Efficient filter oxygenator

Abstract

The present invention provides an efficient filter oxygenator, which comprises a housing and an oxygenation variable-temperature module. A blood inlet, a water inlet, and a water outlet are formed in the bottom of the housing, an air outlet and a blood outlet are formed in the lower part of the housing, and an air inlet and an exhaust opening are formed in the upper part of the housing. The oxygenation variable-temperature module is vertically arranged in the housing. The oxygenation variable-temperature module sequentially comprises a drainage assembly, a variable-temperature film, a first filter screen, an oxygen pressure film, and a second filter screen from inside to outside. The variable-temperature film is in communication with the water inlet and the water outlet. The oxygen pressure film is in communication with the air inlet and the air outlet. A blood inlet end of the drainage assembly is in communication with the blood inlet, and a blood outlet end thereof is located at the upper part of the variable-temperature film. The hole diameter of the second filter screen is smaller than that of the first filter screen. Blood reaches the upper part of the variable-temperature film from the blood inlet through the drainage assembly, is diffused to the periphery by taking the drainage assembly as the center, obliquely penetrates through the variable-temperature film, the first filter screen, the oxygen pressure film, and the second filter screen from top to bottom, and then flows out from the blood outlet. The present invention achieves a good filtering effect without increasing excessive pressure drop and blood priming volume.

Description

High efficiency filtered oxygenator Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to a high-efficiency filtering oxygenator. Background Art

[0002] Extracorporeal circulation devices used in clinical surgery, commonly known as artificial lungs or oxygenators, play a vital role in extracorporeal circulation (CPB) and extracorporeal membrane oxygenation (ECMO). Their primary function is to convert oxygen-depleted venous blood into oxygen-rich arterial blood, replacing lung function and meeting the needs of patients during surgery.

[0003] Because emboli, including bubbles and solid particles, may be present in the withdrawn blood, direct reinfusion into the human body can cause vascular embolism. Therefore, during extracorporeal circulation, in addition to using an oxygenator to exchange gases and maintain the patient's oxygen supply, a filter is also used to intercept emboli in the blood. The filter serves as a safety barrier for blood return to the human body. Prior art designs integrate the filter with the oxygenator. For example, in oxygenator structures where blood flows from the inside out, the filter is a filter mesh that wraps around the oxygenator's outermost silk membrane. In oxygenator structures where blood flows from the outside in, the filter is a filter mesh that wraps around the oxygenator's innermost silk membrane.

[0004] However, for oxygenators designed for outside-in blood flow, the internal space is often enlarged to accommodate a sufficiently large filter to meet filtration requirements. However, this design increases the size of the oxygenator and the blood priming volume, making it unsuitable for infants and young children. For oxygenators designed for inside-out blood flow, the filter area is increased, eliminating the need for a significant increase in the oxygenator's size. However, whether the blood flows from the inside to the outside or from the outside to the inside in an oxygenator, due to the different sizes of bubbles and particles mixed in the blood, in order to meet the filtration requirements, the mesh size of the filter is usually designed to be very small, resulting in poor blood permeability. The pressure loss of the blood increases sharply when it flows through the filter. The pressure loss of the oxygenator determines the maximum output capacity of the blood pump and the speed difference under the same flow rate. The greater the pressure loss of the oxygenator itself, the faster the blood pump needs to maintain the flow rate, thereby exacerbating blood damage. At the same time, the increased blood flow rate shortens the contact time between the blood and the oxygen pressure membrane wire, reducing the oxygenation efficiency. In addition, the increased blood flow rate will also disperse large bubbles into small bubbles. The increase in small bubbles further weakens the permeability of the blood at the filter. In view of the above situation, it is necessary to design an oxygenator with a small pre-charge volume, small pressure loss and good filtration effect to meet the functional needs of critical emergency scenarios.

[0005] Summary of the Invention

[0006] In view of the shortcomings of the prior art, the present invention aims to provide a high-efficiency filter oxygenator that can achieve better filtering effect without increasing the pressure drop, increasing the blood priming volume, or directly reducing the blood priming volume.

