applied to the electrode unit of the non-over-temperature column group is maintained unchanged.

[0077] Furthermore, when the number of the over-temperature column groups does not exceed the preset number threshold, the method also includes: if the temperature of at least one electrode unit in the non-over-temperature column group exceeds a second preset temperature and is less than a preset temperature threshold, then reducing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature column group, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0078] Furthermore, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0079] Furthermore, the increasing extents of the electric field intensities corresponding to the column groups whose alternating electric signal intensities are increased are different from each other.

[0080] Furthermore, maintaining the strength of the alternating electrical signal currently applied to the electrode unit unchanged includes: maintaining the strength of the alternating electrical signal currently applied to the first target column group unchanged, wherein the first target column group is a column group where the temperature at the electrode unit exceeds a first preset temperature and is less than a preset temperature threshold.

[0081] Furthermore, reducing the intensity of the alternating electrical signal applied to the electrode unit includes: reducing the intensity of the alternating electrical signal applied to the electrode unit of a second target column group, wherein the second target column group is a column group having an electrode unit at which the temperature exceeds a second preset temperature and is less than a preset temperature threshold.

[0082] To achieve the above-mentioned purpose, the eighth embodiment of the present application provides an electrode sheet type identification method, which includes: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and identifying the type of the electrode sheet based on the temperature detection signal.

[0083] To achieve the above-mentioned purpose, the ninth embodiment of the present application provides a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0084] To achieve the above-mentioned purpose, the tenth embodiment of the present application provides an adapter for tumor electric field therapy, including a first memory and a first controller, wherein the first memory stores a computer program, and when the computer program is executed by the first controller, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0085] To achieve the above-mentioned purpose, the eleventh embodiment of the present application provides an electric field generator for tumor electric field therapy, including a second memory and a second controller, wherein the second memory stores a computer program, and when the computer program is executed by the second controller, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0086] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0087] FIG1 is a schematic diagram of a tumor treating field system according to an embodiment of the present application;

[0088] FIG2 is a schematic diagram of the structure of the electrode sheet of the tumor electric field treatment system shown in FIG1;

[0089] FIG3 is a schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor treating field system shown in FIG1 ;

[0090] FIG4 is similar to FIG3 , which is another circuit connection diagram of an electrode sheet and an adapter shown in FIG3 ;

[0091] FIG5 is a schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of the tumor electric field treating system shown in FIG1 ;

[0092] FIG6 is a schematic block diagram of the internal structure of the adapter of the tumor therapeutic field system shown in FIG1 ;

[0093] FIG7 is a schematic block diagram of the internal structure of an electric field generator of the tumor treating field system shown in FIG1 ;

[0094] FIG8 is a flow chart of a method for detecting electrode temperature according to an embodiment of the present application;

[0095] FIG9 is a flow chart of a method for detecting abnormality of an electrode sheet according to an embodiment of the present application;

[0096] FIG10 is a flow chart of a control method of a tumor treating field system according to an embodiment of the present application;

[0097] FIG11 is a schematic flow chart of a method for identifying electrode sheet types according to an embodiment of the present application;

[0098] FIG12 is a flow chart of a signal control method for tumor therapeutic field therapy according to an embodiment of the present application;

[0099] FIG13 is a flow chart of a method for detecting electrode temperature according to another embodiment of the present application;

[0100] FIG14 is a flow chart of a method for applying an alternating electric signal for tumor electric field therapy according to another embodiment of the present application;

[0101] FIG15 is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to an embodiment of the present application;

[0102] FIG16 is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to another embodiment of the present application.

[0103] FIG17 is a schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0104] FIG18 is a schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of a tumor electric field treating system according to another embodiment of the present application;

[0105] FIG19 is a schematic block diagram of the internal structure of the adapter of the tumor therapeutic field system shown in FIG18;

[0106] FIG20 is a schematic block diagram of the internal structure of the electric field generator of the tumor treating field system shown in FIG18;

[0107] FIG21 is a flow chart of a control method of a tumor treating field system according to another embodiment of the present application;

[0108] FIG22 is a flow chart of a signal control method for tumor therapeutic field therapy according to another embodiment of the present application;

[0109] Description of reference numerals:

[0110] Tumor electric field therapy system 100 or 100', electrode sheet 13 or 13', first cable 15 or 15', adapter 20 or 20', second cable 25 or 25', electric field generator 30 or 30', substrate 31 or 31', electrode unit 33 or 33', temperature detection unit 35 or 35', ground terminal 35-1 or 35-1', signal terminal 35-2 or 35-2', temperature sensor 34 or 34', ground terminal 34-1 or 34-1', signal terminal 34-2 or 34-2', electrode unit 33 or 33', diode 36 or 36', Anode 36-1 or 36-1', cathode 36-2 or 36-2', second power supply module 32 or 32', second controller 37 or 37', second communication unit 38 or 38', AC signal generator 39 or 39', power switch 40 or 40', first controller 51 or 51', ADC unit 52 or 52', voltage divider resistor 53 or 53', control switch 54 or 54', first control switch 54-1 or 54-1', second control switch 54-2 or 54-2', third control switch 54-3 or 54-3', fourth control switch 54- 4 or 54-4', a two-way switch 55 or 55', a first two-way switch 55-1 or 55-1', a second two-way switch 55-2 or 55-2', a third two-way switch 55-3 or 55-3', a fourth two-way switch 55-4 or 55-4', a fifth two-way switch 55-5 or 55-5', a first communication unit 56 or 56', an alternating power line 57 or 57', a first power module 58 or 58', a ground line 18 or 18', a first ground line 18-1 or 18-1', and a second ground line 18-2 or 18-2' , third ground line 18-3 or 18-3', fourth ground line 18-4 or 18-4', dual-purpose signal line 19 or 19', first dual-purpose signal line 19-1 or 19-1', second dual-purpose signal line 19-2 or 19-2', third dual-purpose signal line 19-3 or 19-3', fourth dual-purpose signal line 19-4 or 19-4', fifth dual-purpose signal line 19-5 or 19-5', first connector 60 or 60', first plug 61, first socket 62, second connector 70 or 70', second plug 71 or 71', second socket 72 or 72'. DETAILED DESCRIPTION

[0111] The following embodiments of the technical solution of the present application will be described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application and are therefore only examples and are not intended to limit the scope of protection of the present application.

[0112] Example 1:

[0113] FIG1 is a schematic diagram of a tumor electric field therapy system 100 according to an embodiment of the present application. As shown in FIG1 , the tumor electric field therapy system 100 includes: at least one pair of electrode sheets 13, an adapter 20 connected to the at least one pair of electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode sheets 13 can be arranged in pairs on the patient's body surface, such as the four electrode sheets 13 in FIG1 , where each two electrode sheets 13 are arranged as a pair on the patient's body surface. The electric field generator 30 is used to supply power to the at least one pair of electrode sheets 13 so that the at least one pair of electrode sheets 13 generates an alternating electric field for treating tumors. The adapter 20 is electrically connected between the at least one pair of electrode sheets 13 and the electric field generator 30, and is used to transmit the alternating electric signal generated by the electric field generator 30 to the at least one pair of electrode sheets 13. That is to say, the electric field generator 30 is capable of generating an alternating electric signal, and the generated alternating electric signal is transmitted to each electrode sheet 13 through the adapter 20, so that an alternating electric field for treating tumors is generated between the same pair of electrode sheets 13, so as to apply an alternating electric field to the patient's tumor site for tumor treatment.

[0114] As shown in FIG1 , in this embodiment, there are four electrode sheets 13 , each of which includes an equal number of electrode units 33 . Each electrode unit 33 is electrically connected to the adapter 20 , and the number of electrode units 33 on each electrode sheet 13 is 20. In other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode sheets 13 ; in other embodiments, each pair of electrode sheets 13 may have the same number of electrode units 33 , while different pairs of electrode sheets 13 may have different numbers of electrode units 33 ; in still other embodiments, the number of electrode units 33 on each electrode sheet 13 may be 9, 13, etc.

[0115] Figures 3 and 4 are schematic diagrams of the circuit connection between the electrode sheet 13 and the adapter 20 in two operating states of the tumor electric field therapy system 100 shown in Figure 1. It is important to note that the arrangement of the electrode units 33 shown in Figures 3 and 4 is intended to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. The arrangement of the electrode units 33 shown in Figures 3 and 4 does not represent the spatial arrangement of the electrode units 33. Referring to Figures 1, 3, and 4, the electrode sheet 13 includes a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 35, and a first cable 15 electrically connected to the substrate 31. The substrate 31 can be a flexible printed circuit board. Multiple conductive traces are embedded within the substrate 31, including multiple grounding wires 18 and multiplexed signal wires 19. The first cable 15 has multiple conductors (not shown), each of which is electrically connected to the multiple grounding wires 18 and multiplexed signal wires 19 of the substrate 31. In this embodiment, the total number of grounding wires 18 and dual-purpose signal wires 19 embedded in the substrate 31 does not exceed 10, and thus the number of conductors of the first cable 15 does not exceed 10.

[0116] The multiple electrode units 33 are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13 is provided with 20 electrode units 33. The 20 electrode units 33 are arranged in the order of 1 to 20 for circuit connection, and are divided into four row groups and five column groups. That is, the 20 electrode units 33 are arranged in four rows and five columns for circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode units 33 and temperature detection units 35 are both soldered to the substrate 31, and the electrode units 33 are short-circuited with the signal terminal 35-2 of the corresponding temperature detection unit 35. Since the multiple temperature detection units 35 are arranged in a one-to-one correspondence with the multiple electrode units 33, the multiple temperature detection units 35 are also arranged in four rows and five columns for circuit connection. It should be noted that the arrangement here is to more clearly illustrate the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode units 33 in the spatial structure. Its spatial structure may be a roughly array structure as shown in Figure 2, or it may be other structures, such as petal-shaped or scattered, and it may be regular or irregular. The electrode unit 33 is configured to apply an alternating electric field to the patient's tumor site. The temperature detection unit 35 is configured to detect the temperature of the patient's body surface to which the electrode sheet 13 is applied, that is, the temperature at the corresponding electrode unit 33, and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the substrate 31 are respectively arranged in a one-to-one correspondence with the multiple column groups of the electrode units 33, and are configured to transmit the alternating electric signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding column group. That is, the electrode units 33 in the same column group are short-circuited via the same dual-purpose signal line 19 on the substrate 31, while the electrode units 33 in different column groups are connected in parallel via different dual-purpose signal lines 19 on the substrate 31. The dual-purpose signal line 19 on the substrate 31 is electrically connected to the first cable 15 and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 on the substrate 31 receives the alternating electrical signal generated by the electric field generator 30 via the first cable 15 and the adapter 20.

[0117] Each electrode unit 33 of the electrode sheet 13 has three operating modes. In the first mode, the electrode unit 33 applies an AC signal via the dielectric element 35. In the second mode, the temperature sensor 34 detects or collects the temperature of the patient's body surface to which the corresponding electrode unit 33 is applied. In the third mode, the application of the AC signal and the temperature detection and collection are stopped. The first, second, and third modes do not overlap in time. That is, the time periods during which the dielectric element 35 of the electrode unit 33 applies the AC signal are staggered and do not overlap with the time periods during which the temperature sensor 34 detects the temperature. The electrode unit 33 can cyclically switch between applying the AC signal via its dielectric element 35 and detecting the temperature via its temperature sensor 34, that is, the electrode unit 33 can cyclically switch between the first and second modes. The electrode unit 33 can also cyclically switch between the first, second, and third modes, that is, the electrode unit 33 cyclically switches between applying the AC signal via the dielectric element 35, collecting or detecting the temperature via the temperature sensor 34, and then cessation of applying the AC signal and continuing to collect the temperature.

[0118] Multiple grounding lines 18 are provided in a one-to-one correspondence with the multiple row groups of electrode units 33. These lines are used to sequentially short-circuit each temperature detection unit 35 in each row group to ground. Specifically, the ground terminals 35-1 of each of the temperature detection units 35 in the same row group are short-circuited via the same grounding line 18 on the substrate 31. The ground terminals 35-1 of each of the temperature detection units 35 in different row groups are connected in parallel via different grounding lines 18 on the substrate 31. During the temperature detection period, only one of the multiple grounding lines 18 is conductive at any given time; the other three are disconnected.

[0119] Each of the multiplexed dual-purpose signal lines 19 is further configured to short-circuit the signal terminal 35-2 of at most one temperature detection unit 35 in each row group to an external device for receiving detection signals. Each of the multiplexed dual-purpose signal lines 19 is connected to a different signal terminal 35-2 of each temperature detection unit 35 to prevent the dual-purpose signal line 19 from subsequently outputting duplicate signals. Specifically, when the number of electrode units 33 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 35-2 of a different temperature detection unit 35 in the row group. When the number of electrode units 33 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 35-2 of a temperature detection unit 35, and each of the remaining dual-purpose signal lines 19 is electrically connected to the signal terminal 35-2 of a different temperature detection unit 35 in the row group. In this embodiment, the external device for receiving detection signals is an adapter 20. The signal ends 35 - 2 of the temperature detection units 35 in different column groups are connected in parallel via different dual-purpose signal lines 19 of the substrate 31 , and the signal ends 35 - 2 of the temperature detection units 35 in the same column group are short-circuited to the same dual-purpose signal line 19 of the substrate 31 .

[0120] In this embodiment, each electrode unit 33 is equipped with a temperature detection unit 35 for temperature detection. The aforementioned circuit design reduces the number of conductors in the first cable 15, preventing cable thickness and stiffness that would increase the difficulty of securing the cable. Furthermore, the increased number of conductors in the first cable 15 prevents the adhesion between the electrode sheet 13 and the patient's body surface corresponding to the tumor site. The base plate 31 includes nine grounding wires 18 and two dual-purpose signal wires 19. Specifically, in this embodiment, the base plate 31 includes four grounding wires 18 and five dual-purpose signal wires 19. The number of grounding wires 18 is related to the number M of rows of electrode units 33, which is greater than or equal to the number of rows of electrode units 33, where M is a positive integer. The number of dual-purpose signal wires 19 is related to the number N of columns of electrode units 33, which is greater than or equal to the number of columns of electrode units 33, where N is a positive integer. The number of circuits L embedded in the base plate 31 of the electrode sheet 13 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal wires 19. In this embodiment, the number of the ground lines 18 is equal to the number M of the row groups of the electrode units 33 ; and the number N of the dual-purpose signal lines 19 is equal to the number N of the column groups of the electrode units 33 .

[0121] The plurality of electrode units 33 are arranged on the substrate 31 in a roughly two-dimensional array, spaced apart. As shown in FIG2 , the electrode sheet 13 in this embodiment includes 20 electrode units 33 and 20 temperature detection units 35 corresponding to the electrode units 33. The 20 electrode units 33 are arranged in an array of four rows and six columns. The first and fourth rows each contain four electrode units 33, and the second and third rows each contain six electrode units 33. The four electrode units 33 in each row of the first and fourth rows are located in each of the second to fifth columns, and the six electrode units 33 in each row of the second and third rows are located in each of the first to sixth columns. The four electrode units 33 in the first row are divided into region 1, the electrode units 33 in the first column of the second row, the first column of the third row, and the second and third columns of the fourth row are divided into region 2, the electrode units 33 in the sixth column of the second row, the sixth column of the third row, and the fourth and fifth columns of the fourth row are divided into region 3, the electrode units 33 in the second and third columns of the second row, and the second and third columns of the third row are divided into region 4, and the electrode units 33 in the fourth and fifth columns of the second row, and the fourth and fifth columns of the third row are divided into region 5. Each region (1-5) corresponds to a column group. In other embodiments, the 20 electrode units 33 can also be arranged in other ways. Of course, in other embodiments, the electrode sheet 13 can also have other numbers of electrode units 33. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0122] Each electrode unit 33 can apply an alternating electric signal, and the electrode sheets 13 configured in pairs are used to apply an alternating electric field to the patient's tumor site. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer composed of a polymer material. Each temperature detection unit 35 is provided corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be provided at any position of the corresponding electrode unit 33. In this embodiment, each electrode unit 33 is provided with a through-hole 331, and the through-hole 331 is suitable for installing the temperature detection unit 35. For example, the middle part of each electrode unit 33 has a through-hole 331, and the through-hole 331 of each electrode unit 33 accommodates a corresponding temperature detection unit 35. Each temperature detection unit 35 includes a temperature sensor 34 and a diode 36. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1. The diode 36 has an anode 36-1 and a cathode 36-2. The anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34. The cathode 36-2 of the diode 36 serves as the ground terminal 35-1 of the temperature detection unit 35. The signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensor other than a thermistor. Each temperature sensor 34 corresponds to a diode 36. The diode 36 is connected in series with the temperature sensor 34 of the same electrode unit 33. The diode 36 can prevent reverse current flow, thereby preventing the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0123] As shown in FIG3 or FIG4 , the electrode sheet 13 of this embodiment includes four grounding wires 18, each of which is used to ground the ground terminals 35-1 of the temperature detection units 35 in the same row group. The four grounding wires 18 of the electrode sheet 13 are respectively a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. Of the four row groups of the electrode sheet 13, the first row group consists of electrode units 33-1 to 33-5, the second row group consists of electrode units 33-6 to 33-10, the third row group consists of electrode units 33-11 to 33-15, and the fourth row group consists of electrode units 33-16 to 33-20. Specifically, the first grounding line 18-1 is used to ground the electrode units 33-1 to 33-5 in the first row group; the second grounding line 18-2 is used to ground the electrode units 33-6 to 33-10 in the second row group; the third grounding line 18-3 is used to ground the electrode units 33-11 to 33-15 in the third row group; and the fourth grounding line 18-4 is used to ground the electrode units 33-16 to 33-20 in the fourth row group. It should be noted that these grounding lines 18 can be selectively closed or opened. This can be achieved by connecting each grounding line 18 in series with a control switch 54. That is, the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33 in each row group are connected to the ground pin through a control switch 54. This will be described in detail below. The aforementioned "grounding the electrode units 33" may refer to grounding the ground terminal 34-1 of the temperature sensor 34 corresponding to each electrode unit 33, or may refer to connecting the diode 36 in series with the temperature sensor 34 corresponding to the same electrode unit 33 and grounding them together. In short, each grounding wire 18 short-circuits the ground terminals 35-1 of the temperature detection units 35 corresponding to all the electrode units 33 in each row group and grounds them.

