Sunscreen cream composition with multiple photoprotective uv filters

Abstract

The present disclosure provides a sunscreen cream composition having a variety of photoprotective UV filters. There is provided a UV filter composition comprising: three UV-B filters; a UV-A light filter; and a UV-A + UV-B broadband filter agent.

Description

[0001] This application is a divisional application of an application with a filing date of November 19, 2020, an international application number of PCT / US2020 / 061238, a national application number of 202080080833.7, and an invention name of "Sunscreen composition with multiple photoprotective UV filters".

[0002] Related Applications

[0003] This application claims the benefit of priority to U.S. Provisional Patent Application Serial No. 62 / 937,989, filed on November 20, 2019, entitled “SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS”, the disclosure of which is incorporated herein by reference in its entirety. This application also claims the benefit of priority to U.S. Provisional Patent Application Serial No. 62 / 948,990, filed on December 17, 2019, entitled “SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS”, the disclosure of which is incorporated herein by reference in its entirety.

[0004] Disclosed herein are novel compositions for use as sunscreens comprising a plurality of photoprotective UV filters. The combination of UV filters provides effective protection from a wide range of UV wavelengths when applied to exposed skin. Technical Field

[0005] The present invention relates to sunscreen compositions. Background Art

[0006] Exposure to sunlight poses health risks that have increased in significance in recent decades. Acute exposure to sunlight can result in sunburn, which is characterized by skin irritation and redness. More importantly, prolonged exposure to the sun increases the risk of skin cancer. Of the various subtypes of skin cancer, melanoma poses the greatest risk because it is aggressive and difficult to treat if not caught before it spreads. The American Cancer Society estimates that nearly 100,000 cases of melanoma will be diagnosed in 2019, with approximately 7,000 deaths. Finally, exposure to the sun can cause premature skin aging, hair damage, and eye damage, including cataracts.

[0007] The ultraviolet region of solar radiation falling between 200 nm and 400 nm can be classified into three regions: 320 nm to 400 nm (UV-A), 290 nm to 320 nm (UV-B), and 200 nm to 290 nm (UV-C), the latter of which does not generally penetrate the Earth's atmosphere. Historically, more attention has been paid to the health risks of UV-B exposure; however, more recently, more is known about the potential damage that can be caused by UV-A, as well as melanoma and other skin cancers. Therefore, protection from excessive UV-A and UV-B radiation is an important part of personal care.

[0008] Although sunscreens have a long history of commercial use, recently discovered health and (especially) environmental issues are promoting the development of new compounds and compositions for improving preventive properties and increasing consumer acceptance. The need for methods for new sunscreens is significantly unmet. The present disclosure meets these and other needs, as demonstrated by reference to the following disclosure.

[0009] The invention provides a sunscreen composition.

[0010] Provided is a UV filter composition comprising: three UV-B filters; a UV-A filter; and a UV-A+UV-B broadband filter. Summary of the invention

[0011] Also provided is a sunscreen composition comprising the UV filter composition described herein.

[0012] Also provided is a method for protecting skin from sun damage, the method comprising applying to the skin the sunscreen composition described herein.

[0013] These and other aspects of the invention will become apparent with reference to the following detailed description.To this end, various references are set forth herein that describe in more detail certain background information, procedures, compounds and / or compositions, and each is hereby incorporated by reference in its entirety. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The drawings illustrate generally, by way of example and not limitation, various embodiments discussed in this document.

[0015] Figure 1 is a graph showing that the in vivo SPF of Formula 1 and Formula 2 is substantially the same as the SPF of the Comparative Formula according to Example 5.

[0016] Figure 2 is a graph showing that the PPD of Formula 1 according to Example 5 is substantially the same as that of the Comparative Formula.

[0017] Figure 3is a graph showing that the SPF / PPD quotient of Formula 1 according to Example 5 is substantially the same as that of the Comparative Formula.

[0018] Figure 4 is a graph showing the improvement in SPF of Formula 3 relative to the Comparative Formula according to Example 5.

[0019] Figure 5 is a graph showing that the SPF / PPD quotient of Formula 3 according to Example 5 is substantially the same as that of the Comparative Formula.

[0020] Figure 6 is a graph showing that the SPF / PPD quotient of Formula 3 according to Example 5 is substantially the same as that of the Comparative Formula. DETAILED DESCRIPTION

[0021] In the following description, certain specific details are set forth in order to provide a thorough understanding of the various embodiments. However, one of ordinary skill in the art will appreciate that the present invention can be practiced without these details. In other instances, well-known structures are not shown or described in detail to avoid unnecessary confusion in the description of the embodiments. Unless the context otherwise requires, throughout the specification and the appended claims, the word "comprise" and its variations, such as "comprises" and "comprising", will be interpreted in an open and inclusive sense, i.e., interpreted as "including but not limited to". In addition, the titles provided herein are for convenience only and do not describe the scope or meaning of the claimed invention.

[0022] Throughout this specification, references to "one embodiment" or "an embodiment" or "some embodiments" or "a certain embodiment" mean that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the phrases "in one embodiment" or "in an embodiment" or "in some embodiments" or "in a certain embodiment" appearing in different places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.

[0023] Also, as used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the content clearly dictates otherwise.

[0024] Where applicable, chemicals are designated by their INCI names. Additional information, including definitions, suppliers, and trade names, can be found in the International Cosmetic Ingredient Dictionary and Handbook, 16th Edition, published by the Personal Care Products Council, Washington DC, under the appropriate INCI monograph. It is also available through the Personal Care Products Council On-Line INFOBASE (http: / / online.personalcarecouncil.org / jsp / Home.jsp).

[0025] When exposing a range of values ​​and using "from n 1 to n 2 " or "between n 1 With n 2 ", where n 1 and n 2 If a number is a number, the symbol is intended to include the number itself and the range between the numbers unless otherwise specified. The range can be an integer or can be between and including the end values. For example, the range of "2 to 6 carbons" is intended to include two, three, four, five, and six carbons, because carbon exists in integer units. For example, 1 µM to 3 µM (micromolar), which is intended to include 1 µM, 3 µM, and every number in between, is compared to any number in the significant figure (e.g., 1.255 µM, 2.1 µM, 2.9999 µM, etc.).

[0026] As used herein, the term "about" is intended to quantify the numerical value it modifies, thereby indicating that such value may vary within a margin of error. When a specific margin of error is not recited, such as the standard deviation from the mean value given in a data graph or table, the term "about" should be understood to mean that the range of the recited values ​​and the range to the stated number will be taken into account by rounding off the number.

[0027] Unless otherwise indicated, percentages or concentrations refer to percentages or concentrations by weight (ie, % (W / W)). Unless otherwise indicated, all ranges are inclusive, for example, "from 4 to 9" includes the values ​​4 and 9.

[0028] As used herein, the term "cosmetically effective amount" refers to an amount of a physiologically active compound or composition sufficient to treat one or more conditions but low enough to avoid serious side effects. The cosmetically effective amount of a compound or composition will vary with the condition being treated, the age and physical condition of the end user, the severity of the condition being treated / prevented, the duration of treatment, the nature of other treatments, the specific compound or product / composition employed, the cosmetically acceptable carrier used, and similar factors.

[0029] As used herein, the term "cosmetically acceptable" refers to compositions whose ingredients are suitable for use in contact with tissue (eg, skin) without undue toxicity, irritation, incompatibility, instability, allergic response, or other untoward effect.

[0030] The term "sun protection factor", abbreviated "SPF", or "UV protection factor" is determined using a combination of experimental and theoretical absorption data as disclosed in US 6,820,014, which is incorporated herein by reference. Other methods for determining SPF are known in the art.

[0031] The term "persistent pigment darkening", abbreviated "PPD", is a method of measuring UVA protection, similar to the SPF method of measuring sunburn protection. Instead of measuring erythema, the PPD method uses UVA radiation to cause persistent darkening or tanning of the skin. In theory, a sunscreen with a PPD rating of 10 should allow 10 times more UVA exposure than no protection. Methods for determining PPD are known in the art.

[0032] As used herein, the term "UV-A" refers to electromagnetic radiation having a wavelength between 320 nm and 400 nm.

[0033] As used herein, the term "UV-B" refers to electromagnetic radiation having a wavelength between 290 nm and 320 nm.

[0034] As used herein, the term "broad spectrum" UV refers to electromagnetic radiation having a wavelength of 290 nm to 400 nm. The determination of "broad spectrum" is made in accordance with 21 CFR 201.327(j) (2019).

[0035] As used herein, the term "critical wavelength" is the wavelength at which the integral of the spectral absorbance curve is 90% of the integral within the UV spectrum from 290 nm to 400 nm.

[0036] As used herein, the term "photostable" refers to the ability of a molecule to remain intact under irradiation. Photostability can be quantified by comparing the degree of protection and subsequent irradiation. See, for example, Pissavini et al. (2012) "New Method to Reproduce In Vitro Cosmetic Product Photostability Findings", Cosmetics & Toiletries 127(3):208-218, which is incorporated by reference for all purposes. Other methods known in the art may also be used to determine photostability.

[0037] As used herein, the term "topical application" refers to direct application by spraying, wiping or spreading on the cuticle or scalp. Topical application can be performed by hand or using an applicator such as a wipe, a roller or a sprayer.

[0038] As used herein, the term "cosmetic agent" refers to an aesthetic substance or preparation that maintains, restores, imparts, simulates, or enhances the beautiful appearance of the body or appears to enhance beauty or youthfulness, particularly as it relates to the appearance of tissue or skin.

[0039] As used herein, the term "sunscreen composition" refers to a formulation that absorbs and / or reflects some of the solar ultraviolet (UV) radiation, including but not limited to: a spray, oil, lotion, cream, gel, butter, paste, ointment, stick, powder, wipes, towelette, body wash, shampoo or other topical product. Thus, the sunscreen composition will provide protection against the negative effects of sun exposure, e.g., sunburn, premature aging, etc.

[0040] A UV filter composition is provided, which comprises: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter. A UV filter composition is also provided, which consists of: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter.

[0041] In certain embodiments, the UV-A filter is selected from:

[0042] ●Butyl methoxydibenzoylmethane or 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione;

[0043] ● p-Terephthalylidene dicamphorsulfonic acid or 3,3'-(1,4-phenylenedimethylene)bis(7,7-dimethyl-2-oxobicyclo-[2.2.1]hept-1-ylmethanesulfonic acid) and salts thereof;

[0044] ●Menthyl anthranilate;

[0045] ●Bisdisulizole Disodium or disodium phenyldibenzimidazole tetrasulfonate;

[0046] ●Diethylaminohydroxybenzoyl hexyl benzoate; and

[0047] ●Dimethoxyphenyl-[1-(3,4)]-4,4-dimethyl-1,3-pentanedione.

[0048] In certain embodiments, the UV-A filter is selected from butyl methoxydibenzoylmethane, diethylaminohydroxybenzoyl hexyl benzoate, disodium phenyl dibenzoimidazole tetrasulfonate, and terephthalylidene dicamphor sulfonic acid.

[0049] In certain embodiments, the UV-A filter is selected from the group consisting of butyl methoxydibenzoylmethane and menthyl anthranilate.

[0050] In certain embodiments, the UV-A filter is butyl methoxydibenzoylmethane.

[0051] In certain embodiments, the three UV-B filters are independently selected from:

[0052] ●3-benzylidene camphor;

[0053] ●Benzal camphorsulfonic acid;

[0054] ●enzacamene or 4-methylbenzylidene camphor or 4-MBC;

[0055] ●2-ethoxyethyl-p-methoxyoctanoate;

[0056] DEA methoxycinnamate;

[0057] ●Iscotrizinol or diethylhexyl butyramido triazone or benzoic acid, 4,4-{[6-[[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3-5-triazine-2,4-diyl]diimino}bis-,bis(2-ethylhexyl) ester;

[0058] ●Dioleyl trioleate;

[0059] ●Diisopropyl methyl cinnamon;

[0060] ●Ethyl dihydroxypropyl PABA;

[0061] ●Ethylhexyl dimethoxybenzylidene dioxoimidazole propionate;

[0062] ●Octyl dimethyl-PABA or 2-ethylhexyl 4-(dimethylamino)benzoate;

[0063] ●Octyl methoxycinnamate or 2-ethylhexyl 4-methoxycinnamate;

[0064] ●Octyl salicylate or 2-ethylhexyl salicylate;

[0065] ● Octyl triazone or ethylhexyl triazone or 2,4,6-triphenylamino-(p-carbon-2'-ethylhexyl-1'-oxy)-1,3,5-triazine;

[0066] Ferulic acid;

[0067] ●Ethylhexanoate dimethoxycinnamate glyceryl;

[0068] ●Glyceryl PABA;

[0069] ●Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester;

[0070] ●Isoamyl p-methoxycinnamate or isopentyl-4-methoxycinnamate;

[0071] ●Isoamyl trimethoxycinnamate trisiloxane;

[0072] ●Isopropyl benzyl salicylate;

[0073] ●Isopropyl methoxycinnamate;

[0074] ●Lawsone + dihydroxyacetone;

[0075] ●4-Methylbenzylidene camphor;

[0076] ●2-Ethylhexyl 2-cyano-3,3-diphenylacrylate;

[0077] ●PABA;

[0078] PEG-25 PABA;

[0079] ●Amyl dimethyl PABA;

[0080] ● Phenylbenzimidazole sulfonic acid or 2-phenylbenzimidazole-5-sulfonic acid and their potassium, sodium and triethanolamine salts;

[0081] ● Polyacrylamide methylbenzylidene camphor;

[0082] ●Polysilicone-15 or dimethicone diethylbenzylidenemalonate;

[0083] Salicylic acid; and

[0084] ●TEA salicylic acid (triethanolamine salicylate).

