Probiotic honey dew as well as production process and application thereof

Abstract

The invention discloses probiotic honey dew as well as a production process and application thereof. The production process comprises the following steps: S1, preparing materials; s2, performing pretreatment; s3, mixing and stirring; s4, performing filling; in the stirring process in the step S3, casual inspection is carried out on the mixture at any time to determine whether sediment exists or not; wherein the precipitate is subjected to initial inspection and reinspection, so that the purity of the mixture is improved. According to the present invention, the constipation problem can be timely solved, and almost no side effect is generated; meanwhile, the probiotic flora is added into the formula, so that the constipation treatment effect is enhanced, multiple effects of improving the intestinal probiotic flora, improving the immunity and the like are achieved, and dietary fibers can be effectively supplemented and intestinal peristalsis can be promoted by adding the prune juice and the grapefruit juice; by adding the small molecule peptide, peptides and amino acids required by metabolism of intestinal cells can be effectively supplemented, and the effect of repairing intestinal tracts can be achieved.

Description

Technical Field

[0001] The present application relates to the technical field of laxative enema medicines, and in particular to a probiotic honey dew and a production process and application thereof. Background Art

[0002] Constipation is currently a common anorectal disease, which refers to hardened stool, difficulty or incomplete defecation, and reduced bowel movement. In the most extensive practice, enema or pediatric enema (quick type) is used, in which the active ingredient that exerts a mechanical effect in the intestine is hyaluronic acid or its analog. However, although single hyaluronic acid (or a composition mainly based on hyaluronic acid) can effectively induce intestinal peristalsis, thereby promoting excretion, it will produce adverse reactions, such as abdominal cramps, and in the case where the constipated subject itself has been stimulated and dehydrated, the mucosa is further stimulated and / or dehydrated. In other words, hyaluronic acid has no beneficial and / or protective effect on intestinal mucosa, which leads to the use of hyaluronic acid as the main agent with excretion, which is usually accompanied by low tolerance of constipated subjects.

[0003] In the related art, a Chinese patent with a patent publication number of CN114027479A proposes a method for preparing microencapsulated probiotic honey; the steps include: preparation of probiotic honey fermentation liquid, preparation of probiotic microcapsules and preparation of microencapsulated probiotic honey; the present invention adopts an emulsification method to microencapsulate the probiotics in the prepared probiotic honey fermentation liquid with erythritol-modified carboxyl maltose coating, which has the advantages of simple operation, high embedding rate, and no mechanical damage to the bacteria, and is very suitable for current probiotic production and processing. After the probiotics of the present invention are microencapsulated, the probiotics can be protected from the action of bacteriophages, the survival rate of freeze-drying can be improved, and the stability in honey storage can be ensured. More importantly, the survival rate in intestinal fluid can be significantly improved, the probiotic effect can be improved, and the probiotic effect can be fully exerted.

[0004] Regarding the above-mentioned related technologies, the inventors believe that there are the following defects: in the process of preparing raw materials, the mixed raw materials need to be filtered to prevent the presence of impurities, crystals or other microbial metabolites in the raw materials. However, if most of them are currently filtered once, there may still be other operations in the subsequent operations that may cause impurities to enter the solution. If not filtered, it will affect the quality of the subsequent honey dew product. Summary of the invention

[0005] In order to improve the problem of precipitation still existing in the mixed liquid, the present application provides a probiotic honey dew and its production process and application.

[0006] The production process of a probiotic honey dew provided in this application adopts the following technical solution: A production process of probiotic honey dew comprises the following steps: S1. Prepare materials: honey, probiotics and other auxiliary materials need to be prepared according to the composition ratio; S2, pretreatment: heating, dissolving and filtering the raw materials to ensure the purity and uniformity of the raw materials; S3, mixing and stirring: putting the pretreated raw materials into a mixing device, stirring and mixing them fully to form a stable mixture; S4, filling: injecting the evenly mixed probiotic honey dew into a pre-prepared container through a filling device; During the stirring process of step S3, the mixture needs to be randomly inspected at any time to see if there is any precipitate; wherein the precipitate is initially inspected and re-inspected to improve the purity of the mixture; The sampling step uses a detection device to detect whether there is sediment, and the detection device includes a sampling mechanism, a viewing mechanism for initial inspection of the sediment, and a review mechanism for re-inspecting the sediment that cannot be detected by the viewing mechanism; The sampling mechanism includes a bracket arranged on the mixing device, a sampling frame lifted and lowered on the bracket, a plurality of sampling tubes elastically arranged on the bracket, a plurality of first solenoid valves, an identification component for marking the liquid level in the sampling tube, and a reciprocating component for controlling the reciprocating motion of the sampling tube. The sampling tube is provided with a water inlet, and the first solenoid valve is arranged at the water inlet.

[0007] Optionally, the reciprocating assembly includes a reciprocating box, a reciprocating rod, a first electromagnet and a reciprocating part for controlling the reciprocating motion of the first electromagnet, the bottom end of the sampling tube is fixedly connected to a first spring, the sampling box is provided with a reciprocating hole for the reciprocating rod to pass through, the first spring is sleeved outside the reciprocating rod and the bottom end of the spring is fixedly connected to the sampling box.

