Composition for preventing and treating bacterial diseases of crops

Abstract

The invention relates to the technical field of pesticide production, and discloses a composition for preventing and treating bacterial diseases of crops. The composition is prepared from carboxin and fluazinam, the mass ratio of the fluazinam to the carboxin is (1%-50%): (5%-90%). The composition provided by the invention has relatively high activity on peach tree bacterial shothole, potato scab powder, potato black shank, solanaceae bacterial wilt, citrus canker, ginger blast, solanaceae canker, cucurbitaceae bacterial angular leaf spot, rice streak, rice bacterial leaf blight, pear fire blight, mango angular leaf spot and mango bacterial black spot; the composition has a remarkable synergistic effect and is superior to a single agent in the aspects of fast-acting property and persistence, and the use dosage and cost of the pesticide are reduced.

Description

Technical Field

[0001] The invention relates to the technical field of pesticide production, and in particular to a composition for preventing and controlling bacterial diseases of crops. Background Art

[0002] Bacterial diseases are characterized by rapid spread, serious harm, and difficulty in prevention and control. The current mainstream prevention and control agents for bacterial diseases include copper preparations, microbial preparations, etc.

[0003] Copper preparations such as copper hydroxide and Bordeaux mixture have the characteristics of slow resistance development, broad spectrum, and high efficiency, but copper preparations are sensitive to crops such as peach and plum trees and need to be avoided during the flowering and young fruiting stages. Microbial agents represented by kasugamycin and zhongshengmycin have the characteristics of low residue and no pollution. They are environmentally friendly green biological pesticides and are relatively safe for the environment and human body. However, the stability of microbial preparations is poor, and the efficacy of the drug is easily affected by environmental factors. At the same time, the price is relatively expensive.

[0004] Therefore, the prior art still needs to be improved and developed. Summary of the invention

[0005] In view of the above-mentioned deficiencies in the prior art, an object of the present invention is to provide a composition and system for preventing and controlling bacterial diseases of crops, aiming to solve the problems of limited application and high cost of existing pesticides for preventing and controlling bacterial diseases of crops.

[0006] The technical solution provided by the present invention is as follows:

[0007] In a first aspect, a composition for preventing and controlling bacterial diseases of crops is provided, wherein the composition comprises carboxin and fluazinam; the mass ratio of fluazinam to carboxin is 1% to 50%: 5% to 90%.

[0008] The following are preferred technical solutions of the present invention, but are not intended to limit the technical solutions provided by the present invention. Through the following preferred technical solutions, the objectives and beneficial effects of the present invention can be better achieved and realized.

[0009] As a preferred technical solution, the composition for preventing and controlling bacterial diseases of crops is formulated into water dispersible granules, suspoemulsions, seed treatment suspensions, wettable powders, dry suspensions, granules, aqueous emulsions, microemulsions, microcapsule suspensions, oil suspensions, emulsifiable concentrates and soluble solutions.

[0010] As a preferred technical solution, the composition for preventing and controlling bacterial diseases of crops, wherein the composition further contains adjuvants required for preparing pesticide formulations, and the adjuvants are selected from one or a mixture of solvents, emulsifiers, wetting agents, stabilizers, dispersants, thickeners, pH regulators, defoamers, antifreeze agents, and fillers.

[0011] As a preferred technical solution, the composition for preventing and controlling bacterial diseases of crops, wherein the bacterial diseases of crops include peach bacterial punchhole disease, potato powdery scab, potato black shank disease, Solanaceae bacterial wilt, citrus canker, ginger blight, Solanaceae canker, cucurbitaceae bacterial angular spot disease, rice leaf streak disease, rice white leaf blight, amylopectin disease, mango angular spot disease, and mango bacterial black spot disease.

[0012] As a preferred technical solution, the composition for preventing and controlling bacterial diseases of crops comprises: bacterial punch hole disease of peach, bacterial wilt of Solanaceae and leaf streak disease of rice.

[0013] In a second aspect, a method for preventing and controlling bacterial diseases of crops is provided, wherein the composition described above is applied to plants and / or their cultivation media.

[0014] As a preferred technical solution, the method for preventing and controlling bacterial diseases of crops, wherein the subjecting the composition of claim 1 to the plant and / or its cultivation medium, specifically comprises: applying the composition of claim 1 to the plant or its cultivation medium in an agronomically effective and substantially non-phytotoxic application amount by seed treatment, foliar application, or stem application.