[0085] In certain embodiments, the three UV-B filters are independently selected from ethylhexyldimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate, octocrylene, PABA, and phenylbenzimidazole sulfonic acid. In certain embodiments, any composition described herein may be free of octocrylene.

[0086] In certain embodiments, the three UV-B filters are independently selected from 3-benzylidene camphor, benzylidene camphor sulfonic acid, camphor benzalkonium methyl sulfate, diethylhexyl butamido triazone, ethylhexyl dimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, ethylhexyl triazone, homosalate, isoamyl p-methoxycinnamate, 4-methylbenzylidene camphor, octocrylene, PABA, PEG-25 PABA, phenylbenzimidazole sulfonic acid, polyacrylamidomethylbenzylidene camphor and polysilicone-15. In certain embodiments, the three UV-B filters are independently selected from cinoxate, ethylhexyl dimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate, octocrylene, PABA, phenylbenzimidazole sulfonic acid and TEA salicylate. In certain embodiments, the three UV-B filters are independently selected from isoamyl p-methoxycinnamate, ethylhexyl triazone, diethylhexyl butamido triazone, and ethylhexyl salicylate. In certain embodiments, the three UV-B filters are independently selected from isoamyl p-methoxycinnamate, ethylhexyl triazone, and octyl salicylate.

[0087] In certain embodiments, broadband UV-A and UV-B filters are selected from:

[0088] ●Benzophenone;

[0089] ●Benzophenone-1;

[0090] ●Benzophenone-2;

[0091] ●Benzophenone-3 or 2-hydroxy-4-methoxybenzophenone;

[0092] ●Benzophenone-4 or 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid (benzophenone-5) and its sodium salt;

[0093] ●Benzophenone-5;

[0094] ●Benzophenone-6;

[0095] ●Dioxybenzone (benzophenone-8);

[0096] ●Benzophenone-9;

[0097] ●β-2-glucopyranosyloxypropyl hydroxybenzophenone;

[0098] Bemotrizinol or bis-ethylhexyloxyphenol methoxyphenyl triazine or 2,2'-(6-(4-methoxyphenyl)-1,3,5-triazine-2,4-diyl)bis(5-((2-ethylhexyl)oxy)phenol);

[0099] Drometrizole

[0100] ●Dromtriazole trisiloxane or phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-(trimethylsilyl)oxy)-disiloxane)propyl;

[0101] ●Bisoctrizol or methylene bis-benzotriazolyl tetramethylbutylphenol;

[0102] Titanium dioxide; and

[0103] ●Zinc oxide.

[0104] In certain embodiments, the broadband UV-A and UV-B filters are selected from benzophenone-3 and titanium dioxide. In certain embodiments, the broadband UV-A and UV-B filters are selected from benzophenone-3, benzophenone-4, benzophenone-5, bis-ethylhexyloxyphenol methoxyphenyl triazine, tolyltriazole trisiloxane, methylene bis-benzotriazolyl tetramethylbutylphenol and titanium dioxide. In certain embodiments, the broadband UV-A and UV-B filters are selected from benzophenone-3, benzophenone-4, benzophenone-8, titanium dioxide and zinc oxide. In certain embodiments, the UV-A + UV-B broadband filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0105] Also provided is a UV filter composition, which comprises isoamyl p-methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0106] Also provided is a UV filter composition consisting of isoamyl p-methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0107] Also provided is a UV filter composition comprising diethylhexyl butyramido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0108] Also provided is a UV filter composition consisting of diethylhexyl butyramido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0109] Also provided is a UV filter composition, which comprises diethylhexyl butyramido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0110] Also provided is a UV filter composition consisting of diethylhexyl butyramido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0111] Also provided is a sunscreen composition comprising a UV filter composition, wherein the UV filter composition comprises isoamyl p-methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0112] Also provided is a sunscreen composition comprising a UV filter composition, wherein the UV filter composition comprises diethylhexyl butyramido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0113] Also provided is a sunscreen composition comprising a UV filter composition, wherein the UV filter composition comprises diethylhexyl butyramido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0114] In certain embodiments, the sunscreen composition does not include nanoparticles.

[0115] In certain embodiments, the sunscreen compositions do not include benzophenone-3.

[0116] In certain embodiments, the sunscreen composition excludes octyl methoxycinnamate.

[0117] In certain embodiments, the composition excludes cinnamate esters other than isoamyl p-methoxycinnamate.

[0118] In certain embodiments, the sunscreen composition does not include 2-ethylhexyl 2-cyano-3,3-diphenylacrylate.

[0119] In certain embodiments, the sunscreen composition does not include 2-(benzotriazol-2-yl)-4,6-di-tert-butylphenol, 2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol, 2-(benzotriazol-2-yl)-4,6-bis-(1,1-dimethylpropyl)-phenol, or 2-(benzotriazol-2-yl)-6-butane-2-yl-4-tert-butylphenol.

[0120] In certain embodiments, each of the UV filters in the sunscreen composition is present in an amount of about 0.1 w / w% to about 25 w / w%, about 0.1 w / w% to about 20 w / w%, about 0.1 w / w% to about 18 w / w%, about 0.1 w / w% to about 15 w / w%, about 0.1 w / w% to about 12 w / w%, about 0.1 w / w% to about 10 w / w%, 0.1 w / w% to about 8 w / w%, about 0.1 to about 6 w / w%, wherein the weight percentages are based on the total weight of the sunscreen composition.

[0121] In certain embodiments, the sunscreen composition comprises less than about 35 w / w% UV filters. In certain embodiments, the sunscreen composition comprises between about 5 w / w% and about 25 w / w% UV filters. In certain embodiments, the sunscreen composition comprises about 20 w / w% UV filters.

[0122] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0123] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octylsalicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0124] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0125] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

[0126] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:5.5:1.

[0127] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

[0128] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

[0129] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2.

[0130] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1.

[0131] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0132] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0133] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0134] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:6.

[0135] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

[0136] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:6.

[0137] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

[0138] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

[0139] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

[0140] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

[0141] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 3:8.5:2.

[0142] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

[0143] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

[0144] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

[0145] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

[0146] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

[0147] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[0148] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

[0149] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0150] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0151] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0152] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

[0153] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[0154] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

[0155] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0156] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0157] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0158] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[0159] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[0160] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[0161] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[0162] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[0163] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[0164] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[0165] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[0166] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[0167] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[0168] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[0169] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[0170] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

[0171] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[0172] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

[0173] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter isopentyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[0174] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[0175] In certain embodiments, the sunscreen composition includes the following: UV-A filter butyl methoxydibenzoylmethane, UV-B filter isopentyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butyramido triazone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[0176] In certain embodiments, the ratio of UVA / UVB filters in the sunscreen composition is between about 0.6 and about 0.8. In certain embodiments, the ratio of UVA / UVB filters in the sunscreen composition is about 0.7.

[0177] In certain embodiments, the sunscreen composition has an average critical wavelength of about 370 nm or greater. In certain embodiments, the sunscreen composition has an average critical wavelength of about 375 nm.

[0178] In certain embodiments, the sunscreen composition has an SPF of at least about 15, such as about 15. In certain embodiments, the composition has an SPF of at least about 30. In certain embodiments, the composition has an SPF of at least about 50. In certain embodiments, the composition has an SPF of at least about 60.

[0179] In certain embodiments, the sunscreen composition further includes a solubilizing agent. In certain embodiments, the solubilizing agent plays a role in dissolving the UV filter. In certain embodiments, the solubilizing agent plays a role in preventing solid particles from forming. In certain embodiments, the sunscreen composition includes a lower level of solubilizing agent. In certain embodiments, the ratio of UV solubilizing agent to UV filter is between about 0.5 and about 2.3, such as 0.5, about 0.6, about 0.7, about 0.8, about 0.9, about 1, about 1.1, about 1.2, about 1.3, about 1.4, about 1.5, about 1.6, about 1.7, about 1.8, about 1.9 or about 2.0.

[0180] In certain embodiments, the sunscreen composition includes up to about 36 w / w% of a solubilizer. In certain embodiments, the sunscreen composition includes about 20 w / w% of a solubilizer. In certain embodiments, the sunscreen composition includes less than about 20 w / w% of a solubilizer. In certain embodiments, the sunscreen composition includes between about 15 w / w% and 20 w / w% of a solubilizer.

[0181] In certain embodiments, the sunscreen composition comprises a solubilizing agent between about 0.1 w / w% and about 5 w / w%. In certain embodiments, the sunscreen composition comprises a solubilizing agent between about 0.1 w / w% and about 15 w / w%. In certain embodiments, the sunscreen composition comprises a solubilizing agent between about 0.1 w / w% and about 25 w / w%. In certain embodiments, the sunscreen composition comprises a solubilizing agent between about 0.1 w / w% and about 35 w / w%.

[0182] In certain embodiments, the sunscreen composition includes at least one solubilizer selected from the group consisting of: diisopropyl sebacate, dicaprylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyl octyl salicylate, C12-15 alkyl benzoate, and diethylhexyl succinate. In certain embodiments, the sunscreen composition includes at least one solubilizer selected from the group consisting of: diisopropyl sebacate, diisopropyl adipate, dicaprylyl carbonate, dibutyl adipate, butyl octyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate, and isopropyl lauroyl sarcosinate.

[0183] In certain embodiments, the sunscreen composition includes two solubilizers selected from the group consisting of diisopropyl sebacate, diisopropyl adipate, dicaprylyl carbonate, dibutyl adipate, butyloctyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate, and isopropyl lauroyl sarcosinate. In certain embodiments, the sunscreen composition includes three solubilizers selected from the group consisting of diisopropyl sebacate, diisopropyl adipate, dicaprylyl carbonate, dibutyl adipate, butyloctyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate, and isopropyl lauroyl sarcosinate.

[0184] In certain embodiments, the sunscreen composition comprises 0.1 w / w % to 5 w / w % of ethylhexyl salicylate and optionally at least one additional solubilizer.

[0185] In certain embodiments, the sunscreen composition comprises 0.1 w / w% to 25 w / w% of at least one solubilizer selected from the group consisting of dibutyl adipate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate, and isopropyl lauroyl sarcosinate, and optionally at least one additional solubilizer.

[0186] In certain embodiments, the sunscreen composition comprises 0.1 w / w% to 25 w / w% of at least one solubilizer selected from diisopropyl sebacate, diisopropyl adipate, dicaprylyl carbonate, and decyl cocoate, and optionally at least one additional solubilizer.

[0187] In certain embodiments, the sunscreen composition comprises:

[0188] The UV-A filter is butyl methoxydibenzoylmethane;

[0189] The first UV-B filter is ethylhexyl triazone;

[0190] The second UV-B filter is octyl salicylate;

[0191] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0192] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0193] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1, and

[0194] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0195] In certain embodiments, the sunscreen composition comprises:

[0196] The UV-A filter is butyl methoxydibenzoylmethane;

[0197] The first UV-B filter is ethylhexyl triazone;

[0198] The second UV-B filter is octyl salicylate;

[0199] The third UV-B filter is diethylhexyl butyramido triazone; and

[0200] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0201] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2: 5.5: 1.

[0202] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 8% to 10% diisopropyl sebacate.

[0203] In certain embodiments, the sunscreen composition comprises:

[0204] The UV-A filter is butyl methoxydibenzoylmethane;

[0205] The first UV-B filter is isoamyl p-methoxycinnamate;

[0206] The second UV-B filter is octyl salicylate;

[0207] The third UV-B filter is diethylhexyl butyramido triazone; and

[0208] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0209] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1, and

[0210] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0211] In certain embodiments, the sunscreen composition comprises:

[0212] The UV-A filter is butyl methoxydibenzoylmethane;

[0213] The first UV-B filter is ethylhexyl triazone;

[0214] The second UV-B filter is octyl salicylate;

[0215] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0216] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0217] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:2, and

[0218] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0219] In certain embodiments, the sunscreen composition comprises:

[0220] The UV-A filter is butyl methoxydibenzoylmethane;

[0221] The first UV-B filter is ethylhexyl triazone;

[0222] The second UV-B filter is octyl salicylate;

[0223] The third UV-B filter is diethylhexyl butyramido triazone; and

[0224] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0225] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2, and

[0226] Wherein the composition includes a solubilizing agent dibutyl adipate, such as from about 8% to about 11% dibutyl adipate, for example from about 9% to about 10%.