[0008] Optionally, the identification component includes an identification box arranged on the side wall of the sampling tube, an identification cavity arranged in the identification box, a floating plate floating in the identification cavity, a proximity switch arranged on the top of the identification box, and a water inlet, the bottom of the final resting position of the floating plate is in the same horizontal plane as the set liquid level in the sampling tube, one end of the water inlet is connected to the sampling tube and the other end is connected to the identification cavity, and the proximity switch is electrically connected to a buzzer.

[0009] Optionally, the viewing mechanism includes a viewing hood, a light source plate slidably arranged in the viewing hood, and a plurality of cameras; the viewing hood is fixed on the bracket, and the viewing hood covers the plurality of sampling tubes; transparent plates are arranged on two opposite sides of the sampling tubes; the light source plate and the cameras are respectively facing the two transparent plates.

[0010] Optionally, the review mechanism includes a review box, a frame, a non-woven fabric, a shaking component for shaking the non-woven fabric, a checking mechanism for reviewing the precipitate, and a recovery component for recovering the precipitate. One end of the review box is connected to the bottom side wall of the sampling tube, and a second solenoid valve is provided at the connection position. The frame is rotatably arranged in the review box and the review box is adapted to the frame. A rotating motor for controlling the rotation of the frame is provided on the inner wall of the review box, and the non-woven fabric is elastically arranged in the frame.

[0011] Optionally, the shaking assembly includes a shaking plate, a connecting block, a protective box, a connecting rod, a protrusion, a cam, a second spring and a shaking motor for controlling the rotation of the cam, one end of the non-woven fabric is fixedly connected to the frame, the shaking plate is connected to the other end of the non-woven fabric, the shaking plate is slidably adapted in the frame, the connecting block is fixedly connected to the upper end of the shaking plate, the protective box is arranged on the frame and the protective box is provided with a through hole for the connecting rod to pass through, one end of the connecting rod is connected to the connecting block, the other end of the connecting rod slides in the protective box, the protrusion is fixedly connected to one end of the connecting rod located in the protective box, the cam is rotatably connected to the protective box, the protrusion of the cam abuts against the outer wall of the connecting block, one end of the connecting rod located in the protective box is also fixedly connected to the second spring, and the other end of the second spring is fixedly connected to the inner wall of the protective box.

[0012] Optionally, the verification assembly includes a rotating rod rotatably arranged at the top of the verification box, a verification motor for controlling the rotation of the rotating rod, a picking ring fixed at the end of the rotating rod, a verification plate, a plurality of verification ropes and a tension sensor, one end of the picking ring is open, the verification plate is fixed at the end of the rotation direction of the picking plate, a plurality of verification holes are arranged in the circumferential wall of the picking ring, one end of the verification rope is fixedly connected to one end of the verification hole, and the other end is fixedly connected to the circumferential wall of the verification plate, a plurality of verification ropes are evenly spaced on the circumferential wall of the verification plate, the original area of ​​the verification plate is larger than the inner diameter of the picking ring and the verification plate is in contact with the end of the picking ring.

[0013] Optionally, the recycling component includes an adhesive movably disposed in the verification box, a plurality of winding ropes and a winding component for winding the adhesive, the adhesive being movably disposed under the non-woven fabric, and the winding rope being located under the non-woven fabric when the non-woven fabric is filtering.

[0014] The probiotic honey dew provided in this application adopts the following technical solution: A probiotic honey dew comprises the following components: 74% honey, 5% probiotics, 0.5% small molecule peptides, 10% prune juice, 10% grapefruit juice, and 0.5% hyaluronic acid, wherein the probiotics are composed of a combination of multiple strains of Bifidobacterium lactis HN019, Bifidobacterium lactis Bi-07, Lactobacillus acidophilus NCFM, Bifidobacterium animalis Bb-12, Lactobacillus rhamnosus LGG, and Lactobacillus rhamnosus HN001.

[0015] The present application provides the use of the above-mentioned probiotic honey solution in the clinical treatment of constipation.

[0016] In summary, the present application includes at least one of the following beneficial technical effects: 1. Improve constipation: Promote intestinal motility: Probiotic honey contains a certain amount of probiotics, which can promote gastrointestinal motility, thereby helping to relieve constipation symptoms. Honey itself also has a good laxative effect, which can further promote defecation; Improve body immunity: Rich in nutrients: Probiotic honey contains rich nutrients such as protein, vitamins, glucose, and trace elements such as calcium, potassium, and magnesium. These ingredients can provide the body with necessary nutritional supplements; Regulate intestinal flora: The role of beneficial bacteria: The probiotics in probiotic honey can colonize and reproduce in the intestines, forming a competitive relationship with harmful bacteria, thereby regulating the balance of intestinal flora. Promote nutrient absorption: Balanced intestinal flora helps promote the digestion and absorption of nutrients and maintain intestinal health; 2. When the sampling tube moves to the corresponding position, the movement of the first electromagnet is controlled by the reciprocating member. The reciprocating member can be an electric push rod. Therefore, the first electromagnet drives the reciprocating rod to continue to move downward, and the sampling tube continues to compress the first spring. After the first spring is compressed, the first electromagnet is powered off. Under the elastic force of the first spring, the sampling tube begins to move upward, and the solution in the sampling tube vibrates. After reciprocating for many times, the solution in the sampling tube moves violently, and the precipitation inside is evenly distributed and moves violently in the solution. It is irradiated by the light source board and photographed by a general camera. The staff watches the situation in the solution displayed on the screen. If the precipitation is distributed more, the movement of the precipitation in the solution can be easily found at this time, and no subsequent review agency needs to review it. However, if the precipitation is not distributed much, it is judged that there may be a problem, so the review agency needs to review it; 3. When the non-woven fabric shakes and precipitates, the control check motor drives the rotating rod to rotate, and the rotating rod drives the pick-up ring to move toward the non-woven fabric. One end of the pick-up ring first moves to the precipitate, and as the rotating rod continues to rotate, the pick-up ring takes the precipitate from the non-woven fabric, and the precipitate falls on the check sheet. If there is precipitate on the check sheet, the tension sensor monitors the change in tension at the first time. The tension sensor can be electrically connected to the display screen or the buzzer. As long as the tension sensor receives a signal, the buzzer sounds an alarm or the display screen displays a number, which proves that there is precipitate in the solution and the solution needs to be filtered again. Finally, swing the rotating rod in the other direction, the opening of the pick-up ring faces the non-woven fabric, and the precipitate falls on the non-woven fabric. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a process flow chart of Example 2 of the present application; Figure 2 It is a schematic diagram of the overall structure of the first embodiment of the present application; Figure 3 is a schematic diagram of the detection device in Example 1 of the present application; Figure 4 It is a schematic diagram of the viewing mechanism in the first embodiment of the present application; Figure 5 It is a schematic diagram of the review structure in Example 1 of the present application; Figure 6 yes Figure 5 The enlarged view of point A in the middle; Figure 7 It is a schematic diagram of the retrieval ring, verification sheet, verification rope and tension sensor in Example 1 of the present application.