[0015] As a preferred technical solution, the method for preventing and controlling bacterial diseases of crops, wherein the subjecting the composition according to claim 1 to the plant and / or its cultivation medium, specifically comprises: applying the composition according to claim 1 to the plant or its cultivation medium in an agronomically effective and substantially non-phytotoxic application amount by soaking, dripping, pouring, spraying, dusting or smoking.

[0016] In a third aspect, a method for preventing and controlling bacterial diseases of crops is provided, wherein the above-mentioned composition is applied to plant pathogenic bacteria and / or their environment.

[0017] Beneficial effects: Compared with the prior art, the present invention has a significant synergistic effect by using carboxin and fluazinam together, which improves the control effect of pathogens compared with using them alone. Since carboxin and fluazinam have different mechanisms of action, using them together can delay the development of bacterial resistance, reduce the amount of pesticides used, reduce the cost of use and be environmentally friendly. DETAILED DESCRIPTION

[0018] The present invention provides a composition for preventing and controlling bacterial diseases of crops. To make the purpose, technical scheme and effect of the present invention clearer and more specific, the present invention is further described in detail below. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0019] In addition, the characteristics, operations or features described in the specification can be combined in any appropriate manner to form various embodiments. At the same time, each step or action in the method description can also be replaced or adjusted in order in a manner that is obvious to those skilled in the art. Therefore, the various sequences in the specification are only for the purpose of clearly describing a certain embodiment and do not mean that it is a necessary sequence, unless otherwise specified that a certain sequence must be followed. The serial numbers themselves, such as "first", "second", etc., compiled for the components herein are only used to distinguish the objects described and do not have any order or technical meaning. The instruments and reagents used are all commercially available products.

[0020] The inventors have found that a drug has a good disease prevention effect in the early stage, but as the number of uses increases, the dosage gradually increases, and the efficacy is slightly improved, and sometimes even completely loses its disease prevention effect. The main reason is that the pathogen population has changed, that is, some pathogens have acquired drug-resistant plasmids through mutation and developed drug resistance, and gradually formed dominant populations in natural selection, resulting in reduced efficacy of fungicides. The combined application of pesticides is an important means to delay the development of drug resistance in pathogens, and it is also an effective method to reduce the amount of pesticides used. The scientific nature of the combined application of fungicides depends not only on the control targets and the mechanism of action, but also on the nature of the combined action after the agents are mixed. However, there are many constraints in the development of a high-efficiency fungicide composition with complementary effects and significant synergistic properties, and the success rate is extremely low.

[0021] Carboxin is a heterocyclic fungicide with systemic action. It is currently mainly used for cereal smut, wheat rust, Verticillium wilt, etc. Fluazinam belongs to the dinitroaniline fungicide and is a broad-spectrum and highly effective protective fungicide. It is mainly used for pathogenic fungal diseases such as Alternaria, Phytophthora, Monoparacephala, Sclerotinia and Venturia, and is also used for fruit tree mite control.

[0022] The inventors of the present invention compounded carboxin and fluazinam to form a composition, and found through indoor toxicity test that fluazinam has high activity against Pseudomonas, the pathogenic bacteria of citrus canker, Ralstonia solani, the pathogenic bacteria of solanaceous bacterial wilt, and Xanthomonas, the pathogenic bacteria of rice bacterial leaf streak, etc.

[0023] By mixing carboxin and fluazinam in a certain proportion, preparation products with different contents and types are prepared. In field trials, the preparation products have good prevention and control effects on leaf and root diseases of crops such as peach bacterial perforation disease, potato powdery scab, potato black shank, Solanaceae bacterial wilt, citrus canker, ginger blight, Solanaceae canker, cucurbitaceae bacterial angular spot, rice streak disease, rice white leaf blight, amylovora, mango angular spot disease, and mango bacterial black spot. The prevention effect of the combination is better than that of fluazinam and carboxin alone, and is also better than the common bacterial disease control agents on the market.

[0024] The composition for preventing and controlling bacterial diseases of crops provided by the present invention is further explained below through specific preparation examples.

