Variable-caliber catheter-sheath integrated thrombus aspiration catheter with intra-catheter thrombus breaking function

Abstract

The invention discloses a variable-caliber catheter-sheath integrated thrombus aspiration catheter with an intra-catheter thrombus breaking function, and relates to the technical field of thrombus treatment medical catheters.The catheter-sheath integrated thrombus aspiration catheter comprises a guiding catheter and an aspiration pipe, the aspiration pipe is inserted into the guiding catheter in a sliding mode, and the catheter-sheath integrated thrombus aspiration catheter further comprises a multi-stage adjustment aspiration opening mechanism, a locking mechanism and a thrombus breaking mechanism; and the suction pipe is used for driving the multi-stage adjustment suction port mechanism to retract into the guide pipe or expand outwards from the guide pipe step by step. The multi-stage suction port adjusting mechanism connected with the end part can be driven by the suction pipe to extend out of the guide pipe, and is expanded step by step to reach the caliber with the corresponding size, and the multi-stage suction port adjusting mechanism is composed of the adjusting and scaling assembly, the supporting section metal wire and the covering film, so that a suction port with a larger caliber is conveniently defined; the thrombus can be conveniently and completely sucked and guided into the suction tube, an expander is not needed, operation of a doctor is reduced, and the situation that large thrombus is broken before being sucked into the tube and escapes to a far-end blood vessel to cause blockage can be avoided.

Description

Technical Field

[0001] The invention relates to the technical field of thrombus treatment medical catheters, and in particular to a variable-caliber tube-sheath integrated thrombus aspiration catheter with an in-tube thrombus crushing function. Background Art

[0002] Acute pulmonary embolism is one of the three most common fatal cardiovascular diseases, with pulmonary circulation and respiratory dysfunction as the main clinical manifestations. Acute pulmonary embolism mainly originates from the inferior vena cava, superior vena cava or right heart cavity, and interventional treatment can be used to remove the thrombus blocking the pulmonary artery.

[0003] Existing interventional treatments include: catheter fragmentation, thrombus aspiration and stent thrombectomy. Among them, thrombus aspiration has a good clinical effect. Generally, the aspiration catheter is inserted into the blood vessel through a puncture operation to reach the location of the thrombus, and then the thrombus is aspirated out by a negative pressure device such as a suction pump connected to the aspiration catheter.

[0004] However, the existing suction catheter devices for thrombus treatment have the following shortcomings: the existing suction catheters are all fixed in size and cannot be adjusted in diameter. When faced with some larger thrombi, it is impossible to accommodate the thrombi at one time to complete the suction, and the suction efficiency is low. It is also easy for part of the thrombi to be cut into pieces by the side wall of the tube mouth during the suction process, so that they escape and cause embolism in the distal blood vessels of the pulmonary artery branches. In addition, after large-volume thrombi are sucked into the pipeline, there is a risk of tube blockage, which makes it impossible to effectively complete the suction of thrombi. Although thrombi can also be suctioned by increasing the size of the suction catheter, the increase in the diameter of the catheter makes it inconvenient to directly use a guide wire to introduce it into the lesion site. An expansion sheath needs to be used in conjunction with it, and the expansion sheath is used for integrated introduction. This not only prolongs the operation time, but also increases the risk of blood leakage at the handheld end of the catheter. Summary of the invention

[0005] The purpose of the present invention is to provide a variable-caliber tube-sheath integrated thrombus aspiration catheter with an in-tube thrombus-breaking function, so as to solve the technical problem that the existing thrombus aspiration catheters in the prior art are all fixed in size and cannot be adjusted in diameter, making it inconvenient to complete large-volume thrombus aspiration surgery.