[0018] Figure numerals: 1, bracket; 2, sampling rack; 3, sampling tube; 4, first solenoid valve; 5, water inlet; 6, reciprocating box; 7, reciprocating rod; 8, first electromagnet; 9, reciprocating member; 10, first spring; 11, identification box; 12, identification cavity; 13, floating plate; 14, proximity switch; 15, buzzer; 16, water inlet; 17, viewing cover; 18, light source board; 19, camera; 20, transparent board; 21, review box; 2 2. Frame; 23. Non-woven fabric; 24. Second solenoid valve; 25. Rotating motor; 26. Shaking plate; 27. Connecting block; 28. Connecting rod; 29. ​​Protective box; 30. Bump; 31. Cam; 32. Second spring; 33. Shaking motor; 34. Perforation; 35. Rotating rod; 36. Pick-up ring; 37. Verification sheet; 38. Verification rope; 39. Tension sensor; 40. Adhesive; 41. Winding roller; 42. Winding rope. DETAILED DESCRIPTION

[0019] The following is combined with Figure 1-7 This application is described in further detail. Embodiment 1

[0020] The present application embodiment discloses a production process of probiotic honey dew. Figure 1 A production process of probiotic honey dew includes the following steps: S1. Prepare materials: honey, probiotics and other auxiliary materials need to be prepared according to the component ratio; in this embodiment, the relative proportions of each component are 74% honey, 5% probiotics, 0.5% small molecule peptides, 10% prune juice, 10% grapefruit juice, and 0.5% hyaluronic acid. The probiotics are composed of a variety of bacterial species including Bifidobacterium lactis HN019, Bifidobacterium lactis Bi 07, Lactobacillus acidophilus NCFM, Bifidobacterium animalis Bb12, Lactobacillus rhamnosus LGG, and Lactobacillus rhamnosus HN001.

[0021] S2. Pretreatment: Heat, dissolve and filter the raw materials to ensure the purity and uniformity of the raw materials; heating is required here to remove the crystals of honey.

[0022] S3, mixing and stirring: putting the pretreated raw materials into a mixing device, stirring and mixing them fully to form a stable mixture; S4, filling: injecting the evenly mixed probiotic honey dew into a pre-prepared container through a filling device; Reference Figure 1-Figure 4 During the stirring process of step S3, the mixture needs to be randomly checked at any time to see if there is any precipitate; the precipitate is initially checked and re-checked to improve the purity of the mixture; the random inspection step uses a detection device to detect whether there is any precipitate, and the detection device includes a random inspection mechanism, a viewing mechanism for initially checking the precipitate, and a review mechanism for re-checking the precipitate that the viewing mechanism cannot detect; the solution is firstly treated by the random inspection mechanism, and then a simple processing method, i.e., the viewing mechanism, is used to view it, and finally, if it cannot be determined by the light viewing method, it is necessary to determine whether there is any precipitate through a review mechanism, and if there is any precipitate, the solution needs to be filtered.

[0023] The sampling mechanism includes a bracket 1 arranged on the mixing device, a sampling frame 2 lifted and arranged on the bracket 1, multiple sampling tubes 3 elastically arranged on the bracket 1, multiple first solenoid valves 4, an identification component for identifying the liquid level in the sampling tube 3 and a reciprocating component for controlling the reciprocating motion of the sampling tube 3. The sampling tube 3 is provided with a water inlet 5, and the solenoid valve is arranged at the water inlet 5. The sampling tube 3 can be set to multiple, that is, solutions of different depths can be sampled, and the accuracy of the sampling inspection will be higher. In this embodiment, a sampling tube 3 is used as an example for explanation. The position of the water inlet 5 is set at a position close to the bottom of the sampling tube 3, and in this embodiment, the impression needs to shake the sampling tube 3, so the sampling tube 3 does not need to be filled, so it is marked by the identification component.

