Herbicides and herbicide enhancer compositions and methods of use thereof

Abstract

The present disclosure provides compositions for enhancing activity of diverse chemistries with herbicidal activity. In addition, the present disclosure describes new management tools for farm operations that utilize herbicides and / or defoliants / desiccants to kill and / or dry down actively growing plant tissue. The present disclosure provides methods and compositions that enable efficient and economical farm operations typically associated with harvesting or no-till planting, and reduce active ingredients of commercial chemical herbicide products. The present disclosure describes herbicide enhancer compositions that reduce agrochemical dosage rates of conventional chemical herbicide products needed to effectively manage weeds, thereby decreasing the likelihood of resistance development in diverse plant species, while simultaneously providing an alternative, effective method for managing harvest operations and planting in major crop production systems.

Description

Attorney Docket No.278925-561797 HERBICIDES AND HERBICIDE ENHANCER COMPOSITIONS AND METHODS OF USE THEREOF CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of, and priority to, United StatesProvisional Application Serial No.63 / 565,486, filed on March 14, 2024, the contents of which are herein incorporated by reference in their entirety. SEQUENCE LISTING

[0002] This application incorporates by reference in its entirety the Sequence ListingXML entitled “278925-561797.xml” (5,651 bytes), which was created on March 11, 2025, and filed electronically herewith. TECHNICAL FIELD

[0003] New herbicides, herbicide enhancer compositions capable of enhancing theactivity of chemical herbicides, and enzyme-activated, non-selective herbicides, crop desiccants, and defoliants (enzyme-activated herbicides) are described and claimed. BACKGROUND OF THE INVENTION

[0004] To feed a growing population of 10 billion in 2050, agricultural productionwill need to increase by 70% over the next 25 years. Critical to this mission will be the development of innovative plant protection tools and strategies that help mitigate undesirable plants and plant tissues to preserve the world food supply.

[0005] The United States crop protection market reached a value of over $68 billionin 2020, with herbicides making up 58% of the products used and 382 million acres of land is used for crop production in the United States.

[0006] Chemical control of weeds is the most widespread agricultural practice in theUnited States. Weeds are the number one issue facing agricultural production and cause greater global crop losses than insects or pathogens (Oerke E C., J. Agric. Sci.144:31–43 (2006); Fried G., Chauvel B., Reynaud P. and Sache I. (2017) Decreases in Crop Production by Non-native Weeds, Pests, and Pathogens. In: Vilà M. and Hulme P., Eds., Impact of Biological Invasions on Ecosystem Services, Vol.12, Springer, Cham, 83-101. Herbicides are routinely used on more than 90% of the acreage of most U.S. crops (Gianesse LP and Sankula S., The Value of Herbicides in US Crop production, Nat’l Center for Food & 1 59768580.3Attorney Docket No.278925-561797 Agricultural Policy (NCFAP 2003), http: / / www.croplifefoundation.org; L. Gianessi and S. Sankula. Weed Technology, 21(2):559-566 (2007)). Natural weed populations in most fields are high enough to cause devastating yield losses in most crops if left (Jordan, T.N., et al., “Weed Control,” Soybeans: Improvement, Production and Uses, Second Edition, American Society of Agronomy, 1987). Loss figures between 50-90% are not uncommon for crops grown in natural weed infestations (Coble and Ritter, Weed Sci.26(6):556-59 (1978); Coble et al., Weed Sci.29(3):339-42 (1981)). If herbicide usage stopped it would result in reduced grower net income of $21 billion, or 40 % of the total net income of American farmers. There are currently no equally effective alternatives for most crops; labor cost and scarcity are the primary reasons why growers cannot substitute herbicides with sufficient hand labor to maintain yields. The Environmental Protection Agency regularly approves emergency herbicide registrations because growers cannot afford to use hand labor to remove weeds (Gianesse and Sankula (2003) and (2007)).

[0007] Organic growers cite weed control, without herbicides, as their biggestproblem. Herbicides are applied on 220 million acres of cropland, with a smaller amount—1 million acres— on organic cropland. The amount of labor necessary for a vast expansion of organic agricultural production is not available (Id.). Without herbicides, U.S. growers would no longer be able to practice no-till crop production. The abandonment of no-till farming would result in an increase of 304 billion pounds of soil erosion.

[0008] Additionally, the growing prevalence of herbicide-resistant weed populationshas increased application of chemical herbicides. In 2021, 521 unique cases of herbicide resistance have been documented throughout the world. Out of a total of 26 distinct herbicide modes of action, 23 have been compromised. (Clay, S. Agronomy, J., 113:4463–4472 (2021), incorporated by reference herein in its entirety).

[0009] The intense use of synthetic herbicides has contributed to contamination of theenvironment including soils and ground water. This damage is exacerbated by the emergence of herbicide resistant weeds that lead to cycles of increased application.

[0010] Countries around the world are increasingly restricting chemical herbicides asa method of weed control. A total of 41 countries and 25 US states have banned or restricted use of glyphosate products. In July 2023 the United States Environmental Protection Agency (EPA) released a draft strategy to reduce herbicide use and propose additional mitigations to reduce negative environmental outcomes. The European Union has a targeted reduction of 50% synthetic pesticide use by 2030. The herbicide paraquat has been banned in over 67 countries. 2 59768580.3Attorney Docket No.278925-561797

[0011] Thus, the lack of novel herbicide chemistries being brought to marketcombined with the rapid increase in multiple resistance in weeds threatens crop production worldwide (Heap, I., Pest Manag. Sci., 70(9):1306-152014 (2014).

[0012] The widely successful use of synthetic herbicides over the past 70 years hasimposed strong and widespread selection pressure, leading to the evolution of herbicide resistance in hundreds of weed species. Both target-site resistance and nontarget-site resistance mechanisms have evolved to most herbicide classes. Target-site resistance often involves mutations in genes encoding the protein targets of herbicides, affecting the binding of the herbicide either at or near catalytic domains or in regions affecting access to them. Increased amounts of protein target, by increased gene expression or by gene duplication, are an important, albeit less common, target-site mechanism. Nontarget-site resistance mechanisms include reduced absorption or translocation and increased sequestration or metabolic degradation. The mechanisms that can contribute to nontarget site resistance are complex and often involve genes that are members of large gene families. Targeted site resistance can either prevent the herbicide chemistry from interacting with the intended target (i.e. enzyme), or cause the weed to produce substantially more of the intended target, in order to avoid phytotoxicity. For example, several glyphosate-tolerant weeds contain mutations to the targeted enzyme, 5-enolpyruvylshikimate-3-phosphate synthase (ESPS), and decrease the ability of glyphosate to bind the enzyme and block its activity (Healy-Fried, M.L. et al. (2007) ‘Structural Basis of Glyphosate Tolerance Resulting from Mutations of Pro101 in Escherichia coli 5-Enolpyruvylshikimate-3-phosphate Synthase’, Journal of Biological Chemistry, 282(45), pp.32949–32955. Available at: https: / / doi.org / 10.1074 / jbc.M705624200). Alternatively, Nontargeted site mutation mechanisms involve mutations to enzymes that are not directly impacted by the herbicide mode-of-action, but which impair herbicide efficacy, either through increased metabolism of the herbicide to a non-phytotoxic molecule, or through sequestration or efflux of the phytotoxic molecule away from the intended target. For example, Nontargeted site mutation is observed in glyphosate-resistant Echinochloa colona, which increases the activity of an enzyme that pumps glyphosate out of the cell, removing the possibility of it interacting with, and thus inhibiting, ESPS (Pan, L. et al. (2021) ‘An ABCC-type transporter endowing glyphosate resistance in plants’, Proceedings of the National Academy of Sciences, 118(16), p. e2100136118. Available at: https: / / doi.org / 10.1073 / pnas.2100136118). These types of resistance mechanisms can also combine in populations producing higher levels of resistance (Gaines TA, Duke SO, Morran S, Rigon CAG, Tranel PJ, Küpper A, Dayan FE. Mechanisms 3 59768580.3Attorney Docket No.278925-561797 of evolved herbicide resistance. J Biol Chem.2020 Jul 24;295(30):10307-10330. doi: 10.1074 / jbc.REV120.013572. Epub 2020 May 19. PMID: 32430396; PMCID: PMC7383398).

[0013] Herbicide resistant is a growing problem. There are currently 534 uniquecases (species x site of action) of herbicide resistant weeds globally, with 273 species (156dicots and 117 monocots). Weeds have evolved resistance to 21 of the 31 known herbicide sites of action and to 168 different herbicides. Herbicide resistant weeds have been reported in 101 crops in 75 countries (https: / / www.weedscience.org / Pages / Species.aspx, accessed on 3 / 14 / 25).

[0014] Herbicide resistant weeds are those that can survive herbicide applications thatwould normally kill sensitive weeds, and the degree of sensitivity varies depending on the herbicide and the weed species. Herbicide resistance is therefore also the degree of sensitivity that a population has and resistant weed populations are no longer sensitive to an herbicide dose that would previously kill the population (S.Z. Knezevic et al., 2017, Encyclopedia of Applied Plant Sciences, 2nd Eds, Vol 3, Crop Systems; Herbicide Resistance and Molecular Aspects).

[0015] The economic impact of resistant weeds is in the billions of dollars (Clay S A.Near-term challenges for global agriculture: Herbicide-resistant weeds. Agronomy Journal. 2021; 113: 4463–4472. https: / / doi.org / 10.1002 / agj2.20749). In 2011, it was estimated that resistant weeds in Tennessee soybean [Glycine max (L.) Merr.] increased herbicide costs by about US$40 ha−1and yield loss by 17%, which added up to about US$104 million for that year and area alone (Steckel, B. H. (2011). Herbicide resistant weeds cost farmers millions. FarmProgress. https: / / www.farmprogress.com / soybeans / herbicide-resistant-weeds-cost- farmers-millions). In Canada between 2014 and 2017, the estimated monetary impact of herbicide-resistant weeds in the Canadian Prairies was $530 million CAD annually (Beckie, Hugh J., et al. "Herbicide-resistant weeds in the Canadian prairies: 2012 to 2017." Weed Technology 34.3 (2020): 461-474). The estimated annual cost of resistance in England is £400M in lost gross profit (2014 prices) and annual wheat yield loss due to resistance is 0.8 million tonnes. A total loss of herbicide control against black-grass would cost £1 billion and 3.4 million tonnes of lost wheat yield annually (Varah, A., Ahodo, K., Coutts, S.R. et al. Thecosts of human-induced evolution in an agricultural system. Nat Sustain 3, 63–71 (2020).https: / / doi.org / 10.1038 / s41893-019-0450-8).

[0016] Herbicide resistant weeds are those that can survive herbicide applications thatwould normally kill susceptible weeds, and the degree of susceptibility varies depending on 4 59768580.3Attorney Docket No.278925-561797 the herbicide and the weed species. Herbicide resistance is therefore also the degree of susceptibility that a population has and resistant weed populations are no longer susceptible to an herbicide dose that would previously kill the population (S.Z. Knezevic et al., 2017, Encyclopedia of Applied Plant Sciences, 2nd Eds, Vol 3, Crop Systems; Herbicide Resistance and Molecular Aspects). SUMMARY OF THE INVENTION

[0017] The present disclosure describes an herbicide enhancer compositioncomprising an iodide salt and a thiocyanate salt.

[0018] In addition, the present disclosure describes a herbicidal combinationcomposition comprising: (A) an herbicide enhancer composition as described herein, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a synergistic weight ratio, as defined by the Colby Formula.

[0019] In addition, the present disclosure provides a method of enhancing the efficacyof a chemical herbicide, or an agriculturally acceptable salt thereof, in a plant field, comprising the step of administering said chemical herbicide, or an agriculturally acceptable salt thereof with an enhancer composition of the present disclosure, to a target plant in said plant field; wherein said enhancer composition comprises an iodide salt and a thiocyanate salt; wherein said enhancer composition increases the absorption of said chemical herbicide, or an agriculturally acceptable salt thereof, into said target plant or wherein said enhancer composition increases the translocation of said chemical herbicide, or an agriculturally acceptable salt thereof, within said target plant; wherein said enhancer composition alone has between about 0% and about 5%, preferably between about 0% and about 1% herbicide activity when compared to the combination of said chemical herbicide, or an agriculturally acceptable salt thereof and said enhancer composition.

[0020] In addition, the present disclosure provides a method of controlling unwantedplant growth comprising: applying a herbicidally effective amount of a herbicidal combination composition as described herein, or agrochemically acceptable salts thereof, to an unwanted plant or to the locus thereof.

[0021] In addition, the present disclosure provides a method of manufacturing anenzyme-free enhanced herbicidal combination composition, comprising: a) immobilizing an H2O2-producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b) exposing said immobilized H2O2-producing and free radical producing (FRP) enzymes to 5 59768580.3Attorney Docket No.278925-561797 a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2- producing enzyme; c) collecting a product solution, wherein said product solution comprises reactive oxidative species; and d) combining said product solution with a chemical herbicide.

[0022] In addition, the present disclosure describes a composition comprisinghydrogen peroxide and an iodide salt, wherein said composition is optimized to be a broad- spectrum and non-selective herbicide, defoliant, or plant desiccant.

[0023] In addition, the present disclosure provides a method of deploying anherbicide, comprising the step of administering a composition of present disclosure to a plant.

[0024] In addition, the present disclosure provides a method of deploying a plantdefoliant, comprising the step of administering a composition of the present disclosure to a plant.

[0025] In addition, the present disclosure provides a method of deploying a plantdesiccant, comprising the step of administering a composition of the present disclosure to a plant.

[0026] In addition, the present disclosure provides a method of manufacturing anenzyme-free herbicidal combination composition, comprising: a. immobilizing an H2O2- producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b. exposing said immobilized H2O2-producing and free radical producing (FRP) enzymes to a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2- producing enzyme; and c. collecting a product solution, wherein said product solution comprises reactive oxidative species.

[0027] In addition, the present disclosure provides a method of manufacturing anherbicidal combination composition, comprising: a) placing an H2O2-producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b) exposing said H2O2- producing and free radical producing (FRP) enzymes to a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2-producing enzyme; and c) collecting a product solution, wherein said product solution comprises reactive oxidative species. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1A. The glucose oxidase (GOx) system for producing reactiveoxidative species that cause plant injury.

[0029] Figure 1B. The glucose oxidase (GOx) lactoperoxidase (LP) GOx / LP systemfor producing reactive oxidative species that cause plant injury. 6 59768580.3Attorney Docket No.278925-561797

[0030] Figure 2A. Process flow diagram depicting the in-flow enzymeimmobilization process on scaffold materials inside a packed bed reactor using recirculation.

[0031] Figure 2B. Process flow diagram that produces an enzyme-free herbicide. Apressurized biocatalytic packed bed flow reactor uses the two-enzyme system of glucose oxidase and lactoperoxidase along with a feed comprising about 35 mM KI, 8 mM KSCN, 300 mM glucose and 200 mM sodium acetate at pH 5.5.

[0032] Figure 3A. Herbicidal activity of the ZX formulation 35 mM KI and 8 mMKSCN at a pH of 4.5. Four droplets of 50 µL were applied to detached leaves of different plant species to observe herbicidal activity of ZX. Figure 3B shows the effect of raising the pH to 5.2 on the herbicidal activity of the ZX formulation.

[0033] Figure 4A. Snap bean injury was measured by Normalized DifferenceVegetative Index (NDVI) after applications of two ZX formulations (ZX1 = 35 mM, KI / 8 mM KSCN and ZX2 = 18 mM KI, 4 mM KSCN). A non-treated control was included and a fungicide, Topsin, was used to control plant diseases.

[0034] Figure 4B. The percent soybean crop injury after application of 2 mL of ZX2on an intact whole plant in the laboratory.

[0035] Figures 4C and 4D. Snap bean injury after applications of ZX to snap beanplots in the field. ZX formulations ZX1 and ZX2. Figure 4C shows the plants 3 days post application. Figure 4D shows the plants 1 week post application.

[0036] Figure 5. Tomato crop injury after application of 10 mL of ZX formulationsconsisting of either 80 mM KI or 80 mM KSCN on whole tomato plants.

[0037] Figure 6. ZX1 sprayed at a rate of 50 gallons per acre (gpa) to snap beans.The plants were evaluated by percent crop injury. The formulation was sprayed 23 days post planting and evaluated 36 days post planting. The snap beans had 75% plant injury.

[0038] Figure 7. A small plot field trial was used to evaluate the greater than additiveeffect of EX1 herbicide enhancer with diverse herbicide chemistries for control of broadleaf weeds. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control. These data show percent control of broadleaf weeds 3 weeks after application of the EX1 and herbicide combinations or herbicides applied alone. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0039] Figure 8. A small plot field trial was used to evaluate the greater than additiveeffect of EX1 herbicide enhancer with diverse herbicide chemistries for control of grass 7 59768580.3Attorney Docket No.278925-561797 weeds. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. These data show percent control of grass weeds, 3 weeks after the application of the EX1 and herbicide combinations or herbicides applied alone. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0040] Figure 9. A small plot field trial was used to evaluate the greater than additiveeffect of EX2 herbicide enhancer with diverse herbicide chemistries for control of broadleaf weeds in Whitakers, NC., USA in 2023. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0041] Figure 10. A small plot field trial was used to evaluate the greater thanadditive effect of EX2 herbicide enhancer with diverse herbicide chemistries for control of grass weeds. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0042] Figure 11. A greenhouse trial was used to evaluate the greater than additiveeffect of EX3 and EX4 when combined with two application rates of the herbicide glufosinate on the control of pigweed (Amaranthus retroflexus) and velvetleaf (Abutilon theophrasti). Potted weeds were rated for plant injury, 3 weeks after herbicide application, and reported as percent weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0043] Figure 12. A greenhouse trial was used to evaluate the greater than additiveeffect of two EX formulations (EX3 and EX4) when combined with two application rates of the herbicide glufosinate on ragweed (Ambrosia artemisiifolia) and clover (Trifolium repens). Potted weeds were rated for plant injury, 3 weeks after herbicide application, and reported as percent weed control from 0-100, where 0% = no weed control and 100% = complete control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. 8 59768580.3Attorney Docket No.278925-561797

[0044] Figure 13. A greenhouse trial was used to evaluate the greater than additiveeffect of two EX formulations (EX3 and EX4) when combined with two application rates of the herbicide glufosinate on crabgrass (Digitaria ischaemum) and signal grass (Brachiaria platyphilla). Potted weeds were rated for plant injury, 3 weeks after herbicide application, and reported as percent weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0045] Figure 14. A small plot field trial was used to evaluate the greater thanadditive effect of EX5 herbicide enhancer with the herbicide glufosinate for control of large (4-8 inches) broadleaf weeds. EX5 was applied by itself, together with five application rates of glufosinate, or glufosinate was applied alone at equivalent rates. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0046] Figure 15. A small plot field trial was used to evaluate the greater thanadditive effect of EX5 herbicide enhancer with the herbicide glufosinate for control of grass weeds. EX5 and was applied alone, or combined with five application rates of glufosinate. Glufosinate was also applied alone at the same five application rates evaluated with EX5. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0047] Figure 16. A small plot field trial was used to evaluate the greater thanadditive effect of EX5 herbicide enhancer with the herbicide glufosinate for control of emerging (2-4 inches) broadleaf weeds. EX5 and was applied alone and combined with five application rates of glufosinate. Glufosinate was also applied alone at the same five application rates evaluated with EX5. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0048] Figure 17. A small plot field trial was used to evaluate the greater thanadditive effect of EX6 and EX7 herbicide enhancers, with the herbicide glufosinate, for 9 59768580.3Attorney Docket No.278925-561797 control of emerging (2-4 inches) broadleaf weeds. EX6 and EX7 were applied with glufosinate , or glufosinate was applied alone 16 g ai / acre. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0049] Figures 18A and 18B. A small plot field trial was used to evaluate the greaterthan additive effect of EX1and EX8 herbicide enhancers with the herbicide glufosinate for overall weed control. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent total weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0050] Figure 19. A small plot field trial was used to evaluate the greater thanadditive effect of EX3 and EX4 with the herbicide glufosinate for control of broadleaf weeds. EX3 and EX4 were applied alone, or combined with two glufosinate application rates. Glufosinate was also applied alone at the same two application rates. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent broadleaf weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0051] Figure 20. A small plot field trial was used to evaluate the greater thanadditive effect of EX3 and EX4 with two application rates of the herbicide glufosinate for control of grass weeds. EX3 and EX4 were applied alone, or combined with two rates of glufosinate. Glufosinate was also applied alone at the same rates. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0052] Figure 21. Glufosinate translocation was evaluated using the EX37 herbicideenhancer formulation with two rates of glufosinate herbicide in six-week-old, greenhouse- grown annual ryegrass (Lolium multiflorum) in Ithaca, NY, USA in 2024. Translocation was visually determined by the progressive yellowing of the leaf blade, due to glufosinate herbicide movement,10 days after application of 15 µL droplets to ryegrass leaf blades. 10 59768580.3Attorney Docket No.278925-561797

[0053] Figure 22. Enhancement of glufosinate translocation by EX14 was evaluatedusing herbicide enhancer formulation EX14, with two rates of glufosinate herbicide in field grown goldenrod (Solidago sp.) in Freeville, NY, USA in 2024. Translocation was determined by visual assessment of meristem death, 12 days after application of 20 µL droplets of the listed treatment to distal goldenrod leaves. Translocation was determined by meristem death due to glufosinate herbicide movement.

[0054] Figure 23. Enhancement of glufosinate translocation by EX14 was evaluatedusing herbicide enhancer formulation EX14, with two rates of glufosinate herbicide in field grown goldenrod (Solidago sp.) in Freeville, NY, USA in 2024. Translocation was determined by visual assessment of meristem death, 12 days after application of 20 µL droplets of the listed treatments to distal goldenrod leaves. Translocation was quantified by counting the number of plants, in each treatment, with dead meristems.

[0055] Figure 24. A small plot field trial was used to evaluate the greater thanadditive effect of EX20 herbicide enhancer with glufosinate herbicides—Interline, Reckon and Liberty—at 4 discrete rates of glufosinate for control of yellow nutsedge (Cyperus esculentus) in Freeville, NY, USA in 2024. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent weed control from 0-100, where 0% = no weed control and 100% = complete weed control.

[0056] Figure 25. A small plot field trial was used to evaluate the greater thanadditive effect of EX20 herbicide enhancer with glufosinate herbicides—Interline, Reckon and Liberty—at multiple rates for total weed control in Freeville, NY, USA in 2024. Plots were rated for plant injury, 3 weeks after herbicide application, and reported as percent weed control from 0-100, where 0% = no weed control and 100% = complete weed control.