[0007] The present disclosure provides a high-efficiency filtering oxygenator, comprising:

[0008] The shell has a blood inlet, a water inlet, and a water outlet at the bottom, an air outlet and a blood outlet at the lower part, and an air inlet and an air outlet at the upper part;

[0009] an oxygenation temperature-variable module, vertically disposed in the housing, comprising, from the inside out, a drainage assembly, a temperature-variable membrane, a first filter, an oxygen pressure membrane, and a second filter; the temperature-variable membrane communicating with the water inlet and the water outlet, the oxygen pressure membrane communicating with the air inlet and the air outlet; a blood inlet end of the drainage assembly communicating with the blood inlet, and a bleeding end located above the temperature-variable membrane; and a pore size of the second filter being smaller than that of the first filter.

[0010] Blood flows from the blood inlet through the drainage component to the upper part of the temperature-variable membrane, diffuses in all directions with the drainage component as the center, and obliquely passes through the temperature-variable membrane, the first filter, the oxygen pressure membrane and the second filter from top to bottom, and then flows out from the bleeding port. The gas in the shell can be discharged through the exhaust port.

[0011] Optionally, the pore size of the first filter is 70 μm to 100 μm; the pore size of the second filter is not greater than 40 μm.

[0012] Optionally, the ratio of the outer diameter of the oxygen pressure membrane to the effective contact height of the oxygen pressure membrane is 1:1 to 2:1.

[0013] Optionally, the drainage assembly includes a drainage tube, which is provided with a first drainage port and a second drainage port, the first drainage port being connected to the blood inlet, and the second drainage port being located on the upper part of the temperature variable membrane, the first drainage port constituting the blood inlet end of the drainage assembly, and the second drainage port constituting the bleeding end of the drainage assembly.

[0014] Optionally, the first drainage port is provided at the lower end of the drainage tube, and the second drainage port is provided at the upper end of the drainage tube and / or on the tube wall of the upper part of the drainage tube;

[0015] When the second drainage openings are provided on the tube wall of the drainage tube, the second drainage openings are evenly distributed along the circumference of the tube wall.

[0016] Optionally, the drainage component further includes a core shaft disposed in the drainage tube, a flow channel is provided between the core shaft and the inner wall of the drainage tube, and the first drainage port is connected to the second drainage port through the flow channel.

[0017] Optionally, the upper end of the core shaft is fixedly connected to the upper part of the drainage tube, the lower end of the core shaft extends toward the first drainage port, and the cross-sectional area of ​​the core shaft decreases from the side close to the second drainage port to the side close to the first drainage port.

[0018] Optionally, the exhaust port is provided on the housing at a position higher than the effective contact height of the oxygen pressure membrane.

[0019] Optionally, the oxygenator further includes a first blocking layer and a second blocking layer provided in the outer shell, the first blocking layer being located at the top of the oxygenation temperature-variable module, and the second blocking layer being located at the bottom of the oxygenation temperature-variable module; the drainage component is connected to the blood inlet through the second blocking layer, the temperature-variable membrane is arranged around the drainage component, the inlet of the temperature-variable membrane is connected to the water inlet through the second blocking layer, and the outlet is connected to the water outlet through the second blocking layer, the first filter wraps the temperature-variable membrane, the oxygen pressure membrane is arranged around the first filter, the inlet of the oxygen pressure membrane is connected to the air inlet through the first blocking layer, and the outlet is connected to the air outlet through the second blocking layer, and the second filter wraps the oxygen pressure membrane.

[0020] Optionally, the shell includes a shell body, an upper cover provided at an open top of the shell body, and a lower cover provided at an open bottom of the shell body, the air inlet is provided on the upper cover, the blood inlet, the air outlet, the water inlet, and the water outlet are provided on the lower cover, the exhaust port is provided on the shell body near the upper cover, and the bleeding port is provided on the shell body near the lower cover;

[0021] The oxygenation temperature-variable module is arranged in the shell body, the first blocking layer is arranged between the upper end of the oxygenation temperature-variable module and the upper cover, and the second blocking layer is arranged between the lower end of the oxygenator module and the lower cover.