[0006] The technical problem to be solved by the present invention can be achieved by the following technical solutions:

[0007] A variable-caliber tube-sheath integrated thrombus aspiration catheter with an in-tube thrombus-breaking function comprises a guide tube and an aspiration tube, wherein the aspiration tube is slidably inserted into the guide tube, and further comprises:

[0008] A multi-stage adjustable suction port mechanism and a locking mechanism; the multi-stage adjustable suction port mechanism is cooperatively arranged at one end of a suction pipe, the suction pipe is used to drive the multi-stage adjustable suction port mechanism to retract into the guide pipe or to expand outward from the guide pipe step by step, the locking mechanism is cooperatively arranged between the suction pipe and the guide pipe, and the locking mechanism is used to lock the relative position of the suction pipe and the guide pipe;

[0009] As a further solution of the present invention: the multi-stage adjustable suction port mechanism includes an adjustable zoom component, a supporting section metal wire and a coating, and there are multiple adjustable zoom components, each of which includes multiple circumferentially distributed supporting metal structures, and the multiple adjustable zoom components are equidistantly distributed along the axial direction of the suction pipe, and the sizes increase one by one, and adjacent adjustable zoom components are fixedly connected by the supporting section metal wire.

[0010] As a further solution of the present invention: the supporting metal structure is a W-shaped structure.

[0011] As a further solution of the present invention: a silicone ring is fixedly connected to one end of the multi-stage adjustable suction port mechanism away from the suction pipe.

[0012] As a further solution of the present invention: the locking mechanism includes a positioning sleeve and a knob fixing assembly, the positioning sleeve fixing sleeve is arranged on one end of the guide tube, the knob fixing assembly is rotatably arranged on the positioning sleeve, and the knob fixing assembly is used to fix the suction tube.

[0013] As a further solution of the present invention: the knob fixing assembly includes a threaded sleeve, a fixed threaded sleeve, an elastic locking rubber ring and a conical guide sleeve, the fixed threaded sleeve is coaxially fixedly connected to one end of the positioning sleeve, and the suction tube passes through the fixed threaded sleeve, one end of the threaded sleeve is threadedly connected to the fixed threaded sleeve, the elastic locking rubber ring is arranged on the inner side of the other end of the threaded sleeve, and the elastic locking rubber ring is used to hold the outer wall of the suction tube, the conical guide sleeve is arranged between the suction tube and the fixed threaded sleeve, and the conical guide sleeve is fixedly connected to the fixed threaded sleeve.

[0014] As a further solution of the present invention: an end of the guide tube away from the multi-stage adjustable suction port mechanism is fixedly connected with an annular silicone sheet, and the annular silicone sheet wraps the suction tube.

[0015] As a further solution of the present invention, it also includes a thrombus breaking mechanism, which includes a plurality of protruding blades, and the thrombus breaking mechanism relies on the protruding blades to break the thrombus.

[0016] As a further solution of the present invention: the thrombus breaking mechanism is arranged inside the suction tube, and the raised blades of the thrombus breaking mechanism are distributed in a spiral shape along the inner wall of the suction tube.

[0017] As a further solution of the present invention: the thrombus breaking mechanism is arranged at one end of the multi-stage adjustment suction port mechanism close to the suction tube.

[0018] Beneficial effects of the present invention:

[0019] 1. The present invention can drive the multi-stage adjustable suction port mechanism connected to the end to extend out of the guide tube through the sliding of the suction tube relative to the guide tube, and gradually expand to reach a corresponding size of the caliber. The multi-stage adjustable suction port mechanism is composed of an adjustable zoom component, a supporting section of metal wire and a coating, which is convenient for forming a suction port with a larger caliber, so that the thrombus can be completely sucked and guided into the suction tube without the need for a dilator, reducing the doctor's operation, and preventing the larger thrombus from being broken before being sucked into the tube and escaping to the distal blood vessel to cause blockage.

[0020] 2. Since the multi-stage adjustable suction port mechanism of the present invention has a variable diameter function, the multi-stage adjustable suction port mechanism can be received into the guide tube through the suction tube, and the sizes of the suction tube and the guide tube are set smaller, so as to reduce the contact area between the guide tube and the blood vessel during the withdrawal process, thereby reducing the blood vessel damage caused by the friction between the guide tube and the blood vessel wall.

