Stents for patients with osteoarthritis in different bone conditions

Abstract

The present invention discloses a support for patients with osteoarthritis of different bone conditions, comprising: a bottom support, a middle support and a porous polymer material layer; the top surface of the bottom support is fixedly connected to the bottom surface of the middle support, and the top surface of the middle support is fixedly connected to the bottom surface of the porous polymer material layer; the bottom support is arranged as a multi-layer structure, the bottom support is composed of a plurality of TC4 plates stacked together, a pore group is opened on the top surface of the TC4 plate, the pore groups of the plurality of TC4 plates are vertically connected, and the middle support is arranged as a titanium alloy 3D printing plate; the top surface of the titanium alloy 3D printing plate is provided with a plurality of connecting hole groups adapted to the pore group, the bottom openings of the connecting hole groups are connected to the pore groups of the plurality of TC4 plates, the top surface of the titanium alloy 3D printing plate is fixedly connected to the bottom surface of the porous polymer material layer, and the bottom of the porous polymer material layer closes the top opening of the connecting hole group.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a bracket for patients with osteoarthritis of different bone conditions. Background Art

[0002] Osteoarthritis is a common and frequent disease among the middle-aged and elderly population. It has become the number one cause of disability in the elderly and seriously affects the quality of life. Some current clinical treatments cannot provide good repair effects for large cartilage defects formed in the middle and late stages of osteoarthritis. Large cartilage defects can only be treated by joint replacement surgery. For middle-aged and elderly patients, due to factors such as height, weight and genetics, the mechanical properties of bone and cartilage are very different, and the elderly are often accompanied by osteoporosis. Tissue engineering is a concept of planting cells on a scaffold. This whole is cultured in a bioreactor, where appropriate stimulation (chemical, biological, mechanical and electrical) is applied to form new tissue in a relatively short period of time. This new tissue is then implanted into the body to help patients restore function. The scaffold is a three-dimensional template that provides a framework for cell growth. In the initial stage, cells are uniformly colonized on the scaffold to obtain ideal clinical results. Studies have found that scaffolds designed with high permeability, porosity and specific surface area can achieve very high cell seeding efficiency. Under the same macrostructure dimensions (same length, width, and height) and the same porosity, the specific surface area of ​​the truncated octahedron is three times that of the cubic structure, which not only exhibits better cell seeding efficiency but also good cell distribution in the scaffold. Summary of the invention

[0003] The purpose of the present invention is to provide a stent for patients with osteoarthritis of different bone conditions to solve the problems existing in the prior art.

[0004] To achieve the above-mentioned purpose, the present invention provides the following solutions: The present invention provides a stent for patients with osteoarthritis of different bone conditions, comprising: a bottom stent, a middle stent and a porous polymer material layer; the top surface of the bottom stent is fixedly connected to the bottom surface of the middle stent, and the top surface of the middle stent is fixedly connected to the bottom surface of the porous polymer material layer;

[0005] The bottom support is configured as a multi-layer structure, the bottom support is composed of a plurality of stacked TC4 plates, a pore group is provided on the top surface of the TC4 plate, the pore groups of the plurality of TC4 plates are vertically connected, and the middle support is configured as a titanium alloy 3D printing plate; a plurality of connecting pore groups adapted to the pore group are provided on the top surface of the titanium alloy 3D printing plate, the bottom openings of the connecting pore groups are connected to the pore groups of the plurality of TC4 plates, the top surface of the titanium alloy 3D printing plate is fixedly connected to the bottom surface of the porous polymer material layer, and the bottom of the porous polymer material layer closes the top opening of the connecting pore group.

[0006] Preferably, a plurality of mutually interwoven through holes are provided in the porous polymer material layer, and the apertures of the through holes gradually decrease from the outside to the inside.

[0007] Preferably, Chinese medicine powder is distributed in the porous polymer material layer.