[0022] The implementation of the above scheme has the following beneficial effects:

[0023] The present invention provides a blood inlet at the bottom of the oxygenator and a bleeding outlet at the bottom. A drainage assembly drains blood from the blood inlet to the upper portion of the oxygenator, allowing the blood to diffuse diagonally downward through the temperature-variable membrane, the first filter, the oxygen pressure membrane, and the second filter, before exiting through the bleeding outlet at the bottom. In this blood path design, blood flows downward from the top of the oxygenator, increasing the blood flow rate. Even with the addition of the first and second filters in addition to the temperature-variable membrane and the oxygen pressure membrane, pressure loss does not increase significantly. Furthermore, the pore size of the first filter is larger than that of the second filter, and the resistance of the first filter is smaller than that of the second filter. Blood passes through the first filter before the second filter, and blood permeability is not significantly impaired.

[0024] In addition, in the prior art, oxygenator structures that only have a filter screen on the outside of the oxygen pressure membrane have a reduced permeability of blood through the oxygen pressure membrane due to large particles of impurities and bubbles mixed in the blood. Furthermore, impurities and bubbles of different sizes reach the filter screen. In order to meet the filtering requirements, the pore size of the filter screen has to be made smaller, which objectively reduces the permeability of blood through the filter screen. The present invention intercepts larger bubbles and impurities on the temperature-variable membrane side through the first filter screen, which can improve the permeability of blood through the oxygen pressure membrane, reduce the filtration pressure of the second filter screen, and improve the permeability of blood through the second filter screen. At the same time, the provision of the first filter screen and the second filter screen increases the area of ​​the filter structure, which can achieve a better filtering effect. In addition, there is no need to make the first filter screen and the second filter screen into a pleated shape that takes up a lot of space, which will not increase the internal space occupied by the oxygenator and will not increase the blood priming volume.

[0025] In summary, the present invention can achieve a better filtering effect without increasing the pressure drop and blood priming volume. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] FIG1 is a schematic structural diagram of a high-efficiency filter oxygenator disclosed in the present invention;

[0027] FIG2 is a cross-sectional view of a high efficiency filter oxygenator disclosed in the present invention;

[0028] FIG3 is a schematic diagram of the blood circuit of the high-efficiency filter oxygenator disclosed in the present invention;

[0029] FIG4 is a schematic diagram of the gas path of the high efficiency filter oxygenator disclosed in the present invention;

[0030] FIG5 is a schematic diagram of the water circuit of the high-efficiency filtration oxygenator disclosed in the present invention;

[0031] FIG6 is a schematic structural diagram of a drainage assembly of a high-efficiency filtering oxygenator disclosed in the present invention;

[0032] FIG7 is a cross-sectional view of the drainage assembly of the high efficiency filtering oxygenator disclosed in the present invention.

[0033] In the figure: 100 outer shell, 101 shell body, 102 upper cover, 103 lower cover, 104 blood inlet, 105 blood outlet, 106 water inlet, 107 water outlet, 108 air inlet, 109 air outlet, 110 exhaust outlet, 200 oxygenation temperature variable module, 201 temperature variable membrane, 202 first filter, 203 oxygen pressure membrane, 204 second filter, 205 drainage component, 206 drainage tube, 207 first drainage outlet, 208 second drainage outlet, 209 core shaft, 300 first blocking layer, 400 second blocking layer. DETAILED DESCRIPTION

[0034] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings herein can be arranged and designed in various different configurations.

[0035] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the invention as claimed, but rather merely represents selected embodiments of the present invention. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without creative effort shall fall within the scope of protection of the present invention.

[0036] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings.

[0037] In the description of the present invention, it should be noted that the terms "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings, or are the orientation or positional relationship in which the product of the invention is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0038] In the description of the present invention, it should be noted that, unless otherwise specified or limited, the terms "disposed" and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0039] In the present invention, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Furthermore, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.

[0040] The following describes embodiments of the present invention in detail. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended only to explain the present invention and are not to be construed as limiting the present invention.