[0021] 3. The present invention provides a thrombus breaking mechanism to break up the thrombus sucked into the multi-stage adjustable suction port mechanism or the suction tube, thereby preventing the thrombus from blocking the tube body and escaping from breaking up, thereby affecting the thrombus suction effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The present invention will be further described below in conjunction with the accompanying drawings.

[0023] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0024] Figure 2 It is a structural schematic diagram of the multi-stage adjustment suction port mechanism in the present invention in an unfolded state;

[0025] Figure 3 It is a cross-sectional schematic diagram of the multi-stage adjustable suction port mechanism of the present invention when it is retracted in the guide tube;

[0026] Figure 4 It is a schematic diagram of the structure in which the thrombus breaking mechanism is arranged in the suction tube in the present invention;

[0027] Figure 5 It is a structural schematic diagram of the thrombus breaking mechanism in the present invention arranged in the multi-stage adjustment suction port mechanism.

[0028] Figure 6 It is a schematic cross-sectional structure diagram of the suction tube and the guide tube in the present invention;

[0029] Figure 7 yes Figure 6 Schematic diagram of the enlarged structure at A in the middle

[0030] In the figure: 1. Multi-stage adjustment of suction port mechanism; 12. Adjustment and scaling assembly; 13. Support section metal wire; 14. Silicone ring; 15. Coating; 2. Guide tube; 3. Locking mechanism; 31. Positioning sleeve; 32. Annular silicone sheet; 33. Threaded sleeve; 34. Elastic locking rubber ring; 35. Conical guide sleeve; 36. Annular groove; 37. Fixed threaded sleeve; 4. Suction tube; 5. Negative pressure suction connector; 6. Auxiliary three-way valve; 7. Suction port welding section; 8. Thrombus containing bag; 9. Thrombus crushing mechanism. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] like Figure 1-Figure 7 As shown, a variable-caliber tube-sheath integrated thrombus aspiration catheter with an intra-tube thrombus-breaking function includes a guide tube 2 and an aspiration tube 4. The aspiration tube 4 is slidably inserted into the guide tube 2. The aspiration tube 4 serves as a negative pressure tube for aspirating thrombi, and the outer surfaces of the guide tube 2 and the aspiration tube 4 are both provided with coating sections. The outer surface of the guide tube 2 is wiped with gauze soaked in physiological saline to activate the surface hydrophilic coating for easy use. At the same time, the outer diameter size range of the guide tube 2 is 5-18Fr, and the outer diameter size range of the aspiration tube 4 is 3-16Fr. In this embodiment, the outer diameter of the guide tube 2 is preferably 14Fr, and the outer diameter of the aspiration tube 4 is 12Fr. Here, Fr is the unit of the outer diameter of medical devices such as catheters, and the conversion formula is: 1Fr=1 / 3mm≈0.33mm.

[0033] The catheter also includes a multi-stage adjustable suction port mechanism 1, a locking mechanism 3 and a thrombus crushing mechanism 9; the multi-stage adjustable suction port mechanism 1 is cooperatively arranged at one end of the suction tube 4, and the suction tube 4 is used to drive the multi-stage adjustable suction port mechanism 1 to shrink into the guide tube 2 or to expand step by step from the guide tube 2 to the outside, so as to adjust the caliber of the multi-stage adjustable suction port mechanism 1 according to the actual thrombus suction needs, so as to facilitate the suction of large volume thrombus, and the locking mechanism 3 is cooperatively arranged between the suction tube 4 and the guide tube 2, and the locking mechanism 3 is used to lock the relative position of the suction tube 4 and the guide tube 2, so as to lock the relative position of the suction tube 4 and the guide tube 2 when adjusting the level of the multi-stage adjustable suction port mechanism 1, so as to ensure the stable state of the multi-stage adjustable suction port mechanism 1 and facilitate use.

[0034] The thrombus breaking mechanism 9 includes a plurality of protruding blades. The thrombus breaking mechanism 9 relies on the protruding blades to break up the thrombus, thereby preventing large-volume thrombus from blocking the tube body.

