Traditional Chinese and western combined pill iron horse pill

Abstract

The invention relates to Chinese and western patent medicines, in particular to a Chinese and western medicine composition for treating stubborn arthralgia. The traditional Chinese medicine composition is prepared from the following five traditional Chinese and western medicines: aconitum pendulum, semen strychni, VB1, diclofenac sodium and dexamethasone, still takes the traditional Chinese medicines as a mother agent and the western medicines as an auxiliary agent, has the characteristics of activating meridians to stop pain, removing stasis to subdue swelling and treating rheumatism and obstinate arthralgia, numbness and paralysis and traumatic injury, and has the characteristics of special medicine, strong effect, quick effect and no toxic or side effect.

Description

Technical field:

[0001] The invention relates to Chinese and western medicines, in particular to a Chinese and western medicine composition for treating stubborn arthralgia. Background technology:

[0002] Traditional Chinese medicine divides pain into three types: active arthralgia, painful arthralgia, and fixed arthralgia. Regardless of the type, if treated with Chinese medicine alone, although the efficacy is long-lasting, it has the characteristics of long treatment time and slow effect. Western medicine alone is effective relatively quickly, but it has the disadvantages of large side effects, short duration of efficacy, and high dependence.

[0003] Taking the advantages of the above two Chinese and Western medicines, making them effective quickly, without toxic side effects, and with a long duration of efficacy, taking their strengths and avoiding their weaknesses, Tiemadan has the advantages of both medicines, with rapid effects, long-lasting efficacy, and no toxic side effects. Summary of the invention:

[0004] The invention is composed of five Chinese and Western medicines, namely, iron hammer, strychnine, VB1, diclofenac sodium and dexamethasone, wherein the Chinese medicine is still used as the mother agent and the Western medicine is used as the auxiliary agent.

[0005] Since the poisoning amount and therapeutic amount of Chinese medicine Strychnos nux vomica are close, and the toxic and side effects of the iron club hammer are large, reducing its toxicity and preserving its medicinal properties are the research focuses of the present invention. Take an appropriate amount of the iron club hammer and Strychnos nux vomica according to the "Specific Implementation Method" and mix them with three Western medicines and Chinese medicines in proportion to grind into 120 mesh powder, make water pills with a diameter of φ6mm, sterilize and bottle for use. All patients with arthritis take 4 pills each time, take them with warm water in the morning and evening, 0.5g each time, and 1g per day.

[0006] Among them, the iron hammer can dispel wind and relieve pain, disperse blood stasis and stop bleeding, reduce swelling and remove toxins, and treat rheumatic joint pain, low back pain, traumatic injuries, sores and swelling, etc. The total alkaloids in the iron hammer have a strong analgesic effect, and its effect intensity is more than 40 times that of morphine. Its anesthetic effect is 14 times that of dicaine hydrochloride and 159 times that of procaine hydrochloride, but the toxicity is 40 times and 180 times respectively. Therefore, for safe use of drugs in clinical practice, toxicity must be reduced and detoxified. Please refer to the specific implementation method.

[0007] Among them, Strychnos nux vomica can dredge meridians and relieve pain, disperse nodules and reduce swelling, and treat rheumatism, pain, numbness, paralysis, bruises, carbuncle, swelling and pain, and rheumatism. Please refer to the following specific implementation method for the preparation of Strychnos nux vomica.

[0008] Whether continuous use of timadan can cause cumulative poisoning, medicine is three-point poison, and Chinese medicine has always advocated stopping taking it when the disease is cured, and not taking it excessively or for a long time. If the amount taken orally and the amount discharged are not considered (i.e. the amount discharged is greater than the amount taken orally), both astragalus and ginseng are poisons. The present invention uses vitamin B1 to promote metabolism and digestion to ensure normal discharge of the digestive system. VB1 participates in the formation of coenzymes in the body, maintains normal sugar metabolism and digestive system function, and VB1 is non-toxic.

[0009] Diclofenac sodium has antipyretic, analgesic and anti-inflammatory effects, and is suitable for non-articular soft tissue rheumatic pain, acute mild to moderate pain, adjuvant treatment of severe infectious pain, arthritis, trauma, postoperative inflammatory swelling, and gynecological inflammation, etc. It plays a synergistic and adjuvant therapeutic role with iron club hammer and nux vomica in iron horse dan.

[0010] Dexamethasone in Tiema Dan plays the role of suppressing and regulating immunity, and has good anti-inflammatory effect. It can restore the inflammatory edema caused by nucleus pulposus herniation and nerve or blood vessel compression caused by rupture of the intervertebral disc annulus fibrosus, so as to relieve pain faster. Since Tiema Dan is a traditional Chinese medicine passed down for generations, Tripterygium wilfordii was used in the original formula. In the past decade, it has been further improved to replace the traditional Chinese medicine hormone Tripterygium wilfordii with Western medicine hormones, which makes the drug effect work faster. Specific implementation method:

[0011] 1. Take 100g of iron stick and steam until 80% cooked, then slice and set aside.

[0012] 2. Mix 2500g of raw Strychnos nux vomica with iron hammer slices, then add 5200g of raw licorice slices into a stainless steel cellar, add water to cover about 5 fingers and soak for 24 hours.

[0013] 3. Use high heat to decoct the above three Chinese medicines for 90 minutes. Turn off the heat when the water is almost gone but not yet gone. After cooling, pick out the strychnine seeds and iron hammer slices for later use.

[0014] 4. Use coarse sand to stir-fry the strychnine and iron hammer pieces. Fry until the core of the strychnine is reddish brown and the iron hammer pieces are dark brown. The heat is just right. After cooling, clean up the sand and set aside.