[0057] Figure 26. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on total weed control, in an over-the-top application of genetically-modified, multiple herbicide-resistant corn. The applications of two herbicides were made at a the recommended label rate of 266 g ai / A for Liberty and 431 g ai / A for Enlist One. Plots were rated for total plant injury, 3 weeks after herbicide application, and reported as percent total weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0058] Figure 27. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on grass 11 59768580.3Attorney Docket No.278925-561797 weed control, in an over-the-top application of genetically-modified, multiple herbicide- resistant corn. The application of two herbicides were made at the recommended label rate of 266 g ai / acre for Liberty and 431 g ai / acre for Enlist One. Plots were rated for grass injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0059] Figure 28. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on total weed control, in an over-the-top application of genetically-modified, multiple herbicide-resistant soybean. The application of two herbicides were made at the recommended label rate of 266 g ai / A for Liberty and 431 g ai / A for Enlist One. Plots were rated for total plant injury, 3 weeks after herbicide application, and reported as percent total weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0060] Figure 29. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on grass weed control, in an over-the-top application of genetically-modified, multiple herbicide- resistant soybean. The application of two herbicides were made at the recommended label rate of 266 g ai / A for Liberty and 431 g ai / A for Enlist One. Plots were rated for grass injury, 3 weeks after herbicide application, and reported as percent grass weed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0061] Figure 30. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on ragweed (Ambrosia artemisiifolia) control, in an over-the-top application of genetically-modified, multiple herbicide-resistant soybean. The applications of two herbicides were made at the recommended label rate of 266 g ai / A for Liberty and 431 g ai / A for Enlist One. Plots were rated for ragweed injury, 3 weeks after herbicide application, and reported as percent ragweed control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. 12 59768580.3Attorney Docket No.278925-561797

[0062] Figure 31. A small plot field trial was conducted in Aurora NY, USA in 2024,to evaluate the greater than additive effect of EX15 with Liberty and Enlist One on lambsquarter (Chenopodium album) control, in an over-the-top application of genetically- modified, multiple herbicide-resistant soybean. The application of two herbicides were made at the recommended label rate of 266 g ai / A for Liberty and 431 g ai / A for Enlist One. Plots were rated for lambsquarters injury, 3 weeks after herbicide application, and reported as percent control from 0-100, where 0% = no weed control and 100% = complete weed control. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0063] Figure 32. The effect of Botanical KleenUp 3% (v / v) active ingredientcombined with enhancer formulation EX15, or Botanical KleenUp 3% (v / v) active ingredient alone was measured. Plants were rated for plant injury, 15 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead.

[0064] Figure 33. Translocation of 2,4-D translocation was measured using herbicideenhancer formulation EX17 with two rates of 2,4-D herbicide in field-grown Smartweed (Polygonum pensylvanicum) in Ithaca, NY, USA in 2024. Translocation was visualized by applying 20 µl droplets to Smartweed leaves and total plant biomass was measured. Weights were taken 15 days post treatment. Data from the last rating (percent injury) were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences, Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0065] Figure 34. Translocation of 2,4-D (Clean Amine) was measured usingherbicide enhancer formulation EX17 with two rates of 2,4-D herbicide in field-grown Smartweed (Polygonum pensylvanicum) in Ithaca, NY, USA in 2024. Translocation was visualized by applying 20 µL droplets to Smartweed leaves and total plant height was measured. Measurements were taken 15 days post treatment. Data from the last rating (height) were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different.

[0066] Figure 35. Glufosinate translocation was evaluated using herbicide enhancerformulation EX23 with 266 g ai / acre of glufosinate using greenhouse-grown lambsquarters (Chenopodium album) in Ithaca, NY, USA in 2024. Translocation was assessed by applying 2, 10 µL droplets to mature, fully-expanded lambsquarters leaves and imaging the growth of 13 59768580.3Attorney Docket No.278925-561797 emerging leaf tissue. Translocation was determined by the damage to the new, developing leaves.

[0067] Figure 36. Glufosinate translocation was evaluated using herbicide enhancerformulation EX23 with 266 g ai / acre of glufosinate using greenhouse-grown lambsquarters (Chenopodium album) in Ithaca, NY, USA in 2024. Translocation was assessed by applying 2, 10 µL droplets to mature, fully-expanded lambsquarters leaves and imaging the growth of emerging leaf tissue. Translocation was determined by the damage observed to the new developing leaves.

[0068] Figure 37 A and B. 2,4-D enhancement was measured using herbicideenhancer formulation EX15 with 2,4-D Clean Amine herbicide at 32 fl oz / acre, applied to six-week-old, greenhouse-grown annual ryegrass (Lolium multiflorum) plants in Ithaca, NY, USA in 2024. Plants were rated for plant injury, 10 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead.

[0069] Figure 38. The effect of hydrogen peroxide (H2O2) combined with EX22 withno added glucose oxidase (GOx) was measured using greenhouse-grown red root pigweed Amaranthus retroflexus (at the 4 leaf stage), in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 15 days after herbicide application, and reported as percent injury from 0- 100, where 0% = no injury and 100% = dead. These data show that EX supplemented with hydrogen peroxide and glufosinate as well as glufosinate alone do not control ryegrass better than EX using GOx to make hydrogen peroxide and that higher plant injury results from the use of the entire EX system, inclusive of the iodide salt, thiocyanate salt, glucose, glucose oxidase and a peroxidase, for example, lactoperoxidase. This data also shows that inclusion of GOx enhances the control of grasses.

[0070] Figure 39. The effect of hydrogen peroxide (H2O2) combined with EX22 withor without glucose oxidase (GOx) was measured using greenhouse-grown annual ryegrass (Lolium multiflorum), in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 15 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data from the last rating (percent injury) were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that adding hydrogen peroxide to Liberty does not increase plant injury, whereas EX22 and Liberty did increase plant injury, when compared to Liberty applied alone. 14 59768580.3Attorney Docket No.278925-561797

[0071] Figure 40. The effect of EX15 and glufosinate at 66 g ai / acre was comparedwith glufosinate at 66 g ai / acre + KSCN at 15 mM and using greenhouse-grown radish plants (Raphanus sativus), in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 15 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that adding 15 mM KSCN to glufosinate is not as effective as the EX15 (with 15 mM KSCN) formulation in causing plant injury.

[0072] Figure 41. The control of greenhouse-grown radish (Raphanus sativus) plantstreated with EX41 and glufosinate at 186 g ai / acre, or with glufosinate at 186 g ai / acre and KSCN at final molar concentrations of 10 mM, 5 mM, and 1 mM KSCN, in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 21 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that EX41 was more effective in causing plant injury when compared to glufosinate with added KSCN.

[0073] Figure 42. The control of greenhouse-grown radish (Raphanus sativus) plantstreated with EX41 and Glufosinate at 186 g ai / acre, or with Glufosinate at 186 g ai / acre and KSCN at final molar concentrations of 10 mM, 5 mM, and 1 mM KSCN, in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 15 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that EX41 was more effective in causing plant injury when compared to glufosinate with added KSCN.

[0074] Figure 43. The control of greenhouse-grown, glyphosate and glufosinate-resistant palmer amaranth (Amaranthus palmeri) treated with EX15 and Roundup PowerMaxIII at 24 oz / acre, EX15 + Glufosinate at 200 g ai / acre, Roundup PowerMaxIII at 24 oz / acre, or Glufosinate at 200 g ai / acre in Fayetteville, Arkansas USA in 2025. Plants were rated for plant injury, 21 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s 15 59768580.3Attorney Docket No.278925-561797 HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that combinations of EX15 and Liberty, or EX15 and Roundup PowerMaxIII increases plant injury when compared to either product applied alone.

[0075] Figure 44. The control of greenhouse-grown, glyphosate-resistant waterhemp(Amaranthus tuberculatus) plants treated with EX15 and glufosinate at 266 g ai / acre, or glufosinate at 266 g ai / acre in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 21 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. These data show that EX15 combined with glufosinate at 266 g ai / acre caused significantly more injury than an application of glufosinate alone at the same rate.

[0076] Figure 45. The control of greenhouse-grown radish (Raphanus sativus) plantstreated with EX15, at multiple application rates (grams / acre), combined with glufosinate at 266 g ai / acre, compared with glufosinate applied alone at 266 g ai / acre in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 5 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. Data were analyzed with the statistical program JMP-SAS (Carey, NC) for analysis of variance and significant differences. Tukey’s HSD was used to assess multiple comparison of means (0.05). Treatments with the same letter are not significantly different. This data shows that there is a linear dose response with EX concentrations and that each EX dose showed a greater than additive effect with glufosinate compared to glufosinate alone, with the 1X EX15, 1362 g / acre, having the highest additive effect, for example, if using the Colby Formula, among other methods for determining greater than additive or synergistic effects.

[0077] Figure 46. The control of greenhouse-grown lambsquarters (Chenopodiumalbum) treated with EX15 and Tahoe3A at 170 g ai / acre, EX15 and Clarity at 71 g ai / acre, Tahoe3A at 170 g ai / acre, or Clarity at 71 g ai / acre in Ithaca, NY, USA in 2025. Plants were weighed, 21 days after herbicide application, for plant growth in response to spray application of the different treatments and reported as weight in grams. These data show that EX15, when combined with Tahoe3A and Clarity, caused 51% and 54% reduction in plant growth, respectively, compared to the products applied alone.

[0078] Figure 47. The control of greenhouse-grown annual ryegrass (Loliummultiflorum) under low temperature. Annual ryegrass was treated with a combination of 16 59768580.3Attorney Docket No.278925-561797 EX15 and glufosinate, or glufosinate alone, at multiple glufosinate application rates at 10°C, in College Park, PA, USA in 2025. Glufosinate rates used were 90 g ai / acre, 179 g ai / acre, and 358 g ai / acre. Treated plants were stored at 10°C after treatment and biomass was recorded 21 days after application. This experiment demonstrates that EX15 enhanced glufosinate efficacy by nearly 3-fold when Italian ryegrass was placed under suboptimal temperature conditions.

[0079] Figure 48. The control of greenhouse-grown annual ryegrass (Loliummultiflorum) treated with dicamba (Clarity) at 142 g ai / acre, or with dicamba at 142 g ai / acre and 40 mM KSCN, in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 14 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. These data show that the addition of 40 mM KSCN does not increase plant injury when compared to the application of Clarity alone at that rate.

[0080] Figure 49. The control of greenhouse-grown radish (Raphanus sativus) plantstreated with EX15 combined with glufosinate at 266 g ai / acre, 0.5 mM KI and glufosinate at 266 g ai / acre, 15 KSCN and glufosinate at 266 g ai / acre, 0.5 / 15 mM KI / KSCN and glufosinate at 266 g ai / acre, and glufosinate applied alone at 266 g ai / acre in Ithaca, NY, USA in 2025. Plants were rated for plant injury, 5 days after herbicide application, and reported as percent injury from 0-100, where 0% = no injury and 100% = dead. These data show that full EX system, not just the individual components, are required to have a greater than additive effect with glufosinate, compared to glufosinate alone. DETAILED DESCRIPTION OF THE INVENTION

[0081] DEFINITIONS

[0082] “Affect” refers to how a something influences another thing, e.g., how achemical compound, herbicide, chemical herbicide, herbicide enhancer, and the like influences a plant.

[0083] “Agronomically acceptable carrier” or “agriculturally acceptable carrier”covers all adjuvants, inert components, dispersants, surfactants, tackifiers, binders, etc. that are ordinarily used in pesticide or herbicide formulation technology; these are well known to those skilled in pesticide or herbicide formulation.

[0084] “Agronomically acceptable salt” or “agriculturally acceptable salt” issynonymous with pharmaceutically acceptable salt, and as used herein refers to a compound that is modified by making acid or base salts thereof. In some embodiments, agronomically acceptable salts, hydrates, solvates, crystal forms and individual isomers, enantiomers, 17 59768580.3Attorney Docket No.278925-561797 tautomers, diastereomers and prodrugs of herbicides, chemical herbicides, or herbicide enhancers described herein can be utilized. Non-limiting examples of agronomically acceptable salts include: acid addition salts, formed with inorganic acids; acid addition salts formed with organic acids; or salts formed when an acidic proton present in the parent compound is replaced by a metal ion, e.g., an alkali metal ion, aluminum ion; or coordinates with an organic base such as ethanolamine, and the like. Other non-limiting examples of agronomically acceptable salts include: hydrochloride; sodium; sulfate; acetate; phosphate or diphosphate; chloride; potassium; maleate; calcium; citrate; mesylate; nitrate; tartrate; aluminum; gluconate; any organic or inorganic addition salt; alkali metal salts (sodium salts, potassium salts, etc.); alkaline earth metal salts (calcium salts, magnesium salts, etc.); salts derived from inorganic or organic bases (e.g., sodium, potassium, lithium, ammonium, calcium, magnesium, ferrous, zinc, copper, manganous, aluminum, ferric, manganic salts, isopropylamine, diethylamine, ethanolamine, piperidine, tromethamine, choline, and the like).

[0085] “Applying” or “application” or “apply” or “administering” or “administration”or “administer” or “deploy” or “deploying” means to dispense and / or otherwise provide, and refers to any method of application or route of administration, to an unwanted plant, or a part thereof, or a locus thereof, for example, a plant, a weed, a crop of a locus of all of the foregoing. For example, applying can refer to, e.g., application of a herbicidal combination composition containing an herbicide enhancer composition and one or more chemical herbicides or agronomically acceptable salts thereof, as a combination in separate compositions, a mixture, or all combined in a single composition, further comprising one or more adjuvants, excipients, diluents or carriers, e.g., a sprayable composition, a foam, a burning formulation, a powder, granules, particles, microgranules, dusts, and other known agriculturally acceptable formulations for herbicidal treatments, including a surface- treatment, a dispersant, a microencapsulation, and the like. By “co-application” or “co- administer,” it is meant that two or more components are applied or administered at the same time, or one or more components are applied or administered just prior to, or just after the application of the other one or more components.

[0086] “Chemical herbicide” refers to a synthetic or naturally occurring chemicalcompound used to function as an herbicide. For example, in some embodiments, examples of chemical herbicides include, without limitation: glufosinate, glufosinate-ammonium, L- glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, 18 59768580.3Attorney Docket No.278925-561797 dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, and trifludimoxazin.

[0087] In some embodiments, additional examples of chemical herbicides include,without limitation: glufosinate-ammonium or glufosinate-P-ammonium or 2-amino-4- (hydroxymethylphosphinyl) butanoic acid-monoammonium salt; diglycolamine salt of dicamba or benzoic acid, 3,6-dichloro-2-methoxy-, compound with 2-(2-aminoethoxy) ethanol (1:1); triclopyr or (3,5,6-trichloro-2-pyridinyl)oxyacetic acid, triethylamine salt; carfentrazone-ethyl or ethyl (RS)-2-chloro-3-[2-chloro-5-(4-difluoromethyl-4,5-dihydro-3- methyl-5-oxo-1H-1,2,4-triazol-1-yl)-4-fluorophyenyl]proprionate; flumioxazin or N-(7- fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2- dicarboxamide; sulfentrazone or 2′,4′-dichloro-5′-(4-difluoromethyl-4,5-dihydro-3-methyl-5- oxo-1H-1,2,4-triazol-1-yl) methanesulfonanilide; paraquat or 1,1'-Dimethyl-4,4'-bipyridinium dichloride; glufosinate ammonium or 2-amino-4-[hydroxy(methyl)phosphoryl]butanoate; 2,4- dichlorophenoxyacetic acid, choline salt or 2-(2,4-dichlorophenoxy)acetate;2- hydroxyethyl(trimethyl)azanium; chlorothalonil or 2,4,5,6-tetrachlorobenzene-1,3- dicarbonitrile; spinetoram or 3'-ethyl-5,6-dihydrospinosyn J and 3'-ethoxy-spinosyn L; pyraclostrobin or carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3- yl]oxy]methyl]phenyl]methoxy-, methyl ester; glyphosate or N-(phosphonomethyl)glycine potassium salt; and diglycolamine salt of 3,6-dichloro-o-anisic acid.

[0088] “Colby Formula” refers to a formula used to predict the combinedeffectiveness or efficacy of two compounds when they are combined to determine, for example, if there is a greater than additive, additive, or reductive effect between two compounds for a given compound activity (Colby, S. R., Calculating synergistic and antagonistic responses of herbicide combination, Weeds, Vol.15, pages 20-22; 1967). The Colby Formula can be calculated as follows: ppm = milligrams of active ingredient (a.i.) per liter X = % action by first active ingredient using p ppm of the active ingredient Y = % action by second active ingredient using q ppm of the active ingredient. 19 59768580.3Attorney Docket No.278925-561797 According to Colby, the expected action of active ingredients A + B using p + q ppm of active ingredient is represented by the following formula: E = X + Y – ((X * Y) / 100). If the action actually observed (O) is greater than the expected action E then the action of the combination is greater than additive. In mathematical terms, a greater than additive effect corresponds to a positive value for the difference of (O – E). In the case of purely complementary addition of activities (expected activity), said difference (O – E) is zero. A negative value of said difference (O – E) signals a loss of activity compared to the expected activity.

[0089] “Combination” refers to the result of combining two or more separatecomponents (e.g., a first component and one or more additional components). Thus, as used herein, a “combination” refers to an association of two or more separate components.

[0090] In some embodiments, a combination can be a “mixture.” For example, insome embodiments, a mixture refers to a combination of a first component, and one or more additional components, wherein the first component and the one or more additional components are present together in a single entity (e.g., a single unit). Thus, in some embodiments, a mixture can comprise a first component, and one or more additional components, wherein the first component and the one or more additional components are present in admixture for simultaneous administration.

[0091] In some embodiments, a combination can comprise a first component, and oneor more additional components, wherein the first component and the one or more additional components, are present separately (e.g., more than one unit). For example, in some embodiments, a combination can comprise a first component, and one or more additional components, wherein the first component and the one or more additional components may be administered separately, sequentially, simultaneously, concurrently or chronologically staggered.

[0092] In some embodiments, a combination can refer to the separate, sequential,simultaneous, concurrent or chronologically-staggered application of two or more separate components. For example, in some embodiments, a “combination” refers to the result of a simultaneous application of both a first component, and one or more additional components. In another embodiment, a “combination” refers to the result of a separate application of a first component, and one or more additional components. In further embodiments, a “combination” refers to the result of a sequential application of two or more separate components, e.g., a first application of a first component, followed by a second application of one or more additional components, or vice versa. Where the application is sequential or 20 59768580.3Attorney Docket No.278925-561797 separate, the delay in applying the second component should not be such as to lose the beneficial effect of the combination.

[0093] “Composition” refers to various mixtures or combinations of components (A)and (B), for example, in a single “ready-mix” form, in a combined spray mixture composed from separate formulations of the single active ingredient components, such as a “tank-mix”, and in a combined use of the single active ingredients when applied in a sequential manner, i.e., one after the other with a reasonably short period, such as a few hours or days. The order of applying the components (A) and (B) is not essential for working the present disclosure.

[0094] “Crop” refers to a plant or group of plants that are cultivated for economic,agricultural, or commercial purposes. Accordingly, a “crop plant” refers to plant that is desired in a particular area, and which can be cultivated for economic, agricultural, or commercial purposes. Nonlimiting examples of what crops can include are plants grown for food, fiber, medicinal purposes, or other raw materials.

[0095] “Crop field” refers to an area or environment where crops are cultivated orgrown.

[0096] “Crop is resistant” or “crop resistance” refers to the ability of a crop plant towithstand or tolerate specific stresses or threats that could otherwise negatively impact its growth, development, or yield. For instance, crop resistance can be naturally selected, cross bred, or genetically engineered or modified in a crop plant for said crop plant to be resistant to certain herbicides.

[0097] “Defoliant” refers to a compound that induces premature leaf loss orabscission in plants by altering physiological processes that regulate leaf retention.

[0098] “"Desiccant” refers to a compound that induces the rapid drying or moistureremoval from plant tissues, for instance by drawing water out of the plant cells and tissues.

[0099] “EC50” or “EC50” refers to half-maximal effective concentration, which is ameasurement of how much of an agent is needed to have a given effect on a biological process by half, thus providing a measure of potency of said agent.

[0100] “Excipient” refers to any agronomically, agriculturally, or pharmaceuticallyacceptable additive, carrier, surfactant, emulsifier, thickener, preservative, solvent, disintegrant, glidant, lubricant, diluent, filler, bulking agent, binder, emollient, stiffening agent, chelating agent, stabilizer, solubilizing agents, dispersing agent, suspending agent, antioxidant, antiseptic, wetting agent, humectant, fragrant, suspending agents, pigments, colorants, isotonic agents, viscosity enhancing agents, mucoadhesive agents, and / or any combination thereof, that can be added to an agronomical or agricultural composition, 21 59768580.3Attorney Docket No.278925-561797 preparation, and / or formulation, which may be useful in achieving a desired modification to the characteristics of the agronomical or agricultural composition, preparation, and / or formulation. Such modifications include, but are not limited to, physical stability, chemical stability, pesticidal or herbicidal efficacy, and / or any combination thereof.

[0101] “Farm” refers to an area or environment that is used for the cultivation orgrowth of crops. A farm can be on land or within or on top of buildings or structures, and can be outdoors or indoors / enclosed from the outdoor environment.

[0102] “Glucose oxidase” (GOx) refers to an enzyme that catalyzes the oxidation ofglucose into gluconic acid and hydrogen peroxide (H2O2). It is a hydrogen peroxide- producing (HPP) enzyme. Nonlimiting examples of sources of glucose oxidase include members of the genera Aspergillus and Penicillium.

[0103] “Glufosinate”, also known as phosphinothricin, refers to a naturally occurring,non-selective, systemic, broad-spectrum herbicide. Its chemical name is 2-amino-4- [hydroxy(methyl)phosphoryl]butanoic acid.

[0104] “Genetically modified organism” or “GMO” or “genetically modified” or“GM” refers to an organism whose genetic characteristics have been altered by insertion of genetic material from another source organism or progeny thereof that retain the inserted genetic material. The source organism may be of a different type of organism (e.g., a GMO plant may contain bacterial genetic material) or from the same type of organism (e.g., a GMO plant may contain genetic material from another plant). As used herein, recombinant and GMO are considered synonyms and indicate the presence of genetic material from a different source whereas mutagenized indicates altered genetic material from a corresponding wild- type organism but no genetic material from another source organism.

[0105] “Greater than additive,” refers to a phenomenon where the combined effect oftwo or more components (e.g., substances, materials, or processes) is greater than the sum of said components’ individual effects. Analogously, the expression “greater than additive weight ratio” refers to the ratio of the weight (or %wt) of component (A) (the herbicide enhancer composition) over the weight (or %wt) of component (B) (the one or more herbicides) in the herbicidal combination composition that when applied to a plant or locus thereof, results in a greater than additive herbicidal effect when compared to the herbicidal effect of each component. The greater than additive effect may be determined using any synergism or greater than additive calculation or by using the Colby Formula described herein. 22 59768580.3Attorney Docket No.278925-561797

[0106] “Herbicide” refers to a compound that controls or modifies the growth ofplants. The term “herbicidally effective amount” means the quantity of such a compound or combination of such compounds that is capable of producing a controlling or modifying effect on the growth of plants. Controlling or modifying effects include all deviation from natural development, for example killing, retardation, leaf burn, albinism, dwarfing and the like.

[0107] “Herbicide activity” means that upon or after exposing the unwanted to acompound or combination of compounds of the present disclosure, the target plant or unwanted plant undergoes controlled or modified effects that include all deviation from natural development, for example killing, retardation, leaf burn, albinism, dwarfing and the like, that result in the target plant or unwanted plant either dying, stopping, or slowing its growth; stopping or slowing its metabolism; stopping or slowing its reproduction; and / or precludes the target plant or unwanted plant from reproducing sexually, asexually, or any combination of the foregoing.

[0108] “Herbicide enhancer” or “herbicide enhancer composition” or “herbicidecomposition” refers to a compound or combination of compounds that, when combined with or added to an herbicide to control or modify the growth of plants, enhances the efficacy of the herbicide in controlling or modifying the growth of plants. In some embodiments, an herbicide composition can refer to an herbicide enhancer composition. In other embodiments, an herbicide composition can refer to a combination of: (A) an herbicide enhancer composition and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof.

[0109] “Herbicidally effective amount” refers to an amount of an active ingredientthat causes a “herbicidal effect,” i.e., an adversely modifying effect and includes deviations from natural development, killing, regulation, desiccation, retardation.