[0024] Reference Figure 1-Figure 4 The identification component includes an identification box 11 arranged on the side wall of the sampling tube 3, an identification cavity 12 arranged in the identification box 11, a floating plate 13 floatingly arranged in the identification cavity 12, a proximity switch 14 and a water inlet 16 arranged on the top of the identification box 11. In this embodiment, the bottom of the final stop position of the floating plate 13 is in the same horizontal plane as the set liquid level in the sampling tube 3. One end of the water inlet 16 is connected to the sampling tube 3 and the other end is connected to the identification cavity 12. The proximity switch 14 is electrically connected to a buzzer 15. The proximity switch 14 and the buzzer 15 are controlled and connected by a PLC controller. The floating plate 13 is made of a material with greater buoyancy. In this embodiment, a clamping structure is set at the upper end opening of the floating plate 13 and the floating cavity, that is, two triangular blocks cooperate with each other, that is, the floating plate 13 is limited to the top of the floating cavity; the lifting and lowering of the sampling rack 2 is controlled by an electric push rod Or it can be realized by the cylinder. After the sampling rack 2 drives the sampling tube 3 to the specified position, the first solenoid valve 4 is opened at this time, and the solution enters the sampling tube 3 from the inlet. As the solution enters the sampling tube 3, the solution also enters the identification chamber 12, and the floating plate 13 begins to float in the floating chamber. As the liquid level in the sampling tube 3 continues to rise to the specified liquid level, the floating plate 13 also floats to the highest position. At this time, the lowest surface of the floating plate 13 is at the same horizontal plane as the liquid level of the sampling tube 3, and the top of the floating plate 13 just contacts the proximity switch 14, and the proximity switch 14 triggers the buzzer 15 to start the alarm. Of course, the proximity switch 14 and the first solenoid valve 4 can also be controlled and connected by different PLC controllers. When the floating plate 13 contacts the proximity switch 14, the buzzer 15 starts to alarm and the first solenoid valve 4 is closed to extract the sampling tube 3 from the solution.

[0025] The reciprocating assembly includes a reciprocating box 6, a reciprocating rod 7, a first electromagnet 8 and a reciprocating member 9 for controlling the reciprocating motion of the first electromagnet 8. The bottom end of the sampling tube 3 is fixedly connected with a first spring 10. The sampling box is provided with a reciprocating hole for the reciprocating rod 7 to pass through. The first spring 10 is sleeved outside the reciprocating rod 7 and the bottom end of the spring is fixedly connected to the sampling box. The reciprocating rod 7 is adapted to the reciprocating hole, so the solution will not enter the reciprocating box 6. The first spring 10 is a spring with relatively large elastic force. As the solution in the sampling tube 3 continues to enter, the first spring 10 is also in a squeezed state, but it can continue to be compressed, that is, the first spring 10 is not at the compression limit when it is compressed by the sampling tube 3.

[0026] The viewing mechanism includes a viewing cover 17, a light source board 18 slidably arranged in the viewing cover 17, and a plurality of cameras 19. The viewing cover 17 is fixed on the bracket 1, and the viewing cover 17 covers a plurality of sampling tubes 3. Transparent plates 20 are arranged on two opposite sides of the sampling tubes 3. The light source board 18 and the cameras 19 are respectively opposite to the two transparent plates 20. The bottom end of the viewing cover 17 is opened for the sampling tubes 3 to enter, and the sampling tubes 3 are just blocked by the viewing cover 17 to enhance the lighting effect. One side of the light source board 18 is transparent glass, and a plurality of light bulbs are selected inside to form a plurality of sampling tubes 3. The transparent plate 20 is made of glass. When the sampling tube 3 completes sampling, the sampling tube 3 is pulled into the viewing cover 17. Although one sampling tube 3 is provided in the present embodiment, even if there are a plurality of sampling tubes 3, the light source board 18 can still illuminate the sampling tube 3. When the sampling tube 3 moves to After the corresponding position, the movement of the first electromagnet 8 is controlled by the reciprocating member 9. The reciprocating member 9 can be an electric push rod. Therefore, the first electromagnet drives the reciprocating rod 7 to continue to move downward, and the sampling tube 3 continues to compress the first spring 10. After the first spring 10 is compressed, the first electromagnet 8 is powered off. Under the elastic force of the first spring 10, the sampling tube 3 begins to move upward, and the solution in the sampling tube 3 vibrates. After reciprocating for many times, the solution in the sampling tube 3 moves violently, and the precipitation inside it is evenly distributed and moves violently in the solution. It is illuminated by the light source board 18 and photographed by a general camera 19. The staff watches the situation in the solution displayed on the screen. If the precipitation is distributed more, the movement of the precipitation in the solution can be easily found at this time, and there is no need for subsequent review by a review agency. However, if the precipitation is not distributed much, it is judged that there may be a problem, so a review agency is required to review it.

[0027] Reference Figure 5-Figure 7The review mechanism includes a review box 21, a frame 22, a non-woven fabric 23, a shaking component for shaking the non-woven fabric 23, a checking mechanism for checking the sediment, and a recovery component for recovering the sediment. After the shaking component shakes the sediment, it accelerates its rapid drainage and can also concentrate the sediment, so that the checking mechanism can be used to quickly judge the sediment. One end of the review box 21 is fixedly connected to the bottom side wall of the sampling tube 3, and a second solenoid valve 24 is provided at the connection position. The frame 22 rotates in the review box 21 and the review box 21 is adapted to the frame 22. A rotating motor 25 for controlling the rotation of the frame 22 is provided on the inner wall of the review box 21. The non-woven fabric 23 is elastically arranged in the frame 22. The rotation axis of the frame 22 and the review box 21 is located on the symmetric plane of the frame 22, so that the frame 22 can be rotated in the review box 21. The non-woven fabric 23 is in a naturally drooping state in the initial state, and the non-woven fabric 23 moves along its length.