[0227] In certain embodiments, the sunscreen composition comprises:

[0228] The UV-A filter is butyl methoxydibenzoylmethane;

[0229] The first UV-B filter is isoamyl p-methoxycinnamate;

[0230] The second UV-B filter is octyl salicylate;

[0231] The third UV-B filter is diethylhexyl butyramido triazone; and

[0232] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0233] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1, and

[0234] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0235] In certain embodiments, the sunscreen composition comprises:

[0236] The UV-A filter is butyl methoxydibenzoylmethane;

[0237] The first UV-B filter is ethylhexyl triazone;

[0238] The second UV-B filter is octyl salicylate;

[0239] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0240] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0241] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2, and

[0242] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0243] In certain embodiments, the sunscreen composition comprises:

[0244] The UV-A filter is butyl methoxydibenzoylmethane;

[0245] The first UV-B filter is isoamyl p-methoxycinnamate;

[0246] The second UV-B filter is octyl salicylate;

[0247] The third UV-B filter is diethylhexyl butyramido triazone; and

[0248] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0249] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2, and

[0250] The composition includes a solubilizing agent, diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, for example about 6% to about 8% diisopropyl sebacate.

[0251] In certain embodiments, a sunscreen composition comprises, wherein:

[0252] The UV-A filter is butyl methoxydibenzoylmethane;

[0253] The first UV-B filter is ethylhexyl triazone;

[0254] The second UV-B filter is octyl salicylate;

[0255] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0256] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0257] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0258] Wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, for example about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0259] In certain embodiments, the sunscreen composition comprises:

[0260] The UV-A filter is butyl methoxydibenzoylmethane;

[0261] The first UV-B filter is ethylhexyl triazone;

[0262] The second UV-B filter is octyl salicylate;

[0263] The third UV-B filter is diethylhexyl butyramido triazone; and

[0264] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0265] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0266] Wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, for example about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0267] In certain embodiments, the sunscreen composition comprises:

[0268] The UV-A filter is butyl methoxydibenzoylmethane;

[0269] The first UV-B filter is isoamyl p-methoxycinnamate;

[0270] The second UV-B filter is octyl salicylate;

[0271] The third UV-B filter is diethylhexyl butyramido triazone; and

[0272] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0273] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0274] Wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, for example about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0275] In certain embodiments, the sunscreen composition comprises:

[0276] The UV-A filter is butyl methoxydibenzoylmethane;

[0277] The first UV-B filter is ethylhexyl triazone;

[0278] The second UV-B filter is octyl salicylate;

[0279] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0280] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0281] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:17:6, and

[0282] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 18% to about 20% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 18.5% to about 19.5% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0283] In certain embodiments, the sunscreen composition comprises:

[0284] The UV-A filter is butyl methoxydibenzoylmethane;

[0285] The first UV-B filter is ethylhexyl triazone;

[0286] The second UV-B filter is octyl salicylate;

[0287] The third UV-B filter is diethylhexyl butyramido triazone; and

[0288] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0289] wherein the mass ratio of the UV-A filter to the UV-B filter to the broadband filter is about 6:17:4, and

[0290] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 18% to about 20% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 18.5% to about 19.5% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0291] In certain embodiments, the sunscreen composition comprises:

[0292] The UV-A filter is butyl methoxydibenzoylmethane;

[0293] The first UV-B filter is isoamyl p-methoxycinnamate;

[0294] The second UV-B filter is octyl salicylate;

[0295] The third UV-B filter is diethylhexyl butyramido triazone; and

[0296] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0297] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6, and

[0298] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 16% to about 18% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 16.5% to about 17.5% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0299] In certain embodiments, the sunscreen composition comprises:

[0300] The UV-A filter is butyl methoxydibenzoylmethane;

[0301] The first UV-B filter is ethylhexyl triazone;

[0302] The second UV-B filter is octyl salicylate;

[0303] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0304] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0305] wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1, and

[0306] Wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.

[0307] In certain embodiments, a sunscreen composition comprises, wherein:

[0308] The UV-A filter is butyl methoxydibenzoylmethane;

[0309] The first UV-B filter is ethylhexyl triazone;

[0310] The second UV-B filter is octyl salicylate;

[0311] The third UV-B filter is diethylhexyl butyramido triazone; and

[0312] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0313] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 3:8.5:2, and

[0314] Wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.

[0315] In certain embodiments, the sunscreen composition comprises:

[0316] The UV-A filter is butyl methoxydibenzoylmethane;

[0317] The first UV-B filter is isoamyl p-methoxycinnamate;

[0318] The second UV-B filter is octyl salicylate;

[0319] The third UV-B filter is diethylhexyl butyramido triazone; and

[0320] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0321] wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1, and

[0322] Wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.

[0323] In certain embodiments, a sunscreen composition comprises, wherein:

[0324] The UV-A filter is butyl methoxydibenzoylmethane;

[0325] The first UV-B filter is ethylhexyl triazone;

[0326] The second UV-B filter is octyl salicylate;

[0327] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0328] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0329] w wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

[0330] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0331] In certain embodiments, a sunscreen composition comprises, wherein:

[0332] The UV-A filter is butyl methoxydibenzoylmethane;

[0333] The first UV-B filter is ethylhexyl triazone;

[0334] The second UV-B filter is octyl salicylate;

[0335] The third UV-B filter is diethylhexyl butyramido triazone; and

[0336] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0337] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0338] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0339] In certain embodiments, the sunscreen composition comprises:

[0340] The UV-A filter is butyl methoxydibenzoylmethane;

[0341] The first UV-B filter is isoamyl p-methoxycinnamate;

[0342] The second UV-B filter is octyl salicylate;

[0343] The third UV-B filter is diethylhexyl butyramido triazone; and

[0344] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0345] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

[0346] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0347] In certain embodiments, the sunscreen composition comprises:

[0348] The UV-A filter is butyl methoxydibenzoylmethane;

[0349] The first UV-B filter is ethylhexyl triazone;

[0350] The second UV-B filter is octyl salicylate;

[0351] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0352] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0353] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0354] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 16% to about 18% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 16.5% to about 17.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0355] In certain embodiments, the sunscreen composition comprises:

[0356] The UV-A filter is butyl methoxydibenzoylmethane;

[0357] The first UV-B filter is ethylhexyl triazone;

[0358] The second UV-B filter is octyl salicylate;

[0359] The third UV-B filter is diethylhexyl butyramido triazone; and

[0360] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0361] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

[0362] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 16% to about 18% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 16.5% to about 17.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0363] In certain embodiments, the sunscreen composition comprises:

[0364] The UV-A filter is butyl methoxydibenzoylmethane;

[0365] The first UV-B filter is isoamyl p-methoxycinnamate;

[0366] The second UV-B filter is octyl salicylate;

[0367] The third UV-B filter is diethylhexyl butyramido triazone; and

[0368] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0369] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

[0370] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 16% to about 18% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 16.5% to about 17.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0371] In certain embodiments, the sunscreen composition comprises:

[0372] The UV-A filter is butyl methoxydibenzoylmethane;

[0373] The first UV-B filter is ethylhexyl triazone;

[0374] The second UV-B filter is octyl salicylate;

[0375] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0376] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0377] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0378] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 18% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 19% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0379] In certain embodiments, the sunscreen composition comprises:

[0380] The UV-A filter is butyl methoxydibenzoylmethane;

[0381] The first UV-B filter is ethylhexyl triazone;

[0382] The second UV-B filter is octyl salicylate;

[0383] The third UV-B filter is diethylhexyl butyramido triazone; and

[0384] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0385] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

[0386] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 26% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0387] In certain embodiments, the sunscreen composition comprises:

[0388] The UV-A filter is butyl methoxydibenzoylmethane;

[0389] The first UV-B filter is isoamyl p-methoxycinnamate;

[0390] The second UV-B filter is octyl salicylate;

[0391] The third UV-B filter is diethylhexyl butyramido triazone; and

[0392] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0393] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0394] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 26% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0395] In certain embodiments, the sunscreen composition comprises:

[0396] The UV-A filter is butyl methoxydibenzoylmethane;

[0397] The first UV-B filter is ethylhexyl triazone;

[0398] The second UV-B filter is octyl salicylate;

[0399] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0400] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0401] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0402] Wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

[0403] In certain embodiments, the sunscreen composition comprises:

[0404] The UV-A filter is butyl methoxydibenzoylmethane;

[0405] The first UV-B filter is ethylhexyl triazone;

[0406] The second UV-B filter is octyl salicylate;

[0407] The third UV-B filter is diethylhexyl butyramido triazone; and

[0408] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0409] The mass ratio of UV-A filter to UV-B filter to broadband filter is 9:20:7, and

[0410] Wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

[0411] In certain embodiments, the sunscreen composition comprises:

[0412] The UV-A filter is butyl methoxydibenzoylmethane;

[0413] The first UV-B filter is isoamyl p-methoxycinnamate;

[0414] The second UV-B filter is octyl salicylate;

[0415] The third UV-B filter is diethylhexyl butyramido triazone; and

[0416] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0417] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0418] Wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

[0419] In certain embodiments, the sunscreen composition comprises:

[0420] The UV-A filter is butyl methoxydibenzoylmethane;

[0421] The first UV-B filter is ethylhexyl triazone;

[0422] The second UV-B filter is octyl salicylate;

[0423] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0424] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0425] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0426] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 22.5% to about 25.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 23% to 25% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0427] In certain embodiments, the sunscreen composition comprises:

[0428] The UV-A filter is butyl methoxydibenzoylmethane;

[0429] The first UV-B filter is ethylhexyl triazone;

[0430] The second UV-B filter is octyl salicylate;

[0431] The third UV-B filter is diethylhexyl butyramido triazone; and

[0432] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0433] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9: 20: 7.

[0434] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 22.5% to about 25.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 23% to 25% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0435] In certain embodiments, the sunscreen composition comprises:

[0436] The UV-A filter is butyl methoxydibenzoylmethane;

[0437] The first UV-B filter is isoamyl p-methoxycinnamate;

[0438] The second UV-B filter is octyl salicylate;

[0439] The third UV-B filter is diethylhexyl butyramido triazone; and

[0440] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0441] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0442] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 22.5% to about 25.5% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 23% to 25% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0443] In certain embodiments, the sunscreen composition comprises:

[0444] The UV-A filter is butyl methoxydibenzoylmethane;

[0445] The first UV-B filter is ethylhexyl triazone;

[0446] The second UV-B filter is octyl salicylate;

[0447] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0448] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0449] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0450] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0451] In certain embodiments, the sunscreen composition comprises:

[0452] The UV-A filter is butyl methoxydibenzoylmethane;

[0453] The first UV-B filter is ethylhexyl triazone;

[0454] The second UV-B filter is octyl salicylate;

[0455] The third UV-B filter is diethylhexyl butyramido triazone; and

[0456] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0457] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

[0458] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0459] In certain embodiments, the sunscreen composition comprises:

[0460] The UV-A filter is butyl methoxydibenzoylmethane;

[0461] The first UV-B filter is isoamyl p-methoxycinnamate;

[0462] The second UV-B filter is octyl salicylate;

[0463] The third UV-B filter is diethylhexyl butyramido triazone; and

[0464] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0465] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

[0466] The composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, such as a mixture of about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate, for example, a mixture of about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0467] In certain embodiments, the sunscreen composition comprises:

[0468] The UV-A filter is butyl methoxydibenzoylmethane;

[0469] The first UV-B filter is ethylhexyl triazone;

[0470] The second UV-B filter is octyl salicylate;

[0471] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0472] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0473] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

[0474] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 18% to about 22% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 20% to about 21% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0475] In certain embodiments, the sunscreen composition comprises:

[0476] The UV-A filter is butyl methoxydibenzoylmethane;

[0477] The first UV-B filter is isoamyl p-methoxycinnamate;

[0478] The second UV-B filter is octyl salicylate;

[0479] The third UV-B filter is diethylhexyl butyramido triazone; and

[0480] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0481] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

[0482] The composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as a mixture of about 18% to about 22% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, for example, a mixture of about 20% to about 21% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.