[0110] “Inhibiting” or “inhibit” or “combating” or “combat” or “controlling” or“control” or “killing” or any variation of these terms, refers to making something (e.g., the number of weeds, the functions and / or activities of the weeds, and / or the deleterious effect of the weed on a plant or to an area) less in size, amount, intensity, or degree. For example, in some embodiments, the application of an herbicidally effective amount of an herbicide enhancer composition or an herbicide combination composition of the present disclosure, to: (i) the weed, a locus of the weed, or habitat of the weed; (ii) a crop plant, a seed, a plant part, a locus of a crop plant, or an environment of a crop plant that is deleteriously affected by the weed; (iii) or a combination thereof, results in the following effect: a decrease in the number 23 59768580.3Attorney Docket No.278925-561797 of weeds, or inhibition of the weed’s activities, e.g., the weed dies stops or slows its movement; stops or slows its growth; fails to mature or flower if applicable; interferes with reproduction; and / or weakens, destroys, or otherwise disrupts the weed—relative to the number of weeds or the level of the weed’s activities that have not been exposed to an herbicidally effective amount of an herbicide enhancer composition or an herbicide combination composition of the present disclosure.

[0111] In some embodiments, combating, controlling, or inhibiting a weed, includesany measurable decrease, including up to complete inhibition, that achieves a desired result. For example, there may be a decrease of about 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 99%, or more, in the number of weeds or the activities thereof, that occurs when said weeds are treated with the herbicidally effective amount of the herbicide enhancer compositions or herbicide combination compositions of the present disclosure, compared to untreated weeds. About as used herein means within ± 10%, preferably ± 5% of a given value.

[0112] Thus, in some embodiments, the terms “combating, controlling, or inhibiting aweed,” refers to a decrease in the number of weeds, or an inhibition of the activities of the weeds (e.g., growth; reproduction; ability to flower, produce seeds, and / or produce viable seeds), that have received an herbicidally effective amount of the herbicide enhancer compositions or herbicide combination compositions of the present disclosure, that is at least about 0.1%, at least about 0.2%, at least about 0.3%, at least about 0.4%, at least about 0.5%, at least about 0.6%, at least about 0.7%, at least about 0.8%, at least about 0.9%, at least about 1%, at least about 1.25%, at least about 1.5%, at least about 1.75%, at least about 2%, at least about 2.25%, at least about 2.5%, at least about 2.75%, at least about 3%, at least about 3.25%, at least about 3.5%, at least about 3.75%, at least about 4%, at least about 4.25%, at least about 4.5%, at least about 4.75%, at least about 5%, at least about 5.25%, at least about 5.5%, at least about 5.75%, at least about 6%, at least about 6.25%, at least about 6.5%, at least about 6.75%, at least about 7%, at least about 7.25%, at least about 7.5%, at least about 7.75%, at least about 8%, at least about 8.25%, at least about 8.5%, at least about 8.75%, at least about 9%, at least about 9.25%, at least about 9.5%, at least about 9.75%, at least about 10%, at least about 11%, at least about 12%, at least about 13%, at least about 14%, at least about 15%, at least about 16%, at least about 17%, at least about 18%, at least about 19%, at least about 20%, at least about 21%, at least about 22%, at least about 23%, at least about 24%, at least about 25%, at least about 26%, at least about 27%, at least about 24 59768580.3Attorney Docket No.278925-561797 28%, at least about 29%, at least about 30%, at least about 31%, at least about 32%, at least about 33%, at least about 34%, at least about 35%, at least about 36%, at least about 37%, at least about 38%, at least about 39%, at least about 40%, at least about 41%, at least about 42%, at least about 43%, at least about 44%, at least about 45%, at least about 46%, at least about 47%, at least about 48%, at least about 49%, at least about 50%,at least about 50%, at least about 51%, at least about 52%, at least about 53%, at least about 54%, at least about 55%, at least about 56%, at least about 57%, at least about 58%, at least about 59%, at least about 60%, at least about 61%, at least about 62%, at least about 63%, at least about 64%, at least about 65%, at least about 66%, at least about 67%, at least about 68%, at least about 69%, at least about 70%, at least about 71%, at least about 72%, at least about 73%, at least about 74%, at least about 75%, at least about 80%, at least about 85%, at least about 90%, at least about 95%, at least about 100%, or a greater than a 100%, relative to the number of weeds, or the inhibition of the activities of the weeds (e.g., growth; reproduction; ability to flower, produce seeds, and / or produce viable seeds), that have not received the herbicidally effective amount of the herbicide enhancer compositions or herbicide combination compositions of the present disclosure.

[0113] Inhibiting, combatting, controlling, or killing a weed can be measured by anyof the various methods known in the art. For example, killing a weed can be determined as a percentage as compared to untreated plants following a standard procedure wherein plant mortality and growth reduction is visually assessed by one skilled in the art. Control may be defined, for instance, in terms of mean plant weight reduction or percentage of plants that fail to emerge following preemergence herbicide application.

[0114] “Insensitive” or “insensitivity” refers to the ability to be wholly or partiallyunaffected by the presence or application of one of more herbicide(s), for example to resist the toxic effects of an herbicide when applied. “Insensitivity” indicates a plant or portion thereof is capable of growing in the presence of an amount of herbicide that normally causes growth inhibition, and / or plant death in a “sensitive” (e.g., a wild-type) plant or portion thereof. Accordingly, a plant, for example, a weed or crop, is “insensitive” if it has the inherited ability (either via mutation, selective breeding or induced through genetically recombinant / engineering techniques) to survive and reproduce following exposure to a dose of herbicide that would normally be lethal and / or inhibit growth and reproduction to the wild- type plant. In some embodiments, a trait conferring insensitivity to one or more herbicides means that the presence of the trait can confer improved tolerance to an herbicide upon a cell, plant, or seed as compared to the wild-type or control cell, plant, or seed. Crops comprising a 25 59768580.3Attorney Docket No.278925-561797 trait introduced genetically by recombinant means or by selection, conferring insensitivity to one or more herbicides can continue to grow and are minimally affected by the presence of the one or more herbicides. In some embodiments, there may be complete or partial insensitivity to a particular herbicide, and may be expressed as a percent (%) insensitivity to a particular herbicide.

[0115] In some embodiments, “insensitivity” refers to plants in which higher doses ofan herbicide are required to produce undesirable effects similar to those seen in non-tolerant plants (e.g., pronounced leaf cupping, stunting, and death). An insensitive plant need not possess absolute or complete insensitivity such that no detrimental effect to the plant or plant variety is observed when herbicide is applied. Instead, an insensitive plant may simply be less affected by herbicide than a comparable sensitive (i.e., non-tolerant) plant or variety. In some embodiments, a plant may be naturally insensitive to the herbicide or may be genetically enhanced to be insensitive the herbicide. Insensitivity to a specific herbicide can be conferred, for example, by engineering genes into crops that encode appropriate herbicide metabolizing enzymes and / or insensitive herbicide targets.

[0116] Overcoming insensitivity to a particular herbicide or collection of two or moreherbicides means that the herbicidal combination compositions of the present invention decreases the sensitivity of a plant (herbicide resistant monocot or dicot plant) to a herbicide at the same concentration of the herbicide present in the herbicidal combination composition which is the concentration of herbicide that the plant is insensitive to in the absence of the herbicidal combination composition. For example, in a purely hypothetical illustration, a weed that is resistant to glufosinate when the plant is treated with a 0.01% wt% solution of glufosinate will have its insensitivity decreased when treated with a herbicidal combination composition of the present disclosure containing the same concentration of glufosinate, i.e. 0.01% wt%. The decrease in insensitivity will result in the herbicide resistant plant being sensitive to the herbicide present in the herbicidal combination composition.

[0117] “Iodide salt” refers to a compound that contains iodine in anionic form asiodide (I-), ionically bound or paired to a metal or positively charged ion (cation) to form a salt. Nonlimiting examples of iodide salts are KI, NaI, or NH4I.

[0118] “Lactoperoxidase” (LP) refers to an enzyme that catalyzes the reduction ofperoxides such as hydrogen peroxide (H2O2). It is a free radical-producing (FRP) enzyme. A nonlimiting example of a source of lactoperoxidase is bovine milk. 26 59768580.3Attorney Docket No.278925-561797

[0119] “Locus” as used herein means fields in or on which plants are growing, orwhere seeds of cultivated plants are sown, or where seed will be placed into the soil. It includes soil, seeds, and seedlings, as well as established vegetation.

[0120] “Over the top” refers to applying or administering a composition such as acompound, herbicide, herbicide enhancer, or combination thereof over the top of a plant such as a crop or target plant, resulting in the direct application of said composition onto the above-ground parts of a plant.

[0121] “pH buffer” refers to a solution containing a compound or mixture ofcompounds that helps to maintain the pH of a solution within a desired narrow, stable range when acids or bases are added. Nonlimiting examples of pH buffers, include a phosphate buffer, an acetate buffer, a citrate buffer, a borate buffer, a Tris buffer, a MOPS buffer, a HEPES buffer, a MES buffer, a PIPES buffer, an ammonia / ammonium buffer, a carbonate buffer, a carboxylic acid buffer, an amine-based buffer, or an amino acid-based buffer.

[0122] “Plants” refers to all physical parts of a plant, including seeds, seedlings,saplings, roots, tubers, stems, stalks, foliage, and fruits. It includes whole plants, plant tissues, plant cells, plant parts, plant organs (e.g., leaves, stems, roots, etc.), seeds, propagules, embryos and progeny of the same. Plant cells can be differentiated or undifferentiated (e.g. callus, suspension culture cells, protoplasts, leaf cells, root cells, phloem cells, and pollen).

[0123] “Plant field” refers to an area or environment where plants are cultivated orgrown.

[0124] “Plant propagation material” denotes all generative parts of a plant, forexample seeds or vegetative parts of plants such as cuttings and tubers. It includes seeds in the strict sense, as well as roots, fruits, tubers, bulbs, rhizomes, and parts of plants.

[0125] “Ratio” refers to the quantitative relation between two amounts showing thenumber of times one value contains or is contained within the other.

[0126] “Right-of-way” or “ROW” refers to land designation that grants individuals orentities the right to pass through and / or utilize a strip of land for a specific purpose. In land management contexts, a ROW may refer to the corridors where utility lines, railways, highways, pipelines, or other infrastructure is installed. ROWs to ensure safe and reliable service by preventing vegetation overgrowth, minimizing fire hazards, and protecting equipment access. Non-limiting examples of ROWs include: a residential land area; a commercial land area; a forest; a highway; a road; beside a road; beside a utility structure; an airport; a railroad; a railroad track; an area around an electric utility; a pipeline; a public surface drainage way; an irrigation waterway; a bank of a public barge way; an area around a 27 59768580.3Attorney Docket No.278925-561797 lock; an area around a dam; a bicycle trail; a bridle trail; a public path; a public trail; or an area outside an established recreational area.

[0127] “Shortly before application” means preferably less than 6 hours, morepreferably less than 3 hours, and even more preferably less than 1 hour before application of a composition herein onto, for example, an unwanted plant and / or their habitat.

[0128] “Thiocyanate salt” refers to a compound that contains the anionic thiocyanateion (SCN-), ionically bound or paired to a metal or positively charged ion (cation) to form a salt. Nonlimiting examples of thiocyanate salts are KSCN, NaSCN, or NH4SCN.

[0129] “Unwanted plant growth” refers to the presence and / or growth of any plantthat is undesired in a specific area, either based on the nature of the plant itself or because of the location or area in which it is present and / or growing. This encompasses all types of plants that are not the intended, cultivated, or desired species of plant in a particular plant environment or setting.

[0130] “Weed” refers to a plant that is not desirable in a particular area. Conversely, a“crop plant” refers to a plant which is desired in a particular area. Thus, in some embodiments, a weed is a non-crop plant or a non-crop species, whereas in other embodiments, a weed can be a crop species which is sought to be eliminated from a particular area.

[0131] “2,4-D choline” refers to a derivative of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), in which 2,4-D is bound to the compound choline.

[0132] HERBICIDE ENHANCER COMPOSITIONS

[0133] The present disclosure contemplates compositions, i.e., herbicide enhancercompositions, for enhancing activity of diverse chemistries with herbicidal activity. In some embodiments, the herbicide enhancer compositions are referred to herein as: “EX”, “Enhancer” and “enhancer compositions” and are used interchangeably herein. The present disclosure provides new management tools for farms, utilities, roadside management, forest management, or anywhere that plant growth is controlled by herbicides, defoliants, or desiccants. In some embodiments, the herbicide enhancer compositions provide efficient and economical farm operations typically associated with harvesting or no-till planting and will reduce the use of active ingredients in commercial products. In some embodiments, the herbicide enhancer compositions provide improved crop yields and reduced environmental impacts. In some embodiments, the herbicide enhancer compositions decrease the likelihood of resistance development in diverse plant species while simultaneously providing an alternative, effective method for managing harvest operations and planting in major crop 28 59768580.3Attorney Docket No.278925-561797 production systems. In some embodiments, the herbicide enhancer compositions reduce agrochemical dosage rates of herbicides. The compositions are dormant and become active upon exposure to hydration, oxygen, or mixing.

[0134] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises an enzyme-activated, non-selective enhancer of an herbicide, crop desiccant, or defoliant (enzyme-activated herbicide). In some embodiments, the enzyme- activated herbicide formulations and methods described herein are optimized for eliminating undesirable plants and plant tissue.

[0135] In some embodiments, an herbicide enhancer composition may be dormant,and become active upon exposure to hydration, oxygen, or mixing.

[0136] In some embodiments, an herbicide enhancer composition comprises an iodidesalt and a thiocyanate salt.

[0137] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is KI, NaI, NH4I, or combinations thereof.

[0138] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is KI.

[0139] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is NaI.

[0140] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is NH4I.

[0141] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is KI, NaI, NH4I, or combinations thereof, and wherein said iodide salt has a concentration ranging from about 0.1 mM to about 40 mM.

[0142] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said iodide salt is KI, NaI, NH4I, or combinations thereof, and wherein said iodide salt has a concentration of about 0.1 mM, about 0.2 mM, about 0.3 mM, about 0.4 mM, about 0.5 mM, about 0.6 mM, about 0.7 mM, about 0.8 mM, about 0.9 mM, about 1.0 mM, about 1.1 mM, about 1.2 mM, about 1.3 mM, about 1.4 mM, about 1.5 mM, about 1.6 mM, about 1.7 mM, about 1.8 mM, about 1.9 mM, about 2.0 mM, about 2.1 mM, about 2.2 mM, about 2.3 mM, about 2.4 mM, about 2.5 mM, about 2.6 mM, about 2.7 mM, about 2.8 mM, about 2.9 mM, about 3.0 mM, about 3.1 mM, about 3.2 mM, about 3.3 mM, about 3.4 mM, about 3.5 mM, about 3.6 mM, about 3.7 mM, about 3.8 mM, 29 59768580.3Attorney Docket No.278925-561797 about 3.9 mM, about 4.0 mM, about 4.1 mM, about 4.2 mM, about 4.3 mM, about 4.4 mM, about 4.5 mM, about 4.6 mM, about 4.7 mM, about 4.8 mM, about 4.9 mM, about 5.0 mM, about 5.1 mM, about 5.2 mM, about 5.3 mM, about 5.4 mM, about 5.5 mM, about 5.6 mM, about 5.7 mM, about 5.8 mM, about 5.9 mM, about 6.0 mM, about 6.1 mM, about 6.2 mM, about 6.3 mM, about 6.4 mM, about 6.5 mM, about 6.6 mM, about 6.7 mM, about 6.8 mM, about 6.9 mM, about 7.0 mM, about 7.1 mM, about 7.2 mM, about 7.3 mM, about 7.4 mM, about 7.5 mM, about 7.6 mM, about 7.7 mM, about 7.8 mM, about 7.9 mM, about 8.0 mM, about 8.1 mM, about 8.2 mM, about 8.3 mM, about 8.4 mM, about 8.5 mM, about 8.6 mM, about 8.7 mM, about 8.8 mM, about 8.9 mM, about 9.0 mM, about 9.1 mM, about 9.2 mM, about 9.3 mM, about 9.4 mM, about 9.5 mM, about 9.6 mM, about 9.7 mM, about 9.8 mM, about 9.9 mM, or about 10 mM.

[0143] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, NH4SCN, or combinations thereof.

[0144] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is KSCN.

[0145] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is NaSCN.

[0146] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is NH4SCN.

[0147] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, NH4SCN, or combinations thereof, and wherein said thiocyanate salt has a concentration ranging from between about 1 mM to about 80 mM.

[0148] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, NH4SCN, or combinations thereof, and wherein said thiocyanate salt has a concentration ranging from between: about 1 mM to about 80 mM, about 5 mM to about 40 mM, 10 mM to about 40 mM, about 10 mM to about 60 mM, about 20 mM to about 40 mM, about 40 mM to about 80 mM, or between about 20 mM and about 80 mM, and all numerical values therebetween.

[0149] In some embodiments, the herbicide enhancer composition comprises aniodide salt and a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, NH4SCN, or combinations thereof, and wherein said thiocyanate salt has a concentration of about 1 mM, about 5 mM, about 10 mM, about 11 mM, about 12 mM, about 13 mM, about 14 mM, 30 59768580.3Attorney Docket No.278925-561797 about 15 mM, about 16 mM, about 17 mM, about 18 mM, about 19 mM, about 20 mM, about 21 mM, about 22 mM, about 23 mM, about 24 mM, about 25 mM, about 26 mM, about 27 mM, about 28 mM, about 29 mM, about 30 mM, about 31 mM, about 32 mM, about 33 mM, about 34 mM, about 35 mM, about 36 mM, about 37 mM, about 38 mM, about 39 mM, about 40 mM, about 41 mM, about 42 mM, about 43 mM, about 44 mM, about 45 mM, about 46 mM, about 47 mM, about 48 mM, about 49 mM, about 50 mM, about 51 mM, about 52 mM, about 53 mM, about 54 mM, about 55 mM, about 56 mM, about 57 mM, about 58 mM, about 59 mM, about 60 mM, about 61 mM, about 62 mM, about 63 mM, about 64 mM, about 65 mM, about 66 mM, about 67 mM, about 68 mM, about 69 mM, about 70 mM, about 71 mM, about 72 mM, about 73 mM, about 74 mM, about 75 mM, about 76 mM, about 77 mM, about 78 mM, about 79 mM, or about 80 mM.

[0150] In some embodiments, an herbicide enhancer composition of the presentdisclosure further a pH buffer.

[0151] In some embodiments, an herbicide enhancer composition of the presentdisclosure can further comprise a pH buffer, wherein said pH buffer is a phosphate buffer, an acetate buffer, a citrate buffer, a borate buffer, a Tris buffer, a MOPS buffer, a HEPES buffer, a MES buffer, a PIPES buffer, an ammonia / ammonium buffer, a carbonate buffer, a carboxylic acid buffer, an amine-based buffer, or an amino acid-based buffer.

[0152] In some embodiments, an herbicide enhancer composition of the presentdisclosure further comprises a pH buffer, wherein said pH buffer has a phosphate salt concentration ranging between about 1 mM to about 50 mM.

[0153] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a pH buffer, wherein said pH buffer has a phosphate salt concentration of about 1 mM, about 2 mM, about 3 mM, about 4 mM, about 5 mM, about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mM, about 11 mM, about 12 mM, about 13 mM, about 14 mM, about 15 mM, about 16 mM, about 17 mM, about 18 mM, about 19 mM, about 20 mM, about 21 mM, about 22 mM, about 23 mM, about 24 mM, about 25 mM, about 26 mM, about 27 mM, about 28 mM, about 29 mM, about 30 mM, about 31 mM, about 32 mM, about 33 mM, about 34 mM, about 35 mM, about 36 mM, about 37 mM, about 38 mM, about 39 mM, about 40 mM, about 41 mM, about 42 mM, about 43 mM, about 44 mM, about 45 mM, about 46 mM, about 47 mM, about 48 mM, about 49 mM, or about 50 mM.

[0154] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a pH buffer, wherein said pH buffer comprises NaH2PO4. 31 59768580.3Attorney Docket No.278925-561797

[0155] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a monosaccharide.

[0156] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a sugar. In some embodiments, the sugar can be a monosaccharide, wherein said monosaccharide is glucose or fructose.

[0157] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a monosaccharide, wherein said monosaccharide is glucose or fructose, and wherein said monosaccharide has a concentration ranging from about 1 mM to about 200 mM, from about 1 mM to about 10 mM, or from about 5 mM to about 50 mM.

[0158] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a monosaccharide, wherein said monosaccharide is glucose or fructose, and wherein said monosaccharide has a concentration of about 1 mM, about 2 mM, about 3 mM, about 4 mM, about 5 mM, about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mM, about 11 mM, about 12 mM, about 13 mM, about 14 mM, about 15 mM, about 16 mM, about 17 mM, about 18 mM, about 19 mM, about 20 mM, about 21 mM, about 22 mM, about 23 mM, about 24 mM, about 25 mM, about 26 mM, about 27 mM, about 28 mM, about 29 mM, about 30 mM, about 31 mM, about 32 mM, about 33 mM, about 34 mM, about 35 mM, about 36 mM, about 37 mM, about 38 mM, about 39 mM, about 40 mM, about 41 mM, about 42 mM, about 43 mM, about 44 mM, about 45 mM, about 46 mM, about 47 mM, about 48 mM, about 49 mM, about 50 mM, about 51 mM, about 52 mM, about 53 mM, about 54 mM, about 55 mM, about 56 mM, about 57 mM, about 58 mM, about 59 mM, about 60 mM, about 61 mM, about 62 mM, about 63 mM, about 64 mM, about 65 mM, about 66 mM, about 67 mM, about 68 mM, about 69 mM, about 70 mM, about 71 mM, about 72 mM, about 73 mM, about 74 mM, about 75 mM, about 76 mM, about 77 mM, about 78 mM, about 79 mM, about 80 mM, about 81 mM, about 82 mM, about 83 mM, about 84 mM, about 85 mM, about 86 mM, about 87 mM, about 88 mM, about 89 mM, about 90 mM, about 91 mM, about 92 mM, about 93 mM, about 94 mM, about 95 mM, about 96 mM, about 97 mM, about 98 mM, about 99 mM, about 100 mM, about 101 mM, about 102 mM, about 103 mM, about 104 mM, about 105 mM, about 106 mM, about 107 mM, about 108 mM, about 109 mM, about 110 mM, about 111 mM, about 112 mM, about 113 mM, about 114 mM, about 115 mM, about 116 mM, about 117 mM, about 118 mM, about 119 mM, about 120 mM, about 121 mM, about 122 mM, about 123 mM, about 124 mM, about 125 mM, about 126 mM, about 127 mM, about 128 mM, about 129 mM, about 130 mM, about 131 mM, about 132 mM, about 133 mM, about 134 mM, about 135 mM, about 136 mM, about 137 mM, about 138 mM, 32 59768580.3Attorney Docket No.278925-561797 about 139 mM, about 140 mM, about 141 mM, about 142 mM, about 143 mM, about 144 mM, about 145 mM, about 146 mM, about 147 mM, about 148 mM, about 149 mM, about 150 mM, about 151 mM, about 152 mM, about 153 mM, about 154 mM, about 155 mM, about 156 mM, about 157 mM, about 158 mM, about 159 mM, about 160 mM, about 161 mM, about 162 mM, about 163 mM, about 164 mM, about 165 mM, about 166 mM, about 167 mM, about 168 mM, about 169 mM, about 170 mM, about 171 mM, about 172 mM, about 173 mM, about 174 mM, about 175 mM, about 176 mM, about 177 mM, about 178 mM, about 179 mM, about 180 mM, about 181 mM, about 182 mM, about 183 mM, about 184 mM, about 185 mM, about 186 mM, about 187 mM, about 188 mM, about 189 mM, about 190 mM, about 191 mM, about 192 mM, about 193 mM, about 194 mM, about 195 mM, about 196 mM, about 197 mM, about 198 mM, about 199 mM, or about 200 mM.