[0035] In some specific embodiments, such as Figure 2 As shown, the multi-stage adjustable suction port mechanism 1 includes an adjustable zoom component 12, a support segment wire 13 and a coating 15. A plurality of adjustable zoom components 12 are provided. The plurality of adjustable zoom components 12 are equidistantly distributed along the axial direction of the suction tube 4, and their sizes increase one by one, so that the entire multi-stage adjustable suction port mechanism 1 is trumpet-shaped, and each adjacent two adjustable zoom components 12 form one stage, which can be divided into multiple stages. Adjacent adjustable zoom components 12 are fixedly connected by the support segment wire 13, and the adjustable zoom component 12 close to the suction tube 4 is also fixedly connected to the end of the suction tube 4 by the support segment wire 13. Multiple support segment wires 13 can be provided according to actual needs. The adjustable zoom component 12 and the support segment wire 13 are both medical shape memory alloys, which are elastic as a whole and can be bent and deformed. Each adjustable zoom component 2 includes a plurality of circumferentially distributed supporting metal structures, and adjacent supporting metal structures are connected together in sequence to form a complete annular body. The coating 15 covers the outside of each adjustable zoom component 12 to facilitate the formation of a thrombus suction guide port.

[0036] After the entire catheter is inserted into the vein, the suction tube 4 slides relative to the guide tube 2, driving the entire multi-stage adjustable suction port mechanism 1 to retract into the inside of the guide tube 2. For details, please refer to Figure 3 As shown, after reaching the location of the thrombus, the suction tube 4 slides relative to the guide tube 2, thereby pushing the multi-stage adjustable suction port mechanism 1 to slide out and unfold, and the multi-stage adjustable suction port mechanism 1 is released step by step with the assistance of the angiography device, so that the adjustment and scaling component 12 at the corresponding position is released from the guide tube 2 to reach a larger caliber, and then suction is performed, so that the thrombus can be completely guided by the adjusted multi-stage adjustable suction port mechanism 1 and drawn into the suction tube 4, thereby reducing the risk of large-volume thrombus being broken and escaped before being sucked into the tube body, causing thrombus blockage at the distal end of the blood vessel.

[0037] In some specific embodiments, the supporting metal structure is a W-shaped structure. When the W-shaped structure shrinks into the guide tube 2, it is easy to be radially folded and stored due to the extrusion effect, and the axial dimension change is reduced. This can avoid the guide tube 2 being too long or incompletely stored.

[0038] It should be noted that the adjustable zoom component 12 may also be composed of structures of other shapes, such as a V-shaped structure.

[0039] In some specific embodiments, in order to prevent the inner wall of the blood vessel from being scratched during the movement of the end of the multi-stage adjustable suction port mechanism 1, a silicone ring 14 is fixedly connected to one end of the multi-stage adjustable suction port mechanism 1 away from the suction tube 4, and the silicone ring 14 can be deformed as the end of the multi-stage adjustable suction port mechanism 1 contracts and expands.

[0040] In some specific embodiments, a suction port welding section 7 is connected between the multi-stage adjustable suction port mechanism 1 and the suction tube 4, and a developing ring is distributed on the suction port welding section 7 to facilitate the developing positioning of the imaging equipment. The suction port welding section 7 facilitates the multi-stage adjustable suction port mechanism 1 and the suction tube 4 to be fixedly connected together, which facilitates stable operation during operation. The suction port welding section 7 is a hollow tubular body, which facilitates the multi-stage adjustable suction port mechanism 1 and the suction tube 4 to be connected to each other.

[0041] In some specific embodiments, such as Figure 6 and Figure 7 As shown, the locking mechanism 3 includes a positioning sleeve 31 and a knob fixing assembly. The positioning sleeve 31 is fixedly sleeved on one end of the guide tube 2, and the two are fixed to each other. The knob fixing assembly is rotatably set on the positioning sleeve 31, and the knob fixing assembly is used to fix the suction tube 4 so that its position remains fixed relative to the positioning sleeve 31 and the guide tube 2.