[0028] The shaking assembly includes a shaking plate 26, a connecting block 27, a protective box 29, a connecting rod 28, a protrusion 30, a cam 31, a second spring 32 and a shaking motor 33 for controlling the rotation of the cam 31. One end of the non-woven fabric 23 is fixedly connected to the frame 22, and the shaking plate 26 is connected to the other end of the non-woven fabric 23. The shaking plate 26 is slidably adapted in the frame 22. When the shaking plate 26 has not yet been attached to the other end of the frame 22, the non-woven fabric 23 is in a naturally drooping state, and when the shaking plate 26 is attached to one end of the frame 22, the non-woven fabric 23 is in a straightened state; the connecting block 27 is fixedly connected to the upper end of the shaking plate 26, one end of the connecting rod 28 is fixedly connected to the connecting block 27, the protective box 29 is arranged on the frame 22 and the protective box 29 is provided with a through hole 34 for the connecting rod 28 to pass through, and the connecting The rod 28 is slidably matched with the perforation 34, so there is no solution entering the perforation 34. The other end of the connecting rod 28 slides in the protective box 29, and the protrusion 30 is fixedly connected to the end of the connecting rod 28 located in the protective box 29. The cam 31 is rotatably connected to the protective box 29, and the raised portion of the cam 31 abuts against the side wall of the connecting block 27. The end of the connecting rod 28 located in the protective box 29 is also fixedly connected to the second spring 32, and the other end of the second spring 32 is fixedly connected to the inner wall of the protective box 29; and when the non-woven fabric 23 is in a stretched state, the second spring 32 is in a natural state. In order to prevent the solution from pulling the non-woven fabric 23 when passing through the non-woven fabric 23, a limit electromagnet can be further provided in the protective box 29 at this time. The limit electromagnet adsorbs the connecting rod 28, and the position of the non-woven fabric 23 is limited at this time.

[0029] When the non-woven fabric 23 needs to be filtered, the non-woven fabric 23 is straightened so that the shaking plate 26 is fitted with one end of the frame 22, and the second solenoid valve 24 is opened. The non-woven fabric 23 filters the solution, and the limit electromagnet adsorbs the connecting rod 28. When the filtration is completed, the limit electromagnet releases the connecting rod 28. At this time, the shaking motor 33 rotates, and the raised part of the cam 31 moves the connecting block 27 toward the outer foundation of the protective box 29. At this time, the second spring 32 is in a stretched state. If the cam 31 is separated from the connecting block 27, under the elastic force of the second spring 32, the shaking plate 26 drives the non-woven fabric 23 to move quickly toward the end of the frame 22. At this time, the non-woven fabric 23 shakes upward on the sediment above it, and the sediment located on the side of the non-woven fabric 23 gradually gathers toward the bottom of the non-woven fabric 23 as the non-woven fabric 23 naturally droops, thereby achieving the effect of accelerating sedimentation drainage and sedimentation collection.

[0030] Reference Figure 5-Figure 7 The checking component includes a rotating rod 35 rotatably arranged at the top of the review box 21, a checking motor for controlling the rotation of the rotating rod 35, a picking ring 36 fixed at the end of the rotating rod 35, a checking piece 37, a plurality of checking ropes 38 and a tension sensor 39. During the entire filtering process, the liquid level in the checking box will not reach the position of the picking ring 36. The axial direction of the rotating rod 35 is perpendicular to the movement direction of the shaking plate 26. The bottom end of the rotating rod 35 just moves to the height when the non-woven fabric 23 naturally droops. One end of the picking ring 36 is opened, and the end of the picking ring 36 along its rotation direction is opened. The checking piece 37 is fixed to the end of the picking piece. A plurality of checking holes are arranged in the peripheral wall of the picking ring 36. The plurality of checking holes correspond to the plurality of checking ropes 38, and one end of the checking rope 38 is fixedly connected to one end of the checking hole, and the other end is fixedly connected to the peripheral wall of the checking piece 37. The plurality of checking ropes 38 are evenly spaced and distributed on the checking piece 37. The surrounding wall of the check sheet 37, the original area of ​​the check sheet 37 is larger than the inner diameter of the picking ring 36 and the check sheet 37 is in contact with the end of the picking ring 36, and the tension sensor 39 is used to connect any one of the check ropes 38; when the non-woven fabric 23 has shaken off the sediment, the control check motor is now controlled to drive the rotating rod 35 to rotate, and the rotating rod 35 drives the picking ring 36 to move in the direction of the non-woven fabric 23, and the open end of the picking ring 36 first moves to the sediment, and as the rotating rod 35 continues to rotate, the picking ring 36 takes the sediment from the non-woven fabric 23, and the sediment falls on the check sheet 37. If there is sediment on the check sheet 37, the tension sensor 39 monitors the change in tension at the first time. Here, the tension sensor 39 can be electrically connected to the display screen or the buzzer 15. As long as the tension sensor 39 receives a signal, the buzzer 15 sounds an alarm or the display screen displays a number, which proves that there is sediment in the solution and the solution needs to be filtered again. Finally, the rotating rod 35 is swung in one direction, the opening of the taking ring 36 faces the non-woven fabric 23, and the sediment falls onto the non-woven fabric 23.