[0041] This embodiment provides a high-efficiency filtered oxygenator, comprising a housing 100 and an oxygenation temperature-variable module 200 disposed within the housing 100. Referring to Figures 1-5 , the housing 100 is cylindrical, with a blood inlet 104, a water inlet 106, and a water outlet 107 disposed at the bottom thereof. The lower portion of the housing 100 is provided with an air outlet 109 and a blood outlet 105, and the upper portion of the housing 100 is provided with an air inlet 108 and an air outlet 110. The oxygenation temperature-variable module 200 is vertically arranged in the outer shell 100. The oxygenation temperature-variable module 200 includes a drainage component 205, a temperature-variable membrane 201, a first filter 202, an oxygen pressure membrane 203 and a second filter 204 from the inside to the outside. The temperature-variable membrane 201 is connected to the water inlet 106 and the water outlet 107, and the oxygen pressure membrane 203 is connected to the air inlet 108 and the air outlet 109. The blood inlet end of the drainage component 205 is connected to the blood inlet 104, and the bleeding end is located on the upper part of the temperature-variable membrane 201. The aperture of the second filter 204 is smaller than that of the first filter 202. During use, blood flows from the blood inlet 104 through the drainage component 205 to the upper part of the temperature-variable membrane 201, diffuses in all directions with the drainage component 205 as the center, and obliquely passes through the temperature-variable membrane 201, the first filter 202, the oxygen pressure membrane 203 and the second filter 204 from top to bottom, and then flows out from the bleeding port 105. The gas in the shell 100 is discharged through the exhaust port 110.

[0042] Referring to Figure 2 , the oxygenator further includes a first sealing layer 300 and a second sealing layer 400 disposed within the housing 100. The first sealing layer 300 is located at the top of the oxygenation temperature-variable module 200, and the second sealing layer 400 is located at the bottom of the oxygenation temperature-variable module 200. A drainage assembly 205 is connected to the blood inlet 104 through the second sealing layer 400. A temperature-variable membrane 201 is disposed around the drainage assembly 205. The inlet of the temperature-variable membrane 201 is connected to the water inlet 106 through the second sealing layer 400, and the outlet is connected to the water outlet 107 through the second sealing layer 400. A first filter 202 wraps around the temperature-variable membrane 201. An oxygen pressure membrane 203 is disposed around the first filter 202. The inlet of the oxygen pressure membrane 203 is connected to the air inlet 108 through the first sealing layer 300, and the outlet is connected to the air outlet 109 through the second sealing layer 400. The second filter 204 wraps around the oxygen pressure membrane 203. The first filter 202 and the second filter 204 can be flat filter structures or pleated filter structures. Of course, the flat filter structure can reduce space occupation, which is beneficial to reducing the blood pre-filling volume, while the pleated filter can increase the filtration area and improve the filtration effect. When used, you can choose one or use a combination according to your needs.

[0043] In one possible implementation, the temperature-variable membrane 201 wraps the drainage assembly 205, the first filter 202 wraps the temperature-variable membrane 201, the oxygen pressure membrane 203 wraps the first filter 202, and the second filter 204 wraps the oxygen pressure membrane 203. This design can reduce the gaps between the components, reduce the demand for internal space of the shell 100, and thereby reduce the blood priming volume.

[0044] The temperature-variable membrane 201 comprises multiple filaments distributed along the long axis of the core shaft 209. Adjacent filaments form flow gaps, forming a louver-like pattern in the radial direction of the oxygenator. The oxygen pressure membrane 203 wraps around the temperature-variable membrane 201 and comprises multiple filaments distributed and interlaced along the long axis of the core shaft 209. Adjacent filaments form flow holes, forming a honeycomb pattern in the radial direction of the oxygenator. After blood flows laterally out of the bleeding end of the drainage assembly 205, it shifts to a diagonally downward flow due to gravity and the influence of the external membrane filaments, thereby diagonally passing through the flow gaps between the filaments of the temperature-variable membrane 201. The blood flow diagonally through the oxygen pressure membrane 203 resembles a staircase, and can be divided into two states: flowing horizontally through the flow holes and flowing along the filaments of the oxygen pressure membrane 203. Specifically, because the flow slits are elongated channels and the flow holes are hole-shaped channels, after passing through the flow slits, the blood is blocked by the oxygen pressure membrane 203 and switches from a downwardly diagonal flow direction to a transverse flow direction, transversely passing through the flow holes near the temperature-variable membrane 201. Then, driven by the continued infusion of blood, the blood flows downward along the oxygen pressure membrane 203, transversely passing through the flow holes near the inner wall of the housing 100, and finally flows out of the bleeding port 105. "Transversely" means that the blood passes through the flow holes perpendicularly, that is, it flows in a radial direction relative to the oxygenator. In this state, the blood encounters less resistance, flows faster, and suffers less damage.