[0042] Among them, the knob fixing assembly includes a threaded sleeve 33, a fixed threaded sleeve 37, an elastic locking rubber ring 34 and a conical guide sleeve 35. The fixed threaded sleeve 37 is coaxially fixedly connected to one end of the positioning sleeve 31, and the suction tube 4 passes through the fixed threaded sleeve 37. One end of the threaded sleeve 33 is threadedly connected to the fixed threaded sleeve 37. It should be noted here that the inner wall of the threaded sleeve 33 is distributed with threads, and the outer wall of the fixed threaded sleeve 37 is distributed with threads. The threaded sleeve 33 is sleeved on the fixed threaded sleeve 37, and the two are threadedly connected; the elastic locking rubber ring 34 is arranged on the inner side of the other end of the threaded sleeve 33, and the elastic locking rubber ring 34 is used to hold the outer wall of the suction tube 4. It should be noted that the elastic locking rubber ring 34 can be elastically deformed, and its original inner ring size is slightly smaller than the outer diameter of the suction tube 4, so that it is convenient for the elastic locking rubber ring 34 to be squeezed and held tightly on the outside of the suction tube 4 The conical guide sleeve 35 is arranged between the suction pipe 4 and the fixed threaded sleeve 37, and the conical guide sleeve 35 is fixedly connected with the fixed threaded sleeve 37, and the smaller end of the conical guide sleeve 35 exceeds the side of the fixed threaded sleeve 37 close to the elastic locking rubber ring 34. When it is necessary to unlock the fixed state of the relative position of the suction pipe 4 and the guide pipe 2, the threaded sleeve 33 is rotated to rotate and move along the fixed threaded sleeve 37 close to the positioning sleeve 31. During this process, the threaded sleeve 33 drives the elastic locking rubber ring 34 to move the sleeve onto the conical guide sleeve 35, and as the diameter of the conical guide sleeve 35 gradually increases, the elastic locking rubber ring 34 is stretched open, thereby separating from the suction pipe 4, which is convenient for adjusting the position of the suction pipe 4.

[0043] It should be noted that in order to avoid the elastic locking rubber ring 34 from clamping on the outer wall of the suction tube 4 and generating a large resistance during the rotation of the threaded sleeve 33, an annular groove 36 is opened on the inner wall of the threaded sleeve 33, and an annular connector is installed on the outer ring of the elastic locking rubber ring 34, and the annular body is slidably engaged in the annular groove 36. In this way, during the rotation of the threaded sleeve 33, the elastic locking rubber ring 34 does not need to rotate with the threaded sleeve 33.

[0044] In other specific embodiments, the knob fixing assembly can be a fastening bolt, which is threadedly connected to one end of the positioning sleeve 31 and has its end facing the outer wall of the suction tube 4, so as to fix the relative position of the suction tube 4 and the guide tube 2 by tightening.

[0045] In some specific embodiments, in order to prevent blood from seeping out from the gap between the guide tube 2 and the suction tube 4, an annular silicone sheet 32 ​​is fixedly connected to one end of the guide tube 2 away from the multi-stage adjustment suction port mechanism 1, and the inner circle side wall of the annular silicone sheet 32 ​​wraps around the suction tube 4, so as to facilitate the sealing of the gap between the suction tube 4 and the guide tube 2 facing the outside. It should be noted that the annular silicone sheet 32 ​​only wraps and fits the outer wall of the suction tube 4, and is not directly connected together.

[0046] In some specific embodiments, such as Figure 4 As shown, the thrombus breaking mechanism 9 is arranged inside the suction tube 4, and the raised blades of the thrombus breaking mechanism 9 are distributed in a spiral shape along the inner wall of the suction tube 4, so as to facilitate the cutting and breaking of the thrombus entering the suction tube 4 and avoid blockage.