[0031] The recycling component includes an adhesive 40 movably arranged in the verification box, a plurality of winding ropes 42, and a winding component for winding the adhesive 40. The adhesive 40 is movably arranged under the non-woven fabric 23. When the non-woven fabric 23 is filtered, the winding rope 42 is located under the non-woven fabric 23. The winding component includes two winding rollers 41 and two winding motors. The plurality of winding ropes 42 are arranged at intervals from the plurality of adhesives 40. The adhesive 40 adopts the adhesive tape in the prior art, and the adhesive tape is sticky so as not to face the non-woven fabric 23. The winding roller 41 is rotatably arranged in the verification box, and the verification box is provided with a winding cavity, and the winding cavity is provided with a winding Winding groove. In this embodiment, a control panel can be further provided at the position of the winding groove. The control panel slides on the inner wall of the winding cavity. The sliding of the control panel is realized by an electric push rod. The control panel blocks the winding groove to prevent the solution from entering the winding cavity. The winding ropes 42 at both ends are respectively fixedly connected to the outer peripheral walls of the two winding rollers 41. When the non-woven fabric 23 starts to filter and shake, the winding roller is located in the verification box. When the precipitation detection of the non-woven fabric 23 is completed, the adhesive 40 is pulled to the bottom of the non-woven fabric 23, and the frame 22 is rotated. The precipitation in the non-woven fabric 23 falls onto the adhesive 40, thereby completing the collection effect of the precipitation.

[0032] The implementation principle of a probiotic honey dew and its production process and application in the embodiment of the present application is as follows: after the sampling rack 2 drives the sampling tube 3 to the specified position, the first solenoid valve 4 is opened at this time, and the solution enters the sampling tube 3 from the inlet. As the solution enters the sampling tube 3, the solution also enters the identification cavity 12 at the same time, and the floating plate 13 begins to float in the floating cavity. As the liquid level in the sampling tube 3 continues to rise to the specified liquid level, the floating plate 13 also floats to the highest position. At this time, the lowest surface of the floating plate 13 is at the same horizontal plane as the liquid level of the sampling tube 3, and the top of the floating plate 13 just contacts the proximity switch 14, and the proximity switch 14 triggers the buzzer 15 to start the alarm. Of course, the proximity switch 14 and the first solenoid valve 4 can also be controlled and connected by different PLC controllers. When the floating plate 13 contacts the proximity switch 14, the buzzer 15 starts to alarm and the first solenoid valve 4 is closed, and the sampling tube 3 is drawn out of the solution; When the sampling tube 3 moves to the corresponding position, the first electromagnet 8 is controlled to move by the reciprocating member 9. The reciprocating member 9 can be an electric push rod. Therefore, the first electromagnet drives the reciprocating rod 7 to continue to move downward, and the sampling tube 3 continues to compress the first spring 10. After the first spring 10 is compressed, the first electromagnet 8 is powered off. Under the elastic force of the first spring 10, the sampling tube 3 starts to move upward, and the solution in the sampling tube 3 vibrates. After reciprocating for many times, the solution in the sampling tube 3 moves violently, and the precipitation inside is evenly distributed and moves violently in the solution. It is irradiated by the light source board 18, and photographed by a general camera 19. The staff watches the situation in the solution displayed on the screen. If the precipitation is distributed more, the movement of the precipitation in the solution can be easily found at this time, and there is no need for a subsequent review agency to review it. However, if the precipitation is not distributed much, it is judged that there may be a problem, so a review agency is required to review it. When the non-woven fabric 23 needs to be filtered, the non-woven fabric 23 is straightened, that is, the shaking plate 26 is fitted with one end of the frame 22, the second solenoid valve 24 is opened, the non-woven fabric 23 filters the solution, and the limit electromagnet adsorbs the connecting rod 28. When the filtration is completed, the limit electromagnet releases the connecting rod 28, and at this time, the shaking motor 33 rotates, and the raised part of the cam 31 moves the connecting block 27 toward the outer foundation of the protective box 29. At this time, the second spring 32 is in a stretched state. If the cam 31 is separated from the connecting block 27, under the elastic force of the second spring 32, the shaking plate 26 drives the non-woven fabric 23 to move quickly toward the end of the frame 22. At this time, the non-woven fabric 23 shakes the sediment above it upward, and the sediment located on the side of the non-woven fabric 23 gradually gathers toward the bottom of the non-woven fabric 23 as the non-woven fabric 23 naturally droops, thereby achieving the effect of accelerating sedimentation drainage and sediment collection; When the non-woven fabric 23 shakes off the sediment, the control check motor drives the rotating rod 35 to rotate, and the rotating rod 35 drives the picking ring 36 to move toward the direction of the non-woven fabric 23. The opening end of the picking ring 36 moves to the sediment first, and as the rotating rod 35 continues to rotate, the picking ring 36 takes the sediment from the non-woven fabric 23, and the sediment falls on the checking sheet 37. If there is sediment on the checking sheet 37, the tension sensor 39 monitors the change in tension at the first time. Here, the tension sensor 39 can be electrically connected to the display screen or the buzzer 15. As long as the tension sensor 39 receives a signal, the buzzer 15 sounds an alarm or the display screen displays a number, which proves that there is sediment in the solution and the solution needs to be filtered again. Finally, the rotating rod 35 is swung in another direction, and the opening of the picking ring 36 faces the non-woven fabric 23, and the sediment falls on the non-woven fabric 23. Embodiment 2