[0159] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises an enzyme capable of producing hydrogen peroxide. For example, in some embodiments, an herbicide enhancer composition of the present disclosure comprises an enzyme capable of catalyzing the oxidation of glucose to produce hydrogen peroxide and gluconic acid. In other embodiments, an herbicide enhancer composition of the present disclosure comprises an enzyme capable of catalyzing the oxidation of thiocyanate (SCN⁻) ions in the presence of hydrogen peroxide (H₂O₂), wherein the enzyme produces one or more reactive compounds, e.g., oxidized thiocyanate (OSCN⁻), hypothiocyanite (OSCN⁻), and / or hydroxyl radicals.

[0160] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a hydrogen peroxide producing enzyme.

[0161] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a hydrogen peroxide producing enzyme, wherein the hydrogen peroxide producing enzyme is at a concentration of about 0.1 U / mL to about 50 U / mL, about 1 U / mL to about 10 U / mL, about 10 U / mL to about 20 U / mL, about 20 U / mL to about 30 U / mL, about 30 U / mL to about 40 U / mL, or about 40 U / mL to about 50 U / mL.

[0162] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a hydrogen peroxide producing enzyme, wherein the hydrogen peroxide producing enzyme is at a concentration of about 0.1 U / mL, about 1 U / mL, about 2 U / mL, about 3 U / mL, about 4 U / mL, about 5 U / mL, about 6 U / mL, about 7 U / mL, about 8 U / mL, about 9 U / mL, about 10 U / mL, about 11 U / mL, 33 59768580.3Attorney Docket No.278925-561797 about 12 U / mL, about 13 U / mL, about 14 U / mL, about 15 U / mL, about 16 U / mL, about 17 U / mL, about 18 U / mL, about 19 U / mL, about 20 U / mL, about 21 U / mL, about 22 U / mL, about 23 U / mL, about 24 U / mL, about 25 U / mL, about 26 U / mL, about 27 U / mL, about 28 U / mL, about 29 U / mL, about 30 U / mL, about 31 U / mL, about 32 U / mL, about 33 U / mL, about 34 U / mL, about 35 U / mL, about 36 U / mL, about 37 U / mL, about 38 U / mL, about 39 U / mL, about 40 U / mL, about 41 U / mL, about 42 U / mL, about 43 U / mL, about 44 U / mL, about 45 U / mL, about 46 U / mL, about 47 U / mL, about 48 U / mL, about 49 U / mL, or about 50 U / mL.

[0163] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a hydrogen peroxide producing enzyme, wherein the hydrogen peroxide producing enzyme is an oxidase, e.g., a glucose oxidase.

[0164] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises an oxidase, for example, a glucose oxidase.

[0165] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises glucose oxidase, wherein said glucose oxidase is at a concentration of about 0.1 U / mL to about 50 U / mL, about 1 U / mL to about 10 U / mL, about 10 U / mL to about 20 U / mL, about 20 U / mL to about 30 U / mL, about 30 U / mL to about 40 U / mL, or about 40 U / mL to about 50 U / mL.

[0166] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises glucose oxidase, wherein said glucose oxidase is at a concentration of about 0.1 U / mL, about 1 U / mL, about 2 U / mL, about 3 U / mL, about 4 U / mL, about 5 U / mL, about 6 U / mL, about 7 U / mL, about 8 U / mL, about 9 U / mL, about 10 U / mL, about 11 U / mL, about 12 U / mL, about 13 U / mL, about 14 U / mL, about 15 U / mL, about 16 U / mL, about 17 U / mL, about 18 U / mL, about 19 U / mL, about 20 U / mL, about 21 U / mL, about 22 U / mL, about 23 U / mL, about 24 U / mL, about 25 U / mL, about 26 U / mL, about 27 U / mL, about 28 U / mL, about 29 U / mL, about 30 U / mL, about 31 U / mL, about 32 U / mL, about 33 U / mL, about 34 U / mL, about 35 U / mL, about 36 U / mL, about 37 U / mL, about 38 U / mL, about 39 U / mL, about 40 U / mL, about 41 U / mL, about 42 U / mL, about 43 U / mL, about 44 U / mL, about 45 U / mL, about 46 U / mL, about 47 U / mL, about 48 U / mL, about 49 U / mL, or about 50 U / mL.

[0167] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises a peroxidase, for example, a hydrogen peroxide (H2O2). 34 59768580.3Attorney Docket No.278925-561797

[0168] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises hydrogen peroxide (H2O2), wherein said H2O2is at a concentration ranging from about 0.001 mM to about 50 mM.

[0169] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises hydrogen peroxide (H2O2), wherein said H2O2 is at a concentration of about 0.001mM, about 0.005 mM, about 0.01 mM, about 0.05 mM, about 0.1 mM, about 0.5 mM, about 1 mM, about 2 mM, about 3 mM, about 4 mM, about 5 mM, about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mM, about 11 mM, about 12 mM, about 13 mM, about 14 mM, about 15 mM, about 16 mM, about 17 mM, about 18 mM, about 19 mM, about 20 mM, about 21 mM, about 22 mM, about 23 mM, about 24 mM, about 25 mM, about 26 mM, about 27 mM, about 28 mM, about 29 mM, about 30 mM, about 31 mM, about 32 mM, about 33 mM, about 34 mM, about 35 mM, about 36 mM, about 37 mM, about 38 mM, about 39 mM, about 40 mM, about 41 mM, about 42 mM, about 43 mM, about 44 mM, about 45 mM, about 46 mM, about 47 mM, about 48 mM, about 49 mM, or about 50 mM.

[0170] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a free radical producing (FRP) enzyme operable to catalyze hydrogen peroxide, iodide, and thiocyanate.

[0171] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a free radical producing (FRP) enzyme operable to catalyze hydrogen peroxide, iodide, and thiocyanate, wherein said FRP is at a concentration ranging from about 0.3 U / mL to about 3 U / mL, about 1 U / mL to about 5 U / mL, about 5 U / mL to about 10 U / mL, about 10 U / mL to about 15 U / mL, about 15 U / mL to about 20 U / mL, about 20 U / mL to about 25 U / mL, or about 12 U / mL to about 25 U / mL.

[0172] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a free radical producing (FRP) enzyme operable to catalyze hydrogen peroxide, iodide, and thiocyanate, wherein said FRP is at a concentration of about 0.5 U / mL, about 1 U / mL, about 2 U / mL, about 3 U / mL, about 4 U / mL, about 5 U / mL, about 6 U / mL, about 7 U / mL, about 8 U / mL, about 9 U / mL, about 10 U / mL, about 11 U / mL, about 12 U / mL, about 13 U / mL, about 14 U / mL, about 15 U / mL, about 16 U / mL, about 17 U / mL, about 18 U / mL, about 19 U / mL, about 20 U / mL, about 21 U / mL, about 22 U / mL, about 23 U / mL, about 24 U / mL, about 25 U / mL, about 26 U / mL, about 27 U / mL, about 28 U / mL, about 29 U / mL, about 30 U / mL, about 31 U / mL, about 32 U / mL, about 33 U / mL, about 34 U / mL, about 35 U / mL, about 36 U / mL, about 37 35 59768580.3Attorney Docket No.278925-561797 U / mL, about 38 U / mL, about 39 U / mL, about 40 U / mL, about 41 U / mL, about 42 U / mL, about 43 U / mL, about 44 U / mL, about 45 U / mL, about 46 U / mL, about 47 U / mL, about 48 U / mL, about 49 U / mL, or about 50 U / mL.

[0173] In some embodiments, an herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a pH buffer, a sugar, and further comprises a free radical producing (FRP) enzyme operable to catalyze hydrogen peroxide, iodide, and thiocyanate, wherein the free radical producing (FRP) enzyme is a peroxidase.

[0174] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises lactoperoxidase.

[0175] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises lactoperoxidase, wherein said lactoperoxidase is at a concentration ranging from about 0.5 U / mL to about 50 U / mL.

[0176] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises lactoperoxidase, wherein said lactoperoxidase is at a concentration ranging from about 0.3 U / mL to about 3 U / mL, about 1 U / mL to about 5 U / mL, about 5 U / mL to about 10 U / mL, about 10 U / mL to about 15 U / mL, about 15 U / mL to about 20 U / mL, about 20 U / mL to about 25 U / mL, or about 12 U / mL to about 25 U / mL.

[0177] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprises lactoperoxidase, wherein said lactoperoxidase is at a concentration of about 0.5 U / mL, about 1 U / mL, about 2 U / mL, about 3 U / mL, about 4 U / mL, about 5 U / mL, about 6 U / mL, about 7 U / mL, about 8 U / mL, about 9 U / mL, about 10 U / mL, about 11 U / mL, about 12 U / mL, about 13 U / mL, about 14 U / mL, about 15 U / mL, about 16 U / mL, about 17 U / mL, about 18 U / mL, about 19 U / mL, about 20 U / mL, about 21 U / mL, about 22 U / mL, about 23 U / mL, about 24 U / mL, about 25 U / mL, about 26 U / mL, about 27 U / mL, about 28 U / mL, about 29 U / mL, about 30 U / mL, about 31 U / mL, about 32 U / mL, about 33 U / mL, about 34 U / mL, about 35 U / mL, about 36 U / mL, about 37 U / mL, about 38 U / mL, about 39 U / mL, about 40 U / mL, about 41 U / mL, about 42 U / mL, about 43 U / mL, about 44 U / mL, about 45 U / mL, about 46 U / mL, about 47 U / mL, about 48 U / mL, about 49 U / mL, or about 50 U / mL.

[0178] In some embodiments, an herbicide enhancer composition of the presentdisclosure has a pH of about 4.0, about 5.0, about 6.0, about 7.0, about 8.0, about 5.0 to about 8.0, or about 6.0 to about 7.0, and all values inclusive of, and between pH of about 4.0 and about 8.0. 36 59768580.3Attorney Docket No.278925-561797

[0179] In some embodiments, an herbicide enhancer composition of the presentdisclosure comprising KI and / or KSCN is further activated by the addition of an enzyme system that works with a greater than additive effect with existing commercial herbicides. The enhancer comprises iodo- and / or hypo- and inter- pseudo-halogen species that are oxidative products biocatalytically generated from thiocyanate and iodide by glucose oxidase (GOx). In some embodiments, the GOx is combined with lactoperoxidase (LP). GOx generates hydrogen peroxide (H2O2) from D-glucose and oxygen, while LP catalyzes the oxidation of thiocyanate and iodide ions with H2O2to transiently produce hypothiocyanite (OSCN-) and hypoiodite (OI-). These are subsequently converted to a mixture of oxidative species including iodine (I2), triiodide (I3-) and interspecies such as I2SCN- and I(SCN)2-. In some embodiments, the compositions are dormant and become active upon exposure to hydration, oxygen, or mixing.

[0180] One unit of glucose oxidase will oxidize 1.0 µMole of β-D-glucose to D-gluconic acid and hydrogen peroxide per minute at pH 5.1 and at 35ºC. One unit of lactoperoxidase oxidizes 1 mMol ABTS per minute under standard assay conditions.

[0181] The benefits of the herbicide enhancers of the disclosure include, but are notlimited to, compatibility with conventional herbicides, compatibility with organic herbicides, compatibility with existing chemical herbicides, reduced current herbicide use rates of up to 90%, mitigation of weed resistance, and / or use with formulated products. The EX herbicide enhancers can be formulated as liquids, solids, granulated forms, or powdered forms.

[0182] The disclosure provides herbicide enhancer compositions (EX) that have, insome embodiments, iodine and thiocyanate formulations. In other embodiments, the EX formulations are further activated by the addition of enzymes or enzyme systems that work additively or greater than additively with a variety of existing herbicides as described herein. The broad-spectrum herbicide enhancers may comprise iodo-, hypo-, or inter- pseudo- halogen species that are oxidative products biocatalytically generated from thiocyanate and / or iodide. In some embodiments, they can be further activated by two natural enzymes, e.g., an oxidase, for example, glucose oxidase (GOx) and a peroxidase, for example, a lactoperoxidase (LP). GOx generates hydrogen peroxide (H2O2) from D-glucose and oxygen, while LP catalyzes the oxidation of thiocyanate and iodide ions with H2O2to transiently produce hypothiocyanite (OSCN-) and hypoiodite (OI-). These are subsequently converted to a mixture of oxidative species including iodine (I2), triiodide (I3-) and interspecies such as I2SCN- and I(SCN)2-. 37 59768580.3Attorney Docket No.278925-561797

[0183] In some embodiments, biocatalytically generated herbicides (ZX herbicides).The herbicides consist of iodo-, hypo-, or inter- pseudo-halogen species that are oxidative products biocatalytically generated from thiocyanate and iodide by glucose oxidase (GOx). In some embodiments, the GOx is combined with lactoperoxidase (LP). GOx generates hydrogen peroxide (H2O2) from D-glucose and oxygen, while LP catalyzes the oxidation of thiocyanate and iodide ions with H2O2to transiently produce hypothiocyanite (OSCN-) and hypoiodite (OI-). These are subsequently converted to a mixture of oxidative species including iodine (I2), triiodide (I3-) and interspecies such as I2SCN- and I(SCN)2-. In some embodiments, the compositions are dormant and become active upon exposure to hydration, oxygen, or mixing.

[0184] The lactoperoxidase / glucose oxidase (LP / GOx) system occurs naturally inbodily fluids such as milk, saliva, tears, and mucous (Bosch et al., J.Applied Microbiol., 89(2), 215–24 (2000)). This system utilizes thiocyanate (SCN-) and iodide (I-), two naturally occurring compounds that are harmless to mammals and higher organisms (Welk et al. Archives of Oral Biology, 2587 (2011)). LP catalyzes the oxidation of thiocyanate and iodide ions into hypothiocyanite (OSCN-) and hypoiodite (OI-), respectively, in the presence of hydrogen peroxide (H2O2). The H2O2in this system is provided by the activity of GOx on β- D-glucose in the presence of oxygen. These free radical compounds, in turn, oxidizesulfhydryl groups in the cell membranes (Purdy, Tenovuo et al. Infection and Immunity,39(3), 1187 (1983); Bosch et al., J.Applied Microbiol., 89(2), 215–24 (2000), leading to impairment of membrane permeability (Wan, Wang et al. Biochemistry Journal, 362, 355– 362 (2001)) and ultimately microbial cell death. Furthermore, the LP / GOx system functions in two phases: (1) the generation and action of hypothiocyanite and hypoiodite on cell membranes, and then, when these compounds are depleted, (2) excess H2O2 builds up, enacting its own oxidative damage on cellular structures (Reiter, Marshall et al.1976). The forgoing references are incorporated herein by reference in their entirety.

[0185] The enzyme system has been deployed and approved in the industry forbiofilm control such as toothpaste and milk anti-spoiling agents. The system is largely non- specific and robust with few reaction requirements. The effective pH range is 3-7 with a peak LP activity at pH 5 (Reiter, Marshall et al.1976; Purdy, Tenovuo et al.1983). Other than pH, the only strict requirement for activity of the LP / GOx system is the presence of oxygen, without which GOx can’t generate H2O2from glucose. 38 59768580.3Attorney Docket No.278925-561797

[0186] In embodiments where β-D-Glucose is oxidized to H2O2, or where cellulosederived sugars are oxidized to H2O2, cellulase enzymes may be provided with the compositions of the disclosure.

[0187] In some embodiments, the cellulases are exocellulases, endocellulases,hemicellulases, or combinations thereof known in the art. Endocellulase (EC 3.2.1.4) randomly cleaves internal bonds at amorphous sites that create new chain ends. Exocellulase (EC 3.2.1.91) cleaves two to four units from the ends of the exposed chains produced by endocellulase, resulting in the tetrasaccharides or disaccharides, such as cellobiose. There are two main types of exocellulases [or cellobiohydrolases (CBH)] - CBHI works processively from the reducing end, and CBHII works processively from the nonreducing end of cellulose. Cellobiase (EC 3.2.1.21) or beta-glucosidase hydrolyses the exocellulase product into individual monosaccharides. Oxidative cellulases depolymerize cellulose by radical reactions, as for instance cellobiose dehydrogenase (acceptor). Cellulose phosphorylases depolymerize cellulose using phosphates instead of water.

[0188] In other embodiments, endocellulases may include EC 3.2.1.4, endo-1,4- beta-D-glucanase, beta-1,4-glucanase, beta-1,4-endoglucan hydrolase, celluase A, cellulosin AP, endoglucanase D, alkali cellulase, cellulase A 3, celludextrinase, 9.5 cellulase, avicelase, pancellase SS, and 1,4-(1,3, 1,4)-beta-D-glucan 4-glucanohydrolase). Cellulases enzymes are typically produced by fungi, bacteria, and protozoans of cellulose). Other names for 'endoglucanases' are: endo-1,4-beta-glucanase, carboxymethyl cellulase (CMCase), endo-1,4- beta-D-glucanase, beta-1,4-glucanase, beta-1,4-endoglucan hydrolase, and celludextrinase.

[0189] In some embodiments, an herbicide enhancer composition comprises ahydrogen peroxide producing (HPP) enzymes. In certain embodiments, the HPP enzymes are oxidases that may be of the EX 1.1.3 subgenus. In particular embodiments, the oxidase may be EC 1.1.3.3 (malate oxidase), EC 1.1.3.4 (glucose oxidase), EC 1.1.3.5 (hexose oxidase), EC 1.1.3.6 (cholesterol oxidase), EC 1.1.3.7 (aryl-alcohol oxidase), EC 1.1.3.8 (L- gulonolactone oxidase), EC 1.1.3.9 (galactose oxidase), EC 1.1.3.10 (pyranose oxidase), EC 1.1.3.11 (L-sorbose oxidase), EC 1.1.3.12 (pyridoxine 4-oxidase), EC 1.1.3.13 (alcohol oxidase), EC 1.1.3.14 (catechol oxidase), EC 1.1.3.15 (2-hydroxy acid oxidase), EC 1.1.3.16 (ecdysone oxidase), EC 1.1.3.17 (choline oxidase), EC 1.1.3.18 (secondary-alcohol oxidase), EC 1.1.3.19 (4-hydroxymandelate oxidase), EC 1.1.3.20 (long-chain alcohol oxidase), EC 1.1.3.21 (glycerol-3-phosphate oxidase), EC 1.1.3.22, EC 1.1.3.23 (thiamine oxidase), EC 1.1.3.24 (L-galactonolactone oxidase), EC 1.1.3.25 , EC 1.1.3.26, EC 1.1.3.27 (hydroxyphytanate oxidase), EC 1.1.3.28 (nucleoside oxidase), EC 1.1.3.29 39 59768580.3Attorney Docket No.278925-561797 (Nacylhexosamine oxidase), EC 1.1.3.30 (polyvinyl alcohol oxidase), EC 1.1.3.31, EC 1.1.3.32, EC 1.1.3.33, EC 1.1.3.34, EC 1.1.3.35, EC 1.1.3.36, EC 1.1.3.37 D-arabinono-l,4- lactone oxidase), EC 1.1.3.38 (vanillyl alcohol oxidase), EC 1.1.3.39 (nucleoside oxidase, H2O2forming), EC 1.1.3.40 (D-mannitol oxidase), or EC 1.1.3.41 (xylitol oxidase).

[0190] In some embodiments, an herbicide enhancer composition comprises a freeradical-producing (FRP) enzymes in one of the sequential components of the herbicide enhancer compositions. In some embodiments, the FRP is a peroxidase. Peroxidases are widely found in biological systems and form a subset of oxidoreductases that reduce hydrogen peroxide (H2O2) to water in order to oxidize a large variety of aromatic compounds ranging from phenol to aromatic amines.

[0191] In some embodiments, an herbicide enhancer composition comprises aperoxidase belonging to the sub-genus EC 1.11.1. In certain embodiments, the EC 1.11.1 enzyme is a peroxidase. In some embodiments, the EC 1.11.1 enzyme can be more specifically, for example, EC 1.11.1.1 (NADH peroxidase), EC 1.11.1.2 (NADPH peroxidase), EC 1.11.1.3 (fatty acid peroxidase), EC 1.11.1.4, EC 1.11.1.5 (cytochrome-c peroxidase), EC 1.11.1.6 (catalase), EC 1.11.1.7 (peroxidase), EC 1.11.1.8 (iodide peroxidase), EC 1.11.1.9 (glutathione peroxidase), EC 1.11.1.10 (chloride peroxidase), EC 1.11.1.11 (L-ascorbate peroxidase), EC 1.11.1.12 (phospholipid-hydroperoxide glutathione peroxidase), EC 1.11.1.13 (manganese peroxidase), EC 1.11.1.14 (diarylpropane peroxidase), or EC 1.11.1.15 (peroxiredoxin).

[0192] In other embodiments, the peroxidase may also be further specified byfunction, e.g., a lignin peroxidase, manganese peroxidase, or versatile peroxidase. The peroxidase may also be specified as a fungal, microbial, animal, or plant peroxidase. The peroxidase may also be specified as a class I, class II, or class III peroxidase. The peroxidase may also be specified as a myeloperoxidase (MPO), eosinophil peroxidase (EPO), lactoperoxidase (LPO), thyroid peroxidase (TPO), prostaglandin H synthase (PGHS), glutathione peroxidase, haloperoxidase, catalase, cytochrome c peroxidase, horseradish peroxidase, peanut peroxidase, soybean peroxidase, turnip peroxidase, tobacco peroxidase, tomato peroxidase, barley peroxidase, or peroxidasin. In these particular embodiments, the peroxidase is a lactoperoxidase.

[0193] The present disclosure provides foliar crop protection products that arebiocatalytically generated by enzymes (referred to as ZX). The inventors surprisingly found that an increased ratio of thiocyanate (e.g. KSCN) over iodide (e.g. KI) provides increased 40 59768580.3Attorney Docket No.278925-561797 injury or desiccation in plants. In some embodiments, the KSCN alone is used to injure or desiccate the plants.

[0194] In some embodiments, an herbicide enhancer composition can be an iodine-thiocyanate-based herbicide enhancer that may have no herbicidal activity alone, but work with commercially available herbicides to eliminate weeds with and act as “burn-down” desiccants for agronomical or agricultural field operations. In some embodiments, the herbicide enhancer compositions of the present disclosure, when mixed with commercial herbicides, have a greater than additive herbicidal effect and are active on a broad range of crops. The disclosure further provides a production process wherein, in some embodiments, either the solid chemical precursors and / or lyophilized enzymes are reconstituted in water in tank mixers and mixed with a commercial herbicide(s) before application. Alternatively, in some embodiments, the herbicide enhancer compositions can be already mixed with different herbicide active ingredients and reconstituted in water using tank mixers and sprayed. This way, all precursors can be shipped to the end-user (farmer or applicator) as solids. This obviates long-term stability issues during shipment and storage. Upon reconstitution, the solution is stirred and sprayed onto the target plants. During spraying, exposure to oxygen may reignite the enzymatic cascade that provides or further enhances in situ production of bioactive products on leaves.

[0195] In some embodiments, the EX and ZX formulations are produced by a processwherein the solid chemical precursors, and in some embodiments lyophilized enzymes, and in other embodiments, chemical herbicides, are reconstituted in liquids such as water using industry standard tank mixers. In some embodiments, they are mixed the day prior or day of application. Thus, in some embodiments, upon reconstitution, the solution is stirred overnight and sprayed with standard equipment. During spraying, exposure to oxygen may reignite the enzymatic cascade and / or enhance the effects in situ. This may result from the production of herbicidal species on leaves.