[0047] In other specific embodiments, Figure 5 As shown, the thrombus crushing mechanism 9 is arranged at one end of the multi-stage adjustable suction port mechanism 1 close to the suction tube 4. In this embodiment, the raised blade of the thrombus crushing mechanism 9 can be fixedly connected with a circle of W-shaped structures of the multi-stage adjustable suction port mechanism 1 close to the suction tube 4, so that the raised blade contracts with the W-shaped structure and opens when it expands, so that the large thrombus sucked into the multi-stage adjustable suction port mechanism 1 can be cut into pieces to avoid clogging the tube mouth of the suction tube 4.

[0048] In some specific embodiments, one end of the suction tube 4 away from the multi-stage adjustable suction port mechanism 1 is connected to a negative pressure suction connector 5, and the negative pressure suction connector 5 is used for an external suction pump to facilitate the suction tube 4 to negatively pressure suction thrombus, and can also be connected to a syringe for injecting physiological saline, so as to facilitate emptying the suction tube 4. A thrombus containing bag 8 is also provided on one side of the negative pressure suction connector 5, and the negative pressure suction connector 5 can be set as a three-way tube, which is convenient for connecting the thrombus containing bag 8 and the suction pump at the same time.

[0049] In some specific embodiments, a variable-caliber, sheath-integrated thrombus aspiration catheter with a function of breaking up thrombi in the tube disclosed by the present invention also includes an auxiliary three-way valve 6. The auxiliary three-way valve 6 can be connected to one side of the positioning sleeve 31, and is connected to the space between the aspiration tube 4 and the guide tube 2 through a hose. The auxiliary three-way valve 6 is connected to an external syringe to push physiological saline to complete the emptying of the inside of the guide tube 2 and lubrication of the outer surface of the aspiration tube 4.

[0050] In other specific embodiments, the outer diameter of the guide tube 2 is preferably 6Fr, and the outer diameter of the suction tube 4 is preferably 4Fr.

[0051] In other specific embodiments, the outer diameter of the guide tube 2 is 7Fr, and the outer diameter of the suction tube 4 is 5Fr.

[0052] In order to facilitate the understanding of the embodiments of this solution by those skilled in the art, the working principle of this solution is briefly described in combination with specific application scenarios:

[0053] First, use gauze soaked in saline to wipe the outer surface of the guide tube 2 to activate the hydrophilic coating on the surface, and connect a syringe for injecting saline through the negative pressure suction connector 5 to facilitate emptying the suction tube 4. Use the auxiliary three-way valve 6 to connect an external syringe to inject saline to complete the emptying of the inside of the guide tube 2 and lubricate the outer surface of the suction tube 4.

[0054] Then check whether the locking mechanism 3 is in the locked state and whether the multi-stage adjustable suction port mechanism 1 is completely retracted into the guide tube 2. After confirming that it is in the locked state and the multi-stage adjustable suction port mechanism 1 is in the retracted state, introduce the instrument into the vein, and reach the location of the thrombus with the assistance of the imaging device. Then unlock the locking mechanism 3, so that the relative positions of the suction tube 4 and the guide tube 2 are unlocked, and then the suction tube 4 slides relative to the guide tube 2, thereby pushing the multi-stage adjustable suction port mechanism 1 to slide out of the guide tube 2 and unfold, and the multi-stage adjustable suction port mechanism is released step by step with the assistance of the imaging device. 1, that is, the adjustment and scaling component 12 at the corresponding position is released from the guide tube 2, and is supported and unfolded by the connected support section metal wire 13 to reach a larger caliber. After reaching the appropriate caliber, the relative positions of the suction tube 4 and the guide tube 2 are locked by the locking mechanism 3, and then the suction tube 4 is connected to the suction pump by the negative pressure suction connector 5 for suction, so that the thrombus is completely guided by the adjusted multi-stage adjustment suction port mechanism 1 and sucked into the suction tube 4, reducing the risk of large-volume thrombus being broken and escaped before being sucked into the tube body, causing thrombus blockage at the distal end of the blood vessel.

[0055] After entering the multi-stage adjustable suction port mechanism 1 , a large thrombus can be broken up by a thrombus breaking mechanism 9 distributed at one end of the multi-stage adjustable suction port mechanism 1 close to the suction tube 4 or distributed inside the suction tube 4 .