[0025] Example 1

[0026] Carboxin + fluazifop (1:1) 40% SC

[0027] Put 20% of carboxin and 20% of fluazinam into the sand mill, start grinding, take samples at regular intervals to observe the fineness, until the pre-grind is about 200 mesh. Put the pre-grind and dispersant styrene acrylic polymer 1.5% + attapulgite 2%; propylene glycol 5%; polyether polyol Geowet HR 0.15% into the sand mill and high-speed shear process. During the grinding process, add 0.15% of defoaming agent silicone; water is added to 100%, and the final product has a particle size D90 below 15 microns. If the sampling test is qualified, it is a 40% suspension.

[0028] Example 2

[0029] Carboxin + Fluazifop (2:1) 60% WG

[0030] In a stirring kettle, 40% of carboxin, 20% of fluazinam, 6% of sodium lignin sulfonate, 4% of alkylnaphthalene sulfonate formaldehyde condensate, 1.5% of sodium ester sulfonate and other materials are added in sequence, and kaolin is added to 100%. The stirring is turned on and stirred for 1-2 hours until it is completely stirred and uniform. The air flow mill is turned on for crushing, and the crushed material is stirred and mixed for another 1-2 hours. After sampling and analysis are qualified, the material is discharged and the material is transferred to a fluidized bed for granulation. After sampling and testing are qualified, 60% water-dispersible granules are obtained.

[0031] Example 3

[0032] Carboxin + fluazifop (3:1) 30% SE

[0033] 30% of carboxin, 10% of fluazinam, 1.0% of TERSPERSE 4896, 3.5% of TERGITOL XD, 2.0% of propylene glycol, and 0.5% of defoamer are supplemented to 100% with ionized water, mixed and stirred evenly, and continuously sand-milled to obtain a 40% suspension of fluazinam + carboxin. 15% of emulsifier Atlox4838B is dissolved in esterified soybean oil and stirred evenly to obtain an oil phase; 2% of Tween 80 is added to the prepared 40% fluazinam + carboxin suspension and stirred evenly to obtain an aqueous phase; the prepared oil phase is poured into the aqueous phase and high-speed homogenization is turned on to form a stable suspension emulsion. Stirring is turned on, 0.5% of kason is added to the above suspension emulsion, and the suspension is supplemented to 100% with an aqueous solution of xanthan gum, and stirred evenly to obtain a 30% suspension emulsion SE.

[0034] Example 4

[0035] Carboxin + Fluazifop (4:1) 75% WP

[0036] In a stirring kettle, 60% of carboxin, 15% of fluazinam, 2.8% of sodium lignin sulfonate, 1.5% of sodium dodecyl sulfate, 6% of sodium methylene dinaphthalene sulfonate and other materials are added in sequence, and kaolin is added to 100%. Stir for 1-2 hours until it is completely uniform, turn on the air flow mill to grind, and stir and mix the ground material for another 1-2 hours. If the sample is qualified for inspection, 75% wettable powder is obtained.

[0037] Example 5

[0038] Carboxin + Fluazifop (5:1) 30% FS

[0039] In a shearing kettle, add 25% of carboxin, 5% of fluazinam, 2.5% of tristyrylphenol polyoxyethylene ether phosphate, 2.0% of polyethylene oxide polypropylene oxide monobutyl ether, 1.0% of sodium naphthalenesulfonate formaldehyde condensate, 0.1% of polysiloxane, 1.5% of xanthan gum, 5% of propylene glycol, 5% of pigment red, 0.8% of polyvinyl pyrrolidone and other materials in sequence, add water to 100%, and pass the test after 2 high-speed shearing and 2 sand grinding.

[0040] Indoor bio-test example:

[0041] Using the turbidity method, on the basis of the preliminary experiment, the initial test concentrations of fluazinam and carboxin were adjusted; the antibacterial rates of the mixtures against different pathogens were tested at different ratios of fluazinam: carboxin 1:2, 1:3, and 1:5. The test results are shown in Tables 1 and 2:

[0042] Table 1 Inhibition rate of fluazinam and carboxin against bacterial perforation pathogen of peach, Ralstonia solanacearum and bacterial leaf streak pathogen of rice

[0043]

[0044]

[0045] Table 2 Combined toxicity test of fluazinam and carboxin against the pathogen of peach bacterial puncture disease (Xanthomonas napus)

[0046]

[0047]

[0048] The biological activity is determined by foliar spraying or root irrigation. The first application of the drug is when the disease first occurs. The drug is applied 2-3 times with an interval of 7-10 days. The prevention effect is investigated 7-15 days after the last application of the drug.