[0196] The disclosure provides agents and methods that injure or desiccate farmplants for conventional or no-till farming. Between a crop harvest and planting, a common practice is to plant “cover crops.” These crops increase the soil health and reduce erosion. Often the soil needs to be tilled to remove the cover crop and prepare the soil for the commercial crop. An alternative or aid to tilling is to treat the cover crops with “burn-down” agents that injure or desiccate the cover crops. Traditional burn-down agents include environmentally unfriendly agents such as paraquat and glyphosate (i.e. Roundup®). These agents can potentially contaminate the soil and water. The disclosure provides an 41 59768580.3Attorney Docket No.278925-561797 environmentally friendly alternative that does not accumulate in soil and water. Furthermore, tilling is environmentally unfriendly because it releases carbon from the soil and uses fossil fuels during tillage operations.

[0197] The agents and methods of the disclosure are beneficial for injuring ordesiccating plants to assist in mechanical harvesting. Some products such as potatoes, and small grains are harvested mechanically so reducing the foliage makes that process more efficient.

[0198] The innovations and tools disclosed herein enable efficient and economicalfarm operations typically associated with harvesting or no-till planting. They reduce the amount of active chemical herbicides applied in the field. This technology improves crop yields and reduces environmental impacts. The tools reduce agrochemical dosage rates of conventional registered products needed to effectively manage weeds and thus decreases the likelihood of resistance development in diverse plant species. Simultaneously, they provide an effective method for managing harvest operations and planting in major crop production systems. In some embodiments, the compositions are dormant and become active upon exposure to hydration, oxygen, and / or mixing.

[0199] Thus, the disclosure provides new iodide-, thiocyanate-, and iodide-thiocyanate-based herbicide enhancer (EX) compositions that are combined with one or more chemical herbicides, and herbicide (ZX) formulations that eliminate weeds and act as a “burn-down” desiccant for agricultural field operations. The herbicidal combination compositions and ZX formulations are active on a broad range of crops, broadleaf weeds, grasses, and sedges.

[0200] In various embodiments, the herbicide enhancer compositions of the presentdisclosure do not possess herbicidal activity against plants, or parts thereof, or weeds or crops as exemplified herein, or at most has less than 5% herbicidal activity, less than 4% herbicidal activity, less than 3% herbicidal activity, less than 2% herbicidal activity, less than 1% herbicidal activity, or has 0% herbicidal activity when combined with one or more chemical herbicides disclosed herein, or an agrochemically acceptable salt thereof, when calculated using the Colby Formula.

[0201] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, and at least one adjuvant, excipient, diluent and / or carrier.

[0202] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an 42 59768580.3Attorney Docket No.278925-561797 amount ranging from about 1 mM to about 100 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0203] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0204] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and at least one adjuvant, excipient, diluent and / or carrier.

[0205] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; and at least one adjuvant, excipient, diluent and / or carrier.

[0206] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM, KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0207] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM, KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0208] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and at least one adjuvant, excipient, diluent and / or carrier.

[0209] In some embodiments, a herbicide enhancer composition comprises KI, athiocyanate salt, and at least one adjuvant, excipient, diluent and / or carrier.

[0210] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, and at least one adjuvant, excipient, diluent and / or carrier. 43 59768580.3Attorney Docket No.278925-561797

[0211] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0212] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and at least one adjuvant, excipient, diluent and / or carrier.

[0213] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, KSCN, and at least one adjuvant, excipient, diluent and / or carrier.

[0214] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, KSCN in an amount ranging from about 1 mM to about 100 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0215] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, KSCN in an amount ranging from about 5 mM to about 80 mM, and at least one adjuvant, excipient, diluent and / or carrier.

[0216] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and at least one adjuvant, excipient, diluent and / or carrier.

[0217] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a sugar, and at least one adjuvant, excipient, diluent, and / or carrier.

[0218] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a sugar, e.g., a monosaccharide or a disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0219] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a monosaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier. 44 59768580.3Attorney Docket No.278925-561797

[0220] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a sugar, e.g., a monosaccharide or a disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0221] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0222] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0223] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0224] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose; and at least one adjuvant, excipient, diluent, and / or carrier.

[0225] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, glucose, fructose, galactose, or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0226] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose, galactose, or sucrose in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0227] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, glucose, fructose, galactose, or sucrose in an 45 59768580.3Attorney Docket No.278925-561797 amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0228] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0229] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose, galactose, or sucrose in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0230] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, glucose, fructose, galactose, or sucrose in an amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0231] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0232] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, glucose, fructose, galactose, or sucrose, or a combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0233] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0234] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount 46 59768580.3Attorney Docket No.278925-561797 ranging from about 5 mM to about 80 mM, glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0235] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0236] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose, galactose, or sucrose, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0237] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0238] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0239] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier. 47 59768580.3Attorney Docket No.278925-561797

[0240] In some embodiments, a herbicide enhancer composition comprises KI, athiocyanate salt, glucose, fructose, galactose, or sucrose, or any combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0241] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0242] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0243] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0244] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, KSCN, glucose, fructose, galactose, or sucrose, or any combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0245] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0246] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier. 48 59768580.3Attorney Docket No.278925-561797

[0247] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose, galactose, or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one excipient.

[0248] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a monosaccharide, and at least one adjuvant, excipient, diluent, and / or carrier.

[0249] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a monosaccharide, and at least one adjuvant, excipient, diluent, and / or carrier.

[0250] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a monosaccharide, and at least one adjuvant, excipient, diluent, and / or carrier.

[0251] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide; and at least one adjuvant, excipient, diluent, and / or carrier.

[0252] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0253] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0254] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a monosaccharide, e.g., glucose, fructose, 49 59768580.3Attorney Docket No.278925-561797 galactose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0255] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0256] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0257] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0258] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, glucose, fructose or sucrose, and at least one adjuvant, excipient, diluent, and / or carrier.

[0259] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose; and at least one adjuvant, excipient, diluent, and / or carrier.

[0260] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a monosaccharide, and at least one adjuvant, excipient, diluent, and / or carrier.

[0261] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a monosaccharide in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0262] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount 50 59768580.3Attorney Docket No.278925-561797 ranging from about 5 mM to about 80 mM, a monosaccharide in an amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0263] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0264] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0265] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0266] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0267] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0268] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, glucose, fructose or sucrose, or a combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0269] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, glucose, fructose or sucrose, or a 51 59768580.3Attorney Docket No.278925-561797 combination thereof in an amount of about 10 mM to about 100 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0270] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM, and at least one adjuvant, excipient, diluent, and / or carrier.

[0271] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0272] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0273] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0274] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0275] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of 52 59768580.3Attorney Docket No.278925-561797 about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0276] In some embodiments, a herbicide enhancer composition comprises KI, athiocyanate salt, glucose, fructose or sucrose, or any combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0277] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0278] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0279] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0280] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, KSCN, glucose, fructose or sucrose, or any combination thereof, and at least one adjuvant, excipient, diluent, and / or carrier.

[0281] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0282] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof 53 59768580.3Attorney Docket No.278925-561797 in an amount of about 20 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0283] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; and at least one excipient.

[0284] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0285] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0286] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0287] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0288] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, a thiocyanate salt, a monosaccharide, a pH buffer, and at least one adjuvant, excipient, diluent, and / or carrier.

[0289] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; a monosaccharide in an amount of about 54 59768580.3Attorney Docket No.278925-561797 10 mM to about 100 mM; a pH buffer salt in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0290] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; a monosaccharide in an amount of about 20 mM to about 50 mM; a pH buffer salt in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0291] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; a pH buffer salt in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0292] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof; a pH buffer; and at least one adjuvant, excipient, diluent, and / or carrier.

[0293] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 10 mM to about 100 mM; a pH buffer salt in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0294] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 20 mM to about 50 mM; a pH buffer salt in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0295] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a monosaccharide, e.g., glucose, fructose, galactose, or combinations thereof in an amount of about 6 mM, about 6.25 mM, about 10 55 59768580.3Attorney Docket No.278925-561797 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; a pH buffer salt in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0296] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; and at least one adjuvant, excipient, diluent, and / or carrier.

[0297] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0298] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0299] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0300] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; and at least one adjuvant, excipient, diluent, and / or carrier.

[0301] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier. 56 59768580.3Attorney Docket No.278925-561797

[0302] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0303] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0304] In some embodiments, a herbicide enhancer composition comprises KI; athiocyanate salt; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; and at least one adjuvant, excipient, diluent, and / or carrier.

[0305] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0306] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0307] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, 57 59768580.3Attorney Docket No.278925-561797 about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0308] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; KSCN; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; and at least one adjuvant, excipient, diluent, and / or carrier.

[0309] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0310] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0311] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0312] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; an enzyme, e.g., a hydrogen peroxide producing enzyme, a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate, or any combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0313] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; an enzyme, e.g., a hydrogen peroxide producing enzyme, for example, an oxidase, for example, a glucose oxidase (Gox), a FRP enzyme, for example, a peroxidase 58 59768580.3Attorney Docket No.278925-561797 operable to catalyze hydrogen peroxide, iodide, and thiocyanate, or any combination thereof, e.g., an oxidase, e.g., glucose oxidase, a peroxidase, e.g., lactoperoxidase, or any combination thereof; and at least one adjuvant, excipient, diluent, and / or carrier.

[0314] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., a hydrogen peroxide producing enzyme, a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate, or any combination thereof, e.g., an oxidase, e.g., glucose oxidase, a peroxidase, e.g., lactoperoxidase, or any combination thereof in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0315] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., a hydrogen peroxide producing enzyme, a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate, or any combination thereof, e.g., an oxidase, e.g., glucose oxidase, a peroxidase, e.g., lactoperoxidase, or any combination thereof in an amount of about 3 U / mL to about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0316] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., a hydrogen peroxide producing enzyme, a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate, or any combination thereof, e.g., an oxidase, e.g., glucose oxidase, a peroxidase, e.g., lactoperoxidase, or any combination thereof in an amount of about 3 U / mL, about 4 U / mL, about 5 U / mL, about 10 U / mL, about 12 U / mL, about 20 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0317] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; a hydrogen peroxide producing enzyme; and at least one adjuvant, excipient, diluent, and / or carrier.

[0318] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; a hydrogen peroxide producing enzyme; and at least one adjuvant, excipient, diluent, and / or carrier.

[0319] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a hydrogen peroxide producing 59 59768580.3Attorney Docket No.278925-561797 enzyme in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0320] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a hydrogen peroxide producing enzyme in an amount of about 3 U / mL to about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0321] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a hydrogen peroxide producing enzyme in an amount of about 3 U / mL, about 4 U / mL, about 5 U / mL, about 10 U / mL, about 12 U / mL, about 20 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0322] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate; and at least one adjuvant, excipient, diluent, and / or carrier.

[0323] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate; and at least one adjuvant, excipient, diluent, and / or carrier.

[0324] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0325] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate in an amount of about 3 U / mL to about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0326] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; a peroxidase operable to catalyze hydrogen peroxide, iodide, and thiocyanate in an amount of about 3 U / mL, about 4 U / mL, about 5 U / mL, about 10 U / mL, about 12 U / mL, about 20 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier. 60 59768580.3Attorney Docket No.278925-561797

[0327] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; glucose oxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0328] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0329] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0330] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0331] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; lactoperoxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0332] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0333] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0334] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0335] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, 61 59768580.3Attorney Docket No.278925-561797 NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; glucose oxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0336] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0337] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0338] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0339] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, for example, KI; a thiocyanate salt; a sugar, for example, a monosaccharide for example, glucose, fructose or a disaccharide, for example, sucrose, or any combination thereof; NaH2PO4; glucose oxidase; and at least one excipient.

[0340] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 62 59768580.3Attorney Docket No.278925-561797 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0341] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0342] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0343] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt, for example, KSCN; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; glucose oxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0344] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; a sugar, for example, a monosaccharide for example, glucose, fructose or a disaccharide, for example, sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL at least one excipient.

[0345] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier. 63 59768580.3Attorney Docket No.278925-561797

[0346] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0347] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; a FRP enzyme, for example, a peroxidase, for example, a lactoperoxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0348] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; a sugar, for example, a monosaccharide for example, glucose, fructose or a disaccharide, for example, sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0349] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; a sugar, for example, a monosaccharide for example, glucose, fructose or a disaccharide, for example, sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0350] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, 64 59768580.3Attorney Docket No.278925-561797 about or about 80 mM; a sugar, for example, a monosaccharide for example, glucose, fructose or a disaccharide, for example, sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0351] In some embodiments, a herbicide enhancer composition comprises KI; athiocyanate salt; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; a FRP enzyme, for example, a peroxidase, for example, a lactoperoxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0352] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0353] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0354] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0355] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; KSCN; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; a FRP 65 59768580.3Attorney Docket No.278925-561797 enzyme, for example, a peroxidase, for example, a lactoperoxidase; and at least one adjuvant, excipient, diluent, and / or carrier.

[0356] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0357] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0358] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; and at least one adjuvant, excipient, diluent, and / or carrier.

[0359] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0360] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0361] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., an oxidase, e.g., glucose oxidase, a peroxidase, e.g., lactoperoxidase, or any combination thereof; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier. 66 59768580.3Attorney Docket No.278925-561797

[0362] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., glucose oxidase, lactoperoxidase, or any combination thereof; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0363] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., glucose oxidase, lactoperoxidase, or any combination thereof in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0364] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., glucose oxidase, lactoperoxidase, or any combination thereof in an amount of about 3 U / mL to about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0365] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; an enzyme, e.g., glucose oxidase, lactoperoxidase, or any combination thereof in an amount of about 3 U / mL, about 4 U / mL, about 5 U / mL, about 10 U / mL, about 12 U / mL, about 20 U / mL, or about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0366] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0367] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0368] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0369] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; glucose oxidase in an amount of 67 59768580.3Attorney Docket No.278925-561797 about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0370] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer, e.g., a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, an amino acid-based buffer, or a combination thereof; lactoperoxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0371] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0372] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0373] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; a thiocyanate salt; a monosaccharide; a pH buffer; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0374] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; glucose oxidase; ; hydrogen peroxide (H2O2); and at least one excipient.

[0375] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide 68 59768580.3Attorney Docket No.278925-561797 (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0376] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0377] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0378] In some embodiments, a herbicide enhancer composition comprises KI; athiocyanate salt; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; glucose oxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0379] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0380] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging 69 59768580.3Attorney Docket No.278925-561797 from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0381] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0382] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; KSCN; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; glucose oxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0383] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; glucose oxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0384] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; glucose oxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier. 70 59768580.3Attorney Docket No.278925-561797

[0385] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; glucose oxidase in an amount of about 4 U / mL, about 5 U / mL, about 10 U / mL, or 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0386] In some embodiments, a herbicide enhancer composition comprises an iodidesalt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; glucose, fructose or sucrose, or a combination thereof; NaH2PO4; lactoperoxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0387] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0388] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0389] In some embodiments, a herbicide enhancer composition comprises KI, NaI,NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, 71 59768580.3Attorney Docket No.278925-561797 about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or a combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0390] In some embodiments, a herbicide enhancer composition comprises KI; athiocyanate salt; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; lactoperoxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0391] In some embodiments, a herbicide enhancer composition comprises an KI inan amount ranging from about 0.01 mM to about 10 mM; a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0392] In some embodiments, a herbicide enhancer composition comprises KI in anamount ranging from about 0.1 mM to about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4 in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0393] In some embodiments, a herbicide enhancer composition comprises KI in anamount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4 in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of 72 59768580.3Attorney Docket No.278925-561797 about 3 U / mL, about 12 U / mL, or about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0394] In some embodiments, a herbicide enhancer composition comprises an iodidesalt; KSCN; glucose, fructose or sucrose, or any combination thereof; NaH2PO4; lactoperoxidase; hydrogen peroxide (H2O2); and at least one adjuvant, excipient, diluent, and / or carrier.

[0395] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.01 mM to about 10 mM; KSCN in an amount ranging from about 1 mM to about 100 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 10 mM to about 100 mM; NaH2PO4 in an amount of about 1 mM to about 50 mM; lactoperoxidase in an amount of about 0.1 U / mL to about 50 U / mL; hydrogen peroxide (H2O2) in an amount of about 0.001 mM to about 50 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0396] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount ranging from about 0.1 mM to about 5 mM; KSCN in an amount ranging from about 5 mM to about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 20 mM to about 50 mM; NaH2PO4in an amount of about 5 mM to about 30 mM; lactoperoxidase in an amount of about 3 U / mL to about 20 U / mL; hydrogen peroxide (H2O2) in an amount of about 2 mM to about 20 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0397] In some embodiments, a herbicide enhancer composition comprises an iodidesalt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; glucose, fructose or sucrose, or any combination thereof in an amount of about 6 mM, about 6.25 mM, about 10 mM, about 20 mM, about 35 mM, about 40 mM, or about 50 mM; NaH2PO4in an amount of about 5 mM, about 10 mM, about 15 mM, about 20 mM, or about 30 mM; lactoperoxidase in an amount of about 3 U / mL, about 12 U / mL, or about 25 U / mL; hydrogen peroxide (H2O2) in an amount of about 6 mM, about 7 mM, about 8 mM, about 9 mM, about 10 mL, about 11 mM, about 12 mM, about 13 mM, about 14 mM, or about 15 mM; and at least one adjuvant, excipient, diluent, and / or carrier.

[0398] HERBICIDAL COMBINATION COMPOSITIONS73 59768580.3Attorney Docket No.278925-561797

[0399] The present disclosure contemplates herbicidal combinations and their use incontrolling plants or inhibiting plant growth. Thus, in some embodiments, the combinations and methods of using the same described herein provide herbicidal mixtures which are highly effective against various weed species (particularly at low dose), and is based on the finding that the enhancer compositions of the present disclosure, in combination with herbicides having the modes of action as specified herein, are particularly efficacious at mediating such weed control.

[0400] The disclosure provides novel management tools for farm operations thatutilize herbicides, defoliants, or desiccants to kill and dry down actively growing plant tissue. This enables efficient and economical farm operations typically associated with harvesting using either conventional or no-till planting techniques. The disclosure provides enhancers for diverse chemical herbicides that significantly reduce the amount of the chemical herbicides that are applied to plants. By increasing chemical efficiency, the enhancers also reduce variability and the amount of chemicals needed. Furthermore, the enhancers result in less re-growth of the target plants. Moreover, the enhancers can be used in “over the top” applications to the plants. They are compatible with crops that are resistant to herbicides such as glufosinate and 2,4-D choline salt. In some embodiments, the crops are genetically- modified to be herbicide-resistant.

[0401] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition of the present disclosure; and (B) one or more chemical herbicide, or agrochemically acceptable salts thereof.

[0402] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition of the present disclosure; and (B) two or more chemical herbicide, or agrochemically acceptable salts thereof.

[0403] In some embodiments, a greater than additive herbicidal effect can beobserved when applying a combination comprising (A) an herbicide enhancer composition of the present disclosure, and (B) one or more chemical herbicide, or agrochemically acceptable salts thereof. A greater than additive herbicidal effect can be determined using the Colby formula, as described herein.

[0404] In some embodiments, herbicidal combination compositions can include acombination of (A) an herbicide enhancer composition as described herein in admixture with, or formulated separately with (B) one or more chemical herbicides as described herein. In some embodiments, the herbicidal combination compositions comprises (A) and (B) or their 74 59768580.3Attorney Docket No.278925-561797 agrochemically acceptable salts thereof, along with one or more formulation adjuvants, excipients, diluents or carriers in a single formulation.

[0405] In some embodiments, herbicidal combination compositions can include (A)an herbicide enhancer composition as described herein along optionally with one or more formulation adjuvants, excipients, diluents or carriers, all of the foregoing formulated in a single formulation, in a first composition, and (B) one or more chemical herbicides, each of the one or more chemical herbicides formulated in single or separate compositions, each chemical herbicide singly, or in admixture, optionally containing one or more formulation adjuvants, excipients, diluents or carriers, wherein (A) and (B) are applied to a plant or a plant locus thereof, weed, or crop concurrently or sequentially (before or after).

[0406] Illustrative chemical herbicides of the present disclosure are shown in the tablebelow.

[0407] Table A. Illustrative chemical herbicides.Herbicide Active Ingredient CAS No. Trade Name75 59768580.3Attorney Docket No.278925-561797

[0408] In some embodiments, the present disclosure provides methods of (i)inhibiting plant growth, and (ii) controlling plants, for example, weeds (monocot weeds and dicot weeds), crops, grasses and hedges, said methods comprising applying to the plants or to the locus thereof: (A) an herbicide enhancer composition and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof.

[0409] In some embodiments, the present disclosure provides a method of controllinggrasses and / or weeds (monocot weeds and dicot weeds) present adjacent to cultivated crops of useful plants which comprises applying to the useful plants or locus thereof or to the area of cultivation an herbicidally effective amount of (A) an herbicide enhancer composition and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof.

[0410] When active ingredients are combined, the activity to be expected (E) for anygiven active ingredient combination obeys the so-called Colby Formula and can be calculated as follows (Colby, S. R., Calculating synergistic and antagonistic responses of herbicide combination, Weeds, Vol.15, pages 20-22; 1967):

[0411] ppm = milligrams of active ingredient (a.i.) per liter

[0412] X = % action by first active ingredient using p ppm of the active ingredient

[0413] Y = % action by second active ingredient using q ppm of the active ingredient.

[0414] According to Colby, the expected action of active ingredients A + B using p +q ppm of active ingredient is represented by the following formula: E = X + Y – ((X * Y) / 100).

[0415] If the action actually observed (O) is greater than the expected action E thenthe action of the combination is greater than additive. In mathematical terms, a greater than additive effect corresponds to a positive value for the difference of (O – E). In the case of purely complementary addition of activities (expected activity), said difference (O – E) is zero. A negative value of said difference (O – E) signals a loss of activity compared to the expected activity.

[0416] In some embodiments, some of the chemical herbicides of component B arecommonly used in the form of agronomically acceptable salts. Where a specific herbicide is described as being suitable for use as component B, a person of ordinary skill will appreciate that this includes any suitable agronomically acceptable salt of that herbicide, for example any salt which may form with amines (for example ammonia, dimethylamine and triethylamine), alkali metal and alkaline earth metal bases or quaternary ammonium bases. 76 59768580.3Attorney Docket No.278925-561797 Among the alkali metal and alkaline earth metal hydroxides, oxides, alkoxides and hydrogen carbonates and carbonates used as salt formers, emphasis is to be given to the hydroxides, alkoxides, oxides and carbonates of lithium, sodium, potassium, magnesium and calcium, but especially those of sodium, magnesium and calcium. The corresponding trimethylsulfonium salt may also be used. The present disclosure also include the use of hydrates which may be formed during the salt formation for any herbicide of component B.

[0417] In some embodiments, a greater than additive herbicidal effect can beobserved when applying a combination comprising (A) an herbicide enhancer composition of the present disclosure, and (B) one or more chemical herbicide, or agrochemically acceptable salts thereof.

[0418] In some embodiments, a greater than additive effect of (A) an herbicideenhancer composition of the present disclosure, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof, can be observed, for example, in the case of a ready- mix application, for example as a ready-to-use (RTU) formulation, emulsifiable concentrate (EC) formulation, microemulsifiable concentrate, oil dispersion (OD) formulation, wettable powder (WP) formulation, water dispersible granule (WG), water soluble granule (SG) formulation. In some embodiments, a greater than additive effect can be observed when the active compounds are applied at different times (splitting) (packed, for example, as combipack or monodoses). It is also possible to apply the (A) herbicide enhancer composition of the present disclosure, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof, in a plurality of portions (sequential application), for example post- emergence applications or early post-emergence applications followed by medium or late post-emergence applications.