[0483] In certain embodiments, the sunscreen composition comprises:

[0484] The UV-A filter is butyl methoxydibenzoylmethane;

[0485] The first UV-B filter is ethylhexyl triazone;

[0486] The second UV-B filter is octyl salicylate;

[0487] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0488] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0489] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

[0490] The composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as a mixture of about 29% to about 33% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate, for example, a mixture of about 30% to about 32% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

[0491] In certain embodiments, the sunscreen composition comprises:

[0492] The UV-A filter is butyl methoxydibenzoylmethane;

[0493] The first UV-B filter is isoamyl p-methoxycinnamate;

[0494] The second UV-B filter is octyl salicylate;

[0495] The third UV-B filter is diethylhexyl butyramido triazone; and

[0496] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0497] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

[0498] The composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as a mixture of about 29% to about 33% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate, for example, a mixture of about 30% to about 32% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

[0499] In certain embodiments, the sunscreen composition comprises:

[0500] The UV-A filter is butyl methoxydibenzoylmethane;

[0501] The first UV-B filter is ethylhexyl triazone;

[0502] The second UV-B filter is octyl salicylate;

[0503] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0504] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0505] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8, and

[0506] The composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

[0507] In certain embodiments, the sunscreen composition comprises:

[0508] The UV-A filter is butyl methoxydibenzoylmethane;

[0509] The first UV-B filter is ethylhexyl triazone;

[0510] The second UV-B filter is octyl salicylate;

[0511] The third UV-B filter is diethylhexyl butyramido triazone; and

[0512] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0513] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

[0514] The composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

[0515] In certain embodiments, the sunscreen composition comprises:

[0516] The UV-A filter is butyl methoxydibenzoylmethane;

[0517] The first UV-B filter is isoamyl p-methoxycinnamate;

[0518] The second UV-B filter is octyl salicylate;

[0519] The third UV-B filter is diethylhexyl butyramido triazone; and

[0520] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0521] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8, and

[0522] The composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

[0523] In certain embodiments, the sunscreen composition comprises:

[0524] The UV-A filter is butyl methoxydibenzoylmethane;

[0525] The first UV-B filter is ethylhexyl triazone;

[0526] The second UV-B filter is octyl salicylate;

[0527] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0528] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0529] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7, and

[0530] Wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, for example about 18% to about 19% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0531] In certain embodiments, the sunscreen composition comprises:

[0532] The UV-A filter is butyl methoxydibenzoylmethane;

[0533] The first UV-B filter is isoamyl p-methoxycinnamate;

[0534] The second UV-B filter is octyl salicylate;

[0535] The third UV-B filter is diethylhexyl butyramido triazone; and

[0536] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0537] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7, and

[0538] Wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, for example about 18% to about 19% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0539] In certain embodiments, the sunscreen composition comprises:

[0540] The UV-A filter is butyl methoxydibenzoylmethane;

[0541] The first UV-B filter is ethylhexyl triazone;

[0542] The second UV-B filter is octyl salicylate;

[0543] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0544] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0545] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8, and

[0546] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 20% to about 23% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 21% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0547] In certain embodiments, the sunscreen composition comprises:

[0548] The UV-A filter is butyl methoxydibenzoylmethane;

[0549] The first UV-B filter is isoamyl p-methoxycinnamate;

[0550] The second UV-B filter is octyl salicylate;

[0551] The third UV-B filter is diethylhexyl butyramido triazone; and

[0552] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0553] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8, and

[0554] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 20% to about 23% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 21% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0555] In certain embodiments, the sunscreen composition comprises:

[0556] The UV-A filter is butyl methoxydibenzoylmethane;

[0557] The first UV-B filter is ethylhexyl triazone;

[0558] The second UV-B filter is octyl salicylate;

[0559] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0560] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0561] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0562] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 24% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 25% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0563] In certain embodiments, the sunscreen composition comprises:

[0564] The UV-A filter is butyl methoxydibenzoylmethane;

[0565] The first UV-B filter is isoamyl p-methoxycinnamate;

[0566] The second UV-B filter is octyl salicylate;

[0567] The third UV-B filter is diethylhexyl butyramido triazone; and

[0568] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0569] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0570] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 24% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 25% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0571] In certain embodiments, the sunscreen composition comprises:

[0572] The UV-A filter is butyl methoxydibenzoylmethane;

[0573] The first UV-B filter is ethylhexyl triazone;

[0574] The second UV-B filter is octyl salicylate;

[0575] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0576] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0577] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0578] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0579] In certain embodiments, the sunscreen composition comprises:

[0580] The UV-A filter is butyl methoxydibenzoylmethane;

[0581] The first UV-B filter is ethylhexyl triazone;

[0582] The second UV-B filter is octyl salicylate;

[0583] The third UV-B filter is diethylhexyl butyramido triazone; and

[0584] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0585] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

[0586] Wherein the composition further comprises dibutyl adipate and decyl cocoate, such as about 31% to about 34% of a mixture of dibutyl adipate and decyl cocoate, for example, about 32% to about 33% of a mixture of dibutyl adipate and decyl cocoate.

[0587] In certain embodiments, the sunscreen composition comprises:

[0588] The UV-A filter is butyl methoxydibenzoylmethane;

[0589] The first UV-B filter is isoamyl p-methoxycinnamate;

[0590] The second UV-B filter is octyl salicylate;

[0591] The third UV-B filter is diethylhexyl butyramido triazone; and

[0592] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0593] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0594] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0595] In certain embodiments, the sunscreen composition comprises:

[0596] The UV-A filter is butyl methoxydibenzoylmethane;

[0597] The first UV-B filter is ethylhexyl triazone;

[0598] The second UV-B filter is octyl salicylate;

[0599] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0600] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0601] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0602] The composition further comprises diisopropyl sebacate, decyl cocoate and diisopropyl adipate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate and diisopropyl adipate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, decyl cocoate and diisopropyl adipate.

[0603] In certain embodiments, the sunscreen composition comprises:

[0604] The UV-A filter is butyl methoxydibenzoylmethane;

[0605] The first UV-B filter is isoamyl p-methoxycinnamate;

[0606] The second UV-B filter is octyl salicylate;

[0607] The third UV-B filter is diethylhexyl butyramido triazone; and

[0608] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0609] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

[0610] The composition further comprises diisopropyl sebacate, decyl cocoate and diisopropyl adipate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate and diisopropyl adipate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, decyl cocoate and diisopropyl adipate.

[0611] In certain embodiments, the sunscreen composition comprises:

[0612] The UV-A filter is butyl methoxydibenzoylmethane;

[0613] The first UV-B filter is ethylhexyl triazone;

[0614] The second UV-B filter is octyl salicylate;

[0615] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0616] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0617] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

[0618] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 25% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0619] In certain embodiments, the sunscreen composition comprises:

[0620] The UV-A filter is butyl methoxydibenzoylmethane;

[0621] The first UV-B filter is ethylhexyl triazone;

[0622] The second UV-B filter is octyl salicylate;

[0623] The third UV-B filter is diethylhexyl butyramido triazone; and

[0624] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0625] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8, and

[0626] Wherein the composition further comprises dibutyl adipate, such as from about 36% to about 39% dibutyl adipate, for example from about 37% to about 38% dibutyl adipate.

[0627] In certain embodiments, the sunscreen composition comprises:

[0628] The UV-A filter is butyl methoxydibenzoylmethane;

[0629] The first UV-B filter is isoamyl p-methoxycinnamate;

[0630] The second UV-B filter is octyl salicylate;

[0631] The third UV-B filter is diethylhexyl butyramido triazone; and

[0632] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0633] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

[0634] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 25% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0635] In certain embodiments, the sunscreen composition comprises:

[0636] The UV-A filter is butyl methoxydibenzoylmethane;

[0637] The first UV-B filter is ethylhexyl triazone;

[0638] The second UV-B filter is octyl salicylate;

[0639] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0640] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0641] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

[0642] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0643] In certain embodiments, the sunscreen composition comprises:

[0644] The UV-A filter is butyl methoxydibenzoylmethane;

[0645] The first UV-B filter is ethylhexyl triazone;

[0646] The second UV-B filter is octyl salicylate;

[0647] The third UV-B filter is diethylhexyl butyramido triazone; and

[0648] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0649] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8, and

[0650] Wherein the composition further comprises dibutyl adipate and decyl cocoate, such as about 31% to about 34% of a mixture of dibutyl adipate and decyl cocoate, for example, about 32% to about 33% of a mixture of dibutyl adipate and decyl cocoate.

[0651] In certain embodiments, the sunscreen composition comprises:

[0652] The UV-A filter is butyl methoxydibenzoylmethane;

[0653] The first UV-B filter is isoamyl p-methoxycinnamate;

[0654] The second UV-B filter is octyl salicylate;

[0655] The third UV-B filter is diethylhexyl butyramido triazone; and

[0656] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0657] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8, and

[0658] The composition further comprises diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, such as about 25% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate and decyl cocoate.

[0659] In certain embodiments, the sunscreen composition is an emulsion. In certain embodiments, the composition is an oil-in-water emulsion. In certain embodiments, the composition is a water-in-oil emulsion. In certain embodiments, the sunscreen composition is a spray. In certain embodiments, the sunscreen composition is an oil. In certain embodiments, the sunscreen composition is a lotion. In certain embodiments, the sunscreen composition is a cream. In certain embodiments, the sunscreen composition is a gel. In certain embodiments, the sunscreen composition is a butter. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a stick. In certain embodiments, the sunscreen composition is a powder. In certain embodiments, the sunscreen composition is a wipe. In certain embodiments, the sunscreen composition is a towel. In certain embodiments, the sunscreen composition is a shower gel. In certain embodiments, the sunscreen composition is a shampoo. In certain embodiments, the sunscreen composition is a mist. In certain embodiments, the sunscreen composition is a pour-on compact. In certain embodiments, the sunscreen composition is a solution. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a liquid. In certain embodiments, the sunscreen composition is a solid. In certain embodiments, the sunscreen composition is an emulsion. In certain embodiments, the sunscreen composition is a suspension. In certain embodiments, the sunscreen composition is a microemulsion. In certain embodiments, the sunscreen composition is a dispersion. In certain embodiments, the sunscreen composition is a microencapsulated product. In certain embodiments, the sunscreen composition is a cream. In certain embodiments, the sunscreen composition is a tonic. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is a skin agent. In certain embodiments, the sunscreen composition is a soap. In certain embodiments, the sunscreen composition is an aerosol. In certain embodiments, the sunscreen composition is a mousse. In certain embodiments, the sunscreen composition is a wax. In certain embodiments, the sunscreen composition is a pomade. In certain embodiments, the sunscreen composition is a spritz. In certain embodiments, the sunscreen composition is a varnish. In certain embodiments, the sunscreen composition is a serum. In certain embodiments, the sunscreen composition is a powder. In certain embodiments, the sunscreen composition is a pencil. In certain embodiments, the sunscreen composition is a blush. In certain embodiments, the sunscreen composition is a highlighter. In certain embodiments, the sunscreen composition is a contour powder. In certain embodiments, the sunscreen composition is a concealer.

[0660] The vehicle may include an aqueous phase, an oil phase, an alcohol, a silicone phase, or a mixture thereof. Cosmetically acceptable vehicles may also include emulsions. Non-limiting examples of suitable emulsions include water-in-oil emulsions, oil-in-water emulsions, silicone-in-water emulsions, water-in-silicone emulsions, wax-in-water emulsions, water-in-oil-in-water triple emulsions, etc., with the appearance of a cream, a gel, or a microemulsion. The emulsion may include an emulsifier, such as a nonionic, anionic, or amphoteric surfactant.

[0661] In one embodiment, the oil phase of the emulsion has one or more organic compounds including emollients; humectants (such as butylene glycol, propylene glycol, methyl glucitol-20 and glycerin); other water-dispersible or water-soluble components including thickeners such as veegum or hydroxyalkyl cellulose; gelling agents such as high MW polyacrylic acid, i.e., CARBOPOL 934; and mixtures thereof. The emulsion may have one or more emulsifiers capable of emulsifying the various components present in the composition.

[0662] Suitable compounds for the oil phase include, but are not limited to, vegetable oils; esters such as octyl palmitate, isopropyl myristate and isopropyl palmitate; ethers such as dicaprylyl ether; fatty alcohols such as cetyl alcohol, stearyl alcohol and phenylethyl alcohol; isoparaffins such as isooctane, isododecane and isohexadecane; silicone oils such as dimethylsiloxane, cyclic silicones and polysiloxanes; hydrocarbon oils such as mineral oil, paraffin oil, isoeicosane and polyisobutene; natural or synthetic waxes; and the like. Suitable hydrophobic hydrocarbon oils may be saturated or unsaturated, have aliphatic characteristics and be straight or branched or contain alicyclic or aromatic rings. The oil-containing phase may be composed of a single oil or a mixture of different oils.

[0663] Hydrogen oils include those hydrocarbon oils having 6-20 carbon atoms, and in one embodiment, having more than 10-16 carbon atoms. Representative hydrocarbons include decane, dodecane, tetradecane, tridecane, and C 8-20 Isoparaffins. Paraffinic hydrocarbons are available from Exxon under the ISOPARS trademark and from Permethyl Corporation. In addition, C 8-20 Paraffinic hydrocarbons, such as C 99A.TM. manufactured by Permethyl Corporation. 12 Isoparaffin (isododecane) is suitable. Commercially available C 16 Isoparaffins, such as isohexadecane (with the trade name Permethyl) are also suitable. In one embodiment, examples of volatile hydrocarbons include polydecanes such as isododecane and isodecane, including, for example, Permethyl-99A (Presperse Inc.) and C 7 -C 8 to C 12-C 15 Isoparaffins, such as the Isopar series available from ExxonMobil Chemical Company. A representative hydrocarbon solvent is isododecane.

