A method and device for characterizing the inhomogeneity of gels based on multi-field-of-view micro-rheology
Through multi-field microrheology technology, gel inhomogeneity is characterized, and the problems of too small probe particle concentration and scale limitation in the prior art are solved, thereby achieving high-precision characterization of gel multi-scale inhomogeneity.
CN115436230BActive Publication Date: 2025-07-01SOUTH CHINA UNIV OF TECH
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Patent Information
- Application Number
- CN202210978803.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-08-16
- Publication Date
- 2025-07-01
- Estimated Expiration
- 2042-08-16
AI Technical Summary
Technical Problem
When existing microrheometers characterize gel inhomogeneity, the small concentration of probe particles leads to insufficient accuracy and reliability of statistical results, and can only characterize the inhomogeneity scale less than one field of view.
Method used
Using multi-field microrheology technology, various observations are calculated to characterize the gel's inhomogeneity by adding probe particles to the gel and using a high-speed camera to capture thermal motion videos of particles under multiple fields of view.
Benefits of technology
A more accurate and reliable characterization of gel inhomogeneity is achieved, and a multi-scale characteristic of inhomogeneity changes can be fully characterized, improving the accuracy of gel material performance evaluation.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention discloses a method and device for characterizing the inhomogeneity of a gel based on multi-field micro-rheology. The method includes: adding probe particles to a gel prepolymer solution, obtaining a sample after subjecting the gel prepolymer solution to gelation treatment; placing the sample on a micro-rheometer, and using a high-speed camera to capture videos of the thermal motion of particles in multiple fields of view under a fluorescence microscope; positioning the probe particles on the sample according to the videos of the thermal motion of the particles, connecting the probe particles to obtain a coordinate sequence of the particle trajectories in each field of view, and obtaining all the particle trajectory data after traversing the data of each field of view; calculating various observables based on the particle trajectory data to characterize the inhomogeneity of the gel. The present invention is based on multi-field micro-rheology technology, provides a new method for the research and characterization of inhomogeneity, and can accurately and completely characterize the change of gel inhomogeneity. The present invention can be widely applied to the field of micro-rheology characterization.
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