[0045] In one possible implementation, referring to FIG1 , the housing 100 may include a body 101, an upper cover 102, and a lower cover 103. The body 101 has openings at both the top and bottom. The upper cover 102 is located at the top opening of the body 101, and the lower cover 103 is located at the bottom opening of the body 101. A blood inlet 104, an air outlet 109, a water inlet 106, and a water outlet 107 are located on the lower cover 103. An exhaust port 110 is located on the body 101 near the upper cover 102, and a bleeding port 105 is located on the body 101 near the lower cover 103. The oxygenation and temperature-variable module 200 is disposed within the body 101. A first sealing layer 300 is disposed between the upper end of the oxygenation and temperature-variable module 200 and the upper cover 102, and a second sealing layer 400 is disposed between the lower end of the oxygenator module and the lower cover 103.

[0046] In one possible implementation, the oxygenation temperature-variable module 200 is cylindrical, and the ratio of the outer diameter of the oxygen pressure membrane 203 to its effective contact height is 1:1 to 2:1. The effective contact height of the oxygen pressure membrane 203 refers to the height of the portion of the oxygen pressure membrane 203 within the housing 101 that converts oxygen-depleted blood into oxygen-rich blood, and does not exceed the exhaust port 110. Specifically, the effective contact height of the oxygen pressure membrane 203 can be the distance between the top surface of the second sealing layer 400 and the lower end surface of the exhaust port 110.

[0047] As shown in Figure 2 , vent 110 is connected to oxygen pressure membrane 203 and is located above the effective contact height of oxygen pressure membrane 203. Bubbles that rise to the blood surface can be discharged through vent 110, but blood flowing diagonally downward will not flow out of vent 110. Positioning bleeding port 105 at the bottom of the oxygenator and vent 110 at the top allows blood to flow diagonally downward, allowing lighter bubbles to float upward, facilitating the separation of bubbles from the blood and achieving more effective bubble removal.

[0048] In one possible implementation, the pore size of the first filter 202 is 70 μm to 100 μm, and is used to intercept larger diameter particles and bubbles in the blood. The pore size of the second filter 204 is not greater than 40 μm, for example, it can be 38 μm, and the second filter 204 is used to intercept smaller diameter particles and bubbles in the blood. The present disclosure achieves two-stage filtration of blood by setting the first filter 202 and the second filter 204. When the blood obliquely passes through the temperature-variable membrane 201 and the oxygen pressure membrane 203, the larger diameter particles and bubbles are first filtered out, and only the blood and the smaller diameter particles and bubbles contained therein are allowed to reach the oxygen pressure membrane 203. The reduction of particles and bubbles allows better contact between the blood and the oxygen pressure membrane 203, which can improve the oxygenation effect; the reduction of particles and bubbles in the blood also reduces the filtration pressure of the second filter 204, which can improve the filtration effect of the second filter 204.

[0049] Referring to Figures 2 and 6 , drainage assembly 205 may include a drainage tube 206, which is provided with a first drainage port 207 and a second drainage port 208. The first drainage port 207 communicates with the blood inlet 104, and the second drainage port 208 is located above the temperature-variable membrane 201. The first drainage port 207 constitutes the blood inlet end of drainage assembly 205, while the second drainage port 208 constitutes the bleeding end of drainage assembly 205. The first drainage port 207 is located at the lower end of drainage tube 206, while the second drainage port 208 is located at the upper end of drainage tube 206 and / or on the wall of the upper portion of drainage tube 206. In one possible implementation, the second drainage port 208 is provided on the wall of the drainage tube 206, and the second drainage port 208 is evenly distributed along the circumference of the tube wall. This design allows the blood entering the drainage tube 206 to flow out in a dispersed manner around the drainage tube 206, ensuring that the blood is in full contact with the oxygen pressure membrane 203, thereby improving the utilization rate of the oxygen pressure membrane 203.