[0033] The present application embodiment discloses a probiotic honey dew. Figure 1A probiotic honey dew includes the following components: honey: 60% 96%, probiotics: 1% 5%; small molecule peptides: 0.5% 5%; prune juice: 1% 10% grapefruit juice: 1% 10%; hyaluronic acid: 0.5% 10%; among them, honey 74%, probiotics 5%, small molecule peptides 0.5%, prune juice 10%, grapefruit juice 10%, and hyaluronic acid 0.5% can also be selected. The probiotics are composed of multiple strains of Bifidobacterium lactis HN019, Bifidobacterium lactis Bi 07, Lactobacillus acidophilus NCFM, Bifidobacterium animalis Bb 12, Lactobacillus rhamnosus LGG, and Lactobacillus rhamnosus HN001. By adding Bifidobacterium lactis HN019, it can regulate the intestinal flora, improve diarrhea or constipation caused by intestinal dysfunction, and have anti-allergic and anti-tumor effects, as well as improve immunity; by adding Bifidobacterium lactis Bi 07, it can not only treat constipation, but also have immune and protective effects on the intestines, and can also regulate the balance of intestinal flora, and can also improve the levels of serum and specific antibodies; Lactobacillus acidophilus NCFM prevents other harmful bacteria from multiplying in the intestines, and can prevent and treat human intestinal diseases; Animal Bifidobacterium Bb 12 can enhance immunity, regulate intestinal flora, laxative, and promote digestion; Lactobacillus rhamnosus LGG and Lactobacillus rhamnosus HN001 can not only prevent the reproduction of harmful bacteria, but also promote the growth of beneficial bacteria, such as Bacteroides, Clostridium and Bifidobacterium.

[0034] It also has the following effects: (1) Improve constipation: Promote intestinal motility: Probiotic honey contains a certain amount of probiotics, which can promote gastrointestinal motility, thereby helping to relieve constipation symptoms. Honey itself also has a good laxative effect, which can further promote defecation. Quick effect: Generally speaking, after using probiotic honey, most people can defecate within an hour. For patients with severe constipation, they may start to defecate after 2 to 3 hours. (2) Improve body immunity: Rich in nutrients: Probiotic honey contains rich nutrients such as protein, vitamins, glucose, and trace elements such as calcium, potassium, and magnesium. These ingredients can provide the body with necessary nutritional supplements. Enhance immunity: By providing the body with sufficient nutrition, probiotic honey helps to enhance the body's immunity and improve the body's ability to resist diseases. (3) Regulate intestinal flora: The role of beneficial bacteria: The probiotics in probiotic honey can colonize and reproduce in the intestines, forming a competitive relationship with harmful bacteria, thereby regulating the balance of intestinal flora. Promote nutrient absorption: Balanced intestinal flora helps promote the digestion and absorption of nutrients and maintain intestinal health. (4) Other effects: Aid digestion: Probiotic honey dew also has the function of aiding digestion and can relieve symptoms such as indigestion. Safe and reliable: Especially for special groups such as pregnant women and children, probiotic honey dew uses natural honey and active probiotics as the main raw materials, does not contain chemical additives, and is therefore safer and more reliable. Embodiment 3

[0035] The present application example discloses an application of the probiotic honey solution obtained by the preparation method of Example 1 in the clinical treatment of constipation.

[0036] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A production process of probiotic honey dew, characterized in that: The steps include: S1. Prepare materials: honey, probiotics and other auxiliary materials need to be prepared according to the composition ratio; S2, pretreatment: heating, dissolving and filtering the raw materials to ensure the purity and uniformity of the raw materials; S3, mixing and stirring: putting the pretreated raw materials into a mixing device, stirring and mixing them fully to form a stable mixture; S4, filling: injecting the evenly mixed probiotic honey dew into a pre-prepared container through a filling device; During the stirring process of step S3, the mixture needs to be randomly inspected at any time to see if there is any precipitate; wherein the precipitate is initially inspected and re-inspected to improve the purity of the mixture; The sampling step uses a detection device to detect whether there is sediment, and the detection device includes a sampling mechanism, a viewing mechanism for initial inspection of the sediment, and a review mechanism for re-inspecting the sediment that cannot be detected by the viewing mechanism; The sampling mechanism comprises a support (1) arranged on the mixing device, a sampling frame (2) lifted and arranged on the support (1), a plurality of sampling tubes (3) elastically arranged on the support (1), a plurality of first electromagnetic valves (4), an identification component for identifying the liquid level in the sampling tube (3), and a reciprocating component for controlling the reciprocating motion of the sampling tube (3); the sampling tube (3) is provided with a water inlet (5), and the first electromagnetic valve (4) is arranged at the water inlet (5).

2. The probiotic honey dew and its production process and application according to claim 1, characterized in that: The reciprocating assembly comprises a reciprocating box (6), a reciprocating rod (7), a first electromagnet (8) and a reciprocating member (9) for controlling the reciprocating motion of the first electromagnet (8); the bottom end of the sampling tube (3) is fixedly connected to a first spring (10); the sampling box is provided with a reciprocating hole for the reciprocating rod (7) to pass through; the first spring (10) is sleeved outside the reciprocating rod (7) and the bottom end of the spring is fixedly connected to the sampling box.