[0008] Preferably, the pore group includes a first pore grouping, a second pore grouping and a third pore grouping; the first pore grouping is opened at the center of the top surface of the TC4 plate, a plurality of the second pore groups are opened outside the first pore grouping, a plurality of the second pore groups form a first rectangular structure on the top surface of the TC4 plate, the first pore grouping is located at the center of the first rectangular structure, a plurality of the third pore groups are opened outside the second pore grouping, a plurality of the third pore groups form a second rectangular structure on the top surface of the TC4 plate, and the first rectangular structure is located at the center of the second rectangular structure; the first pore grouping, the second pore grouping and the third pore grouping all have a plurality of pores, the first pore grouping, the second pore grouping and the third pore grouping occupy the same area, and the number of pores of the first pore grouping, the second pore grouping and the third pore grouping gradually decreases, and the pore diameter gradually increases, and the porosity of the TC4 plate is 60-80%.

[0009] Preferably, the connecting hole group matched with the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate, the connecting hole group includes a plurality of first through holes, and the plurality of first through holes respectively correspond to the pore positions of the plurality of third pore groups.

[0010] Preferably, the pore group includes a first rectangular pore grouping and a second rectangular pore grouping opened on the top surface of the TC4 plate, the center of the first rectangular pore grouping is closed, the second rectangular pore grouping is arranged outside the first rectangular pore grouping, the pore diameter of the first rectangular pore grouping is smaller than the pore diameter of the second rectangular pore grouping, and the porosity of the TC4 plate is 70-85%.

[0011] Preferably, the connecting hole group matched with the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate, the connecting hole group includes a plurality of second through holes, and the plurality of second through holes respectively correspond to the pore positions of the plurality of second rectangular pore groupings.

[0012] Preferably, the pore group is composed of a plurality of pore spheres, the center of the top surface of the TC4 plate is open, and a plurality of the pore spheres are interconnected and arranged in the TC4 plate. The pore sphere is composed of a quadrilateral plate and a hexagonal plate to form a sphere, and the quadrilateral plate and the hexagonal plate are respectively provided with polygonal pores matching the number of their sides, and the porosity of the TC4 plate is 85-95%.

[0013] Preferably, the connecting hole group matched with the pore group is opened on the top surface of the titanium alloy 3D printing plate, the connecting hole group includes a plurality of third through holes, and the plurality of third through holes respectively correspond to the positions of the plurality of pore spheres.

[0014] The present invention discloses the following technical effects: the bottom bracket, the middle bracket and the porous polymer material layer cooperate with each other to form a bionic structure, which is designed according to the needs of bone and cartilage growth. The bottom bracket corresponds to the bone, the porous polymer material layer corresponds to the cartilage layer, and the middle bracket corresponds to the cortical bone to achieve separation and connection between the bottom bracket and the porous polymer material layer. From a physiological perspective, the synovial fluid is isolated from the blood to prevent the synovial fluid from having a negative impact on the proliferation and differentiation of bone marrow mesenchymal stem cells in the blood. From a bionic perspective, the physical and mechanical properties of the subchondral bone plate are imitated, which hinders the communication between the synovial fluid and the blood, connects the cartilage layer and the cancellous bone layer structure of the bracket, and plays a supporting role in mechanics.

[0015] The device can block blood and synovial fluid and enhance the connection strength, so it has better characteristics. The device is used for the damaged cartilage of the patient. The device is placed therein and cells are transplanted to make the cells proliferate and differentiate therein to achieve cartilage regeneration. The pore group is suitable for capturing cells and cell growth, allowing cells to enter the inside of the scaffold to avoid the cells growing only on the outside. The cells can flow into the inside of the scaffold through the high porosity on the outside to proliferate and differentiate, thereby enhancing the repair effect. The TC4 plate can help the regeneration of cancellous bone and cartilage in the entire tissue engineering repair process, and prevent excessive stress from being transmitted to the cancellous bone. The porous polymer material layer is polylactic acid-glycolic acid copolymer (PLGA), and Chinese medicine powder is added therein to greatly improve the efficiency of cartilage growth and differentiation. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 This is a schematic diagram of the structure of the bottom bracket in Example 1 of the present invention;

[0018] Figure 2 This is a schematic diagram of the structure of the middle support in Example 1 of the present invention;

[0019] Figure 3 is a schematic structural diagram of a porous polymer material layer in Example 1 of the present invention;