[0050] Referring to FIG7 , the drainage assembly 205 may further include a core shaft 209 disposed within the drainage tube 206. A flow passage is defined between the core shaft 209 and the inner wall of the drainage tube 206, through which the first drainage port 207 communicates with the second drainage port 208. The upper end of the core shaft 209 is fixedly connected to the upper portion of the drainage tube 206, and the lower end of the core shaft 209 extends toward the first drainage port 207. The cross-section of the core shaft 209 may be circular, elliptical, polygonal, or the like, with the cross-sectional area of ​​the core shaft 209 decreasing from the side proximal to the second drainage port 208 toward the side proximal to the first drainage port 207. In this embodiment, the core shaft 209 serves to disperse the blood. The blood enters the drainage tube 206 from the blood inlet 104, is blocked by the core shaft 209 and dispersed to the surrounding areas, then reaches the second drainage port 208 along the flow channel, and flows out from the circumferentially arranged second drainage port 208, achieving the effect of uniform diffusion from the periphery of the drainage component 205 to the temperature variable membrane 201.

[0051] This embodiment can achieve a good filtration effect without increasing the pressure drop and blood priming volume. The specific analysis is as follows:

[0052] First, blood from the blood inlet 104 is drained to the upper portion of the oxygenator through the drainage assembly 205. As the blood diffuses, it passes diagonally downward through the temperature-variable membrane 201, the first filter 202, the oxygen pressure membrane 203, and the second filter 204, before exiting the lower bleeding port 105. In this blood flow path design, blood flows downward from the upper portion of the oxygenator, increasing the blood flow rate. Even with the addition of the first and second filters 202, 204 to the temperature-variable membrane 201 and oxygen pressure membrane 203, pressure loss does not increase significantly. Furthermore, the pore size of the first filter 202 is larger than that of the second filter 204, and the resistance of the first filter 202 is lower than that of the second filter 204. Therefore, blood passes through the first filter 202 before the second filter 204, and blood flow is not significantly impaired.

[0053] Second, the first filter 202 intercepts larger bubbles and impurities on the temperature-variable membrane 201 side, which can improve the permeability of blood through the oxygen pressure membrane 203, reduce the filtration pressure of the second filter 204, and improve the permeability of blood at the second filter 204.

[0054] Third, the provision of the first filter 202 and the second filter 204 increases the area of ​​the filter structure, thereby achieving a better filtering effect. In addition, there is no need to form the first filter 202 and the second filter 204 into a pleated shape, which occupies a large space. This does not increase the internal space of the oxygenator, and therefore does not increase the blood priming volume.

[0055] Note that the above are only preferred embodiments of the present invention and the technical principles employed. Those skilled in the art will appreciate that the present invention is not limited to the specific embodiments herein, and that various obvious changes, readjustments, and substitutions are possible for those skilled in the art without departing from the scope of protection of the present invention. Therefore, although the present invention has been described in detail through the above embodiments, the present invention is not limited to the above embodiments and may include many other equivalent embodiments without departing from the scope of the present invention. The scope of the present invention is determined by the scope of the appended claims.

Claims

1. An efficient filtration oxygenator, characterized in that, Comprising: A housing (100), the bottom of the housing (100) being provided with a blood inlet (104), a water inlet (106) and a water outlet (107), the lower part of the housing (100) being provided with an air outlet (109) and a blood outlet (105), and the upper part being provided with an air inlet (108) and an exhaust port (110); An oxygenation and temperature-changing module (200), vertically arranged in the housing (100), the oxygenation and temperature-changing module (200) sequentially comprising a drainage assembly (205), a temperature-changing membrane (201), a first filter screen (202), an oxygen pressure membrane (203) and a second filter screen (204) from inside to outside. The temperature-changing membrane (201) communicates with the water inlet (106) and the water outlet (107), the oxygen pressure membrane (203) communicates with the air inlet (108) and the air outlet (109), the blood inlet end of the drainage assembly (205) communicates with the blood inlet (104), and the blood outlet end is located above the temperature-changing membrane (201). The aperture of the second filter screen (204) is smaller than that of the first filter screen (202); Blood reaches the upper part of the temperature-changing membrane (201) from the blood inlet (104) through the drainage assembly (205), diffuses around with the drainage assembly (205) as the center, and obliquely penetrates from top to bottom through the temperature-changing membrane (201), the first filter screen (202), the oxygen pressure membrane (203) and the second filter screen (204) and then flows out from the blood outlet (105). The gas in the housing (100) can be discharged through the exhaust port (110).