[0124] As shown in FIG3 or FIG4 , the electrode sheet 13 of this embodiment further includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 33 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating electrical signals. In other words, for each row group, each dual-purpose signal line 19 can selectively connect to one of the electrode units 33 or not connect to any of the electrode units 33 in that row group, thereby preventing the dual-purpose signal lines 19 from subsequently outputting duplicate signals. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the four electrode units 33, namely, electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16, and the signal end 35-2 of the temperature detection unit 35 corresponding thereto; one end of the second dual-purpose signal line 19-2 is connected to the four electrode units 33, namely, electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17, and the signal end 35-2 of the temperature detection unit 35 corresponding thereto; one end of the third dual-purpose signal line 19-3 is connected to the four electrode units 33, namely, electrode unit 33-3, electrode unit 33-8, and electrode unit 33 The fourth dual-purpose signal line 19-4 is connected to the four electrode units 33 (electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19) and the signal terminals 35-2 of the temperature detection units 35 respectively. The fifth dual-purpose signal line 19-5 is connected to the four electrode units 33 (electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20) and the signal terminals 35-2 of the temperature detection units 35 respectively. In short, each dual-purpose signal line 19 parallel-circuits the electrode units 33 and the signal terminals 35-2 of the temperature detection units 35 respectively in the same column group and is used for connection to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 55 and coordinating the closing or opening of the ground line 18.That is, after the signal ends 35-2 of each temperature detection unit 35 in each column group are short-circuited with the corresponding electrode unit 35, they are connected to a switching unit (unnumbered) through a dual-purpose signal line 19. The switching unit (unnumbered) includes a plurality of bidirectional switches 55, which are configured to switch the dual-purpose signal line 19 to connect to the temperature sampling point (unnumbered) or the alternating power line 57, so that when the dual-purpose signal line 19 is connected to the temperature sampling point (unnumbered), the switching state of the control switch 54 is configured to enable the temperature detection signal detected by the corresponding temperature detection unit 35 in each row group to be sampled based on the temperature sampling point (unnumbered), and when the dual-purpose signal line 19 is connected to the alternating power line 57, an alternating electrical signal is applied to the electrode unit 33 of at least one column group based on the alternating power line 57. The details will be described in detail below.

[0125] The multiple ground lines 18 and the multiplexed signal lines 19 are conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multiple ground lines 18 and the multiplexed signal lines 19 embedded in the substrate 31 are electrically connected to corresponding wires (not shown) in the first cable 15.

[0126] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the aforementioned electrode sheets 13, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides alternating electrical signals to the multiple electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or is used to receive temperature detection signals output by the temperature detection units 35 corresponding to the multiple electrode units 33. The adapter 20 transmits the alternating electrical signals generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13, and is also configured to receive the temperature detection signals output by the multiplexed dual-purpose signal line 19 of the electrode sheet 13.

[0127] 3 and 4 , the adapter 20 includes a first controller 51, multiple ADC units 52 connected to the first controller 51, multiple sets of voltage dividers 53 and control switches 54 corresponding to the multiple ADC units 52, multiple sets of bidirectional switches 55 corresponding to the multiple ADC units 52, a first communication unit 56, an alternating current line 57 connected to each set of bidirectional switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple ADC units 52. The first power module 58 provides a DC power supply VCC to the electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered), which are electrically connected to multiple ground lines 18 and multiplexed signal lines 19 within the substrate 31 of the corresponding electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (unnumbered) include multiple alternating power lines 57 that transmit alternating electrical signals to corresponding electrode sheets 13 and are electrically connected to the multiplexed signal lines 19 within the substrate 31 of the corresponding electrode sheet 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19 within the substrate 31 of the corresponding electrode sheet 13 and are used to supply power to each temperature detection unit 35 of the electrode sheet 13 or transmit the temperature detection signal of the electrode sheet 13, and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18 within the substrate 31 of the corresponding electrode sheet 13. The number L of circuit lines electrically connected to one electrode sheet 13 by the adapter 20 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode sheet 13; the number H of circuit lines electrically connected to X electrode sheets 13 by the adapter 20 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13, that is, H = XL = X*(M+N). The number of control switch groups 54 and the number of bidirectional switch groups 55 are both related to the number of electrode sheets 13. The number of control switch groups 54 is the same as the number of bidirectional switch groups 55, and is not less than the number of electrode sheets 13. Optionally, the number of control switch groups 54 and the number of bidirectional switch groups 55 are both the same as the number of electrode sheets 13. The following is a detailed description of the electrical connection between an electrode sheet 13 having 20 electrode units 33 and the adapter 20 as an example.

[0128] Each group of control switches 54 is provided with a plurality of control switches 54, and the plurality of control switches 54 are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding one by one to the multi-way grounding lines 18 of the corresponding electrode sheet 13, and are configured to control the conduction or disconnection of the multi-way grounding lines 18. The circuit lines (not numbered) that are electrically connected one by one to the multi-way grounding lines 18 of the electrode sheet 13 are grounded at one end close to the control switches 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding lines 18 of the substrate 31 of the corresponding electrode sheet 13, and the two are equal in this embodiment. As shown in Figure 3 or Figure 4, in this embodiment, the plurality of control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3 and a fourth control switch 54-4. The plurality of control switches 54 in the same group all control the closing or disconnection of the corresponding grounding line 18 of the same electrode sheet 13 one by one. The first control switch 54-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 13, and further can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 in the first row group 33 of the electrode sheet 13; the second control switch 54-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 13, and further can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 in the second row group 33 of the electrode sheet 13; The third control switch 54-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 13, and can then cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 in the third row group 33 of the electrode sheet 13; the fourth control switch 54-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 13, and can then cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 in the fourth row group 33 of the electrode sheet 13. The above-mentioned control switch 54 can be a mechanical switch, such as a relay. The control switch 54 can also be an electronic switch, and each control switch 54 can be opened and closed by an additional first controller 51.

[0129] In this embodiment, the multiple groups of control switches 54 are all electronic switches. The first controller 51 is in communication with the multiple groups of control switches 54 and is used to sequentially and cyclically control the on / off states of the multiple control switches 54 in each group of control switches 54, thereby sequentially and individually connecting each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and coordinating the switching of the corresponding bidirectional switch 55 to collect the patient's body surface temperature detected by all temperature detection units 35 on the electrode sheet 13. The number of control switches 54 in each group is no less than the number of grounding wires 18 on the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of control switches 54 in each group is the same as the number of grounding wires 18 of the corresponding electrode sheet 13.

[0130] Each set of bidirectional switches 55 includes a plurality of bidirectional switches 55. The plurality of bidirectional switches 55 in each set are connected to the adapter 20 and are electrically connected to circuit lines (not numbered) corresponding one-to-one to the multiplexed signal lines 19 of a corresponding electrode sheet 13. The number of bidirectional switches 55 in each set of bidirectional switches 55 is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, and is greater than or equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of bidirectional switches 55 in each set of bidirectional switches 55 is equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13. Each bidirectional switch 55 has a signal acquisition terminal 1 marked as 1 and a signal input terminal 2 marked as 2. The signal acquisition terminals 1 of multiple bidirectional switches 55 in the same group are electrically connected one by one to corresponding detection channels of multiple detection channels of a corresponding group of ADC units 52 through temperature sampling points (unnumbered). The signal input terminals 2 of each bidirectional switch 55 in the same group are electrically connected to the corresponding same alternating power line 57, and are configured to control the multi-channel dual-purpose signal line 19 to connect to the corresponding alternating power line 57 to transmit the alternating electrical signal or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0131] As shown in Figures 3 and 4 , taking the electrical connection between one electrode sheet 13 and the adapter 20 as an example, in this embodiment having 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3, a fourth bidirectional switch 55-4, and a fifth bidirectional switch 55-5. The plurality of bidirectional switches 55 in the same group each control the switching between transmitting an alternating electrical signal and transmitting a temperature detection signal on a corresponding one of the multiplexed signal lines 19 of the same electrode sheet 13. Specifically, the first bidirectional switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13 between transmitting the alternating electrical signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 in the first column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 in the first column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the first column of electrode units 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 transmit the alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. signal; the second bidirectional switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the second column electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 transmit the alternating electric signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52;The third bidirectional switch 55-3 is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 in the third column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit corresponding to the electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 in the third column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the third column of electrode units 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 transmit the alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52; The fourth bidirectional switch 55-4 is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 in the fourth column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 in the fourth column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the fourth column of electrode units 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 transmits the alternating electrical signal to the patient or outputs the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the ADC unit 52;The fifth bidirectional switching switch 55-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode sheet 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 in the fifth column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 in the fifth column group and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the fifth column electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 transmits alternating electrical signals to the patient or outputs the temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. When the signal input terminal 2 of each set of bidirectional switches 55 is on and the signal acquisition terminal 1 is off, it can transmit an alternating electrical signal to each electrode unit 33 of the corresponding electrode sheet 13. When the signal acquisition terminal 1 of each set of bidirectional switches 55 is on and the signal input terminal 2 is off, it can cooperate with each control switch 54 in the corresponding set of control switches 54 to transmit the temperature detection signal collected by the temperature detection unit 35 of each electrode element 33 on the electrode sheet 13 in a time-sharing manner. The bidirectional switches 55 can be mechanical switches, such as relays. Alternatively, they can be electronic switches, and each bidirectional switch 55 can be switched by an additional first controller 51.

[0132] In this embodiment, the plurality of sets of bidirectional switches 55 are all electronic switches. The first controller 51 is in communication with the plurality of sets of bidirectional switches 55 and is configured to control the plurality of bidirectional switches 55 in each set of bidirectional switches 55 to switch between their respective signal acquisition terminals 1 and signal input terminals 2, and to coordinate the closing or opening of the corresponding control switches 54 to continuously monitor the patient's body surface temperature detected by all temperature detection units 35 on the electrode sheet 13 or to transmit an alternating electrical signal to the patient.

[0133] In this embodiment, each group of ADC units 52 is electrically connected to the signal acquisition terminals 1 of the plurality of bidirectional switches 55 in the corresponding group of bidirectional switches 55 via a multi-channel circuit line (not numbered) within the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital signal. Each group of ADC units 52 includes a plurality of detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding one of the multiplexed signal lines 19 via the corresponding bidirectional switch 55. As shown in Figures 3 and 4, each group of ADC units 52 includes a total of five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the signal acquisition terminal 1 of the first bidirectional switch 55-1. The second detection channel B is connected to the second dual-purpose signal line 19-2 via the signal acquisition terminal 1 of the second bidirectional switch 55-2. The third detection channel C is connected to the third dual-purpose signal line 19-3 via the signal acquisition terminal 1 of the third bidirectional switch 55-3. The fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the signal acquisition terminal 1 of the fourth bidirectional switch 55-4. The fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the signal acquisition terminal 1 of the fifth bidirectional switch 55-5. Each detection channel A, B, C, D, and E is configured to receive a temperature detection signal collected by the temperature detection unit 35 corresponding to the electrode unit 33 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 58 via a corresponding voltage divider resistor 53 within the adapter 20, which is used to provide a detection voltage to the detection channel A, B, C, D, and E. The first power supply module 58 provides direct current power.

[0134] In this embodiment, the first communication unit 56 is configured to acquire the digital signals output by the multiple sets of ADC units 52 and transmit the digital signals to the electric field generator 30. The electric field generator 30 is further configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33 of the electrode sheet 13 based on the received digital signals. For example, when any of the multiple digital signals received exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds a preset temperature threshold (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30 can be appropriately reduced to prevent the electrode units 33 of the electrode sheet 13 from overheating when the alternating electrical signal is applied, thereby preventing low-temperature burns on the patient's skin. The above-mentioned preset temperature threshold and preset threshold can be determined based on human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital signals converted by the multiple sets of ADC units 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C-45°C.

[0135] 5 and 6 , in this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, the multiple ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is provided between each electrode sheet 13 and the adapter 20. The first connector 60 is adapted to connect the corresponding electrode sheet 13 to the adapter 20. As shown in FIG1 , the first connector 60 includes a first plug 61 provided at an end of the first cable 15 away from the electrode sheet 13 and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, i.e., the first connector 60 connects the adapter 20 to the electrode sheet 13 in the manner of a connector. Each first cable 15 has five wires electrically connected one-to-one to the two-way switches 55 in the corresponding group of two-way switches 55 and four wires electrically connected one-to-one to the control switches 54 in the corresponding group of control switches 54. That is, each first connector 60 is electrically connected one-to-one to a corresponding group of two-way switches 55 and a corresponding group of control switches 54 of the adapter 20 through nine wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0136] A second connector 70 is provided between the adapter 20 and the electric field generator 30. The second connector 70 is adapted to connect the electric field generator 30 to the adapter 20. As shown in FIG1 , the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, meaning that the second connector 70 connects the adapter 20 to the electric field generator 30 using a connector-type design. Each first connector 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 via a corresponding alternating power line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54 and a corresponding set of ADC units 52. Each first connector 60 is connected to the second connector 70 and a corresponding set of ADC units 52 via a corresponding set of bidirectional switches 55. The second cable 25 has eight conductors, including four conductors 1 to 4 electrically connected to corresponding alternating power lines 57 for transmitting alternating electrical signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data transmitting line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. A second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and is grounded. The VCC pin of the second connector 70 is also connected to the corresponding set of voltage dividers 53 and the corresponding set of ADC units 52 via the VCC power line of the first power module 58.

[0137] Referring to Figures 5 and 7 , the electric field generator 30 includes a second power module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power module 32, and the GND pin of the second connector 70 is grounded via the GND line of the second power module 32. The second power module 32 is also connected to and powered by the second controller 37 and the AC signal generator 39. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 via its data receive line RX and to the wire 6 of the second connector 70 via its data transmit line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the set of power switches 40 and adjust the relevant parameters of the alternating electrical signal applied by the AC signal generator 39 based on the relevant digital signals received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the wires 1 to 4 of the second connector 70 that transmit the alternating electrical signal through the set of power switches 40. The set of power switches 40 includes a plurality of power switches 40, and the plurality of power switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each power switch 40 is electrically connected to a corresponding wire 1, 2, 3, 4 in the second connector 70 that transmits the alternating electrical signal through an AC power line 41-1, 41-2, 41-3, 41-4, and is electrically connected to the corresponding electrode sheet 13 through the corresponding wire 1, 2, 3, 4 of the second connector 70, so as to transmit the alternating electrical signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the set of power switches 40 via multiple AC power lines 41. Specifically, the number of power switches 40 in the electric field generator 30 is related to the number of electrode pads 13. In this embodiment, the number of power switches 40 is equal to the number of electrode pads 13, and both are four. The power switches 40 include a first power switch 40-1, a second power switch 40-2, a third power switch 40-3, and a fourth power switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 in a one-to-one correspondence.One end of the first power switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 1 for transmitting the alternating electric signal in the second connection 70 through an AC power line 41-1, and is electrically connected to the alternating power line 57 at the port X1 of the adapter 20 through the conductor 1 of the second connector 70, the alternating power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20 One end of the second power supply switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 2 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-2 and electrically connected to the alternating power line 57 at the port Y1 of the adapter 20 through the conductor 2 of the second connector 70, the alternating power line 57 at the port Y1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20 One end of the third power switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 3 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-3 and electrically connected to the alternating power line 57 at the port X2 of the adapter 20 through the conductor 3 of the second connector 70, the alternating power line 57 at the port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20 One end of the fourth power supply switch 40-4 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-4 and electrically connected to the alternating power line 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the alternating power line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13 to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0138] The working principle of the tumor electric field treating system 100 of this embodiment will be described in detail below with reference to FIG. 3 to FIG. 5 .