[0664] The oil phase may include one or more waxes including, for example, rice wax, carnauba wax, cocoa wax, candelilla wax, montan wax, sugar cane wax, ozokerite wax, polyethylene wax, Fischer-Tropsch wax, beeswax, microcrystalline wax, silicone wax, fluorinated wax, and any combination thereof.

[0665] Non-limiting emulsifiers include emulsifying waxes, emulsifying polyols, polyether polyols, polyethers, polyols of monoesters or diesters, ethylene glycol monostearate, glyceryl monostearate, glyceryl distearate, silicone-containing emulsifiers, soybean alcohol, fatty alcohols such as cetyl alcohol, acrylates, fatty acids such as stearic acid, fatty acid salts, and mixtures thereof. In one embodiment, the emulsifier includes soybean sterols, cetyl alcohol, stearic acid, emulsifying waxes, acrylates, silicone-containing emulsifiers, and mixtures thereof. Other specific emulsifiers that can be used in the compositions of the present invention include, but are not limited to, one or more of the following: C 10-30 Alkyl acrylate crosspolymer; dimethicone PEG-7 isostearic acid, acrylamide copolymer; mineral oil; sorbitan esters; polyglyceryl-3-diisostearate; sorbitan monostearate, sorbitan tristearate, sorbitan sesquioleate, sorbitan monooleate; glyceryl esters such as glyceryl monostearate and glyceryl monooleate; polyoxyethylene phenols such as polyoxyethylene octylphenol and polyoxyethylene nonylphenol; polyoxyethylene ethers such as polyoxyethylene cetyl ether and polyoxyethylene stearyl ether; polyoxyethylene glycol esters; polyoxyethylene sorbitan esters; dimethicone copolyol; polyglyceryl esters such as polyglyceryl-3-diisostearate; glyceryl laurate; steareth-2, steareth-10, and steareth-20, to name a few. Additional emulsifiers are provided in the INCI Ingredient Dictionary and Handbook, 11th Edition, 2006, the disclosure of which is incorporated herein by reference.

[0666] These emulsifiers will generally be present in the composition in amounts of about 0.001 wt % to about 10 wt %, specifically about 0.01 wt % to about 5 wt %, and more specifically in one embodiment about 0.1 wt % to about 3 wt %.

[0667] The oil phase may include one or more volatile and / or non-volatile silicone oils. Volatile silicones include cyclic and linear volatile dimethyl siloxane silicones. In one embodiment, the volatile silicone may include cyclodimethylsiloxane, including tetramer (D 4 ), pentamer (D5 and hexamer (D 6 ) cyclomethicone or mixtures thereof. Volatile cyclomethicone-hexamethylcyclotrisiloxane, octamethyl-cyclotetrasiloxane and decamethyl-cyclopentasiloxane are particularly mentioned. Suitable dimethylsiloxanes are available from Dow Corning under the name Dow Corning 200 Fluid and have a viscosity range of 0.65 to 600,000 centistokes or higher. Exemplary non-polar volatile liquid silicone oils are disclosed in U.S. Pat. No. 4,781,917, which is incorporated herein by reference in its entirety. Additional volatile silicone materials are described in Todd et al., "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toiletries, 91:27-32 (1976), which is incorporated herein by reference in its entirety. The viscosity of linear volatile silicones is generally less than about 5 centistokes at 25°C, while the viscosity of cyclic silicones is less than about 10 centistokes at 25°C. Examples of volatile silicones of varying viscosities include Dow Corning 200, Dow Corning 244, Dow Corning 245, Dow Corning 344, and Dow Corning 345 (Dow Corning); SF-1204 and SF-1202 silicone fluids (General Electric Silicones), GE 7207 and 7158 (General Electric); and SWS-03314 (SWS Silicones Corp.). Linear volatile silicones include low molecular weight polydimethylsiloxane compounds such as hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, and dodecamethylpentasiloxane, to name a few.

[0668] Non-volatile silicone oils will typically include polyalkylsiloxanes, polyarylsiloxanes, polyalkylarylsiloxanes, or mixtures thereof. In one embodiment, polydimethylsiloxane is a non-volatile silicone oil. The viscosity of non-volatile silicone oils is typically about 10 centistokes to about 60,000 centistokes at 25°C, between about 10 centistokes and about 10,000 centistokes in one embodiment, and still more between about 10 centistokes and about 500 centistokes in one embodiment; and its boiling point is greater than 250°C at ambient pressure. Non-limiting examples include dimethylpolysiloxane (dimethylsiloxane), phenyltrimethylsiloxane, and diphenyldimethylsiloxane. Volatile and non-volatile silicone oils may be optionally substituted with various functional groups, such as alkyl, aryl, amine, vinyl, hydroxyl, haloalkyl, alkylaryl, and acrylate groups, to name a few.

[0669] Water-in-silicone emulsions can be emulsified with nonionic surfactants (emulsifiers), such as polydiorganosiloxane-polyoxyalkylene block copolymers, including those disclosed in U.S. Pat. No. 4,122,029, the disclosure of which is incorporated herein by reference. These emulsifiers typically include a polydiorganosiloxane backbone, typically a polydimethylsiloxane having side chains including -(EO)m- and / or -(PO)n- groups, wherein EO is ethyleneoxy and PO is 1,2-propyleneoxy, the side chains typically being replaced by hydrogen or lower alkyl groups (e.g., C 1-6 , usually C 1-3 ) capped or end-capped. Other suitable water-in-silicone emulsifiers are disclosed in U.S. Pat. No. 6,685,952, the disclosure of which is incorporated herein by reference. Commercially available water-in-silicone emulsifiers include those available from Dow Corning under the trade names 3225C and 5225C FORMULATIONAID; SILICONE SF-1528 available from General Electric; ABIL EM 90 and EM 97 available from Goldschmidt Chemical Company (Hopewell, Va.); and the SILWET series of emulsifiers sold by OSI Specialties, Inc., Compton, VA.

[0670] Examples of water-in-silicone emulsifiers include, but are not limited to, dimethicone PEG 10 / 15 crosspolymer, dimethicone copolyol, cetyl dimethicone copolyol, PEG-15 lauryl dimethicone crosspolymer, lauryl methicone crosspolymer, cyclomethicone and dimethicone copolyol, dimethicone copolyol (and) caprylyl / decyl triglyceride, polyglyceryl-4 isostearate (and) cetyl dimethicone copolyol (and) hexyl laurate, and dimethicone copolyol (and) cyclopentasiloxane. In one embodiment, examples of water-in-silicone emulsifiers include, but are not limited to, PEG / PPG-18 / 18 dimethicone (trade name 5225C of Dow Corning), PEG / PPG-19 / 19 dimethicone (trade name BY25-337 of Dow Corning), cetyl PEG / PPG-10 / 1 dimethicone (trade name Abil EM-90 of Goldschmidt Chemical Corporation), PEG-12 dimethicone (trade name SF 1288 of General Electric), lauryl PEG / PPG-18 / 18 methyl siloxane (trade name 5200 FORMULATION 90 of Dow Corning), and PEG / PPG-10 / 12 dimethicone (trade name SF 1288 of General Electric). AID), PEG-12 Dimethicone Crosspolymer (trade name 9010 and 9011 Silicone Elastomer Blend from Dow Corning), PEG-10 Dimethicone Crosspolymer (trade name KSG-20 from Shin-Etsu), Dimethicone PEG-10 / 15 Crosspolymer (trade name KSG-210 from Shin-Etsu), and Dimethicone PEG-7 Isostearate.

[0671] The water-in-silicone emulsifier will generally be present in the composition in an amount of about 0.001 wt % to about 10 wt %, specifically about 0.01 wt % to about 5 wt % and more specifically less than 1 wt %.

[0672] The aqueous phase of the emulsion may contain one or more additional solvents, including lower alcohols, such as ethanol, isopropanol, etc. The volatile solvent may also be a cosmetically acceptable ester, such as butyl acetate or ethyl acetate; a ketone, such as acetone or ethyl methyl ketone; and the like.

[0673] Based on the total weight of the emulsion, the oil-containing phase will typically include about 10% to about 99% by weight, in one embodiment about 20% to about 85% by weight, and more in one embodiment about 30% to about 70% by weight of the total emulsion, and the aqueous phase will typically include about 1% to about 90% by weight, in one embodiment about 5% to about 70% by weight, and more in one embodiment about 20% to about 60% by weight of the total emulsion. The aqueous phase will typically include about 25% to about 100% by weight, more typically about 50% to about 95% by weight of water.

[0674] The composition may comprise liposomes. The liposomes may include other additives or substances, and / or may be modified to more specifically reach or remain at a certain site after administration.

[0675] The composition may optionally include other cosmetic actives and excipients that will be apparent to one skilled in the art, including but not limited to fillers, emulsifiers, antioxidants, surfactants, film formers, chelating agents, gelling agents, thickeners, emollients, humectants, moisturizers, vitamins, minerals, viscosity and / or rheology modifiers, sunscreens, keratinizers, depigmenting agents, retinol, hormonal compounds, alpha-hydroxy acids, alpha-keto acids, antimycobacterial agents, antifungal agents, antimicrobial agents, antiviral agents. , analgesics, lipid compounds, antiallergic agents, H1 or H2 antihistamines, anti-inflammatory agents, anti-irritants, antineoplastics, immune system enhancers, immune system suppressants, anti-alveolar agents, anesthetics, antibacterial agents, insect repellents, skin cooling compounds, skin care agents, skin penetration enhancers, exfoliants, lubricants, fragrances, colorants, depigmenting agents, hypopigmenting agents, preservatives (e.g., DMDM ​​hydantoin / iodopropynyl butyl carbonate), stabilizers, pharmaceutical preparations, photostabilizers, neutralizers (e.g., triethanolamine), and mixtures thereof. In addition to the foregoing, the cosmetic composition of the present invention may contain any other compound for treating skin disorders.

[0676] Examples of film formers include poly C10-30 alkyl acrylate and triethylpentanediol / adipic acid / glycerin crosspolymer.

[0677] In certain embodiments, the sunscreen composition may further include other cosmetic ingredients, such as, but not limited to, humectants, emollients, moisturizers, anti-wrinkle ingredients, concealers, matte polishes, pigments, colorants, proteins, antioxidants, contour powders, chelating agents, emulsifiers, ultraviolet (UV) absorbers, oil absorbers, antifoaming agents, anti-adhesive agents, thickeners, fragrances, preservatives, antimicrobial agents, antifungal agents, neutralizers, vitamins, plasticizers, cohesive agents, alkalizing and acidifying agents, fillers, solvents, and mixtures thereof. Those skilled in the art will appreciate that any other cosmetically acceptable ingredients, i.e., those included in the 3rd edition of the CFTA Cosmetic Ingredient Dictionary, may be used.

[0678] The composition can contain additional ingredients, such as alkalizers, emulsifiers, emollients, plasticizers, preservatives, wetting agents, moisturizers, solvents and tonicity agents or active ingredients suitable for providing anti-aging benefits. The example of preferred additional ingredients includes glycerol. Thickening agents, such as gelling agents, can also be used. Examples include bentone, triglycerides, aluminum stearate, C18-C36 acid glycol esters, triphein, monostearate glyceryl, alginates, carbomers, cellulose, glue, carrageenan, starch or silicates. Fillers can also be optionally added in an amount of about 1% to about 20%, preferably about 1% to about 10%. The example of filler includes silicon dioxide, PMMA, nylon, aluminum oxide, barium sulfate or any other filler commonly used in such compositions.

[0679] The composition may also contain at least one cosmetic active ingredient and / or at least one dermatological active ingredient, i.e., an agent having a beneficial effect on the skin. The loading of such active ingredients may be achieved in any manner known to those skilled in the art. The composition may include other whitening or lightening agents that further include pigments or other reflective materials to hide the discoloration or treat the cause of the discoloration.

[0680] In certain embodiments, the sunscreen composition is substantially stable to sunlight. In certain embodiments, the AUC in the spectral absorption spectrum after irradiation with a solar simulator is at least 80% of the AUC in the spectral absorption spectrum before irradiation. The AUC in the spectral absorption spectrum after irradiation with a solar simulator is at least 90% of the AUC in the spectral absorption spectrum before irradiation. Sunlight stability can be measured by methods known to those skilled in the art.

[0681] In certain embodiments, the sunscreen composition is substantially water resistant. Water resistance can be measured by methods known to those skilled in the art. In certain embodiments, the composition is water resistant for 40 or 80 minutes as codified by the US Food and Drug Administration in Section 201.327(i)(7) of Volume 21 of the Code of Federal Regulations (2019).