[0020] Figure 4 This is a schematic diagram of the structure of the bottom bracket in Example 2 of the present invention;

[0021] Figure 5 A schematic diagram of the structure of the middle support in Example 2 of the present invention;

[0022] Figure 6 A schematic diagram of the structure of the bottom bracket in Example 3 of the present invention;

[0023] Figure 7 A schematic diagram of the structure of the middle support in Example 3 of the present invention;

[0024] Figure 8 A schematic diagram of the structure of a tetrahedron in Example 3 of the present invention;

[0025] Fig. 9 A schematic diagram of the structure of a reinforcement column in Example 4 of the present invention;

[0026] Fig.10 A schematic diagram of the structure of the reinforcement tube in Example 5 of the present invention;

[0027] Among them, 1. porous polymer material layer; 2. TC4 plate; 3. titanium alloy 3D printing plate; 4. first pore grouping; 5. second pore grouping; 6. third pore grouping; 7. first through hole; 8. first rectangular pore grouping; 9. second rectangular pore grouping; 10. second through hole; 11. quadrilateral plate; 12. hexagonal plate; 13. third through hole; 14. reinforcement column; 15. first penetration hole; 16. reinforcement tube; 17. second penetration hole. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0030] Example 1

[0031] Reference Figure 1-3 , for young, middle-aged and elderly patients with good bone strength, this embodiment provides a stent for patients with osteoarthritis in different bone conditions, including: a bottom stent, a middle stent and a porous polymer material layer 1; the top surface of the bottom stent is fixedly connected to the bottom surface of the middle stent, and the top surface of the middle stent is fixedly connected to the bottom surface of the porous polymer material layer 1;

[0032] The bottom support is set as a multi-layer structure, and the bottom support is composed of a plurality of TC4 plates 2 stacked together. A pore group is opened on the top surface of the TC4 plate 2, and the pore groups of the plurality of TC4 plates 2 are vertically connected. The middle support is set as a titanium alloy 3D printing plate 3; a plurality of connecting hole groups adapted to the pore group are opened on the top surface of the titanium alloy 3D printing plate 3, and the bottom opening of the connecting hole group is connected with the pore groups of the plurality of TC4 plates 2. The top surface of the titanium alloy 3D printing plate 3 is fixedly connected to the bottom surface of the porous polymer material layer 1, and the bottom of the porous polymer material layer 1 closes the top opening of the connecting hole group.

[0033] The bottom bracket is integrally formed by additive manufacturing (3D printing) and then heat treated by stress relief annealing at 400-800 degrees and keeping warm for 3 hours.

[0034] The bottom bracket, middle bracket and porous polymer material layer 1 are arranged to cooperate with each other to form a bionic structure, which is designed according to the needs of bone and cartilage growth. The bottom bracket corresponds to the bone, the porous polymer material layer 1 corresponds to the cartilage layer, and the middle bracket corresponds to the cortical bone to achieve separation and connection between the bottom bracket and the porous polymer material layer 1, to achieve blocking of blood and synovial fluid and to enhance the connection strength, so it has better characteristics. The device is used for the damaged cartilage of the patient, and the device is placed therein, and cells are transplanted, so that the cells proliferate and differentiate therein, and the regeneration of cartilage is achieved. The pore group is suitable for capturing cells and cell growth, so that the cells enter the inside of the bracket, and avoid staying only on the surface, and enhance the repair effect. The TC4 plate 2 arranged can play a role in supporting cartilage in the entire tissue engineering repair process, and prevent excessive stress from being transmitted to cancellous bone. The porous polymer material layer 1 arranged is polylactic acid-glycolic acid copolymer (PLGA), and Chinese medicine powder is added therein to make it more cartilage growth and differentiation efficiency greatly improved.

[0035] The middle-layer support can also be made of polylactic acid (PLA) + graphene 5-15% or traditional Chinese medicine powder, polyetheretherketone (PEEK) or PEEK + graphene 5-15% or traditional Chinese medicine powder, polyimide (PI) or polyimide + graphene 5-15%.

[0036] According to a further optimization scheme, a plurality of mutually interwoven through holes are provided in the porous polymer material layer 1, and the apertures of the through holes gradually decrease from the outside to the inside.