[0139] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal acquisition end 1 of each of the multiple bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal input end 2 to be turned off, so as to disconnect the alternating electric signal applied to the electrode sheet 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the control switches 54 in a group of control switches 54 electrically connected to the electrode sheet 13 to be turned on in sequence and in a time-sharing manner. At this time, the temperature detection signals collected by each temperature detection unit 35 corresponding to each electrode unit 33 of each row group of the electrode sheet 13 can be collected in a time-sharing manner and in a sequence through multiple detection channels A, B, C, D, and E of a group of ADC units 52 corresponding to the electrode sheet 13. Each detection channel A, B, C, D, and E of each group of ADC units 52 only collects the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 of the same row group of the electrode sheet 13 at the same time. The above-mentioned temperature detection signals can be represented by voltage values. Among the four control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13, only one control switch 54 can be turned on at the same time, and the other three are turned off. All five bidirectional switches 55 in a group of bidirectional switches 55 corresponding to the group of ADC units 52 are switched to their respective signal acquisition terminals 1 so that the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding ADC units 52 in a one-to-one correspondence and turned on. With this arrangement, the group of ADC units 52 can collect the voltage values ​​of all temperature detection units 35 corresponding to the electrode units 33 in the same row group that are short-circuited with the ground line 18 corresponding to the turned-on control switch 54.

[0140] Specifically, when the control switch 54-1 is closed, the control switches 54-2, 54-3, and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-1 to 33-5 of the first row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-6 to 33-20 of the remaining row groups are powered off, and the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, 33-11, and 33-16 of the first detection channel A of the ADC unit 52 of the group are short-circuited. As for the signal terminal 35-2 of the detection unit 35, since only the signal terminal 35-2 of the temperature detection unit 35 corresponding to electrode unit 33-1 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-6, 33-11, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-1 will not be affected. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-1 is effectively operating on the first detection channel A of the group of ADC units 52. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-1. Similarly, the voltage value collected by the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-2. The voltage value collected by the third detection channel C in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-3. The voltage value collected by the fourth detection channel D in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-4. The voltage value collected by the fifth detection channel E in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-5.

[0141] When the control switch 54-2 is closed, the control switches 54-1, 54-3, and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-6 to 33-10 of the second row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-5 and the electrode units 33-11 to 33-20 of the remaining row groups are powered off, and the electrode units 33-1, 33-6, 33-11, and 33-16 on the first detection channel A of the ADC unit 52 of this group are short-circuited. The signal terminals 35-2 of the corresponding temperature detection units 35 are connected to the ground because only the ground terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-6 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-1, electrode units 33-11, and electrode units 33-16 are disconnected. Moreover, each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34. Therefore, the resistance value of the temperature detection unit 35 corresponding to electrode unit 33-6 is not affected. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-6 is effectively operating on the first detection channel A of the group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-6. Similarly, the voltage value collected by the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-7. The voltage value collected on the third detection channel C in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-8. The voltage value collected on the fourth detection channel D in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-9. The voltage value collected on the fifth detection channel E in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-10.

[0142] When the control switch 54-3 is closed, the control switches 54-1, 54-2 and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4 and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-11 to 33-15 of the third row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-10 and the electrode units 33-16 to 33-20 of the remaining row groups are powered off, and the electrode units 33-1, 33-6, 33-11 and 33-16 on the first detection channel A of the group of ADC units 52 are short-circuited. Since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-11 is connected to ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to electrode units 33-1, 33-6, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, the resistance of the temperature detection unit 35 corresponding to electrode unit 33-11 will not be affected. Therefore, only the temperature detection unit 35 corresponding to electrode unit 33-11 is effectively operating on the first detection channel A of the set of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-11. Similarly, the voltage value collected by the second detection channel B of the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-12. The voltage value collected by the third detection channel C in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-13. The voltage value collected by the fourth detection channel D in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-14. The voltage value collected by the fifth detection channel E in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-15.

[0143] When the control switch 54-4 is closed, the control switches 54-1, 54-2, and 54-3 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-16 to 33-20 of the fourth row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-15 of the remaining row groups are powered off, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-15 of the first detection channel A of the ADC unit 52 of this group are short-circuited. 5, since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-16 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, and 33-11 are all disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, it will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-16. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-16 is effectively operating on the first detection channel A of the group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-16. Similarly, the voltage value collected by the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-17. The voltage value collected by the third detection channel C in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-18. The voltage value collected by the fourth detection channel D in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-19. The voltage value collected by the fifth detection channel E in the set of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-20.

[0144] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of a certain electrode sheet 13 by controlling a set of bidirectional switching switches 55 and a set of control switches 54 that are electrically connected to the electrode sheet 13. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be connected to the corresponding temperature sampling points (unnumbered) at the same time, and by configuring the switching states of the corresponding control switches 54, the temperature detection signals detected by the corresponding temperature detection units 35 in each row group are sampled based on the corresponding temperature sampling points (unnumbered). Similarly, the temperature detection signals of the temperature detection units 35 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0145] The first controller 51 or the second controller 37, the plurality of ADC units 52 and the plurality of bidirectional switches 55 can automatically perform operations according to pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls all the bidirectional switches 55 in the corresponding group of bidirectional switches 55 to switch to the signal acquisition terminal 1 so that the signal acquisition terminals 1 of the bidirectional switches 55 are all turned on and the signal input terminals 2 are all turned off so that the dual-purpose signal lines 19 of the corresponding electrode sheets 13 are electrically connected to the corresponding group of ADC units 52. Then, the control switch 54-1 in the corresponding group of control switches 54 is closed and the remaining control switches 54-2 to 54-4 in the group of control switches 54 are turned off. During this period, the group Each detection channel A, B, C, D, and E of the ADC unit 52 obtains the temperature detection signals of each temperature detection unit 35 corresponding to each electrode unit 33 in the first row group of the corresponding electrode sheet 13, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset interval, the first controller 51 or the second controller 37 closes the control switch 54-2 in the group of control switches 54 and opens the control switches 54-1, 54-3, and 54-4 in the group of control switches 54. During this period, each detection channel A, B, C, D, and E of the ADC unit 52 obtains the temperature detection signals of each temperature detection unit 35 corresponding to each electrode unit 33 in the second row group. By sequentially turning on each control switch 54 in the group of control switches 54, the temperature detection signals of all temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature detection units 35 on at least one pair of electrode sheets 13 can be obtained.

[0146] It should be noted that, in other embodiments, a group of bidirectional switches 55 and a group of control switches 54 electrically connected to a certain electrode sheet 13 can also be controlled by the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 to realize the collection of temperature detection signals of the temperature detection units 35 corresponding to some electrode units 33 of the electrode sheet 13 in the same temperature collection time period. For example, when only the first bidirectional switch 55-1 is switched to its signal collection terminal 1, the switch 54-1 can be controlled to be closed first, and the control switches 54-2, 54-3 and 54-4 can be disconnected. At this time, only the temperature detection units 35 corresponding to the electrode units 33-1 of the first row group are energized, and the signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the group of ADC units 52. Therefore, the group of ADC units 52 will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1; then, the control switch 54-2 is controlled to be closed, and the control switches 54-1, 54-3 and 54-4 are controlled to be closed. 3 and control switch 54-4 are all open. At this time, the ADC unit 52 in this group will detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-6. Then, control switch 54-3 is closed, and control switches 54-1, 54-2, and 54-4 are all open. At this time, the ADC unit 52 in this group will detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-11. Finally, control switch 54-4 is closed, and control switches 54-1, 54-2, and 54-3 are all open. At this time, the ADC unit 52 in this group will detect the voltage value of the temperature detection unit 35 corresponding to electrode unit 33-16. Thus, within the same acquisition time period, only the temperature detection signals of the temperature detection units 35 corresponding to one column group of electrode units 33 can be sampled. Similarly, the temperature detection signals of the temperature detection units 35 corresponding to other column groups of electrode units 33 can be sampled within other acquisition time periods. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal line 19 corresponding to each column group to the corresponding temperature sampling point (unnumbered), and by configuring the on / off state of the control switch 54, the temperature detection signal detected by each temperature detection unit 35 in each column group is sampled separately. It should be noted that in other embodiments, the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 of two, three, or four column groups can also be sampled within the same sampling time period, which will not be further described here.

[0147] Specifically, when an alternating electric signal needs to be applied to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input terminal 2 of each of the multiple bidirectional switches 55 in a group of bidirectional switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal acquisition terminal 1 to be turned off, and controls a power switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 via the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be connected to the alternating power line 57 at the same time, so that the electrode units 33 of at least two column groups are simultaneously applied with alternating electric signals based on the alternating power line 57.

[0148] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switches 55 electrically connected to a certain electrode sheet 13 to apply alternating electrical signals to some electrode units 33 of the electrode sheet 13 in the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input terminal 2 of the first bidirectional switch 55-1 among the multiple bidirectional switches 55 in the group of bidirectional switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal acquisition terminal 1 to be turned off, and controls a power switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply alternating electrical signals to the first column group of electrode units 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 of the electrode sheet 13 through the AC power line 57, and the voltage or current of the applied alternating electrical signals is adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal line 19 corresponding to each column group to be connected to the alternating power line 57, so that the electrode units 33 of each column group are simultaneously applied with an alternating electrical signal based on the alternating power line 57. It should be noted that in other embodiments, the alternating electrical signal can also be applied to the electrode units 33 of two, three, or four column groups simultaneously within the same time period, which will not be further described in detail here.

[0149] It should be noted that in the embodiment of the present application, the control switch 54 electrically connected to each of the multiple grounding lines 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode sheet 13 are both provided in the adapter 20. However, in other embodiments, the control switch 54 electrically connected to the grounding line 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal line 19 may also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the ADC unit 52 provided in the adapter 20 may also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0150] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or increasing the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35 obtained; or identify the type of the electrode sheet based on the obtained temperature detection signal if the electrode sheet is qualified; or determine whether the electrode unit 33 of the electrode sheet 13 is overheated based on the obtained temperature detection signal if the electrode sheet is qualified, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode units 33 of the corresponding column of the electrode sheet 13 to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 13. In addition, the substrate 31 of the electrode sheet 13 of the present application is electrically connected to the same electrode unit 33 and the signal end 35-2 of the corresponding temperature detection unit 35 through the same dual-purpose signal line 19. While it can transmit both alternating electrical signals and direct current signals for temperature signal acquisition and the collected temperature detection signals through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid thereon, reducing the wiring difficulty of the substrate 31, simplifying the manufacturing process, reducing the weight of the substrate 31, and reducing manufacturing costs. The electrode sheet 13 of the present application can also switch between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the collected temperature detection signals through the combined control of a control switch 54 electrically connected to the grounding line 18 laid thereon and a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0151] Specifically, when it is necessary to apply an alternating electric signal to the patient through the electrode units 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls all the control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13 to be disconnected, and at the same time controls all the bidirectional switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to be switched to their respective signal input terminals 2, so that the signal acquisition terminals 1 of the bidirectional switching switches 55 are all disconnected and the signal input terminals 2 are all turned on, so that the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to the adapter 20 and an alternating power line 57 corresponding to the electrode sheet 13, thereby transmitting the alternating electric signal to the electrode units 33 of the electrode sheet 13.When the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of the electrode sheet 13 are detected to be much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through a corresponding alternating power line 57 of the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; when the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of the electrode sheet 13 are detected to be lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39 through the second controller 37, Thereby reducing the voltage or current of the alternating electric signal applied to the pair of electrode sheets 13; when it is detected that the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than the preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to be disconnected through the second controller 37 to stop applying the alternating electric signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to switch from their signal input end 2 to the signal acquisition end 1, that is, controlling all the bidirectional switching signal acquisition ends 1 of a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and all the signal input ends 2 to be disconnected, thereby stopping applying the alternating electric signal to the electrode sheet 13; or, when it is detected that the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than the preset temperature threshold When the temperature of the electrode sheet 13 is lowered to the preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls a bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its signal input end 2 to its signal acquisition end 1, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 simultaneously controls the remaining bidirectional switches 55 electrically connected to the electrode units 33 of the electrode sheet 13 whose temperature detection signals do not exceed the preset temperature threshold and are in different columns from the electrode units 33 whose temperature detection signals exceed the preset temperature threshold to continue to maintain electrical connection with their respective signal input ends 2, so as to stop applying alternating electric signals to all electrode units 33 in the column where the electrode unit 33 whose temperature detection signals of the electrode sheet 13 exceed the preset temperature threshold is located, and continue to apply alternating electric signals to the electrode units 33 in the remaining columns whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold.Thus, the alternating electric signal application control method based on the temperature detection signal of the tumor electric field therapy system 100 is realized.

[0152] The present embodiment provides an electrode sheet temperature detection method, which is applied to the electrode sheet 13 or the tumor electric field therapy system 100 described above, and as shown in FIG8 , includes the following steps:

[0153] Step 210 : Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0154] Specifically, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 and at the same time connect the direct current signal of the signal end 35-2 of the temperature detection unit 35 applied to each electrode unit 33 of the electrode sheet 13.

[0155] Further, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch from one end electrically connected to the alternating electrical signal to one end electrically connected to the direct electrical signal, that is, the bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch from its signal input end 2 to its signal acquisition end 1; or, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch the electrode unit 33 of each electrode unit 33 of the electrode sheet 13 from the on state to the off state, and at the same time, the signal end 35-2 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 is switched from the off state to the on state.

[0156] Step 220: Control the control switch 54 corresponding to each row group to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0157] Specifically, the control switch 54 electrically connected to the ground terminal 35 - 1 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 is turned on in a time-sequential manner to obtain the temperature detection signal of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 .

[0158] In some embodiments, when the dual-purpose signal lines 19 corresponding to each column group are respectively connected to the corresponding temperature sampling points, the control switches 54 corresponding to each row group are controlled, including: controlling the control switches 54 corresponding to each row group to close in sequence to respectively sample the analog temperature signals of each electrode unit 33 in each column group.

[0159] In other embodiments, when the dual-purpose signal lines 19 corresponding to at least two column groups are simultaneously connected to the corresponding temperature sampling points, the control switch 54 corresponding to each row group is controlled, including: controlling the control switch 54 corresponding to each row group to close in sequence to respectively sample the analog temperature signals of the corresponding electrode units 33 in each row group.

[0160] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and based on the obtained temperature detection signals of all temperature detection units of the electrode sheet, it can be judged whether the temperature detection units of the electrode sheet are faulty, whether there is an abnormality, whether the electrode sheet is qualified, or whether it needs to be replaced; it can also be judged whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature detection units of the electrode sheet when each temperature detection unit of the electrode sheet is normal, and then the alternating electric signal applied to the electrode sheet or applied to each electrode unit of the electrode sheet can be controlled; it can also be used to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature detection unit of the electrode sheet.

[0161] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature, and the second preset temperature is lower than the preset temperature threshold.

[0162] 9 , the present application also provides a method for detecting abnormal electrode temperature, which includes the following steps:

[0163] Step 210 : Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0164] Step 220 : Control the control switches 54 corresponding to each row group to sample the analog temperature signals of the corresponding electrode units 33 based on the corresponding temperature sampling points to determine the temperature detection signals of the respective electrode units 33 in each electrode sheet 13 .

[0165] Step 230: Determine whether the electrode sheet 13 is abnormal based on the temperature detection signal.

[0166] In some embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0167] Step 231: Compare the temperature of each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold according to the temperature detection signal. Specifically, the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0168] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison result. Specifically, determine whether the temperature of each electrode unit 33 in the electrode sheet 13 is abnormal based on the comparison result.

[0169] The comparison results in step 232 include not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C-42°C. Optionally, the preset temperature threshold is 40.5°C-41.5°C. Optionally, the preset temperature threshold is 41°C-41.5°C. Optionally, the preset temperature threshold is 41°C.