[0682] In certain embodiments, the sunscreen composition is phase stable. As used herein, "phase stability" means maintaining interfacial stability or suspension stability or both for at least 4 weeks at each temperature of 4°C, 32-37°C, 40-45°C, 25°C. "Interfacial stability" refers to the stability to agglomeration and roughening of a discontinuous phase in a composition having two or more phases. "Suspension stability" refers to the stability to creaming and / or precipitation of a discontinuous phase, such as a solid suspended in a continuous phase.

[0683] In certain embodiments, the sunscreen composition maintains interfacial stability and suspension stability for at least 4 weeks at each of 4° C., 32-37° C., 40-45° C., and 25° C. To evaluate such stability conditions, the composition can be filled into a container of appropriate size, such as a clear 4-ounce glass jar, in which the composition is fully visible.

[0684] The interfacial stability of a sunscreen composition can be assessed visually and is considered unstable if at least two distinct immiscible phases of the composition are observed, as is well known in the art.

[0685] In certain embodiments, the sunscreen composition is not phase stable and is, for example, shaken prior to use.

[0686] As is also known in the art, the suspension stability of the sunscreen composition can be assessed visually or tactilely, and if different separations or gradients of color, opacity, crispness, or other indicators of non-uniformity between different regions of the sample (i.e., top and bottom or other different regions) are observed, the suspension stability is considered unstable. Alternatively, the suspension stability of the composition can be assessed by, but not limited to, Brookfield viscosity, and if there is a significant change (e.g., 5% or 10% or 20%) in viscosity measurements between different regions in the sample (i.e., top and bottom or other different regions), the suspension stability is considered unstable. Brookfield viscosity can be measured with a Brookfield laboratory viscometer from AMETEK Inc., Middleboro, Mass., using settings, spindles, and speeds appropriate for the viscosity of the composition.

[0687] Overall phase stability can also be assessed by other techniques known in the art, such as by analytical chemical testing to determine significant changes in chemical composition between different regions (ie, top and bottom or other distinct regions) in a sample.

[0688] The sunscreen composition can be used by topical application to the skin. The method for application may include spraying, smearing, wiping or applying the composition directly to the skin.

[0689] Sunscreen compositions can be prepared using mixing and blending methods that are well established in the sunscreen and cosmetic arts. In one embodiment, the composition is produced by: preparing an oil phase by mixing a UV absorbing compound with optional oil-soluble or oil-miscible ingredients; and preparing an aqueous phase by mixing water with optional water-soluble or water-miscible ingredients. The oil phase and the aqueous phase can then be mixed in a manner sufficient to disperse the oil phase substantially uniformly in the aqueous phase, such that the aqueous phase persists and the oil phase does not persist.

[0690] The weight percentage of the aqueous phase included in the composition can range from about 30% to about 85%, such as from about 35% to about 75%, such as from about 40% to about 70%. The percentage of water by weight in the aqueous phase can be about 60% or greater, such as about 70% or greater, such as about 90% or greater.

[0691] The composition may be combined with a "cosmetically acceptable topical carrier," ie, a carrier for topical use which is capable of containing other ingredients dispersed or dissolved therein and which has acceptable properties rendering it safe for topical use.

[0692] The cosmetically acceptable topical carrier may optionally include various additional oil-soluble materials and / or water-soluble materials conventionally used in compositions for application to the skin at levels determined in the art. For example, surfactants, emulsifiers, beading agents or opacifiers, thickeners, emollients, conditioners, humectants, chelating agents, exfoliants, preservatives, pH adjusters, and additives that enhance the appearance, feel, or flavor of the composition, such as colorants, fragrances, tactile modifiers, and the like may be included.

[0693] In certain embodiments, the composition comprises a pigment suitable for providing color or hiding ability. The pigment can be suitable for one in a colored cosmetic product, comprising a composition for applying to hair, nails and / or skin, particularly facial. Color cosmetic compositions include but are not limited to foundation, concealer, primer, rouge, mascara, eye shadow, eyeliner, lipstick, nail gloss and tinted moisturizer. The pigment suitable for providing color or hiding ability can be made of iron oxide, which comprises red and yellow iron oxide, titanium dioxide, super ocean color and chromium or chromium hydroxide color and mixtures thereof. The pigment can be a lake pigment precipitated onto an inert adhesive such as an insoluble salt, such as an organic dye, such as azo, indigo, triphenylmethane, anthraquinone and a xanthine dye named as D&C and FD&C blue, brown, green, orange, red, yellow, etc. The example of a lake pigment comprises red #6, red #7, yellow #5, violet #2 and blue #1. The pigment can be a coherent pigment. Examples of coherent pigments include those containing a mica base, a bismuth oxychloride base, and a silica base, such as mica / bismuth oxychloride / iron oxide pigments commercially available as CHROMALITE pigments (BASF), titanium dioxide and / or iron oxide coated onto mica such as the commercially available FLAMENCO pigments (BASF), mica / titanium dioxide / iron oxide pigments including commercially available KTZ pigments (Kobo products), CELLINI pearl pigments (BASF), and borosilicate-containing pigments such as REFLECKS pigments (BASF).

[0694] In one embodiment, the composition includes a humectant, such as glycol, glycerin, or propylene glycol. The composition can include, for example, at least about 1.0% by weight of a humectant.

[0695] The composition may further include one or more other cosmetically acceptable active agents including, for example, anti-acne agents, oil control agents, antimicrobial agents, antifungal agents, antiparasitic agents (including anti-monkey poisons), external analgesics, antioxidants, moisturizers, nutrients, vitamins, energy enhancers, antiperspirants, astringents, deodorants, firming agents, anti-callousing agents and agents for skin conditioning, tanning, anti-wrinkle and anti-dark spot.

[0696] In certain embodiments, the composition is intended for use as a non-therapeutic treatment. In certain embodiments, the composition is an article intended to be rubbed, poured, splashed, or sprayed onto, introduced into, or otherwise applied to the human body for cleansing, beautifying, enhancing attractiveness, or altering appearance under the US FD&C Act, § 201(i).

[0697] Amounts of other cosmetic actives may range from about 0.001% to about 20% by weight of the composition, for example from about 0.005% to about 10% by weight of the composition, such as from about 0.01% to about 5% by weight of the composition.

[0698] According to some aspects, the sunscreen formulations described herein are ecologically comparable compositions. For example, the sunscreen formulations are compatible with biological life and are harmless to marine ecosystems (particularly for tropical environments with coral reefs). Specifically, the sunscreen formulations do not contain components that inhibit cell growth or cell replication in marine environments. In some instances, this can be achieved by the following sunscreen formulations: no bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT), cinnamate, benzophenone, camphor derivatives, titanium oxide, tea tree essential oil, blue flower extract, Indian bamboo stem extract (BambousaArundinacea extract), shea butter (Karitè), animal-derived fat, Ali root oil, tocopheryl acetate, tocopherol, retinol, polyphenolic compounds extracted from green tea, or mixtures thereof. In some aspects, the sunscreen formulation can include diisopropyl sebacate, dimethylmethoxychromanol, gluconolactone, potassium sorbate, dimethylmethoxychromanol, decyl cocoate, pentylene glycol, dimethicone, hydrolyzed citrus aurantium fruit extract.

[0699] Exemplary aspects.

[0700] The following exemplary embodiments are provided, the numbering of which should not be construed as designating a level of importance:

[0701] Aspect 1 provides a UV filter composition comprising:

[0702] Three UV-B filters;

[0703] UV-A filters; and

[0704] UV-A + UV-B broadband filters.

[0705] Aspect 2 provides a sunscreen composition comprising the UV filter composition of aspect 1.

[0706] Aspect 3 provides the sunscreen composition according to aspect 2, comprising one or more solubilizers.

[0707] Aspect 4 provides a sunscreen composition according to aspect 3, wherein the one or more solubilizers are selected from: diisopropyl sebacate, dicaprylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C12-15 alkyl benzoate and diethylhexyl succinate.

[0708] Aspect 5 provides a sunscreen composition according to any one of aspects 2 to 4, wherein:

[0709] The UV-A filter is butyl methoxydibenzoylmethane;

[0710] The first UV-B filter is ethylhexyl triazone;

[0711] The second UV-B filter is octyl salicylate;

[0712] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0713] The broadband UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0714] Aspect 6 provides a sunscreen composition according to aspect 5, wherein

[0715] The UV-A filter is butyl methoxydibenzoylmethane;

[0716] The first UV-B filter is ethylhexyl triazone;

[0717] The second UV-B filter is octyl salicylate;

[0718] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0719] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0720] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

[0721] Aspect 7 provides a sunscreen composition according to aspect 5, wherein

[0722] The UV-A filter is butyl methoxydibenzoylmethane;

[0723] The first UV-B filter is ethylhexyl triazone;

[0724] The second UV-B filter is octyl salicylate;

[0725] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0726] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0727] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2.

[0728] Aspect 8 provides a sunscreen composition according to aspect 5, wherein

[0729] The UV-A filter is butyl methoxydibenzoylmethane;

[0730] The first UV-B filter is ethylhexyl triazone;

[0731] The second UV-B filter is octyl salicylate;

[0732] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0733] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0734] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0735] Aspect 9 provides a sunscreen composition according to any one of aspects 2 to 4, wherein:

[0736] The UV-A filter is butyl methoxydibenzoylmethane;

[0737] The first UV-B filter is ethylhexyl triazone;

[0738] The second UV-B filter is octyl salicylate;

[0739] The third UV-B filter is diethylhexyl butyramido triazone; and

[0740] The broadband UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0741] Aspect 10 provides a sunscreen composition according to aspect 9, wherein

[0742] The UV-A filter is butyl methoxydibenzoylmethane;

[0743] The first UV-B filter is ethylhexyl triazone;

[0744] The second UV-B filter is octyl salicylate;

[0745] The third UV-B filter is diethylhexyl butyramido triazone; and

[0746] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0747] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2: 5.5: 1.

[0748] Aspect 11 provides a sunscreen composition according to aspect 9, wherein

[0749] The UV-A filter is butyl methoxydibenzoylmethane;

[0750] The first UV-B filter is ethylhexyl triazone;

[0751] The second UV-B filter is octyl salicylate;

[0752] The third UV-B filter is diethylhexyl butyramido triazone; and

[0753] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0754] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2.

[0755] Aspect 12 provides a sunscreen composition according to aspect 9, wherein

[0756] The UV-A filter is butyl methoxydibenzoylmethane;

[0757] The first UV-B filter is ethylhexyl triazone;

[0758] The second UV-B filter is octyl salicylate;

[0759] The third UV-B filter is diethylhexyl butyramido triazone; and

[0760] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0761] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0762] Aspect 13 provides a sunscreen composition according to any one of aspects 2 to 4, wherein:

[0763] The UV-A filter is butyl methoxydibenzoylmethane;

[0764] The first UV-B filter is isoamyl p-methoxycinnamate;

[0765] The second UV-B filter is octyl salicylate;

[0766] The third UV-B filter is diethylhexyl butyramido triazone; and

[0767] The broadband UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0768] Aspect 14 provides a sunscreen composition according to aspect 13, wherein

[0769] The UV-A filter is butyl methoxydibenzoylmethane;

[0770] The first UV-B filter is isoamyl p-methoxycinnamate;

[0771] The second UV-B filter is octyl salicylate;

[0772] The third UV-B filter is diethylhexyl butyramido triazone; and

[0773] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0774] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

[0775] Aspect 15 provides a sunscreen composition according to aspect 13, wherein

[0776] The UV-A filter is butyl methoxydibenzoylmethane;

[0777] The first UV-B filter is isoamyl p-methoxycinnamate;

[0778] The second UV-B filter is octyl salicylate;

[0779] The third UV-B filter is diethylhexyl butyramido triazone; and

[0780] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0781] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1.

[0782] Aspect 16 provides a sunscreen composition according to aspect 13, wherein

[0783] The UV-A filter is butyl methoxydibenzoylmethane;

[0784] The first UV-B filter is isoamyl p-methoxycinnamate;

[0785] The second UV-B filter is octyl salicylate;

[0786] The third UV-B filter is diethylhexyl butyramido triazone; and

[0787] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0788] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

[0789] Aspect 17 provides a sunscreen composition according to any one of aspects 2 to 16, wherein the one or more solubilizers is diisopropyl sebacate.

[0790] Aspect 18 provides a sunscreen composition according to aspect 17, wherein the composition comprises from about 8% to about 10% of diisopropyl sebacate.

[0791] Aspect 19 provides a sunscreen composition according to aspect 18, wherein the composition comprises from about 6% to about 8% of diisopropyl sebacate.