[0037] The through holes are interwoven and connected with each other, which can enhance the proliferation of chondrocytes in the porous polymer material layer 1 and completely fill it.

[0038] According to a further optimized solution, Chinese medicine powder is distributed in the porous polymer material layer 1 .

[0039] Setting Chinese medicine powder can promote the proliferation of chondrocytes.

[0040] A further optimized solution is provided, wherein the pore groups include a first pore grouping 4, a second pore grouping 5 and a third pore grouping 6; the first pore grouping 4 is opened at the center of the top surface of the TC4 plate 2, a plurality of second pore groupings 5 ​​are opened outside the first pore grouping 4, the plurality of second pore groupings 5 ​​form a first rectangular structure on the top surface of the TC4 plate 2, the first pore grouping 4 is located at the center of the first rectangular structure, a plurality of third pore groupings 6 are opened outside the second pore grouping 5, the plurality of third pore groupings 6 form a second rectangular structure on the top surface of the TC4 plate 2, and the first rectangular structure is located at the center of the second rectangular structure; the first pore grouping 4, the second pore grouping 5 and the third pore grouping 6 all have a plurality of pores, the first pore grouping 4, the second pore grouping 5 and the third pore grouping 6 occupy the same area, and the number of pores of the first pore grouping 4, the second pore grouping 5 and the third pore grouping 6 gradually decreases, and the pore diameter gradually increases, and the porosity of the TC4 plate 2 is 60-80%.

[0041] A porosity setting of 60-80% may provide the optimal porosity for restoration in young, middle-aged, and elderly patients with good bone strength.

[0042] According to a further optimization scheme, a connecting hole group adapted to the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate 3, and the connecting hole group includes a plurality of first through holes 7, and the plurality of first through holes 7 respectively correspond to the pore positions of the plurality of third pore groups 6.

[0043] The top of the communicating hole group is blocked by the porous polymer material layer 1 to avoid the adverse effects caused by the blood and synovial fluid being connected and fused.

[0044] Example 2

[0045] Reference Figure 4-5 For middle-aged and elderly patients with average bone strength, the pore group in this embodiment includes a first rectangular pore grouping 8 and a second rectangular pore grouping 9 opened on the top surface of the TC4 plate 2. The center of the first rectangular pore grouping 8 is closed, and the second rectangular pore grouping 9 is sleeved outside the first rectangular pore grouping 8. The pore diameter of the first rectangular pore grouping 8 is smaller than the pore diameter of the second rectangular pore grouping 9. The porosity of the TC4 plate 2 is 70-85%.

[0046] A porosity setting of 70-85% may be the optimal porosity for restoration of middle-aged and elderly patients with normal bone strength.

[0047] A connecting hole group adapted to the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate 3 , and the connecting hole group includes a plurality of second through holes 10 , and the plurality of second through holes 10 respectively correspond to the pore positions of the plurality of second rectangular pore groups 9 .

[0048] Example 3

[0049] Reference Figure 6-8 For elderly patients with osteoporosis, the pore group in this embodiment is composed of a plurality of pore spheres. The center of the top surface of the TC4 plate 2 is open, and a plurality of pore spheres are interconnected and arranged in the TC4 plate 2. The pore sphere is composed of a quadrilateral plate 11 and a hexagonal plate 12 to form a sphere. The quadrilateral plate 11 and the hexagonal plate 12 are respectively provided with polygonal pores matching the number of their sides. The porosity of the TC4 plate 2 is 85-95%.

[0050] The porous sphere is formed by connecting fourteen faces (14 faces: 6 quadrilaterals and 8 hexagons), wherein the height, length and width of each fourteen face are 1 mm. The thickness of the external TC4 plate 2 is 0.1 mm.

[0051] A porosity setting of 85-95% may be the optimal porosity for restoration in elderly patients with osteoporosis.

[0052] A connecting hole group adapted to the pore group is opened on the top surface of the titanium alloy 3D printing plate 3, and the connecting hole group includes a plurality of third through holes 13, and the plurality of third through holes 13 respectively correspond to the positions of the plurality of pore spheres.