[0170] The process of determining whether the temperature of the electrode sheet 13 is abnormal based on the comparison result in step 232 is as follows: if the temperature of any electrode unit 33 in the corresponding electrode sheet 13 exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. If the temperature of all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0171] In other embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0172] Step 233: When it is determined according to the temperature detection signal that any one of the electrode units 33 in the corresponding electrode sheet 13 is abnormal or faulty, the electrode sheet 13 is determined to be unqualified.

[0173] Specifically, based on the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed. Then, based on whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed, it is determined whether the electrode sheet 13 is qualified. When the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed, the electrode sheet 13 is determined to be unqualified. When the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 do not have any abnormality or have not failed, the electrode sheet 13 is determined to be qualified.

[0174] In some other embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0175] Step 234 : When it is determined based on the temperature detection signal that an abnormal or faulty electrode unit 33 exists in the corresponding electrode sheet 13 , the number of the abnormal or faulty electrode units 33 is determined.

[0176] Step 235: When the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0177] Specifically, based on the temperature detection signals obtained from the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13; and then, based on whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0178] For example, when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or faulty, and the number of abnormal or faulty temperature detection units 35 exceeds a preset threshold, the electrode sheet 13 is determined to need to be replaced. When the number of abnormal or faulty temperature detection units 35 in the electrode sheet 13 does not exceed the preset threshold, the electrode sheet 13 is determined not to need to be replaced. The preset threshold is 20% of the total number of all temperature detection units 35 in the electrode sheet 13.

[0179] 10 , the present application also provides a method for controlling a tumor therapeutic field system, which includes the following steps:

[0180] Step 210 : Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0181] Step 220 : Control the control switches 54 corresponding to each row group to sample the analog temperature signals of the corresponding electrode units 33 based on the corresponding temperature sampling points to determine the temperature detection signals of the respective electrode units 33 in each electrode sheet 13 .

[0182] Step 240: Control the intensity of the alternating electric signal applied to the electrode unit 33 according to the temperature detection signal.

[0183] Specifically, when it is determined that the electrode sheet 13 does not need to be replaced, the alternating electrical signal applied to each electrode unit 33 in the electrode sheet 13 is controlled or adjusted based on the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13. In other words, steps 234-235 can be added between steps 240 and 220.

[0184] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal in step 240 specifically includes the following steps:

[0185] Step 241 : Compare the temperature of each electrode unit 33 in the electrode sheet 13 with a preset temperature threshold according to the temperature detection signal.

[0186] Step 242: Control the intensity of the alternating electric signal according to the comparison result.

[0187] In some embodiments, controlling the strength of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0188] Step 2421: If the temperature of at least one electrode unit 33 exceeds a preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33 of the electrode sheet 13. Specifically, when the temperature detection signals obtained from all electrode units 33 of the electrode sheet 13 show a temperature detection signal exceeding the preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33 of the electrode sheet 13. If the temperature detection signals obtained from all electrode units 33 of the electrode sheet 13 do not exceed the preset temperature threshold, continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13.

[0189] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13 in step 2421 specifically includes: stopping applying the alternating electric signal to all electrode units 33 of the electrode sheet 13; or stopping applying the alternating electric signal to all electrode units 33 in the column group of the electrode unit 33 in the electrode sheet 13 that exceeds a preset temperature threshold.

[0190] Furthermore, while the application of the alternating electrical signal to all electrode cells 33 in the column group containing the electrode cell 33 in the electrode sheet 13 that has exceeded the preset temperature threshold is stopped, the alternating electrical signal continues to be applied to the electrode cells 33 in other column groups in the electrode sheet 13. The intensity of the alternating electrical signal applied to the electrode cells 33 in other column groups in the electrode sheet 13 is adjustable. For example, the alternating electrical signal continues to be applied to all electrode cells 33 in the electrode sheet 13 whose temperature detection signals have not exceeded the preset temperature threshold and are in a different column from the electrode cell 33 whose temperature detection signals have exceeded the preset temperature threshold, and the intensity of the alternating electrical signal is adjustable.

[0191] In other embodiments, controlling the strength of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0192] Step 2422: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0193] In step 2422 , the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase magnitude.

[0194] Step 2423: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength currently applied to the electrode unit 33 of the electrode sheet 13 is maintained unchanged.

[0195] Step 2424: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the electrode sheet 13 is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0196] In step 2424 , the electric field strength corresponding to each column group whose alternating electric signal strength is reduced has the same reduction amplitude.

[0197] Exemplarily, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature detection signal approaches the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0198] In some other embodiments, controlling the intensity of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0199] Step 2425: When the temperature of at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature column groups.

[0200] Step 2426 : When the number of over-temperature column groups exceeds a preset threshold, stop applying the alternating electrical signal to all electrode units 33 of the electrode sheet 13 .

[0201] Step 2427 : When the number of over-temperature column groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 in the column group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located.

[0202] Furthermore, while stopping the application of the alternating electrical signal to all electrode cells 33 in the column group containing the electrode cell 33 that exceeds the preset temperature threshold in the electrode sheet 13, the alternating electrical signal continues to be applied to the electrode cells 33 in other column groups in the electrode sheet 13. The intensity of the alternating electrical signal applied to the electrode cells 33 in other column groups in the electrode sheet 13 is adjustable.

[0203] Step 2428: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature at each electrode unit 33 in the non-over-temperature column group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0204] In step 2428, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase magnitude.

[0205] Step 2429: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature column group exceeds the first preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit 33 of the non-over-temperature column group remains unchanged.

[0206] Step 2430: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature column group exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature column group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0207] In step 2430 , the electric field strength corresponding to each column group whose alternating electric signal strength is reduced has the same reduction amplitude.

[0208] Exemplarily, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature detection signal approaches the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0209] 11 , the present application also provides a method for identifying electrode sheet types, which includes the following steps:

[0210] Step 210 : Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0211] Step 220 : Control the control switches 54 corresponding to each row group to sample the analog temperature signals of the corresponding electrode units 33 based on the corresponding temperature sampling points to determine the temperature detection signals of the respective electrode units 33 in each electrode sheet 13 .

[0212] Step 250: Identify the type of the electrode sheet 13 according to the temperature detection signal.

[0213] Specifically, when the electrode sheet 13 is qualified or there is no abnormality or failure in each temperature detection unit 35 of the electrode sheet 13, the type of the electrode sheet 13 is identified based on the temperature detection signal detected by the temperature detection unit 35 of each electrode unit 33 in the electrode sheet 13.

[0214] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13. The method includes: combining and controlling the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode sheet 13 so that each electrode unit 33 of the electrode sheet 13 switches between applying an alternating electric signal and collecting a temperature detection signal.

[0215] 12 , the present application further provides a signal control method for tumor electric field therapy, which is used for the electrode sheet 13 . The method includes:

[0216] Step 310: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and executing step 320;

[0217] Step 320 : Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect temperature detection signals of the electrode units 33 of the electrode sheet 13 in rows and executing step 330 ;

[0218] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signal and execute step 340;

[0219] Step 340 : Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the control switch 54 and the bidirectional switch 55 .

[0220] The operating state of each electrode unit 33 of the electrode sheet 13 in step 340 includes at least one of: stopping applying the alternating electrical signal and continuing to collect the temperature detection signal; and stopping collecting the temperature detection signal and continuing to apply the alternating electrical signal. Continuing to apply the alternating electrical signal includes continuing to apply the alternating electrical signal by increasing the voltage or current amplitude of the currently applied alternating electrical signal, continuing to apply the alternating electrical signal by maintaining the voltage or current amplitude of the currently applied alternating electrical signal unchanged, or continuing to apply the alternating electrical signal by reducing the voltage or current amplitude of the currently applied alternating electrical signal.

[0221] The operating state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal it collects. Each electrode unit 33 of the electrode sheet 13 is divided into different regions. Each electrode unit 33 in each region is controlled by a combination of a control switch 54 and a bidirectional switch 55 to cyclically switch between applying an alternating electrical signal and collecting a temperature detection signal.

[0222] The present embodiment provides another method for detecting the temperature of an electrode sheet for a tumor electric field therapy system 100. As shown in FIG13 , the temperature detection method includes:

[0223] Step 510: disconnect the input of the alternating electrical signal of the electrode sheet 13, perform combination control on the multiple control switches 54 and the multiple bidirectional switches 55, and obtain the temperature detection signal of the temperature sensor 34 of the electrode sheet 13 corresponding to each combination in all combinations;

[0224] Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 34 in the electrode sheet 13 to obtain a digital temperature signal;

[0225] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signal.

[0226] In step 510, the combined control of the plurality of control switches 54 and the plurality of bidirectional switches 55 specifically includes:

[0227] Step 511: placing all bidirectional switches 55 at the signal acquisition terminal 1 to conduct electrical connections between the signal terminals 35 - 2 of the temperature detection units 35 corresponding to all electrode units 33 and the corresponding ADC units 52 ;

[0228] Step 512: Sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner to collect the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the corresponding row group row by row.

[0229] In step 512 , sequentially and time-sharingly closing one of the plurality of control switches 54 can connect the detection channels electrically connected between the ADC unit 52 and each temperature detection unit 35 in the row group corresponding to the closed control switch 54 .

[0230] In this way, the temperature detection signals of the corresponding temperature detection units 35 in each row group can be obtained in turn, and then after processing by the adapter 20 or the electric field generator 30, the corresponding temperatures of all electrode units 33 on the electrode sheet 13 can be obtained, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0231] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 33 can also be detected as needed. The specific process of the method for performing temperature detection on a certain electrode unit 33 of the electrode sheet 13 is as follows: disconnect the input of the alternating electric signal, place the bidirectional switch 55 corresponding to the column group where the electrode unit 33 that needs to be individually measured is located at the signal acquisition terminal 1, and place the remaining bidirectional switches 55 at the signal input terminal 2; at the same time, turn on and ground the control switch 54 corresponding to the row group where the electrode unit 33 that needs to be individually measured is located, and turn off all the remaining control switches 54. In this way, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33. For example, if the electrode unit 33 that needs to be individually measured is electrode unit 33-1, then the bidirectional switch 55-1 corresponding to electrode unit 33-1 is set to signal acquisition terminal 1, and the remaining bidirectional switches (55-2 to 55-5) are all set to signal input terminal 2. At the same time, the control switch 18-1 corresponding to electrode unit 33-1 is closed and grounded, and the remaining control switches (18-2 to 18-4) are all opened. In this way, the temperature of electrode unit 33-1 can be detected.

[0232] The present application also provides another method for applying an alternating electric signal for tumor treating field therapy, which is applied to the above-mentioned tumor treating field therapy system 100. As shown in FIG. 14 , the alternating electric signal application method includes:

[0233] Step 610: Determine the region (1-5) where the electrode unit 33 to which the alternating electrical signal needs to be applied is located in the electrode sheet 13;

[0234] Step 611: Combining and controlling a plurality of control switches 54 and a plurality of bidirectional switches 55 electrically connected to the electrode sheet 13 to apply an alternating electrical signal.

[0235] In step 611, the combination of controlling the plurality of control switches 54 and the plurality of bidirectional switches 55 electrically connected to the electrode sheet 13 is specifically as follows:

[0236] Step 612: Disconnect all control switches 54 electrically connected to the electrode sheet 13;

[0237] Step 613: Determine the column groups where the electrode units 33 in the areas where the alternating electric signals need to be applied are located according to the areas where the electrode units 33 in the areas where the alternating electric signals need to be applied are located;

[0238] Step 614: determining the bidirectional switches 55 electrically connected to the electrode units 33 in the column groups according to the column groups where the electrode units 33 to which the alternating electrical signals are applied are located;

[0239] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be applied so that the electrode unit 33 to which the alternating electric signal needs to be applied is electrically connected to the alternating power line 57 to apply the alternating electric signal; at the same time, control the remaining bidirectional switching switches 55 so that the electrical connection between each electrode unit 33 in the area where the alternating electric signal does not need to be applied and the alternating power line 57 is disconnected to stop applying the alternating electric signal.

[0240] In step 615, "electrically connecting the electrode units to which alternating electric signals need to be applied to the alternating power line 57 to apply the alternating electric signals and disconnecting the electrical connection between the electrode units 33 in the area where the alternating electric signals do not need to be applied and the alternating power line 57 to stop applying the alternating electric signals" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the column groups corresponding to the areas (1-5) in the electrode sheet 13 to which the alternating electric signals are to be applied at their signal input terminals 2, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining column groups at the signal acquisition terminal 1.

[0241] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0242] The present application also provides a method for applying an alternating electric signal based on a temperature detection signal, which is used in the above-mentioned tumor treating field treatment system 100. As shown in FIG. 15 , the application method includes:

[0243] Step 710: Start the tumor treating field system 100;

[0244] Step 711: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0245] Step 712: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0246] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 714. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 715.

[0247] Step 714: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712;

[0248] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 716; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 717;

[0249] Step 716: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 712;

[0250] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719;

[0251] Step 718: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0252] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperatures exceed the preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0253] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 721. If the number of over-temperature areas does not exceed the preset number threshold, execute step 724.

[0254] Step 721: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 722;

[0255] Step 722: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 723;

[0256] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 711. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 722.

[0257] Step 724: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 725; if the area is a non-over-temperature area, execute step 726.

[0258] Step 725: Stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 731;

[0259] Step 726: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 727. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 728.

[0260] Step 727: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 731;

[0261] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0262] Step 729: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and execute step 731;

[0263] Step 730: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 731;

[0264] Step 731: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 732 or step 734. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0265] Step 732: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0266] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0267] Step 734: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 735. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 736.

[0268] Step 735: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712;

[0269] Step 736: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 737. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 738.

[0270] Step 737: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 712;

[0271] Step 738: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0, execute step 739. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the preset temperature threshold t0, return to step 719.

[0272] Step 739 : Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712 .

[0273] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0274] Disconnect all control switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0275] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0276] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0277] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 712, 722, and 731 is specifically as follows:

[0278] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end thereof for applying an alternating electrical signal to each electrode unit 33 to the end thereof for collecting temperature of each electrode unit 33, and sequentially close the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0279] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal acquisition terminals 1 thereof, and sequentially closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperatures of the electrode units 33 of the electrode sheet 13; or

[0280] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and sequentially closing the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0281] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electrical signal to transmitting a direct current signal or a temperature detection signal, and the control switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence at a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0282] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 715, 728, and 736 is 40.4°C to 40.6°C, preferably 40.5°C. The preset temperature threshold in steps 717 and 738 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 720 is preferably 2.

[0283] The process of continuing to apply the alternating electrical signal in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0284] disconnecting the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to connect the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0285] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0286] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input ends 2 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0287] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input terminals 2 are closed and the signal acquisition terminals 1 are disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0288] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0289] Increasing the voltage or current amplitude of the currently applied alternating electric signal in step 714, step 727, and step 735 specifically involves boosting the voltage of the currently applied alternating electric signal in a manner of a DC voltage amplitude increment of 0.03 V per second.

[0290] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in steps 718, 730, and 739 specifically involves continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal by 5V and lasting for 3 minutes.

[0291] The process of stopping applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in step 721 is specifically as follows:

[0292] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0293] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected; or

[0294] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to their signal collection terminals 1; or

[0295] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0296] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0297] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 725 is specifically as follows:

[0298] Control the bidirectional switch 55 electrically connected to the electrode units 33 in the over-temperature area to disconnect the electrical connection between the electrode units 33 in the over-temperature area and the alternating power line 57; or

[0299] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from the end where the electrode units 33 in the over-temperature zone are applied with alternating electrical signals to the end where the electrode units 33 in the over-temperature zone are subjected to temperature acquisition; or

[0300] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all signal input terminals 2 for applying alternating electrical signals to each electrode unit 33 in the over-temperature area to their signal collection terminals 1; or

[0301] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the AC power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0302] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0303] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrodes 13 for alternately applying alternating electric fields with different directions. Each electrode 13 can alternately switch between applying alternating electric signals and transmitting temperature detection signals.

[0304] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor therapy field system 100 of the present embodiment further includes a third preset temperature t3. The third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The present embodiment also provides an alternating electric signal control method based on a temperature detection signal for use in the aforementioned tumor therapy field system. Referring to FIG. 16 , the alternating electric signal control method includes:

[0305] Step 810: Start the tumor treating field system 100;

[0306] Step 811: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0307] Step 812: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0308] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 814. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 815.

[0309] Step 814: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0310] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 816; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 817;

[0311] Step 816: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 812;

[0312] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. If there is no electrode unit 33 whose temperature exceeds the third preset temperature t3, execute step 818; if there is an electrode unit whose temperature exceeds the third preset temperature t3, execute step 819.