[0419] In some embodiments, the greater than additive effect of a combination of: (A)an herbicide enhancer composition of the present disclosure, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof, permits a reduction of the application rates of the individual components of (A) an herbicide enhancer composition of the present disclosure, or (B) one or more chemical herbicides, or agrochemically acceptable salts thereof, a higher and / or longer efficacy at the same application rate, the control of species which were as yet uncontrolled (gaps), control of species which are tolerant or resistant to individual herbicides or to a number of herbicides, an extension of the period of application and / or a reduction in the number of individual applications required and, as a result for the user, unwanted vegetation control systems which are more advantageous economically and ecologically. 77 59768580.3Attorney Docket No.278925-561797

[0420] The herbicidal combination compositions of the disclosure can also bemeasured by their EC50. The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is used herein as a measure of herbicidal potency. The EC50 of a graded dose response curve therefore represents the concentration of a compound where 50% of its maximal effect is observed. The EC50of a quantal dose response curve represents the concentration of a compound where 50% of the population exhibit a response after a specified exposure duration. The herbicides of the disclosure are at a final concentration of less than 1% or about 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%. In other embodiments, the final chemical concentration is between about 100% and 500%, 500% and 1000%, 1000% and 2000%, 2000% and 2500%, 2500% and 5000%, 5000% and 10,000%.

[0421] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula.

[0422] In some embodiments, the chemical herbicide comprised within the herbicidalcombination composition is Glufosinate, Glufosinate-ammonium, L-glufosinate (L- configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, Glyphosate, Flumioxizan, Paraquat, Sufentrazone, Carfentrazone, Dicamba, Dimethylamine Salt of Dicamba, 2,4-Dichlorophenoxyacetic acid, Triclopyr, Imazapyr, Oxyfluorfen, Diquat, Tralkoxydim, Fluazifop-B-Butyl, Atrazine, Nicosulfuron, Rimsulfuron, Bentazon, Ammonium nonanoate, Ammonium salt of imazamox, Cumyluron, Diflufenican, Dimethylamine Salt of 2,4-D, Dimethylamine Salt of MCPA (2-methyl-4- chlorophenoxyacetic acid), Epyrifenacil, Ethofumesate, Halosulfuron-methyl, Imazethapyr- ammonium, Mesotrione, Metamitron, Metsulfuron-methyl, Pyraclonil, Quinclorac, Saflufenacil, Sulfentrazone, Trifludimoxazin, Imazapyr Aminocyclopyrachlor, Metsulfuron, Triclopyr amine, Capric acids, caprylic acids, or any combination thereof.

[0423] In some embodiments, the chemical herbicide comprised within the herbicidalcombination composition is: glufosinate-ammonium or glufosinate-P-ammonium or 2-amino- 4-(hydroxymethylphosphinyl) butanoic acid-monoammonium salt; diglycolamine salt of dicamba or benzoic acid, 3,6-dichloro-2-methoxy-, compound with 2-(2-aminoethoxy) ethanol (1:1); triclopyr or (3,5,6-trichloro-2-pyridinyl)oxyacetic acid, triethylamine salt; 78 59768580.3Attorney Docket No.278925-561797 carfentrazone-ethyl or ethyl (RS)-2-chloro-3-[2-chloro-5-(4-difluoromethyl-4,5-dihydro-3- methyl-5-oxo-1H-1,2,4-triazol-1-yl)-4-fluorophyenyl]proprionate; flumioxazin or N-(7- fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2- dicarboxamide; sulfentrazone or 2′,4′-dichloro-5′-(4-difluoromethyl-4,5-dihydro-3-methyl-5- oxo-1H-1,2,4-triazol-1-yl) methanesulfonanilide; paraquat or 1,1'-Dimethyl-4,4'-bipyridinium dichloride; glufosinate ammonium or 2-amino-4-[hydroxy(methyl)phosphoryl]butanoate; 2,4- dichlorophenoxyacetic acid, choline salt or 2-(2,4-dichlorophenoxy)acetate;2- hydroxyethyl(trimethyl)azanium; chlorothalonil or 2,4,5,6-tetrachlorobenzene-1,3- dicarbonitrile; spinetoram or 3'-ethyl-5,6-dihydrospinosyn J and 3'-ethoxy-spinosyn L; pyraclostrobin or carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3- yl]oxy]methyl]phenyl]methoxy-, methyl ester; 2,4-dichlorophenoxyacetic acid, choline salt or 2-(2,4-dichlorophenoxy)acetate;2-hydroxyethyl(trimethyl)azanium; glyphosate or N- (phosphonomethyl)glycine potassium salt; diglycolamine salt of 3,6-dichloro-o-anisic acid; and tryclopyr (3,5,6-trichloro-2-pyridinyl) oxyacetic acid triethylamine salt, Glufosinate, Glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, Glyphosate, Flumioxizan, Paraquat, Sufentrazone, Carfentrazone, Dicamba, Dimethylamine Salt of Dicamba, 2,4-Dichlorophenoxyacetic acid, Triclopyr, Imazapyr, Oxyfluorfen, Diquat, Tralkoxydim, Fluazifop-B-Butyl, Atrazine, Nicosulfuron, Rimsulfuron, Bentazon, Ammonium nonanoate, Ammonium salt of imazamox, Cumyluron, Diflufenican, Dimethylamine Salt of 2,4-D, Dimethylamine Salt of MCPA (2- methyl-4-chlorophenoxyacetic acid), Epyrifenacil, Ethofumesate, Halosulfuron-methyl, Imazethapyr-ammonium, Mesotrione, Metamitron, Metsulfuron-methyl, Pyraclonil, Quinclorac, Saflufenacil, Sulfentrazone, Trifludimoxazin, Imazapyr Aminocyclopyrachlor, Metsulfuron,Triclopyr amine, Capric acids, caprylic acids .

[0424] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is glufosinate.

[0425] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is glufosinate-ammonium or glufosinate-P-ammonium or 2-amino-4- (hydroxymethylphosphinyl) butanoic acid-monoammonium salt.

[0426] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is diglycolamine salt of dicamba or benzoic acid, 3,6-dichloro-2-methoxy-, compound with 2-(2-aminoethoxy) ethanol (1:1).

[0427] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is triclopyr or (3,5,6-trichloro-2-pyridinyl)oxyacetic acid, triethylamine salt. 79 59768580.3Attorney Docket No.278925-561797

[0428] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is carfentrazone-ethyl or ethyl (RS)-2-chloro-3-[2-chloro-5-(4-difluoromethyl- 4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)-4-fluorophyenyl]proprionate.

[0429] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is flumioxazin or N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4- benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide; sulfentrazone or 2′,4′-dichloro-5′-(4- difluoromethyl-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl) methanesulfonanilide.

[0430] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is paraquat or 1,1'-Dimethyl-4,4'-bipyridinium dichloride.

[0431] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is glufosinate ammonium or 2-amino-4-[hydroxy(methyl)phosphoryl]butanoate.

[0432] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is 2,4-dichlorophenoxyacetic acid, choline salt or 2-(2,4- dichlorophenoxy)acetate;2-hydroxyethyl(trimethyl)azanium.

[0433] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is chlorothalonil or 2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile.

[0434] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is spinetoram or 3'-ethyl-5,6-dihydrospinosyn J and 3'-ethoxy-spinosyn L.

[0435] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is pyraclostrobin or carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3- yl]oxy]methyl]phenyl]methoxy-, methyl ester.

[0436] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is glyphosate or N-(phosphonomethyl)glycine potassium salt.

[0437] In some embodiments, the chemical herbicide comprised within the herbicidecomposition is diglycolamine salt of 3,6-dichloro-o-anisic acid.

[0438] The disclosure provides naturally derived herbicides (ZX herbicides) thateliminate undesirable plants. The disclosure further provides methods for their use. They result in improved crop yields and reduced environmental impacts due to reduced or eliminated chemical herbicides or the combination of broad spectrum non-selective herbicidal activities and limited soil persistence. When used as a co-formulant, EX enhancers reduced agrochemical dosage rates of conventional registered products needed to effectively manage plants such as weeds. This decreases resistance development in diverse plant species and provides an alternative, effective method for managing harvest operations and planting in major crop production systems. 80 59768580.3Attorney Docket No.278925-561797

[0439] The disclosure provides enhancer compositions (EX herbicide enhancers) andmethods for their use. When used or applied in conjunction with chemical herbicide, they enhance the biological performance of the chemical herbicides on the target plants. In some embodiments, the enhancers enable a reduced application rate of the chemical herbicides while providing desired agronomic efficacy (biological performance) on the target plants.

[0440] The herbicide enhancers as disclosed herein may have different modes ofaction. Without being bound by theory, they may increase herbicide activity or herbicide absorption into plant tissue. They may increase “rainfastness” or decrease photodegradation of herbicides. The herbicide enhancers may be formulated with surfactants, crop oil concentrates, nitrogen fertilizers, spreader-stickers, wetting agents, and penetrants. In some embodiments, potassium thiocyanate destabilizes lipid membranes and disrupts the structure of proteins and nucleic acids (P.M. Dey, M.D. Brownleader, J.B. Harborne, The Plant, the Cell and its Molecular Components, Plant Biochemistry, Academic Press.1-47 (1997), incorporated by reference herein in its entirety). Some herbicides, such as glufosinate, are contact herbicides and have limited translocation within the plant. The EX enhancers may facilitate the movement of the active ingredient through the cell membrane thereby amplifying its effect.

[0441] Glufosinate is a contact herbicide with limited translocation within plants.Less than 3% of applied glufosinate moves to untreated parts of the plant. (Hudson et al., J. Ag. Food Chem.68(10):3026-3032 (2020).) Absorption and translocation are pesticide movement processes after application to a plant. Absorption is the process of pesticide penetration through the leaves. Translocation is the migration of those pesticides to different parts of the plant. Increasing pesticide translocation makes pesticides more effective because they protect the whole plant as opposed to the leaf directly sprayed with the pesticide. Products with systemic effects exist for commercial fungicides and insecticides. For example, Azoxystrobin (the active ingredient in the fungicide Heritage®), triflumizole (the active ingredient in Procure®), and Terraguard®, penetrate the leaf tissue and translocate through the xylem tissue. Neonicotinoids, a class of insecticide compounds, translocate throughout the whole plant and provide systemic protection against insect pests. The herbicide enhancers of the disclosure (EX) dramatically improve herbicides by enhancing their translocation to potentially the entire plant. This may be applied to a broad spectrum of herbicides.

[0442] In some embodiments, the EX herbicide enhancers may enhance the activityor effectiveness of the following herbicides (trade names in parentheses): glufosinate (Basta®, Finale®, Rely®, and Liberty®, HOE 039866, Ignite ISC Herbicide®, HOE 00661); 81 59768580.3Attorney Docket No.278925-561797 L-glufosinate (L-configuration) and / or its salts; L-glufosinate ammonium; L-glufosinate free acid; Mesotrione (Sublime®); glyphosate (Roundup®), flumioxizan (Valor®, Sureguard®, Promenade®, Clipper®, Flumishield®, Flumiguard®); paraquat ( Gramoxone®, Parazone®, Para-Shot 3.0®, Preeglone®, Prelude®, Quik-Quat®, Revolver®, Sweep®); sufentrazone (Spartan®, Solitaire®, Dismiss®); carfentrazone (Aim®, Affinity®, Stingray®); dicamba (Banvel®, Dianat®, Diablo®, Oracle®, Vanguish®); dimethylamine salt of dicamba (Triad Select®); 2,4-dichlorophenoxyacetic acid (i.e.2,4 D, Enlist®, Weedone®, Unison®, Weedar®); dimethylamine salt of 2,4-D (Triad Select®); triclopyr (Garlosn®, Remedy®, Boulder®, Aquasweep®, Crossbow®, Pathfinder®, Sublime®; Triad TZ Select®); imazapyr (Arsenal®, Chopper®, Stalker®, Habitat®, Ecomazapyr®, Polaris®); oxyfluorfen (Goal®, Galigan®); diquat (Aquacide®, Aquakill®, Dextrone®, Diquat®, Reglone®, Reglox®, Reward®, Tag®, Torpedo®, Vegetrole®, and Weedtrine-D®); tralkoxydim (ACHIEVE®; ACHIEVE®-40DG; ALPHA GRASP®; ICI-A 604®; PP 604®; SPLENDOR®); fluazifop- b-butyl (Fusilade 2000®, Fusilade DX®, Fusilade Five®, Fusilade Super®, Fusion®, Horizon®, Ornamec®, PP005®, and Tornado®); atrazine (Aatrex®, Aktikon®, Alazine®, Atred®, Atranex®, Atrataf®, Atratol®, Azinotox®, Crisazina®, Farmco® Atrazine®, G- 30027®, Gesaprim®, Giffex 4L®, Malermais®, Primatol®, Simazat®, and Zeapos®); nicosulfuron (Accent®, Challenger®, Dasul®, Lama®, Milagro®, Mistral®, Motivel®, Nisshin® and Sanson®); rimsulfuron (Cimarron®, Matrix®); bentazon (Basagran®, Bashazon®, Bentazon®, Broadloom®); ammonium nonanoate (Surmise® SpeedPro XT), ammonium salt of imazamox (Imazacast®), cumyluron, diflufenican, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid) (Triad Select®), epyrifenacil, ethofumesate (Ethofumesate Select®), glufosinate-ammonium (Surmise® SpeedPro XT), halosulfuron- methyl (Halo Select®), imazethapyr-ammonium (Surmise® SpeedPro XT), metamitron, metsulfuron-methyl (MSM Select®), pyraclonil, quinclorac (Quinclorac 75 DF Select™; Quintessential®), saflufenacil (Kixor®), sulfentrazone (Triad SFZ Select®), and trifludimoxazin.

[0443] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 2 mM KI and said thiocyanate salt is about 40 mM KSCN. 82 59768580.3Attorney Docket No.278925-561797

[0444] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 2.5 mM KI and said thiocyanate salt is about 40 mM KSCN.

[0445] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 5 mM KI and said thiocyanate salt is about 80 mM KSCN.

[0446] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 1 mM KI and said thiocyanate salt is about 20 mM KSCN.

[0447] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 0.5 mM KI and said thiocyanate salt is about 15 mM KSCN.

[0448] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 5 mM KI and said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0449] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and 83 59768580.3Attorney Docket No.278925-561797 (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 5 mM KI and said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 20 U / mL glucose oxidase, and about 25 U / mL lactoperoxidase.

[0450] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 2 mM KI and said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0451] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 2.5 mM KI and said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 5 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0452] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 2.5 mM KI and said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose and about 10 mM phosphate.

[0453] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 1.0 mM KI and said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose and about 30 mM phosphate.

[0454] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) 84 59768580.3Attorney Docket No.278925-561797 one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said iodide salt is about 0.5 mM KI and said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose and about 30 mM phosphate.

[0455] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0456] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 20 U / mL glucose oxidase, and about 25 U / mL lactoperoxidase.

[0457] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0458] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN.

[0459] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) 85 59768580.3Attorney Docket No.278925-561797 one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 5 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0460] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose and about 10 mM phosphate.

[0461] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose and about 10 mM phosphate.

[0462] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0463] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, and, isolated from Aspergillus niger, about 10 U / mL glucose oxidase and about 12 U / mL lactoperoxidase. 86 59768580.3Attorney Docket No.278925-561797

[0464] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, and, isolated from Penicillium amagasakiense, about 10 U / mL glucose oxidase and about 12 U / mL lactoperoxidase.

[0465] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 6 mM glucose, about 20 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

[0466] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0467] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0468] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, 87 59768580.3Attorney Docket No.278925-561797 said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0469] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 4 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0470] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, and about 4 U / mL glucose oxidase.

[0471] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

[0472] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0473] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect 88 59768580.3Attorney Docket No.278925-561797 weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

[0474] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

[0475] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0476] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

[0477] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, and about 30 mM phosphate.

[0478] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) 89 59768580.3Attorney Docket No.278925-561797 one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0479] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0480] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM fructose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0481] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM fructose and about 30 mM phosphate.

[0482] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 1 mM KI, the thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase. 90 59768580.3Attorney Docket No.278925-561797

[0483] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0484] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 20 mM glucose, about 20 mM fructose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

[0485] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 20 mM glucose, about 20 mM sucrose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0486] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.25 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 30 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0487] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, 91 59768580.3Attorney Docket No.278925-561797 the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0488] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 35 mM glucose, about 5 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0489] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 2 mM KI, the thiocyanate salt is about 40 mM KSCN, further comprising about 20 mM glucose, about 20 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0490] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, and about 6.0 U / mL glucose oxidase.

[0491] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 35 mM glucose, about 5 mM phosphate, and about 6.0 U / mL glucose oxidase.

[0492] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect 92 59768580.3Attorney Docket No.278925-561797 weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, and about 6.0 U / mL glucose oxidase.

[0493] In some embodiments, an herbicidal combination composition comprises: (A)an herbicide enhancer composition as described in any of the above embodiments, and (B) one or more chemical herbicides, or agrochemically acceptable salts thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, wherein the iodide salt is about 0.1 mM KI, the thiocyanate salt is about 5 mM KSCN, further comprising about 50 mM glucose, and about 30 mM phosphate, about 6.0 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

[0494] In various embodiments, the examples of herbicidal combination compositionsdescribed above are formulated to provide greater than additive herbicidal effects. Wherein the foregoing examples can utilize the Colby Formula to determine the greater than additive effects of the herbicidal combination composition versus the herbicide alone, other methods for determining greater than additive effects of two components are known in the art and are applicable herewith. In addition, the time at which the determination of greater than additive effects as provided in the forgoing examples of herbicidal combination compositions can vary between 5 and 30 days, or from 7 to 21 days, of from 10 to 18, days or within 14 days of application of the herbicidal combination composition to a plant, or its locus thereof.

[0495] In some embodiments, the herbicidal combination composition of the presentdisclosure comprises: (A) an herbicide enhancer composition, and (B) one or more chemical herbicides, wherein a weight ratio of components (A) and (B) is about 10,000:1, 5,000:1, 1,000:1, 500:1, 250:1, 200:1, 100:1, 99:1, 95:5, 90:10, 85:15, 80:20, 75:25, 70:30, 65:35, 60:40, 55:45, 1:1, 45:55, 40:60, 35:65, 30:70, 25:75, 20:80, 15:85, 10:90, 5:95, 1:99, 1:100, 1:200, 1:250, 1:500, 1:1,000, 1:5,000, or 1:10,000. For example, the wt% ratio of (A) to (B) in a herbicidal combination composition can range from 10,000:1 to 1:10,000, or from 5,000:1 to 1:5000, or from 1,000:1 to 1:1,000, or from 900:1 to 1:900, or from 800:1 to 1:800, or from 700:1 to 1:700, or from 600:1 to 1:600, or from 500:1 to 1:500, or from 400:1 to 1:400, or from 300:1 to 1:300, or from 200:1 to 1:200, or from 100:1 to 1:100, and all integers therebetween each of the ranges exemplified. All of the exemplified ranges are provided such that the range of components (A) and (B) are present in the herbicidal combination composition in a greater than additive effect weight ratio, as defined by the Colby Formula, or any other more than additive or synergistic calculation formula known in 93 59768580.3Attorney Docket No.278925-561797 the art, for example, when the herbicidal combination composition is applied to a plant or a locus thereof, and such herbicidal effects are measured between 5 and 30 days, or from 7 to 21 days, of from 10 to 18, days or within 14 days of application of the herbicidal combination composition to a plant, or its locus thereof.

[0496] In additional embodiments, the herbicidal combination composition furthercomprises an adjuvant, excipient, diluent or carrier selected from water, toluene, xylene, petroleum ether, vegetable oils, acetone, methyl ethyl ketone, cyclohexanone, acid anhydrides, acetonitrile, acetophenone, amyl acetate, 2-butanone, butylene carbonate, chlorobenzene, cyclohexane, cyclohexanol, alkyl esters of acetic acid, diacetone alcohol, 1,2- dichloro­propane, diethanolamine, p-diethylbenzene, diethylene glycol, diethylene glycol abietate, diethylene glycol butyl ether, diethylene glycol ethyl ether, diethylene glycol methyl ether, N,N-dimethylformamide, dimethyl sulfoxide, 1,4-dioxane, dipropylene glycol, dipropylene glycol methyl ether, dipropylene glycol dibenzoate, diproxitol, alkylpyrrolidone, ethyl acetate, 2-ethylhexanol, ethylene carbonate, 1,1,1-trichloroethane, 2-heptanone, alpha- pinene, d-limonene, ethyl lactate, ethylene glycol, ethylene glycol butyl ether, ethylene glycol methyl ether, ganima-butyrolactone, glycerol, glycerol acetate, glycerol diacetate, glycerol triacetate, hexadecane, hexylene glycol, isoamyl acetate, isobornyl acetate, isooctane, isophorone, isopropylbenzene, isopropyl myristate, lactic acid, laurylamine, mesityl oxide, methoxypropanol, methyl isoamyl ketone, methyl isobutyl ketone, methyl laurate, methyl octanoate, methyl oleate, methylene chloride, m-xylene, n-hexane, n-octylamine, octadecanoic acid, octylamine acetate, oleic acid, oleylamine, a-xylene, phenol, polyethylene glycol, propionic acid, propyl lactate, propylene carbonate, propylene glycol, propylene glycol methyl ether, p-xylene, toluene, triethyl phosphate, triethylene glycol, xylenesulfonic acid, paraffin, mineral oil, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, propylene glycol methyl ether, diethylene glycol methyl ether, methanol, ethanol, isopropanol, and alcohols of higher molecular weight, such as amyl alcohol, tetrahydrofurfuryl alcohol, hexanol, octanol, ethylene glycol, propylene glycol, glycerol, N- methyl-2-pyrrolidone, talc, titanium dioxide, pyrophyllite clay, silica, attapulgite clay, kieselguhr, limestone, calcium carbonate, bentonite, calcium montmorillonite, cottonseed husks, wheat flour, soybean flour, pumice, wood flour, ground walnut shells, lignin, salts of alkyl sulfates such as diethanolanimonium lauryl sulfate, salts of alkylarylsulfonates such as calcium dodecylbenzenesulfonate, alkylphenol / alkylene oxide addition products such as nonylphenol ethoxylate, alcohol / alkylene oxide addition products such as tridecylalcohol ethoxylate, soaps such as sodium stearate, salts of alkylnaphthalenesulfonates such as sodium 94 59768580.3Attorney Docket No.278925-561797 dibutylnaphthalenesulfonate, dialkyl esters of sulfosuccinate salts such as sodium di(2- ethylhexyl)sulfosuccinate, sorbitol esters such as sorbitol oleate, quaternary amines such as lauryltrimethylammonium chloride, polyethyleneglycol esters of fatty acids such as polyethylene glycol stearate, block copolymers of ethylene oxide and propylene oxide, and salts of mono- and di-alkylphosphate esters, and combinations thereof.

[0497] In some embodiments, an herbicidal combination composition compriseshydrogen peroxide (H2O2) and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant.

[0498] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution.

[0499] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, and wherein said iodide salt is KI, NaI, or NH4I.

[0500] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, and wherein said iodide salt is KI.

[0501] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, wherein said iodide salt is KI, NaI, or NH4I, and wherein said iodide salt has a concentration of about 18 mM.

[0502] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, wherein said iodide salt is KI, and wherein said iodide salt has a concentration of about 18 mM.

[0503] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in 95 59768580.3Attorney Docket No.278925-561797 solution, wherein said iodide salt is KI, NaI, or NH4I, and wherein said iodide salt has a concentration of about 35 mM.

[0504] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, wherein said iodide salt is KI, and wherein said iodide salt has a concentration of about 35 mM.

[0505] In some embodiments, an herbicidal combination composition compriseshydrogen peroxide (H2O2) and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, further comprising a thiocyanate salt.