[0049] Bioassay Example 1 Carboxin + Fluazinam 40% SC:

[0050] Table 3 Field efficacy results of carboxin + fluazinam (1:1) 40% SC on citrus canker

[0051] Chemical treatment Effectiveness 15 days after the last dose Carboxin + Fluazifop 40% SC 2000 times 80.12％ Carboxin + Fluazifop 40% SC 1500 times 87.30％ Carboxin + Fluazifop 40% SC 1000 times 92.97％ 12% Carboxin WP 400 times 57.80％ 50% Fluazinam SC 2500x 60.19％

[0052] Bioassay Example 2 Carboxin + Fluazinam 60% WG

[0053] Table 4 Field efficacy results of carboxin + fluazinam (2:1) 60% WG on mango angular leaf spot

[0054] Chemical treatment Effectiveness 15 days after the last dose Carboxin + Fluazifop 50% WG 2500 times dilution 81.09％ Carboxin + Fluazifop 50% WG 2000 times dilution 85.64％ Carboxin + Fluazifop 50% WG 1500 times dilution 88.01％ 12% Carboxin WP 400 times dilution 48.97％ 50% Fluazinam SC 2500 times dilution 58.90％

[0055] Bioassay Example 3 Carboxin + Fluazinam 30% Suspoemulsion SE

[0056] Table 5 Field efficacy test results of carboxin + fluazinam (3:1) against potato powdery scab

[0057]

[0058] Bioassay Example 4 (Carboxin + Fluazinam 75% Wettable Powder WP)

[0059] Table 6 Field efficacy test results of carboxin + fluazinam (4:1) against rice bacterial leaf blight

[0060] Chemical treatment Effectiveness 7 days after the last dose Carboxin + Fluazifop 75% WP 2500 times 80.37％ Carboxin + Fluazifop 75% WP 2000 times 85.10％ Carboxin + Fluazifop 75% WP 1500 times 86.91％ 12% Carboxin WP 400 times dilution 60.78％ 50% Fluazinam SC 5000 times dilution 68.45％

[0061] Bioassay Example 5 Carboxin + Fluazinam 30% FS

[0062] Table 7 Field efficacy test results of carboxin + fluazinam (5:1) against ginger blight of ginger

[0063] Chemical treatment (seed dressing) Effectiveness 15 days after the last dose Carboxin + Fluazifop 30% FS 1500 times 73.40％ Carboxin + Fluazifop 30% FS 1250 times 83.18％ Carboxin + Fluazifop 30% FS 1000 times 89.90％ 12% Carboxin WP 400 times dilution 52.51％ 50% Fluazinam SC 5000 times dilution 68.02％

[0064] Bioassay Example 6

[0065] Table 8 Field efficacy test results of fluazinam + carboxin combination against tomato bacterial wilt

[0066]

[0067] Bioassay Example 7

[0068] Table 9 Field efficacy test results of fluazinam + carboxin combination on cucumber angular leaf spot

[0069] Chemical treatment Effectiveness 7 days after the last dose Effectiveness 15 days after the last dose 40% fluazinam + carboxin SC 1500 times 84.90％ 94.17％ 50% Fluazinam + Carboxin WG 2000 times dilution 82.09％ 88.33％ 30% fluazinam + carboxin SE 1000 times 81.04％ 86.90％ 20% Thiazole Zinc SC 500 times dilution 69.06％ 71.45％

[0070] Bioassay Example 8

[0071] Table 10 Field efficacy test results of fluazinam + carboxin combination against potato black leg

[0072] Chemical treatment Effectiveness 7 days after the last dose Effectiveness 15 days after the last dose 40% fluazinam + carboxin SC 1500 times 88.58％ 93.94％ 50% Fluazinam + Carboxin WG 2000 times dilution 84.37％ 86.09％ 30% fluazinam + carboxin SE 1000 times 84.78％ 88.10％ 20% Thiazole Zinc SC 500 times dilution 65.11％ 73.78％

[0073] Bioassay Example 9

[0074] Table 11 Field efficacy test results of fluazinam + carboxin combination on mango bacterial black spot

[0075]

[0076]