[0792] Aspect 20 provides a sunscreen composition according to aspect 5, wherein

[0793] The UV-A filter is butyl methoxydibenzoylmethane;

[0794] The first UV-B filter is ethylhexyl triazone;

[0795] The second UV-B filter is octyl salicylate;

[0796] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0797] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0798] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

[0799] Aspect 21 provides a sunscreen composition according to aspect 9, wherein

[0800] The UV-A filter is butyl methoxydibenzoylmethane;

[0801] The first UV-B filter is ethylhexyl triazone;

[0802] The second UV-B filter is octyl salicylate;

[0803] The third UV-B filter is diethylhexyl butyramido triazone; and

[0804] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0805] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

[0806] Aspect 22 provides a sunscreen composition according to aspect 13, wherein

[0807] The UV-A filter is butyl methoxydibenzoylmethane;

[0808] The first UV-B filter is isoamyl p-methoxycinnamate;

[0809] The second UV-B filter is octyl salicylate;

[0810] The third UV-B filter is diethylhexyl butyramido triazone; and

[0811] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0812] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

[0813] Aspect 23 provides a sunscreen composition according to any one of aspects 22 to 24, wherein the one or more solubilizers are diisopropyl sebacate and dicaprylyl carbonate.

[0814] Aspect 24 provides a sunscreen composition according to aspect 25, wherein the composition comprises from about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0815] Aspect 25 provides a sunscreen composition according to aspect 26, wherein the composition comprises from about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0816] Aspect 26 provides a sunscreen composition according to aspect 5, wherein

[0817] The UV-A filter is butyl methoxydibenzoylmethane;

[0818] The first UV-B filter is ethylhexyl triazone;

[0819] The second UV-B filter is octyl salicylate;

[0820] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0821] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0822] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

[0823] Aspect 27 provides a sunscreen composition according to aspect 9, wherein

[0824] The UV-A filter is butyl methoxydibenzoylmethane;

[0825] The first UV-B filter is ethylhexyl triazone;

[0826] The second UV-B filter is octyl salicylate;

[0827] The third UV-B filter is diethylhexyl butyramido triazone; and

[0828] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0829] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:17:6.

[0830] Aspect 28 provides a sunscreen composition according to aspect 13, wherein

[0831] The UV-A filter is butyl methoxydibenzoylmethane;

[0832] The first UV-B filter is isoamyl p-methoxycinnamate;

[0833] The second UV-B filter is octyl salicylate;

[0834] The third UV-B filter is diethylhexyl butyramido triazone; and

[0835] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0836] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

[0837] Aspect 29 provides a sunscreen composition according to any one of aspects 26 to 28, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.

[0838] Aspect 30 provides a sunscreen composition according to aspect 29, wherein the composition comprises about 16% to about 18% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0839] Aspect 31 provides a sunscreen composition according to aspect 30, wherein the composition comprises about 16.5% to about 17.5% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0840] Aspect 32 provides a sunscreen composition according to aspect 5, wherein

[0841] The UV-A filter is butyl methoxydibenzoylmethane;

[0842] The first UV-B filter is ethylhexyl triazone;

[0843] The second UV-B filter is octyl salicylate;

[0844] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0845] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0846] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

[0847] Aspect 33 provides a sunscreen composition according to aspect 9, wherein

[0848] The UV-A filter is butyl methoxydibenzoylmethane;

[0849] The first UV-B filter is ethylhexyl triazone;

[0850] The second UV-B filter is octyl salicylate;

[0851] The third UV-B filter is diethylhexyl butyramido triazone; and

[0852] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0853] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 3: 8.5: 2.

[0854] Aspect 34 provides a sunscreen composition according to aspect 13, wherein

[0855] The UV-A filter is butyl methoxydibenzoylmethane;

[0856] The first UV-B filter is isoamyl p-methoxycinnamate;

[0857] The second UV-B filter is octyl salicylate;

[0858] The third UV-B filter is diethylhexyl butyramido triazone; and

[0859] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0860] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

[0861] Aspect 35 provides a sunscreen composition according to any one of aspects 32 to 34, wherein the one or more solubilizing agents are decyl cocoate and diisopropyl sebacate.

[0862] Aspect 36 provides a sunscreen composition according to aspect 35, wherein the composition comprises from about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate.

[0863] Aspect 37 provides a sunscreen composition according to aspect 36, wherein the composition comprises from about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.

[0864] Aspect 38 provides a sunscreen composition according to aspect 5, wherein

[0865] The UV-A filter is butyl methoxydibenzoylmethane;

[0866] The first UV-B filter is ethylhexyl triazone;

[0867] The second UV-B filter is octyl salicylate;

[0868] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0869] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0870] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

[0871] Aspect 39 provides a sunscreen composition according to aspect 9, wherein

[0872] The UV-A filter is butyl methoxydibenzoylmethane;

[0873] The first UV-B filter is ethylhexyl triazone;

[0874] The second UV-B filter is octyl salicylate;

[0875] The third UV-B filter is diethylhexyl butyramido triazone; and

[0876] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0877] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

[0878] Aspect 40 provides a sunscreen composition according to aspect 13, wherein

[0879] The UV-A filter is butyl methoxydibenzoylmethane;

[0880] The first UV-B filter is isoamyl p-methoxycinnamate;

[0881] The second UV-B filter is octyl salicylate;

[0882] The third UV-B filter is diethylhexyl butyramido triazone; and

[0883] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0884] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

[0885] Aspect 41 provides a sunscreen composition according to any one of aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0886] Aspect 42 provides a sunscreen composition according to aspect 41, wherein the composition comprises from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0887] Aspect 43 provides a sunscreen composition according to aspect 42, wherein the composition comprises about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0888] Aspect 44 provides a sunscreen composition according to any one of aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0889] Aspect 45 provides a sunscreen composition according to aspect 44, wherein the composition comprises about 16% to about 18% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0890] Aspect 46 provides a sunscreen composition according to aspect 45, wherein the composition comprises from about 16.5% to about 17.5% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0891] Aspect 47 provides a sunscreen composition according to aspect 5, wherein

[0892] The UV-A filter is butyl methoxydibenzoylmethane;

[0893] The first UV-B filter is ethylhexyl triazone;

[0894] The second UV-B filter is octyl salicylate;

[0895] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0896] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0897] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

[0898] Aspect 48 provides a sunscreen composition according to aspect 9, wherein

[0899] The UV-A filter is butyl methoxydibenzoylmethane;

[0900] The first UV-B filter is ethylhexyl triazone;

[0901] The second UV-B filter is octyl salicylate;

[0902] The third UV-B filter is diethylhexyl butyramido triazone; and

[0903] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0904] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:4:8.

[0905] Aspect 49 provides a sunscreen composition according to aspect 13, wherein

[0906] The UV-A filter is butyl methoxydibenzoylmethane;

[0907] The first UV-B filter is isoamyl p-methoxycinnamate;

[0908] The second UV-B filter is octyl salicylate;

[0909] The third UV-B filter is diethylhexyl butyramido triazone; and

[0910] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0911] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

[0912] Aspect 50 provides a sunscreen composition according to any one of aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0913] Aspect 51 provides a sunscreen composition according to aspect 5, wherein the composition comprises about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0914] Aspect 52 provides a sunscreen composition according to aspect 51, wherein the composition comprises about 26% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[0915] Aspect 53 provides a sunscreen composition according to any one of aspects 47 to 51, wherein the one or more solubilizers are diisopropyl sebacate and diisopropyl adipate.

[0916] Aspect 54 provides a sunscreen composition according to aspect 53, wherein the composition comprises from about 32.5% to about 35 / 5% of a mixture of diisopropyl sebacate and diisopropyl adipate.

[0917] Aspect 55 provides a sunscreen composition according to aspect 54, wherein the composition comprises from about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

[0918] Aspect 56 provides a sunscreen composition according to any one of aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0919] Aspect 57 provides a sunscreen composition according to aspect 56, wherein the composition comprises from about 22.5% to about 25.5% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0920] Aspect 58 provides a sunscreen composition according to aspect 57, wherein the composition comprises from about 23% to about 25% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0921] Aspect 59 provides a sunscreen composition according to any one of aspects 47 to 49, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.

[0922] Aspect 60 provides a sunscreen composition according to aspect 59, wherein the composition comprises from about 28% to about 31% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.

[0923] Aspect 61 provides a sunscreen composition according to aspect 60, wherein the composition comprises from about 29% to about 3% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate and dibutyl adipate.

[0924] Aspect 62 provides a sunscreen composition according to aspect 5, wherein

[0925] The UV-A filter is butyl methoxydibenzoylmethane;

[0926] The first UV-B filter is ethylhexyl triazone;

[0927] The second UV-B filter is octyl salicylate;

[0928] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0929] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0930] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0931] Aspect 63 provides a sunscreen composition according to aspect 9, wherein

[0932] The UV-A filter is butyl methoxydibenzoylmethane;

[0933] The first UV-B filter is ethylhexyl triazone;

[0934] The second UV-B filter is octyl salicylate;

[0935] The third UV-B filter is diethylhexyl butyramido triazone; and

[0936] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0937] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0938] Aspect 64 provides a sunscreen composition according to aspect 13, wherein

[0939] The UV-A filter is butyl methoxydibenzoylmethane;

[0940] The first UV-B filter is isoamyl p-methoxycinnamate;

[0941] The second UV-B filter is octyl salicylate;

[0942] The third UV-B filter is diethylhexyl butyramido triazone; and

[0943] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0944] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

[0945] Aspect 65 provides a sunscreen composition according to any one of aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0946] Aspect 66 provides a sunscreen composition according to aspect 65, wherein the composition comprises from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0947] Aspect 67 provides a sunscreen composition according to aspect 66, wherein the composition comprises about 20% to about 21% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.

[0948] Aspect 68 provides a sunscreen composition according to any one of aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0949] Aspect 69 provides a sunscreen composition according to aspect 68, wherein the composition comprises from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0950] Aspect 70 provides a sunscreen composition according to aspect 69, wherein the composition comprises about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0951] Aspect 71 provides a sunscreen composition according to aspect 5, wherein

[0952] The UV-A filter is butyl methoxydibenzoylmethane;

[0953] The first UV-B filter is ethylhexyl triazone;

[0954] The second UV-B filter is octyl salicylate;

[0955] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0956] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0957] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

[0958] Aspect 72 provides a sunscreen composition according to aspect 9, wherein

[0959] The UV-A filter is butyl methoxydibenzoylmethane;

[0960] The first UV-B filter is ethylhexyl triazone;

[0961] The second UV-B filter is octyl salicylate;

[0962] The third UV-B filter is diethylhexyl butyramido triazone; and

[0963] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0964] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[0965] Aspect 73 provides a sunscreen composition according to aspect 13, wherein

[0966] The UV-A filter is butyl methoxydibenzoylmethane;

[0967] The first UV-B filter is isoamyl p-methoxycinnamate;

[0968] The second UV-B filter is octyl salicylate;

[0969] The third UV-B filter is diethylhexyl butyramido triazone; and

[0970] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0971] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

[0972] Aspect 74 provides a sunscreen composition according to any one of aspects 71 to 73, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0973] Aspect 75 provides a sunscreen composition according to aspect 74, wherein the composition comprises from about 25% to about 2827% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0974] Aspect 76 provides a sunscreen composition according to aspect 75, wherein the composition comprises from about 26% to about 27% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.

[0975] Aspect 77 provides a sunscreen composition according to aspect 5, wherein

[0976] The UV-A filter is butyl methoxydibenzoylmethane;

[0977] The first UV-B filter is ethylhexyl triazone;

[0978] The second UV-B filter is octyl salicylate;

[0979] The third UV-B filter is isoamyl p-methoxycinnamate; and

[0980] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0981] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0982] Aspect 78 provides a sunscreen composition according to aspect 9, wherein

[0983] The UV-A filter is butyl methoxydibenzoylmethane;

[0984] The first UV-B filter is ethylhexyl triazone;

[0985] The second UV-B filter is octyl salicylate;

[0986] The third UV-B filter is diethylhexyl butyramido triazone; and

[0987] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0988] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0989] Aspect 79 provides a sunscreen composition according to aspect 13, wherein

[0990] The UV-A filter is butyl methoxydibenzoylmethane;

[0991] The first UV-B filter is isoamyl p-methoxycinnamate;

[0992] The second UV-B filter is octyl salicylate;

[0993] The third UV-B filter is diethylhexyl butyramido triazone; and

[0994] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[0995] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

[0996] Aspect 80 provides a sunscreen composition according to any one of aspects 77 to 79, wherein the one or more solubilizing agents are diisopropyl sebacate and dicaprylyl carbonate.

[0997] Aspect 81 provides a sunscreen composition according to aspect 80, wherein the composition comprises from about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0998] Aspect 82 provides a sunscreen composition according to aspect 81, wherein the composition comprises from about 18% to about 19% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.