[0313] Step 818: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0314] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821;

[0315] Step 820: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0316] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperatures exceed a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0317] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 823. If the number of over-temperature areas does not exceed the preset number threshold, execute step 826.

[0318] Step 823: Stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 824;

[0319] Step 824: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 825;

[0320] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 811. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 824.

[0321] Step 826: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 827; if the area is a non-over-temperature area, execute step 828.

[0322] Step 827: Stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 835;

[0323] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0324] Step 829: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0325] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0326] Step 831: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and execute step 835;

[0327] Step 832: Determine whether any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3. If the temperature of any of the electrode units 33 in the non-overtemperature region does not exceed the third preset temperature t3, execute step 833. If any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3, execute step 834.

[0328] Step 833: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0329] Step 834: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0330] Step 835: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 836 or step 838. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0331] Step 836: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0332] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0333] Step 838: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 839. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 840.

[0334] Step 839: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0335] Step 840: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 841. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 842.

[0336] Step 841: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 812;

[0337] Step 842: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3, execute step 843. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the third preset temperature t3, execute step 844.

[0338] Step 843: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0339] Step 844: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0, execute step 845. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the preset temperature threshold t0, return to step 821.

[0340] Step 845 : Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812 .

[0341] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 811 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0342] Disconnect all control switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0343] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0344] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0345] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 812, 824, and 835 is specifically as follows:

[0346] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end thereof for applying an alternating electrical signal to each electrode unit 33 to the end thereof for collecting temperature of each electrode unit 33, and sequentially close the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0347] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal acquisition terminals 1 thereof, and sequentially closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperatures of the electrode units 33 of the electrode sheet 13; or

[0348] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and sequentially closing the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0349] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electrical signal to transmitting a direct current signal or a temperature detection signal, and the control switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence at a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0350] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 815, 830, and 840 is 40.4°C to 40.6°C, preferably 40.5°C. The third preset temperature in steps 817, 832, and 842 is 40.7°C to 40.9°C, preferably 40.8°C. The preset temperature threshold in steps 819 and 844 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 822 is preferably 2.

[0351] The process of continuing to apply the alternating electrical signal in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows:

[0352] disconnecting the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to connect the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0353] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0354] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input ends 2 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0355] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input terminals 2 are closed and the signal acquisition terminals 1 are disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0356] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0357] The method of increasing the voltage or current amplitude of the currently applied alternating electric signal in step 814, step 829, and step 839 is to continue applying the alternating electric signal by boosting the currently applied alternating electric signal with a DC voltage amplitude increment of 0.03V per second and then continuing to apply the alternating electric signal.

[0358] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and for 3 minutes.

[0359] The process of stopping applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in step 823 is specifically as follows:

[0360] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0361] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected; or

[0362] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to their signal collection terminals 1; or

[0363] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0364] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0365] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 827 is specifically as follows:

[0366] Control the bidirectional switch 55 electrically connected to the electrode units 33 in the over-temperature area to disconnect the electrical connection between the electrode units 33 in the over-temperature area and the alternating power line 57; or

[0367] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from the end where the electrode units 33 in the over-temperature zone are applied with alternating electrical signals to the end where the electrode units 33 in the over-temperature zone are subjected to temperature acquisition; or

[0368] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all signal input terminals 2 for applying alternating electrical signals to each electrode unit 33 in the over-temperature area to their signal collection terminals 1; or

[0369] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the AC power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0370] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0371] When the tumor electric field therapy system 100 is in a standby state before starting work, no alternating electric signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switch 55 (55-1 to 55-5) to switch to the signal acquisition terminal 1, and the control switches 54 (54-1 to 54-4) are turned on in sequence. The ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to each row of electrode units 33 (33-1 to 33-20) in sequence.

[0372] When the control switch 54-1 is turned on, the control switches (54-2, 54-3, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-1 to 33-5);

[0373] When the control switch 54-2 is turned on, the control switches (54-1, 54-3, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-6 to 33-10);

[0374] When the control switch 54-3 is turned on, the control switches (54-1, 54-2, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-11 to 33-15);

[0375] When the control switch 54-4 is turned on, the control switches (54-1, 54-2, 54-3) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-16 to 33-20).

[0376] The first controller 51 receives the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits it to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the alternating electric signal applied to each electrode unit 33 through the second controller 37.

[0377] While various operations are depicted in the drawings as following a particular order, this should not be understood as requiring that these operations be performed in the particular order shown or in sequential order, nor should it be understood that all illustrated operations must be performed to achieve desirable results.

[0378] Example 2:

[0379] The key concept of the aforementioned tumor therapy field system 100 is that both the adapter 20 and the electric field generator 30 are equipped with an alternating current power line 57, which controls the synchronous changes in the alternating current signals of all electrode units 33 on an electrode sheet 13, such as the simultaneous increase or decrease of voltage or current. However, different alternating current signals, such as voltages or currents of varying magnitudes, cannot be simultaneously applied to different groups of electrode units 33. Referring to Figures 17 through 20, another tumor therapy field system 100' is described below. Its key concept is the same as that of the aforementioned tumor therapy field system 100, with the difference that each group of electrode units 33' on the corresponding electrode sheet 13' in the adapter 20' and the electric field generator 30' of this tumor therapy field system 100' is equipped with a corresponding alternating current power line 57', enabling the simultaneous application of different alternating current signals, such as voltages or currents of varying magnitudes, to different groups of electrode units 33'.

[0380] Figure 18 is a schematic diagram of the circuit connection between an electrode sheet 13', an adapter 20', and an electric field generator 30' of another tumor electric field therapy system 100' according to an embodiment of the present application. The tumor electric field therapy system 100' includes: at least one pair of electrode sheets 13', an adapter 20' connected to the electrode sheets 13', and an electric field generator 30' connected to the adapter 20'.

[0381] The specific structure of the electrode sheet 13 ′ is the same as that of the electrode sheet 13 , and will not be described in detail here.

[0382] The specific structure of the adapter 20' is similar to that of the above-mentioned adapter 20, with the following differences: referring to Figures 18 and 19, the adapter 20' is provided with five alternating current power lines 57' corresponding to each electrode sheet 13'. The five alternating current power lines 57' are arranged in a one-to-one correspondence with the five column-group electrode units 33' of one electrode sheet 13'. Each electrode sheet 13' is provided with a corresponding bidirectional switch 55' and a grounding switch 54'. The signal input end 2 of the bidirectional switch 55' is electrically connected to a separate alternating current power line 57', so that the tumor electric field therapy system 100' can apply different alternating current signals, such as different voltages or currents, to different column-group electrode units 33' in each electrode sheet 13' as needed.

[0383] The specific structure of the electric field generator 30' is similar to the above-mentioned electric field generator 30, with the following difference: referring to Figures 18 and 20, a power supply switch 40' is provided for each alternating power line 57' connected between the AC signal generator 39' and the adapter 20' to individually control the on and off of the alternating electric signal of each column group electrode unit 33' of each electrode sheet 13'.

[0384] Specifically, referring to Figures 18 and 19, the adapter 20' includes: a first controller 51', multiple groups of ADC units 52' connected to the first controller 51', multiple groups of voltage resistors 53' and multiple groups of control switches 54' corresponding one-to-one to the multiple groups of ADC units 52', multiple groups of bidirectional switching switches 55' connected one-to-one to the multiple groups of ADC units 52', a first communication unit 56', a multi-channel alternating power line 57' connected one-to-one to each group of bidirectional switching switches 55', and a first power supply module 58' connected to the first communication unit 56', the first controller 51' and the multiple groups of ADC units 52'. The first power supply module 58' provides a DC power supply VCC for each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (unnumbered), which are electrically connected one-to-one with the multiple ground lines 18' and the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheet 13' through the first cables 15' of the corresponding electrode sheet 13'. The multiple circuit lines (unnumbered) include multiple different alternating power lines 57' that transmit alternating electrical signals to the corresponding electrode sheet 13' and are electrically connected to the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheet 13', multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheet 13' and are used to supply power to the temperature detection units 35' of the electrode sheet 13' or transmit the temperature detection signals of the electrode sheet 13', and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18' in the substrate 31' of the corresponding electrode sheet 13'. The number L of circuit lines electrically connected between the adapter 20' and one electrode sheet 13' is equal to the sum of the number of rows and columns of the electrode units 33' of the electrode sheet 13'; the number H of circuits electrically connected between the adapter 20' and X electrode sheets 13' is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13', that is, H=XL=X*(M+N). The number of groups of control switches 54' and the number of groups of bidirectional switching switches 55' are both related to the number of electrode sheets 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and is not less than the number of electrode sheets 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' is the same as the number of electrode sheets 13'.

[0385] For example, each group of control switches 54' is provided with a plurality of control switches 54', and the plurality of control switches 54' are respectively connected to the adapter 20' and are respectively electrically connected to the circuit lines (unnumbered) corresponding one to one with the multi-way grounding lines 18' of the corresponding electrode sheet 13', and are configured to control the conduction or disconnection of the multi-way grounding lines 18'. The circuit lines (unnumbered) of the multi-way grounding lines 18' that are electrically connected one by one to the electrode sheet 13' are grounded at one end close to the control switches 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding lines 18' of the substrate 31' of the corresponding electrode sheet 13', and the two are equal in this embodiment. As shown in Figure 18, in this embodiment, the plurality of control switches 54' are respectively a first control switch 54-1', a second control switch 54-2', a third control switch 54-3' and a fourth control switch 54-4'. The multiple control switches 54' in the same group all control the closing or disconnection of the corresponding grounding wire 18' of the same electrode sheet 13' one by one. The first control switch 54-1' is used to control the closing or disconnection of the first grounding wire 18-1' of the corresponding electrode sheet 13', and can then cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-1' to electrode unit 33-5' in the first row group 33 of the electrode sheet 13'; the second control switch 54-2' is used to control the closing or disconnection of the second grounding wire 18-2' of the electrode sheet 13', and can then cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of the temperature detection units 35' corresponding to the five electrode units 33' from electrode unit 33-6' to electrode unit 33-10' in the second row group 33' of the electrode sheet 13'; The control switch 54-3' is used to control the closing or disconnection of the third grounding wire 18-3' of the electrode sheet 13', and can then cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-11' to electrode unit 33-15' in the third row group 33' of the electrode sheet 13'; the fourth control switch 54-4' is used to control the closing or disconnection of the fourth grounding wire 18-4' of the electrode sheet 13', and can then cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-16' to electrode unit 33-20' in the fourth row group 33' of the electrode sheet 13'. The above-mentioned control switch 54' can be a mechanical switch, such as a relay. The control switch 54' can also be an electronic switch, and each control switch 54' can be opened and closed by an additional first controller 51'.

[0386] In this embodiment, the multiple groups of control switches 54' are all electronic switches. The first controller 51' is in communication connection with the multiple groups of control switches 54', and is used to cyclically control the opening and closing states of the multiple control switches 54' in each group of control switches 54', and then turn on each grounding wire 18' of the multiple grounding wires 18' of the corresponding electrode sheet 13' in turn and cooperate with the switching of the corresponding two-way switching switch 55' to collect the temperature of the patient's body surface detected by all temperature detection units 35' on the electrode sheet 13'. The number of each group of control switches 54' is not less than the number of grounding wires 18' of the substrate 31' of the corresponding electrode sheet 13'. In this embodiment, the number of each group of control switches 54' is the same as the number of grounding wires 18' of the corresponding electrode sheet 13'.

[0387] Each set of bidirectional switches 55' includes multiple bidirectional switches 55'. The multiple bidirectional switches 55' in each set are connected to the adapter 20' and are electrically connected to circuit lines (not numbered) that correspond one-to-one with the multiplexed signal lines 19' of a corresponding electrode sheet 13'. The number of bidirectional switches 55' in each set of bidirectional switches 55' is related to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', and is greater than or equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13'. In this embodiment, the number of bidirectional switches 55' is equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13'. Each bidirectional switch 55' has two ends marked 1 and 2. The signal acquisition ends 1 of the multiple bidirectional switches 55' in the same group are electrically connected one by one to the corresponding detection channels of the multiple detection channels of the corresponding group of ADC units 52' through temperature sampling points (unnumbered). The signal input ends 2 of each bidirectional switch 55' in the same group are electrically connected to the corresponding different alternating power lines 57', and are configured to control the multiplexed signal lines 19' to connect to the corresponding different alternating power lines 57' to transmit alternating electrical signals or to connect to the corresponding detection channels of the corresponding group of ADC units 52' to receive the temperature detection signals output by the temperature detection units 35'.

[0388] As shown in Figure 18, taking the electrical connection between one electrode sheet 13' and an adapter 20' as an example, in this embodiment having 20 electrode units 33', the multiple bidirectional switches 55' are respectively a first bidirectional switch 55-1', a second bidirectional switch 55-2', a third bidirectional switch 55-3', a fourth bidirectional switch 55-4', and a fifth bidirectional switch 55-5'. The multiple bidirectional switches 55' in the same group each control the switching between transmitting an alternating electrical signal and transmitting a temperature detection signal on a corresponding one of the multiplexed signal lines 19' of the same electrode sheet 13'. Specifically, the first bidirectional switch 55-1' is used to control the switching of the first dual-purpose signal line 19-1' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-1' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16' in the first column group of the electrode sheet 13' and the conduction of the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16' in the first column group. The switching between the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-16' and the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4' is coordinated to make the first column of electrode units 33-1', electrode units 33-6', electrode units 33-11', and electrode units 33-16' transmit separate alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. signal; the second bidirectional switch 55-2' is used to control the switching of the second dual-purpose signal line 19-2' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-2' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-2', the electrode unit 33-7', the electrode unit 33-12', and the electrode unit 33-17' in the second column group of the electrode sheet 13' and the conduction of the electrode unit 33-2', the electrode unit 33-7', the electrode unit 33-12', and the electrode unit 33-17' in the second column group. The signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-17' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the second column of electrode units 33-2', electrode unit 33-7', electrode unit 33-12', and electrode unit 33-17' transmit separate alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52';The third bidirectional switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-3' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-3', the electrode unit 33-8', the electrode unit 33-13', and the electrode unit 33-18' in the third column group of the electrode sheet 13' and the conduction of the electrode unit 33-3', the electrode unit 33-8', the electrode unit 33-13', and the electrode unit 33-18' in the third column group. The signal end 35-2' of each temperature detection unit 35' corresponding to 33-18' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the third column of electrode units 33-3', electrode unit 33-8', electrode unit 33-13', and electrode unit 33-18' transmit a separate alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. The fourth bidirectional switch 55-4' is used to control the switching of the fourth dual-purpose signal line 19-4' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-4' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-4', the electrode unit 33-9', the electrode unit 33-14', and the electrode unit 33-19' in the fourth column group of the electrode sheet 13' and the conduction of the electrode unit 33-4', the electrode unit 33-9', the electrode unit 33-14', and the electrode unit 33-19' in the fourth column group. The signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-19' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the fourth column of electrode units 33-4', electrode unit 33-9', electrode unit 33-14', and electrode unit 33-19' transmit separate alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the ADC unit 52';The fifth bidirectional switch 55-5' is used to control the fifth dual-purpose signal line 19-5' of the corresponding electrode sheet 13' to switch between transmitting the alternating electric signal output by the alternating power line 57-5' and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-5', the electrode unit 33-10', the electrode unit 33-15', and the electrode unit 33-20' in the fifth column group of the electrode sheet 13' and the conduction of the electrode unit 33-5', the electrode unit 33-10', the electrode unit 33-15', and the electrode unit 33-20' in the fifth column group. The signal ends 35-2' of each temperature detection unit 35' corresponding to 33-20' conduct the switching between the two and cooperate with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the fifth column of electrode units 33-5', electrode unit 33-10', electrode unit 33-15', and electrode unit 33-20' transmit separate alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. When the signal input terminal 2 of each set of bidirectional switches 55' is on and the signal acquisition terminal 1 is off, alternating electrical signals can be transmitted to each electrode unit 33' of each column group of the corresponding electrode sheet 13' via different alternating power lines 57'. When the signal acquisition terminal 1 of each set of bidirectional switches 55' is on and the signal input terminal 2 is off, it can cooperate with each control switch 54' in the corresponding set of control switches 54' to time-share the temperature detection signals collected by the temperature detection units 35' of each electrode element 33' on the electrode sheet 13'. The bidirectional switches 55' can be mechanical switches, such as relays. Alternatively, they can be electronic switches, and each bidirectional switch 55' can be switched by an additional first controller 51'.