[0506] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, further comprising a thiocyanate salt.

[0507] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, and wherein said iodide salt is KI, NaI, or NH4I, further comprising a thiocyanate salt.

[0508] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, and wherein said iodide salt is KI, further comprising a thiocyanate salt.

[0509] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, wherein said iodide salt is KI, NaI, or NH4I, and wherein said iodide salt has a concentration of about 18 mM, further comprising a thiocyanate salt.

[0510] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, wherein said iodide salt is KI, and wherein said iodide salt has a concentration of about 18 mM, further comprising a thiocyanate salt. 96 59768580.3Attorney Docket No.278925-561797

[0511] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2 is dissolved in solution, wherein said iodide salt is KI, NaI, or NH4I, and wherein said iodide salt has a concentration of about 35 mM, further comprising a thiocyanate salt.

[0512] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant, wherein said H2O2is dissolved in solution, wherein said iodide salt is KI, and wherein said iodide salt has a concentration of about 35 mM, further comprising a thiocyanate salt.

[0513] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, or NH4SCN.

[0514] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN.

[0515] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, or NH4SCN, and wherein said thiocyanate salt has a concentration of about 4 mM or about 8 mM.

[0516] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN, and wherein said thiocyanate salt has a concentration of about 4 mM or about 8 mM.

[0517] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above 97 59768580.3Attorney Docket No.278925-561797 embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN, NaSCN, or NH4SCN, and wherein said thiocyanate salt has a concentration of about 80 mM.

[0518] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising a thiocyanate salt, wherein said thiocyanate salt is KSCN, and wherein said thiocyanate salt has a concentration of about 80 mM.

[0519] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising glucose at a concentration of about 100 mM to about 300 mM.

[0520] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising sodium acetate at a concentration of about 50 mM to 200 mM.

[0521] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, wherein said composition is at a pH of about 4.5 to about 5.5.

[0522] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising lactoperoxidase.

[0523] In some embodiments, an herbicidal combination composition comprisesH2O2 and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising lactoperoxidase, wherein said lactoperoxidase is at a concentration of about 25 U / mL to about 50 U / mL.

[0524] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising glucose oxidase. 98 59768580.3Attorney Docket No.278925-561797

[0525] In some embodiments, an herbicidal combination composition comprisesH2O2and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant as described in any of the above embodiments, further comprising glucose oxidase, wherein said glucose oxidase is at a concentration of about 20 U / mL to about 40 U / mL.

[0526] The herbicides or herbicide enhancers may comprise iodo, hypo-, and inter-pseudo-halogen species that are oxidative products may be biocatalytically generated. In some embodiments they are generated from thiocyanate and iodide. In other embodiments they are generated by two enzymes: glucose oxidase (GOx) and lactoperoxidase (LP). GOx generates hydrogen peroxide (H2O2) from D-glucose and oxygen, while LP catalyzes the oxidation of thiocyanate and iodide ions with H2O2 to transiently produce hypothiocyanite (OSCN-) and hypoiodite (OI-). These are subsequently converted to a mixture of oxidative species including iodine (I2), triiodide (I3-) and interspecies such as I2SCN- and I(SCN)2-.

[0527] The disclosure contemplates incorporating the herbicidal combinationcompositions disclosed herein into multiple types of products. By way of example, the herbicidal combination compositions may be comprised within one or more powders that are reconstituted with water to the working concentration. In additional embodiments, the powder comprises one or more enzyme concentrates or the enzymes are added prior to or at the time of use. Additionally, the disclosure contemplates an aqueous pre-concentrate that is diluted with water to the working concentration. In additional embodiments, the aqueous pre- concentrate comprises one or more enzyme concentrates or the enzymes are added prior to or at the time of use. As another example, the disclosure contemplates a liquid concentrate with the herbicidal components, including enzymatic herbicidal products, already produced and contained within the liquid concentrate. The concentrate is diluted with water prior to or at the time of use.

[0528] The composition can be applied by means of coating, spraying, sprinkling,atomizing, overhead spraying, watering, immersing, overhead irrigation, and drip irrigation. A particularly advantageous method for applying the composition is spraying both by means of low volume methods (mist systems) and high-volume methods. Drip irrigation can be used for culture systems on rockwool and other growth substrates. The enzyme systems according to the disclosure can also be used to disinfect drip irrigation systems. In both latter cases the presence of the oil base is not strictly necessary for an optimal activity. Immersion in a bath 99 59768580.3Attorney Docket No.278925-561797 with the composition is particularly suitable
for the treatment of plant parts, in particular harvestable parts, such as bulbs, tubers, fruits and the like.

[0529] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L- glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0530] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L- configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0531] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from 100 59768580.3Attorney Docket No.278925-561797 about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0532] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L- configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0533] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt, e.g., KI, NaI, NH4I, or combinations thereof; a thiocyanate salt, e.g., KSCN, NaSCN, NH4SCN, or combinations thereof; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) 101 59768580.3Attorney Docket No.278925-561797 and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0534] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI, NaI, NH4I, or combinations thereof in an amount ranging from about 0.01 mM to about 10 mM, KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 1 mM to about 100 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L- glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0535] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI, NaI, NH4I, or combinations thereof in an amount ranging from about 0.1 mM to about 5 mM, KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM to about 80 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L- glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- 102 59768580.3Attorney Docket No.278925-561797 dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0536] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI, NaI, NH4I, or combinations thereof in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN, NaSCN, NH4SCN, or combinations thereof in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2- methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0537] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI, a thiocyanate salt, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2- 103 59768580.3Attorney Docket No.278925-561797 methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0538] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an KI in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0539] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein 104 59768580.3Attorney Docket No.278925-561797 (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0540] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising KI in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0541] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt, KSCN, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2- methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0542] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from 105 59768580.3Attorney Docket No.278925-561797 about 0.01 mM to about 10 mM, KSCN in an amount ranging from about 1 mM to about 100 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0543] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.1 mM to about 5 mM, KSCN in an amount ranging from about 5 mM to about 80 mM, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0544] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; KSCN in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its 106 59768580.3Attorney Docket No.278925-561797 salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0545] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L- configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0546] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L- glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, 107 59768580.3Attorney Docket No.278925-561797 oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0547] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L- glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0548] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount of about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, or about 5 mM; a thiocyanate salt in an amount ranging from about 5 mM, about 10 mM, about 15 mM, about 20 mM, about 40 mM, about or about 80 mM; a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L- glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, 108 59768580.3Attorney Docket No.278925-561797 dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0549] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L-glufosinate (L- configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0550] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.01 mM to about 10 mM, a thiocyanate salt in an amount ranging from about 1 mM to about 100 mM, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof, selected from glufosinate, glufosinate-ammonium, L- glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, 109 59768580.3Attorney Docket No.278925-561797 bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, or any combination thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio, as defined by the Colby Formula.

[0551] In some embodiments, a herbicidal combination composition comprises: (A)an herbicide enhancer composition comprising an iodide salt in an amount ranging from about 0.1 mM to about 5 mM, a thiocyanate salt in an amount ranging from about 5 mM to about 80 mM, a sugar, such as a monosaccharide or disaccharide, e.g., glucose, fructose, galactose, sucrose, or combinations thereof, and (B) one or more chem...

Claims

Attorney Docket No.278925-561797 CLAIMS What is claimed is:

1. A herbicide enhancer composition comprising an iodide salt and a thiocyanate salt.

2. The composition of claim 1, wherein said iodide salt is KI, NaI, NH4I, or combinations thereof.

3. The composition of claim 2, wherein said iodide salt is KI.

4. The composition of any one of claims 2-3, wherein said iodide salt has a concentration ranging from about 0.1 mM to about 10 mM.

5. The composition of any one of claims 2-4, wherein said iodide salt has a concentration of about 0.1 mM, about 0.5 mM, about 1 mM, about 2 mM, about 2.5 mM, about 5 mM, about 6 mM, about 7 mM, about 8 mM, about 9 mM, or about 10 mM.

6. The composition of any one of claims 1-5, wherein said thiocyanate salt is KSCN, NaSCN, NH4SCN, or combinations thereof.

7. The composition of claim 6, wherein said thiocyanate salt is KSCN.

8. The composition of any one of claims 6-7, wherein said thiocyanate salt has a concentration ranging from between about 1 mM to about 80 mM.

9. The composition of claim 8, wherein said thiocyanate salt has a concentration ranging from between: about 5 mM to about 40 mM, about 10 mM to about 60 mM, about 20 mM to about 40 mM, about 40 mM to about 80 mM, or between about 20 mM and about 80 mM.

10. The composition of claim 9, wherein said thiocyanate salt has a concentration of about 15 mM, about 20 mM, about 25 mM, about 30 mM, about 40 mM, about 50 mM, about 60 mM, about 70 mM, or about 80 mM.

11. The composition of any one of claims 1-10, further comprising a pH buffer. 335 59768580.3Attorney Docket No.278925-561797 12. The composition of claim 11, wherein said pH buffer is a phosphate buffer, an acetate buffer, a carboxylic acid buffer, an amine-based buffer, or an amino acid-based buffer.

13. The composition of claim 12, wherein said buffer has a phosphate salt concentration ranging between about 1 mM to about 50 mM.

14. The composition of claim 13, wherein the phosphate salt comprises NaH2PO4.

15. The composition of any one of claims 1-14, further comprising a sugar.

16. The composition of claim 15, wherein the sugar is a monosaccharide or disaccharide selected from the group consisting of: glucose, fructose, galactose, and sucrose.

17. The composition of any one of claims 16, wherein said monosaccharide has a concentration ranging from: about 1 mM to about 200 mM, from about 1 mM to about 10 mM, or from about 5 mM to about 50 mM.

18. The composition of any one of claims 1-17, further comprising a hydrogen peroxide producing enzyme.

19. The composition of claim 18, wherein the hydrogen peroxide producing enzyme is at a concentration of about 0.1 U / mL to about 50 U / mL, about 1 U / mL to about 10 U / mL, about 10 U / mL to about 20 U / mL, about 20 U / mL to about 30 U / mL, about 30 U / mL to about 40 U / mL, or about 40 U / mL to about 50 U / mL.

20. The composition of claim 19, wherein the hydrogen peroxide producing enzyme is at a concentration of about 5 U / mL, about 10 U / mL, or about 20 U / mL.

21. The composition of any one of claims 18-20, wherein the hydrogen peroxide producing enzyme is an oxidase, e.g., a glucose oxidase.

22. The composition of any one of claims 1-17, further comprising hydrogen peroxide (H2O2). 336 59768580.3Attorney Docket No.278925-561797 23. The composition of claim 22, wherein the composition has a concentration of H2O2ranging from about 0.001 mM to about 50 mM.

24. The composition of any one of claims 1-23, further comprising a free radical producing (FRP) enzyme operable to catalyze hydrogen peroxide, iodide, and thiocyanate.

25. The composition of claim 24, wherein the free radical producing (FRP) enzyme is a peroxidase.

26. The composition of claim 25, wherein the peroxidase has a concentration ranging from about 0.5 U / mL to about 50 U / mL.

27. The composition of claim 26, wherein the peroxidase has a concentration ranging from about 0.3 U / mL to about 3 U / mL, about 1 U / mL to about 5 U / mL, about 5 U / mL to about 10 U / mL, about 10 U / mL to about 15 U / mL, about 15 U / mL to about 20 U / mL, about 20 U / mL to about 25 U / mL, or about 12 U / mL to about 25 U / mL.

28. The composition of claim 25, wherein the peroxidase has a concentration of about 1 U / mL, about 3 U / mL, about 12 U / mL or about 25 U / mL.

29. The composition of any one of claims 25-28, wherein the peroxidase is lactoperoxidase.

30. The composition of any one of claims 1-29, wherein said composition has a pH of about 4.0, about 5.0, about 6.0, about 7.0, about 8.0, about 5.0 to about 8.0, or about 6.0 to about 7.0, and all values inclusive of, and between pH of about 4.0 and about 8.

0.

31. A herbicidal combination composition comprising: (A) an herbicide enhancer composition of any one of claims 1-30, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are each independently present in the herbicidal combination composition in an amount which when applied to a plant or locus thereof, results in a greater than additive herbicidal effect. 337 59768580.3Attorney Docket No.278925-561797 32. The composition of claim 31, wherein said chemical herbicide is Glufosinate, Glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L-glufosinate free acid, Glyphosate, Flumioxizan, Paraquat, Sufentrazone, Carfentrazone, Dicamba, Dimethylamine Salt of Dicamba, 2,4-Dichlorophenoxyacetic acid, Triclopyr, Imazapyr, Oxyfluorfen, Diquat, Tralkoxydim, Fluazifop-B-Butyl, Atrazine, Nicosulfuron, Rimsulfuron, Bentazon, Ammonium nonanoate, Ammonium salt of imazamox, Cumyluron, Diflufenican, Dimethylamine Salt of 2,4-D, Dimethylamine Salt of MCPA (2- methyl-4-chlorophenoxyacetic acid), Epyrifenacil, Ethofumesate, Halosulfuron-methyl, Imazethapyr-ammonium, Mesotrione, Metamitron, Metsulfuron-methyl, Pyraclonil, Quinclorac, Saflufenacil, Sulfentrazone, Trifludimoxazin, imazapyr aminocyclopyrachlor, metsulfuron, triclopyr amine, capric acids, caprylic acids, or any combination thereof.

33. The composition of claim 32, wherein said chemical herbicide is glufosinate, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, or combinations thereof.

34. The composition of claim 30 or 31, wherein said iodide salt is about 2 mM KI and said thiocyanate salt is about 40 mM KSCN.

35. The composition of claim 30 or 31, wherein said iodide salt is about 2.5 mM KI and said thiocyanate salt is about 40 mM KSCN.

36. The composition of claim 30 or 31, wherein said iodide salt is about 5 mM KI and said thiocyanate salt is about 80 mM KSCN.

37. The composition of claim 30 or 31, wherein said iodide salt is about 1 mM KI and said thiocyanate salt is about 20 mM KSCN.

38. The composition of claim 30 or 31, wherein said iodide salt is about 0.5 mM KI and said thiocyanate salt is about 15 mM KSCN. 338 59768580.3Attorney Docket No.278925-561797 39. The composition of claim 30 or 31, wherein said iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

40. The composition of claim 30 or 31, wherein said iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 20 U / mL glucose oxidase, and about 25 U / mL lactoperoxidase.

41. The composition of claim 30 or 31, wherein said iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

42. The composition of claim 30 or 31, wherein said iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 5 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

43. The composition of claim 30 or 31, wherein said iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, and about 10 mM phosphate.

44. The composition of claim 30 or 31, wherein said iodide salt is about 1.0 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, and about 30 mM phosphate.

45. The composition of claim 30 or 31, wherein said iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, and about 30 mM phosphate.

46. The composition of claim 30 or 31, wherein the iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase. 339 59768580.3Attorney Docket No.278925-561797 47. The composition of claim 30 or 31, wherein the iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 20 U / mL glucose oxidase, and about 25 U / mL lactoperoxidase.

48. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

49. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN.

50. The composition of claim 30 or 31, wherein the iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 5 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

51. The composition of claim 30 or 31, wherein the iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, and about 10 mM phosphate.

52. The composition of claim 30 or 31, wherein thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, and about 10 mM phosphate.

53. The composition of claim 30 or 31, wherein thiocyanate salt is about 80 mM KSCN, further comprising about 50 mM glucose, and about 10 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

54. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

55. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase. 340 59768580.3Attorney Docket No.278925-561797 56. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 6 mM glucose, about 20 mM phosphate, about 10 U / mL glucose oxidase, and about 12 U / mL lactoperoxidase.

57. The composition of claim 30 or 31, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

58. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

59. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

60. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 4 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

61. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 4 U / mL glucose oxidase.

62. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase.

63. The composition of claim 30 or 31, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase. 341 59768580.3Attorney Docket No.278925-561797 64. The composition of claim 30 or 31, wherein the iodide salt is about 1 mM KI, said thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase.

65. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase.

66. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

67. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, about 30 mM phosphate, about 5 U / mL glucose oxidase.

68. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 10 mM glucose, about 40 mM fructose, and about 30 mM phosphate.

69. The composition of claim 30 or 31, wherein thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM glucose, and about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

70. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, further comprising about 50 mM glucose, and about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

71. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM fructose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase. 342 59768580.3Attorney Docket No.278925-561797 72. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, said thiocyanate salt is about 15 mM KSCN, further comprising about 50 mM fructose, and about 30 mM phosphate.

73. The composition of claim 30 or 31, wherein the iodide salt is about 1 mM KI, the thiocyanate salt is about 20 mM KSCN, further comprising about 50 mM glucose, about 20 mM phosphate, about 5 U / mL F, and about 3 U / mL lactoperoxidase.

74. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

75. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 20 mM glucose, about 20 mM fructose, about 30 mM phosphate, and about 5 U / mL glucose oxidase.

76. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 20 mM glucose, about 20 mM sucrose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

77. The composition of claim 30 or 31, wherein the iodide salt is about 0.25 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 30 mM glucose, about 30 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

78. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

79. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 35 mM glucose, about 5 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase. 343 59768580.3Attorney Docket No.278925-561797 80. The composition of claim 30 or 31, wherein the iodide salt is about 2 mM KI, the thiocyanate salt is about 40 mM KSCN, further comprising about 20 mM glucose, about 20 mM phosphate, about 5 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

81. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, and about 6.0 U / mL glucose oxidase.

82. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 10 mM KSCN, further comprising about 35 mM glucose, about 5 mM phosphate, and about 6.0 U / mL glucose oxidase.

83. The composition of claim 30 or 31, wherein the iodide salt is about 0.5 mM KI, the thiocyanate salt is about 15 mM KSCN, further comprising about 40 mM glucose, about 15 mM phosphate, and about 6.0 U / mL glucose oxidase.

84. The composition of claim 30 or 31, wherein the iodide salt is about 0.1 mM KI, the thiocyanate salt is about 5 mM KSCN, further comprising about 50 mM glucose, and about 30 mM phosphate, about 6.0 U / mL glucose oxidase, and about 3 U / mL lactoperoxidase.

85. The composition of claim 31, further comprising an adjuvant, excipient, diluent or carrier selected from: water, toluene, xylene, petroleum ether, vegetable oils, acetone, methyl ethyl ketone, cyclohexanone, acid anhydrides, acetonitrile, acetophenone, amyl acetate, 2- butanone, buty lene carbonate, chlorobenzene, cyclohexane, cyclohexanol, alkyl esters of acetic acid, diacetone alcohol, 1,2-dichloro propane, diethanolamine, p-diethylbenzene, diethylene glycol, diethylene glycol abietate, diethylene glycol butyl ether, diethylene glycol ethyl ether, diethylene glycol methyl ether, N,N-dimethylformamide, dimethyl sulfoxide, 1,4- dioxane, dipropylene glycol, dipropylene glycol methyl ether, dipropylene glycol dibenzoate, diproxitol, alkylpyrrolidone, ethyl acetate, 2-ethylhexanol, ethylene carbonate, 1,1,1- trichloroethane, 2-heptanone, alpha-pinene, d-limonene, ethyl lactate, ethylene glycol, ethylene glycol butyl ether, ethylene glycol methyl ether, ganima-butyrolactone, glycerol, glycerol acetate, glycerol diacetate, glycerol triacetate, hexade cane, hexylene glycol, isoamyl acetate, isobornyl acetate, isooctane, isophorone, isopropylbenzene, isopropyl myristate, lactic acid, laurylamine, mesityl oxide, methoxy propanol, methyl isoamyl ketone, methyl 344 59768580.3Attorney Docket No.278925-561797 isobutyl ketone, methyl laurate, methyl octanoate, methyl oleate, methylene chloride, m- xylene, n-hexane, n-octylamine, octadecanoic acid, octylamine acetate, oleic acid, oleylamine, a-xylene, phenol, polyethylene glycol, propionic acid, propyl lactate, propylene carbonate, propylene glycol, propylene glycol methyl ether, p-xylene, toluene, triethyl phosphate, triethylene glycol, xylenesulfonic acid, paraffin, mineral oil, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, propylene glycol methyl ether, diethylene glycol methyl ether, methanol, ethanol, isopropanol, and alcohols of higher molecular weight, such as amyl alcohol, tetrahydrofurfuryl alcohol, hexanol, octanol, ethylene glycol, propylene glycol, glycerol, N-methyl-2-pyrrolidone, talc, titanium dioxide, pyrophyllite clay, silica, attapulgite clay, kieselguhr, limestone, calcium carbonate, bentonite, calcium montmorillonite, cottonseed husks, wheat flour, soybean flour, pumice, wood flour, ground walnut shells, lignin, salts of alkyl sulfates, such as diethanolanimonium lauryl sulfate; salts of alkylarylsulfonates, such as calcium dodecylbenzenesulfonate; alkylphenol / alkylene oxide addition products, such as nonylphenol ethoxylate; alcohol / alkylene oxide addition products, such as tridecylalcohol ethoxylate; soaps, such as sodium stearate, salts of alkylnaphthalenesulfonates, such as sodium dibutylnaphthalenesulfonate; dialkyl esters of sulfosuccinate salts, such as sodium di(2- ethylhexyl)sulfosuccinate; sorbitol esters, such as sorbitol oleate; quaternary amines, such as lauryltrimethylammonium chloride, polyethyleneglycol esters of fatty acids, such as polyethylene glycol stearate; block copolymers of ethylene oxide and propylene oxide; and salts of mono and di-alkylphosphate esters and combinations thereof.

86. A method of enhancing the efficacy of a chemical herbicide, or an agriculturally acceptable salt thereof, in a plant field, comprising the step of administering one or more chemical herbicides, or an agriculturally acceptable salt thereof, with a herbicide enhancer composition of any one of claims 1-30, to a target plant in said plant field; and wherein said enhancer composition increases the translocation of said one or more chemical herbicides, or an agriculturally acceptable salt thereof, within said target plant; and wherein said herbicide enhancer composition alone has between about 0% and about 5%, or preferably between about 0% and about 1%, or 0% herbicide activity when compared to the combination of said one or more chemical herbicides, or an agriculturally acceptable salt thereof and said herbicide enhancer composition. 345 59768580.3Attorney Docket No.278925-561797 87. The method of claim 86, wherein the combination of herbicide enhancer composition with the one or more herbicides results in the enhancement of the one or more chemical herbicides and their combined herbicidal activity is more than additive as determined using the Colby Formula.

88. The method of claim 86, wherein said enhancer comprises between about 0.5 and about 5 mM of said iodide salt, between about 15 and about 80 mM of said thiocyanate salt, between about 6 and about 100 mM of a monosaccharide component that comprises glucose and / or fructose, between about 5 and about 30 mM NaH2PO4, and between about 5 and about 20 U / mL glucose oxidase.

89. The method of claim 88, wherein the enhancer further comprises between about 3 and about 25 U / mL lactoperoxidase.

90. The method of claim 88, wherein said iodide salt is about 1 mM KI and said thiocyanate salt is about 20 mM KSCN.

91. The method of claim 88, wherein said iodide salt is about 0.5 mM KI and said thiocyanate salt is about 15 mM KSCN.

92. The method of claim 91, wherein said iodide salt is about 2.0 mM KI and said thiocyanate salt is about 40 mM KSCN.

93. The method of any one of claims 86-92, wherein said chemical herbicide comprises Glufosinate, Glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L- glufosinate ammonium, L-glufosinate free acid, Glyphosate, Flumioxizan, Paraquat, Sufentrazone, Carfentrazone, Dicamba, Dimethylamine Salt of Dicamba, 2,4- Dichlorophenoxyacetic acid, Triclopyr, Imazapyr, Oxyfluorfen, Diquat, Tralkoxydim, Fluazifop-B-Butyl, Atrazine, Nicosulfuron, Rimsulfuron, Bentazon, Ammonium nonanoate, Ammonium salt of imazamox, Cumyluron, Diflufenican, Dimethylamine Salt of 2,4-D, Dimethylamine Salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), Epyrifenacil, Ethofumesate, Halosulfuron-methyl, Imazethapyr-ammonium, Mesotrione, Metamitron, Metsulfuron-methyl, Pyraclonil, Quinclorac, Saflufenacil, Sulfentrazone, Trifludimoxazin, 346 59768580.3Attorney Docket No.278925-561797 Imazapyr Aminocyclopyrachlor, Metsulfuron,Triclopyr amine, Capric acids, caprylic acids, or any combination thereof.