[0077] Bioassay Example 10

[0078] Table 12 Field efficacy test results of fluazinam + carboxin combination on peach bacterial punching disease

[0079] Chemical treatment Effectiveness 7 days after the last dose Effectiveness 15 days after the last dose 40% fluazinam + carboxin SC 1500 times 78.50％ 83.12％ 50% Fluazinam + Carboxin WG 2000 times dilution 80.05％ 82.17％ 30% fluazinam + carboxin SE 1000 times 82.70％ 85.53％ 20% Thiazole Zinc SC 500 times dilution 57.13％ 62.09％

[0080] The data of bioassay examples 1-5 show that when carboxin and fluazinam are prepared into different dosage forms and in different ratios, they have significant preventive effects on citrus canker, mango angular spot, potato powdery scab, rice bacterial leaf blight, ginger wilt, etc.; the preventive effect of the combination of carboxin and fluazinam is significantly better than the control effect of either alone.

[0081] Data from Examples 6-10 of the bioassay show that the carboxin plus fluazinam combination has significant preventive effects on tomato bacterial wilt, cucumber angular spot, potato black shank, mango bacterial black spot, and peach bacterial punching disease under different dosage forms and different ratios; the preventive effect of the combination is better than the commonly used control agents on the market. The combination is safer than inorganic copper preparations for sensitive crops such as melons, peaches, and plums, and has a wider application time range; compared with other bacterial control agents, the combination has higher and more stable preventive effects on the tested bacterial diseases, and has broad application prospects and economic value in agricultural production.

[0082] It should be understood that the application of the present invention is not limited to the above examples. For ordinary technicians in this field, improvements or changes can be made based on the above description. All these improvements and changes should fall within the scope of protection of the claims attached to the present invention.

Claims

1. A composition for preventing and controlling bacterial diseases of crops, characterized in that: The composition comprises carboxin and fluazinam; the mass ratio of fluazinam to carboxin is 1% to 50%: 5% to 90%.

2. The composition for preventing and controlling bacterial diseases of crops according to claim 1, characterized in that: The composition is formulated into water dispersible granules, suspoemulsions, seed treatment suspensions, wettable powders, dry suspensions, granules, aqueous emulsions, microemulsions, microcapsule suspensions, oil suspensions, emulsifiable concentrates and soluble solutions.

3. The composition for preventing and controlling bacterial diseases of crops according to claim 1, characterized in that: The composition also contains auxiliary agents required for preparing pesticide preparations, and the auxiliary agents are selected from one or a mixture of solvents, emulsifiers, wetting agents, stabilizers, dispersants, thickeners, pH regulators, defoamers, antifreeze agents, and fillers.

4. The composition for preventing and controlling bacterial diseases of crops according to claim 1, characterized in that: The bacterial diseases of crops include bacterial punchhole of peach, pink scab of potato, black shank of potato, bacterial wilt of Solanaceae, canker of citrus, ginger blight, canker of Solanaceae, bacterial angular spot of Cucurbitaceae, leaf streak of rice, bacterial leaf blight of rice, fire blight of amylopectin, angular spot of mango, and bacterial black spot of mango.

5. The composition for preventing and controlling bacterial diseases of crops according to claim 4, characterized in that: The bacterial diseases of crops include peach bacterial punch hole, solanaceae bacterial wilt and rice leaf streak disease.

6. A method for preventing and controlling bacterial diseases of crops, characterized in that: The composition according to claim 1 is applied to plants and / or their cultivation media.

7. The method for preventing and controlling bacterial diseases of crops according to claim 6, characterized in that: The method of applying the composition of claim 1 to plants and / or their cultivation media specifically includes: applying the composition of claim 1 to plants or their cultivation media in an agronomically effective and substantially non-phytotoxic application amount by seed treatment, foliar application, or stem application.

8. The method for preventing and controlling bacterial diseases of crops according to claim 6, characterized in that: The method of applying the composition of claim 1 to plants and / or their cultivation media specifically includes: applying the composition of claim 1 to plants or their cultivation media in an agronomically effective and substantially non-phytotoxic application amount by soaking, dripping, pouring, spraying, dusting or smoking.

9. A method for preventing and controlling bacterial diseases of crops, characterized in that: The composition according to claim 1 is applied to plant pathogenic bacteria and / or their environment.

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