[0053] Example 4

[0054] Reference Fig. 9 The bottom bracket is provided with a plurality of reinforcing columns 14 for reinforcing the connection. The plurality of reinforcing columns 14 are arranged in the bottom bracket at equal intervals in the circumferential direction. The reinforcing columns 14 penetrate a plurality of TC4 plates 2. The plurality of TC4 plates 2 are arranged at intervals. A connecting cavity is provided in the reinforcing column 14. A plurality of first penetration holes 15 are provided on the outer wall of the reinforcing column 14. The first penetration holes 15 are connected to the connecting cavity. The TC4 plates 2 are fixedly connected to the reinforcing columns 14.

[0055] The reinforcement column 14 can not only strengthen the connection strength between the bottom brackets, but also leave gaps between adjacent TC4 plates 2, so that the implanted cells can be more connected with the cells at the damaged cartilage to form a whole. The setting of the first penetration hole 15 can realize the proliferation of cells.

[0056] Example 5

[0057] Reference Fig.10 A plurality of reinforcing tubes 16 are fixedly connected to the top and bottom surfaces of the titanium alloy 3D printing plate 3. The reinforcing tubes 16 are respectively inserted into the bottom bracket and the porous polymer material layer 1, and a second penetration hole 17 is opened on the wall of the reinforcing tube 16. The provided reinforcing tubes 16 can enhance the connection strength between the titanium alloy 3D printing plate 3 and the bottom bracket and the porous polymer material layer 1.

[0058] Example 6

[0059] The bottom bracket in this embodiment is composed of a plurality of TC4 plates 2 stacked together. The outer side of the TC4 plate 2 is designed to be cross-shaped by cylinders with a diameter of 1 mm. The middle part of the TC4 plate 2 is a solid open hole structure, and the hole diameter decreases stepwise from the outside to the inside. The middle hole diameter is small, and the outer hole diameter is large.

[0060] Example 7

[0061] The bottom bracket in this embodiment is composed of several TC4 plates 2 stacked together. The outer side of the TC4 plate 2 is designed to be cross-designed with 0.5mm diameter cylinders to form a 1.5mm*1.5mm pore structure. In the inner 1.5mm*1.5mm pore structure, a 0.5mm diameter cylinder is added at the 0.75mm position in the middle of each cylinder. The TC4 plate 2 is a fully solid structure. The pore diameter decreases from the outside to the inside in a step-like manner.

[0062] In the description of the present invention, it should be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0063] The embodiments described above are only descriptions of the preferred modes of the present invention, and are not intended to limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by ordinary technicians in this field should all fall within the protection scope determined by the claims of the present invention.

Claims

1. A stent for patients with osteoarthritis of different bone conditions, characterized in that: include: A bottom support, a middle support and a porous polymer material layer (1); the top surface of the bottom support is fixedly connected to the bottom surface of the middle support, and the top surface of the middle support is fixedly connected to the bottom surface of the porous polymer material layer (1); The bottom support is configured as a multi-layer structure, the bottom support is composed of a plurality of TC4 plates (2) stacked together, a pore group is provided on the top surface of the TC4 plate (2), the pore groups of the plurality of TC4 plates (2) are vertically connected, and the middle support is configured as a titanium alloy 3D printing plate (3); a plurality of connected pore groups matching the pore groups are provided on the top surface of the titanium alloy 3D printing plate (3), the bottom openings of the connected pore groups are connected to the pore groups of the plurality of TC4 plates (2), the top surface of the titanium alloy 3D printing plate (3) is fixedly connected to the bottom surface of the porous polymer material layer (1), and the bottom of the porous polymer material layer (1) closes the top opening of the connected pore group; The bottom bracket is provided with a plurality of reinforcing columns (14) for reinforcing the connection. The plurality of reinforcing columns (14) are arranged in the bottom bracket at equal intervals in the circumferential direction. The reinforcing columns (14) penetrate the plurality of TC4 plates (2). The plurality of TC4 plates (2) are arranged at intervals. A connecting cavity is provided in the reinforcing column (14). The outer wall of the reinforcing column (14) is provided with a plurality of first penetration holes (15). The first penetration holes (15) are connected to the connecting cavity. The TC4 plates (2) are fixedly connected to the reinforcing columns (14). A plurality of reinforcing tubes (16) are fixedly connected to the top and bottom surfaces of the titanium alloy 3D printing plate (3); the reinforcing tubes (16) are respectively inserted into the bottom support and the porous polymer material layer (1), and a second penetration hole (17) is opened on the wall of the reinforcing tube (16); the reinforcing tube (16) can enhance the connection strength between the titanium alloy 3D printing plate (3) and the bottom support and the porous polymer material layer (1).