[0015] 5. Take 5g of western medicine dexamethasone, 800g of diclofenac sodium, and 50g of vitamin B1 and mix them with the above two Chinese medicines (strychnos nux vomica and iron hammer), and process them into 120 mesh fine powder for later use.

[0016] 6. Process the above mixture into fine powder into φ6mm water pills, sterilize and package them for later use.

[0017] 7. For patients with arthritis, take 4 pills each time, once in the morning and once in the evening after meals, with warm water.

[0018] In every 4 pills of the finished medicine, after removing ineffective ingredients such as adhesives and flavoring agents, the following effective dosage must be ensured: 0.25g of processed strychnine, 0.01g of processed iron hammer, 0.0005g of dexamethasone, 0.08g of diclofenac sodium, and 0.005g of vitamin B1.

[0019] The above seven steps involve steaming, soaking, boiling and frying the seeds of Strychnos nux vomica and iron hammer, which truly reduces their toxicity while retaining their medicinal properties. After many years of clinical use, no medical accidents have occurred.

[0020] Typical cases:

[0021] Zhao Mouqin, female, 42 years old, was first diagnosed on February 2, 2021. She complained of multiple joint swelling and pain, recurrent attacks, pain relief with heat, preference for heat and fear of cold, white greasy tongue coating, deep and thin pulse, and stiff fingers every morning. Stomach cold, pain and swelling, laboratory test results showed increased erythrocyte sedimentation rate, increased r-globulin, increased Ig, and positive rheumatoid factor. Chinese medicine dialectics: spleen and kidney yang deficiency, meridian obstruction, treatment method: invigorate the spleen and kidney to dispel cold, promote blood circulation and remove blood stasis, remove dampness and dredge collaterals, give Tiema Dan 4 pills each time, 2 times / day, and take Jinkui Shenqi Pills and Buzhong Yiqi Pills. At the second visit half a month later, except for a slightly faster erythrocyte sedimentation rate, other indicators were normal. She complained that her stomach was no longer painful or swollen. In order to consolidate the therapeutic effect, she continued to take Tiema Dan and Buzhong Yiqi Pills, and a course of Jinkui Shenqi Pills to consolidate its effect.

[0022] Wang, male, 52 years old, first diagnosed on May 30, 2021. He complained of multiple joint swelling and pain, deformed finger joints, morning stiffness, red tongue tip, yellow tongue coating, deep, thin pulse and weak pulse. He reported a course of more than 3 years. Previous laboratory tests showed accelerated erythrocyte sedimentation rate, increased beta and gamma globulins and immunoglobulins. Cellular immune function was low, rheumatoid factor was positive, X-ray examination: obvious bone destruction, joint dislocation, ankylosis, Chinese medicine syndrome differentiation: Qi, blood, yin and yang are both deficient, liver and kidney are deficient. Treatment: ① Take 4 pills of Tiema Dan, 2 times / day, 14 days per course; ② Take decoction: Chuanduan 15g, Guzi 15g, Gusuanbu 2g, Xianlingpi 15g, Dihuang 20g, Niuxi 15g, Paoshanjia 10g, Danshen 15g, Shengyiren 30g, Zirougui 5g, Honghua 10g, Tianma 15g, Shengsun ginseng 15g, take it continuously for 14 days. ③ Combined with acupuncture treatment, once every other day for a total of seven times, Shenshu (double), Mingmen (single), Huantiao (double), Weizhong (double), Chengshan (double), Zusanli (double), Guanyuan (single), Qihai (single), Dazhui (single), Ganshu (double), pricking and bleeding at the deformed parts of both fingers. Second diagnosis after May 18: Rheumatoid factor has turned negative, mental state has improved significantly, and swelling in all joints has disappeared. Give Tiemadan again for half a month to consolidate its effect.

[0023] Cui Moumou, female, 26 years old, first diagnosed on May 5, 2021, with symptoms of pale face and lips, fatigue, spontaneous sweating, palpitations, poor appetite, dizziness, greasy tongue coating and thin pulse. The test report showed: positive rheumatoid factor. Erythrocyte sedimentation rate and C-reactive protein were abnormal, showing both qi and blood deficiency. The treatment should be to replenish qi and blood, but not to replenish sharply, but to slow down the picture, and pay attention to dispelling wind and dampness. Prescriptions used: Pseudostellaria baicalensis, Astragalus membranaceus, Millettia reticulata, Atractylodes macrocephala, White peony root, jujube, dried ginger, stir-fried Atractylodes macrocephala, Coix seed, etc., Saposhnikovia divaricata, moxibustion Chuanwu, etc., and Tiema Dan was added for 20 days. At the second visit 20 days later, the three rheumatism items turned negative, the rheumatoid factor turned negative, all symptoms were eliminated, and the spirit improved. Another course of Tiema Dan was given to consolidate the therapeutic effect.

[0024] Efficacy statistics:

[0025] A total of 60 cases of arthritis were treated with timadan, with the results showing that 1 case was clinically cured, accounting for 1.7%, 27 cases were markedly effective, accounting for 45%, and 26 cases were effective, accounting for 43%. The total effective rate was 90%.

Claims

1. The present invention is a combination pill of Chinese and Western medicine, characterized in that The formula and the weight of each Chinese and Western medicine are: 0.25g of processed Strychnos nux vomica, 0.01g of processed iron hammer, 0.0005g of dexamethasone, 0.08g of diclofenac sodium, and 0.005g of vitamin B1.