[0389] In this embodiment, the multiple sets of bidirectional switches 55' are all electronic switches. The first controller 51' is in communication with the multiple sets of bidirectional switches 55' and is configured to control the multiple bidirectional switches 55' in each set of bidirectional switches 55' to switch between their respective signal acquisition terminals 1 and signal input terminals 2, and to coordinate the closing or opening of the corresponding control switches 54' to continuously monitor the patient's body surface temperature detected by all temperature detection units 35' on the electrode sheet 13' or to transmit an alternating electrical signal to the patient.

[0390] In this embodiment, each group of ADC units 52' is electrically connected to the signal acquisition terminals 1 of the multiple bidirectional switching switches 55' in the corresponding group of bidirectional switching switches 55' through a multi-channel circuit line (not numbered) within the adapter 20', and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19' of the corresponding electrode sheet 13', and convert the temperature detection signal from an analog signal to a digital signal. Each group of ADC units 52' includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding one of the multiplexed signal lines 19' through the corresponding bidirectional switching switch 55'. As shown in Figure 18, each group of ADC units 52' includes a total of five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1' via the signal acquisition terminal 1 of the first bidirectional switch 55-1', the second detection channel B is connected to the second dual-purpose signal line 19-2' via the signal acquisition terminal 1 of the second bidirectional switch 55-2', the third detection channel C is connected to the third dual-purpose signal line 19-3' via the signal acquisition terminal 1 of the third bidirectional switch 55-3', the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' via the signal acquisition terminal 1 of the fourth bidirectional switch 55-4', and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5' via the signal acquisition terminal 1 of the fifth bidirectional switch 55-5'. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature detection unit 35' corresponding to the electrode unit 33' to which the corresponding dual-purpose signal line 19' is connected. In addition, each detection channel A, B, C, D, E is connected to a first power module 58' for providing detection voltage to the detection channel A, B, C, D, E via a corresponding voltage divider resistor 53' in the adapter 20'. The first power module 58' provides DC power.

[0391] In this embodiment, the first communication unit 56' is configured to obtain digital signals output by multiple groups of ADC units 52' and send the digital signals to the electric field generator 30'. The electric field generator 30' is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33' of the electrode sheet 13' based on the received digital signals. For example, when any of the multiple digital signals received exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electric signal output by the electric field generator 30' can be appropriately reduced or stopped to prevent the electrode units 33' of the electrode sheet 13' from becoming too hot when the alternating electric signal is applied, thereby preventing low-temperature burns on the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined based on the human body safety threshold. The first communication unit 56' is controlled by the first controller 51' and serially transmits the digital signals converted by the multiple groups of ADC units 52'. In this embodiment, the preset threshold temperature may be a value within the range of 36°C-45°C.

[0392] Referring to Figure 18, in this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30' and is configured to supply power to the first controller 51', multiple ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is connected between each electrode sheet 13' and the adapter 20'. The first connector 60' is suitable for connecting the corresponding electrode sheet 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30'. The second connector 70' is suitable for connecting the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' located at the end of the second cable 25' away from the first controller 51' and a second socket 72' located on the electric field generator 30'. The second plug 71' and the second socket 72' are push-type spring connectors, meaning that the second connector 70' uses a connector to connect the adapter 20' to the electric field generator 30'. Each first connector 60' (e.g., X1, Y1, X2, and Y2) is connected to the second connector 70' via a corresponding five-way alternating power line 57'. The first connectors 60' (e.g., X1, Y1, X2, and Y2) are also connected to a corresponding set of control switches 54' and a corresponding set of ADC units 52'. Each first connector 60' is connected to the second connector 70' and a corresponding set of ADC units 52' via a corresponding set of bidirectional switches 55'. The second cable 25' has eight conductors, including four five-core conductors 1 through 4 electrically connected to the corresponding five alternating power lines 57' and used to transmit different alternating electrical signals; a conductor 5 electrically connected to the data receive line RX' of the first communication unit 56'; a conductor 6 electrically connected to the data transmit line TX' of the first communication unit 56'; a conductor 7 electrically connected to the VCC power line of the first power module 58'; and a conductor 8 electrically connected to the GND line of the first power module 58'. A second connector 70' is connected to the first communication unit 56' via the data receive line RX' and the data transmit line TX'. The VCC pin of the second connector 70' is connected to the VVC power line of the first power module 58', and the GND pin of the second connector 70' is connected to the GND line of the first power module 58' and is grounded. The VCC pin of the second connector 70' is also connected to the corresponding set of voltage dividers 53' and the corresponding set of ADC units 52' via the VCC power line of the first power module 58'.

[0393] Referring to Figures 18 and 20 , the electric field generator 30' includes a second power module 32', a second controller 37', an AC signal generator 39', a second communication unit 38', and multiple power switches 40'. The VCC pin of the second connector 70' is also electrically connected to the VCC power line of the second power module 32', and the GND pin of the second connector 70' is grounded via the GND line of the second power module 32'. The second power module 32' is also connected to and powered by the second controller 37' and the AC signal generator 39'. The second communication unit 38' is electrically connected to the wire 5 of the second connector 70' via its data receive line RX' and to the wire 6 of the second connector 70 via its data transmit line TX', thereby enabling information exchange between the electric field generator 30' and the adapter 20'. The second controller 37' is also electrically connected to the second communication unit 38', the AC signal generator 39', and the multiple groups of power switches 40'. The second controller 37' is configured to control the opening and closing of each of the multiple groups of power switches 40' and adjust the relevant parameters of the different alternating electrical signals applied by the AC signal generator 39 based on the relevant digital signals received by the second communication unit 38' from the adapter 20'. The AC signal generator 39 is electrically connected to the conductors 1 to 4 that transmit different alternating electrical signals to the second connector 70' through the multiple groups of power switches 40'. Each group of power switches 40' includes multiple power switches 40', and the multiple groups of power switches 40' are arranged in a one-to-one correspondence with the multiple electrode sheets 13'. Each group of power switches 40' is electrically connected to a corresponding five-core conductor 1, 2, 3, 4 in the second connector 70', which transmits alternating electrical signals, via a five-core AC power line 41-1', 41-2', 41-3', 41-4'. The five-core conductors 1, 2, 3, 4 in the second connector 70' are then electrically connected to the corresponding electrode sheet 13' via the corresponding five-core conductors 1, 2, 3, 4 in the second connector 70', thereby transmitting a different alternating electrical signal to each electrode sheet 13. The AC signal generator 39' is electrically connected to multiple groups of power switches 40' via a five-core AC power line 41'. Specifically, the number of power switch 40' groups in the electric field generator 30' is related to the number of electrode sheets 13'. In this embodiment, the number of power switch 40' groups is equal to the number of electrode sheets 13', both of which are four. The number of power switches 40' in each group is related to the number of columns of the corresponding electrode sheets 13'. In this embodiment, the number of power switches 40' in each group is equal to the number of columns of the corresponding electrode sheets 13', both of which are five. The multiple power switch groups 40' include a first power switch group 40-1', a second power switch group 40-2', a third power switch group 40-3', and a fourth power switch group 40-4', which are electrically connected to the five-core wires 1 to 4 of the second connector 70' in a one-to-one correspondence. One end of the first power switch group 40-1' is electrically connected to the AC signal generator 39' via the five-core AC power line 41' of the electric field generator 30'.The other end is electrically connected to the corresponding five-core wire 1 for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-1' and is electrically connected to the five-way alternating power line 57' at the port X1' of the adapter 20' through the five-core wire 1 of the second connector 70', the five-way alternating power line 57' at the port X1' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port X1 of the adapter 20' is electrically connected to the corresponding electrode sheet 13', so as to control whether the AC signal generator 39' sends power to the five corresponding five-way alternating power lines 57' in the electrode sheet 13' at the port X1 of the adapter 20'. The electrode units 33' in the column group transmit different alternating electric signals; one end of the second group of power switches 40-2' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 2 for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-2' and is electrically connected to the five-way alternating power line 57' at the port Y1' of the adapter 20' through the five-core wire 2 of the second connector 70', the five-way alternating power line 57' at the port Y1' of the adapter 20' is electrically connected to the first connector 60', and the first connector at the port Y1' of the adapter 20' is electrically connected to the first connector 60'. The connector 60' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the five column groups corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to the adapter 20' port Y1'; one end of the third group of power switches 40-3' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 3' for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-3' and is connected to the adapter 20' at the end through the five-core wire 3' of the second connector 70'. The five-way alternating power line 57' at port X2' of the adapter 20' is electrically connected, the five-way alternating power line 57' at port X2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at port X2' of the adapter 20' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the five column groups corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to port X2' of the adapter 20'; one end of the fourth power switch 40-4' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30'.The other end is electrically connected to the corresponding five-core conductor 4' transmitting alternating electrical signals in the second connector 70' via a five-core AC power cable 41-4'. The five-core conductor 4 of the second connector 70' is then electrically connected to the five-way AC power cable 57' at port Y2' of the adapter 20'. The five-way AC power cable 57' at port Y2' of the adapter 20' is then electrically connected to the first connector 60'. The first connector 60' at port Y2' of the adapter 20' is then electrically connected to the corresponding electrode sheet 13'. This controls whether the AC signal generator 39' transmits different alternating electrical signals to the electrode units 33' in the five column groups corresponding to the five-way AC power cables 57' in the electrode sheet 13' electrically connected to port Y1' of the adapter 20'.

[0394] The working principle of the tumor electric field treating system 100 ′ of this embodiment will be described in detail below with reference to FIG. 18 to FIG. 20 .

[0395] It should be noted that the operating principle of temperature collection of the tumor treating field system 100 ′ is the same as that of the tumor treating field system 100 , and will not be described in detail here.

[0396] The operating principle of applying alternating electric signals in the tumor therapy field system 100 ′ is similar to that of the tumor therapy field system 100 , except that different alternating electric signals can be applied to electrode units 33 in different columns at the same time, which is more flexible.

[0397] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33' of a certain electrode sheet 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the signal input end 2 of each of the multiple bidirectional switching switches 55' of a group of bidirectional switching switches 55' electrically connected to the electrode sheet 13' to be turned on and the signal acquisition end 1 to be turned off, and controls a group of power supply switches 40' electrically connected to the electrode sheet 13' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply different alternating electric signals to each column group of electrode units 33' of the electrode sheet 13' through different alternating power lines 57', and the voltage or current of the different applied alternating electric signals is adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to connect to different alternating power lines 57 ′, so that different alternating electrical signals are applied to the electrode units 33 of each column group based on different alternating power lines 57 ′.

[0398] It should be noted that, in other embodiments, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' can also be used to control a group of bidirectional switches 55' electrically connected to a certain electrode sheet 13' to apply different alternating electric signals to some electrode units 33' of the electrode sheet 13' in the same time period. For example, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the signal input end 2 of the first bidirectional switch 55-1' among the multiple bidirectional switches 55' of a group of bidirectional switches 55' electrically connected to the electrode sheet 13' to be turned on and the signal acquisition end 1 to be turned off, and controls a group of power switches 40' electrically connected to the electrode sheet 13' and a power switch 40' corresponding to the first bidirectional switch 55-1' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply an alternating electric signal to the first column group electrode unit 33-1', electrode unit 33-6', electrode unit 33-11', and electrode unit 33-16' of the electrode sheet 13' through the corresponding alternating power line 57', and the voltage or current of the applied alternating electric signal is adjustable. It should be noted that, in other embodiments, different alternating electrical signals may be applied simultaneously to two, three or four column groups of electrode units 33 within the same time period, which will not be described in detail here.

[0399] It should be noted that in the embodiment of the present application, the control switch 54' electrically connected to each of the multiple grounding lines 18' of the electrode sheet 13' and the bidirectional switch 55' electrically connected to each of the multiple dual-purpose signal lines 19' of the electrode sheet 13' are both located in the adapter 20'. However, in other embodiments, the control switch 54' electrically connected to the grounding line 18' and the bidirectional switch 55' electrically connected to the dual-purpose signal line 19' can also be located on the electrode sheet 13' or in the electric field generator 30', which will not be described in detail here. In addition, the ADC unit 52' located in the adapter 20' can also be located in the electric field generator 30' and directly controlled by the second controller 37'.

[0400] The tumor electric field therapy system 100' of the present application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 33' on the electrode sheet 13' without increasing the weight of the electrode sheet 13' or adding the core of the first cable 15' electrically connected to the electrode sheet 13', and then determine whether the electrode sheet 13' is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35' of the electrode sheet 13' is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13' needs to be replaced based on the number of faulty or abnormal temperature detection units 35' obtained; or identify the type of the electrode sheet based on the obtained temperature detection signal if the electrode sheet 13' is qualified; or determine whether the electrode unit 33' of the electrode sheet 13' is overheated based on the obtained temperature detection signal if the electrode sheet 13' is qualified, and then control the alternating electric signal applied to the electrode sheet 13' or the electrode units 33' of the corresponding column of the electrode sheet 13', so as to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 13'. In addition, the substrate 31' of the electrode sheet 13' of the present application is electrically connected to the same electrode unit 33' and the signal end 35-2' of the corresponding temperature detection unit 35' through the same dual-purpose signal line 19'. While it can transmit both alternating electrical signals and direct current signals for temperature signal acquisition and the collected temperature detection signals through the dual-purpose signal line 19', it also greatly reduces the number of conductive traces (grounding line 18', dual-purpose signal line 19') laid thereon, reducing the wiring difficulty of the substrate 31', simplifying the manufacturing process, reducing the weight of the substrate 31', and reducing manufacturing costs. The electrode sheet 13' of the present application can also switch between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the collected temperature detection signals through the combined control of a control switch 54' electrically connected to the grounding line 18' laid thereon and a bidirectional switching switch 55' electrically connected to the dual-purpose signal line 19'.

[0401] Specifically, when it is necessary to apply an alternating electric signal to the patient through the electrode units 33' of a certain electrode sheet 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls all the control switches 54' in a group of control switches 54' corresponding to the electrode sheet 13' to be disconnected, and at the same time controls all the bidirectional switches 55' in a group of bidirectional switching switches 55' corresponding to the electrode sheet 13' to be switched to their respective signal input terminals 2, so that the signal acquisition terminals 1 of the bidirectional switching switches 55' are all disconnected and the signal input terminals 2 are all turned on, so that the dual-purpose signal lines 19' of the electrode sheet 13' are electrically connected to the adapter 20' and the multi-channel alternating power lines 57' corresponding to the electrode sheet 13', thereby transmitting the same or different alternating electric signals to the electrode units 33' of the electrode sheet 13'. When the temperature detection signals of the temperature detection units 35' corresponding to all the electrode units 33' of the detected electrode sheet 13' are much lower than the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' controls the AC signal generator 39 through its second controller 37' to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13' through the corresponding multi-channel alternating power lines 57' of the adapter 20', so that the pair of electrode sheets 13' continue to apply the alternating electric signal; when the temperature detection signals of the temperature detection units 35' corresponding to all the electrode units 33' of the detected electrode sheet 13' are lower than but close to the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39' through the second controller 37', thereby reducing the voltage or current of the alternating electric signal. low voltage or current of the alternating electric signal applied to the pair of electrode sheets 13'; when it is detected that the temperature detection signal of the temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode sheet 13' is greater than a preset temperature threshold, the electric field generator 30' controls a group of power switches 40' electrically connected to the electrode sheet 13' to be disconnected through the second controller 37', so as to stop applying the alternating electric signal to the electrode sheet 13'; or the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls all the bidirectional switches 55' of a group of bidirectional switches 55' electrically connected to the electrode sheet 13' to switch from their signal input end 2 to the signal acquisition end 1, that is, controls all the signal acquisition ends 1 of the bidirectional switches of the group of bidirectional switches 55' electrically connected to the electrode sheet 13' to be turned on and all the signal input ends 2 to be turned off, thereby achieving the stop of applying the alternating electric signal to the electrode sheet 13';Or, when it is detected that the temperature detection signal of the temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode sheet 13' is greater than the preset temperature threshold, the second controller 37' of the electric field generator 30' controls a group of power switches 40' electrically connected to the electrode sheet 13' to continue to be turned on, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls a bidirectional switch 55' electrically connected to the electrode unit 33' of the electrode sheet 13' to switch from its signal input end 2 to its signal acquisition end 1, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' simultaneously controls the electrode unit 33' whose temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold. The remaining bidirectional switches 55' electrically connected to the electrode units 33' all continue to maintain electrical connection with their respective signal input terminals 2, thereby ceasing the application of alternating electrical signals to all electrode units 33' in the column containing the electrode units 33' whose temperature detection signals on the electrode sheet 13' exceed the preset temperature threshold. The alternating electrical signals continue to be applied to the remaining columns of electrode units 33' whose temperature detection signals on the electrode sheet 13' do not exceed the preset temperature threshold. The alternating electrical signals applied to the remaining columns of electrode units 33' can be the same or different. For example, the alternating electrical signals may continue to be applied with a reduced voltage or current amplitude for columns whose temperature detection signals do not exceed the preset temperature threshold but are closer to the preset temperature threshold, and may continue to be applied with a increased voltage or current amplitude for columns whose temperature detection signals do not exceed the preset temperature threshold but are further away from the preset temperature threshold. This implements the method for controlling the application of alternating electrical signals based on temperature detection signals in the tumor electric field therapy system 100'.