[0999] Aspect 83 provides a sunscreen composition according to aspect 5, wherein

[1000] The UV-A filter is butyl methoxydibenzoylmethane;

[1001] The first UV-B filter is ethylhexyl triazone;

[1002] The second UV-B filter is octyl salicylate;

[1003] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1004] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1005] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[1006] Aspect 84 provides a sunscreen composition according to aspect 9, wherein

[1007] The UV-A filter is butyl methoxydibenzoylmethane;

[1008] The first UV-B filter is ethylhexyl triazone;

[1009] The second UV-B filter is octyl salicylate;

[1010] The third UV-B filter is diethylhexyl butyramido triazone; and

[1011] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1012] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[1013] Aspect 85 provides a sunscreen composition according to aspect 13, wherein

[1014] The UV-A filter is butyl methoxydibenzoylmethane;

[1015] The first UV-B filter is isoamyl p-methoxycinnamate;

[1016] The second UV-B filter is octyl salicylate;

[1017] The third UV-B filter is diethylhexyl butyramido triazone; and

[1018] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1019] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

[1020] Aspect 86 provides a sunscreen composition according to any one of aspects 83 to 85, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1021] Aspect 87 provides a sunscreen composition according to aspect 86, wherein the composition comprises from about 20% to about 23% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1022] Aspect 88 provides a sunscreen composition according to aspect 87, wherein the composition comprises from about 21% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1023] Aspect 89 provides a sunscreen composition according to aspect 5, wherein

[1024] The UV-A filter is butyl methoxydibenzoylmethane;

[1025] The first UV-B filter is ethylhexyl triazone;

[1026] The second UV-B filter is octyl salicylate;

[1027] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1028] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1029] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[1030] Aspect 90 provides a sunscreen composition according to aspect 9, wherein

[1031] The UV-A filter is butyl methoxydibenzoylmethane;

[1032] The first UV-B filter is ethylhexyl triazone;

[1033] The second UV-B filter is octyl salicylate;

[1034] The third UV-B filter is diethylhexyl butyramido triazone; and

[1035] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1036] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[1037] Aspect 91 provides a sunscreen composition according to aspect 13, wherein

[1038] The UV-A filter is butyl methoxydibenzoylmethane;

[1039] The first UV-B filter is isoamyl p-methoxycinnamate;

[1040] The second UV-B filter is octyl salicylate;

[1041] The third UV-B filter is diethylhexyl butyramido triazone; and

[1042] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1043] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[1044] Aspect 92 provides a sunscreen composition according to any one of aspects 89 to 91, wherein the one or more solubilizing agents is dibutyl adipate.

[1045] Aspect 93 provides a sunscreen composition according to aspect 92, wherein the composition comprises about 36% to about 39% dibutyl adipate.

[1046] Aspect 94 provides a sunscreen composition according to aspect 93, wherein the composition comprises from about 37% to about 38% of dibutyl adipate.

[1047] Aspect 95 provides a sunscreen composition according to aspect 5, wherein

[1048] The UV-A filter is butyl methoxydibenzoylmethane;

[1049] The first UV-B filter is ethylhexyl triazone;

[1050] The second UV-B filter is octyl salicylate;

[1051] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1052] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1053] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[1054] Aspect 96 provides a sunscreen composition according to aspect 9, wherein

[1055] The UV-A filter is butyl methoxydibenzoylmethane;

[1056] The first UV-B filter is ethylhexyl triazone;

[1057] The second UV-B filter is octyl salicylate;

[1058] The third UV-B filter is diethylhexyl butyramido triazone; and

[1059] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1060] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

[1061] Aspect 97 provides a sunscreen composition according to aspect 13, wherein

[1062] The UV-A filter is butyl methoxydibenzoylmethane;

[1063] The first UV-B filter is isoamyl p-methoxycinnamate;

[1064] The second UV-B filter is octyl salicylate;

[1065] The third UV-B filter is diethylhexyl butyramido triazone; and

[1066] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1067] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

[1068] Aspect 98 provides a sunscreen composition according to any one of aspects 94 to 97, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1069] Aspect 99 provides a sunscreen composition according to aspect 98, wherein the composition comprises from about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1070] Aspect 100 provides a sunscreen composition according to aspect 99, wherein the composition comprises from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1071] Aspect 101 provides a sunscreen composition according to any one of aspects 95 to 97, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.

[1072] Aspect 102 provides a sunscreen composition according to aspect 101, wherein the composition comprises from about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.

[1073] Aspect 103 provides a sunscreen composition according to aspect 102, wherein the composition comprises from about 26% to about 27% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.

[1074] Aspect 104 provides a sunscreen composition according to aspect 5, wherein

[1075] The UV-A filter is butyl methoxydibenzoylmethane;

[1076] The first UV-B filter is ethylhexyl triazone;

[1077] The second UV-B filter is octyl salicylate;

[1078] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1079] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1080] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:155:8.

[1081] Aspect 105 provides a sunscreen composition according to aspect 9, wherein

[1082] The UV-A filter is butyl methoxydibenzoylmethane;

[1083] The first UV-B filter is ethylhexyl triazone;

[1084] The second UV-B filter is octyl salicylate;

[1085] The third UV-B filter is diethylhexyl butyramido triazone; and

[1086] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1087] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[1088] Aspect 106 provides a sunscreen composition according to aspect 13, wherein

[1089] The UV-A filter is butyl methoxydibenzoylmethane;

[1090] The first UV-B filter is isoamyl p-methoxycinnamate;

[1091] The second UV-B filter is octyl salicylate;

[1092] The third UV-B filter is diethylhexyl butyramido triazone; and

[1093] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1094] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[1095] Aspect 107 provides a sunscreen composition according to any one of aspects 104 to 106, wherein the one or more solubilizing agents is dicaprylyl carbonate.

[1096] Aspect 108 provides a sunscreen composition according to aspect 107, wherein the composition comprises from about 26% to about 27% dicaprylyl carbonate.

[1097] Aspect 109 provides a sunscreen composition according to aspect 108, wherein the composition comprises from about 24% to about 26% of dicaprylyl carbonate.

[1098] Aspect 110 provides a sunscreen composition according to aspect 5, wherein

[1099] The UV-A filter is butyl methoxydibenzoylmethane;

[1100] The first UV-B filter is ethylhexyl triazone;

[1101] The second UV-B filter is octyl salicylate;

[1102] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1103] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1104] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

[1105] Aspect 111 provides a sunscreen composition according to aspect 9, wherein

[1106] The UV-A filter is butyl methoxydibenzoylmethane;

[1107] The first UV-B filter is ethylhexyl triazone;

[1108] The second UV-B filter is octyl salicylate;

[1109] The third UV-B filter is diethylhexyl butyramido triazone; and

[1110] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1111] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[1112] Aspect 112 provides a sunscreen composition according to aspect 13, wherein

[1113] The UV-A filter is butyl methoxydibenzoylmethane;

[1114] The first UV-B filter is isoamyl p-methoxycinnamate;

[1115] The second UV-B filter is octyl salicylate;

[1116] The third UV-B filter is diethylhexyl butyramido triazone; and

[1117] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1118] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

[1119] Aspect 113 provides a sunscreen composition according to any one of aspects 110 to 112, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1120] Aspect 114 provides a sunscreen composition according to aspect 113, wherein the composition comprises from about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1121] Aspect 115 provides a sunscreen composition according to aspect 114, wherein the composition comprises from about 25% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1122] Aspect 116 provides a sunscreen composition according to aspect 5, wherein

[1123] The UV-A filter is butyl methoxydibenzoylmethane;

[1124] The first UV-B filter is ethylhexyl triazone;

[1125] The second UV-B filter is octyl salicylate;

[1126] The third UV-B filter is isoamyl p-methoxycinnamate; and

[1127] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1128] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[1129] Aspect 117 provides a sunscreen composition according to aspect 9, wherein

[1130] The UV-A filter is butyl methoxydibenzoylmethane;

[1131] The first UV-B filter is ethylhexyl triazone;

[1132] The second UV-B filter is octyl salicylate;

[1133] The third UV-B filter is diethylhexyl butyramido triazone; and

[1134] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1135] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

[1136] Aspect 118 provides a sunscreen composition according to aspect 13, wherein

[1137] The UV-A filter is butyl methoxydibenzoylmethane;

[1138] The first UV-B filter is isoamyl p-methoxycinnamate;

[1139] The second UV-B filter is octyl salicylate;

[1140] The third UV-B filter is diethylhexyl butyramido triazone; and

[1141] The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyl triazine,

[1142] The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

[1143] Aspect 119 provides a sunscreen composition according to any one of aspects 116 to 118, wherein the one or more solubilizers are dibutyl adipate and decyl cocoate.

[1144] Aspect 120 provides a sunscreen composition according to aspect 119, wherein the composition comprises from about 31% to about 34% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1145] Aspect 121 provides a sunscreen composition according to aspect 120, wherein the composition comprises from about 32% to about 33% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.

[1146] Aspect 122 provides a method for protecting skin from sun damage, the method comprising applying to the skin the sunscreen composition according to any one of aspects 2 to 121.

[1147] Example 1

[1148] The following formulations can be prepared using methods known in the art.

[1149] Table 1: Sunscreen formulations.

[1150]

[1151] Example 2

[1152] The following formulations can be prepared using methods known in the art.

[1153] Table 2: Sunscreen formulations.

[1154]

[1155] Example 3

[1156] The following formulations can be prepared using methods known in the art.

[1157] Table 3: Sunscreen formulations.

[1158]

[1159] Example 4

[1160] The following formulations can be prepared using methods known in the art.

[1161] Table 4: Sunscreen formulations.

[1162]

[1163] Example 5

[1164] A facial cream having an SPF of at least 50 is prepared in the form of an emulsion. An oil phase is prepared comprising a UV filter composition as described herein, one or more solubilizers, thickeners, emulsifiers and waxes as described herein. The oil phase is added to an aqueous phase comprising water and glycerol under mixing. Rheology modifiers, pigments, preservatives, fragrances and active ingredients may be added.

[1165] Example 6

[1166] Various sunscreens were formulated with different concentrations of UV filters. Specifically, three sunscreens each containing a total of five UV filters were developed and compared to a sunscreen formulation containing nine UV filters. The formulations are presented below and the type and concentration of UV filters are listed.

[1167] Table 5: Comparison

[1168]

[1169] Table 6: Formula 1

[1170]

[1171] Table 7: Formula 2

[1172]

[1173] Table 8: Formula 3

[1174]

[1175] The sun protection factor (SPF), persistent pigment darkening (PPD), and SPF / PPD quotient were compared between the comparative formula, formula 1, formula 2, and formula 3. The results show that formula 1, formula 2, and formula 3 give equivalent or better performance than the comparative formula. It is worth noting that equivalent or better performance is achieved by formula 1, formula 2, and formula 3 having less total filter and a lower total concentration of filter by wt%. The results are Figure 1-6 Shown in.

[1176] Figure 1 It is shown that the in vivo SPF of Formula 1 and Formula 2 is substantially the same as the SPF of the Comparative Formula. Figure 2 It is shown that the PPD of Formula 1 is substantially the same as that of the Comparative Formula. Figure 3 It is shown that the SPF / PPD quotient of Formula 1 is substantially the same as that of the comparative formula. Figure 4 It is shown that the SPF of Formula 3 is improved over the comparative formula. Figure 5 It is shown that the PPD of Formula 3 is substantially the same as that of the Comparative Formula. Figure 6 It is shown that the SPF / PPD quotient of Formula 3 is substantially the same as that of the comparative formula.

[1177] All references, patents, or applications cited in this application, whether U.S. or foreign, are incorporated herein by reference as if written in their entirety. In the event of any inconsistency, the actual disclosure herein controls.

[1178] From the foregoing description, one skilled in the art can easily ascertain the essential characteristics of this invention, and without departing from the spirit and scope of the invention, can make various changes and modifications of the invention to adapt it to various usages and conditions.

Claims

1. A UV filter composition comprising: Three UV-B filters; UV-A filters; as well as UV-A + UV-B broadband filters.

2. A sunscreen composition comprising the UV filter composition according to claim 1.

3. The sunscreen composition according to claim 2, further comprising one or more solubilizers.

4. The sunscreen composition according to claim 3, wherein the one or more solubilizers are selected from the group consisting of diisopropyl sebacate, dicaprylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C12-15 alkyl benzoate and diethylhexyl succinate.

5. The sunscreen composition according to any one of claims 2 to 4, further comprising one or more emulsifiers.

6. A sunscreen composition according to claim 5, wherein the one or more emulsifiers are selected from polyglyceryl 6 stearate, polyglyceryl 6 behenate or potassium cetyl phosphate or acrylates vinyl neodecanoate crosspolymer.

7. The sunscreen composition according to any one of claims 2 to 4, wherein The UV-A filter includes butyl methoxydibenzoylmethane; The UV-B filter is selected from ethylhexyl triazone, octyl salicylate, isopentyl p-methoxycinnamate, and diethylhexyl butyramido triazone; and The broadband UV-A and UV-B filters include bis-ethylhexyloxyphenol methoxyphenyl triazine.

8. A sunscreen composition according to any one of claims 1 to 7, wherein the UV filter composition comprises: Three UV-B filters; UV-A filters; as well as UV-A + UV-B broadband filters.

9. The sunscreen composition according to any one of claims 2 to 4, wherein: The UV-A filter is butyl methoxydibenzoylmethane, The UV-B filter is ethylhexyl triazone, octyl salicylate, diethylhexyl butyramido triazone, and The broadband UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.

10. The sunscreen composition of claim 5, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

Images