3. The probiotic honey dew and its production process and application according to claim 2, characterized in that: The identification component comprises an identification box (11) arranged on the side wall of the sampling tube (3), an identification cavity (12) arranged in the identification box (11), a floating plate (13) floatingly arranged in the identification cavity (12), a proximity switch (14) and a water inlet (16) arranged on the top of the identification box (11); the bottom of the final stop position of the floating plate (13) is in the same horizontal plane as the set liquid level in the sampling tube (3); one end of the water inlet (16) is connected to the sampling tube (3) and the other end is connected to the identification cavity (12); and the proximity switch (14) is electrically connected to a buzzer (15).

4. The probiotic honey dew and its production process and application according to claim 3, characterized in that: The viewing mechanism comprises a viewing cover (17), a light source plate (18) slidably arranged in the viewing cover (17), and a plurality of cameras (19); the viewing cover (17) is fixed on the bracket (1); the viewing cover (17) covers the plurality of sampling tubes (3); transparent plates (20) are arranged on two opposite sides of the sampling tubes (3); the light source plate (18) and the cameras (19) are respectively opposite to the two transparent plates (20).

5. The probiotic honey dew and its production process and application according to claim 3, characterized in that: The review mechanism comprises a review box (21), a frame (22), a non-woven fabric (23), a shaking component for shaking the non-woven fabric (23), a checking mechanism for reviewing the sediment, and a recovery component for recovering the sediment. One end of the review box (21) is connected to the bottom side wall of the sampling tube (3), and a second solenoid valve (24) is provided at the connection position. The frame (22) is rotatably arranged in the review box (21) and the review box (21) is adapted to the frame (22). A rotating motor (25) for controlling the rotation of the frame (22) is provided on the inner wall of the review box (21). The non-woven fabric (23) is elastically arranged in the frame (22).

6. The probiotic honey dew and its production process and application according to claim 5, characterized in that: The shaking assembly includes a shaking plate (26), a connecting block (27), a protective box (29), a connecting rod (28), a protrusion (30), a cam (31), a second spring (32) and a shaking motor (33) for controlling the rotation of the cam (31); one end of the non-woven fabric (23) is fixedly connected to the frame (22); the shaking plate (26) is connected to the other end of the non-woven fabric (23); the shaking plate (26) is slidably adapted in the frame (22); the connecting block (27) is fixedly connected to the upper end of the shaking plate (26); the protective box (29) is arranged on the frame (22) and the protective box (29) is provided with a connecting member for the shaking plate (26); The rod (28) passes through a through hole (34), one end of the connecting rod (28) is connected to the connecting block (27), the other end of the connecting rod (28) slides in the protective box (29), the protrusion (30) is fixedly connected to the end of the connecting rod (28) located in the protective box (29), the cam (31) is rotatably connected to the protective box (29), the raised portion of the cam (31) abuts against the outer wall of the connecting block (27), the end of the connecting rod (28) located in the protective box (29) is also fixedly connected to the second spring (32), and the other end of the second spring (32) is fixedly connected to the inner wall of the protective box (29).

7. The probiotic honey dew and its production process and application according to claim 6, characterized in that: The checking component comprises a rotating rod (35) rotatably arranged at the top end of the checking box (21), a checking motor for controlling the rotation of the rotating rod (35), a picking ring (36) fixed at the end of the rotating rod (35), a checking piece (37), a plurality of checking ropes (38) and a tension sensor (39), one end of the picking ring (36) is open, the checking piece (37) is fixed at the end of the picking piece in the rotation direction, a plurality of checking holes are arranged in the peripheral wall of the picking ring (36), one end of the checking rope (38) is fixedly connected to one end of the checking hole, and the other end is fixedly connected to the peripheral wall of the checking piece (37), and the plurality of checking ropes (38) are evenly spaced and distributed on the peripheral wall of the checking piece (37), the original area of ​​the checking piece (37) is larger than the inner diameter of the picking ring (36), and the checking piece (37) is in contact with the end of the picking ring (36).

8. The probiotic honey dew and its production process and application according to claim 6, characterized in that: The recycling component comprises an adhesive (40) movably arranged in the checking box, a plurality of winding ropes (42) and a winding component for winding the adhesive (40), wherein the adhesive (40) is movably arranged below the non-woven fabric (23), and the winding rope (42) is located below the non-woven fabric (23) when the non-woven fabric (23) is filtered.

9. A probiotic honey dew, obtained by the production process of the probiotic honey dew according to any one of claims 1 to 8, characterized in that: The invention comprises the following components: 74% honey, 5% probiotics, 0.5% small molecule peptides, 10% prune juice, 10% grapefruit juice and 0.5% hyaluronic acid. The probiotics are composed of a combination of multiple strains including Bifidobacterium lactis HN019, Bifidobacterium lactis Bi 07, Lactobacillus acidophilus NCFM, Bifidobacterium animalis Bb 12, Lactobacillus rhamnosus LGG and Lactobacillus rhamnosus HN001.

10. A production process of the probiotic honey extract according to any one of claims 1 to 8 or use of the probiotic honey extract according to claim 9 in the clinical treatment of constipation.

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