2. The stent for patients with osteoarthritis of different bone conditions according to claim 1, characterized in that: The porous polymer material layer (1) is provided with a plurality of through holes which are interconnected and interwoven with each other.

3. The stent for patients with osteoarthritis of different bone conditions according to claim 1, characterized in that: Traditional Chinese medicine powder is distributed in the porous polymer material layer (1).

4. The stent for patients with osteoarthritis of different bone conditions according to claim 1, characterized in that: The pore groups include a first pore group (4), a second pore group (5) and a third pore group (6); the first pore group (4) is opened at the center of the top surface of the TC4 plate (2), a plurality of the second pore groups (5) are opened outside the first pore group (4), and the plurality of the second pore groups (5) form a first rectangular structure on the top surface of the TC4 plate (2), the first pore group (4) is located at the center of the first rectangular structure, a plurality of the third pore groups (6) are opened outside the second pore group (5), and a plurality of the third pore groups (6) are opened outside the second pore group (5). The group (6) forms a second rectangular structure on the top surface of the TC4 plate (2), and the first rectangular structure is located at the center of the second rectangular structure; the first pore group (4), the second pore group (5) and the third pore group (6) are all provided with a plurality of pores, and the first pore group (4), the second pore group (5) and the third pore group (6) occupy the same area, and the number of pores in the first pore group (4), the second pore group (5) and the third pore group (6) gradually decreases, and the pore diameter gradually increases, and the porosity of the TC4 plate (2) is 60-80%.

5. The stent for patients with osteoarthritis of different bone conditions according to claim 4, characterized in that: The connecting hole group matched with the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate (3), the connecting hole group includes a plurality of first through holes (7), and the plurality of first through holes (7) respectively correspond to the pore positions of the plurality of third pore groups (6).

6. The stent for patients with osteoarthritis of different bone conditions according to claim 1, characterized in that: The pore group comprises a first rectangular pore group (8) and a second rectangular pore group (9) opened on the top surface of the TC4 plate (2); the center of the first rectangular pore group (8) is closed, and the second rectangular pore group (9) is set outside the first rectangular pore group (8); the pore diameter of the first rectangular pore group (8) is smaller than the pore diameter of the second rectangular pore group (9); and the porosity of the TC4 plate (2) is 70-85%.

7. The stent for patients with osteoarthritis of different bone conditions according to claim 6, characterized in that: The connecting hole group matched with the pore group is opened at the edge of the top surface of the titanium alloy 3D printing plate (3), the connecting hole group includes a plurality of second through holes (10), and the plurality of second through holes (10) respectively correspond to the pore positions of the plurality of second rectangular pore groups (9).

8. The stent for patients with osteoarthritis of different bone conditions according to claim 1, characterized in that: The pore group is composed of a plurality of pore spheres. The center of the top surface of the TC4 plate (2) is open. The plurality of pore spheres are interconnected and arranged in the TC4 plate (2). The pore sphere is composed of a quadrilateral plate (11) and a hexagonal plate (12) to form a sphere. The quadrilateral plate (11) and the hexagonal plate (12) are respectively provided with polygonal pores matching the number of their sides. The porosity of the TC4 plate (2) is 85-95%.

9. The stent for patients with osteoarthritis of different bone conditions according to claim 8, characterized in that: The connecting hole group matched with the pore group is opened on the top surface of the titanium alloy 3D printing plate (3), the connecting hole group includes a plurality of third through holes (13), and the plurality of third through holes (13) respectively correspond to the positions of the plurality of pore spheres.

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