[0402] It should be noted that the alternating electric signal application method, electrode sheet temperature detection method, electrode sheet temperature anomaly detection method, control method, and electrode sheet type identification method of the tumor electric field therapy system 100' of this embodiment are similar to the control method of the aforementioned tumor electric field therapy system 100. The difference is that the tumor electric field therapy system 100' of this embodiment can also simultaneously apply different alternating electric signals, such as different voltages or currents, to the electrode units 33' in each area (i.e., each column group) according to the temperature of the electrode units 33' in each area to prevent the electrode units 33' in the corresponding area from exceeding the preset temperature threshold, so as to continuously apply the electric field for a long time and improve the treatment effect.

[0403] Specifically, the tumor electric field therapy system 100' of this embodiment can use the electrode sheet temperature detection method shown in Figure 8 to determine the temperature of each electrode unit 33' in the electrode sheet 13'. Please refer to Figure 8 for details and will not be repeated here.

[0404] The tumor electric field therapy system 100' of this embodiment can use the electrode sheet temperature anomaly detection method shown in FIG9 to determine whether the electrode sheet 13' is abnormal. Please refer to FIG9 for details and will not be described in detail here.

[0405] The tumor therapeutic field system 100' of this embodiment can use the control method of the tumor therapeutic field system shown in FIG21 to control the intensity of the alternating electric signal applied to the electrode unit 33', which specifically includes the following steps:

[0406] Step 210 ′: controlling the switching unit so that the dual-purpose signal line 19 ′ corresponding to at least one column group in the corresponding electrode sheet 13 ′ is connected to the corresponding temperature sampling point.

[0407] Step 220 ′: controlling the control switches 54 ′ corresponding to each row group to sample the analog temperature signals of the corresponding electrode units 33 ′ based on the corresponding temperature sampling points to determine the temperature detection signals of the respective electrode units 33 ′ in each electrode sheet 13 ′.

[0408] Step 240 ′: controlling the intensity of the alternating electric signal applied to the electrode unit 33 ′ according to the temperature detection signal.

[0409] Specifically, when the electrode sheet 13' is determined not to need to be replaced, the alternating electric signal applied to each electrode unit 33' in the electrode sheet 13' is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35' corresponding to each electrode unit 33' in the electrode sheet 13'.

[0410] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33' according to the temperature detection signal in step 240' specifically includes the following steps:

[0411] Step 241 ′: comparing the temperature of each electrode unit 33 ′ in the electrode sheet 13 ′ with a preset temperature threshold according to the temperature detection signal.

[0412] Step 242 ′: Control the intensity of the alternating electric signal according to the comparison result.

[0413] In some embodiments, controlling the intensity of the alternating electrical signal according to the comparison result in step 242′ specifically includes:

[0414] Step 2421': When the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33' of the electrode sheet 13'. Specifically, when the temperature detection signals obtained from all electrode units 33' of the electrode sheet 13' show that the temperature detection signal exceeds the preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33' of the electrode sheet 13'. When the temperature detection signals obtained from each electrode unit 33' of the electrode sheet 13' do not exceed the preset temperature threshold, continue applying the alternating electrical signal to each electrode unit 33' of the electrode sheet 13'.

[0415] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33' of the electrode sheet 13' in step 2421' specifically includes: stopping applying the alternating electric signal to all electrode units 33' of the electrode sheet 13'; or stopping applying the alternating electric signal to all electrode units 33' in the column group where the electrode unit 33' in the electrode sheet 13' exceeds the preset temperature threshold.

[0416] Furthermore, when the application of the alternating electric signal to all the electrode units 33' in the column group where the electrode unit 33' exceeding the preset temperature threshold in the electrode sheet 13' is located is stopped, the application of the alternating electric signal to the electrode units 33' in other column groups in the electrode sheet 13' continues. The intensity of the alternating electric signal applied to the electrode units 33' in other column groups in the electrode sheet 13' is adjustable. For example, all the electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in different columns from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the alternating electric signals applied to different column groups may be the same or different. For example, the amplitude of the voltage or current of the alternating electric signal applied to the column group that is closer to the preset temperature threshold but does not exceed the preset temperature threshold is smaller, and vice versa.

[0417] In some other embodiments, controlling the intensity of the alternating electric signal according to the comparison result in step 242′ specifically includes:

[0418] Step 2422': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33' of the electrode sheet 13', wherein the first preset temperature is less than the preset temperature threshold.

[0419] In step 2422', the magnitude of increase in the electric field strength corresponding to each column group whose alternating electric signal strength is increased may be the same or different, that is, they may be adjusted separately. For example, the amplitude of the voltage or current of the alternating electric signal applied to the column group with the lower maximum temperature may be greater, and vice versa.

[0420] Step 2423': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if there is at least one electrode unit 33' in the electrode sheet 13' where the temperature exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength of the electrode unit 33' currently applied to the electrode sheet 13' is maintained unchanged.

[0421] In step 2423', maintaining the strength of the alternating electrical signal currently applied to the electrode unit 33' specifically includes maintaining the strength of the alternating electrical signal currently applied to the first target column group, where the first target column group is a column group having a temperature at the electrode unit 33' exceeding a first preset temperature and less than a preset temperature threshold. In other words, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group having a temperature exceeding the first preset temperature and less than the preset temperature threshold may be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the remaining column groups may still be adjusted based on the temperature of the corresponding column group.

[0422] Step 2424': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33' in the electrode sheet 13' exceeds the second preset temperature and is less than the preset temperature threshold, reduce the intensity of the alternating electric signal applied to the electrode unit 33' of the electrode sheet 13'.

[0423] In step 2424', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target column group, where the second target column group is a column group having an electrode unit 33' with a temperature exceeding a second preset temperature and less than a preset temperature threshold. In other words, the amplitude of the voltage or current of the alternating electrical signal corresponding to the column group having a temperature exceeding the second preset temperature and less than the preset temperature threshold may be reduced, and the reduced amplitudes may be the same or different. The amplitudes of the voltage or current of the alternating electrical signal corresponding to the remaining column groups may still be adjusted based on the temperature of the corresponding column group, for example, maintained or increased.

[0424] Exemplarily, when the temperature detection signal is far below a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitudes of the alternating electric signal applied to different column groups may be the same or different, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged. When the temperature detection signal approaches a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that keeps the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that reduces the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitude of the alternating electric signal applied to different column groups may be the same or different.

[0425] In some other embodiments, controlling the intensity of the alternating electrical signal according to the comparison result in step 242′ specifically includes:

[0426] Step 2425 ′: When the temperature of at least one electrode unit 33 ′ exceeds a preset temperature threshold, determine the number of over-temperature column groups.

[0427] Step 2426 ′: when the number of over-temperature column groups exceeds a preset threshold, stop applying the alternating electrical signal to all electrode units 33 ′ of the electrode sheet 13 ′.

[0428] Step 2427 ′: when the number of over-temperature column groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 ′ in the column group where the electrode units 33 ′ exceeding the preset temperature threshold are located in the electrode sheet 13 ′.

[0429] Furthermore, when the application of the alternating electric signal to all the electrode units 33' in the column group where the electrode unit 33' exceeding the preset temperature threshold in the electrode sheet 13' is located is stopped, the application of the alternating electric signal to the electrode units 33' in other column groups in the electrode sheet 13' continues. The intensity of the alternating electric signal applied to the electrode units 33' in other column groups in the electrode sheet 13' is adjustable. For example, all the electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in different columns from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the alternating electric signals applied to different column groups may be the same or different. For example, the amplitude of the voltage or current of the alternating electric signal applied to the column group that is closer to the preset temperature threshold but does not exceed the preset temperature threshold is smaller, and vice versa.

[0430] Step 2428': When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature at each electrode unit 33' in the non-over-temperature column group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33' of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0431] In step 2428', the magnitude of increase in the electric field strength corresponding to each column group whose alternating electric signal strength is increased may be the same or different, that is, they may be adjusted separately. For example, the amplitude of the voltage or current of the alternating electric signal applied to the column group with the lower maximum temperature may be greater, and vice versa.

[0432] Step 2429': When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33' in the non-over-temperature column group exceeds the first preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit 33' of the non-over-temperature column group remains unchanged.

[0433] In step 2429', maintaining the strength of the alternating electrical signal currently applied to the electrode unit 33' specifically includes maintaining the strength of the alternating electrical signal currently applied to the first target column group, where the first target column group is a column group having a temperature at the electrode unit 33' exceeding a first preset temperature and less than a preset temperature threshold. In other words, only the voltage or current amplitude of the alternating electrical signal corresponding to the column group having a temperature exceeding the first preset temperature and less than the preset temperature threshold may be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the remaining column groups may still be adjusted based on the temperature of the corresponding column group.

[0434] Step 2430': When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33' in the non-over-temperature column group exceeds the second preset temperature and is less than the preset temperature threshold, then reduce the intensity of the alternating electric signal applied to the electrode unit 33' of the non-over-temperature column group, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0435] In step 2430', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target column group, where the second target column group is a column group having an electrode unit 33' with a temperature exceeding a second preset temperature and less than a preset temperature threshold. In other words, the amplitude of the voltage or current of the alternating electrical signal corresponding to the column group having a temperature exceeding the second preset temperature and less than the preset temperature threshold may be reduced, and the reduced amplitudes may be the same or different. The amplitudes of the voltage or current of the alternating electrical signal corresponding to the remaining column groups may still be adjusted based on the temperature of the corresponding column group, for example, maintained or increased.

[0436] Exemplarily, when the temperature detection signal is far below a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitudes of the alternating electric signal applied to different column groups may be the same or different, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged. When the temperature detection signal approaches a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that keeps the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that reduces the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitude of the alternating electric signal applied to different column groups may be the same or different.

[0437] The tumor electric field therapy system 100 ′ of this embodiment can use the electrode sheet type identification method shown in FIG11 to identify the type of the electrode sheet 13 ′. Please refer to FIG11 for details, which will not be described in detail here.

[0438] The tumor electric field therapy system 100' of this embodiment can adopt the signal control method for tumor electric field therapy shown in Figure 22, and combine the control switch 54' and the bidirectional switching switch 55' electrically connected to the electrode sheet 13' to control each electrode unit 33' of the electrode sheet 13' to switch between applying an alternating electric signal and collecting a temperature detection signal.

[0439] Referring to FIG. 22 , the method includes:

[0440] Step 310 ′: Combining and controlling the control switch 54 ′ and the bidirectional switch 55 ′ electrically connected to the corresponding electrode sheet 13 ′ to apply an alternating electrical signal to each electrode unit 33 ′ of the electrode sheet 13 ′ and executing step 320 ′;

[0441] Applying the alternating electrical signal to each electrode unit 33 ′ of the electrode sheet 13 ′ in step 310 ′ specifically includes: simultaneously applying the same or different alternating electrical signals to the electrode units 33 ′ of some or all column groups in all column groups.

[0442] Step 320 ′: Combining and controlling the control switch 54 ′ and the bidirectional switch 55 ′ electrically connected to the electrode sheet 13 ′ to collect temperature detection signals of the electrode units 33 ′ of the electrode sheet 13 ′ in rows and executing step 330 ′;

[0443] The row-wise collection of the temperature detection signals of the electrode units 33' of the electrode sheet 13' in step 320' specifically includes: sampling the temperature detection signals of some row groups or all electrode units 33' of all row groups in sequence in the same sampling time period; or sampling the temperature detection signals of some row groups or some electrode units 33' of all row groups in sequence in the same sampling time period.

[0444] Step 330': determining the combined control mode of the control switch 54' and the bidirectional switch 55' electrically connected to the electrode sheet 13' according to the collected temperature detection signal and executing step 340';

[0445] Step 340 ′: controlling the working state of each electrode unit 33 ′ of the electrode sheet 13 ′ according to the determined combined control mode of the control switch 54 ′ and the bidirectional switch 55 ′.

[0446] The working state of each electrode unit 33' of the electrode sheet 13' in step 340' includes at least one of: stopping applying the alternating electric signal and continuing to collect the temperature detection signal; and stopping collecting the temperature detection signal and continuing to apply the alternating electric signal. Continuing to apply the alternating electric signal includes: continuing to apply the alternating electric signal in a manner that increases the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner that maintains the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner that reduces the voltage or current amplitude of the currently applied alternating electric signal. The manner of continuing to apply the alternating electric signal corresponding to different column groups may be the same or different.

[0447] The operating state of each electrode unit 33' of the electrode sheet 13' is determined by the temperature detection signal it collects. Each electrode unit 33' of the electrode sheet 13' is divided into different regions. A control switch 54' and a bidirectional switch 55' are combined to control each electrode unit 33' in each region to cyclically switch between applying an alternating electrical signal and collecting a temperature detection signal. When applying the alternating electrical signal, different regions can have the same or different temperature detection signals.

[0448] The tumor electric field therapy system 100 ′ of this embodiment can use the electrode sheet temperature detection method shown in FIG13 to detect the temperature of the electrode sheet 13 ′. Please refer to FIG13 for details, which will not be described in detail here.

[0449] The tumor electric field therapy system 100' of this embodiment can apply an alternating electric signal to the electrode sheet 13' using the method for applying an alternating electric signal for tumor electric field therapy shown in Figures 14 to 16. The difference is that when applying the alternating electric signal, the alternating electric signals applied by different column groups can be the same or different, and the details will not be elaborated here.

[0450] The present application also provides a tumor electric field therapy system 100 or 100', comprising: at least one pair of the aforementioned electrode sheets 13 or 13'; an electric field generator 30 or 30', the electric field generator 30 or 30' being used to generate an alternating power supply and transmit the alternating power supply to each electrode sheet 13 or 13' via an alternating power line 57 or 57'; a control unit (such as a first controller 51 or 51' or a second controller 37 or 37', etc.), the control unit being used to configure at least one of the switching state of the control switch 54 or 54' and the switching state of the switching unit (unnumbered) so as to sample the analog temperature signal detected by the corresponding temperature detection unit 35 or 35' in each row group based on the corresponding temperature sampling point (unnumbered), or to control the electrode units 33 or 33' of at least one column group to be applied with an alternating electric signal based on the alternating power line 57 or 57'.

[0451] The present application also provides a tumor treatment device (not shown), comprising: the aforementioned tumor electric field treatment system 100 or 100 ′.

[0452] The present application also provides a computer-readable storage medium having a computer program stored thereon. When the computer program is executed by a processor, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0453] The present application also provides an adapter 20 or 20' for tumor electric field therapy, including a first memory (not shown) and a first controller 51 or 51'. The first memory (not shown) stores a computer program. When the computer program is executed by the first controller 51 or 51', it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0454] The present application also provides an electric field generator 30 or 30' for tumor electric field therapy, including a second memory (not shown) and a second controller 37 or 37'. The second memory (not shown) stores a computer program. When the computer program is executed by the second controller 37 or 37', it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0455] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. A tumor electrotherapy system, characterized in that, Comprising: At least a pair of electrode plates, each of the electrode plates includes a plurality of electrode units and a plurality of temperature detection units, each of the electrode units can apply an alternating electric signal, and each of the temperature detection units is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein, The plurality of electrode units are configured as at least two row groups and at least two column groups. The grounding ends of the temperature detection units in each row group are commonly connected to a ground pin through a control switch. After the signal ends of the temperature detection units in each column group are respectively short-circuited with the corresponding electrode units, they are commonly connected to a switching unit through a dual-purpose signal line; The switching unit is configured to switch the dual-purpose signal line to be connected to a temperature sampling point or an alternating power supply line, so that When the dual-purpose signal line is connected to the temperature sampling point, by configuring the switch state of the control switch, the analog temperature signals detected by the corresponding temperature detection units in each row group are sampled based on the temperature sampling point; When the dual-purpose signal line is connected to the alternating power supply line, the electrode units of at least one column group are applied with the alternating electric signal based on the alternating power supply line.

2. The tumor electric field therapy system according to claim 1, wherein The switching unit is further configured to switch the dual-purpose signal lines corresponding to each column group to be respectively connected to the corresponding temperature sampling points, so that according to the configured switch state of the control switch, the analog temperature signals detected by each temperature detection unit in each column group are respectively sampled.