2. The oxygenator according to claim 1, wherein The aperture of the first filter screen (202) is 70 μm to 100 μm; the aperture of the second filter screen (204) is not greater than 40 μm.

3. The oxygenator according to claim 1, wherein The ratio of the outer diameter of the oxygen pressure membrane (203) to the effective contact height of the oxygen pressure membrane (203) is 1:1 to 2:

1.

4. The oxygenator according to claim 1, wherein The drainage assembly (205) comprises a drainage tube (206), and the drainage tube (206) is provided with a first drainage port (207) and a second drainage port (208). The first drainage port (207) communicates with the blood inlet (104), the second drainage port (208) is located above the temperature-changing membrane (201), the first drainage port (207) constitutes the blood inlet end of the drainage assembly (205), and the second drainage port (208) constitutes the blood outlet end of the drainage assembly (205).

5. The oxygenator according to claim 4, wherein The first drainage port (207) is arranged at the lower end of the drainage tube (206), and the second drainage port (208) is arranged at the upper end of the drainage tube (206) and / or on the tube wall of the upper part of the drainage tube (206); When the second drainage port (208) is arranged on the tube wall of the drainage tube (206), the second drainage ports (208) are uniformly distributed along the circumferential direction of the tube wall.

6. The oxygenator according to claim 4 or 5, characterized in that the drainage assembly (205) further includes a mandrel (209) disposed in the drainage tube (206), an overflow channel is formed between the mandrel (209) and the inner wall of the drainage tube (206), and the first drainage port (207) communicates with the second drainage port (208) through the overflow channel.

7. The oxygenator according to claim 6, characterized in that the upper end of the mandrel (209) is fixedly connected to the upper part of the drainage tube (206), the lower end of the mandrel (209) extends towards the first drainage port (207), and the cross-sectional area of the mandrel (209) decreases from the side close to the second drainage port (208) to the side close to the first drainage port (207).

8. The oxygenator according to claim 1, characterized in that the exhaust port (110) is disposed on the housing (100) at a position higher than the effective contact height of the oxygen pressure membrane (203).

9. The oxygenator according to claim 1, characterized in that the oxygenator further includes a first sealing layer (300) and a second sealing layer (400) disposed in the housing (100), the first sealing layer (300) is located at the top of the oxygen temperature-changing module (200), and the second sealing layer (400) is located at the bottom of the oxygen temperature-changing module (200); the drainage assembly (205) passes through the second sealing layer (400) and communicates with the blood inlet (104), the temperature-changing membrane (201) is disposed around the drainage assembly (205), and the inlet of the temperature-changing membrane (201) passes through the second sealing layer (400) and communicates with the water inlet (106), the outlet passes through the second sealing layer (400) and communicates with the water outlet (107), the first filter screen (202) wraps the temperature-changing membrane (201), the oxygen pressure membrane (203) is disposed around the first filter screen (202), the inlet of the oxygen pressure membrane (203) passes through the first sealing layer (300) and communicates with the air inlet (108), the outlet passes through the second sealing layer (400) and communicates with the air outlet (109), and the second filter screen (204) wraps the oxygen pressure membrane (203).

10. The oxygenator according to claim 9, characterized in that the housing (100) includes a housing body (101), an upper cover (102) disposed at the open top of the housing body (101), and a lower cover (103) disposed at the open bottom of the housing body (101), the air inlet (108) is disposed on the upper cover (102), the blood inlet (104), the air outlet (109), the water inlet (106) and the water outlet (107) are disposed on the lower cover (103), the exhaust port (110) is disposed on the housing body (101) at a position close to the upper cover (102), and the blood outlet (105) is disposed on the housing body (101) at a position close to the lower cover (103); The oxygenation and temperature-changing module (200) is disposed within the housing body (101), the first sealing layer (300) is provided between the upper end of the oxygenation and temperature-changing module (200) and the upper cover (102), and the second sealing layer (400) is provided between the lower end of the oxygenator module and the lower cover (103).

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