[0056] Several embodiments of the present invention are described in detail above, but the embodiments of the present invention are not limited thereto and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A variable-caliber tube-sheath integrated thrombus aspiration catheter with a function of breaking thrombi in the tube, comprising a guide tube (2) and an aspiration tube (4), wherein the aspiration tube (4) is slidably inserted into the guide tube (2), characterized in that: Also includes: A multi-stage adjustable suction port mechanism (1); the multi-stage adjustable suction port mechanism (1) is arranged in cooperation with one end of a suction pipe (4), and the suction pipe (4) is used to drive the multi-stage adjustable suction port mechanism (1) to retract into the guide pipe (2) or to expand outward from the guide pipe (2) step by step; A locking mechanism (3) is arranged between the suction tube (4) and the guide tube (2), and the locking mechanism (3) is used to lock the relative position of the suction tube (4) and the guide tube (2).

2. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 1, characterized in that: The multi-stage adjustable suction port mechanism (1) comprises an adjustable zoom component (12), a supporting metal wire (13) and a coating (15), wherein a plurality of the adjustable zoom components (12) are provided, and each of the adjustable zoom components (12) comprises a plurality of circumferentially distributed supporting metal structures, and the plurality of adjustable zoom components (12) are equidistantly distributed along the axial direction of the suction pipe (4), and the sizes of the plurality of adjustable zoom components (12) are gradually increased, and adjacent adjustable zoom components (12) are fixedly connected by the supporting metal wire (13).

3. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 2, characterized in that: The supporting metal structure is a W-shaped structure.

4. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 1, characterized in that: One end of the multi-stage adjustable suction port mechanism (1) away from the suction pipe (4) is fixedly connected to a silicone ring (14).

5. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 1, characterized in that: The locking mechanism (3) comprises a positioning sleeve (31) and a knob fixing assembly, wherein the positioning sleeve (31) is fixedly sleeved on one end of the guide tube (2), and the knob fixing assembly is rotatably arranged on the positioning sleeve (31), and the knob fixing assembly is used to fix the suction tube (4).

6. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 5, characterized in that: The knob fixing assembly comprises a threaded sleeve (33), a fixed threaded sleeve (37), an elastic locking rubber ring (34) and a cone guide sleeve (35); the fixed threaded sleeve (37) is coaxially fixedly connected to one end of the positioning sleeve (31), and the suction pipe (4) passes through the fixed threaded sleeve (37); one end of the threaded sleeve (33) is threadedly connected to the fixed threaded sleeve (37); the elastic locking rubber ring (34) is arranged on the inner side of the other end of the threaded sleeve (33), and the elastic locking rubber ring (34) is used to hold the outer wall of the suction pipe (4); the cone guide sleeve (35) is arranged between the suction pipe (4) and the fixed threaded sleeve (37), and the cone guide sleeve (35) is fixedly connected to the fixed threaded sleeve (37).

7. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 1, characterized in that: An end of the guide tube (2) away from the multi-stage adjustable suction port mechanism (1) is fixedly connected to an annular silicone sheet (32), and the annular silicone sheet (32) wraps the suction tube (4).

8. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 1, characterized in that: It also comprises a thrombus-breaking mechanism (9), wherein the thrombus-breaking mechanism (9) comprises a plurality of protruding blades, and the thrombus-breaking mechanism (9) relies on the protruding blades to break the thrombus.

9. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 8, characterized in that: The thrombus breaking mechanism (9) is arranged on the inner side of the suction tube (4), and the raised blades of the thrombus breaking mechanism (9) are distributed in a spiral shape along the inner wall of the suction tube (4).

10. The variable-caliber tube-sheath integrated thrombus aspiration catheter with the function of breaking thrombi in the tube according to claim 8, characterized in that: The thrombus breaking mechanism (9) is arranged at one end of the multi-stage adjustment suction port mechanism (1) close to the suction tube (4).

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