3. The tumor electro-field therapy system according to claim 1, wherein The switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two column groups to be simultaneously connected to the corresponding temperature sampling points, so that according to the configured switch state of the control switch, the analog temperature signals detected by the corresponding temperature detection units in each row group are respectively sampled based on the corresponding temperature sampling points.

4. The tumor electric field therapy system according to any one of claims 1-3, characterized in that, The switching unit includes at least two bidirectional switching switches. The first end of each bidirectional switching switch is connected to the dual-purpose signal line corresponding to each column group. The second end of each bidirectional switching switch is simultaneously connected to the alternating power supply line. The third end of each bidirectional switching switch is connected to the temperature sampling point of the corresponding column group.

5. The tumor electric field therapy system according to claim 4, characterized in that, The switching unit is further configured to switch the dual-purpose signal lines corresponding to each column group to be respectively connected to the alternating power supply line, so that the electrode units of each column group are simultaneously applied with the alternating electric signal based on the alternating power supply line.

6. The tumor electric field therapy system according to claim 4, wherein The switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two column groups to be simultaneously connected to the alternating power supply line, so that the electrode units of at least two column groups are simultaneously applied with the alternating electric signal based on the alternating power supply line.

7. The tumor electro-field therapy system according to claim 4, wherein The intensity of the alternating electric signal output by the alternating power supply line is adjustable.

8. The tumor electric field therapy system according to any one of claims 1-3, characterized in that, The switching unit includes at least two bidirectional switching switches. The first end of each bidirectional switching switch is connected to the dual-purpose signal line corresponding to each column group. The second end of each bidirectional switching switch is connected to different alternating power supply lines. The third end of each bidirectional switching switch is connected to the temperature sampling point of the corresponding column group.

9. The tumor electric field therapy system according to claim 8, wherein, The switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two column groups to be connected to different alternating power lines, so that each electrode unit of each column group is respectively applied with the alternating electric signal based on different alternating power lines.

10. The tumor electric field therapy system according to claim 8, wherein, The intensities of the alternating electric signals output by different alternating power lines are respectively adjustable.

11. The tumor electric field therapy system according to claim 1, characterized in that, Each temperature detection unit includes a temperature sensor and a diode. The temperature sensor has a signal terminal and a ground terminal. The diode has an anode and a cathode. The anode of the diode is connected to the ground terminal of the temperature sensor. The cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

12. The tumor electric field therapy system according to claim 1, wherein Each temperature sampling point is connected to a DC power supply through a corresponding voltage dividing resistor.

13. The tumor electric field therapy system according to claim 12, characterized in that, It further includes an adapter, wherein the control switch, the switching unit, and the voltage dividing resistor are respectively arranged in the adapter.

14. The tumor electric field therapy system according to claim 13, wherein, The adapter includes a first controller and an ADC unit. The ADC unit is connected to each temperature sampling point to sample the analog temperature signal through each temperature sampling point. The first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit according to the digital temperature signal output by the ADC unit.

15. The tumor electro-field therapy system according to claim 14, wherein The first controller is further configured to configure the switch state of the control switch.

16. The tumor electric field therapy system according to claim 14, wherein, The first controller is further configured to configure the switch state of the bidirectional switch in the switching unit.

17. The tumor electric field therapy system according to claim 1, wherein It further includes an electric field generator, which is configured to output the alternating electric signal through the alternating power line.

18. The tumor electro-field therapy system according to claim 17, wherein, The electric field generator includes a second controller and an AC signal generator. The second controller is connected to the AC signal generator. The second controller is configured to control the AC signal generator to adjust the intensity of the alternating electric signal output by the alternating power line.

19. The tumor electric field therapy system according to claim 18, wherein, The electric field generator is further configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

20. The tumor electro-field therapy system according to claim 18, wherein The electric field generator further includes a power supply switch, which is arranged between the AC signal generator and the switching unit. The power supply switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line under the configuration of the second controller.

21. The tumor electro-field therapy system according to claim 18, wherein, The second controller is further configured to configure the switch state of the control switch.

22. The tumor electric field therapy system according to claim 18, wherein The second controller is further configured to configure the switch state of the bidirectional switch in the switching unit.

23. An electrode sheet, characterized in that, Applied to a tumor electric field treatment system, the tumor electric field treatment system includes a switching unit, and the electrode patch includes: A substrate; A plurality of electrode units and a plurality of temperature detection units arranged on the substrate. Each electrode unit can be applied with an alternating electric signal. Each temperature detection unit is arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, wherein, The plurality of electrode units are configured as at least two row groups and at least two column groups; The grounding terminals of the temperature detection units in each of the row groups are commonly connected to a grounding pin through a control switch; After the signal terminals of the temperature detection units in each of the column groups are respectively short-circuited with the corresponding electrode units, they are commonly connected to the switching unit through a dual-purpose signal line, so as to switch the dual-purpose signal line to be connected to the temperature sampling point or the alternating power supply line through the switching unit; When the dual-purpose signal line is connected to the temperature sampling point, by configuring the switch state of the control switch, the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the temperature sampling point; When the dual-purpose signal line is connected to the alternating power supply line, the electrode units of at least one of the column groups are applied with the alternating current signal based on the alternating power supply line.

24. The electrode sheet according to claim 23, wherein When the dual-purpose signal lines corresponding to each of the column groups are respectively connected to the corresponding temperature sampling points, by configuring the switch state of the control switch, the analog temperature signals detected by the respective temperature detection units in each of the column groups are respectively sampled.

25. The electrode sheet according to claim 23, wherein When the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the corresponding temperature sampling points, by configuring the switch state of the control switch, the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are respectively sampled based on the corresponding temperature sampling points.

26. The electrode sheet according to claim 23, characterized in that, When the dual-purpose signal lines corresponding to each of the column groups are respectively connected to the alternating power supply line, the electrode units of each of the column groups are simultaneously applied with the alternating current signal based on the alternating power supply line.

27. The electrode sheet according to claim 23, characterized in that, When the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the alternating power supply line, the electrode units of at least two of the column groups are simultaneously applied with the alternating current signal based on the alternating power supply line.

28. The electrode sheet according to claim 23, wherein, The intensity of the alternating current signal output by the alternating power supply line is adjustable.

29. The electrode sheet according to claim 23, wherein When the dual-purpose signal lines corresponding to the at least two column groups are connected to different alternating power supply lines, the respective electrode units of each of the column groups are respectively applied with the alternating current signal based on different alternating power supply lines.

30. The electrode sheet according to claim 29, wherein, The intensities of the alternating current signals output by different alternating power supply lines are respectively adjustable.

31. The electrode sheet according to claim 23, wherein, Each of the temperature detection units includes a temperature sensor and a diode. The temperature sensor has a signal terminal and a grounding terminal. The diode has an anode and a cathode. The anode of the diode is connected to the grounding terminal of the temperature sensor. The cathode of the diode serves as the grounding terminal of the temperature detection unit. The signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

32. The electrode sheet according to claim 23, characterized in that, Each of the temperature sampling points is connected to a DC power supply through a corresponding voltage-dividing resistor.

33. The electrode sheet according to any one of claims 23-32, characterized in that, Each of the electrode units is provided with a perforation, and the perforation is adapted to receive the temperature detection unit.

34. The electrode sheet according to any one of claims 23-32, characterized in that, The multiple electrode units and the multiple temperature detection units are arranged in an array in terms of spatial layout, and the multiple electrode units and the multiple temperature detection units are arranged in multiple row groups and multiple column groups in terms of circuit connection.

35. The electrode sheet according to claim 34, characterized in that, Both the multiple electrode units and the multiple temperature detection units are 20, and they are arranged in a four-row group and a five-column group in terms of circuit connection.

36. A tumor electrotherapy system, characterized in that, Comprising: At least a pair of electrode sheets according to any one of claims 23-35; An electric field generator for generating an alternating power supply and transmitting the alternating power supply to each of the electrode plates through the alternating power supply line; A control unit for configuring at least one of the switching state of the control switch and the switching state of the switching unit, so as to sample the analog temperature signal detected by the corresponding temperature detection unit in each row group based on the corresponding temperature sampling point, or control the electrode units of at least one column group to be applied with the alternating electric signal based on the alternating power supply line.

37. A tumor treatment device, characterized in that, Comprising: The tumor electric field therapy system according to any one of claims 1-22, or the tumor electric field therapy system according to claim 36.

38. A method for detecting the temperature of an electrode sheet, characterized in that, Applied to the tumor electric field therapy system according to any one of claims 1-22 or applied to the tumor electric field therapy system according to claim 36, the method comprising: Controlling the switching unit to connect at least one of the dual-purpose signal lines corresponding to each column group in the corresponding electrode plate to the corresponding temperature sampling point; Controlling the control switch corresponding to each row group to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

39. The method according to claim 38, wherein When the dual-purpose signal lines corresponding to each column group are respectively connected to the corresponding temperature sampling points, controlling the control switch corresponding to each row group includes: Controlling the control switch corresponding to each row group to be closed in sequence to sample the analog temperature signals of the respective electrode units in each column group respectively.

40. The method according to claim 38, characterized in that, When the dual-purpose signal lines corresponding to at least two column groups are simultaneously connected to the corresponding temperature sampling points, controlling the control switch corresponding to each row group includes: Controlling the control switch corresponding to each row group to be closed in sequence to sample the analog temperature signals of the corresponding electrode units in each row group respectively.

41. A method for detecting electrode sheet abnormalities, characterized in that, A preset threshold is preset in the adapter or the electric field generator, and the method includes: Determining the temperature detection signals of the respective electrode units in each electrode plate by executing the electrode plate temperature detection method according to any one of claims 38-40; Judging whether the electrode plate is abnormal according to the temperature detection signal.

42. The method according to claim 41, wherein Judging whether the electrode plate is abnormal according to the temperature detection signal includes: When it is determined according to the temperature detection signal that any one of the electrode units in the corresponding electrode plate is abnormal or fails, determining that the electrode plate is unqualified.

43. The method according to claim 41, characterized in that, Judging whether the electrode plate is abnormal according to the temperature detection signal includes: When it is determined according to the temperature detection signal that there are abnormal or faulty electrode units in the corresponding electrode plate, determining the number of abnormal or faulty electrode units; When the number of abnormal or faulty electrode units reaches the preset threshold, determining that the electrode plate needs to be replaced.

44. The method according to claim 41, wherein, Judging whether the electrode plate is abnormal according to the temperature detection signal includes: Comparing the temperatures at the respective electrode units in the corresponding electrode plate with a preset temperature threshold according to the temperature detection signal; Judging whether the temperature of the electrode plate is abnormal according to the comparison result.

45. The method according to claim 44, characterized in that, Judging whether the temperature of the electrode sheet is abnormal according to the comparison result, including: When the temperature at any one electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet is abnormal.

46. A control method for a tumor electrotherapy system, characterized in that, A preset temperature threshold, a preset quantity threshold, a first preset temperature, and a second preset temperature are preset in the adapter or the electric field generator, and the method includes: Determining the temperature detection signals of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method described in any one of claims 38-40; Controlling the intensity of the alternating current signal applied to the electrode unit according to the temperature detection signal.

47. The method according to claim 46, wherein Controlling the intensity of the alternating current signal applied to the electrode unit according to the temperature detection signal, including: Comparing the temperature at each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; Controlling the intensity of the alternating current signal according to the comparison result.

48. The method according to claim 47, wherein Controlling the intensity of the alternating current signal according to the comparison result, including: When the temperature at at least one electrode unit exceeds the preset temperature threshold, stopping applying the alternating current signal to the electrode units of the electrode sheet.

49. The method according to claim 48, wherein Stopping applying the alternating current signal to the electrode units of the electrode sheet includes: Stopping applying the alternating current signal to all electrode units of the electrode sheet; or Stopping applying the alternating current signal to all electrode units in the column group where the electrode units exceeding the preset temperature threshold are located in the electrode sheet.

50. The method according to claim 47, wherein Controlling the intensity of the alternating current signal according to the comparison result, including: When the temperature at at least one electrode unit exceeds the preset temperature threshold, determining the number of over-temperature column groups; When the number of over-temperature column groups exceeds the preset quantity threshold, stopping applying the alternating current signal to all electrode units of the electrode sheet; When the number of over-temperature column groups does not exceed the preset quantity threshold, stopping applying the alternating current signal to all electrode units in the column group where the electrode units exceeding the preset temperature threshold are located in the electrode sheet.

51. The method according to claim 49 or 50, characterized in that, When stopping applying the alternating current signal to all electrode units in the column group where the electrode units exceeding the preset temperature threshold are located in the electrode sheet, the method further includes: Continuing to apply the alternating current signal to the electrode units in other column groups of the electrode sheet.

52. The method according to claim 51, wherein The intensity of the alternating current signal applied to the electrode units in other column groups of the electrode sheet is adjustable.

53. The method according to claim 51, wherein The intensity of the alternating current signal applied to the electrode units in each column group among the other column groups is respectively adjustable.

54. The method according to claim 47, wherein, Controlling the intensity of the alternating current signal according to the comparison result, including: When the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, if the temperatures at all electrode units in the electrode sheet do not exceed the first preset temperature, increasing the intensity of the alternating current signal applied to the electrode units of the electrode sheet, where the first preset temperature is less than the preset temperature threshold.

55. The method according to claim 54, wherein When the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method further includes: If the temperature at at least one electrode unit in the electrode sheet exceeds a first preset temperature and is less than a preset temperature threshold, the alternating current signal intensity currently applied to the electrode unit of the electrode sheet is kept unchanged.

56. The method according to claim 55, wherein When the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method further includes: If the temperature at at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than the preset temperature threshold, the alternating current signal intensity applied to the electrode unit of the electrode sheet is decreased, where the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

57. The method according to claim 50, characterized in that, When the number of over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature at each electrode unit in the non-over-temperature column groups does not exceed the first preset temperature, the alternating current signal intensity applied to the electrode units of the non-over-temperature column groups is increased, where the first preset temperature is less than the preset temperature threshold.

58. The method according to claim 57, wherein When the number of over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature at at least one electrode unit in the non-over-temperature column groups exceeds the first preset temperature and is less than the preset temperature threshold, the alternating current signal intensity currently applied to the electrode units of the non-over-temperature column groups is kept unchanged.

59. The method according to claim 58, characterized in that, When the number of over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature at at least one electrode unit in the non-over-temperature column groups exceeds the second preset temperature and is less than the preset temperature threshold, the alternating current signal intensity applied to the electrode units of the non-over-temperature column groups is decreased, where the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

60. The method according to claim 54 or 57, characterized in that, The increase amplitudes of the electric field strengths corresponding to the column groups where the alternating current signal intensity is increased are the same.

61. The method according to claim 54 or 57, characterized in that, The increase amplitudes of the electric field strengths corresponding to the column groups where the alternating current signal intensity is increased are different from each other. The method according to claim 55 or 58, characterized in that Keeping the alternating current signal intensity currently applied to the electrode unit unchanged includes: Keeping the alternating current signal intensity currently applied to the first target column group unchanged, where the first target column group is the column group where the temperature at the electrode unit exceeds the first preset temperature and is less than the preset temperature threshold.

63. The method according to claim 56 or 59, characterized in that, Decreasing the alternating current signal intensity applied to the electrode unit includes: Decreasing the alternating current signal intensity applied to the electrode units of the second target column group, where the second target column group is the column group where the temperature at the electrode unit exceeds the second preset temperature and is less than the preset temperature threshold.

64. A method for identifying the type of electrode sheet, characterized in that, The method includes: Determining the temperature detection signals of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method according to any one of claims 38 - 40; Identifying the type of the electrode sheet according to the temperature detection signals.

65. A computer-readable storage medium, characterized in that, Stored thereon is a computer program which, when executed by a processor, implements The electrode sheet temperature detection method according to any one of claims 38 - 40; or The electrode sheet abnormality detection method according to any one of claims 41 - 45; or The control method of the tumor electric field therapy system according to any one of claims 46-63; or The electrode type identification method according to claim 64.

66. An adapter for tumor electrotherapy, comprising a first memory and a first controller, characterized in that, The first memory stores a computer program, which when executed by the first controller, realizes The electrode temperature detection method according to any one of claims 38-40; or The electrode abnormality detection method according to any one of claims 41-45; or The control method of the tumor electric field therapy system according to any one of claims 46-63; or The electrode type identification method according to claim 64.

67. An electric field generator for tumor electric field therapy, comprising a second memory and a second controller, characterized in that, The second memory stores a computer program, which when executed by the second controller, realizes The electrode temperature detection method according to any one of claims 38-40; or The electrode abnormality detection method according to any one of claims 41-45; or The control method of the tumor electric field therapy system according to any one of claims 46-63; or The electrode type identification method according to claim 64.

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