94. The method of any one of claims 86-93, wherein said chemical herbicide and said enhancer composition are administered in a single composition, or sequentially in separate compositions.

95. The method of any one of claims 86-94, wherein said plant field is a crop field.

96. The method of claim 95, wherein said crop field comprises a crop that is not the target plant, wherein said crop is resistant to one or more herbicides.

97. The method of claim 96, wherein said herbicide is administered over the top of said crop and target plant.

98. The method of either one of claims 96 or 97, wherein said herbicide is glufosinate, 2,4-D choline, or a combination thereof.

99. The method of any one of claims 86-98, wherein said target plant is not on a farm.

100. The method of claim 99, wherein said target plant is on residential land, commercial land, within a forest, beside a road, or beside a utility structure.

101. A method of controlling unwanted plant growth comprising: applying a herbicidally effective amount of a herbicidal combination composition of any one of claims 28-82, or agrochemically acceptable salts thereof, to an unwanted plant or to the locus thereof.

102. The method of claim 101, wherein said herbicidal combination composition is administered by coating, spraying, sprinkling, atomizing, overhead spraying, watering, immersing, overhead irrigation, or drip irrigation.

103. The method of either one of claims 101 or 102, wherein said herbicidal combination compositions are administered to a whole plant or any part thereon. 347 59768580.3Attorney Docket No.278925-561797 104. The method of either one of claims 101 or 102, wherein said herbicidal combination compositions are administered to leaves on a plant.

105. The method of either one of claims 103 or 104, wherein said plant is a monocot or a dicot.

106. The method of either one of claims 103 or 104, wherein said plant is a broadleaf weed, nutsedge, grass weed, pigweed, velvetleaf, ragweed, or clover.

107. The method of claim 106, wherein said grass weeds are crabgrass or signalgrass.

108. A method of manufacturing an enzyme-free enhanced herbicidal combination composition, comprising: a) immobilizing an H2O2-producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b) exposing said immobilized H2O2-producing and free radical producing (FRP) enzymes to a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2-producing enzyme; c) collecting a product solution, wherein said product solution comprises reactive oxidative species; and d) combining said product solution with a chemical herbicide.

109. The method of claim 108, wherein said H2O2-producing enzyme is glucose oxidase (GOx) and said substrate is glucose.

110. The method of either one of claims 108 or 109, wherein said FRP enzyme is lactoperoxidase.

111. The method of any one of claims 108-109, wherein said iodide salt is KI.

112. The method of any one of claims 108-111, wherein said thiocyanate salt is KSCN.

113. The method of claim 108, wherein said chemical herbicide is glufosinate, glufosinate- ammonium, L-glufosinate (L-configuration) and / or its salts, L-glufosinate ammonium, L- 348 59768580.3Attorney Docket No.278925-561797 glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4-dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop-b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4- chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron-methyl, imazethapyr- ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, imazapyr aminocyclopyrachlor, metsulfuron, triclopyr amine, capric acids, caprylic acids, or any combination thereof.

114. The method of claim 113, wherein said chemical herbicide is glufosinate.

115. The method of claim 108, said iodide salt is about 2 mM KI and said thiocyanate salt is about 40 mM KSCN.

116. The method of claim 108, said iodide salt is about 2.5 mM KI and said thiocyanate salt is about 40 mM KSCN.

117. The method of claim 108, said iodide salt is about 5 mM KI and said thiocyanate salt is about 80 mM KSCN.

118. The method of claim 113, wherein said iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, wherein said substrate for said H2O2-producing enzyme is about 50 mM glucose and 10 U / mL glucose oxidase, further comprising about 10 mM phosphate, and wherein said lactoperoxidase is at about 12 U / mL.

119. The method of claim 113, wherein said iodide salt is about 5 mM KI, said thiocyanate salt is about 80 mM KSCN, wherein said substrate for said H2O2-producing enzyme is about 50 mM glucose and 20 U / mL glucose oxidase, further comprising about 10 mM phosphate, and wherein said lactoperoxidase is at about 25 U / mL.

120. The method of claim 113, wherein said iodide salt is about 2 mM KI, said thiocyanate salt is about 40 mM KSCN, wherein said substrate for said H2O2-producing enzyme is about 349 59768580.3Attorney Docket No.278925-561797 50 mM glucose and 10 U / mL glucose oxidase, further comprising about 10 mM phosphate, and wherein said lactoperoxidase is at about 12 U / mL.

121. The method of claim 113, wherein said iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, wherein said substrate for said H2O2-producing enzyme is about 50 mM glucose and 10 U / mL glucose oxidase, further comprising about 5 mM phosphate, and wherein said lactoperoxidase is at about 12 U / mL.

122. The method of claim 113, wherein said iodide salt is about 2.5 mM KI, said thiocyanate salt is about 40 mM KSCN, further comprising about 50 mM glucose and about 10 mM phosphate.

123. A composition, comprising hydrogen peroxide and an iodide salt, wherein said composition is optimized to be a broad-spectrum and non-selective herbicide, defoliant, or plant desiccant.

124. The composition of claim 119, wherein said hydrogen peroxide is dissolved the solution.

125. The composition of claim 124, wherein said iodide salt is KI, NaI, or NH4I.

126. The composition of claim 125, wherein said iodide salt is KI.

127. The composition of any one of claims 125-126, wherein said iodide salt has a concentration of about 18 mM.

128. The composition of any one of claims 125-126, wherein said iodide salt has a concentration of about 35 mM.

129. The composition of any one of claims 123-128, further comprising a thiocyanate salt.

130. The composition of claim 129, wherein said thiocyanate salt is KSCN, NaSCN, or NH4SCN. 350 59768580.3Attorney Docket No.278925-561797 131. The composition of claim 130, wherein said thiocyanate salt is KSCN.

132. The composition of any one of claims 129-131, wherein said thiocyanate salt has a concentration of about 4 mM or about 8mM.

133. The composition of any one of claims 129-132, wherein said thiocyanate salt has a concentration of about 80 mM.

134. The composition of any one of claims 123-133, wherein said composition further comprises glucose at a concentration of about 100 mM to about 300 mM.

135. The composition of any one of claims 123-134, wherein said composition further comprising sodium acetate at a concentration of about 50 to 200 mM.

136. The composition of any one of claims 123-135, wherein said composition is at a pH of about 4.5 to about 5.

5.

137. The composition of any one of claims 123-136, further comprising lactoperoxidase.

138. The composition of claim 137, wherein said lactoperoxidase is at a concentration of about 25-50 U / mL.

139. The composition of any one of claims 123-138, further comprising glucose oxidase.

140. The composition of claim 139, wherein said glucose oxidase is at a concentration of about 20-40 U / mL.

141. A method of desiccating a plant, the method comprising administering a herbicidally effective amount of a herbicidal combination composition to the plant or a locus thereof.

142. A method of controlling, inhibiting, or killing a weed, the method comprising administering a herbicidally effective amount of a herbicidal combination composition to the weed or a locus thereof. 351 59768580.3Attorney Docket No.278925-561797 143. A method of controlling, inhibiting, or killing a weed in a land area used for cultivating a crop, the method comprising: administering a herbicidal combination composition comprising: (A) an herbicide enhancer composition, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio; and wherein the crop has a herbicide insensitivity to the one or more herbicides.

144. The method of claim 143, wherein the crop has a natural herbicide insensitivity to the one or more chemical herbicides, or has been genetically engineered to have an increased herbicide insensitivity to one or more herbicides relative to a wild-type crop.

145. A method for controlling or killing a plant that is insensitive to a chemical herbicide, the method comprising administering a herbicidally effective amount of a herbicidal combination composition to the plant or a locus thereof, wherein the herbicide present in the herbicidal combination composition comprises the same herbicide the treated plant displays said insensitivity to.

146. The method of claim 145, wherein the herbicide insensitivity is glyphosate insensitivity.

147. The method of claim 145, wherein the herbicide insensitivity is glufosinate insensitivity.

148. The method of claim 145, wherein the herbicide insensitivity is 2,4-D insensitivity.

149. The method of claim 145, wherein the herbicide insensitivity is Dicamba insensitivity.

150. The method of any one of claims 142-144, wherein the weed is a monocotyledonous weed or a dicotyledonous weed.

151. The method of any one of claims 142-144, wherein the weed is a broadleaf or grass.

152. The method of any one of claims 142-144, wherein the weed is selected from the group consisting of: Amaranthus viridis, Cenchrus echinatus, broadleaf signalgrass 352 59768580.3Attorney Docket No.278925-561797 (Brachiaria platyphylla), large crabgrass (Digitaria sanguinalis), barnyard grass (Echinochloa crus-galli), rigid ryegrass (Lolium rigidum), fall panicum (Panicum dichotomiflorum), giant foxtail (Setaria faberi), green foxtail (Setaria viridis), Johnsongrass (Sorghum halepense), velvetleaf (Abutilon theophrasti), redroot pigweed (Amaranthus retroflexus), common lambsquarters (Chenopodium album), ivyleaf morning glory (Ipomoea hederacea), common purslane (Portulaca oleracea), and common cocklebur (Xanthium strumarium); Alopecurus myosuroides Huds. (blackgrass, ALOMY), Alternanthera tenella (ALRTE), Amaranthus hybridus (AMAHH), Amaranthus palmeri (Palmer amaranth, AMAPA), Amaranthus retroflexus (redroot pigweed, AMARE), Amaranthus viridis (slender amaranth, AMAVI), Avena fatua (wild oat, AVEFA), Avena sativa (common oat, AVESA), Bidens subalternans (greater beggarticks, BIDSU), Brachiaria decumbens Stapf. or Urochloa decumbens (Stapf), Brachiaria brizantha or Urochloa brizantha, Brachiaria platyphylla (Groseb.) Nash or Urochloa platyphylla (broadleaf signalgrass, BRAPP), Brachiaria plantaginea or Urochloa plantaginea (alexandergrass, BRAPL), Cenchrus echinatus (southern sandbur, CENEC), Chloris polydactyla (CHRPO), Digitaria horizontalis Willd. (Jamaican crabgrass, DIGHO), Digitaria insularis (sourgrass, TRCIN), Digitaria nuda (DIGNU), Digitaria sanguinalis (large crabgrass, DIGSA), Echinochloa crus-galli (barnyardgrass, ECHCG), Echinochloa colonum (junglerice, ECHCO), Eleusine indica Gaertn. (goosegrass, ELEIN), Lolium multiflorum Lam. (Italian ryegrass, LOLMU), Panicum dichotomiflorum Michx. (fall panicum, PANDI), Panicum miliaceum L. (wild-proso millet, PANMI), Sesbania exaltata (hemp sesbania, SEBEX), Setaria faberi Herrm. (giant foxtail, SETFA), Setaria viridis (green foxtail, SETVI), Sorghum halepense (Johnsongrass, SORHA), Sorghum bicolor Moench ssp. arundinaceum (shattercane, SORVU), Cyperus esculentus (yellow nutsedge, CYPES), Cyperus rotundus (purple nutsedge, CYPRO), Abutilon theophrasti (velvetleaf, ABUTH), Amaranthus species (pigweeds and amaranths, AMASS), Ambrosia artemisiifolia L. (common ragweed, AMBEL), Ambrosia psilostachya DC. (western ragweed, AMBPS), Ambrosia trifida (giant ragweed, AMBTR), Anoda cristata (spurred anoda, ANVCR), Asclepias syriaca (common milkweed, ASCSY), Bidens pilosa (hairy beggarticks, BIDPI), Borreria species (BOISS), Borreria alata or Spermacoce alata Aubl. or Spermacoce latifolia (broadleaf buttonweed, BOILF), Chenopodium album L. (common lambsquarters, CHEAL), Cirsium arvense (Canada thistle, CIRAR), Commelina benghalensis (tropical spiderwort, COMBE), Datura stramonium (jimsonweed, DATST), Daucus carota (wild carrot, DAUCA), Euphorbia heterophylla (wild poinsettia, EPHHL), Euphorbia hirta or Chamaesyce hirta (garden spurge, EPHHI), Euphorbia dentata Michx. 353 59768580.3Attorney Docket No.278925-561797 (toothed spurge, EPHDE), Erigeron bonariensis or Conyza bonariensis (hairy fleabane, ERIBO), Erigeron canadensis or Conyza canadensis (horseweed, ERICA), Conyza sumatrensis (tall fleabane, ERIFL), Helianthus annuus (common sunflower, HELAN), Jacquemontia tamnifolia (smallflower morningglory, IAQTA), Ipomoea hederacea (ivyleaf morningglory, IPOHE), Ipomoea lacunosa (white morningglory, IPOLA), Lactuca serriola (prickly lettuce, LACSE), Portulaca oleracea (common purslane, POROL), Richardia species (pusley, RCHSS), Salsola tragus (Russian thistle, SASKR), Sida species (sida, SIDSS), Sida spinosa (prickly sida, SIDSP), Sinapis arvensis (wild mustard, SINAR), Solanum ptychanthum (eastern black nightshade, SOLPT), Tridax procumbens (coat buttons, TRQPR), Rumex dentatus (RUMDE) or Xanthium strumarium (common cocklebur, XANST), and Ricinus communis (castorbean, RIICO).

153. The method of any one of claims 142-144, wherein the weed is selected from a weed belonging to the genera: Cassia, Erigeron, Sinapis, Lepidium, Galium, Stellaria, Matricaria, Geranium, Anthemis, Galinsoga, Chenopodium, Urtica, Senecio, Amaranthus, Erodium, Portulaca, Xanthium, Convolvulus, Ipomoea, Polygonum, Malva, Sesbania, Ambrosia, Cirsium, Carduus, Sonchus, Anagallis, Solanum, Rorippa, Rotala, Lindernia, Lamium, Veronica, Oxalis, Abutilon, Emex, Datura, Viola, Galeopsis, Papaver, Centaurea, Trifolium, Ranunculus, Sphenoclea, Taraxacum, Plantago, Epilobium, Rubus, Achillea, Rumex, Lotus, Bellis, Echinochloa, Eriochloa, Setaria, Panicum, Digitaria, Phleum, Poa, Festuca, Eleusine, Brachiaria, Lolium, Bromus, Avena, Hordeum, Cyperus, Sorghum, Agropyron, Cynodon, Monochoria, Fimbristylis, Sagittaria, Eleocharis, Scirpus, Paspalum, Ischaemum, Dactyloctenium, Agrostis, Alopecurus, Apera, Aegilops, Phalaris, and Amaranthus spp.

154. A method of controlling, inhibiting, or killing a plant in a land area used for a right- of-way, the method comprising: administering a herbicidal combination composition comprising: (A) an herbicide enhancer composition, and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

155. The method of any one of claims 154, wherein the composition is administered to a residential land area; a commercial land area; a forest; a highway; a road; beside a road; beside a utility structure; an airport; a railroad; a railroad track; an area around an electric utility; a pipeline; a public surface drainage way; an irrigation waterway; a bank of a public 354 59768580.3Attorney Docket No.278925-561797 barge way; an area around a lock; an area around a dam; a bicycle trail; a bridle trail; a public path; a public trail; or an area outside an established recreational area.

156. The method of claim 155, wherein the composition is administered on residential land, commercial land, within a forest, beside a road, or beside a utility structure.

157. The method any one of claims 154-156, wherein the plant is Populus deltoides; Populus tremuloides; Salix nigra; Acer saccharinum; Pinus strobus; Pinus taeda; Quercus rubra; Quercus alba; Liquidambar styraciflua; Platanus occidentalis; Elaeagnus umbellata; Lonicera maackii; Lonicera morrowii; Lonicera tatarica; Rosa multiflora; Berberis thunbergii; Rhamnus cathartica; Frangula alnus; Cytisus scoparius; Ligustrum spp.; Pueraria montana var. lobata; Lonicera japonica; Celastrus orbiculatus; Hedera helix; Wisteria sinensis; Wisteria floribunda; Cirsium arvense; Cirsium vulgare; Heracleum mantegazzianum; Conium maculatum; Ambrosia artemisiifolia; Amaranthus spp.; Reynoutria japonica; Lythrum salicaria; Sorghum halepense; Imperata cylindrica; Cynodon dactylon; Phalaris arundinacea; Cortaderia selloana; Phragmites australis; Tamarix spp.; Acroptilon repens; Brassica tournefortii; Alhagi maurorum; Triadica sebifera; Solanum viarum; Lantana camara; Calopogonium mucunoides; Parthenium hysterophorus; Chromolaena odorata; Spathodea campanulata; Rubus moluccanus; Psidium cattleyanum; Clidemia hirta; Mikania micrantha; Hedychium gardnerianum; Pennisetum setaceum; Tradescantia fluminensis; Oxalis pes-caprae; Arundo donax; Berberis spp.; Ailanthus altissima; Alliaria petiolata; Euphorbia virgata; Carduus nutans; Onopordum acanthium; Hieracium spp.; Jacobaea vulgaris; Leucanthemum vulgare; Rubus armeniacus; Impatiens glandulifera; Clematis vitalba; Eichhornia crassipes; Ulex europaeus; or Echium plantagineum.

158. The method of any one of claims 141-158, wherein said composition is administered by coating, spraying, sprinkling, atomizing, overhead spraying, watering, immersing, overhead irrigation, or drip irrigation.

159. The method of claim 158, wherein said composition is administered by spraying.

160. The method of any one of claims 141-159, wherein said compositions are administered to weed or plant leaves. 355 59768580.3Attorney Docket No.278925-561797 161. The method of any one of claims 141-159, wherein said compositions are administered to whole weeds or plants.

162. A method of manufacturing an enzyme-free herbicidal combination composition, comprising: a. immobilizing an H2O2-producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b. exposing said immobilized H2O2-producing and free radical producing (FRP) enzymes to a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2-producing enzyme; and c. collecting a product solution, wherein said product solution comprises reactive oxidative species.

163. The method of claim 162, wherein said H2O2-producing enzyme is glucose oxidase (GOx) and said substrate is glucose.

164. The method of either one of claims 162-163, wherein said FRP enzyme is lactoperoxidase.

165. The method of any one of claims 162-164, wherein said iodide salt is KI.

166. The method of any one of claims 162-162, wherein said thiocyanate salt is KSCN.

167. The method of claim 163, wherein said glucose is at a concentration of about 100 mM or about 300 mM in said solution.

168. The method of any one of claims 162-165, wherein said KI is at a concentration ranging from about 0.1 mM to about 40 mM in said solution.

169. The method of any one of claims 162-165, wherein said KI is at a concentration of about 18 mM in said solution.

170. The method of any one of claims 159-166, wherein said KSCN is at a concentration ranging from about 1mM or about 80 mM in said solution. 356 59768580.3Attorney Docket No.278925-561797 171. The method of any one of claims 162-166, wherein said KSCN is at a concentration of about 5 mM, about 10 mM, about 20 mM, 40 mM, 60mM or about 80 mM in said solution.

172. The method of any one of claims 162-171, wherein said product solution comprises one or more reactive oxidative species selected from the group consisting of I2, I3-, I2SCN-, and I(SCN)2-.

173. The method of any one of claims 162-172, wherein said H2O2-producing enzyme and FRP enzyme are immobilized on hematite.

174. The method of any one of claims 162-173, wherein said reaction container is a packed bed reactor.

175. The method of claim 162, wherein said reaction solution is pumped with a high- pressure pump through said packed bed reactor.

176. A method of manufacturing an herbicidal combination composition, comprising: a. placing an H2O2-producing enzyme and a free radical producing (FRP) enzyme in a reaction container, b. exposing said H2O2-producing and free radical producing (FRP) enzymes to a reaction solution comprising an iodide salt, a thiocyanate salt, and a substrate for said H2O2- producing enzyme; and c. collecting a product solution, wherein said product solution comprises reactive oxidative species.

177. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

178. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a sugar; and (B) one or more 357 59768580.3Attorney Docket No.278925-561797 chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

179. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, monosaccharide or disaccharide selected from the group consisting of: glucose, fructose, galactose, and sucrose; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

180. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a monosaccharide; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

181. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a monosaccharide, and a pH buffer; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

182. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a monosaccharide, a pH buffer, and an oxidase, e.g., glucose oxidase; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

183. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a monosaccharide, a pH buffer, and a peroxidase, e.g., a lactoperoxidase; and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio. 358 59768580.3Attorney Docket No.278925-561797 184. A herbicidal combination composition comprising: (A) an herbicide enhancer composition comprising an iodide salt, a thiocyanate salt, a monosaccharide, a pH buffer, and hydrogen peroxide (H2O2); and (B) one or more chemical herbicides, or an agrochemically acceptable salt thereof; wherein (A) and (B) are present in the herbicidal combination composition in a greater than additive weight ratio.

185. The herbicidal combination composition of any one of claims 177 to 184, wherein the one or more chemical herbicides, or an agrochemically acceptable salt thereof, is selected from: glufosinate, glufosinate-ammonium, L-glufosinate (L-configuration) and / or its salts, L- glufosinate ammonium, L-glufosinate free acid, glyphosate, flumioxizan, paraquat, sufentrazone, carfentrazone, dicamba, dimethylamine salt of dicamba, 2,4- dichlorophenoxyacetic acid, triclopyr, imazapyr, oxyfluorfen, diquat, tralkoxydim, fluazifop- b-butyl, atrazine, nicosulfuron, rimsulfuron, bentazon, ammonium nonanoate, ammonium salt of imazamox, cumyluron, diflufenican, dimethylamine salt of 2,4-D, dimethylamine salt of MCPA (2-methyl-4-chlorophenoxyacetic acid), epyrifenacil, ethofumesate, halosulfuron- methyl, imazethapyr-ammonium, mesotrione, metamitron, metsulfuron-methyl, pyraclonil, quinclorac, saflufenacil, sulfentrazone, trifludimoxazin, imazapyr aminocyclopyrachlor, metsulfuron, triclopyr amine, capric acids, caprylic acids, or any combination thereof.

186. The herbicidal combination composition of any one of claims 177 to 184, wherein the one or more chemical herbicides, or an agrochemically acceptable salt thereof, is selected from: glufosinate, carfentrazone, flumioxazin, sulfentrazone, paraquat, 2,4- dichlorophenoxyacetic acid, glyphosate, triclopyr, dicamba, or any combination thereof.

187. The herbicidal combination composition of any one of claims 177 to 184, wherein the one or more chemical herbicides, or an agrochemically acceptable salt thereof, is glufosinate.

188. The herbicidal combination composition of any one of claims 177-187, wherein the greater than additive weight ratio is a ratio of components (A) to (B), ranging from about 1:1,000 to about 1,000:1, such that the two components in the composition leads to a herbicidal effect that is more than additive as determined using the Colby Formula. 359 59768580.3Attorney Docket No.278925-561797 189. The method of any one of claims 146-149, wherein the concentration of the one or more herbicides in the herbicidal combination composition includes a concentration of the one or more herbicides that the herbicide insensitive plant is tolerant to. 360 59768580.3

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